Die hier angezeigten Termine und Veranstaltungen werden dynamisch aus Stud.IP heraus angezeigt.

Daher kontaktieren Sie bei Fragen bitte direkt die Person, die unter dem Punkt Lehrende/Dozierende steht.

Veranstaltung

Semester: Sommersemester 2023

6.04.150.005 Novel immunomodulatory tripeptides for the in vitro treatment of murine immune and endothelial cells -  


Veranstaltungstermin | Raum

    Veranstaltungsort

    • Please contact Dr. Nadine Mykicki for individual timing and further information (during office hours or by e-mail).

    Beschreibung

    KdPT is a tripeptide structurally related to the C-terminal amino acids of alpha-melanocyte-stimulating hormone, which was previously shown to exhibit anti-inflammatory effects in various inflammatory diseases. However, due to its unfavourable physical and chemical properties KdPT is for instance not suitable for topical application. Hence, KdPT was modified to improve its physical and chemical properties. To analyze the effect of the KdPT derivatives, phenotype, function and migratory activity will be analyzed in primary mouse immune cells by multicolor flow cytometry, multiplex bead assays or quantitative PCRs. Furthermore, the effect of the anti-inflammatory tripeptide on mouse endothelial cells will be analyzed by performing immunofluorescence staining and (if time is available) and transendothelial electrical resistance (TEER) assays.

    Lehrende

    SWS
    --

    Art der Lehre
    Ausschließlich Präsenz

    Lehrsprache
    deutsch und englisch

    (Stand: 19.01.2024)  | 
    Zum Seitananfang scrollen Scroll to the top of the page