My project will focus on role of roseophages for benthic roseobacters, their abundance in marine sediments, genetic composition and lifestyle. Using the genomic information of previously isolated benthic roseobacters the project aims to identify the presence of prophages. Phage-induction experiments will be conducted to determine characteristic parameters for phage-host interactions. Induced roseophages will be isolated and sequenced. Host genomes will be specifically screened for roseophage genes that are beneficial to the fitness of the host, while being presumably unimportant to roseophages. Furthermore, we will go back to the environment, to detect roseophage-specific signatures in metagenomes constructed from Pacific sediments and to quantify their distribution in original sediment samples by qPCR using phage-specific primers. Worldwide distribution of phages will be investigated by comparing known phage sequences by matching them to novel phage isolates.
|Since April 2019||PhD student (ICBM Oldenburg)|
Transregional Collaborative Research Centre (TTR 51) - Roseobacter - A2
|Oct. 2016 – Mar. 2019||Microbiology Master of Science (ICBM, Oldenburg)|
|“Isolation and genomic characterization of Roseophages from the North Sea”|
|Oct. 2013 – Sept. 2016|| |
Biology Bachelor of Science (University of Oldenburg)
“Der Einfluss von Exometaboliten und Vitaminbauteilen auf das Wachstum von Mikroorganismen”
Virus induction via mitomycin C, analysis of microbial diversity (DNA and RNA extraction, PCR, amplicon and genome sequence analysis), comparative genomics, metagenomic analyses of viruses, Isolation, cultivation and characterization of marine aerobic bacteria, physiological testings, sampling of sediment cores, microscopy ...
Heyerhoff, B., Nguyen, T., Hillebrand, H., Rhiel, E. (2019). On the morphology and predatory behavior of the dinoflagellate Oxyrrhis marina exposed to reduced salinity. European journal of protistology, 68, 37-47. DOI: 10.1016/j.ejop.2019.01.004
Contributions to conferences
VAAM 2019 Mainz, Germany: Large scale isolation of bacteriophages infecting marine Rhodobacteraceae V. Bischoff, B. Heyerhoff, A. Bögeholz, F. Zucker (Oldenburg/DE)A. Poehlein (Göttingen/DE), M. Simon, C. Moraru (Oldenburg/DE)
VAAM 2019 Mainz, Germany: Ascunsovirinae, a new Microviridae subfamily, infects alphaproteobacteria EMV06 from terrestrial and marine environments F. Zucker , V. Bischoff, B. Heyerhoff (Oldenburg/DE)A. Poehlein (Göttingen/DE), S. Roux (Walnut Creek, CA/US) F. Enault (Clermont-Ferrand/FR), M. Simon, C. Moraru (Oldenburg/DE)