apl. Prof. Dr. Karin Dedek
University of Oldenburg
Institute for Biology and Environmental Sciences

Neurosensorics/Animal Navigation

P/O Box 5634

26046 Oldenburg

+49 441 798 3425




Chetverikova R, Dautaj G, Schwigon L, Dedek K*, Mouritsen H* (2022) Double cones in the avian retina form an oriented mosaic which might facilitate magnetoreception and/or polarized light sensing. J R Soc Interface, in press. *Shared last authorship

Behrens C, Yadav SC, Korympidou MM, Zhang Y, Haverkamp S, Irsen S, Schaedler A, Franke K,  Vlasits A, Dedek K, Smith RG, Euler T, Berens P,  Schubert T. (2021) Retinal horizontal cells use different synaptic sites for global feedforward and local feedback signaling. Curr Biol. 32(3):545-558.e5. doi: 10.1016/j.cub.2021.11.055.


Einwich A, Seth PK, Bartölke R, Bolte P, Feederle R, Dedek K, Mouritsen H (2021) Localisation of cryptochrome 2 in the avian retina. J Comp Physiol A. doi: 10.1007/s00359-021-01506-1.

Seth PK, Balaji V, Dedek K (2021) The retinal circuitry for magnetoreception in migratory birds. Neuroforum. doi: 10.1515/nf-2021-0007.

Nemitz L, Dedek K, Janssen-Bienhold U (2021) Synaptic Remodeling in the Cone Pathway After Early Postnatal Horizontal Cell Ablation. Front Cell Neurosci 15, 657594. doi: 10.3389/fncel.2021.657594

Grothe T, Böhm T, Habashy K, Abdullaeva OS, Zablocki J, Lützen A, Dedek K, Schiek M, Ehrmann A (2021) Optical Index Matching, Flexible Electrospun Substrates for Seamless Organic Photocapacitive Sensors. Phys. Status Solidi B Basic Res 258(6), 2000543. doi: 10.1002/pssb.202000543

Günther A, Dedek K, Haverkamp S, Irsen S, Briggman K, Mouritsen H (2021) Double cones and the diverse connectivity of photoreceptors and bipolar cells in an avian retina. J Neurosci 41(23), 5015–5028. doi: 10.1523/JNEUROSCI.2495-20.2021.

Haverkamp S, Albert L, Balaji V, Němec P, Dedek K (2021) Expression of cell markers and transcription factors in the avian retina compared with that in the marmoset retina. J Comp Neurol 529(12), 3171–3193. doi: 10.1002/cne.25154.

Bolte P, Einwich A, Seth PK, Chetverikova R, Heyers D, Wojahn I, Janssen-Bienhold U, Feederle R, Hore P, Dedek K, Mouritsen H (2021) Cryptochrome 1a localisation in light- and dark-adapted retinae of several migratory and non-migratory bird species: no signs of light-dependent activation. Ethol Ecol Evol  33(3), pp. 248–272. doi: 10.1080/03949370.2020.1870571.


Tetenborg S, Wang HY, Nemitz L, Depping A, Espejo AB, Aseervatham J, Bedford MT, Janssen-Bienhold U, O’Brien J, Dedek K (2020) Phosphorylation of Connexin36 near the C-terminus switches binding affinities for PDZ-domain and 14-3-3 proteins in vitro. Sci Rep 10(1):18378. doi: 10.1038/s41598-020-75375-0.

Einwich A, Dedek K, Seth PK, Laubinger S, Mouritsen H (2020) A novel isoform of cryptochrome 4 (Cry4b) is expressed in the retina of a night-migratory songbird. Sci Rep 10(1):15794.


Nemitz L, Dedek K, Janssen-Bienhold U (2019) Rod Bipolar Cells Require Horizontal Cells for Invagination Into the Terminals of Rod Photoreceptors. Front Cell Neurosci 13:423.

Tetenborg S, Yadav SC, Brüggen B, Zoidl GR, Hormuzdi SG, Monyer H, van Woerden G, Janssen-Bienhold U, Dedek K (2019) Localization of Retinal Ca2+/Calmodulin-dependent Kinase II-β (CaMKII-β) at Bipolar Cell Gap Junctions and Cross-reactivity of a Monoclonal Anti-CaMKII-β Antibody with Connexin36. Front Mol Neurosci 12:206.

Yadav Sc, Tetenborg S, Dedek K (2019) Gap Junctions in A8 Amacrine Cells Are Made of Connexin36 but Are Differently Regulated than Gap Junctions in AII Amacrine Cells. Front Mol Neurosci 12:99. doi: 10.3389/fnmol.2019.00099.


Abdullaeva OS, Balzer F, Schulz M, Parisi J, Lützen A, Dedek K, Schiek M (2018) Organic Photovoltaic Sensors for Photo-Capacitive Stimulation of Voltage-Gated Ion Channels in Neuroblastoma Cells. Adv Funct Mater  29(21),1805177. doi: 10.1002/adfm.201805177.

Meyer A, Yadav SC, Dedek K (2018) Phenotyping of Gap-Junctional Coupling. Methods Mol Biol 1753:249-259. doi: 10.1007/978-1-4939-7720-8_17.

Ströh S, Puller C, Swirski S, Hölzel MB, van der Linde LIS, Segelken J, Schultz K, Block C, Monyer H, Willecke K, Weiler R, Greschner M, Janssen-Bienhold U, Dedek K (2018) Eliminating glutamatergic input onto horizontal cells changes the dynamic range and receptive field organization of mouse retinal ganglion cells. J Neurosci 38(8):2015-2028. doi: 10.1523/JNEUROSCI.0141-17.2018.


Tetenborg S, Yadav SC, Hormuzdi SG, Monyer H, Janssen-Bienhold U, Dedek K (2017) Differential Distribution of Retinal Ca2+/Calmodulin-Dependent Kinase II (CaMKII) Isoforms Indicates CaMKII-β and -δ as Specific Elements of Electrical Synapses Made of Connexin36 (Cx36). Front Mol Neurosci 10:425. doi: 10.3389/fnmol.2017.00425.


Abdullaeva OS, Schulz M, Balzer F, Parisi J, Luetzen A, Dedek K, Schiek M (2016) Photoelectrical Stimulation of Neuronal Cells by an Organic Semiconductor-Eletrolyte Interface. Langmuir 32(33):8533-42.

Meyer A, Tetenborg S, Greb H, Segelken J, Dorgau B, Weiler R, Hormuzdi SG, Janssen-Bienhold U, Dedek K (2016) Connexin30.2: In Vitro Interaction with Connexin36 in HeLa Cells and Expression in AII Amacrine Cells and Intrinsically Photosensitive Ganglion Cells in the Mouse Retina. Front Mol Neurosci. 9:36. doi: 10.3389/fnmol.2016.00036.

Brüggen B, Kremser C, Bickert A, Ebel P, Vom Dorp K, Schultz K, Dörmann P, Willecke K, Dedek K (2016) Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea. Eur J Neurosci 44(1):1700-13. doi: 10.1111/ejn.13260.


Bolte P, Herrling R, Dorgau B, Schultz K, Feigenspan A, Weiler R, Dedek K*, Janssen-Bienhold U* (2015) Expression and localization of connexins in the outer retina of the mouse. J Mol Neurosci 58(2):178-92. doi: 10.1007/s12031-015-0654-y. *shared last authorship

Dorgau B, Herrling R, Schultz K, Greb H, Segelken J, Ströh S, Bolte P, Weiler R, Dedek K*, Janssen-Bienhold U* (2015) Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions. J Comp Neurol 523(14):2062-81. *shared last authorship.

Lee SCS, Meyer A, Schubert T, Hüser L, Dedek K, Haverkamp S (2015) Morphology and connectivity of the small bistratified A8 amacrine cell in the mouse retina. J Comp Neurol 523(10):1529-47.


Brüggen B, Meyer A, Boven F, Weiler R, Dedek K (2014) Type 2 wide-field amacrine cells in TH::GFP mice show a homogenous synapse distribution and contact small ganglion cells. Eur J Neurosci 41(6):734-47.

Arango-Gonzalez B, Trifunovic, D, Sahaboglu A, Kranz K, Michalakis S, Farinelli P, Koch S, Koch F, Cottet S, Janssen-Bienhold U, Dedek K, Biel M, Zrenner E, Euler T, Ekström P, Ueffing M, Paquet-Durand F (2014) Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration. PLoS ONE 9(11):e112142.

Kemmler R, Schultz K, Dedek K, Euler T, Schubert T (2014) Differential regulation of cone calcium signals by different horizontal cell feedback mechanisms in the mouse retina. J Neurosci 34(35):11826-43.

Meyer A, Hilgen G, Dorgau B, Sammler EM, Weiler R, Monyer H, Dedek K*, Hormuzdi SG* (2014) AII amacrine cells discriminate between heterocellular and homocellular locations when assembling connexin36-containing gap junctions. J Cell Sci 127:1190-1202. *shared last authorship.


Ströh S, Sonntag S, Janssen-Bienhold U, Schultz K, Cimiotti K, Weiler R, Willecke K, Dedek K (2013) Cell-specific Cre recombinase expression allows selective ablation of glutamate receptors from mouse horizontal cells. PLoS One (12):e83076.

Knop GC, Pottek M, Monyer H, Weiler R, Dedek K (2013) Morphological and physiological properties of enhanced green fluorescent protein (EGFP)-expressing wide-field amacrine cells in the ChAT-EGFP mouse line. Eur J Neurosci 39(5):800-10.

Kranz K, Paquet-Durand F, Weiler R, Janssen-Bienhold U, Dedek K (2013) Testing for a gap junction-mediated bystander effect in retinitis pigmentosa: secondary cone death is not altered by deletion of connexin36 from cones. PLoS One 8(2):e57163.

Kranz K, Dorgau B, Pottek M, Herrling R, Schultz K, Bolte P, Monyer H, Penuela S, Laird DW, Dedek K, Weiler R, Janssen-Bienhold U (2013) Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knock-out. J Comp Neurol 521(5):1119-35.


Hilgen G, Huebner AK, Tanimoto N, Sothilingam V, Seide C, Garcia Garrido M, Schmidt KF, Seeliger MW, Löwel S, Weiler R, Hübner CA, Dedek K (2012) Lack of the sodium-driven chloride bicarbonate exchanger NCBE impairs visual function in the mouse retina. PLoS One 7(10): e46155.

Sonntag S*, Dedek K*, Dorgau B, Schultz K, Schmidt KF, Cimiotti K, Weiler R, Löwel S, Willecke K, Janssen-Bienhold U (2012) Ablation of retinal horizontal cells from adult mice leads to rod degeneration and remodeling in the outer retina. J Neurosci 32(31):10713-24. *shared first authorship.

Landgraf I, Mühlhans J, Dedek K, Reim K, Brandstätter JH, Ammermüller J (2012) The absence of Complexin 3 and Complexin 4 differentially impacts the ON and OFF pathways in mouse retina. Eur J Neurosci 36(4):2470-81.


Pottek M, Knop GC, Weiler R, Dedek K (2011) Electrophysiological Characterization of GFP-Expressing Cell Populations in the Intact Retina. J Vis Exp 57(e3457).

Knop GC, Feigenspan A, Weiler R, Dedek K (2011) Inputs underlying the ON-OFF light responses of type 2 wide-field amacrine cells in TH::GFP mice. J Neurosci 31(13):4780-91.

Hilgen G, von Maltzahn J, Willecke K, Weiler R, Dedek K (2011) Subcellular Distribution of Connexin45 in OFF Bipolar Cells of the Mouse Retina. J Comp Neurol 519(3):433-50.


Pérez de Sevilla Müller L, Dedek K, Janssen-Bienhold U, Meyer A, Kreuzberg MM, Lorenz S, Willecke K, Weiler R (2010) Expression and modulation of connexin30.2, a novel gap junction protein in the mammalian retina. Vis Neurosci 27(3-4):91-101.

Feigenspan A, Dedek K, Schröer U, Weiler R, Thanos S (2010) Expression of voltage-gated sodium channels in growth cones of the regenerating rat retina. Invest Ophthalmol Vis Sci 51(3):1789-99.

Dedek K, Breuninger T, Pérez de Sevilla Müller L, Maxeiner S, Willecke K, Euler T, Weiler R (2009) A novel type of interplexiform amacrine cells in the mouse retina. Eur J Neurosci 30(2):217-28.

Janssen-Bienhold U, Trümpler J, Hilgen G, Schultz K, Pérez de Sevilla Müller L, Sonntag S, Dedek K, Dirks P, Willecke K,  Weiler R (2009) Connexin57 is expressed in dendro-dendritic and axo-axonal gap junctions of mouse horizontal cells and its distribution is modulated by light. J Comp Neurol 513(4):363-74.

Trümpler J, Dedek K, Schubert T, Pérez de Sevilla Müller L, Seeliger M, Humphries P, Biel M, Weiler R (2008) Rod and cone contributions to horizontal cell light responses in the mouse retina. J Neurosci 28(27):6818-25.

Dedek K, Pandarinath C, Alam NM, Wellershaus K, Schubert T, Willecke K, Prusky GT, Weiler R, Nirenberg S (2008) Ganglion cell adaptability: does the coupling of horizontal cells play a role? PLoS One 3(3):e1714.

Dedek K, Schultz K, Pieper M, Dirks P, Maxeiner S, Willecke K, Weiler R, Janssen-Bienhold U (2006) Localization of a heterotypic gap junction composed of connexin36 and connexin45 in the rod pathway of the mouse retina. Eur J Neurosci 24(6):1675-86.

Shelley J, Dedek K, Schubert T, Feigenspan A, Schultz K, Hombach S, Willecke K, Weiler R. (2006) Horizontal cell receptive fields are reduced in connexin57-deficient mice. Eur J Neurosci 23(12):3176-86.

Kharkovets T, Dedek K, Maier H, Schweizer M, Khimich D, Nouvian R, Vardanyan V, Leuwer R, Moser T, Jentsch TJ (2006) Mice with modified KCNQ4 potassium channels as models for slowly progressing human deafness. EMBO J 8:25(3):642-52.

Maxeiner S*, Dedek K*, Janssen-Bienhold U, Ammermuller J, Brune H, Kirsch T, Pieper M, Degen J, Kruger O, Willecke K, Weiler R (2005) Deletion of connexin45 in mouse retinal neurons disrupts the rod/cone signaling pathway between AII amacrine and ON cone bipolar cells and leads to impaired visual transmission. J Neurosci 25:566-76. *shared first authorship.

Huber SM, Duranton C, Henke G, Van De Sand C, Heussler V, Shumilina E, Sandu CD, Tanneur V, Brand V, Kasinathan RS, Lang KS, Kremsner PG, Hubner CA, Rust MB, Dedek K, Jentsch TJ, Lang F (2004) Plasmodium induces swelling-activated ClC-2 anion channels in the host erythrocyte. J Biol Chem 279:41444-52.

Dedek K, Fusco L, Teloy N, Steinlein OK (2003) Neonatal convulsions and epileptic encephalopathy in an Italian family with a missense mutation in the fifth transmembrane region of KCNQ2. Epilepsy Res 54:21-7.

Dedek K, Waldegger S (2001) Colocalization of KCNQ1/KCNE channel subunits in the mouse gastrointestinal tract. Pflugers Arch 442:896-902.

Dedek K, Kunath B, Kananura C, Reuner U, Jentsch TJ, Steinlein OK (2001) Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel. Proc Natl Acad Sci U S A 98:12272-7.

(Stand: 20.04.2022)