Kontakt

Direktor

Prof. Dr.-Ing. Andreas Hein

Verwaltung

Dipl.Ges.oec. David Saß

+49 (0)441 798-2685

Geschäftsstelle

Imke Garten

+49 (0)441 798-2772

+49 (0)441 798-5824

Postanschrift

Carl von Ossietzky Universität Oldenburg
Department für Versorgungsforschung
Fakultät VI - Medizin und Gesundheitswissenschaften
Ammerländer Heerstr. 114-118
26129 Oldenburg

Besucheranschrift

Campus Haarentor, Gebäude V04
Ammerländer Heerstraße 140
26129 Oldenburg

Publikationen

Publikationen

  • [article] bibtex
    M. Weßel und M. Schweda, "Recognizing the Diverse Faces of Later Life. Old Age as a Category of Intersectional Analysis in Medical Ethics" Journal of Medicine and Philosophy, im Erscheinen, 2021.
    @article{Weel.imErscheinen2021,
      author = {We{\ss}el, Merle and Schweda, Mark},
      year = {im Erscheinen, 2021},
      title = {Recognizing the Diverse Faces of Later Life. Old Age as a Category of Intersectional Analysis in Medical Ethics},
      journal = {Journal of Medicine and Philosophy} }
  • [article] bibtex
    M. Schweda, T. Kirste, A. Hein, und S. Teipel, "The Emergence of Co-Intelligent Monitoring and Assistive Technologies in Dementia Care -- An Outline of Technological Trends and Ethical Aspects" Bioethica Forum, im Erscheinen, 2020.
    @article{Schweda.imErscheinen2020b,
      author = {Schweda, Mark and Kirste, Thomas and Hein, Andreas and Teipel, Stefan},
      year = {im Erscheinen, 2020},
      title = {The Emergence of Co-Intelligent Monitoring and Assistive Technologies in Dementia Care -- An Outline of Technological Trends and Ethical Aspects},
      issn = {1662-601X},
      journal = {Bioethica Forum} }
  • [incollection] bibtex
    L. Pfaller und M. Schweda, "\glqqSuccessful Aging\grqq als Kristallisationspunkt gerontologischer Selbstverständigungsdiskurse" in Kulturgerontologie. Kulturalistische Perspektiven auf das Alter(n) im deutschsprachigen Raum, Kolland, F., Gallistl, V., und Parisot, V., Eds., , im Erscheinen, 2020.
    @incollection{Pfaller.imErscheinen2020,
      author = {Pfaller, Larissa and Schweda, Mark},
      title = {{\glqq}Successful Aging{\grqq} als Kristallisationspunkt gerontologischer Selbstverst{\"a}ndigungsdiskurse},
      editor = {Kolland, Franz and Gallistl, Vera and Parisot, Viktoria},
      booktitle = {Kulturgerontologie. Kulturalistische Perspektiven auf das Alter(n) im deutschsprachigen Raum},
      year = {im Erscheinen, 2020} }
  • [incollection] bibtex
    M. Weßel, N. Ellerich-Groppe, und M. Schweda, "Stereotyping of social robots in eldercare: An explorative analysis of ethical problems and possible solutions" in Proceedings of the Robophilosophy Conference Series, Amsterdam: IOS Press, im Erscheinen, 2020.
    @incollection{Weel.imErscheinen2020,
      author = {We{\ss}el, Merle and Ellerich-Groppe, Niklas and Schweda, Mark},
      title = {Stereotyping of social robots in eldercare: An explorative analysis of ethical problems and possible solutions},
      publisher = {{IOS Press}},
      booktitle = {Proceedings of the Robophilosophy Conference Series},
      year = {im Erscheinen, 2020},
      address = {Amsterdam} }
  • [incollection] bibtex
    M. Schweda und L. Pfaller, "Responsibilization of aging? An ethical analysis of the moral economy of prevention" in Preventing old age and decline? Critical observations on aging and dementia, Leibing, A. und Schicktanz, S., Eds., Oxford, New York: Berghahn, im Erscheinen, 2020.
    @incollection{Schweda.imErscheinen2020,
      author = {Schweda, Mark and Pfaller, Larissa},
      title = {Responsibilization of aging? An ethical analysis of the moral economy of prevention},
      publisher = {Berghahn},
      editor = {Leibing, Annette and Schicktanz, Silke},
      booktitle = {Preventing old age and decline? Critical observations on aging and dementia},
      year = {im Erscheinen, 2020},
      address = {Oxford, New York} }
  • [article] bibtex
    M. Kohlhaas, L. K. Seidlmayer, und M. Kaspar, "A specialized system for arrhythmia detection for basic research in cardiology" Stud Health Technol Inform, [Im Druck].
    @article{Kohlhaas.ImDruck,
      author = {Kohlhaas, M and Seidlmayer, Lea Katharina and Kaspar, Mathias},
      year = {[Im Druck]},
      title = {A specialized system for arrhythmia detection for basic research in cardiology},
      issn = {1879-8365 (Electronic) 0926-9630 (Linking)},
      journal = {Stud Health Technol Inform} }
  • [book] bibtex
    M. Weßel, Rez. Berg, Annika, De samhällsbesvärliga. Förhandlingar om psykopati och kverulans i 1930- och 40-talens Sverige, Göteborg: Makadam Förlag, 2021.
    @book{Weel.2021,
      author = {We{\ss}el, Merle},
      year = {2021},
      title = {Rez. Berg, Annika, De samh{\"a}llsbesv{\"a}rliga. F{\"o}rhandlingar om psykopati och kverulans i 1930- och 40-talens Sverige},
      address = {G{\"o}teborg},
      publisher = {{Makadam F{\"o}rlag}} }
  • [article] bibtex
    B. Friedrich, S. Lau, L. Elgert, J. M. Bauer, und A. Hein, "A Deep Learning Approach for TUG and SPPB Score Prediction of (Pre-) Frail Older Adults on Real-Life IMU Data" Healthcare (Basel, Switzerland), vol. 9, iss. 2, 2021.
    @article{Friedrich.2021, abstract = {Since older adults are prone to functional decline, using Inertial-Measurement-Units (IMU) for mobility assessment score prediction gives valuable information to physicians to diagnose changes in mobility and physical performance at an early stage and increases the chances of rehabilitation. This research introduces an approach for predicting the score of the Timed Up {\&} Go test and Short-Physical-Performance-Battery assessment using IMU data and deep neural networks. The approach is validated on real-world data of a cohort of 20 frail or (pre-) frail older adults of an average of 84.7 years. The deep neural networks achieve an accuracy of about 95{\%} for both tests for participants known by the network.},
      author = {Friedrich, Bj{\"o}rn and Lau, Sandra and Elgert, Lena and Bauer, J{\"u}rgen M. and Hein, Andreas},
      year = {2021},
      title = {A Deep Learning Approach for TUG and SPPB Score Prediction of (Pre-) Frail Older Adults on Real-Life IMU Data},
      volume = {9},
      number = {2},
      issn = {2227-9032},
      journal = {Healthcare (Basel, Switzerland)},
      doi = {10.3390/healthcare9020149},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912931},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33540555} }
  • [article] bibtex
    A. A. Zeleke, T. Naziyok, F. Fritz, L. Christianson, und R. Röhrig, "Data Quality and Cost-effectiveness Analyses of Electronic and Paper-Based Interviewer-Administered Public Health Surveys: Systematic Review" Journal of medical Internet research, vol. 23, iss. 1, p. 21382, 2021.
    @article{Zeleke.2021, abstract = {BACKGROUND A population-level survey (PLS) is an essential and standard method used in public health research that supports the quantification of sociodemographic events, public health policy development, and intervention designs. Data collection mechanisms in PLS seem to be a significant determinant in avoiding mistakes. Using electronic devices such as smartphones and tablet computers improves the quality and cost-effectiveness of public health surveys. However, there is a lack of systematic evidence to show the potential impact of electronic data collection tools on data quality and cost reduction in interviewer-administered surveys compared with the standard paper-based data collection system. OBJECTIVE This systematic review aims to evaluate the impact of the interviewer-administered electronic data collection methods on data quality and cost reduction in PLS compared with traditional methods. METHODS We conducted a systematic search of MEDLINE, CINAHL, PsycINFO, the Web of Science, EconLit, Cochrane CENTRAL, and CDSR to identify relevant studies from 2008 to 2018. We included randomized and nonrandomized studies that examined data quality and cost reduction outcomes, as well as usability, user experience, and usage parameters. In total, 2 independent authors screened the title and abstract, and extracted data from selected papers. A third author mediated any disagreements. The review authors used EndNote for deduplication and Rayyan for screening. RESULTS Our search produced 3817 papers. After deduplication, we screened 2533 papers, and 14 fulfilled the inclusion criteria. None of the studies were randomized controlled trials; most had a quasi-experimental design, for example, comparative experimental evaluation studies nested on other ongoing cross-sectional surveys. A total of 4 comparative evaluations, 2 pre-post intervention comparative evaluations, 2 retrospective comparative evaluations, and 4 one-arm noncomparative studies were included. Meta-analysis was not possible because of the heterogeneity in study designs, types, study settings, and level of outcome measurements. Individual paper synthesis showed that electronic data collection systems provided good quality data and delivered faster compared with paper-based data collection systems. Only 2 studies linked cost and data quality outcomes to describe the cost-effectiveness of electronic data collection systems. Field data collectors reported that an electronic data collection system was a feasible, acceptable, and preferable tool for their work. Onsite data error prevention, fast data submission, and easy-to-handle devices were the comparative advantages offered by electronic data collection systems. Challenges during implementation included technical difficulties, accidental data loss, device theft, security concerns, power surges, and internet connection problems. CONCLUSIONS Although evidence exists of the comparative advantages of electronic data collection compared with paper-based methods, the included studies were not methodologically rigorous enough to combine. More rigorous studies are needed to compare paper and electronic data collection systems in public health surveys considering data quality, work efficiency, and cost reduction. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID) RR2-10.2196/10678.},
      author = {Zeleke, Atinkut Alamirrew and Naziyok, Tolga and Fritz, Fleur and Christianson, Lara and R{\"o}hrig, Rainer},
      year = {2021},
      title = {Data Quality and Cost-effectiveness Analyses of Electronic and Paper-Based Interviewer-Administered Public Health Surveys: Systematic Review},
      pages = {e21382},
      volume = {23},
      number = {1},
      journal = {Journal of medical Internet research},
      doi = {10.2196/21382},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33480859},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7864777} }
  • [article] bibtex
    M. Schweda und S. Schicktanz, "Ethische Aspekte co-intelligenter Assistenztechnologien in der Versorgung von Menschen mit Demenz" Psychiatr Prax, vol. 48, iss. S 01, p. s37-s41, 2021.
    @article{Schweda.2021, abstract = {Smart assistive technologies are increasingly discussed as a solution for the care of people with dementia. The article considers central ethical challenges of the use of such systems. It focuses on issues of privacy and empowerment. Intelligente technische Assistenzsysteme werden zunehmend als L{\"o}sung f{\"u}r die Versorgung von Menschen mit Demenz diskutiert. Der Beitrag betrachtet zentrale ethische Herausforderungen des Einsatzes derartiger Assistenzsysteme. Dabei konzentriert er sich auf Fragen der Privatheit und des Empowerments.},
      author = {Schweda, Mark and Schicktanz, Silke},
      year = {2021},
      title = {Ethische Aspekte co-intelligenter Assistenztechnologien in der Versorgung von Menschen mit Demenz},
      pages = {S37-S41},
      volume = {48},
      number = {S 01},
      issn = {0303-4259},
      journal = {Psychiatr Prax},
      doi = {10.1055/a-1369-3178},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33652486} }
  • [article] bibtex
    M. Ahmad, J. I. Glitza, F. Müller-von-Aschwege, A. Hein, und B. Cauchi, "Pulse Transit Time Estimation for Blood Pressure Meas-urement in Patients Implanted with a Left Ventricular Assist Device" Pervasive Health, 2020.
    @article{Ahmad.2020,
      author = {Ahmad, M. and Glitza, Jenny Inge and M{\"u}ller-von-Aschwege, Frerk and Hein, Andreas and Cauchi, Benjamin},
      year = {2020},
      title = {Pulse Transit Time Estimation for Blood Pressure Meas-urement in Patients Implanted with a Left Ventricular Assist Device},
      journal = {Pervasive Health} }
  • [article] bibtex
    B. Friedrich, E. Steen, S. Fudickar, und A. Hein, "Assessing the Mobility of Elderly People in Domestic Smart Home Environments" Computer Science & Information Technology (CS & IT), 2020.
    @article{Friedrich.2020b,
      author = {Friedrich, Bj{\"o}rn and Steen, Enno-Edzard and Fudickar, Sebastian and Hein, Andreas},
      year = {2020},
      title = {Assessing the Mobility of Elderly People in Domestic Smart Home Environments},
      journal = {Computer Science {\&} Information Technology (CS {\&} IT)} }
  • [inproceedings] bibtex
    C. Fifelski-von Böhlen, A. Brinkmann, S. Mävers, S. Hellmers, und A. Hein, "Virtual Reality Integrated Multi Depth Camera System for Health Care Applications" in Proc. 3rd IEEE International conference on Artificial Intelligence & Virtual Reality (AIVR 2020), 2020.
    @inproceedings{FifelskivonBohlen.2020,
      author = {{Fifelski-von B{\"o}hlen},
      Conrad and Brinkmann, Anna and M{\"a}vers, Stephan and Hellmers, Sandra and Hein, Andreas},
      title = {Virtual Reality Integrated Multi Depth Camera System for Health Care Applications},
      booktitle = {3rd IEEE International conference on Artificial Intelligence {\&} Virtual Reality (AIVR 2020)},
      year = {2020} }
  • [inproceedings] bibtex
    C. Kowalski, P. Gliesche, C. Fifelski-von Böhlen, A. Brinkmann, und A. Hein, "Towards Physical Human-Robot Interaction using Force Support for Nursing Care Bed Activities" in Proc. IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), 2020.
    @inproceedings{Kowalski.2020b,
      author = {Kowalski, Christian and Gliesche, Pascal and {Fifelski-von B{\"o}hlen},
      Conrad and Brinkmann, Anna and Hein, Andreas},
      title = {Towards Physical Human-Robot Interaction using Force Support for Nursing Care Bed Activities},
      booktitle = {IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)},
      year = {2020} }
  • [article] bibtex
    H. Jacobs, J. Callhoff, K. Albrecht, A. Postler, J. Saam, T. Lange, J. Goronzy, K. Günther, und F. Hoffmann, "Use of physiotherapy in patients with osteoarthritis in Germany--an analysis of a linkage of claims and survey data (from the PROCLAIR project)" Arthritis Care & Research, 2020.
    @article{Jacobs.2020,
      author = {Jacobs, Hannes and Callhoff, Johanna and Albrecht, Katinka and Postler, Anne and Saam, Joachim and Lange, Toni and Goronzy, Jens and G{\"u}nther, Klaus--Peter and Hoffmann, Falk},
      year = {2020},
      title = {Use of physiotherapy in patients with osteoarthritis in Germany--an analysis of a linkage of claims and survey data (from the PROCLAIR project)},
      issn = {2151-464X},
      journal = {Arthritis Care {\&} Research} }
  • [article] bibtex
    I. Seeger, A. Klausen, S. Thate, F. Flake, O. Peters, W. Rempe, M. Peter, F. Scheinichen, U. Günther, und R. Röhrig, "Community emergency paramedics as an innovative resource in emergency care-first results of an observational study" NOTFALL & RETTUNGSMEDIZIN, 2020.
    @article{Seeger.2020b,
      author = {Seeger, Insa and Klausen, Andreas and Thate, S. and Flake, F. and Peters, O. and Rempe, W. and Peter, M. and Scheinichen, F. and G{\"u}nther, U. and R{\"o}hrig, Rainer},
      year = {2020},
      title = {Community emergency paramedics as an innovative resource in emergency care-first results of an observational study},
      issn = {1434-6222},
      journal = {NOTFALL {\&} RETTUNGSMEDIZIN} }
  • [article] bibtex
    M. Weßel, "Rez. Fürholzer, Katharina: Das Ethos des Partographen. Literatur- und medizinethische Dimensionen von Krankenbiographien. Universitätsverlage Winter 2019, 286 S" Nordeuropaforum, pp. 44-46, 2020.
    @article{Weel.2020b,
      author = {We{\ss}el, Merle},
      year = {2020},
      title = {Rez. F{\"u}rholzer, Katharina: Das Ethos des Partographen. Literatur- und medizinethische Dimensionen von Krankenbiographien. Universit{\"a}tsverlage Winter 2019, 286 S},
      pages = {44--46},
      journal = {Nordeuropaforum} }
  • [book] bibtex
    Ageing and Human Nature: Perspectives from Philosophical, Theological, and Historical Anthropology, Schweda, M., Coors, M., und Bozzaro, C., Eds., Cham: Springer, 2020.
    @book{Schweda.2020, year = {2020},
      title = {Ageing and Human Nature: Perspectives from Philosophical, Theological, and Historical Anthropology},
      address = {Cham},
      publisher = {Springer},
      editor = {Schweda, Mark and Coors, Michael and Bozzaro, Claudia} }
  • [inproceedings] bibtex
    C. Fifelski-von Böhlen, A. Brinkmann, C. Kowalski, O. Meyer, S. Hellmers, und A. Hein, "Reducing Caregiver's Physical Strain in Manual Patient Transfer with Robot Support" in Proc. 2020 5th International Conference on Automation, Control and Robotics Engineering (CACRE), 2020, pp. 189-194.
    @inproceedings{FifelskivonBohlen.2020b,
      author = {{Fifelski-von B{\"o}hlen},
      Conrad and Brinkmann, Anna and Kowalski, Christian and Meyer, Ole and Hellmers, Sandra and Hein, Andreas},
      title = {Reducing Caregiver's Physical Strain in Manual Patient Transfer with Robot Support},
      pages = {189--194},
      booktitle = {2020 5th International Conference on Automation, Control and Robotics Engineering (CACRE)},
      year = {2020} }
  • [article] bibtex
    C. Bartels, A. Kögel, M. Schweda, J. Wiltfang, M. Pentzek, S. Schicktanz, und A. Schneider, "Use of Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Risk in Mild Cognitive Impairment and Subjective Cognitive Decline in Routine Clinical Care in Germany" Journal of Alzheimer's Disease, vol. Preprint, pp. 1-12, 2020.
    @article{Bartels.2020,
      author = {Bartels, Claudia and K{\"o}gel, Anna and Schweda, Mark and Wiltfang, Jens and Pentzek, Michael and Schicktanz, Silke and Schneider, Anja},
      year = {2020},
      title = {Use of Cerebrospinal Fluid Biomarkers of Alzheimer's Disease Risk in Mild Cognitive Impairment and Subjective Cognitive Decline in Routine Clinical Care in Germany},
      pages = {1--12},
      volume = {Preprint},
      journal = {Journal of Alzheimer's Disease} }
  • [article] bibtex
    S. Drolshagen, M. Pfingsthorn, P. Gliesche, und A. Hein, "Acceptance of Industrial Collaborative Robots by People with Disability in Sheltered Workshops" Frontiers in Robotics and AI, vol. 7, p. 173, 2020.
    @article{Drolshagen.2020,
      author = {Drolshagen, Sandra and Pfingsthorn, Max and Gliesche, Pascal and Hein, Andreas},
      year = {2020},
      title = {Acceptance of Industrial Collaborative Robots by People with Disability in Sheltered Workshops},
      pages = {173},
      volume = {7},
      journal = {Frontiers in Robotics and AI} }
  • [article] bibtex
    P. Gliesche, T. Krick, M. Pfingsthorn, S. Drolshagen, C. Kowalski, und A. Hein, "Kinesthetic Device vs. Keyboard/Mouse: a Comparison in Home Care Telemanipulation" Frontiers in Robotics and AI, vol. 7, p. 172, 2020.
    @article{Gliesche.2020b,
      author = {Gliesche, Pascal and Krick, Tobias and Pfingsthorn, Max and Drolshagen, Sandra and Kowalski, Christian and Hein, Andreas},
      year = {2020},
      title = {Kinesthetic Device vs. Keyboard/Mouse: a Comparison in Home Care Telemanipulation},
      pages = {172},
      volume = {7},
      journal = {Frontiers in Robotics and AI} }
  • [article] bibtex
    K. Jobski, M. Dörks, C. Bantel, und F. Hoffmann, "Regional Differences in Opioid Prescribing in Germany--Results of an Analysis of Health Insurance Data of 57 Million Adult People" Journal of Pain Research, vol. 13, pp. 2483-2492, 2020.
    @article{Jobski.2020,
      author = {Jobski, Kathrin and D{\"o}rks, Michael and Bantel, Carsten and Hoffmann, Falk},
      year = {2020},
      title = {Regional Differences in Opioid Prescribing in Germany--Results of an Analysis of Health Insurance Data of 57 Million Adult People},
      pages = {2483--2492},
      volume = {13},
      journal = {Journal of Pain Research} }
  • [article] bibtex
    C. Kowalski und L. Ansmann, "Organisationsbezogene Versorgungsforschung" Onkologie heute, iss. 3, pp. 48-49, 2020.
    @article{Kowalski.2020,
      author = {Kowalski, Christoph and Ansmann, Lena},
      year = {2020},
      title = {Organisationsbezogene Versorgungsforschung},
      pages = {48--49},
      number = {3},
      journal = {Onkologie heute} }
  • M. Levelink, M. Voigt-Barbarowicz, und A. L. Brütt, "Priorities of patients, caregivers and health-care professionals for health research - A systematic review" Health Expect, 2020.
    @article{Levelink.2020,
      author = {Levelink, M. and Voigt-Barbarowicz, M. and Br{\"u}tt, Anna Levke},
      year = {2020},
      title = {Priorities of patients, caregivers and health-care professionals for health research - A systematic review},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/32643854},
      journal = {Health Expect},
      doi = {10.1111/hex.13090} }
  • [article] bibtex
    C. Rausch und F. Hoffmann, "Prescribing medications of questionable benefit prior to death: a retrospective study on older nursing home residents with and without dementia in Germany" European journal of clinical pharmacology, pp. 1-9, 2020.
    @article{Rausch.2020,
      author = {Rausch, Christian and Hoffmann, Falk},
      year = {2020},
      title = {Prescribing medications of questionable benefit prior to death: a retrospective study on older nursing home residents with and without dementia in Germany},
      pages = {1--9},
      issn = {1432-1041},
      journal = {European journal of clinical pharmacology} }
  • [article] bibtex
    M. Schweda, "Gab es eine Ritter-Schule? Zu einem Kapitel der Philosophiegeschichte der Bundesrepublik [auf Russisch]" Logos, vol. 6, pp. 207-238, 2020.
    @article{Schweda.2020c,
      author = {Schweda, Mark},
      year = {2020},
      title = {Gab es eine Ritter-Schule? Zu einem Kapitel der Philosophiegeschichte der Bundesrepublik [auf Russisch]},
      pages = {207--238},
      volume = {6},
      journal = {Logos} }
  • T. Seeralan, M. Härter, C. Koschnitzke, M. Scholl, S. Kohlmann, M. Lehmann, M. Eisele, L. E. Braunschneider, G. Marx, M. Scherer, B. Löwe, J. L. Magaard, und A. L. Brütt, "Patient involvement in developing a patient-targeted feedback intervention after depression screening in primary care within the randomized controlled trial GET.FEEDBACK.GP" Health Expect, 2020.
    @article{Seeralan.2020,
      author = {Seeralan, T. and H{\"a}rter, Martin and Koschnitzke, C. and Scholl, M. and Kohlmann, S. and Lehmann, M. and Eisele, M. and Braunschneider, L. E. and Marx, G. and Scherer, Martin and L{\"o}we, B. and Magaard, J. L. and Br{\"u}tt, Anna Levke},
      year = {2020},
      title = {Patient involvement in developing a patient-targeted feedback intervention after depression screening in primary care within the randomized controlled trial GET.FEEDBACK.GP},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/32286005},
      journal = {Health Expect},
      doi = {10.1111/hex.13039} }
  • [article] bibtex
    C. Stüwe und L. Ansmann, "Patientinnen in Tumorkonferenzen" mamazone MAG, iss. Juni, pp. 18-22, 2020.
    @article{Stuwe.2020,
      author = {St{\"u}we, C. and Ansmann, Lena},
      year = {2020},
      title = {Patientinnen in Tumorkonferenzen},
      pages = {18--22},
      number = {Juni},
      journal = {mamazone MAG} }
  • [article] bibtex
    T. Wolters, O. Wübbenhorst, C. Lüpkes, und A. Hein, "Generation of Fine Grained Demographic Information for Epidemiological Analysis" Digital Personalized Health and Medicine: Proceedings of MIE 2020, vol. 270, p. 233, 2020.
    @article{Wolters.2020,
      author = {Wolters, Timo and W{\"u}bbenhorst, Oke and L{\"u}pkes, Christian and Hein, Andreas},
      year = {2020},
      title = {Generation of Fine Grained Demographic Information for Epidemiological Analysis},
      pages = {233},
      volume = {270},
      journal = {Digital Personalized Health and Medicine: Proceedings of MIE 2020} }
  • [book] bibtex
    Gute Behandlung im Alter?, Frewer, A., Klotz, S., Herrler, C., und Bielefeldt, H., Eds., transcript Verlag, 2020.
    @book{Frewer.2020, year = {2020},
      title = {Gute Behandlung im Alter?},
      publisher = {{transcript Verlag}},
      isbn = {9783839451236},
      editor = {Frewer, Andreas and Klotz, Sabine and Herrler, Christoph and Bielefeldt, Heiner},
      doi = {10.14361/9783839451236} }
  • [incollection] bibtex
    A. Timmer, "Epidemiologie der chronisch entzündlichen Darmerkrankungen" in Chronisch entzündliche Darmerkrankungen in Klinik und Praxis, Hoffmann, J. C., Klump, B., Kroesen, A. J., und Siegmund, B., Eds., Springer Berlin Heidelberg, 2020.
    @incollection{Timmer.2020,
      author = {Timmer, Antje},
      title = {Epidemiologie der chronisch entz{\"u}ndlichen Darmerkrankungen},
      publisher = {{Springer Berlin Heidelberg}},
      editor = {Hoffmann, J. C. and Klump, B. and Kroesen, A. J. and Siegmund, B.},
      booktitle = {Chronisch entz{\"u}ndliche Darmerkrankungen in Klinik und Praxis},
      year = {2020} }
  • [inproceedings] bibtex
    P. Arizpe-Gomez, K. Harms, S. Fudickar, K. Janitzky, K. Witt, und A. Hein, "Preliminary Viability Test of a 3-D-Consumer-Camera-Based System for Automatic Gait Feature Detection in People with and without Parkinson ' s Disease" in Proc. Proceedings of IEEE International Conference on Healthcare Informatics (ICHI), 2020, pp. 1-7.
    @inproceedings{ArizpeGomez.2020, abstract = {Movement contains a large amount of cognitive, central-motor and musculoskeletal information that correlates directly with the general state of health. Approaches to automatic movement analysis, in particular to automatized gait analysis are of utmost relevance to offer modern technological support for health professionals. The purpose of this paper is to present the experimental setup and preliminary results of the viability test of the TEDIPA study, which will evaluate the comparability of Azure Kinect's consumer depth and color camera with the medical product for gait analysis GAITRite, regarding accuracy and precision when measuring key indicators of healthy and pathological gait. Index},
      author = {Arizpe-Gomez, Pedro and Harms, Kirsten and Fudickar, Sebastian and Janitzky, Kathrin and Witt, Karsten and Hein, Andreas},
      title = {Preliminary Viability Test of a 3-D-Consumer-Camera-Based System for Automatic Gait Feature Detection in People with and without Parkinson ' s Disease},
      pages = {1--7},
      booktitle = {Proceedings of IEEE International Conference on Healthcare Informatics (ICHI)},
      year = {2020} }
  • [article] bibtex
    A. Avian, S. Poggenburg, D. Schaffler-Schaden, K. Hoffmann, L. Sanftenberg, S. Loukanova, H. Bachler, S. Gehrke-Beck, M. Petek Ster, A. Becker, M. Herrmann, T. Frese, F. Gerlach, E. Zelko, M. Flamm, M. Roos, M. Freitag, J. Schirgi, A. Rieder, und A. Siebenhofer, "Attitudes of medical students to general practice: a multinational cross-sectional survey" Family practice, 2020.
    @article{Avian.2020, abstract = {BACKGROUND A shortage of general practitioners (GPs) is common to many European countries. To counteract this, it is essential to understand the factors that encourage or discourage medical students from choosing to become a GP. OBJECTIVE To evaluate medical students' attitudes towards general practice and to identify factors that discourage them from considering a career as a GP. METHODS In this multinational cross-sectional online survey, 29 284 students from nine German, four Austrian and two Slovenian universities were invited to answer a questionnaire consisting of 146 closed and 13 open-ended items. RESULTS Of the 4486 students that responded (response rate: 15.3{\%}), 3.6{\%} wanted to become a GP, 48.1{\%} were undecided and 34.6{\%} did not want to be a GP. Significant predictors for interest in becoming a GP were higher age [odds ratio (OR) = 1.06; 95{\%} confidence interval (CI) = 1.02-1.10], positive evaluation of the content of a GP's work (OR = 4.44; 95{\%} CI = 3.26-6.06), organizational aspects (OR = 1.42; 95{\%} CI = 1.13-1.78), practical experience of general practice (OR = 1.66; 95{\%} CI = 1.08-2.56) and the country of the survey [Slovenian versus German students (Reference): OR = 2.19; 95{\%} CI = 1.10-4.38; Austrian versus German students (Reference): OR = 0.50; 95{\%} CI = 0.32-0.79]. CONCLUSION Strategies to convince undecided students to opt for a career as a GP should include a positive representation of a GP's work and early and repeated experience of working in a general practice during medical school.},
      author = {Avian, Alexander and Poggenburg, Stephanie and Schaffler-Schaden, Dagmar and Hoffmann, Kathryn and Sanftenberg, Linda and Loukanova, Svetla and Bachler, Herbert and Gehrke-Beck, Sabine and {Petek Ster},
      Marija and Becker, Annette and Herrmann, Markus and Frese, Thomas and Gerlach, Ferdinand and Zelko, Erika and Flamm, Maria and Roos, Marco and Freitag, Michael and Schirgi, Julia and Rieder, Anita and Siebenhofer, Andrea},
      year = {2020},
      title = {Attitudes of medical students to general practice: a multinational cross-sectional survey},
      journal = {Family practice},
      doi = {10.1093/fampra/cmaa126},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33251543} }
  • [article] bibtex
    M. Baunacke, M. Schmidt, C. Groeben, A. Borkowetz, C. Thomas, R. Koch, F. Hoffmann, F. K. H. Chun, L. Weissbach, und J. Huber, "Treatment of post-prostatectomy urinary incontinence and erectile dysfunction: there is insufficient utilisation of care in German cancer survivors" World journal of urology, 2020.
    @article{Baunacke.2020, abstract = {PURPOSE Treatment of post-prostatectomy urinary incontinence (UI) and erectile dysfunction (ED) increases quality of life (QoL). Aim of our study was to evaluate the utilisation of care among patients with post-prostatectomy UI and ED in Germany. METHODS The HAROW study documented treatment of patients with localised prostate cancer ($\leq$ T2c) in Germany. 1260 patients underwent radical prostatectomy (RP). Patients answered validated questionnaires after a median follow-up of 6.3~years. Response rate was 76.8{\%}. RESULTS Median age at RP was 65 (IQR 60-69) years. 14{\%} (134/936) used more than one pad per day for UI. 25{\%} (26/104, 30 missing) of UI patients underwent surgery to improve continence. Of patients without surgery, 41{\%} (31/75) reported a moderate-to-severe issue concerning their incontinence with worse mental health and QoL. 81{\%} (755/936) patients were unable to have an erection firm enough for sexual intercourse. Of all ED patients, 40{\%} (319/793) used ED treatment regularly or tried it at least once. 49{\%} (243/499) of patients with interest in sex never tried ED treatment. In multivariate analysis, patients not using ED treatments were older ($\geq$ 70~years OR 4.1), and more often had preoperative ED (OR 2.3) and less interest in sex (OR 2.2). Nevertheless, 30{\%} (73/240) of these patients had moderate-to-severe issues with their ED reporting worse mental health and QoL. CONCLUSION Almost half of the patients without post-prostatectomy UI and ED treatment reported moderate-to-severe issues with a significant decrease in QoL. This indicates an insufficient utilisation of care in Germany.},
      author = {Baunacke, Martin and Schmidt, Maria-Luisa and Groeben, Christer and Borkowetz, Angelika and Thomas, Christian and Koch, Rainer and Hoffmann, Falk and Chun, Felix K. H. and Weissbach, Lothar and Huber, Johannes},
      year = {2020},
      title = {Treatment of post-prostatectomy urinary incontinence and erectile dysfunction: there is insufficient utilisation of care in German cancer survivors},
      journal = {World journal of urology},
      doi = {10.1007/s00345-020-03526-z},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33263177} }
  • J. Biesewig-Siebenmorgen, H. Diederichs-Egidi, G. Egidi, B. Engel, S. Heim, und G. Schiemann, "Wir wollen die Weiterbildung verbessern-aber was wollen eigentlich die ÄiW?" Zeitschrift für Allgemeinmedizin, vol. 6, pp. 246-250, 2020.
    @article{BiesewigSiebenmorgen.2020,
      author = {Biesewig-Siebenmorgen, J{\"u}rgen and Diederichs-Egidi, Heike and Egidi, G{\"u}nther and Engel, Bettina and Heim, Susanne and Schiemann, Guido},
      year = {2020},
      title = {Wir wollen die Weiterbildung verbessern-aber was wollen eigentlich die {\"A}iW?},
      url = {https://www.online-zfa.com/fileadmin/user_upload/ZFA_06_2020_Gesamt.pdf#page=8},
      pages = {246--250},
      volume = {6},
      journal = {Zeitschrift f{\"u}r Allgemeinmedizin} }
  • [article] bibtex
    B. Bohmeier, B. Schellenberger, A. Diekmann, N. Ernstmann, L. Ansmann, und C. Heuser, "Opportunities and limitations of shared decision making in multidisciplinary tumor conferences with patient participation - A qualitative interview study with providers" Patient education and counseling, 2020.
    @article{Bohmeier.2020, abstract = {OBJECTIVE The aim of this study was to examine opportunities and limitations of shared decision making in multidisciplinary tumor conferences with patient participation from the providers' perspective in breast and gynecological cancer centers. METHODS Semi-structured guideline-based expert interviews were conducted with providers from breast and gynecological cancer centers with and without patient participation in multidisciplinary tumor conferences. Interviews were transcribed, anonymized and analyzed using qualitative content analysis. RESULTS The providers (n = 30) reported that some process steps of shared decision making can be implemented in limited form and under certain conditions in multidisciplinary tumor conferences with patient participation. Above all, patients can potentially ask questions and contribute individual additional information and their preferences. CONCLUSION This study contributes first insights into the implementation of shared decision making in multidisciplinary tumor conferences with patient participation. From the providers' perspective, the implementation of shared decision making seems difficult under the current circumstances. Further studies, using patient experiences, participative observations or interventional designs, are required. PRACTICE IMPLICATIONS Despite the limited implementation of shared decision making in tumor conferences, patient participation can be advantageous as it can allow patients to ask questions and contribute individual additional information as well as their preferences.},
      author = {Bohmeier, Barbara and Schellenberger, Barbara and Diekmann, Annika and Ernstmann, Nicole and Ansmann, Lena and Heuser, Christian},
      year = {2020},
      title = {Opportunities and limitations of shared decision making in multidisciplinary tumor conferences with patient participation - A qualitative interview study with providers},
      journal = {Patient education and counseling},
      doi = {10.1016/j.pec.2020.09.007},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33051128} }
  • [article] bibtex
    E. Buhr, "#stayathome als Kolonialisierung der lokalen Privatheit? -- eine ethische Auseinandersetzung mit dem Wert des Privaten in Zeiten einer globalen Pandemie" Zeitschrift für Praktische Philosophie, vol. 7, iss. 2, pp. 385-416, 2020.
    @article{Buhr.2020,
      author = {Buhr, Eike},
      year = {2020},
      title = {{\#}stayathome als Kolonialisierung der lokalen Privatheit? -- eine ethische Auseinandersetzung mit dem Wert des Privaten in Zeiten einer globalen Pandemie},
      pages = {385--416},
      volume = {7},
      number = {2},
      journal = {Zeitschrift f{\"u}r Praktische Philosophie} }
  • [article] bibtex
    A. M. Fassmer, A. Pulst, G. Schmiemann, und F. Hoffmann, "Warum gleich ins Krankenhaus?" Gesundheit & Gesellschaft, vol. 23, iss. 9, pp. 33-37, 2020.
    @article{Fassmer.2020b,
      author = {Fassmer, Alexander Maximilian and Pulst, Alexandra and Schmiemann, Guido and Hoffmann, Falk},
      year = {2020},
      title = {Warum gleich ins Krankenhaus?},
      pages = {33--37},
      volume = {23},
      number = {9},
      journal = {Gesundheit {\&} Gesellschaft} }
  • [article] bibtex
    A. M. Fassmer, A. Pulst, G. Schmiemann, und F. Hoffmann, "Sex-Specific Differences in Hospital Transfers of Nursing Home Residents: Results from the HOspitalizations and eMERgency Department Visits of Nursing Home Residents (HOMERN) Project" International journal of environmental research and public health, vol. 17, iss. 11, p. 3915, 2020.
    @article{Fassmer.2020c,
      author = {Fassmer, Alexander Maximilian and Pulst, Alexandra and Schmiemann, Guido and Hoffmann, Falk},
      year = {2020},
      title = {Sex-Specific Differences in Hospital Transfers of Nursing Home Residents: Results from the HOspitalizations and eMERgency Department Visits of Nursing Home Residents (HOMERN) Project},
      pages = {3915},
      volume = {17},
      number = {11},
      journal = {International journal of environmental research and public health} }
  • [article] bibtex
    F. Hoffmann, D. Eggers, D. Pieper, H. Zeeb, und K. Allers, "An observational study found large methodological heterogeneity in systematic reviews addressing prevalence and cumulative incidence" Journal of Clinical Epidemiology, vol. 119, pp. 92-99, 2020.
    @article{Hoffmann.2020b,
      author = {Hoffmann, Falk and Eggers, Daniela and Pieper, Dawid and Zeeb, Hajo and Allers, Katharina},
      year = {2020},
      title = {An observational study found large methodological heterogeneity in systematic reviews addressing prevalence and cumulative incidence},
      pages = {92--99},
      volume = {119},
      issn = {0895-4356},
      journal = {Journal of Clinical Epidemiology} }
  • [article] bibtex
    F. Hoffmann, C. Bantel, F. T. von Rosen, und K. Jobski, "Regional Differences in Prescribing Patterns of Metamizole in Germany Based on Data from 70 Million Persons" International journal of environmental research and public health, vol. 17, iss. 11, p. 3892, 2020.
    @article{Hoffmann.2020c,
      author = {Hoffmann, Falk and Bantel, Carsten and {von Rosen},
      Frederik Tilmann and Jobski, Kathrin},
      year = {2020},
      title = {Regional Differences in Prescribing Patterns of Metamizole in Germany Based on Data from 70 Million Persons},
      pages = {3892},
      volume = {17},
      number = {11},
      journal = {International journal of environmental research and public health} }
  • [article] bibtex
    J. Koschate, L. Thieschäfer, U. Drescher, T. Zieschang, und U. Hoffmann, "Time-series analysis of heart rate and blood pressure in response to changes in work rate before and after 60 days of 6° head down tilt bed rest" European journal of applied physiology, 2020.
    @article{Koschate.2020, abstract = {PURPOSE Cardiovascular regulation during exercise, described using time series analysis, is expected to be attenuated after bed rest (BR) and this effect will be dampened by a reactive jumps countermeasure. METHODS Twenty subjects (29 $\pm$ 6~years, 23.6 $\pm$ 1.7~kg~m-2) were tested on a cycle ergometer 9~days (BDC-9) before the beginning of BR as well as 2 (R + 2) and 13~days (R + 13) after the end of BR, applying moderate pseudo-random binary (PRBS) work rate changes. Heart rate (HR) and mean arterial blood pressure (mBP) were measured beat-to-beat and interpolated to 1~s intervals. HR and mBP were cross-correlated [CCF(HR-mBP)] during the PRBS. Eleven subjects participated in a reactive jump countermeasure (JUMP) during the BR period, the other part of the group served as control group (CTRL). RESULTS In the CTRL group, significantly lower CCF(HR-mBP) values during BDC-9 were observed compared to R + 2 during the lags 20-25~s and significantly higher values during the lags -~39~s to -~35~s. In the JUMP group, significantly lower CCFs were only observed at R + 2 compared with BDC-9 during the lags 23~s and 24~s, whereas the CCFs for BDC-9 were significantly higher at several lags compared with R + 13. CONCLUSION Attenuations in the regulation of the cardiovascular system during cycling exercise after BR were found in the CTRL group of the RSL study. Cardiovascular regulation in the JUMP group was improved compared to values before the beginning of BR, suggesting the effectiveness of the reactive jumps countermeasure to mitigate the deleterious effects of prolonged BR.},
      author = {Koschate, Jessica and Thiesch{\"a}fer, L. and Drescher, U. and Zieschang, T. and Hoffmann, U.},
      year = {2020},
      title = {Time-series analysis of heart rate and blood pressure in response to changes in work rate before and after 60 days of 6° head down tilt bed rest},
      journal = {European journal of applied physiology},
      doi = {10.1007/s00421-020-04576-2},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33427969} }
  • [article] bibtex
    C. Kowalski, P. Arizpe-Gomez, C. Fifelski, A. Brinkmann, und A. Hein, "Design of a Supportive Transfer Robot System for Caregivers to Reduce Physical Strain During Nursing Activities" Studies in Health Technology and Informatics, vol. 270, pp. 1245-1246, 2020.
    @article{Kowalski.2020c,
      author = {Kowalski, Christian and Arizpe-Gomez, Pedro and Fifelski, Conrad and Brinkmann, Anna and Hein, Andreas},
      year = {2020},
      title = {Design of a Supportive Transfer Robot System for Caregivers to Reduce Physical Strain During Nursing Activities},
      pages = {1245--1246},
      volume = {270},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics} }
  • [article] bibtex
    M. Lipprandt, A. Klausen, C. Alvarez-Castillo, S. Bosch, A. Weyland, und R. Röhrig, "Systematic failure analysis of critical incidents caused by kinked flow measurement cables from transport ventilators" ANASTHESIOLOGIE & INTENSIVMEDIZIN, vol. 61, pp. 76-84, 2020.
    @article{Lipprandt.2020,
      author = {Lipprandt, Myriam and Klausen, Andreas and Alvarez-Castillo, C. and Bosch, S. and Weyland, A. and R{\"o}hrig, Rainer},
      year = {2020},
      title = {Systematic failure analysis of critical incidents caused by kinked flow measurement cables from transport ventilators},
      pages = {76--84},
      volume = {61},
      issn = {0170-5334},
      journal = {ANASTHESIOLOGIE {\&} INTENSIVMEDIZIN} }
  • [article] bibtex
    J. S. Lubasch, B. Thumann, J. Bucksch, L. K. Brackmann, N. Wirsik, A. Donnelly, G. Hayes, K. Nimptsch, A. Steinbrecher, T. Pischon, J. Brug, W. Ahrens, und A. Hebestreit, "School- and Leisure Time Factors Are Associated With Sitting Time of German and Irish Children and Adolescents During School: Results of a DEDIPAC Feasibility Study" Frontiers in Sports and Active Living, vol. 2, p. 389, 2020.
    @article{Lubasch.2020,
      author = {Lubasch, Johanna Sophie and Thumann, Barbara and Bucksch, Jens and Brackmann, Lara Kim and Wirsik, Norman and Donnelly, Alan and Hayes, Grainne and Nimptsch, Katharina and Steinbrecher, Astrid and Pischon, Tobias and Brug, Johannes and Ahrens, Wolfgang and Hebestreit, Antje},
      year = {2020},
      title = {School- and Leisure Time Factors Are Associated With Sitting Time of German and Irish Children and Adolescents During School: Results of a DEDIPAC Feasibility Study},
      pages = {389},
      volume = {2},
      journal = {Frontiers in Sports and Active Living},
      doi = {10.3389/fspor.2020.00093} }
  • [article] bibtex
    S. March, S. Andrich, J. Drepper, D. Horenkamp-Sonntag, A. Icks, P. Ihle, J. Kieschke, B. Kollhorst, B. Maier, und I. Meyer, "Good Practice Data Linkage (GPD): A Translation of the German Version" International journal of environmental research and public health, vol. 17, iss. 21, p. 7852, 2020.
    @article{March.2020,
      author = {March, Stefanie and Andrich, Silke and Drepper, Johannes and Horenkamp-Sonntag, Dirk and Icks, Andrea and Ihle, Peter and Kieschke, Joachim and Kollhorst, Bianca and Maier, Birga and Meyer, Ingo},
      year = {2020},
      title = {Good Practice Data Linkage (GPD): A Translation of the German Version},
      pages = {7852},
      volume = {17},
      number = {21},
      journal = {International journal of environmental research and public health} }
  • [article] bibtex
    A. Pulst, A. M. Fassmer, F. Hoffmann, und G. Schmiemann, "Paramedics' Perspectives on the Hospital Transfers of Nursing Home Residents---A Qualitative Focus Group Study" International journal of environmental research and public health, vol. 17, iss. 11, p. 3778, 2020.
    @article{Pulst.2020b,
      author = {Pulst, Alexandra and Fassmer, Alexander Maximilian and Hoffmann, Falk and Schmiemann, Guido},
      year = {2020},
      title = {Paramedics' Perspectives on the Hospital Transfers of Nursing Home Residents---A Qualitative Focus Group Study},
      pages = {3778},
      volume = {17},
      number = {11},
      journal = {International journal of environmental research and public health} }
  • [article] bibtex
    A. C. Rahn, K. Riemann-Lorenz, A. Alegiani, G. E. A. Pust, A. van de Roemer, L. Schmitz, E. Vettorazzi, S. Köpke, und C. Heesen, "Comprehension of confidence intervals in audio-visual patient information materials for people with multiple sclerosis (COCO-MS): A web-based randomised controlled, parallel group trial" Patient education and counseling, 2020.
    @article{Rahn.2020, abstract = {OBJECTIVES To evaluate patient information materials on confidence intervals (CIs) in multiple sclerosis to be used with patient decision aids. METHODS Web-based randomised controlled parallel group trial with four study arms. Participants were equally allocated to one of three versions of audio-visual patient information or to a standard written information (arm IV). In the short version (arm III), CIs were explained without using an example, in the other two versions examples were used (arm I and arm II). The examples are based on an apple farmer who wants to estimate the average weight of his apples (arm I) and to test a treatment against worms (arm II). Primary endpoint was comprehension of CIs, assessed with a six-item multiple-choice questionnaire. RESULTS 855 of 1068 (80 {\%}) randomised participants completed the survey (71 {\%} arm I, 73 {\%} arm II, 87 {\%} arm III, 90 {\%} arm IV). The median of correctly answered questions on CIs was 4 out of 6 questions in arms I and II and 5 out of 6 questions in arm III. Compared to the standard information (arm IV), all the other arms scored better on the comprehension questionnaire (ANOVA, p $\leq$ 0.003). CONCLUSIONS Information about CIs can be presented comprehensibly. High scores and a high rate of completers indicate that the short version is the favourable one. PRACTICE IMPLICATIONS Information materials on CIs should be used alongside absolute risk reductions in patient decision aids to enhance the interpretation of study results.},
      author = {Rahn, Anne C. and Riemann-Lorenz, Karin and Alegiani, Anna and Pust, Gesa E. A. and {van de Roemer},
      Adrianus and Schmitz, Leonie and Vettorazzi, Eik and K{\"o}pke, Sascha and Heesen, Christoph},
      year = {2020},
      title = {Comprehension of confidence intervals in audio-visual patient information materials for people with multiple sclerosis (COCO-MS): A web-based randomised controlled, parallel group trial},
      journal = {Patient education and counseling},
      doi = {10.1016/j.pec.2020.09.035},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33054984} }
  • [article] bibtex
    Roeper J, Falk M, Chalaris-Rissmann A, A. Lueers, Wedeken K, Stropiep U, Tiemann M, Heukamp L, F. Otto-Sobotka, und F. Griesinger, "TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC" Oncotarget, vol. 11, iss. 3, pp. 250-264, 2020.
    @article{RoeperJ.2020,
      author = {{Roeper J} and {Falk M} and {Chalaris-Rissmann A} and Lueers, Andr{\'e} and {Wedeken K} and {Stropiep U} and {Tiemann M} and {Heukamp L} and Otto-Sobotka, F. and Griesinger, Frank},
      year = {2020},
      title = {TP53 co-mutations in EGFR mutated patients in NSCLC stage IV: A strong predictive factor of ORR, PFS and OS in EGFR mt+ NSCLC},
      pages = {250--264},
      volume = {11},
      number = {3},
      journal = {Oncotarget} }
  • [article] bibtex
    T. Rombey, K. Doni, F. Hoffmann, D. Pieper, und K. Allers, "More systematic reviews were registered in Prospero each year, but few records' status was up-to-date" Journal of Clinical Epidemiology, vol. 117, pp. 60-67, 2020.
    @article{Rombey.2020b,
      author = {Rombey, Tanja and Doni, Katharina and Hoffmann, Falk and Pieper, Dawid and Allers, Katharina},
      year = {2020},
      title = {More systematic reviews were registered in Prospero each year, but few records' status was up-to-date},
      pages = {60--67},
      volume = {117},
      issn = {0895-4356},
      journal = {Journal of Clinical Epidemiology} }
  • [article] bibtex
    N. Rösch, A. Münzberg, J. Sauer, M. Pirrung, S. Lämmel, S. Teichmann, M. Eichelberg, und A. Hein, "Comparison of app-based and paper-based diaries in food allergy diagnostics" Allergy, Meeting Abstract, Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), vol. 75, p. i, 2020.
    @article{Rosch.2020,
      author = {R{\"o}sch, Norbert and M{\"u}nzberg, Alexander and Sauer, Janina and Pirrung, Melissa and L{\"a}mmel, Sonja and Teichmann, Susanne and Eichelberg, Marco and Hein, Andreas},
      year = {2020},
      title = {Comparison of app-based and paper-based diaries in food allergy diagnostics},
      pages = {(in print)},
      volume = {75},
      journal = {Allergy, Meeting Abstract, Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI)},
      file = {Rösch et al. - 2020 - Comparison of app-based and paper-based diaries in food allergy diagnostics:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Rösch et al. - 2020 - Comparison of app-based and paper-based diaries in food allergy diagnostics.pdf:pdf} }
  • Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie, Deinzer, R. und von dem Knesebeck, O., Eds., Berlin: German Medical Science GMS Publishing House, 2020.
    @book{Deinzer.2020, year = {2020},
      title = {Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie},
      url = {https://books.publisso.de/en/publisso_gold/publishing/books/overview/46/155},
      address = {Berlin},
      urldate = {07.07.2020},
      publisher = {{German Medical Science GMS Publishing House}},
      editor = {Deinzer, Renate and {von dem Knesebeck},
      Olaf} }
  • [incollection] bibtex
    M. Schweda, "Altern" in Zeit im Lebensverlauf: Ein Glossar, Bielefeld: transcript, 2020, pp. 31-36.
    @incollection{Schweda.2020d,
      author = {Schweda, Mark},
      title = {Altern},
      pages = {31--36},
      publisher = {transcript},
      booktitle = {Zeit im Lebensverlauf: Ein Glossar},
      year = {2020},
      address = {Bielefeld} }
  • B. Engel und H. Prautzsch, Häufige Gichtanfälle und chronische Gicht: S2e-LeitlinieBerlin: , 2020.
    @misc{Engel.2020,
      author = {Engel, Bettina and Prautzsch, Horst},
      editor = {DEGAM},
      year = {2020},
      title = {H{\"a}ufige Gichtanf{\"a}lle und chronische Gicht: S2e-Leitlinie},
      url = {https://www.awmf.org/uploads/tx_szleitlinien/053-032al_S3_Haeufige-Gichtanfaelle-chronische-Gicht_2020-02.pdf},
      address = {Berlin},
      urldate = {16.2.21} }
  • [article] bibtex
    K. Allers, A. M. Fassmer, O. Spreckelsen, und F. Hoffmann, "End--of--life care of nursing home residents: A survey among general practitioners in northwestern Germany" Geriatrics & Gerontology International, vol. 20, iss. 1, pp. 25-30, 2020.
    @article{Allers.2020,
      author = {Allers, Katharina and Fassmer, Alexander Maximilian and Spreckelsen, Ove and Hoffmann, Falk},
      year = {2020},
      title = {End--of--life care of nursing home residents: A survey among general practitioners in northwestern Germany},
      pages = {25--30},
      volume = {20},
      number = {1},
      issn = {1444-1586},
      journal = {Geriatrics {\&} Gerontology International} }
  • [article] bibtex
    R. Diekmann, S. Hellmers, L. Elgert, S. Fudickar, A. Heinks, S. Lau, J. Bauer, T. Zieschang, und A. Hein, "Minimizing comprehensive geriatric assessment to identify deterioration of physical performance in a healthy community-dwelling older cohort: longitudinal data of the AEQUIPA Versa study" Aging Clinical and Experimental Research, 2020.
    @article{Diekmann.2020b, abstract = {It is important to identify the relevant parameters of physical performance to prevent early functional decline and to prolong independent living. The aim of this study is to describe the development of physical performance in a healthy community-dwelling older cohort aged 70+ years using comprehensive assessment over two years and to subsequently identify the most relevant predictive tests for physical decline to minimize assessment. Physical performance was measured by comprehensive geriatric assessment. Predictors for the individual decline of physical performance by Principal Component and k-means Cluster Analysis were developed, and sensitivity and specificity determined accordingly. 251 subjects ({\O} 75.4 years) participated in the study. Handgrip strength was low in 21.1{\%}. The follow-up results of tests were divergent. Handgrip strength [$-$ 16.95 (SD 11.55)] and the stair climb power test (power) [$-$ 9.15 (SD 16.84)] yielded the highest percentage changes. Four most relevant tests (handgrip strength, stair climb power time, timed up {\&} go and 4-m gait speed) were identified. A predictor based on baseline data was determined (sensitivity 82{\%},
      specificity 96{\%}) to identify subjects characterized by a high degree of physical decline within two years. Although the cohort of older adults is heterogeneous, most of the individuals in the study exhibited high levels of physical performance; only a few subjects suffered a relevant decline within the 2-year follow-up. Four most relevant tests were identified to predict relevant decline of physical function. In spite of ceiling effects of the geriatric assessment in high-performers, we assume that it is possible to predict an individual's risk of physical decline within 2 years with four tests of a comprehensive geriatric assessment.},
      author = {Diekmann, Rebecca and Hellmers, Sandra and Elgert, Lena and Fudickar, Sebastian and Heinks, Andrea and Lau, Sandra and Bauer, J{\"u}rgen and Zieschang, Tania and Hein, Andreas},
      year = {2020},
      title = {Minimizing comprehensive geriatric assessment to identify deterioration of physical performance in a healthy community-dwelling older cohort: longitudinal data of the AEQUIPA Versa study},
      issn = {1594-0667},
      journal = {Aging Clinical and Experimental Research},
      doi = {10.1007/s40520-020-01562-8},
      file = {Diekmann et al. - 2020 - Minimizing comprehensive geriatric assessment to identify deterioration of physical performance in a healthy co:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Diekmann et al. - 2020 - Minimizing comprehensive geriatric assessment to identify deterioration of physical performance in a healthy co.pdf:pdf} }
  • [article] bibtex
    N. Ellerich-Groppe, M. Schweda, und L. Pfaller, "#StayHomeForGrandma -- Towards an analysis of intergenerational solidarity and responsibility in the coronavirus pandemic" Social Sciences & Humanities Open, vol. 2, iss. 1, p. 100085, 2020.
    @article{EllerichGroppe.2020,
      author = {Ellerich-Groppe, Niklas and Schweda, Mark and Pfaller, Larissa},
      year = {2020},
      title = {{\#}StayHomeForGrandma -- Towards an analysis of intergenerational solidarity and responsibility in the coronavirus pandemic},
      pages = {100085},
      volume = {2},
      number = {1},
      journal = {Social Sciences {\&} Humanities Open},
      doi = {10.1016/j.ssaho.2020.100085} }
  • [article] bibtex
    A. M. Fassmer, A. Pulst, O. Spreckelsen, und F. Hoffmann, "Perspectives of general practitioners and nursing staff on acute hospital transfers of nursing home residents in Germany: results of two cross-sectional studies" BMC family practice, vol. 21, iss. 1, p. 29, 2020.
    @article{Fassmer.2020,
      author = {Fassmer, Alexander Maximilian and Pulst, Alexandra and Spreckelsen, Ove and Hoffmann, Falk},
      year = {2020},
      title = {Perspectives of general practitioners and nursing staff on acute hospital transfers of nursing home residents in Germany: results of two cross-sectional studies},
      pages = {29},
      volume = {21},
      number = {1},
      issn = {1471-2296},
      journal = {BMC family practice} }
  • [article] bibtex
    A. M. Fassmer und F. Hoffmann, "Acute health care services use among nursing home residents in Germany: a comparative analysis of out-of-hours medical care, emergency department visits and acute hospital admissions" Aging Clinical and Experimental Research, vol. 32, iss. 7, pp. 1359-1368, 2020.
    @article{Fassmer.2020d,
      author = {Fassmer, Alexander Maximilian and Hoffmann, Falk},
      year = {2020},
      title = {Acute health care services use among nursing home residents in Germany: a comparative analysis of out-of-hours medical care, emergency department visits and acute hospital admissions},
      pages = {1359--1368},
      volume = {32},
      number = {7},
      issn = {1594-0667},
      journal = {Aging Clinical and Experimental Research} }
  • [article] bibtex
    P. Gliesche, K. Seibert, C. Kowalski, D. Domhoff, M. Pfingsthorn, K. Wolf-Ostermann, und A. Hein, "Robotic Assistance in Nursing Care: Survey on Challenges and Scenarios" International Journal of Biomedical and Biological Engineering, vol. 14, iss. 9, pp. 257-262, 2020.
    @article{Gliesche.2020,
      author = {Gliesche, Pascal and Seibert, Kathrin and Kowalski, Christian and Domhoff, Dominik and Pfingsthorn, Max and Wolf-Ostermann, Karin and Hein, Andreas},
      year = {2020},
      title = {Robotic Assistance in Nursing Care: Survey on Challenges and Scenarios},
      pages = {257--262},
      volume = {14},
      number = {9},
      journal = {International Journal of Biomedical and Biological Engineering},
      file = {Gliesche et al. - 2020 - Robotic Assistance in Nursing Care Survey on Challenges and Scenarios:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gliesche et al. - 2020 - Robotic Assistance in Nursing Care Survey on Challenges and Scenarios.pdf:pdf} }
  • [article] bibtex
    F. Hoffmann, C. Bantel, und K. Jobski, "Agranulocytosis attributed to metamizole: An analysis of spontaneous reports in EudraVigilance 1985--2017" Basic & Clinical Pharmacology & Toxicology, vol. 126, iss. 2, pp. 116-125, 2020.
    @article{Hoffmann.2020d,
      author = {Hoffmann, Falk and Bantel, Carsten and Jobski, Kathrin},
      year = {2020},
      title = {Agranulocytosis attributed to metamizole: An analysis of spontaneous reports in EudraVigilance 1985--2017},
      pages = {116--125},
      volume = {126},
      number = {2},
      issn = {1742-7835},
      journal = {Basic {\&} Clinical Pharmacology {\&} Toxicology} }
  • K. Hower, T. Pförtner, P. Saak, A. Schneider, O. Aydin, H. Pfaff, J. Kons, S. E. Groß, und L. Ansmann, "Evaluation des FITKIDS-Programms zum gesunden Aufwachsen von Kindern aus suchtbelasteten Familien: Ergebnisse einer Interviewstudie mit suchterkrankten Eltern und deren Kindern" Suchttherapie, vol. 02, iss. 21, 2020.
    @article{Hower.2020b,
      author = {Hower, Kira and Pf{\"o}rtner, Timo-Kolja and Saak, Pamela and Schneider, Annika and Aydin, Osman and Pfaff, Holger and Kons, J{\"o}rg and Gro{\ss},
      Sophie Elisabeth and Ansmann, Lena},
      year = {2020},
      title = {Evaluation des FITKIDS-Programms zum gesunden Aufwachsen von Kindern aus suchtbelasteten Familien: Ergebnisse einer Interviewstudie mit suchterkrankten Eltern und deren Kindern},
      url = {https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1168-3676},
      volume = {02},
      number = {21},
      journal = {Suchttherapie},
      doi = {10.1055/a-1168-3676} }
  • [article] bibtex
    K. Jobski, F. Hoffmann, S. Herget-Rosenthal, und M. Dörks, "Drug interactions with oral anticoagulants in German nursing home residents: comparison between vitamin K antagonists and non-vitamin K antagonist oral anticoagulants based on two nested case--control studies" Clinical Research in Cardiology, vol. 109, iss. 4, pp. 465-475, 2020.
    @article{Jobski.2020b,
      author = {Jobski, Kathrin and Hoffmann, Falk and Herget-Rosenthal, Stefan and D{\"o}rks, Michael},
      year = {2020},
      title = {Drug interactions with oral anticoagulants in German nursing home residents: comparison between vitamin K antagonists and non-vitamin K antagonist oral anticoagulants based on two nested case--control studies},
      pages = {465--475},
      volume = {109},
      number = {4},
      issn = {1861-0692},
      journal = {Clinical Research in Cardiology} }
  • [article] bibtex
    S. Kapp, A. Herzberg, J. Czwikla, C. Schmelzer, F. Hoffmann, I. Nitschke, und H. Rothgang, "Verbesserung der Mundgesundheit bei Pflegebedürftigen in häuslicher Pflege: Welche weiteren Schritte sind notwendig?" Gesundheits-und Sozialpolitik, vol. 74, iss. 3, pp. 33-38, 2020.
    @article{Kapp.2020,
      author = {Kapp, Sonja and Herzberg, Alexandra and Czwikla, Jonas and Schmelzer, Cordula and Hoffmann, Falk and Nitschke, Ina and Rothgang, Heinz},
      year = {2020},
      title = {Verbesserung der Mundgesundheit bei Pflegebed{\"u}rftigen in h{\"a}uslicher Pflege: Welche weiteren Schritte sind notwendig?},
      pages = {33--38},
      volume = {74},
      number = {3},
      issn = {1611-5821},
      journal = {Gesundheits-und Sozialpolitik} }
  • [article] bibtex
    M. Klinkhammer-Schalke, T. Kaiser, C. Apfelbacher, S. Benz, K. E. Dreinhöfer, M. Geraedts, M. Hauptmann, F. Hoffmann, W. Hoffmann, und M. Koller, "Manual for Methods and Use of Routine Practice Data for Knowledge Generation" Das Gesundheitswesen, vol. 82, iss. 8-09, pp. 716-722, 2020.
    @article{KlinkhammerSchalke.2020,
      author = {Klinkhammer-Schalke, Monika and Kaiser, Thomas and Apfelbacher, Christian and Benz, Stefan and Dreinh{\"o}fer, Karsten E. and Geraedts, Max and Hauptmann, Michael and Hoffmann, Falk and Hoffmann, Wolfgang and Koller, Michael},
      year = {2020},
      title = {Manual for Methods and Use of Routine Practice Data for Knowledge Generation},
      pages = {716--722},
      volume = {82},
      number = {8-09},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen} }
  • [article] bibtex
    L. Martini, U. Maus, A. Bökel, V. Geng, Y. Kalke, T. Liebscher, N. Weidner, und F. Hoffmann, "Utilization of Outpatient Physical and Occupational Therapy in People With Spinal Cord Injury in Germany: Results of the German Spinal Cord Injury Survey" American Journal of Physical Medicine & Rehabilitation, vol. 99, iss. 6, pp. 532-539, 2020.
    @article{Martini.2020,
      author = {Martini, Luiza and Maus, Uwe and B{\"o}kel, Andrea and Geng, Veronika and Kalke, Yorck-Bernhard and Liebscher, Thomas and Weidner, Norbert and Hoffmann, Falk},
      year = {2020},
      title = {Utilization of Outpatient Physical and Occupational Therapy in People With Spinal Cord Injury in Germany: Results of the German Spinal Cord Injury Survey},
      pages = {532--539},
      volume = {99},
      number = {6},
      issn = {0894-9115},
      journal = {American Journal of Physical Medicine {\&} Rehabilitation} }
  • [article] bibtex
    A. Pulst, A. M. Fassmer, und G. Schmiemann, "Unplanned hospital transfers from nursing homes: who is involved in the transfer decision? Results from the HOMERN study" Aging Clinical and Experimental Research, 2020.
    @article{Pulst.2020, abstract = {BACKGROUND Emergency department visits and hospital admissions are common among nursing home residents (NHRs) and seem to be higher in Germany than in other countries. Yet, research on characteristics of transfers and involved persons in the transfer decision is scarce. AIMS The aim of this study was to analyze the characteristics of hospital transfers from nursing homes (NHs) focused on contacts to physicians, family members and legal guardians prior to a transfer. METHODS We conducted a multi-center study in 14 NHs in the regions Bremen and Lower Saxony (Northwestern Germany) between March 2018 and July 2019. Hospital transfers were documented for 12~months by nursing staff using a standardized questionnaire. Data were derived from care records and perspectives of nursing staff and were analyzed descriptively. RESULTS Among 802 included NHRs, n = 535 unplanned hospital transfers occurred of which 63.1{\%} resulted in an admission. Main reasons were deterioration of health status (e.g. fever, infections, dyspnea and exsiccosis) (35.1{\%}) and falls/accidents/injuries (33.5{\%}). Within 48~h prior to transfer, contact to at least one general practitioner (GP)/specialist/out-of-hour-care physician was 46.2{\%} and varied between the NHs (range: 32.3-83.3{\%}). GPs were involved in only 34.8{\%} of transfer decisions. Relatives and legal guardians were more often informed about transfer (62.3{\%} and 66.8{\%}) than involved in the decision (21.8{\%} and 15.1{\%}). DISCUSSION Contacts to physicians and involvement of the GP were low prior to unplanned transfers. The ranges between the NHs may be explained by organizational differences. CONCLUSION Improvements in communication between nursing staff, physicians and others are required to reduce potentially avoidable transfers.},
      author = {Pulst, Alexandra and Fassmer, Alexander Maximilian and Schmiemann, Guido},
      year = {2020},
      title = {Unplanned hospital transfers from nursing homes: who is involved in the transfer decision? Results from the HOMERN study},
      issn = {1594-0667},
      journal = {Aging Clinical and Experimental Research},
      doi = {10.1007/s40520-020-01751-5},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33258074} }
  • [article] bibtex
    A. Pulst, Fassmer, F. Hoffmann, und G. Schmiemann, "Vom Pflegeheim ins Krankenhaus--Erfahrungen und potenzielle Maßnahmen zur Reduktion der Transporte aus Sicht von Rettungskräften" Notfall+ Rettungsmedizin, vol. 23, iss. 8, pp. 575-577, 2020.
    @article{Pulst.2020d,
      author = {Pulst, A. and Fassmer and Hoffmann, F. and Schmiemann, G.},
      year = {2020},
      title = {Vom Pflegeheim ins Krankenhaus--Erfahrungen und potenzielle Ma{\ss}nahmen zur Reduktion der Transporte aus Sicht von Rettungskr{\"a}ften},
      pages = {575--577},
      volume = {23},
      number = {8},
      issn = {1436-0578},
      journal = {Notfall+ Rettungsmedizin} }
  • [article] bibtex
    I. Redeker, J. Callhoff, F. Hoffmann, J. Saam, H. Haibel, J. Sieper, A. Zink, und D. Poddubnyy, "Cost of illness in axial spondylarthritis for patients with and without tumor necrosis factor inhibitor treatment: results of a routine data analysis" Zeitschrift fur Rheumatologie, vol. 79, iss. 1, pp. 85-94, 2020.
    @article{Redeker.2020b,
      author = {Redeker, Imke and Callhoff, Johanna and Hoffmann, Falk and Saam, Joachim and Haibel, Hildrun and Sieper, Joachim and Zink, Angela and Poddubnyy, Denis},
      year = {2020},
      title = {Cost of illness in axial spondylarthritis for patients with and without tumor necrosis factor inhibitor treatment: results of a routine data analysis},
      pages = {85--94},
      volume = {79},
      number = {1},
      issn = {0340-1855},
      journal = {Zeitschrift fur Rheumatologie} }
  • [article] bibtex
    I. Redeker, J. Callhoff, F. Hoffmann, U. Marschall, H. Haibel, J. Sieper, A. Zink, und D. Poddubnyy, "The prevalence and impact of comorbidities on patients with axial spondyloarthritis: results from a nationwide population-based study" Arthritis research & therapy, vol. 22, iss. 1, p. 210, 2020.
    @article{Redeker.2020c,
      author = {Redeker, Imke and Callhoff, Johanna and Hoffmann, Falk and Marschall, Ursula and Haibel, Hildrun and Sieper, Joachim and Zink, Angela and Poddubnyy, Denis},
      year = {2020},
      title = {The prevalence and impact of comorbidities on patients with axial spondyloarthritis: results from a nationwide population-based study},
      pages = {210},
      volume = {22},
      number = {1},
      issn = {1478-6362},
      journal = {Arthritis research {\&} therapy} }
  • [article] bibtex
    T. Rombey, L. Puljak, K. Allers, J. Ruano, und D. Pieper, "Inconsistent views among systematic review authors towards publishing protocols as peer-reviewed articles: an international survey" Journal of Clinical Epidemiology, vol. S0895-4356, iss. 19, pp. 31023-31026, 2020.
    @article{Rombey.2020,
      author = {Rombey, Tanja and Puljak, Livia and Allers, Katharina and Ruano, Juan and Pieper, Dawid},
      year = {2020},
      title = {Inconsistent views among systematic review authors towards publishing protocols as peer-reviewed articles: an international survey},
      pages = {31023--31026},
      volume = {S0895-4356},
      number = {19},
      issn = {0895-4356},
      journal = {Journal of Clinical Epidemiology} }
  • [article] bibtex
    R. Schnakenberg, K. Silies, A. Berg, Ä. Kirchner, H. Langner, Y. Chuvayaran, J. Köberlein-Neu, B. Haastert, B. Wiese, und G. Meyer, "Study on advance care planning in care dependent community-dwelling older persons in Germany (STADPLAN): protocol of a cluster-randomised controlled trial" BMC Geriatrics, vol. 20, iss. 1, p. 142, 2020.
    @article{Schnakenberg.2020,
      author = {Schnakenberg, Rieke and Silies, Katharina and Berg, Almuth and Kirchner, {\"A}nne and Langner, Henriette and Chuvayaran, Yuliya and K{\"o}berlein-Neu, Juliane and Haastert, Burkhard and Wiese, Birgitt and Meyer, Gabriele},
      year = {2020},
      title = {Study on advance care planning in care dependent community-dwelling older persons in Germany (STADPLAN): protocol of a cluster-randomised controlled trial},
      pages = {142},
      volume = {20},
      number = {1},
      issn = {1471-2318},
      journal = {BMC Geriatrics} }
  • [article] bibtex
    N. Scholten, P. Ihle, und H. Pfaff, "Nachhaltige Infrastruktur für die Versorgungsforschung: Der Aufbau einer regionalen, krankenkassenübergreifenden GKV-Routinedatenbank" Das Gesundheitswesen, 2020.
    @article{Scholten.2020, abstract = {AIM The scientific use of SHI routine data is increasing, especially in the field of health services research. This also raises new questions with regard to the development of databases, which make it possible to store these data for longitudinal analyses over a longer period of time and by combining data from different SHI companies. On the basis of the experience gained in setting up the CoRe-Net database, we want to show that it is possible to install such a research infrastructure and make it usable in the long term. METHODOLOGY/RESULTS On the basis of the current regulatory framework (e. g. the added specification of {\S} 75 SGB X) and taking into account strict data protection criteria, it is possible to set up a database covering several health insurance funds: In CoRe-Net, a pseudonymisation centre and a trust centre were implemented for this purpose. At the same time, multiple pseudonymisation was carried out using a one-way hash procedure. Data analysis are only possible after approval by the participating health insurance funds and if valid approval has been obtained from relevant ethics committees. CONCLUSION The amendment of {\S} 75 SGB X in 2018 creates a legal framework for the collection and storage of SHI routine data within the framework of a research project for future questions within a defined research area. ZIEL: Die wissenschaftliche Nutzung von GKV Routinedaten hat v. a. auch im Bereich der Versorgungsforschung immer mehr zugenommen. Dadurch ergeben sich auch neue Fragen in Bezug auf den Aufbau von krankenkassen{\"u}bergreifenden Datenbanken, die eine l{\"a}ngerfristige Speicherung dieser Daten f{\"u}r l{\"a}ngsschnittliche Analysen m{\"o}glich machen sollen. Anhand der Erfahrungen beim Aufbau der CoRe-Net Datenbank soll gezeigt werden, dass es m{\"o}glich ist eine derartige Forschungsinfrastruktur zu installieren und langfristig nutzbar zu machen. METHODIK/ERGEBNISSE: Auf Basis der aktuellen geltenden Rahmenbedingungen (u. a. erg{\"a}nzte Pr{\"a}zisierung des {\S} 75 SGB X) und unter Ber{\"u}cksichtigung strenger datenschutzrechtlicher Kriterien ist es m{\"o}glich eine krankenkassen{\"u}bergreifende Datenbank aufzubauen: In CoRe-Net wurde dazu eine Pseudonymisierungs- und eine Vertrauensstelle implementiert. Gleichzeitig wird eine mehrfache Pseudonymisierung unter Nutzung eines Einweg-Hashverfahrens durchgef{\"u}hrt. Datenauswertungen sind nur nach Zustimmung durch die beteiligten Kassen und bei Vorliegen eines g{\"u}ltigen Ethikvotums m{\"o}glich. SCHLUSSFOLGERUNG: Die Anpassung des {\S} 75 SGB X in 2018 schaffte einen rechtlichen Rahmen, GKV-Routinedaten im Rahmen eines Forschungsvorhabens auch f{\"u}r k{\"u}nftige Fragestellungen im Rahmen eines definierten Forschungsbereichs zu erheben und zu speichern.},
      author = {Scholten, Nadine and Ihle, Peter and Pfaff, Holger},
      year = {2020},
      title = {Nachhaltige Infrastruktur f{\"u}r die Versorgungsforschung: Der Aufbau einer regionalen, krankenkassen{\"u}bergreifenden GKV-Routinedatenbank},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      doi = {10.1055/a-1205-0751},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33184806} }
  • [incollection] bibtex
    H. Haab, J. Alexandersson, J. Britz, R. Diekmann, M. Eichelberg, P. Elfert, A. Hein, J. Herrmann, L. Kuhn, S. Lämmel, A. Münzberg, N. Rösch, S. Roth, J. Sauer, S. Teichmann, J. Wojzischke, und D. Bieber, "Digitalisierte Dienstleitungen im Bereich der Ernährungsberatung von Personengruppen mit erhöhten gesundheitlichen Risiken bei Fehlernährung (DiDiER)" in Digitale Dienstleistungsinnovationen -- Transformationspfade und betriebliche Anwendungen, Beverungen, D., Stich, V., Schumann, J. H., und Strina, G., Eds., Springer Verlag, 2020, p. I.
    @incollection{Haab.2020,
      author = {Haab, Henning and Alexandersson, Jan and Britz, Jochen and Diekmann, Rebecca and Eichelberg, Marco and Elfert, Patrick and Hein, Andreas and Herrmann, Janna and Kuhn, Ludwig and L{\"a}mmel, Sonja and M{\"u}nzberg, Alexander and R{\"o}sch, Norbert and Roth, Susanne and Sauer, Janina and Teichmann, Susanne and Wojzischke, Julia and Bieber, Daniel},
      title = {Digitalisierte Dienstleitungen im Bereich der Ern{\"a}hrungsberatung von Personengruppen mit erh{\"o}hten gesundheitlichen Risiken bei Fehlern{\"a}hrung (DiDiER)},
      pages = {(IN PRINT)},
      publisher = {{Springer Verlag}},
      editor = {Beverungen, Daniel and Stich, Volker and Schumann, Jan H. and Strina, Giuseppe},
      booktitle = {Digitale Dienstleistungsinnovationen -- Transformationspfade und betriebliche Anwendungen},
      year = {2020},
      file = {Haab et al. - 2020 - Digitalisierte Dienstleitungen im Bereich der Ernährungsberatung von Personengruppen mit erhöhten gesundheitlichen:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Haab et al. - 2020 - Digitalisierte Dienstleitungen im Bereich der Ernährungsberatung von Personengruppen mit erhöhten gesundheitlichen.pdf:pdf} }
  • [incollection] bibtex
    M. Schweda, "The autumn of my years. Aging and the temporal structure of human life" in Ageing and Human Nature: Perspectives from Philosophical, Theological, and Historical Anthropology, Schweda, M., Coors, M., und Bozzaro, C., Eds., Cham: Springer, 2020, pp. 143-159.
    @incollection{Schweda.2020b,
      author = {Schweda, Mark},
      title = {The autumn of my years. Aging and the temporal structure of human life},
      pages = {143--159},
      publisher = {Springer},
      editor = {Schweda, Mark and Coors, Michael and Bozzaro, Claudia},
      booktitle = {Ageing and Human Nature: Perspectives from Philosophical, Theological, and Historical Anthropology},
      year = {2020},
      address = {Cham} }
  • [article] bibtex
    K. Emmerich, E. Müller-Simianer, H. Penner, und T. Zieschang, "Dysphagietherapie in der Geriatrie: Abwägungen zwischen Lebensqualität und Risiko -- eine qualitative Studie" Ethik in der Medizin, vol. 32, iss. 2, p. 293, 2020.
    @article{Emmerich.2020,
      author = {Emmerich, Katja and M{\"u}ller-Simianer, Elke and Penner, Heike and Zieschang, Tania},
      year = {2020},
      title = {Dysphagietherapie in der Geriatrie: Abw{\"a}gungen zwischen Lebensqualit{\"a}t und Risiko -- eine qualitative Studie},
      pages = {293},
      volume = {32},
      number = {2},
      issn = {0935-7335},
      journal = {Ethik in der Medizin},
      doi = {10.1007/s00481-020-00597-9} }
  • [article] bibtex
    U. Hoffmann, F. Möller, M. Haeger, F. Steinberg, N. Didkovskaya, E. Fomina, und J. Koschate, "LIVING 4 MONTHS IN CONFINEMENT AFFECTS CARDIORESPIRATORY REGULATIONS DURING EXERCISE - FIRST RESULTS FROM SIRIUS-19" Medicine & Science in Sports & Exercise, vol. 52, iss. 7S, p. 446, 2020.
    @article{Hoffmann.2020,
      author = {Hoffmann, Uwe and M{\"o}ller, Fabian and Haeger, Mathias and Steinberg, Fabian and Didkovskaya, Natalia and Fomina, Elena and Koschate, Jessica},
      year = {2020},
      title = {LIVING 4 MONTHS IN CONFINEMENT AFFECTS CARDIORESPIRATORY REGULATIONS DURING EXERCISE - FIRST RESULTS FROM SIRIUS-19},
      pages = {446},
      volume = {52},
      number = {7S},
      issn = {0195-9131},
      journal = {Medicine {\&} Science in Sports {\&} Exercise},
      doi = {10.1249/01.mss.0000678756.78882.59} }
  • M. Levelink, H. C. Eichstaedt, S. Meyer, und A. L. Brütt, "Living with a left ventricular assist device: psychological burden and coping: protocol for a cross-sectional and longitudinal qualitative study" BMJ open, vol. 10, iss. 10, p. 037017, 2020.
    @article{Levelink.2020b,
      author = {Levelink, M. and Eichstaedt, H. C. and Meyer, S. and Br{\"u}tt, Anna Levke},
      year = {2020},
      title = {Living with a left ventricular assist device: psychological burden and coping: protocol for a cross-sectional and longitudinal qualitative study},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/33087369},
      pages = {e037017},
      volume = {10},
      number = {10},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2020-037017} }
  • [article] bibtex
    I. Seeger, A. Klausen, S. Thate, F. Flake, O. Peters, W. Rempe, M. Peter, F. Scheinichen, U. Günther, R. Röhrig, und A. Weyland, "Gemeindenotfallsanitäter als innovatives Einsatzmittel in der Notfallversorgung -- erste Ergebnisse einer Beobachtungsstudie" NOTFALL & RETTUNGSMEDIZIN, vol. 155, iss. 2, p. 97, 2020.
    @article{Seeger.2020,
      author = {Seeger, Insa and Klausen, Andreas and Thate, S. and Flake, F. and Peters, O. and Rempe, W. and Peter, M. and Scheinichen, F. and G{\"u}nther, U. and R{\"o}hrig, Rainer and Weyland, A.},
      year = {2020},
      title = {Gemeindenotfallsanit{\"a}ter als innovatives Einsatzmittel in der Notfallversorgung -- erste Ergebnisse einer Beobachtungsstudie},
      pages = {97},
      volume = {155},
      number = {2},
      issn = {1434-6222},
      journal = {NOTFALL {\&} RETTUNGSMEDIZIN},
      doi = {10.1007/s10049-020-00715-6} }
  • N. Umbach, T. Beißbarth, A. Bleckmann, G. Duttge, L. Flatau, A. König, J. Kuhn, J. Perera-Bel, J. Roschauer, T. G. Schulze, M. Schweda, A. Urban, A. Zimmermann, und U. Sax, "Clinical application of genomic high-throughput data: Infrastructural, ethical, legal and psychosocial aspects" Eur Neuropsychopharmacol, vol. 31, pp. 1-15, 2020.
    @article{Umbach.2020,
      author = {Umbach, Nadine and Bei{\ss}barth, Tim and Bleckmann, Annalen and Duttge, Gunnar and Flatau, Laura and K{\"o}nig, Alexander and Kuhn, Jessica and Perera-Bel, Julia and Roschauer, Julia and Schulze, Thomas G. and Schweda, Mark and Urban, Alexander and Zimmermann, Anja and Sax, Ulrich},
      year = {2020},
      title = {Clinical application of genomic high-throughput data: Infrastructural, ethical, legal and psychosocial aspects},
      url = {http://www.sciencedirect.com/science/article/pii/S0924977X1930882X},
      pages = {1--15},
      volume = {31},
      issn = {0924-977x},
      journal = {Eur Neuropsychopharmacol},
      doi = {10.1016/j.euroneuro.2019.09.008} }
  • M. Voigt-Barbarowicz und A. L. Brütt, "The Agreement between Patients' and Healthcare Professionals' Assessment of Patients' Health Literacy-A Systematic Review" Int J Environ Res Public Health, vol. 17, iss. 7, 2020.
    @article{VoigtBarbarowicz.2020,
      author = {Voigt-Barbarowicz, M. and Br{\"u}tt, Anna Levke},
      year = {2020},
      title = {The Agreement between Patients' and Healthcare Professionals' Assessment of Patients' Health Literacy-A Systematic Review},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/32244459},
      volume = {17},
      number = {7},
      issn = {1661-7827 (Print) 1660-4601},
      journal = {Int J Environ Res Public Health},
      doi = {10.3390/ijerph17072372} }
  • [article] bibtex
    M. Weßel und C. Lang, "Rechtliche und Medizin-Ethische Fragen zur Freiwilligkeit der Kastration bei Sexualstraftätern" Medizinrecht, vol. 38, iss. 2, pp. 106-111, 2020.
    @article{Weel.2020,
      author = {We{\ss}el, Merle and Lang, Christina},
      year = {2020},
      title = {Rechtliche und Medizin-Ethische Fragen zur Freiwilligkeit der Kastration bei Sexualstraft{\"a}tern},
      pages = {106--111},
      volume = {38},
      number = {2},
      issn = {1433-8629},
      journal = {Medizinrecht},
      doi = {10.1007/s00350-020-5458-6} }
  • [incollection] bibtex | Dokument aufrufen Dokument aufrufen
    L. Ansmann und H. Pfaff, "3.3.4. Der Arzt als Mitglied eines Teams" in Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie, Deinzer, R. und von dem Knesebeck, O., Eds., Berlin: German Medical Science GMS Publishing House, 2020.
    @incollection{Ansmann.2020b,
      author = {Ansmann, Lena and Pfaff, H.},
      title = {3.3.4. Der Arzt als Mitglied eines Teams},
      url = {https://books.publisso.de/en/publisso_gold/publishing/books/overview/46/155},
      urldate = {07.07.2020},
      publisher = {{German Medical Science GMS Publishing House}},
      editor = {Deinzer, Renate and {von dem Knesebeck},
      Olaf},
      booktitle = {Online Lehrbuch der Medizinischen Psychologie und Medizinischen Soziologie},
      year = {2020},
      address = {Berlin} }
  • [incollection] bibtex
    L. Pfaller und M. Schweda, "(K)ein gutes Leben im Alter? Ethische Perspektiven auf Konzepte des Active Aging" in Gute Behandlung im Alter?, Frewer, A., Klotz, S., Herrler, C., und Bielefeldt, H., Eds., transcript Verlag, 2020, pp. 125-152.
    @incollection{Pfaller.2020,
      author = {Pfaller, Larissa and Schweda, Mark},
      title = {(K)ein gutes Leben im Alter? Ethische Perspektiven auf Konzepte des Active Aging},
      pages = {125--152},
      publisher = {{transcript Verlag}},
      isbn = {9783839451236},
      editor = {Frewer, Andreas and Klotz, Sabine and Herrler, Christoph and Bielefeldt, Heiner},
      booktitle = {Gute Behandlung im Alter?},
      year = {2020},
      doi = {10.14361/9783839451236-007} }
  • [inproceedings] bibtex
    P. Elfert, S. Siggelkow, M. Eichelberg, und A. Hein, "Towards an Ambient Survey of Consumption Quantities to Support the Nutrition Counselling Process for People affected by the Geriatric Frailty SyndromeTitle" in Proc. 25th IEEE Symposium on Computers and Communications (ISCC), 2020, p. i.
    @inproceedings{Elfert.2020b,
      author = {Elfert, Patrick and Siggelkow, Simon and Eichelberg, Marco and Hein, Andreas},
      title = {Towards an Ambient Survey of Consumption Quantities to Support the Nutrition Counselling Process for People affected by the Geriatric Frailty SyndromeTitle},
      keywords = {ambient sensor;nutrition diary;point cloud;stereoscopic camera},
      pages = {(in print)},
      publisher = {IEEE},
      isbn = {978-1-7281-8086-1},
      booktitle = {25th IEEE Symposium on Computers and Communications (ISCC)},
      year = {2020},
      file = {Elfert et al. - 2020 - No Towards an Ambient Survey of Consumption Quantities to Support the Nutrition Counselling Process for People af:C\:\\Users\\duwu2114\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Elfert et al. - 2020 - No Towards an Ambient Survey of Consumption Quantities to Support the Nutrition Counselling Process for People af.pdf:pdf} }
  • [inproceedings] bibtex
    S. Hellmers, L. Peng, S. Lau, R. Diekmann, L. Elgert, J. Bauer, A. Hein, und S. Fudickar, "Activity Scores of Older Adults based on Inertial Measurement Unit Data in Everyday Life" in Proc. Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 5: HEALTHINF, Valetta (Malta), 2020, pp. 579-585.
    @inproceedings{Hellmers.2020, abstract = {The trend of an ageing population is becoming more and more obvious. Staying healthy in old age is an important social issue. Thereby, physical activity is essential for the preservation of physical function. We developed an algorithm for determining the activity level of seniors in everyday life. The proposed algorithm is based on machine learning activity detection using inertial measurement unit data. A series of activity scores is obtained by executing the algorithm from data on the type of activity, total activity time and activity intensity. To evaluate the performance of the proposed algorithm, a study with 251 participants aged above 70 (75.41 $\pm$ 3.88) years was conducted and the correlation between individual activity scores and clinical mobility assessments was determined. Results showed a relation between the Six Minute Walking Test and the total score in terms of activity level as well as the walk score. Additionally, the MVPA- and walk-score show a clear trend regarding the frailty status of the participants. Therefore, these scores are indicators of the physical function and hence validate the utility of the developed algorithm.},
      author = {Hellmers, Sandra and Peng, Lianying and Lau, Sandra and Diekmann, Rebecca and Elgert, Lena and Bauer, J{\"u}rgen and Hein, Andreas and Fudickar, Sebastian},
      title = {Activity Scores of Older Adults based on Inertial Measurement Unit Data in Everyday Life},
      pages = {579--585},
      publisher = {{SCITEPRESS -- Science and Technology Publications, Lda}},
      booktitle = {Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies (BIOSTEC 2020) - Volume 5: HEALTHINF},
      year = {2020},
      address = {Valetta (Malta)},
      file = {Hellmers et al. - 2020 - Activity Scores of Older Adults based on Inertial Measurement Unit Data in Everyday Life:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2020 - Activity Scores of Older Adults based on Inertial Measurement Unit Data in Everyday Life.pdf:pdf} }
  • [article] bibtex
    A. C. Alegiani, A. C. Rahn, A. Steckelberg, G. Thomalla, C. Heesen, und S. Köpke, "Quality of Stroke Patient Information Applied in Randomized Controlled Trials-Literature Review" Frontiers in neurology, vol. 11, p. 526515, 2020.
    @article{Alegiani.2020, abstract = {Background: Strokes have a huge impact on patients' quality of life. Although there are potentially effective secondary preventions and treatment options for stroke patients, adherence is mostly low. Low disease and treatment-related knowledge and, consequently, a lack of informed decision-making in stroke patients may contribute to this problem. However, stroke patient information did not seem to have relevant effects on patients' knowledge in randomized controlled trials. One contributing factor may be the lack of thoroughly developed patient information materials. Methods: We aimed to evaluate the quality of patient information materials for stroke patients by using randomized controlled trials, applying quality criteria for evidence-based patient information (EBPI). We conducted a literature search (MEDLINE, Embase, CINAHL, PsycINFO, and CENTRAL). To be included in the review, research had to be randomized controlled trials that provided stroke patient information, were published in English, and had knowledge assessed as the primary endpoint. Authors of primary studies were contacted and asked for information materials applied. Results: We screened 15,507 hits and identified 30 eligible studies. Information materials were available for only eight studies. Analyses revealed that all available materials had important shortcomings concerning EBPI quality criteria [concerning, for example, structural information (e.g., reporting conflicts of interest), content information (e.g., reporting sources of information), or comprehensive descriptions of treatment effects and side effects]. Frequently, treatment effects were reported only narratively without providing absolute numbers, values, or frequencies. Conclusion: Quality of materials differed, but none sufficiently fulfilled EBPI quality criteria. Unsatisfactory trial results concerning patient knowledge and patient involvement in decision-making may at least partially be explained by limitations of the provided materials. Future patient information should consider EBPI quality criteria.},
      author = {Alegiani, Anna C. and Rahn, Anne C. and Steckelberg, Anke and Thomalla, G{\"o}tz and Heesen, Christoph and K{\"o}pke, Sascha},
      year = {2020},
      title = {Quality of Stroke Patient Information Applied in Randomized Controlled Trials-Literature Review},
      pages = {526515},
      volume = {11},
      issn = {1664-2295},
      journal = {Frontiers in neurology},
      doi = {10.3389/fneur.2020.526515},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750452},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33365010} }
  • [article] bibtex
    A. E. Althaus, U. Arendt, F. Hoffmann, J. Luske, M. H. Freitag, K. Jobski, und M. Dörks, "[Epistaxis and anticoagulation therapy: an analysis based on health insurance data from Lower Saxony]" HNO, 2020.
    @article{Althaus.2020, abstract = {BACKGROUND: Epistaxis is a common symptom in the medical practice. It is associated with various comorbidities and the use of medications, especially anticoagulants. Despite the high lifetime prevalence, there is limited data on prevalence and possible risk factors. METHODS: The study examines epistaxis care in a large patient population (AOK Lower Saxony) over a ten-year period (2007-2016). Risk factors, age at diagnosis, concomitant medication and comorbidities were analysed and the prevalence in the study period calculated. RESULTS: 162,167 patients visited their doctors between 2007-2016 (308,947 cases). Most patients were treated as outpatients (96.6{\%}) and 54{\%} of patients were men. Over the study period, the prevalence of epistaxis rose by 21{\%} (increase from 8.6 to 9.3 per 1000 insured persons per year) with a comparatively stable prevalence for the inpatient setting (0.2 per 1000 insured persons per year). In 54,105 of all epistaxis cases (17.5{\%}), the use of antithrombotic drugs was recorded (oral anticoagulants: 9.5{\%}). During the study period, increased prescribing of oral anticoagulants (from 7.7{\%} of cases in 2007 to 11.8{\%} in 2016), especially of NOAC was documented (from 0.1{\%} of cases in 2011 to 5.1{\%} in 2016). CONCLUSION: In addition to arterial hypertension, the predominant male sex and the typical age distribution, we found that cases of epistaxis often received anticoagulation therapy. This study showed an increase of epistaxis along with rising prescriptions of NOAC. In contrast, no increase of severe epistaxis cases leading to hospitalization was found.},
      author = {Althaus, A. E. and Arendt, U. and Hoffmann, Falk and Luske, J. and Freitag, Michael H. and Jobski, Kathrin and D{\"o}rks, Michael},
      year = {2020},
      title = {[Epistaxis and anticoagulation therapy: an analysis based on health insurance data from Lower Saxony]},
      keywords = {Anticoagulation;Epistaxis;Noac;Nosebleed;Prevalence},
      issn = {1433-0458 (Electronic) 0017-6192 (Linking)},
      journal = {HNO},
      originalyear = {Epistaxis und antithrombotische Medikation: eine Analyse der Daten einer gesetzlichen Krankenversicherung in Niedersachsen.},
      doi = {10.1007/s00106-020-00940-y},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32929520} }
  • [article] bibtex
    L. Ansmann, K. Hower, M. A. Wirtz, C. Kowalski, N. Ernstmann, L. McKee, und H. Pfaff, "Measuring social capital of healthcare organizations reported by employees for creating positive workplaces - validation of the SOCAPO-E instrument" BMC Health Services Research, vol. 20, iss. 1, p. 272, 2020.
    @article{Ansmann.2020c, abstract = {BACKGROUND In highly segmented and complex healthcare organizations social capital is assumed to be of high relevance for the coordination of tasks in healthcare. So far, comprehensively validated instruments on social capital in healthcare organizations are lacking. The aim of this work is to validate an instrument measuring social capital in healthcare organizations. METHODS This validation study is based on a cross-sectional survey of 1050 hospital employees from 49 German hospitals which specialize in breast cancer care. Social capital was assessed by a six-item scale. Reliability analyses and confirmatory factor analyses were conducted to determine the content validity of items within the theory-driven one-dimensional scale structure. The scale's associations with measures of the social aspects of the work environment (identification, social support, open communication climate) were estimated to test convergent validity. Criterion-related validity was evaluated by conducting structural equation modelling to examine the predictive validity of the scale with measures of work engagement, well-being and burnout. RESULTS A one-dimensional structure of the instrument could be identified (CFI = .99; RMSEA = .06). Convergent validity was shown by hypothesis-consistent correlations with social support offered by supervisors and colleagues, a climate of open communication, and employee commitment to the organization. Criterion-related validity of the social capital scale was proved by its prediction of employee work engagement (R2~= .10-.13 for the three subscales), well-being (R2~= .13), and burnout (R2~= .06-.11 for the three subscales). CONCLUSIONS The confirmed associations between social capital and work engagement, burnout as well as well-being stress the importance of social capital as a vital resource for employee health and performance in healthcare organizations. In healthcare organizations this short instrument can be used as an efficient instrument to measure the organizations' social capital.},
      author = {Ansmann, Lena and Hower, Kira and Wirtz, Markus Antonius and Kowalski, Christoph and Ernstmann, Nicole and McKee, Lorna and Pfaff, Holger},
      year = {2020},
      title = {Measuring social capital of healthcare organizations reported by employees for creating positive workplaces - validation of the SOCAPO-E instrument},
      pages = {272},
      volume = {20},
      number = {1},
      journal = {BMC Health Services Research},
      doi = {10.1186/s12913-020-05105-9},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32234055},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106807} }
  • [article] bibtex
    L. Ansmann und K. Hower, "Eine Frage der Organisation" SW Sozialwirtschaft, vol. 30, iss. 3, pp. 7-10, 2020.
    @article{Ansmann.2020d, abstract = {Die Bedeutung betrieblicher Verh{\"a}ltnisse f{\"u}r die gesundheitliche und soziale Versorgung wird oft untersch{\"a}tzt. Mit diesen Fragen, Ans{\"a}tzen und L{\"u}cken befasst sich die organisationsbezogene Versorgungsforschung. Prof. Dr. Lena Ansmann und Dr. Kira Hower stellen die noch junge Fachrichtung vor, erl{\"a}utern deren erste Ergebnisse und m{\"o}gliche Konsequenzen f{\"u}r die Patienten- und Nutzerorientierung im Gesundheitswesen und in der Sozialwirtschaft.},
      author = {Ansmann, Lena and Hower, Kira},
      year = {2020},
      title = {Eine Frage der Organisation},
      pages = {7--10},
      volume = {30},
      number = {3},
      issn = {1613-0707},
      journal = {SW Sozialwirtschaft},
      doi = {10.5771/1613-0707-2020-3-7} }
  • [article] bibtex
    T. Beltrame, M. O. Gois, U. Hoffmann, J. Koschate, R. L. Hughson, M. C. Moraes Frade, S. N. Linares, R. da Silva Torres, und A. M. Catai, "Relationship between maximal aerobic power with aerobic fitness as a function of signal-to-noise ratio" Journal of applied physiology (Bethesda, Md. : 1985), vol. 129, iss. 3, pp. 522-532, 2020.
    @article{Beltrame.2020, abstract = {Efforts to better understand cardiorespiratory health are relevant for the future development of optimized physical activity programs. We aimed to explore the impact of the signal quality on the expected associations between the ability of the aerobic system in supplying energy as fast as possible during moderate exercise transitions with its maximum capacity to supply energy during maximal exertion. It was hypothesized that a slower aerobic system response during moderate exercise transitions is associated with a lower maximal aerobic power; however, this relationship relies on the quality of the oxygen uptake data set. Forty-three apparently healthy participants performed a moderate constant work rate (CWR) followed by a pseudorandom binary sequence (PRBS) exercise protocol on a cycle ergometer. Participants also performed a maximum incremental cardiopulmonary exercise testing (CPET). The maximal aerobic power was evaluated by the peak oxygen uptake during the CPET, and the aerobic fitness was estimated from different approaches for oxygen uptake dynamics analysis during the CWR and PRBS protocols at different levels of signal-to-noise ratio. The product moment correlation coefficient was used to evaluate the correlation level between variables. Aerobic fitness was correlated with maximum aerobic power, but this correlation increased as a function of the signal-to-noise ratio. Aerobic fitness is related to maximal aerobic power; however, this association appeared to be highly dependent on the data quality and analysis for aerobic fitness evaluation. Our results show that simpler moderate exercise protocols might be as good as maximal exertion exercise protocols to obtain indexes related to cardiorespiratory health.NEW {\&} NOTEWORTHY Optimized methods for cardiorespiratory health evaluation are of great interest for public health. Moderate exercise protocols might be as good as maximum exertion exercise protocols to evaluate cardiorespiratory health. Pseudorandom or constant workload moderate exercise can be used to evaluate cardiorespiratory health.},
      author = {Beltrame, Thomas and Gois, Mariana Oliveira and Hoffmann, Uwe and Koschate, Jessica and Hughson, Richard Lee and {Moraes Frade},
      Maria Cec{\'i}lia and Linares, Stephanie Nogueira and {da Silva Torres},
      Ricardo and Catai, Aparecida Maria},
      year = {2020},
      title = {Relationship between maximal aerobic power with aerobic fitness as a function of signal-to-noise ratio},
      pages = {522--532},
      volume = {129},
      number = {3},
      journal = {Journal of applied physiology (Bethesda, Md. : 1985)},
      doi = {10.1152/japplphysiol.00310.2020},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32730176} }
  • [article] bibtex
    J. Bienzeisler, H. Fischer, V. Thiemann, und R. Röhrig, "Human-Induced Errors in Networked Healthcare Research: Risk Management Under the GDPR" Studies in Health Technology and Informatics, vol. 270, pp. 1128-1132, 2020.
    @article{Bienzeisler.2020, abstract = {Modern research projects in healthcare research and medical research are oftentimes multi-centered, multi-disciplinary, and conducted by a consortium of multiple collaborators. Increasingly, the resulting data emanating emerging from different primary and secondary sources is linked on a personal level. The General Data Protection Regulation regulates many fundamental processes in such research projects. Despite the regulatory framework given, it can happen that a collaborator does not handle data properly. We propose a systematic risk management for the handling of data as well as a systematic error management.},
      author = {Bienzeisler, Jonas and Fischer, Hauke and Thiemann, Volker and R{\"o}hrig, Rainer},
      year = {2020},
      title = {Human-Induced Errors in Networked Healthcare Research: Risk Management Under the GDPR},
      pages = {1128--1132},
      volume = {270},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      doi = {10.3233/SHTI200338},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32570557} }
  • [article] bibtex
    C. Breidenbach, R. Roth, L. Ansmann, S. Wesselmann, S. Dieng, E. Carl, G. Feick, A. Oesterle, P. Bach, B. Beyer, R. Borowitz, J. Erdmann, F. Kunath, S. Oostdam, I. Tsaur, F. Zengerling, und C. Kowalski, "Use of psycho-oncological services by prostate cancer patients: A multilevel analysis" Cancer medicine, vol. 9, iss. 11, pp. 3680-3690, 2020.
    @article{Breidenbach.2020, abstract = {BACKGROUND Cancer patients often suffer from psychological distress. Psycho-oncological services (POS) have been established in some health care systems in order to address such issues. This study aims to identify patient and center characteristics that elucidate the use of POS by patients in prostate cancer centers (PCCs). METHODS Center-reported certification and patient survey data from 3094 patients in 44 certified PCCs in Germany were gathered in the observational study (Prostate Cancer Outcomes). A multilevel analysis was conducted. RESULTS Model 1 showed that utilization of POS in PCCs is associated with patients' age (OR~=~0.98; 95{\%}-CI~=~0.96-0.99; P~{\textless}~.001), number of comorbidities (1-2 vs 0, OR~=~1.27; 95{\%}-CI~=~1.00-1.60; P=.048), disease staging (localized high-risk vs localized intermediate risk, OR~=~1.41; 95{\%}-CI~=~1.14-1.74; P~{\textless}~.001), receiving androgen deprivation therapy before study inclusion (OR~=~0.19; 95{\%}-CI~=~0.10-0.34; P~{\textless}~.001), and hospital teaching status (university vs academic, OR~=~0.09; 95{\%}-CI~=~0.02-0.55; P~=~.009). Model 2 additionally includes information on treatment after study inclusion and shows that after inclusion, patients who receive primary radiotherapy (OR~=~0.05; 95{\%}-CI~=~0.03-0.10; P~{\textless}~.001) or undergo active surveillance/watchful waiting (OR~=~0.06; 95{\%}-CI~=~0.02-0.15; P~{\textless}~.001) are less likely to utilize POS than patients who undergo radical prostatectomy. Disease staging (localized high-risk vs localized intermediate risk, OR~=~1.31; 95{\%}-CI~=~1.05-1.62; P~=~.02) and teaching status (university vs academic, OR~=~0.08; 95{\%}-CI~=~0.01-0.65; P~=~.02) are also significant predictors for POS use. The second model did not identify any other significant patient characteristics. CONCLUSIONS Future research should explore the role of institutional teaching status and whether associations with therapy after study inclusion are due to treatment effects - for example, less need following radiotherapy - or because access to POS is more difficult for those receiving radiotherapy.},
      author = {Breidenbach, Clara and Roth, Rebecca and Ansmann, Lena and Wesselmann, Simone and Dieng, Sebastian and Carl, Ernst-G{\"u}nther and Feick, G{\"u}nter and Oesterle, Alisa and Bach, Peter and Beyer, Burkhard and Borowitz, Rainer and Erdmann, J{\"o}rg and Kunath, Frank and Oostdam, Simba-Joshua and Tsaur, Igor and Zengerling, Friedemann and Kowalski, Christoph},
      year = {2020},
      title = {Use of psycho-oncological services by prostate cancer patients: A multilevel analysis},
      pages = {3680--3690},
      volume = {9},
      number = {11},
      journal = {Cancer medicine},
      doi = {10.1002/cam4.2999},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32233081},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286449} }
  • [article] bibtex
    A. Diekmann, C. Heuser, B. Schellenberger, B. Bohmeier, C. Holmberg, L. Ansmann, und N. Ernstmann, "Patient participation in multidisciplinary tumor conferences: Providers' perceptions of patients' need satisfaction and emotional experiences" Psycho-oncology, vol. 29, iss. 8, pp. 1263-1271, 2020.
    @article{Diekmann.2020, abstract = {OBJECTIVE In some breast and gynecological cancer centers in Germany, patients participate in multidisciplinary tumor conferences (MTCs) during the discussion of their own case. The aim of this study was to explore providers' perceptions concerning patients' emotional experiences during participation in an MTC by comparing the perspectives of providers with and without experience with patient participation. METHODS In this study, semi-structured interviews with n = 30 providers in n = 6 breast and gynecological cancer centers in North Rhine-Westphalia, Germany, were conducted. One half of the providers had no experience and the other half had experience with patient participation in MTCs. The interviews were audiotaped and transcribed, and content analysis was performed. RESULTS The results of this study show a mixed picture of met, unmet and disappointed needs of patients and their emotional reactions, which mainly overlap between both provider groups. Our results show that both provider groups report positive and negative experiences or expectations. CONCLUSION The mixed results regarding expected and perceived patient experiences from the providers' perspective suggest that patient participation in MTCs may not be exclusively of benefit. Further research on advantages and disadvantages for patients and on feasibility from the providers' perspective is necessary and will be conducted within the PINTU project.},
      author = {Diekmann, Annika and Heuser, Christian and Schellenberger, Barbara and Bohmeier, Barbara and Holmberg, Christine and Ansmann, Lena and Ernstmann, Nicole},
      year = {2020},
      title = {Patient participation in multidisciplinary tumor conferences: Providers' perceptions of patients' need satisfaction and emotional experiences},
      pages = {1263--1271},
      volume = {29},
      number = {8},
      journal = {Psycho-oncology},
      doi = {10.1002/pon.5413},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32419276} }
  • [article] bibtex
    F. Hoffmann und K. Allers, "[Hospitalization of nursing home residents in the last phase of life: an analysis of health insurance data]" Z Gerontol Geriatr, 2020.
    @article{Hoffmann.2020f, abstract = {BACKGROUND: Compared to the international literature a higher proportion of German nursing home residents (NHR) die in hospital. Data on longer periods before death and on regional differences are not available. OBJECTIVE: The frequency of hospitalizations of NHR in different periods during their last year of life were investigated. Differences between age, sex, level of nursing care, dementia and federal states were also assessed. MATERIAL AND METHODS: This study used data of a large German health insurance fund and included NHR aged 65+ years who died between 1 January 2010 and 31 December 2014. We assessed the proportion of NHR with at least one hospitalization during different periods before death. In-depth analyses were conducted for 0 (which corresponds to in-hospital death), 28 and 365 days before death. RESULTS: Of the 67,328 deceased residents (mean age: 85.3 years, 69.8{\%} female), 29.5{\%} died in hospital. A total of 51.5{\%} and 74.3{\%} were hospitalized during the last 28 and 365 days of life, respectively. These values were higher in the eastern parts of Germany. Males were hospitalized more often than women in all time periods. A higher care dependency was associated with fewer hospitalizations, especially shortly before death. There was no noticeable difference in the frequency of hospitalization between NHR with and without dementia. CONCLUSION: Approximately half of all NHR in Germany are hospitalized during the last month of life and one third die in hospital, which is relatively high compared to the international literature. No major differences were found between NHR with and without dementia, which is also contradictory to international studies. Overall, there is a need to optimize palliative care for NHR in Germany.},
      author = {Hoffmann, Falk and Allers, Katharina},
      year = {2020},
      title = {[Hospitalization of nursing home residents in the last phase of life: an analysis of health insurance data]},
      keywords = {End-of-life care;Health services research;Hospital use;Nursing homes;Sex differences},
      issn = {1435-1269 (Electronic) 0948-6704 (Linking)},
      journal = {Z Gerontol Geriatr},
      originalyear = {Krankenhausaufenthalte von Pflegeheimbewohnern in der letzten Lebensphase: eine Analyse von Krankenkassenroutinedaten.},
      doi = {10.1007/s00391-020-01716-3},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32185465} }
  • K. Hower, V. Vennedey, H. A. Hillen, S. Stock, L. Kuntz, H. Pfaff, T. Pförtner, I. Scholl, und L. Ansmann, "Is Organizational Communication Climate a Precondition for Patient-Centered Care? Insights from a Key Informant Survey of Various Health and Social Care Organizations" International journal of environmental research and public health, vol. 17, iss. 21, pp. 1-17, 2020.
    @article{Hower.2020,
      author = {Hower, Kira and Vennedey, Vera and Hillen, Hendrik Ansgar and Stock, Stephanie and Kuntz, Ludwig and Pfaff, H. and Pf{\"o}rtner, Timo-Kolja and Scholl, I. and Ansmann, Lena},
      year = {2020},
      title = {Is Organizational Communication Climate a Precondition for Patient-Centered Care? Insights from a Key Informant Survey of Various Health and Social Care Organizations},
      url = {https://www.mdpi.com/1660-4601/17/21/8074},
      urldate = {2.11.2020},
      pages = {1--17},
      volume = {17},
      number = {21},
      journal = {International journal of environmental research and public health},
      doi = {10.3390/ijerph17218074} }
  • [article] bibtex
    M. Kaspar, L. Liman, M. Ertl, G. Fette, L. K. Seidlmayer, L. Schreiber, F. Puppe, und S. Störk, "Unlocking the PACS DICOM Domain for its Use in Clinical Research Data Warehouses" Journal of digital imaging, vol. 33, iss. 4, pp. 1016-1025, 2020.
    @article{Kaspar.2020, abstract = {Clinical Data Warehouses (DWHs) are used to provide researchers with simplified access to pseudonymized and homogenized clinical routine data from multiple primary systems. Experience with the integration of imaging and metadata from picture archiving and communication systems (PACS), however, is rare. Our goal was therefore to analyze the viability of integrating a production PACS with a research DWH to enable DWH queries combining clinical and medical imaging metadata and to enable the DWH to display and download images ad hoc. We developed an application interface that enables to query the production PACS of a large hospital from a clinical research DWH containing pseudonymized data. We evaluated the performance of bulk extracting metadata from the PACS to the DWH and the performance of retrieving images ad hoc from the PACS for display and download within the DWH. We integrated the system into the query interface of our DWH and used it successfully in four use cases. The bulk extraction of imaging metadata required a median (quartiles) time of 0.09 (0.03-2.25) to 12.52 (4.11-37.30) seconds for a median (quartiles) number of 10 (3-29) to 103 (8-693) images per patient, depending on the extraction approach. The ad hoc image retrieval from the PACS required a median (quartiles) of 2.57 (2.57-2.79) seconds per image for the download, but 5.55 (4.91-6.06) seconds to display the first and 40.77 (38.60-41.63) seconds to display all images using the pure web-based viewer. A full integration of a production PACS with a research DWH is viable and enables various use cases in research. While the extraction of basic metadata from all images can be done with reasonable effort, the extraction of all metadata seems to be more appropriate for subgroups.},
      author = {Kaspar, Mathias and Liman, Leon and Ertl, Maximilian and Fette, Georg and Seidlmayer, Lea Katharina and Schreiber, Laura and Puppe, Frank and St{\"o}rk, Stefan},
      year = {2020},
      title = {Unlocking the PACS DICOM Domain for its Use in Clinical Research Data Warehouses},
      pages = {1016--1025},
      volume = {33},
      number = {4},
      journal = {Journal of digital imaging},
      doi = {10.1007/s10278-020-00334-0},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522145},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32314069} }
  • A. P. Lam, D. de Sordi, H. H. O. Müller, M. C. Lam, A. Carl, K. P. Kohse, und A. Philipsen, "Aggravation of symptom severity in adult attention-deficit/hyperactivity disorder by latent Toxoplasma gondii infection: a case-control study" Sci Rep, vol. 10, iss. 1, p. 14382, 2020.
    @article{Lam.2020,
      author = {Lam, A. P. and {de Sordi},
      D. and M{\"u}ller, H. H. O. and Lam, M. C. and Carl, A. and Kohse, K. P. and Philipsen, A.},
      year = {2020},
      title = {Aggravation of symptom severity in adult attention-deficit/hyperactivity disorder by latent Toxoplasma gondii infection: a case-control study},
      url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7463265/pdf/41598_2020_Article_71084.pdf},
      pages = {14382},
      volume = {10},
      number = {1},
      issn = {2045-2322},
      journal = {Sci Rep},
      doi = {10.1038/s41598-020-71084-w} }
  • [article] bibtex
    A. Pulst, A. M. Fassmer, F. Hoffmann, und G. Schmiemann, "Paramedics' Perspectives on the Hospital Transfers of Nursing Home Residents-A Qualitative Focus Group Study" Int J Environ Res Public Health, vol. 17, iss. 11, 2020.
    @article{Pulst.2020c, abstract = {Emergency department (ED) visits and hospital admissions are common among nursing home residents (NHRs). Little is known about the perspectives of emergency medical services (EMS) which are responsible for hospital transports. The aim of this study was to explore paramedics' experiences with transfers from nursing homes (NHs) and their ideas for possible interventions that can reduce transfers. We conducted three focus groups following a semi-structured question guide. The data were analyzed by content analysis using the software MAXQDA. In total, 18 paramedics (mean age: 33 years, male n = 14) participated in the study. Paramedics are faced with complex issues when transporting NHRs to hospital. They mainly reported on structural reasons (e.g., understaffing or lacking availability of physicians), which led to the initiation of an emergency call. Handovers were perceived as poorly organized because required transfer information (e.g., medication lists, advance directives (ADs)) were incomplete or nursing staff was insufficiently prepared. Hospital transfers were considered as (potentially) avoidable in case of urinary catheter complications, exsiccosis/infections and falls. Legal uncertainties among all involved professional groups (nurses, physicians, dispatchers, and paramedics) seemed to be a relevant trigger for hospital transfers. In paramedics' point of view, emergency standards in NHs, trainings for nursing staff, the improvement of working conditions and legal conditions can reduce potentially avoidable hospital transfers from NHs.},
      author = {Pulst, Alexandra and Fassmer, Alexander Maximilian and Hoffmann, Falk and Schmiemann, Guido},
      year = {2020},
      title = {Paramedics' Perspectives on the Hospital Transfers of Nursing Home Residents-A Qualitative Focus Group Study},
      volume = {17},
      number = {11},
      issn = {1661-7827 (Print) 1660-4601},
      journal = {Int J Environ Res Public Health},
      doi = {10.3390/ijerph17113778},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312002},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32466568} }
  • [article] bibtex
    I. Redeker, B. Siegmund, K. Ghoreschi, U. Pleyer, J. Callhoff, F. Hoffmann, U. Marschall, H. Haibel, J. Sieper, A. Zink, und D. Poddubnyy, "The impact of extra-musculoskeletal manifestations on disease activity, functional status, and treatment patterns in patients with axial spondyloarthritis: results from a nationwide population-based study" Therapeutic advances in musculoskeletal disease, vol. 12, p. 1759720, 2020.
    @article{Redeker.2020, abstract = {Objective The aim of this study was to investigate the association of extra-musculoskeletal manifestations (EMMs) with disease activity, functional status, and treatment patterns in a large population-based cohort of patients with axial spondyloarthritis (axSpA). Methods A stratified random sample of patients with axSpA, drawn from health insurance data, received a survey on disease-related characteristics including history (ever presence) of the following EMMs: inflammatory bowel disease (IBD), psoriasis (PSO), and anterior uveitis (AU). Survey data were linked to health insurance data, gathering additional information on current occurrence (within one year) of EMMs and drug prescriptions. Separate multivariable linear regression models were calculated to determine the association of EMMs with disease activity (Bath Ankylosing Spondylitis Disease Activity Index), and functional status (Bath Ankylosing Spondylitis Functional Index) after adjustment for relevant parameters, including treatment. Results A total of 1729 patients with axSpA were included in the analyses (response: 47{\%}; mean age: 56 years; 46{\%} female) of whom 6{\%} (9{\%}) had current (ever) IBD, 10{\%} (15{\%}) had current (ever) PSO, and 9{\%} (27{\%}) had current (ever) AU. Ever presence of IBD and history of PSO were significantly associated with higher level of disease activity. Ever presence of PSO was also associated with higher level of functional impairment, whereas current AU was significantly associated with lower disease activity. Patients with current IBD or PSO received more frequently biological and conventional synthetic disease-modifying anti-rheumatic drugs as well as systemic steroids. AU was associated with a higher use of conventional synthetic disease-modifying anti-rheumatic drugs only. Conclusion Disease activity is higher in patients with axSpA with history of IBD or history of PSO. Functional impairment is also higher in patients with axSpA with history of PSO. The presence of different EMMs was associated with different treatment patterns in axSpA.},
      author = {Redeker, Imke and Siegmund, Britta and Ghoreschi, Kamran and Pleyer, Uwe and Callhoff, Johanna and Hoffmann, Falk and Marschall, Ursula and Haibel, Hildrun and Sieper, Joachim and Zink, Angela and Poddubnyy, Denis},
      year = {2020},
      title = {The impact of extra-musculoskeletal manifestations on disease activity, functional status, and treatment patterns in patients with axial spondyloarthritis: results from a nationwide population-based study},
      pages = {1759720X20972610},
      volume = {12},
      issn = {1759-720X},
      journal = {Therapeutic advances in musculoskeletal disease},
      doi = {10.1177/1759720X20972610},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33281952},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682214} }
  • [article] bibtex
    S. Salm, K. Hower, S. Neumann, und L. Ansmann, "Validation of the German Version of the Transsexual Voice Questionnaire for Male-to-Female Transsexuals" Journal of voice : official journal of the Voice Foundation, vol. 34, iss. 1, pp. 68-77, 2020.
    @article{Salm.2020, abstract = {OBJECTIVE The purpose of this study was to examine the psychometric properties of the German translation of the Transsexual Voice Questionnaire for Male-to-Female Transsexuals (TVQMtF), an instrument assessing the voice-related quality of life (VrQoL) in trans women. STUDY DESIGN This is a cross-sectional study. METHOD The conducted online survey contained the TVQMtF as well as a generic measurement of VrQoL (Voice Handicap Index) and items on transition. Data of 127 trans women were analyzed computing coefficients of reliability and convergent validity. Additionally, confirmatory factor analysis and model modification were performed. RESULTS Analyses revealed excellent internal consistency (\textgreek{a} = 0.97), split-half reliability (rSB = 0.95) and good convergent validity. Significant associations were found between the total scores of the German TVQMtF and the Voice Handicap Index (r = 0.88; P {\textless} 0.001) as well as the vocal self-perception (r = -0.57; P {\textless} 0.001). An acceptable model with a two-factor structure including 22 of the 30 items was found. CONCLUSIONS The TVQMtF is the first German reliable and valid measurement of VrQoL for trans women. Therefore, its utilization can be recommended for clinical and research purposes in the fields of voice therapy and surgery.},
      author = {Salm, Sandra and Hower, Kira and Neumann, Sandra and Ansmann, Lena},
      year = {2020},
      title = {Validation of the German Version of the Transsexual Voice Questionnaire for Male-to-Female Transsexuals},
      pages = {68--77},
      volume = {34},
      number = {1},
      journal = {Journal of voice : official journal of the Voice Foundation},
      doi = {10.1016/j.jvoice.2018.06.010},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30172668} }
  • [article] bibtex
    V. Vennedey, K. Hower, H. A. Hillen, L. Ansmann, L. Kuntz, und S. Stock, "Patients' perspectives of facilitators and barriers to patient-centred care: insights from qualitative patient interviews" BMJ open, vol. 10, iss. 5, p. 033449, 2020.
    @article{Vennedey.2020, abstract = {OBJECTIVES Previous studies on patient-centred care (PCC) and its facilitators and barriers usually considered specific patient groups, healthcare settings and aspects of PCC or focused on expert perspectives. The objective of this study was to analyse patients' perspectives of facilitators and barriers towards implementing PCC. DESIGN We conducted semistructured individual interviews with chronically ill patients. The interviewees were encouraged to share positive and negative experiences of care and the related facilitators and barriers in all settings including preventive, acute and chronic health issues. Interview data were analysed based on the concept of content analysis. SETTING Interviews took place at the University Hospital Cologne, nursing homes, at participants' homes or by telephone. PARTICIPANTS Any person with at least one chronic illness living in the region of Cologne was eligible for participation. 25 persons with an average age of 60 years participated in the interviews. The participants suffered from various chronic conditions including mental health problems, oncological, metabolic, neurological diseases, but also shared experiences related to acute health issues. RESULTS Participants described facilitators and barriers of PCC on the microlevel (eg, patient-provider interaction), mesolevel (eg, health and social care organisation, HSCO) and macrolevel (eg, laws, financing). In addition to previous concepts, interviewees illustrated the importance of being an active patient by taking individual responsibility for health. Interviewees considered functioning teams and healthy staff members a facilitator of PCC as this can compensate stressful situations or lack of staff to some degree. A lack of transparency in financing and reimbursement was identified as barrier to PCC. CONCLUSION Individual providers and HSCOs can address many facilitators and barriers of PCC as perceived by patients. Large-scale changes such as reduction of administrative barriers, the expansion of care networks or higher mandatory nurse to patient ratios require political action and incentives. TRIAL REGISTRATION NUMBER DRKS00011925.},
      author = {Vennedey, Vera and Hower, Kira and Hillen, Hendrik Ansgar and Ansmann, Lena and Kuntz, Ludwig and Stock, Stephanie},
      year = {2020},
      title = {Patients' perspectives of facilitators and barriers to patient-centred care: insights from qualitative patient interviews},
      pages = {e033449},
      volume = {10},
      number = {5},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2019-033449},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7223019},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32376748} }
  • [article] bibtex
    R. Voltz, G. Dust, N. Schippel, S. Hamacher, S. Payne, N. Scholten, H. Pfaff, C. Rietz, und J. Strupp, "Improving regional care in the last year of life by setting up a pragmatic evidence-based Plan-Do-Study-Act cycle: results from a cross-sectional survey" BMJ open, vol. 10, iss. 11, p. 035988, 2020.
    @article{Voltz.2020, abstract = {OBJECTIVES To set up a pragmatic Plan-Do-Study-Act cycle by analysing patient experiences and determinants of satisfaction with care in the last year of life. DESIGN Cross-sectional postbereavement survey. SETTING Regional health services research and development structure representing all health and social care providers involved in the last year of life in Cologne, a city with 1 million inhabitants in Germany. PARTICIPANTS 351 bereaved relatives of adult decedents, representative for age and gender, accidental and suspicious deaths excluded. RESULTS For the majority (89{\%}) of patients, home was the main place of care during their last year of life. Nevertheless, 91{\%} of patients had at least one hospital admission and 42{\%} died in hospital. Only 60{\%} of informants reported that the decedent had been told that the disease was leading to death. Hospital physicians broke the news most often (58{\%}), with their communication style often (30{\%}) being rated as 'not sensitive'. Informants indicated highly positive experiences with care provided by hospices (89{\%} 'good') and specialist palliative home care teams (87{\%} 'good'). This proportion dropped to 41{\%} for acute care hospitals, this rating being determined by the feeling of not being treated with respect and dignity (OR=23.80, 95{\%} CI 7.503 to 75.498) and the impression that hospitals did not work well together with other services (OR=8.37, 95{\%} CI 2.141 to 32.71). CONCLUSIONS Following those data, our regional priority for action now is improvement of care in acute hospitals, with two new projects starting, first, how to recognise and communicate a limited life span, and second, how to improve care during the dying phase. Results and further improvement projects will be discussed in a working group with the city of Cologne, and repeating this survey in 2 years will be able to measure regional achievements. TRIAL REGISTRATION NUMBER DRKS00011925.},
      author = {Voltz, Raymond and Dust, Gloria and Schippel, Nicolas and Hamacher, Stefanie and Payne, Sheila and Scholten, Nadine and Pfaff, Holger and Rietz, Christian and Strupp, Julia},
      year = {2020},
      title = {Improving regional care in the last year of life by setting up a pragmatic evidence-based Plan-Do-Study-Act cycle: results from a cross-sectional survey},
      pages = {e035988},
      volume = {10},
      number = {11},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2019-035988},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689073},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33234614} }
  • [article] bibtex
    F. Wichmann, M. Braun, T. Ganz, J. S. Lubasch, T. Heidenreich, M. Laging, und C. R. Pischke, "Assessment of campus community readiness for tailoring implementation of evidence-based online programs to prevent risky substance use among university students in Germany" Translational behavioral medicine, vol. 10, iss. 1, pp. 114-122, 2020.
    @article{Wichmann.2020, abstract = {Research suggests that online interventions preventing risky substance use can improve student health. There is an increasing interest in transferring evidence-based online programs into university health promotion practice. However, little is known about how to best tailor the implementation process to capacities and context of individual universities. The purpose of this study was to assess the level of readiness (capacity) of German universities concerning the implementation of evidence-based online programs for risky substance use prevention employing an adapted Community Readiness Assessment (CRA) and to develop tailored action plans for implementation. The CRA involved 43 semi-structured interviews with key persons at 10 German universities. The interviews addressed five dimensions (knowledge of efforts, leadership, community climate, knowledge of the issue, and resources) at nine possible readiness stages (no awareness-ownership) and additional contextual factors. Overall, readiness for implementing online interventions across universities was rather low. Universities readiness levels ranged between the denial stage with a score of 2.1 and the preplanning stage with a score of 4.4. University-specific readiness was very heterogeneous. On the basis of the results of the CRA, universities received feedback and options for training on how to take the necessary steps to increase readiness and to prepare program implementation. The adapted version of the CRA was well suited to inform future implementation of evidence-based online programs for the prevention of risky substance use at participating universities.},
      author = {Wichmann, Frauke and Braun, Michael and Ganz, Thomas and Lubasch, Johanna Sophie and Heidenreich, Thomas and Laging, Marion and Pischke, Claudia R.},
      year = {2020},
      title = {Assessment of campus community readiness for tailoring implementation of evidence-based online programs to prevent risky substance use among university students in Germany},
      pages = {114--122},
      volume = {10},
      number = {1},
      journal = {Translational behavioral medicine},
      doi = {10.1093/tbm/ibz060},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31330011} }
  • [inproceedings] bibtex
    P. Elfert, S. Siggelkow, M. Eichelberg, und A. Hein, "Towards an Ambient Estimation of Stool Types to Support Nutrition Counseling for People affected by the Geriatric Frailty Syndrome" in Proc. 25th IEEE Symposium on Computers and Communications (ISCC), 2020, pp. 866-871.
    @inproceedings{Elfert.2020, abstract = {A person's stool can tell a lot about his or her state of health. Among other things, diarrhea or constipation lead to a reduced digestive efficiency. For many people their own stool is a shameful topic. However, the effectiveness of digestion of food has a direct influence on the recommendations for patients undergoing a nutritional therapy. This paper outlines a prototypical system for an automatic and ambient classification of stool forms into three classes: thin, normal, and hard stool based on the Bristol Stool Scale. The stool is recorded in transit after exiting the anus until it reaches the toilet floor to avoid the problems of conventional procedures. Corresponding data were generated under laboratory conditions. Various algorithms from the field of machine learning and deep learning were applied to this data. The evaluation results show that two out of five of these algorithms achieve classification rates of 100{\%}.},
      author = {Elfert, Patrick and Siggelkow, Simon and Eichelberg, Marco and Hein, Andreas},
      title = {Towards an Ambient Estimation of Stool Types to Support Nutrition Counseling for People affected by the Geriatric Frailty Syndrome},
      keywords = {ambient sensor;bristol stool scale;camera;deep learning;machine learning;point cloud;stereoscopic},
      pages = {866--871},
      publisher = {IEEE},
      isbn = {978-1-7281-8086-1},
      booktitle = {25th IEEE Symposium on Computers and Communications (ISCC)},
      year = {2020},
      file = {Elfert et al. - 2020 - Towards an Ambient Estimation of Stool Types to Support Nutrition Counseling for People affected by the Geriatric:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Elfert et al. - 2020 - Towards an Ambient Estimation of Stool Types to Support Nutrition Counseling for People affected by the Geriatric.pdf:pdf} }
  • [inproceedings] bibtex
    C. Lübbe, B. Friedrich, S. Fudickar, S. Hellmers, und A. Hein, "Feature Based Random Forest Nurse Care Activity Recognition Using Accelerometer Data" in Proc. Adjunct Proceedings of the 2020 ACM International Joint Conference on Pervasive and Ubiquitous Computing and Proceedings of the 2020 ACM International Symposium on Wearable Computers (UbiComp/ISWC '20 Adjunct), 2020.
    @inproceedings{Lubbe.2020, abstract = {The 2nd Nurse Care Activity Recognition Challenge Using Lab and Field Data addresses the important issue about care and the need for assistance systems in the nursing profession like automatic documentation systems. Data of 12 different care activities were recorded with an accelerometer attached to the right arm of the nurses. Both, laboratory and field data were taken into account. The task was to classify each activity based on the accelerometer data. We participated as team Gudetama in the challenge. We trained a Random Forest classifier and achieved an accuracy of 61.11{\%} on our internal test set.},
      author = {L{\"u}bbe, Carolin and Friedrich, Bj{\"o}rn and Fudickar, Sebastian and Hellmers, Sandra and Hein, Andreas},
      title = {Feature Based Random Forest Nurse Care Activity Recognition Using Accelerometer Data},
      keywords = {activity recognition;Classification;IMU;nurse activity recognition challenge;random forest;supervised learning;UNIAMT},
      publisher = {{ACM Press, New York, NY, USA}},
      isbn = {9781450380768},
      booktitle = {Adjunct Proceedings of the 2020 ACM International Joint Conference on Pervasive and Ubiquitous Computing and Proceedings of the 2020 ACM International Symposium on Wearable Computers (UbiComp/ISWC '20 Adjunct)},
      year = {2020},
      doi = {10.1145/3410530.3414340},
      file = {Lübbe et al. - 2020 - Feature Based Random Forest Nurse Care Activity Recognition Using Accelerometer Data:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lübbe et al. - 2020 - Feature Based Random Forest Nurse Care Activity Recognition Using Accelerometer Data.pdf:pdf} }
  • [article] bibtex
    L. Ansmann, A. Schabmann, S. E. Groß, A. Groß-Kunkel, U. Albert, und I. Osipov, "Are There Disparities in Surgical Treatment for Breast Cancer Patients with Prior Physical Disability A Path Analysis" Breast care (Basel, Switzerland), vol. 15, iss. 4, pp. 400-407, 2020.
    @article{Ansmann.2020, abstract = {Introduction Cancer care for patients with prior physical disability has hardly been researched in clinical research, health services research, or special education. This article aims to compare the severity of disease and the surgical treatment of diagnosed breast cancer patients with and without prior physical disability. Methods A total of 4,194 patients with primary breast cancer who underwent surgery in a breast cancer center in North Rhine-Westphalia, Germany, participated in an annual postoperative postal survey, which was complemented by clinical data. Latent class analysis and logit path models were applied to study (1) differences in terms of UICC staging and local cancer treatment between patients with and without prior physical disability and (2) respective differences by disability severity. Results Patients with physical disability (n = 780; 18.7{\%}) had a higher chance of receiving mastectomy compared to breast-conserving therapy, even after controlling for socioeconomic status and UICC staging. Disability severity is directly and indirectly associated with receiving a mastectomy. Conclusion In light of the research gap on disability and cancer, this work indicates disparities in care for breast cancer patients with prior physical disability. Inequalities might be attributable to (1) unequal access to care, (2) individual preferences and difficulties, or (3) medical difficulties.},
      author = {Ansmann, Lena and Schabmann, Alfred and Gro{\ss},
      Sophie Elisabeth and Gro{\ss}-Kunkel, Anke and Albert, Ute-Susann and Osipov, Igor},
      year = {2020},
      title = {Are There Disparities in Surgical Treatment for Breast Cancer Patients with Prior Physical Disability A Path Analysis},
      pages = {400--407},
      volume = {15},
      number = {4},
      issn = {1661-3791},
      journal = {Breast care (Basel, Switzerland)},
      doi = {10.1159/000503777},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32982651},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7490664} }
  • [article] bibtex
    K. Barteldrees, H. Pfaff, S. E. Groß, und L. Ansmann, "Gibt es einen Zusammenhang zwischen den Auditergebnissen und den Patientinnenerfahrungen in Brustzentren in Nordrhein-Westfalen?" Das Gesundheitswesen, vol. 82, iss. 8-09, pp. 691-701, 2020.
    @article{Barteldrees.2020, abstract = {AIM OF THE STUDY To ensure and improve the quality of care, patients with breast cancer in North Rhine-Westphalia are supposed to be treated in certified breast centres only. To obtain this certification, every 3 years all centres must undergo an auditing process. They also have to participate in an annual patient survey. While some studies have evaluated the benefit of certified centres regarding the quality of care offered, here we evaluate the relationship between the audit results and the experiences of patients. METHODS The quantitative results of the audit reports of 2014-2016 of breast centres in North Rhine-Westphalia were linked by multilevel analyses with different scales of the annual, post-operative, postal survey of primary breast cancer patients. RESULTS Audit reports and survey data on 3016 patients from 33 breast centres were examined and after adjusting for multiple testing, no statistically significant interrelation was found. CONCLUSION There are no associations between the results of a centre in the audit and the experiences of the patients. It appears that patients have a distinctive, subjective perception that cannot be represented by the audits alone, even though patient orientation is explicitly requested in the certification catalogue. This result underlines the benefit of the obligatory annual patient survey because it can provide information that apparently cannot be obtained from other sources, such as certification audits. CONCLUSION As a whole, an association between the audit results of a centre and the experiences of the patients treated there are weak. The audit results do correlate with the perceived process organization. However, other dimensions of patient experience are distinctive and subjective. Even though patient orientation is explicitly requested in the certification requirements, patient experience is not be represented by the audits alone. This finding underlines the benefit of obligatory annual patient surveys because they can provide additional information. ZIEL DER STUDIE In Nordrhein-Westfalen soll Brustkrebs zur Wahrung und Verbesserung der Versorgungsqualit{\"a}t nur in {\"A}Kzert-zertifizierten Brustzentren operiert werden. Daf{\"u}r m{\"u}ssen sich alle Zentren 3-j{\"a}hrlich einem Auditprozess unterziehen und j{\"a}hrlich an einer Patient*innenbefragung teilnehmen. W{\"a}hrend es zum Nutzen von zertifizierten Zentren bez{\"u}glich der Behandlungsqualit{\"a}t schon einige Studien gibt, soll nun untersucht werden, ob sich das Ergebnis des Auditierungsprozesses in den Erfahrungen der Patientinnen widerspiegelt. METHODIK Die quantitativen Ergebnisse aller Zertifizierungsauditberichte der Jahre 2014--2016 von Brustzentren in Nordrhein-Westfalen wurden mittels Mehrebenenanalysen mit verschiedenen Skalen einer j{\"a}hrlichen, poststation{\"a}ren, postalischen Befragung von Patient*innen mit prim{\"a}rem Mammakarzinom verkn{\"u}pft. ERGEBNISSE Es wurden Auditberichte und Befragungsdaten von 3016 Patientinnen aus 33 Brustzentren untersucht, dabei wurden nach Korrektur f{\"u}r multiples Testen keine statistisch signifikanten Zusammenh{\"a}nge gefunden. SCHLUSSFOLGERUNG Insgesamt zeigen sich keine Zusammenh{\"a}nge zwischen den Ergebnissen eines Zentrums im Audit und den Patientinnenerfahrungen. Die Patientinnen scheinen ein spezifisches subjektives Erleben zu haben, das trotz der ausdr{\"u}cklichen Forderung nach Patient*innenorientierung im Anforderungskatalog so nicht durch die Auditbesuche abgebildet werden kann. Das Ergebnis unterstreicht den Nutzen der j{\"a}hrlichen verpflichtenden Patient*innenbefragung, da sie weitergehende Informationen liefert, an die man durch andere Informationsquellen wie z. B. Zertifizierungsaudits offensichtlich nicht gelangt.},
      author = {Barteldrees, Kirsten and Pfaff, Holger and Gro{\ss},
      Sophie Elisabeth and Ansmann, Lena},
      year = {2020},
      title = {Gibt es einen Zusammenhang zwischen den Auditergebnissen und den Patientinnenerfahrungen in Brustzentren in Nordrhein-Westfalen?},
      pages = {691--701},
      volume = {82},
      number = {8-09},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      doi = {10.1055/a-0795-3388},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30625499} }
  • [article] bibtex
    A. Brinkmann, C. Fifelski, S. Lau, C. Kowalski, O. Meyer, R. Diekmann, M. Isken, S. Fudickar, und A. Hein, "The AAL/Care Laboratory -- A Healthcare Prevention System for Caregivers" Nanomaterials and Energy, vol. 9, iss. 1, pp. 1-10, 2020.
    @article{Brinkmann.2020,
      author = {Brinkmann, Anna and Fifelski, Conrad and Lau, Sandra and Kowalski, Christian and Meyer, Ole and Diekmann, Rebecca and Isken, Melvin and Fudickar, Sebastian and Hein, Andreas},
      year = {2020},
      title = {The AAL/Care Laboratory -- A Healthcare Prevention System for Caregivers},
      keywords = {biological;medical physics},
      pages = {1--10},
      volume = {9},
      number = {1},
      issn = {2045-9831},
      journal = {Nanomaterials and Energy},
      doi = {10.1680/jnaen.19.00021},
      file = {Brinkmann et al. - 2020 - The AALCare Laboratory – A Healthcare Prevention System for Caregivers:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Brinkmann et al. - 2020 - The AALCare Laboratory – A Healthcare Prevention System for Caregivers.pdf:pdf} }
  • A. Brinkmann, C. Fifelski, S. Lau, und C. Kowalski, "Quantification of Lower Limb and Spine Muscle Activity in Manual Patient Handling -- A Case Study" Studies in Health Technology and Informatics, vol. 272, pp. 249-252, 2020.
    @article{Brinkmann.2020b,
      author = {Brinkmann, Anna and Fifelski, Conrad and Lau, Sandra and Kowalski, Christian},
      year = {2020},
      title = {Quantification of Lower Limb and Spine Muscle Activity in Manual Patient Handling -- A Case Study},
      url = {http://ebooks.iospress.nl/volumearticle/54641},
      keywords = {health technology;healthcare workers;patient handling;sensors},
      pages = {249--252},
      volume = {272},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      doi = {10.3233/SHTI200541},
      file = {Brinkmann et al. - 2020 - Quantification of Lower Limb and Spine Muscle Activity in Manual Patient Handling – A Case Study:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Brinkmann et al. - 2020 - Quantification of Lower Limb and Spine Muscle Activity in Manual Patient Handling – A Case Study.pdf:pdf} }
  • B. Friedrich, E. Steen, H. Suwa, A. Hein, und K. Yasumoto, "Data Driven Analysis of the Behaviour of Elderly People Using k-Means and Home Automation and Power Consumption Sensors" International Journal of Computer Vision and Signal Processing, vol. 10, iss. 1, pp. 1-11, 2020.
    @article{Friedrich.2020, abstract = {Information about the mental and physical conditions of elderly people are essential to assess their ability to live alone in their own homes. Usually, those information are collected using questionnaires and geriatrics assessments. However, both methods have their limitations. People might not answer honestly to personal questions and geriatrics assessments are only measuring the capacity at a specific point in time. Moreover, questionnaires and assessments are limited in catching variability. Elderly people which have similar scores in questionnaires and assessment can still be very different in terms of mental and physical conditions. To get a distinguished impression of the condition long-term monitoring is needed. In this article we show that the behaviour of elderly people is so distinguished, that they can be identified by using k-Means clustering on a dataset comprised of motion sensor data and power consumption sensor data. Moreover, we show that the results of a combined dataset is different to considering each participant separately. We applied the algorithm to three participants of a real-world study. Even though two of the participants have similar questionnaire and assessment scores, they can be clearly distinguished from each other as well as from the third participant who has different scores. Contribution of the Paper: Showing the difference of elderly people with similar scores in standardised geriatrics assessments and questionnaires.},
      author = {Friedrich, Bj{\"o}rn and Steen, Enno-Edzard and Suwa, Hirohiko and Hein, Andreas and Yasumoto, Keiichi},
      year = {2020},
      title = {Data Driven Analysis of the Behaviour of Elderly People Using k-Means and Home Automation and Power Consumption Sensors},
      url = {http://cennser.org/IJCVSP/finalPaper/100103.pdf},
      keywords = {behaviour;comparison;elderly people;k-Means;UNIAMT},
      pages = {1--11},
      volume = {10},
      number = {1},
      journal = {International Journal of Computer Vision and Signal Processing},
      file = {Friedrich et al. - 2020 - Data Driven Analysis of the Behaviour of Elderly People Using k-Means and Home Automation and Power Consumptio:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Friedrich et al. - 2020 - Data Driven Analysis of the Behaviour of Elderly People Using k-Means and Home Automation and Power Consumptio.pdf:pdf} }
  • [article] bibtex
    S. Fudickar, S. Hellmers, S. Lau, R. Diekmann, J. Bauer, und A. Hein, "Measurement System for Unsupervised Standardized Assessment of Timed ``Up & Go'' and Five Times Sit to Stand Test in the Community---A Validity Study" Sensors, vol. 20, iss. 10, p. 2824, 2020.
    @article{Fudickar.2020, abstract = {Comprehensive and repetitive assessments are needed to detect physical changes in an older population to prevent functional decline at the earliest possible stage and to initiate preventive interventions. Established instruments like the Timed ``Up {\&} Go'' (TUG) Test and the Sit-to-Stand Test (SST) require a trained person (e.g., physiotherapist) to assess physical performance. More often, these tests are only applied to a selected group of persons already functionally impaired and not to those who are at potential risk of functional decline. The article introduces the Unsupervised Screening System (USS) for unsupervised self-assessments by older adults and evaluates its validity for the TUG and SST. The USS included ambient and wearable movement sensors to measure the user's test performance. Sensor datasets of the USS's light barriers and Inertial Measurement Units (IMU) were analyzed for 91 users aged 73 to 89 years compared to conventional stopwatch measurement. A significant correlation coefficient of 0.89 for the TUG test and of 0.73 for the SST were confirmed among USS's light barriers. Correspondingly, for the inertial data-based measures, a high and significant correlation of 0.78 for the TUG test and of 0.87 for SST were also found. The USS was a validated and reliable tool to assess TUG and SST.},
      author = {Fudickar, Sebastian and Hellmers, Sandra and Lau, Sandra and Diekmann, Rebecca and Bauer, J{\"u}rgen and Hein, Andreas},
      year = {2020},
      title = {Measurement System for Unsupervised Standardized Assessment of Timed ``Up {\&} Go'' and Five Times Sit to Stand Test in the Community---A Validity Study},
      keywords = {5xsst;Assessment;evaluation;five times sit-to-stand test;functional;go;Inertial;machine learning;measurement units;system usability;Technology;test;timed;tug;unsupervised;up;validity analysis},
      pages = {2824},
      volume = {20},
      number = {10},
      journal = {Sensors},
      doi = {10.3390/s20102824},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32429306},
      file = {Fudickar et al. - 2020 - Measurement System for Unsupervised Standardized Assessment of Timed “Up & Go” and Five Times Sit to Stand Test:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Fudickar et al. - 2020 - Measurement System for Unsupervised Standardized Assessment of Timed “Up & Go” and Five Times Sit to Stand Test.pdf:pdf} }
  • [article] bibtex
    S. Fudickar, R. Kappes, M. Horstmann, M. Isken, und A. Hein, "Cycling Monitoring System - Sensing Cycling Performance via a Pedal-Integrated IMU" Nanomaterials and Energy, vol. 9, iss. 1, pp. 1-6, 2020.
    @article{Fudickar.2020b, abstract = {With increasing accident rates for elderly cyclists when using electrically powered bicycles, behavioural models for cyclists that consider the underlying functional and cognitive processes are required. Such models must be generated based on experiments conducted in realistic driving conditions, since laboratory studies can cover the complex influences of cycling only to a limited degree. Consequently, this paper introduces a bicycle-monitoring system that was designed to capture all relevant external and internal states to be considered for the conduction of driving behavioural studies in realistic (uncontrolled) environments. Furthermore, algorithms for detecting the turning behaviour and the pedalling frequency by way of a pedal-integrated inertial measurement unit are introduced, and their sensitivity is evaluated in a pilot study.},
      author = {Fudickar, Sebastian and Kappes, Raphael and Horstmann, Marten and Isken, Melvin and Hein, Andreas},
      year = {2020},
      title = {Cycling Monitoring System - Sensing Cycling Performance via a Pedal-Integrated IMU},
      keywords = {processing;sensors;system},
      pages = {1--6},
      volume = {9},
      number = {1},
      issn = {2045-9831},
      journal = {Nanomaterials and Energy},
      doi = {10.1680/jnaen.19.00024} }
  • [article] bibtex
    C. Heuser, A. Diekmann, B. Schellenberger, B. Bohmeier, W. Kuhn, U. Karbach, N. Ernstmann, und L. Ansmann, "Patient Participation in Multidisciplinary Tumor Conferences from the Providers' Perspective: Is It Feasible in Routine Cancer Care?" Journal of multidisciplinary healthcare, vol. 13, pp. 1729-1739, 2020.
    @article{Heuser.2020, abstract = {Objective Recent studies from Germany show that a small amount of breast and gynecological cancer patients participate in multidisciplinary tumor conferences (MTCs) at some cancer centers. One reason for the variation by center might be the providers' attitudes about and experiences with MTC patient participation (MTCpp), which has not been analyzed before. Therefore, it is the aim of this study to analyze the providers' expected or experienced feasibility concerning MTCpp at breast and gynecological cancer centers in Germany. Methods This paper presents cross-sectional qualitative interview data from the PINTU study. From April to December 2018, n=30 health-care providers from n=6 breast and gynecological cancer centers in North-Rhine-Westphalia, Germany, were interviewed. One-half of the providers had no experience and the other half had experience with MTCpp. Inductive and deductive coding was performed in order to capture the feasibility aspects of participation. Results MTCpp seems not to be feasible in routine cancer care following providers' expected barriers and negative experiences. However, MTCpp seems to be feasible for selected cancer patients following providers' expected opportunities and positive experiences. Our results show that both provider groups report positive and negative experiences or expectations. Conclusion The mixed findings regarding expected or experienced feasibility of MTCpp provide first insights into differences concerning MTCpp between organizations. Our results suggest that the providers' perceptions (expectations and experiences) influence the possibility for patients to participate in an MTC in a cancer center.},
      author = {Heuser, Christian and Diekmann, Annika and Schellenberger, Barbara and Bohmeier, Barbara and Kuhn, Walther and Karbach, Ute and Ernstmann, Nicole and Ansmann, Lena},
      year = {2020},
      title = {Patient Participation in Multidisciplinary Tumor Conferences from the Providers' Perspective: Is It Feasible in Routine Cancer Care?},
      pages = {1729--1739},
      volume = {13},
      issn = {1178-2390},
      journal = {Journal of multidisciplinary healthcare},
      doi = {10.2147/JMDH.S283166},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708776},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33273821} }
  • [article] bibtex
    F. Hoffmann und K. Allers, "Ten-year trends in end-of-life hospitalizations of nursing home residents in Germany, 2006-2015" Maturitas, vol. 134, pp. 47-53, 2020.
    @article{Hoffmann.2020e, abstract = {OBJECTIVES: We investigated trends in end-of-life hospitalizations among nursing home residents (NHR) over 10 years and looked at differences between age groups and sexes as well as the length of terminal hospital stays. STUDY DESIGN: Retrospective cohort study based on health insurance claims data of the AOK Bremen/Bremerhaven. All NHR aged 65years or more who died between 2006 and 2015 were included. MAIN OUTCOME MEASURES: We assessed the proportions of decedents who were in hospital on the day of death and during the last 3, 7, 14 and 30 days of life, stratified by two-year periods. Multiple logistic regressions were conducted to study changes over time, adjusting for covariates. RESULTS: A total of 10,781 decedents were included (mean age 86.1 years, 72.1 {\%} females). Overall, 29.2 {\%} died in hospital, with a slight decrease from 30.3 {\%} in 2006-2007 to 28.3 {\%} in 2014-2015 (OR 0.86; 95 {\%} CI 0.75-0.98). Of the 3150 terminal hospitalizations, 35.5 {\%} lasted up to 3 days and the mean length of stay decreased from 9.0 (2006-2007) to 7.5 days (2014-2015). When looking at the last 7, 14 and 30 days of life, no changes over time were found. Male sex and younger age were associated with a higher chance of end-of-life hospitalization in almost all analyses. CONCLUSIONS: End-of-life hospitalizations of NHR are common in Germany. There has been a small decrease during recent years in the proportion of in-hospital deaths, but not of hospitalizations during the last 7, 14 and 30 days of life. This might be explained by shorter durations of hospital stays.},
      author = {Hoffmann, Falk and Allers, Katharina},
      year = {2020},
      title = {Ten-year trends in end-of-life hospitalizations of nursing home residents in Germany, 2006-2015},
      keywords = {*Length of Stay;Aged;Aged, 80 and over;End-of-life care;Female;Geriatrics/statistics {\&} numerical data/*trends;Germany/epidemiology;Health services research;Hospital use;Hospitals;Humans;Logistic Models;Long-term care;Male;Middle Aged;Nursing homes;Nursing Homes/statistics {\&} numerical data/*trends;Regression Analysis;Retrospective Studies;Terminal Care/statistics {\&} numerical data/*trends;Time Factors},
      pages = {47--53},
      volume = {134},
      issn = {0378-5122},
      journal = {Maturitas},
      doi = {10.1016/j.maturitas.2020.02.006},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32143776} }
  • [article] bibtex
    S. Kappen, L. Koops, V. Jürgens, M. H. Freitag, M. H. Blanker, A. Timmer, und G. H. de Bock, "General practitioners' approaches to prostate-specific antigen testing in the north-east of the Netherlands" BMC Fam Pract, vol. 21, iss. 1, p. 270, 2020.
    @article{Kappen.2020, abstract = {BACKGROUND There is wide variation in clinical practice for the early detection of prostate cancer, not least because of the ongoing debate about the benefits of prostate-specific antigen (PSA) testing. In this study, we aimed to assess the approaches, attitudes, and knowledge of general practitioners (GPs) regarding PSA testing in primary care in the Netherlands, particularly regarding recommendations for prostate cancer. METHODS Questionnaire surveys were sent to 179 GPs in the north-east of the Netherlands, of which 65 (36{\%}) were completed and returned. We also surveyed 23 GPs attending a postgraduate train-the-trainer day (100{\%}). In addition to demographic data and practice characteristics, the 31-item questionnaire covered the attitudes, clinical practice, adherence to PSA screening recommendations, and knowledge concerning the recommendations for prostate cancer early detection. Statistical analysis was limited to the descriptive level. RESULTS Most GPs (95{\%}; n~= 82) stated that they had at least read the Dutch GP guideline, but just half (50{\%}; n~= 43) also stated that they knew the content. Almost half (46{\%}; n~= 39) stated they would offer detailed counseling before ordering a PSA test to an asymptomatic man requesting a test. Overall, prostate cancer screening was reported to be of minor importance compared to other types of cancer screening. CONCLUSIONS Clinical PSA testing in primary care in this region of the Netherlands seems generally to be consistent with the relevant guideline for Dutch GPs that is restrictive to PSA testing. The next step will be to further evaluate the effects of the several PSA testing strategies.},
      author = {Kappen, Sanny and Koops, Lisa and J{\"u}rgens, Verena and Freitag, Michael H. and Blanker, Marco H. and Timmer, Antje and de Bock, Geertruida H.},
      year = {2020},
      title = {General practitioners' approaches to prostate-specific antigen testing in the north-east of the Netherlands},
      pages = {270},
      volume = {21},
      number = {1},
      issn = {1471-2296},
      journal = {BMC Fam Pract},
      doi = {10.1186/s12875-020-01350-3},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33334312},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747401} }
  • [article] bibtex
    I. Schiffmann, M. Freund, E. Vettorazzi, J. Stellmann, S. Heyer-Borchelt, M. D'Hooghe, V. Häußler, A. C. Rahn, und C. Heesen, "Assessing the effect of an evidence-based patient online educational tool for people with multiple sclerosis called UMIMS-understanding magnetic resonance imaging in multiple sclerosis: study protocol for a double-blind, randomized controlled trial" Trials, vol. 21, iss. 1, p. 1008, 2020.
    @article{Schiffmann.2020, abstract = {BACKGROUND While magnetic resonance imaging (MRI) plays a major role in the lives of people with multiple sclerosis (pwMS), studies have shown that MRI-specific knowledge in pwMS is limited. Moreover, poor knowledge was associated with negative feelings towards MRI (e.g. anxiety concerning MRI scan). Because information sources about MRI in MS for pwMS are not available, we designed and evaluated an evidence-based online educational platform about MRI in MS called {\textquotedbl}Understanding MRI in MS{\textquotedbl} (UMIMS). Based on a pilot study in n= 79 subjects, an educational intervention was found to be feasible and effective. We hypothesize that MRI-specific knowledge can be increased by using UMIMS and that, subsequently, negative feelings towards MRI will be reduced and shared decision-making competences increased. METHODS This randomized, controlled, double-blinded trial (RCT) will recruit n = 120 pwMS. The intervention group will receive access to UMIMS. The control group will get access to a specifically developed control website, which visually imitates UMIMS and contains the standard information available by several MS self-help organizations. The change in MRI-specific knowledge assessed via the MRI-risk knowledge questionnaire (MRI-RIKNO) after the intervention is the primary endpoint at 2 weeks. Several secondary endpoints will be assessed at different timepoints throughout the study, e.g. emotions towards MRI, autonomy preferences, threat by MS and shared decision-making competences. The study includes a process evaluation. DISCUSSION The aim of this RCT is to prove that access to an education tool on MRI in MS will increase pwMS' MRI-specific knowledge and enhance shared decision-making when discussing decisions involving MRI results during patient-physician encounters. TRIAL REGISTRATION Clinicaltrials.gov NCT03872583 . Registered on 13 March 2019.},
      author = {Schiffmann, Insa and Freund, Magalie and Vettorazzi, Eik and Stellmann, Jan-Patrick and Heyer-Borchelt, Susanne and D'Hooghe, Marie and H{\"a}u{\ss}ler, Vivien and Rahn, Anne Christin and Heesen, Christoph},
      year = {2020},
      title = {Assessing the effect of an evidence-based patient online educational tool for people with multiple sclerosis called UMIMS-understanding magnetic resonance imaging in multiple sclerosis: study protocol for a double-blind, randomized controlled trial},
      pages = {1008},
      volume = {21},
      number = {1},
      issn = {1745-6215},
      journal = {Trials},
      doi = {10.1186/s13063-020-04855-5.},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724874},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33298133} }
  • [article] bibtex
    A. K. Schröder, A. M. Fassmer, K. Allers, und F. Hoffmann, "Needs and availability of medical specialists' and allied health professionals' visits in German nursing homes: a cross-sectional study of nursing home staff" BMC Health Services Research, vol. 20, iss. 1, p. 332, 2020.
    @article{Schroder.2020, abstract = {BACKGROUND: The medical care for nursing home residents is estimated to be partly inadequate in Germany. The aim of this study is to investigate the needs and utilization of general practitioners (GPs), medical specialists and allied health professionals. METHODS: A survey was sent to a nationwide random sample of 1069 nursing homes in Germany in January 2019. Nursing staff managers were asked about medical care. Regular nursing home visits by medical specialists and allied health professionals were defined as at least one contact per year to at least one nursing home resident. RESULTS: A total of 486 persons responded (45.5{\%}). On average, nursing homes have contact to 8.6 (interquartile range: 4-10) different GPs. Almost 70{\%} of respondents agreed that residents' medical care should be coordinated by GPs. However, only 46.0{\%} stated that specialist treatment should require GP referral. A high need was seen for care from physiotherapists (91.0{\%}), neurologists or psychiatrists (89.3{\%}), dentists (73.7{\%}), and urologists (71.3{\%}). Regarding the actual utilization of medical specialists and health professionals, most nursing homes have regular contact to physiotherapists (97.1{\%}), psychiatrists or neurologists (90.4{\%}), speech therapists (85.0{\%}), and dentists (84.8{\%}). Remarkable discrepancies between need and utilization were found for urologists and ophthalmologists. CONCLUSION: There is large variance in the number of GPs per nursing home, and needs for medical specialists, especially urologists and ophthalmologists, seem unmet. Interprofessional collaboration between GPs, medical specialists and allied health professionals should be improved, and GPs should play a more coordinating role.},
      author = {Schr{\"o}der, A. K. and Fassmer, Alexander Maximilian and Allers, Katharina and Hoffmann, Falk},
      year = {2020},
      title = {Needs and availability of medical specialists' and allied health professionals' visits in German nursing homes: a cross-sectional study of nursing home staff},
      keywords = {*Allied Health Personnel;*Needs Assessment;*Nursing Homes/statistics {\&} numerical data;*Nursing Staff;*Specialization;Adult;Allied health professionals;Cross-Sectional Studies;Female;General Practitioners;Germany;Humans;Male;Medical specialists;Middle Aged;Needs;Nursing homes;Referral and Consultation;Skilled Nursing Facilities;survey;Surveys and Questionnaires},
      pages = {332},
      volume = {20},
      number = {1},
      journal = {BMC Health Services Research},
      doi = {10.1186/s12913-020-05169-7},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171863} }
  • [article] bibtex
    O. Spreckelsen, G. Schmiemann, M. H. Freitag, A. M. Fassmer, B. Engel, und F. Hoffmann, "Are there changes in medical specialist contacts after transition to a nursing home? an analysis of German claims data" BMC Health Services Research, vol. 20, iss. 1, p. 716, 2020.
    @article{Spreckelsen.2020, abstract = {BACKGROUND: Provision of ambulatory care by medical specialists for nursing home residents (NHR) is discussed to be inadequate in Germany, however with only incomplete evidence on this topic. We wanted to know whether the transition to a nursing home is associated with a general decrease in medical specialist care and therefore compared contact rates before and after institutionalization. METHODS: Claims data of 18,779 newly admitted NHR in 2013 were followed for the whole year prior to and up to two years after admission. The frequencies of contacts to specialists were assessed and stratified by sex, age, care level, dementia diagnosis and chronic conditions. Multivariate analyses were conducted to identify predictors for contacts to specialists. RESULTS: One year after institutionalization the most pronounced decrease was found in contacts with ophthalmologists (38.4{\%} vs. 30.6{\%}) whereas with most other specialties only small changes were found. The only specialty with a large increase were neurologists and psychiatrists (27.2{\%} vs. 43.0{\%}). Differences depending on sex and age were rather small while NHR with dementia or a higher care level had lower contact rates after institutionalization. Before institutionalization most patients were referred to a specialist by a general practitioner (61.7-73.9{\%}) while thereafter this proportion decreased substantially (27.8-58.6{\%}). The strongest predictor for a specialist contact after admission to a nursing home was a contact to a specialist before (OR 8.8, CI 7.96-9.72 for contacts to neurologists or psychiatrists). A higher nursing care level and a higher age were also predictors for specialist contacts. CONCLUSIONS: Relevant decreases of ambulatory specialist care utilization after institutionalization are restricted to ophthalmologists. NHR of higher age and higher nursing care level had a lower chance for a specialist contact. The assessment of the adequacy of the provided care after institutionalization remains inconclusive due to little investigated but assumable changes in care needs of NHR. The decreased coordination of care by general practitioners after institutionalization conflicts with health policy goals.},
      author = {Spreckelsen, Ove and Schmiemann, Guido and Freitag, Michael H. and Fassmer, Alexander Maximilian and Engel, Bettina and Hoffmann, Falk},
      year = {2020},
      title = {Are there changes in medical specialist contacts after transition to a nursing home? an analysis of German claims data},
      keywords = {Germany;Health services research;Nursing home residents;primary care;Secondary data analysis;specialist care},
      pages = {716},
      volume = {20},
      number = {1},
      journal = {BMC Health Services Research},
      doi = {10.1186/s12913-020-05575-x},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405335} }
  • [article] bibtex
    O. Spreckelsen, G. Schmiemann, A. M. Fassmer, B. Engel, F. Hoffmann, und M. H. Freitag, "How Do German General Practitioners Assess Medical Specialist Care Needs of Nursing Home Residents? Results of a Postal Survey in North-Western Germany" Int J Environ Res Public Health, vol. 17, iss. 19, 2020.
    @article{Spreckelsen.2020b, abstract = {The frequency of contacts of nursing home residents with medical specialists is lower compared to the general population of the same age group in Germany. The aim of this study was to assess general practitioners' (GPs) views on specialist care needs of nursing home residents, on questions of qualification and care coordination. A cross-sectional study was conducted with a postal questionnaire among a representative sample of 1121 GPs in north-western Germany in 2018. The perceptions of GPs about the relative importance of the type of specialist care that is required in nursing homes was assessed on a five-point Likert scale (0 = very low to 4 = very high). A total of 375 GPs (response 33.5{\%}; mean age 54.4 years; 57.6{\%} male) participated in the survey. GPs assessed care needs as highest for neurologists and psychiatrists (68.7{\%}) and lowest for gynecologists (6.5{\%}). Almost all respondents (96.2{\%}) strongly agreed that medical care for nursing home residents should be coordinated by GPs and that GPs should initiate the referral for further specialist care when required (87.5{\%}). A minority (25.7{\%}) agreed that quality of medical care would improve when care for a nursing home was provided by only one GP practice. GPs perceive the needs of nursing home residents for specialist care as high only in relation to care by neurologists and psychiatrists. GPs consider their own coordination function for medical care in nursing homes as very important.},
      author = {Spreckelsen, Ove and Schmiemann, Guido and Fassmer, Alexander Maximilian and Engel, Bettina and Hoffmann, Falk and Freitag, Michael H.},
      year = {2020},
      title = {How Do German General Practitioners Assess Medical Specialist Care Needs of Nursing Home Residents? Results of a Postal Survey in North-Western Germany},
      keywords = {coordination of care;Germany;Health services research;in the collection, analyses, or interpretation of data;in the writing;Nursing home residents;of the manuscript, or in the decision to publish the results.;of the study;primary care;specialist care;survey},
      volume = {17},
      number = {19},
      issn = {1661-7827 (Print) 1660-4601},
      journal = {Int J Environ Res Public Health},
      doi = {10.3390/ijerph17197126},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7579638} }
  • [article] bibtex
    E. Swart, H. Gothe, P. Ihle, S. March, I. Schubert, C. Stallmann, und F. Hoffmann, "Sonderheft Methodische Aspekte der Sekundärdatenanalyse" Das Gesundheitswesen, vol. 82, iss. S 02, p. s91-s93, 2020.
    @article{Swart.2020,
      author = {Swart, E. and Gothe, H. and Ihle, Peter and March, Stefanie and Schubert, I. and Stallmann, C. and Hoffmann, Falk},
      year = {2020},
      title = {Sonderheft Methodische Aspekte der Sekund{\"a}rdatenanalyse},
      keywords = {*Data Analysis;Germany},
      pages = {S91-s93},
      volume = {82},
      number = {S 02},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Sonderheft Methodische Aspekte der Sekund{\"a}rdatenanalyse.},
      doi = {10.1055/a-1099-0789} }
  • [article] bibtex
    E. Swart, H. Gothe, F. Hoffmann, P. Ihle, I. Schubert, C. Stallmann, und S. March, "[Aufbereitung und Validierung verschiedener Sekundärdatenquellen]" Das Gesundheitswesen, vol. 82, iss. S 01, p. s1-s3, 2020.
    @article{Swart.2020b,
      author = {Swart, E. and Gothe, H. and Hoffmann, Falk and Ihle, Peter and Schubert, I. and Stallmann, C. and March, Stefanie},
      year = {2020},
      title = {[Aufbereitung und Validierung verschiedener Sekund{\"a}rdatenquellen]},
      keywords = {*Data Analysis},
      pages = {S1-s3},
      volume = {82},
      number = {S 01},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Sonderheft Methodische Aspekte der Sekund{\"a}rdatenanalyse.},
      doi = {10.1055/a-1083-5461} }
  • [article] bibtex
    J. Wojzischke, J. van Wijngaarden, C. van den Berg, A. Cetinyurek-Yavuz, R. Diekmann, Y. Luiking, und J. Bauer, "Nutritional status and functionality in geriatric rehabilitation patients: a systematic review and meta-analysis" European geriatric medicine, vol. 11, iss. 2, pp. 195-207, 2020.
    @article{Wojzischke.2020, abstract = {PURPOSE Since there is only limited evidence available for geriatric rehabilitation patients, this systematic review and meta-analysis aims to characterize the nutritional status in this population and its relationship with functionality. METHODS Eight databases were searched for full-text articles reporting baseline nutritional intake and status of adults $\geq$ 60~years in rehabilitation settings. Pooled estimates were calculated for prevalence of malnutrition and risk of malnutrition based on the Mini~Nutritional Assessment (MNA) and for mean body mass index (BMI). Associations between nutritional status (MNA, MNA short form and BMI) and functional status (Barthel Index and Functional Independence Measure) and prevalence of sarcopenia were reviewed. RESULTS 62 out of 1717 references were eligible for inclusion. Pooled prevalence [95{\%} confidence interval (CI)] of malnutrition and risk of malnutrition were 13 (5-20) {\%} and 47 (40-54) {\%}. Pooled estimate (95{\%} CI) for BMI was 23.8 (23.2-24.5) kg/m2. Existing data suggest a risk for low protein and energy intake and vitamin D deficiency. Functional status differed widely. Seven out of ten studies reported significant associations between reduced nutritional status and reduced functionality, whilst two out of seven studies reported significant associations between higher BMI and functionality. Prevalence of sarcopenia was high with 40-76{\%} in this population. CONCLUSIONS Although geriatric rehabilitation populations and settings were heterogeneous, a relevant percentage of geriatric rehabilitation patients were affected by a reduced nutritional status. Nutritional status was associated with decreased functionality. This emphasizes the need for screening for malnutrition and targeted nutritional intervention.},
      author = {Wojzischke, Julia and {van Wijngaarden},
      Janneke and {van den Berg},
      Claudia and Cetinyurek-Yavuz, Aysun and Diekmann, Rebecca and Luiking, Yvette and Bauer, J{\"u}rgen},
      year = {2020},
      title = {Nutritional status and functionality in geriatric rehabilitation patients: a systematic review and meta-analysis},
      pages = {195--207},
      volume = {11},
      number = {2},
      issn = {1878-7649},
      journal = {European geriatric medicine},
      doi = {10.1007/s41999-020-00294-2},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32297199} }
  • [article] bibtex
    J. P. van Wijngaarden, J. Wojzischke, C. van den Berg, A. Cetinyurek-Yavuz, R. Diekmann, Y. C. Luiking, und J. M. Bauer, "Effects of Nutritional Interventions on Nutritional and Functional Outcomes in Geriatric Rehabilitation Patients: A Systematic Review and Meta-Analysis" J Am Med Dir Assoc, vol. 21, iss. 9, pp. 1207-1215.e9, 2020.
    @article{vanWijngaarden.2020, abstract = {OBJECTIVES It has been recognized that nutritional interventions play a role in improving the nutritional and functional status of older persons. This systematic review summarizes the evidence on nutritional and functional outcomes of nutritional interventions alone or in combination with physical exercise in geriatric rehabilitation patients. DESIGN Eight electronic databases were searched until July 1, 2019 to identify nutritional intervention studies in patients aged $\geq$60~years who were admitted to geriatric rehabilitation. A meta-analysis was performed to quantify intervention effects on serum albumin, muscle mass, and hand grip strength (HGS). RESULTS A total of 1962 studies were screened and 13 included in the systematic review. Studies were heterogeneous in interventions (4 nutritional interventions, 6 physical exercise~+~nutritional intervention, 1 timing of protein provision, 1 exercise~+~dietary advice, 1 nutrition-related nursing care) and outcomes. Among the 9 interventions that tested oral nutritional supplements (ONS) with protein, with or without exercise, 7 studies reported protein intake and 6 showed increased protein intakes, 2 of 5 studies showed increased albumin levels, and 5 of 9 reported an improvement in functional outcomes (BI, Functional Independence Measure, mobility). Meta-analyses showed no significant intervention effects on albumin [standardized mean difference (SMD) 0.45, 95{\%} confidence interval (CI)~-0.14, 1.04 (4 studies)], muscle mass [mean difference (MD) 2.14~kg, 95{\%} CI -2.17, 6.45 (3 studies)], and HGS [SMD -0.04, 95{\%} CI -0.55, 0.63 (3 studies)], but was based on a very limited number of studies. CONCLUSIONS AND IMPLICATIONS Only a limited number of studies with heterogeneous nutritional interventions and outcomes were available in the geriatric rehabilitation population. Studies that included ONS improved nutritional outcomes, especially protein intake and albumin levels. Functional outcomes improved in the majority of reporting studies. This indicates benefits of protein supplementation, with or without exercise, in this population. Future well-designed and well-powered clinical trials are needed to clarify existing controversial aspects.},
      author = {{van Wijngaarden},
      Janneke P. and Wojzischke, Julia and {van den Berg},
      Claudia and Cetinyurek-Yavuz, Aysun and Diekmann, Rebecca and Luiking, Yvette C. and Bauer, J{\"u}rgen M.},
      year = {2020},
      title = {Effects of Nutritional Interventions on Nutritional and Functional Outcomes in Geriatric Rehabilitation Patients: A Systematic Review and Meta-Analysis},
      pages = {1207-1215.e9},
      volume = {21},
      number = {9},
      issn = {1525-8610},
      journal = {J Am Med Dir Assoc},
      doi = {10.1016/j.jamda.2020.04.012},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/32723538} }
  • [inproceedings] bibtex
    B. Friedrich, C. Lübbe, und A. Hein, "Combining LSTM and CNN for Mode of Transportation Classification from Smartphone Sensors" in Proc. Adjunct Proceedings of the 2020 ACM International Joint Conference on Pervasive and Ubiquitous Computing and Proceedings of the 2020 ACM International Symposium on Wearable Computers (UbiComp/ISWC '20 Adjunct), 2020, p. 6.
    @inproceedings{Friedrich.2020c, abstract = {The broad availability of smartphones and Inertial Measurement Units in particular brings them into focus of recent research. Inertial Measurement Unit data is used for a variety of tasks. One important task is the classification of the mode of transportation. In this paper, we present a deep-learning-based algorithm, that combines long-short-term-memory (LSTM) layer and convolutional layer to classify eight different modes of transportation on the Sussex-Huawei Locomotion-Transportation (SHL) dataset. The inputs of our model are the accelerometer, gyroscope, linear acceleration, magnetometer, gravity and pressure values as well as the orientation information. We achieve a F1 score of 98.96{\%} on our private test set. We participated as team103114102106|8 in the Sussex-Huawei Locomotion-Transportation (SHL) recognition challenge.},
      author = {Friedrich, Bj{\"o}rn and L{\"u}bbe, Carolin and Hein, Andreas},
      title = {Combining LSTM and CNN for Mode of Transportation Classification from Smartphone Sensors},
      keywords = {Classification;convolutional neural networks;IMU;Mode of Transportation;SHL dataset;supervised learning;UNIAMT},
      pages = {6},
      publisher = {{ACM Press, New York, NY, USA}},
      isbn = {9781450380768},
      booktitle = {Adjunct Proceedings of the 2020 ACM International Joint Conference on Pervasive and Ubiquitous Computing and Proceedings of the 2020 ACM International Symposium on Wearable Computers (UbiComp/ISWC '20 Adjunct)},
      year = {2020},
      doi = {10.1145/3410530.3414350},
      file = {Friedrich, Lübbe, Hein - 2020 - Combining LSTM and CNN for Mode of Transportation Classification from Smartphone Sensors:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Friedrich, Lübbe, Hein - 2020 - Combining LSTM and CNN for Mode of Transportation Classification from Smartphone Sensors.pdf:pdf} }
  • [article] bibtex
    U. Günther, F. Hoffmann, O. Dewald, R. Malek, K. Brimmers, N. Theuerkauf, C. Putensen, und J. Popp, "Preoperative Cognitive Impairment and Postoperative Delirium Predict Decline in Activities of Daily Living after Cardiac Surgery-A Prospective, Observational Cohort Study" Geriatrics (Basel), vol. 5, iss. 4, p. 69, 2020.
    @article{Gunther.2020, abstract = {Cardiac surgery and subsequent treatment in the intensive care unit (ICU) has been shown to be associated with functional decline, especially in elderly patients. Due to the different assessment tools and assessment periods, it remains yet unclear what parameters determine unfavorable outcomes. This study sought to identify risk factors during the entire perioperative period and focused on the decline in activity of daily living (ADL) half a year after cardiac surgery. Follow-ups of 125 patients were available. It was found that in the majority of patients (60{\%}), the mean ADL declined by 4.9 points (95{\%} CI, -6.4 to -3.5; p {\textless} 0.000). In the {\textquotedbl}No decline{\textquotedbl} -group, the ADL rose by 3.3 points (2.0 to 4.6; p {\textless} 0.001). A multiple regression analysis revealed that preoperative cognitive impairment (MMSE {\textless}/= 26; Exp(B) 2.862 (95{\%}CI, 1.192-6.872); p = 0.019) and duration of postoperative delirium {\textgreater}/= 2 days (Exp(B) 3.534 (1.094-11.411); p = 0.035) was independently associated with ADL decline half a year after the operation and ICU. Of note, preoperative ADL per se was neither associated with baseline cognitive function nor a risk factor for functional decline. We conclude that the preoperative assessment of cognitive function, rather than functional assessments, should be part of risk stratification when planning complex cardiosurgical procedures.},
      author = {G{\"u}nther, U. and Hoffmann, Falk and Dewald, O. and Malek, R. and Brimmers, K. and Theuerkauf, N. and Putensen, C. and Popp, J.},
      year = {2020},
      title = {Preoperative Cognitive Impairment and Postoperative Delirium Predict Decline in Activities of Daily Living after Cardiac Surgery-A Prospective, Observational Cohort Study},
      keywords = {activity of daily living;cardiac;cognition;cognitive;delirium;intensive care;older people;outcomes;surgery},
      pages = {69},
      volume = {5},
      number = {4},
      issn = {2308-3417 (Electronic) 2308-3417 (Linking)},
      journal = {Geriatrics (Basel)},
      doi = {10.3390/geriatrics5040069},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/33022910} }
  • [article] bibtex
    K. Silies, R. Schnakenberg, A. Berg, Ä. Kirchner, H. Langner, J. Köberlein-Neu, G. Meyer, F. Hoffmann, und S. Köpke, "Process evaluation of a complex intervention to promote advance care planning in community-dwelling older persons (the STADPLAN study)-study protocol" Trials, vol. 21, iss. 1, p. 653, 2020.
    @article{Silies.2020, abstract = {BACKGROUND: Process evaluation addresses the implementation, mechanisms of impact, and context of participants in complex interventions. The STADPLAN study assesses the effects of conversations on advance care planning (ACP) led by trained nurse facilitators. The complex intervention consists of several components that may lead to various changes in attitude and behavior regarding personal ACP activities. With the process evaluation, we aim to assess how changes were achieved in the STADPLAN intervention. METHODS: The planned process evaluation study will be conducted alongside a cluster-randomized controlled trial on ACP in home care services (HCS). Trained nurse facilitators will deliver the ACP intervention consisting of an information brochure and two ACP conversations. A logic model depicts the assumed change processes of the intervention: the educational program enables nurses to conduct ACP conversations with patients and their caregivers. Patients gain knowledge and reflect upon and engage in their own ACP. Caregivers better understand patients' wishes and feel reassured in their role as surrogates. Designation of a surrogate and communication on ACP are facilitated. We will assess the effects of the educational program with questionnaires and a focus group including all participating nurses. We will measure ACP engagement, and prevalence of advance directives in patients, and ask for their experiences with the intervention. We will conduct semi-structured interviews with caregivers about their expectations and experiences regarding ACP in general and the intervention. We will address context factors, e.g., basic characteristics of the HCS (such as ownership, number of clients, staff and qualification). Analysis will be based upon the logic model, integrating qualitative and quantitative data. DISCUSSION: The comprehensive process evaluation will provide essential information on the feasibility of implementation strategies and the clinical relevance of a nurse-led ACP intervention in home care recipients and its generalizability and transferability to other settings. TRIAL REGISTRATION: German Clinical Trials Register: DRKS00016886 . Registered retrospectively on June 4, 2019, first participant included on May 29, 2019.},
      author = {Silies, Katharina and Schnakenberg, Rieke and Berg, Almuth and Kirchner, {\"A}nne and Langner, Henriette and K{\"o}berlein-Neu, Juliane and Meyer, Gabriele and Hoffmann, Falk and K{\"o}pke, Sascha},
      year = {2020},
      title = {Process evaluation of a complex intervention to promote advance care planning in community-dwelling older persons (the STADPLAN study)-study protocol},
      keywords = {Advance care planning;Ambulatory setting;Complex intervention;Home care setting;Logic model;Mixed methods;Nursing;Process evaluation;Study protocol},
      pages = {653},
      volume = {21},
      number = {1},
      issn = {1745-6215},
      journal = {Trials},
      doi = {10.1186/s13063-020-04529-2},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366302} }
  • [article] bibtex
    A. Strautmann, K. Allers, A. M. Fassmer, und F. Hoffmann, "Nursing home staff's perspective on end-of-life care of German nursing home residents: a cross-sectional survey" BMC Palliat Care, vol. 19, iss. 1, p. 2, 2020.
    @article{Strautmann.2020, abstract = {BACKGROUND: Nursing homes are becoming more important for end-of-life care. Within the industrialised world, Germany is among the countries with the most end-of-life hospitalizations in nursing home residents. To improve end-of-life care, investigation in the status quo is required. The objective was to gain a better understanding of the perspectives of nursing home staff on the current situation of end-of-life care in Germany. METHODS: A cross-sectional study was conducted as a postal survey among a random sample of 1069 German nursing homes in 2019. The survey was primarily addressed to nursing staff management. Data was analyzed using descriptive statistics. Staff was asked to rate different items regarding common practices and potential deficits of end-of-life care on a 5-point-Likert-scale. Estimations of the proportions of in-hospital deaths, residents with advance directives (AD), cases in which documented ADs were ignored, and most important measures for improvement of end-of-life care were requested. RESULTS: 486 (45.5{\%}) questionnaires were returned, mostly by nursing staff managers (64.7{\%}) and nursing home directors (29.9{\%}). 64.4{\%} of the respondents rated end-of-life care rather good, the remainder rated it as rather bad. The prevalence of in-hospital death was estimated by the respondents at 31.5{\%} (SD: 19.9). Approximately a third suggested that residents receive hospital treatments too frequently. Respondents estimated that 45.9{\%} (SD: 21.6) of the residents held ADs and that 28.4{\%} (SD: 26.8) of available ADs are not being considered. Increased staffing, better qualification, closer involvement of general practitioners and better availability of palliative care concepts were the most important measures for improvement. CONCLUSIONS: Together with higher staffing, better availability and integration of palliative care concepts may well improve end-of-life care. Prerequisite for stronger ties between nursing home and palliative care is high-quality education of those involved in end-of-life care.},
      author = {Strautmann, A. and Allers, Katharina and Fassmer, Alexander Maximilian and Hoffmann, Falk},
      year = {2020},
      title = {Nursing home staff's perspective on end-of-life care of German nursing home residents: a cross-sectional survey},
      keywords = {Adult;Cross-Sectional Studies;End-of-life care;Female;Germany;Health Personnel/*psychology;Humans;Male;Middle Aged;Nursing home residents;Nursing Homes/organization {\&} administration/standards/statistics {\&} numerical data;Nursing staff;survey;Terminal Care/*methods/psychology/standards},
      pages = {2},
      volume = {19},
      number = {1},
      issn = {1472-684x},
      journal = {BMC Palliat Care},
      doi = {10.1186/s12904-019-0512-8},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942381} }
  • [article] bibtex
    J. Tillmann, R. Schnakenberg, K. Weckbecker, J. M. Just, B. Weltermann, und E. Münster, "[Addressing Issues of Living Will and Power of Attorney in Patients With Dementia - A Cross-Sectional Study Among German General Practitioners]" Das Gesundheitswesen, vol. 82, iss. 2, pp. 188-195, 2020.
    @article{Tillmann.2020, abstract = {OBJECTIVES: Issues of living will and power of attorney must be addressed as early as possible in dementia patients because of their decreasing independence and ability to act for themselves. The aim of this study was to investigate whether general practitioners (GPs), who usually have long-standing and regular contact with this group of patients, address these precautionary measures and if there is any association between this approach and further communication and educational behaviour of doctors. METHODS: A cross-sectional survey, using standardized, written questionnaires, was conducted in a random sample of 982 GPs in North Rhine-Westphalia in western Germany between October 2017 and January 2018. Descriptive statistical as well as logistic regression analyses were carried out using IBM SPSS Statistics, version 24. RESULTS: A total of 339 GPs responded to the survey questionnaire (response rate: 34.5{\%}). A majority of GPs (70.1{\%}) agreed totally or partially that it was necessary to address their dementia patients on living will and power of attorney; GPs who were more confident in communicating a dementia diagnosis reported addressing the issue of documents for the end of life more frequently (aOR: 1.97; 95{\%}-CI: 1.17-3.33). Older GPs with greater knowledge of regional services for dementia patients also tended to address this topic more frequently. CONCLUSIONS: General practitioners make a major contribution to help dementia patients and their relatives to plan ahead at an early stage of the disease. It can be concluded from our results that GPs' knowledge and experiences about dementia and local services, as well as how to deal with those affected should be improved in order to optimise communication on living will and power of attorney as precautionary measures.},
      author = {Tillmann, J. and Schnakenberg, Rieke and Weckbecker, Klaus and Just, J. M. and Weltermann, B. and M{\"u}nster, E.},
      year = {2020},
      title = {[Addressing Issues of Living Will and Power of Attorney in Patients With Dementia - A Cross-Sectional Study Among German General Practitioners]},
      keywords = {*Dementia;*General Practitioners;*Living Wills;*Proxy;Attitude of Health Personnel;Cross-Sectional Studies;Germany;Humans;Surveys and Questionnaires},
      pages = {188--195},
      volume = {82},
      number = {2},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Haus{\"a}rztlicher Umgang mit Patientenverf{\"u}gung und Vorsorgevollmacht bei Demenzpatienten -- Eine Querschnittsstudie unter deutschen Haus{\"a}rzten.},
      doi = {10.1055/a-1068-2348} }
  • [book] bibtex
    K. Hower, A. Poppe, V. Vennedey, H. A. Hillen, L. Kuntz, S. Stock, H. Pfaff, und L. Ansmann, Fragebogen zur Patientenorientierung in Versorgungsorganisationen in der Stadt Köln: Survey on Patient Orientation in Health and Social Care Organizations (SOPHIA): Kennzahlenhandbuch, , 2019.
    @book{Hower.2019d,
      author = {Hower, Kira and Poppe, Adriana and Vennedey, Vera and Hillen, Hendrik Ansgar and Kuntz, Ludwig and Stock, Stephanie and Pfaff, H. and Ansmann, Lena},
      year = {2019},
      title = {Fragebogen zur Patientenorientierung in Versorgungsorganisationen in der Stadt K{\"o}ln: Survey on Patient Orientation in Health and Social Care Organizations (SOPHIA): Kennzahlenhandbuch},
      institution = {{Institut f{\"u}r Medizinsoziologie, Universit{\"a}t zu K{\"o}ln} and {Institut f{\"u}r Gesundheits{\"o}konomie und Klinische Epidemiologie, Uniklinik K{\"o}ln} and {Department f{\"u}r Versorgungsforschung, Carl von Ossietzky Universit{\"a}t Oldenburg}} }
  • [article] bibtex
    M. Pladevall, A. Pottegård, T. Schink, J. Reutfors, R. Morros, B. Poblador-Plou, A. Timmer, J. Forns, M. Hellfritzsch, T. Reinders, D. Hägg, M. Giner-Soriano, A. Prados-Torres, M. Cainzos-Achirica, J. Hallas, L. Brandt, J. Cortés, J. Aguado, G. Perlemuter, B. Falissard, J. Castellsagué, E. Jacquot, N. Deltour, und S. Perez-Gutthann, "Risk of Acute Liver Injury in Agomelatine and Other Antidepressant Users in Four European Countries: A Cohort and Nested Case-Control Study Using Automated Health Data Sources" CNS Drugs, vol. (in press), 2019.
    @article{Pladevall.2019,
      author = {Pladevall, Manel and Potteg{\aa}rd, Anton and Schink, Tania and Reutfors, Johan and Morros, Rosa and Poblador-Plou, Beatriz and Timmer, Antje and Forns, Joan and Hellfritzsch, Maja and Reinders, Tammo and H{\"a}gg, David and Giner-Soriano, Maria and Prados-Torres, Alexandra and Cainzos-Achirica, Miguel and Hallas, Jesper and Brandt, Lena and Cort{\'e}s, Jordi and Aguado, Jaume and Perlemuter, Gabriel and Falissard, Bruno and Castellsagu{\'e},
      Jordi and Jacquot, Emmanuelle and Deltour, Nicolas and Perez-Gutthann, Susana},
      year = {2019},
      title = {Risk of Acute Liver Injury in Agomelatine and Other Antidepressant Users in Four European Countries: A Cohort and Nested Case-Control Study Using Automated Health Data Sources},
      volume = {(in press)},
      journal = {CNS Drugs} }
  • [article] bibtex
    M. Weßel, "Rez. Hentilä, Marjaliisa, Seppo Hentilä: 1918--Das deutsche Finnland. Die Rolle der Deutschen im finnischen Bürgerkrieg. Scoventa 2018, 430 S" Nordeuropaforum, pp. 21-23, 2019.
    @article{Weel.2019,
      author = {We{\ss}el, Merle},
      year = {2019},
      title = {Rez. Hentil{\"a},
      Marjaliisa, Seppo Hentil{\"a}: 1918--Das deutsche Finnland. Die Rolle der Deutschen im finnischen B{\"u}rgerkrieg. Scoventa 2018, 430 S},
      pages = {21--23},
      journal = {Nordeuropaforum} }
  • [book] bibtex
    K. Hower, V. Vennedey, H. A. Hillen, L. Kuntz, S. Stock, H. Pfaff, A. Poppe, und L. Ansmann, Merkmale und Determinanten einer patienten- und ressourcenorientierten Versorgung aus Sicht von Versorgungsorganisationen (OrgValue): Ergebnisse aus der Befragung von Entscheidungsträger*innen in Versorgungsorganisationen in der Stadt Köln, Köln: , 2019.
    @book{Hower.2019b,
      author = {Hower, Kira and Vennedey, Vera and Hillen, Hendrik Ansgar and Kuntz, Ludwig and Stock, Stephanie and Pfaff, H. and Poppe, Adriana and Ansmann, Lena},
      year = {2019},
      title = {Merkmale und Determinanten einer patienten- und ressourcenorientierten Versorgung aus Sicht von Versorgungsorganisationen (OrgValue): Ergebnisse aus der Befragung von Entscheidungstr{\"a}ger*innen in Versorgungsorganisationen in der Stadt K{\"o}ln},
      address = {K{\"o}ln},
      series = {Ver{\"o}ffentlichungsreihe des Instituts f{\"u}r Medizinsoziologie, Versorgungsforschung und Rehabilitationswissenschaft (IMVR) der Universit{\"a}t zu K{\"o}ln} }
  • [book] bibtex
    K. Hower, P. Saak, A. Schneider, O. Aydin, A. Poppe, H. Pfaff, und L. Ansmann, Evaluation des Fitkids-Programms zum gesunden Aufwachsen von Kindern suchterkrankter Eltern (EvaFit II): Ergebnisbericht, Köln: , 2019.
    @book{Hower.2019c,
      author = {Hower, Kira and Saak, Pamela and Schneider, Annika and Aydin, Osman and Poppe, Adriana and Pfaff, Holger and Ansmann, Lena},
      year = {2019},
      title = {Evaluation des Fitkids-Programms zum gesunden Aufwachsen von Kindern suchterkrankter Eltern (EvaFit II): Ergebnisbericht},
      address = {K{\"o}ln},
      institution = {{Institut f{\"u}r Medizinsoziologie, Versorgungsforschung und Rehabilitationswissenschaft (IMVR) der Universit{\"a}t zu K{\"o}ln}} }
  • [book] bibtex
    Jeszcze raz o staro\'sci z choroba / On Ageing and Illness, One More Time, Serkowska, H., Ganczar, M., Moczy'nska, J., und Tyniec, W. B., Eds., Krakau: Homini, 2019.
    @book{Serkowska.2019, year = {2019},
      title = {Jeszcze raz o staro{\'s}ci z choroba / On Ageing and Illness, One More Time},
      address = {Krakau},
      publisher = {Homini},
      editor = {Serkowska, Hanna and Ganczar, Maciej and Moczy{\'n}ska, Joanna and Tyniec, Wydawnictwo Benedyktyn{\'o}w} }
  • [article] bibtex
    J. I. Glitza, F. Müller-von-Aschwege, C. Feldmann, R. Wendl, J. D. Schmitto, N. Reiss, T. Schmidt, und A. Hein, "Analysis of LVAD Log Files Considering the Circadian Rhythm for Early Thrombosis Detection" The International Journal of Artificial Organs, 2019.
    @article{Glitza.2019,
      author = {Glitza, Jenny Inge and M{\"u}ller-von-Aschwege, Frerk and Feldmann, Christina and Wendl, Regina and Schmitto, Jan Dieter and Reiss, Nils and Schmidt, Thomas and Hein, Andreas},
      year = {2019},
      title = {Analysis of LVAD Log Files Considering the Circadian Rhythm for Early Thrombosis Detection},
      journal = {The International Journal of Artificial Organs},
      doi = {10.1177/0391398819860985},
      file = {Glitza et al. - 2019 - Analysis of LVAD Log Files Considering the Circadian Rhythm for Early Thrombosis Detection:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Glitza et al. - 2019 - Analysis of LVAD Log Files Considering the Circadian Rhythm for Early Thrombosis Detection.pdf:pdf} }
  • F. Kühne, A. L. Brütt, M. J. Otterbeck, und F. Weck, "Research priorities set by people with OCD and OCD researchers: Do the commonalities outweigh the differences?" Health Expect, 2019.
    @article{Kuhne.2019,
      author = {K{\"u}hne, F. and Br{\"u}tt, Anna Levke and Otterbeck, M. J. and Weck, F.},
      year = {2019},
      title = {Research priorities set by people with OCD and OCD researchers: Do the commonalities outweigh the differences?},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/31782245},
      journal = {Health Expect},
      doi = {10.1111/hex.13005} }
  • [article] bibtex
    F. Otto-Sobotka, N. Salvati, M. G. Ranalli, und T. Kneib, "Adaptive Semiparametric M-Quantile Regression" Econometrics and Statistics, vol. 11, pp. 116-129, 2019.
    @article{OttoSobotka.2019,
      author = {Otto-Sobotka, F. and Salvati, N. and Ranalli, M. G. and Kneib, T.},
      year = {2019},
      title = {Adaptive Semiparametric M-Quantile Regression},
      pages = {116--129},
      volume = {11},
      journal = {Econometrics and Statistics} }
  • Handbuch Innovationsforschung, Living reference work ed., Blättel-Mink, B., Schulz-Schaeffer, I., und Windeler, A., Eds., , 2019.
    @book{BlattelMink.2019, year = {2019},
      title = {Handbuch Innovationsforschung},
      url = {https://doi.org/10.1007/978-3-658-17671-6},
      edition = {Living reference work},
      isbn = {978-3-658-17671-6},
      editor = {Bl{\"a}ttel-Mink, Birgit and Schulz-Schaeffer, Ingo and Windeler, Arnold} }
  • [incollection] bibtex
    K. Hower, T. Pförtner, H. Pfaff, M. Wensing, und L. Ansmann, "Innovationen im Gesundheitswesen" in Handbuch Innovationsforschung, Blättel-Mink, B., Schulz-Schaeffer, I., und Windeler, A., Eds., , 2019.
    @incollection{Hower.2019e,
      author = {Hower, Kira and Pf{\"o}rtner, Timo-Kolja and Pfaff, Holger and Wensing, Michel and Ansmann, Lena},
      title = {Innovationen im Gesundheitswesen},
      isbn = {978-3-658-17671-6},
      editor = {Bl{\"a}ttel-Mink, Birgit and Schulz-Schaeffer, Ingo and Windeler, Arnold},
      booktitle = {Handbuch Innovationsforschung},
      year = {2019} }
  • [article] bibtex
    S. Kappen, V. Jürgens, M. H. Freitag, und A. Winter, "Early detection of prostate cancer using prostate-specific antigen testing: an empirical evaluation among general practitioners and urologists" Cancer Management Research, vol. 11, pp. 3079-3097, 2019.
    @article{Kappen.2019,
      author = {Kappen, S. and J{\"u}rgens, Verena and Freitag, Michael H. and Winter, A.},
      year = {2019},
      title = {Early detection of prostate cancer using prostate-specific antigen testing: an empirical evaluation among general practitioners and urologists},
      pages = {3079--3097},
      volume = {11},
      journal = {Cancer Management Research},
      doi = {10.2147/CMAR.S193325} }
  • [article] bibtex
    A. Münzberg, J. Sauer, S. Lämmel, T. Susanne, A. Arens-Volland, M. Eichelberg, und A. Hein, "Digital Supported Diagnostics In Food Allergy By Analyzing App-Based Diaries" Allergy, Meeting Abstract, Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), vol. 74, p. 153, 2019.
    @article{Munzberg.2019,
      author = {M{\"u}nzberg, Alexander and Sauer, Janina and L{\"a}mmel, Sonja and Susanne, Teichmann and Arens-Volland, Andreas and Eichelberg, Marco and Hein, Andreas},
      year = {2019},
      title = {Digital Supported Diagnostics In Food Allergy By Analyzing App-Based Diaries},
      pages = {153},
      volume = {74},
      journal = {Allergy, Meeting Abstract, Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI)},
      file = {Rösch et al. - 2019 - Digital supported diagnostics in food allergy by analyzing app-based diaries:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Rösch et al. - 2019 - Digital supported diagnostics in food allergy by analyzing app-based diaries.pdf:pdf} }
  • [article] bibtex
    M. Nowak, M. Swora, U. Karbach, H. Pfaff, und L. Ansmann, "Associations between hospital structures, processes and patient experiences of preparation for discharge in breast cancer centers: A multilevel analysis" Health care management review, 2019.
    @article{Nowak.2019, abstract = {BACKGROUND Discharge management is a central task in hospital management. Mitchell's quality health outcomes model offers a contextual framework to derive expectations about the relationship between indicators of hospital structures and processes with patient experiences of preparation for discharge. PURPOSE The aim is to analyze the association between hospital structures and processes with patient experiences of preparation for discharge in breast cancer centers. METHODOLOGY The data were collected between February 1 and July 31, 2014-2016, with annual cross-sectional postal surveys on patient experiences of preparation for discharge in breast cancer center hospitals in Germany. These data were combined with secondary data on hospital structures, obtained from structured quality reports 2014 and the accreditation institution certifying breast cancer centers, constituting a hierarchical data structure. A total of 10,750 newly diagnosed breast cancer patients from 67 hospitals were analyzed. Following listwise deletion, 9,762 patients could be included in linear hierarchical regression analyses. RESULTS Patients felt better prepared for discharge in hospitals that communicate the discharge date timely to patients, with good coordinative processes, and which cooperate with two other breast cancer center hospitals. Hospital structures, size, teaching status, and ownership were not associated with the patient experiences of preparation for discharge. CONCLUSION The results suggest that timely and informative communication, well-organized care processes, and the network structure of centers allow for an improvement of preparation for discharge. Current and future approaches for the improvement of hospital discharge should consider the identified hospital resources. PRACTICE IMPLICATIONS Hospital management should increase the focus on structured communication and coordination processes to improve the discharge process. Cooperating networks should be expanded to increase expertise and resources. Results can be generalized to other care domains with caution. Patients' characteristics should further be assessed in order to use resources efficiently.},
      author = {Nowak, Marina and Swora, Michael and Karbach, Ute and Pfaff, Holger and Ansmann, Lena},
      year = {2019},
      title = {Associations between hospital structures, processes and patient experiences of preparation for discharge in breast cancer centers: A multilevel analysis},
      journal = {Health care management review},
      doi = {10.1097/HMR.0000000000000237},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30807374} }
  • [article] bibtex
    A. Timmer, J. Peplies, und S. Koletzko, "Erwachsenwerden mit CED: Ergebnisse der DCCV geförderten \glqqTransitionsstudie\grqq" Bauchredner, vol. 2019, iss. 1, pp. 86-92, 2019.
    @article{Timmer.2019b,
      author = {Timmer, Antje and Peplies, Jenny and Koletzko, Sibylle},
      year = {2019},
      title = {Erwachsenwerden mit CED: Ergebnisse der DCCV gef{\"o}rderten {\glqq}Transitionsstudie{\grqq}},
      pages = {86--92},
      volume = {2019},
      number = {1},
      journal = {Bauchredner} }
  • [inproceedings] bibtex
    P. Gliesche, M. Pfingsthorn, C. Kowalski, S. Drolshagen, T. Krahn, und A. Hein, "Erster Vergleich von Eingabegeräten für die Telemanipulation im Pflegekontext" in Proc. Zukunft der Pflege Tagungsband der 2. Clusterkonferenz, 2019, pp. 35-36.
    @inproceedings{Gliesche.2019, abstract = {Hintergrund / Fragestellung: Der Pflegenotstand erfordern innovative technologische L{\"o}sungen, wie z.B. Roboteranwendungen. V{\"o}llig autonom agierende Roboter im Bereich der Pflege sind in naher Zukunft nicht realistisch. Daher m{\"u}ssen semiautonome Systeme betrachtet werden, die von Pflegekr{\"a}ften gesteuert werden k{\"o}nnen. Es gibt noch keine Erfahrungen mit welchem Eingabeger{\"a}t Pflegekr{\"a}fte am besten einen Manipulator steuern und damit bei Aufgaben unterst{\"u}tzen k{\"o}nnen. Hier werden in einer ersten Studie verschiedene im Handel erh{\"a}ltliche Eingabeger{\"a}te verglichen. Methodik: Der Manipulator und dessen Bediener befinden sich in zwei unterschiedlichen R{\"a}umen. Der Bediener steuert aus der Perspektive des von der Spitze des Manipulators {\"u}bertragenen Kamerabildes. Nach einer Anlernphase bearbeiten die Nutzer zwei Aufgaben zweimal (Anreichen einer Fernbedienung, Einstellen eines bestimmten Bildes) mit jeweils allen vier Eingabeger{\"a}ten (Tastatur {\&} Maus, XBOX Controller, Novint Falcon 3D Haptic Controller und 3DConnexion SpaceMouse) in zuf{\"a}lliger Reihenfolge. Dabei werden jeweils die Ausf{\"u}hrungszeiten bestimmt. Gebrauchstauglichkeit und Belastungen werden {\"u}ber Frageb{\"o}gen abgefragt. Ergebnisse: Die Ergebnisse der Vorstudie zeigen, dass mit dem Novint Falcon 3D Haptic Controller die besten Ausf{\"u}hrungszeiten erreicht und die Tastatur {\&} Maus am bedienbarsten und am wenigsten belastend empfunden werden. Nicht alle Probanden konnten mit jedem Ger{\"a}t jede Aufgabe erfolgreich bearbeiten. Schlussfolgerungen: Die Nutzer k{\"o}nnen nach einer kurzen Anlernphase einen Manipulator sicher steuern. Aufgrund der Ergebnisse der Vorstudie, wird f{\"u}r die Studie geschlussfolgert, dass die Untersuchung auf die zwei Ger{\"a}te reduziert wird, die die besten Ausf{\"u}hrungszeiten (Novint Falcon 3D Haptic Controller) und die beste Gebrauchstauglichkeit (Tastatur {\&} Maus) hatten. Diese werden in der folgenden Studie n{\"a}her untersucht.},
      author = {Gliesche, Pascal and Pfingsthorn, Max and Kowalski, Christian and Drolshagen, Sandra and Krahn, Tobias and Hein, Andreas},
      title = {Erster Vergleich von Eingabeger{\"a}ten f{\"u}r die Telemanipulation im Pflegekontext},
      pages = {35--36},
      booktitle = {Zukunft der Pflege Tagungsband der 2. Clusterkonferenz},
      year = {2019},
      file = {Gliesche et al. - 2019 - Erster Vergleich von Eingabegeräten für die Telemanipulation im Pflegekontext:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gliesche et al. - 2019 - Erster Vergleich von Eingabegeräten für die Telemanipulation im Pflegekontext.pdf:pdf} }
  • [inproceedings] bibtex
    N. Rösch, A. Münzberg, J. Sauer, S. Lämmel, S. Teichmann, A. Arens-Volland, M. Eichelberg, und A. Hein, "Digital supported diagnostics in food allergy by analyzing app-based diaries" in Proc. Proceedings 2019 Congress of the European Academy of Allergy and Clinical Immunology (EAACI), Lisbon, 2019, p. 153.
    @inproceedings{Rosch.2019,
      author = {R{\"o}sch, Norbert and M{\"u}nzberg, Alexander and Sauer, Janina and L{\"a}mmel, Sonja and Teichmann, Susanne and Arens-Volland, Andreas and Eichelberg, Marco and Hein, Andreas},
      title = {Digital supported diagnostics in food allergy by analyzing app-based diaries},
      pages = {153},
      booktitle = {Proceedings 2019 Congress of the European Academy of Allergy and Clinical Immunology (EAACI)},
      year = {2019},
      address = {Lisbon},
      file = {Rösch et al. - 2019 - Digital supported diagnostics in food allergy by analyzing app-based diaries:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Rösch et al. - 2019 - Digital supported diagnostics in food allergy by analyzing app-based diaries.pdf:pdf} }
  • L. Ansmann und S. Nöst, "Gute Versorgung - eine Frage der Organisation? Grundlagen der organisationsbezogenen Versorgungsforschung" Monitor Versorgungsforschung, vol. 12, iss. 3, pp. 49-50, 2019.
    @article{Ansmann.2019b,
      author = {Ansmann, Lena and N{\"o}st, Stefan},
      year = {2019},
      title = {Gute Versorgung - eine Frage der Organisation? Grundlagen der organisationsbezogenen Versorgungsforschung},
      url = {https://www.monitor-versorgungsforschung.de/ausgaben/aktuelle-ausgabe/view},
      pages = {49--50},
      volume = {12},
      number = {3},
      journal = {Monitor Versorgungsforschung} }
  • [article] bibtex
    F. Otto-Sobotka, J. Peplies, und A. Timmer, "Modeling determinants of satisfaction with health care in youth with inflammatory bowel disease part 2: semiparametric distributional regression" Clinical Epidemiology, vol. 11, pp. 403-417, 2019.
    @article{OttoSobotka.2019b,
      author = {Otto-Sobotka, F. and Peplies, Jenny and Timmer, Antje},
      year = {2019},
      title = {Modeling determinants of satisfaction with health care in youth with inflammatory bowel disease part 2: semiparametric distributional regression},
      pages = {403--417},
      volume = {11},
      issn = {1179-1349 (Print) 1179-1349},
      journal = {Clinical Epidemiology},
      doi = {10.2147/CLEP.S191458} }
  • [article] bibtex
    C. Pinkert, K. Köhler, M. von Kutzleben, I. Hochgräber, C. Cavazzini, S. Völz, R. Palm, und B. Holle, "Social inclusion of people with dementia -- an integrative review of theoretical frameworks, methods and findings in empirical studies" Ageing and Society, vol. 2, pp. 1-21, 2019.
    @article{Pinkert.2019,
      author = {Pinkert, Christiane and K{\"o}hler, Kerstin and {von Kutzleben},
      Milena and Hochgr{\"a}ber, Iris and Cavazzini, Christoph and V{\"o}lz, Silke and Palm, Rebecca and Holle, Bernhard},
      year = {2019},
      title = {Social inclusion of people with dementia -- an integrative review of theoretical frameworks, methods and findings in empirical studies},
      pages = {1--21},
      volume = {2},
      issn = {0144-686X},
      journal = {Ageing and Society},
      doi = {10.1017/S0144686X19001338} }
  • [article] bibtex
    D. Scholze, L. Stange, D. Palm, und F. Koppelin, "Heterogenen Lernendengruppen in der wissenschaftlichen Weiterbildung im Bereich Public Health begegnen" Zeitschrift fÃ\textonequarterr Hochschulentwicklung, vol. 14, iss. 4, pp. 91-107, 2019.
    @article{Scholze.2019,
      author = {Scholze, Dafna and Stange, Lena and Palm, Doris and Koppelin, Frauke},
      year = {2019},
      title = {Heterogenen Lernendengruppen in der wissenschaftlichen Weiterbildung im Bereich Public Health begegnen},
      pages = {91--107},
      volume = {14},
      number = {4},
      issn = {2219-6994},
      journal = {Zeitschrift f{\~A}{\textonequarter}r Hochschulentwicklung} }
  • M. Schweda, "Ethik des Alterns zwischen Autonomie und Fürsorge" Praxis PalliativeCare, vol. 43, pp. 26-28, 2019.
    @article{Schweda.2019c,
      author = {Schweda, Mark},
      year = {2019},
      title = {Ethik des Alterns zwischen Autonomie und F{\"u}rsorge},
      url = {http://kxp.k10plus.de/DB=2.1/PPNSET?PPN=1693713233},
      pages = {26--28},
      volume = {43},
      issn = {1867-7126},
      journal = {Praxis PalliativeCare} }
  • [article] bibtex
    E. Spiegel, T. Kneib, und F. Otto-Sobotka, "Spatio-temporal expectile regression models" Statistical Modeling, vol. 20, iss. 4, pp. 386-409, 2019.
    @article{Spiegel.2019,
      author = {Spiegel, Elmar and Kneib, T. and Otto-Sobotka, F.},
      year = {2019},
      title = {Spatio-temporal expectile regression models},
      pages = {386--409},
      volume = {20},
      number = {4},
      journal = {Statistical Modeling},
      doi = {10.1177/1471082X19829945} }
  • [article] bibtex
    A. Timmer, D. de Sordi, S. Kappen, K. P. Kohse, T. Schink, S. Perez-Gutthann, E. Jacquot, N. Deltour, und M. Pladevall, "Validity of hospital ICD-10-GM codes to identify acute liver injury in Germany" Pharmacoepidemiol Drug Saf, vol. 28, iss. 10, pp. 1344-1352, 2019.
    @article{Timmer.2019,
      author = {Timmer, Antje and {de Sordi},
      D. and Kappen, S. and Kohse, K. P. and Schink, Tania and Perez-Gutthann, Susana and Jacquot, Emmanuelle and Deltour, Nicolas and Pladevall, Manel},
      year = {2019},
      title = {Validity of hospital ICD-10-GM codes to identify acute liver injury in Germany},
      pages = {1344--1352},
      volume = {28},
      number = {10},
      issn = {1053-8569},
      journal = {Pharmacoepidemiol Drug Saf} }
  • [article] bibtex
    N. Wirsik, F. Otto-Sobotka, und I. Pigeot, "Modeling physical Activity using L0-penalised expectile regression" Biometrical Journal, vol. 61, iss. 6, pp. 1371-1384, 2019.
    @article{Wirsik.2019,
      author = {Wirsik, Norman and Otto-Sobotka, F. and Pigeot, Iris},
      year = {2019},
      title = {Modeling physical Activity using L0-penalised expectile regression},
      pages = {1371--1384},
      volume = {61},
      number = {6},
      journal = {Biometrical Journal},
      doi = {10.1002/bimj.201800007} }
  • [article] bibtex
    A. Zeleke, A. G. Worku, A. Demissie, F. Otto-Sobotka, M. Wilken, M. Lipprandt, B. Tilahun, und R. Röhrig, "Evaluation of Electronic and Paper Pen Data Capturing Tools for Data Quality in a Public Health Survey in a Health and Demographic Surveillance Site, Ethiopia: A randomized controlled crossover Healthcare IT-Evaluation" JMIR MHealth and Uhealth, vol. 7, iss. 2, p. 10995, 2019.
    @article{Zeleke.2019,
      author = {Zeleke, Atinkut and Worku, A. G. and Demissie, A. and Otto-Sobotka, F. and Wilken, Marc and Lipprandt, Myriam and Tilahun, B. and R{\"o}hrig, Rainer},
      year = {2019},
      title = {Evaluation of Electronic and Paper Pen Data Capturing Tools for Data Quality in a Public Health Survey in a Health and Demographic Surveillance Site, Ethiopia: A randomized controlled crossover Healthcare IT-Evaluation},
      pages = {e10995},
      volume = {7},
      number = {2},
      journal = {JMIR MHealth and Uhealth},
      doi = {10.2196/10995} }
  • [incollection] bibtex
    M. Schweda, "Konzeptionen der Demenz im Wandel und ihre ethischen Implikationen [auf Polnisch]" in Jeszcze raz o staro\'sci z choroba / On Ageing and Illness, One More Time, Serkowska, H., Ganczar, M., Moczy'nska, J., und Tyniec, W. B., Eds., Krakau: Homini, 2019, pp. 17-32.
    @incollection{Schweda.2019b,
      author = {Schweda, Mark},
      title = {Konzeptionen der Demenz im Wandel und ihre ethischen Implikationen [auf Polnisch]},
      pages = {17--32},
      publisher = {Homini},
      editor = {Serkowska, Hanna and Ganczar, Maciej and Moczy{\'n}ska, Joanna and Tyniec, Wydawnictwo Benedyktyn{\'o}w},
      booktitle = {Jeszcze raz o staro{\'s}ci z choroba / On Ageing and Illness, One More Time},
      year = {2019},
      address = {Krakau} }
  • [inproceedings] bibtex
    C. Fifelski, M. Peters, S. Daxberger, L. Wirth, C. Kowalski, A. Hein, und M. Hülsken-Giesler, "Multifunktionale, technikgestützte Mobilisierung in der Pflege" in Proc. Zukunft der Pflege Tagungsband der 2. Clusterkonferenz, 2019, pp. 97-98.
    @inproceedings{Fifelski.2019, abstract = {Die Mobilisierung Pflegebed{\"u}rftiger bringt Belastungen mit sich, die k{\"o}rperliche Sch{\"a}digungen bei den Pflegenden verursachen k{\"o}nnen (J{\"a}ger et al., 2014). Pflegehilfsmittel, wie Lifterund Pflegebetten, zielen darauf ab, k{\"o}rperliche Belastungen zu minimieren. Hilfsmittel dieser Art sind im Normalfall f{\"u}r ausgew{\"a}hlte Anwendungszwecke vorgesehen. F{\"u}r komplexe Pflegesituationen sind oft mehrere unterschiedliche Hilfsmittel zu kombinieren, was wirtschaftlich fraglich ist, den Pflegekr{\"a}ften ein sicheres Handling mit unterschiedlich funktionierenden Ger{\"a}ten abverlangt und letztlich dazu f{\"u}hren kann, dass die zur Verf{\"u}gung stehende technische Infrastruktur nicht genutzt wird. Im Pflegelabor der Universit{\"a}t Oldenburg wird auf Grundlage des BMBF gef{\"o}rderten Projektes ITAGAP ein alternativer Ansatz gew{\"a}hlt: ein multifunktionaler Roboterarm, der an einem Pflegebett befestigt wird, leistet Unterst{\"u}tzung in verschiedenen Pflegesituationen. Er unterst{\"u}tzt die von einer Pflegeperson koordinierte Lagerung von Klient(inn)en im Bett, die Mobilisation und den Transfer vom Bett in den Stuhl und ist in der Lage, Gegenst{\"a}nde f{\"u}r die Klient(inn)en oder die Pflegepersonen anzureichen oder zu halten. Mit diesem Ansatz soll eine k{\"o}rperliche Entlastung von Pflegenden erreicht und die Unabh{\"a}ngigkeit von bettl{\"a}gerigen Klient(inn)en unterst{\"u}tzt werden. Die Technologieentwicklung erfolgt mit pflegewissenschaftlicher Begleitung und in Zusammenarbeit mit der Pflegepraxis. Erste Testl{\"a}ufe mit Auszubilden den in der Pflege demonstrieren die Multi-funktionalit{\"a}t des Systems, belegen die Machbarkeit und geben Anlass, diesen innovativen Ansatz weiter zu verfolgen.},
      author = {Fifelski, Conrad and Peters, Miriam and Daxberger, Sabine and Wirth, Lena-Marie and Kowalski, Christian and Hein, Andreas and H{\"u}lsken-Giesler, Manfred},
      title = {Multifunktionale, technikgest{\"u}tzte Mobilisierung in der Pflege},
      keywords = {Kin{\"a}sthetics;Nursing;Robotics},
      pages = {97--98},
      booktitle = {Zukunft der Pflege Tagungsband der 2. Clusterkonferenz},
      year = {2019},
      file = {Fifelski et al. - 2019 - Multifunktionale, technikgestützte Mobilisierung in der Pflege:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Fifelski et al. - 2019 - Multifunktionale, technikgestützte Mobilisierung in der Pflege.pdf:pdf} }
  • [inproceedings] bibtex
    A. Gerka, B. Cauchi, und A. Hein, "Multivariate Event Detection for Non-Intrusive Load Monitoring" in Proc. AMBIENT 2019 : The Ninth International Conference on Ambient Computing, Applications, Services and Technologies Multivariate, 2019, pp. 25-30.
    @inproceedings{Gerka.2019c,
      author = {Gerka, Alexander and Cauchi, Benjamin and Hein, Andreas},
      title = {Multivariate Event Detection for Non-Intrusive Load Monitoring},
      keywords = {event detection;hotelling-t 2 statistic;nilm},
      pages = {25--30},
      isbn = {978-1-61208-739-9},
      booktitle = {AMBIENT 2019 : The Ninth International Conference on Ambient Computing, Applications, Services and Technologies Multivariate},
      year = {2019},
      file = {Gerka, Cauchi, Hein - 2019 - Multivariate Event Detection for Non-Intrusive Load Monitoring:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka, Cauchi, Hein - 2019 - Multivariate Event Detection for Non-Intrusive Load Monitoring.pdf:pdf} }
  • [inproceedings] bibtex
    R. Kappes, S. Fudickar, J. Deiters, A. Matviienko, J. Heinovski, M. Franke, F. Klingler, C. Sommer, F. Dressler, A. Johnson, W. Funk, C. Kraetsch, L. Brink-Abeler, M. Isken, S. Boll, W. Heuten, und A. Hein, "Safety4Bikes : Assistance Systems for Cycling Children to Increase Safety" in Proc. International Cycling Safety Conference - Abstract Book, 2019, p. 71.
    @inproceedings{Kappes.2019, abstract = {Cycling is a popular urban mobility solution. However, cyclists are more vulnerable and relatively unprotected compared to other road users. In Germany, the number of accidents with cycling children increases dramatically between the ages of 8 and 14 years, which is caused by their not fully developed cycling skills and understanding of traffic. The project Safety4Bikes aims at mitigating the risk of young cyclists by developing appropriate modular assistance systems that detect situational hazards and promote safe behaviour. Within the project, we are developing novel visual, tactile and acoustic signals integrated in bicycles and helmets to convey information for children in an understandable and non-distracting way. Embedding the cyclist into the surrounding context, we develop and investigate sensor technologies, algorithms and routing strategies needed for identification of the behaviour of cyclists on the road, traffic signs, safest routes and trajectory corrections. Additionally, we focus on the enhancements of Car2X communication to enable the exchange of information with other vehicles. The project follows a user centric approach in which the developed system components are continuously tested and adapted to the needs and characteristics of the target group. Answering the question of how the components will have to interact with the user is an important part of the research. Therefore, we evaluate the efficacy of the designed interaction and recognition methods as well as sensors, algorithms and routing strategies through laboratory experiments and bicycle simulators. With controlled test-track experiments on a test route, the components are further evaluated and optimised.},
      author = {Kappes, Raphael and Fudickar, Sebastian and Deiters, Jule and Matviienko, Andrii and Heinovski, Julian and Franke, M. and Klingler, F. and Sommer, C. and Dressler, Falko and Johnson, A. and Funk, Walter and Kraetsch, C. and Brink-Abeler, Lennart and Isken, Melvin and Boll, Susanne and Heuten, Wilko and Hein, Andreas},
      title = {Safety4Bikes : Assistance Systems for Cycling Children to Increase Safety},
      keywords = {Cycling;S4B;Safety;Safety4Bikes},
      pages = {71},
      booktitle = {International Cycling Safety Conference - Abstract Book},
      year = {2019},
      file = {Kappes et al. - 2019 - Safety4Bikes Assistance Systems for Cycling Children to Increase Safety:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Kappes et al. - 2019 - Safety4Bikes Assistance Systems for Cycling Children to Increase Safety.pdf:pdf} }
  • [inproceedings] bibtex
    C. Kowalski, P. Arizpe-Gomez, S. Weiß, P. Gliesche, und A. Hein, "Intuitive human-robot interaction for physical support during nursing activities using myoelectric signals" in Proc. Zukunft der Pflege Tagungsband der 2. Clusterkonferenz, 2019, p. 92.
    @inproceedings{Kowalski.2019b, abstract = {Nurses are exposed to immense physical strain, which often leads to early retirement from work. Due to the prevailing care crisis, it is therefore important to provide support in this domain to counteract the loss of nursing staff. A large potential resides in the use of robotics for physical relief by supporting during patient positioning activities. In any form of human-robot interaction with assistance systems, the difficulty lies in the ideal selection of concepts for initiating actions on the part of the robot -- especially in safety critical environments. For this reason, the present scientific work deals with the implementation of an intuitive interaction concept for non-contact communication with a robotic manipulator attached to the patient bed, which can support both patient and nurse. For such an interaction concept, the robot needs to gather information about when and where to move to in order to support properly. In our case, the communication of when to move is done by recognizing a specific gesture based on myoelectric signals of the nurse's lower arm using a Myo wristband. Moreover, the target location is the nurse's current hand position calculated in three-dimensional space by using image data from external cameras. During nursing activities, the nurse initiates the movement of the robot arm by using a gesture like fin-ger spreading. The results show that this kind of interaction is feasible for positioning movements which require little to moderate force -- high-force movements are less likely to be detected reliably with the Myo wristband.},
      author = {Kowalski, Christian and Arizpe-Gomez, Pedro and Wei{\ss},
      Sebastian and Gliesche, Pascal and Hein, Andreas},
      title = {Intuitive human-robot interaction for physical support during nursing activities using myoelectric signals},
      keywords = {Human-Robot Interaction;Nursing Care In-novation Center (PIZ);Physical Robot Support;Pose Detection},
      pages = {92},
      booktitle = {Zukunft der Pflege Tagungsband der 2. Clusterkonferenz},
      year = {2019},
      file = {Kowalski et al. - 2019 - Intuitive human-robot interaction for physical support during nursing activities using myoelectric signals:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Kowalski et al. - 2019 - Intuitive human-robot interaction for physical support during nursing activities using myoelectric signals.pdf:pdf} }
  • [article] bibtex
    C. Bachmann, J. Höfer, I. Kamp-Becker, L. Poustka, V. Roessner, S. Stroth, N. Wolff, und F. Hoffmann, "Affiliate stigma in caregivers of children and adolescents with autism spectrum disorder in Germany" Psychiatry Res, vol. 284, p. 112483, 2019.
    @article{Bachmann.2019,
      author = {Bachmann, C. and H{\"o}fer, J. and Kamp-Becker, I. and Poustka, L. and Roessner, V. and Stroth, S. and Wolff, N. and Hoffmann, Falk},
      year = {2019},
      title = {Affiliate stigma in caregivers of children and adolescents with autism spectrum disorder in Germany},
      pages = {112483},
      volume = {284},
      issn = {1872-7123 (Electronic) 0165-1781 (Linking)},
      journal = {Psychiatry Res},
      doi = {10.1016/j.psychres.2019.112483},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31377007} }
  • [article] bibtex
    K. Beier, M. Schweda, und S. Schicktanz, "Taking patient involvement seriously: a critical ethical analysis of participatory approaches in data-intensive medical research" BMC Medical Informatics and Decision Making, vol. 19, iss. 1, p. 90, 2019.
    @article{Beier.2019,
      author = {Beier, Katharina and Schweda, Mark and Schicktanz, Silke},
      year = {2019},
      title = {Taking patient involvement seriously: a critical ethical analysis of participatory approaches in data-intensive medical research},
      pages = {90},
      volume = {19},
      number = {1},
      issn = {1472-6947},
      journal = {BMC Medical Informatics and Decision Making},
      doi = {10.1186/s12911-019-0799-7} }
  • [article] bibtex
    K. Beier, C. Schickhardt, H. Langhof, T. Schumacher, E. C. Winkler, und M. Schweda, "Effiziente medizinische Forschung oder gläserner Patient? Szenarien der Big Data Medizin -- Ethische und soziale Aspekte der Datenintegration im Gesundheitswesen" Ethik in der Medizin, vol. 31, iss. 3, pp. 261-266, 2019.
    @article{Beier.2019b,
      author = {Beier, Katharina and Schickhardt, Christoph and Langhof, Holger and Schumacher, Tobin and Winkler, Eva C. and Schweda, Mark},
      year = {2019},
      title = {Effiziente medizinische Forschung oder gl{\"a}serner Patient? Szenarien der Big Data Medizin -- Ethische und soziale Aspekte der Datenintegration im Gesundheitswesen},
      pages = {261--266},
      volume = {31},
      number = {3},
      issn = {0935-7335},
      journal = {Ethik in der Medizin},
      doi = {10.1007/s00481-019-00541-6} }
  • [article] bibtex
    A. Diekmann, C. Heuser, N. Ernstmann, F. Geiser, S. E. Groß, E. Midding, H. Pfaff, und L. Ansmann, "How do breast cancer patients experience multidisciplinary tumor conferences? - A description from the patient perspective" Breast (Edinburgh, Scotland), vol. 44, pp. 66-72, 2019.
    @article{Diekmann.2019, abstract = {OBJECTIVES Aim of this study was to investigate the experiences of breast cancer patients who participated in multidisciplinary tumor conferences (MTCs). STUDY DESIGN Data from two consecutive years of an annual postal survey of patients with primary breast cancer were combined. Data was collected between February and July 2015 (response rate 72{\%}) and 2016 (response rate 73{\%}) from N = 8893 patients (ICD-10 C50) after hospital discharge from 86 breast cancer center hospitals in North Rhine-Westphalia, Germany. The study used a mixed-methods design. Standardized quantitative survey questions were analyzed descriptively and an open-ended question was analyzed using qualitative content analysis. RESULTS Around 9{\%} of the patients were invited to participate in a multidisciplinary tumor conference (MTC) and 49{\%} of the invited patients reported actual participation in a MTC. Approximately 87{\%} of those patients did not regret their participation in the MTC. The qualitative analysis from the open-ended question indicated that MTC participation was perceived by patients as being both supportive and informative (n = 109 expressions). However, some patients reported difficult experiences and emotional reactions during and after participation (n = 37 expressions). Altogether, the patients' perception was divided into positive and negative, cognitive and emotional experiences following participation in a MTC. CONCLUSION The perception of the MTCs varies between the participating patients. Further research on advantages and disadvantages for patients and particularly on the feasibility from the provider's perspective is necessary.},
      author = {Diekmann, Annika and Heuser, Christian and Ernstmann, Nicole and Geiser, Franziska and Gro{\ss},
      Sophie Elisabeth and Midding, Evamarie and Pfaff, Holger and Ansmann, Lena},
      year = {2019},
      title = {How do breast cancer patients experience multidisciplinary tumor conferences? - A description from the patient perspective},
      pages = {66--72},
      volume = {44},
      journal = {Breast (Edinburgh, Scotland)},
      doi = {10.1016/j.breast.2018.12.012},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30669033} }
  • [article] bibtex
    B. Friedrich, B. Cauchi, A. Hein, und S. Fudickar, "Transportation mode classification from smartphone sensors via a long-short-term-memory network" UbiComp/ISWC 2019- - Adjunct Proceedings of the 2019 ACM International Joint Conference on Pervasive and Ubiquitous Computing and Proceedings of the 2019 ACM International Symposium on Wearable Computers, pp. 709-713, 2019.
    @article{Friedrich.2019, abstract = {This article introduce the architecture of a Long-Short-Term-Memory network for classifying transportation-modes via smartphone data and evaluates its accuracy. By using a Long-Short-Term-Memory with common preprocessing steps such as normalisation for classification tasks an F1-Score accuracy of 63.68 {\%} was achieved with an internal test dataset. We participated as team {\textquotedbl}GanbareAMT{\textquotedbl} in the {\grqq}SHL recognition challenge{\textquotedbl}.},
      author = {Friedrich, Bj{\"o}rn and Cauchi, Benjamin and Hein, Andreas and Fudickar, Sebastian},
      year = {2019},
      title = {Transportation mode classification from smartphone sensors via a long-short-term-memory network},
      keywords = {Classification;IMU;Inertial;LSTM;Mode of Transportation;Phones;Supervised Machine Learning},
      pages = {709--713},
      journal = {UbiComp/ISWC 2019- - Adjunct Proceedings of the 2019 ACM International Joint Conference on Pervasive and Ubiquitous Computing and Proceedings of the 2019 ACM International Symposium on Wearable Computers},
      doi = {10.1145/3341162.3344855},
      file = {Friedrich et al. - 2019 - Transportation mode classification from smartphone sensors via a long-short-term-memory network:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Friedrich et al. - 2019 - Transportation mode classification from smartphone sensors via a long-short-term-memory network.pdf:pdf} }
  • [article] bibtex
    U. Hoffmann, U. Drescher, L. Thieschäfer, und J. Koschate, "Living In Confinement Conditions: Physical Training Can Improve Muscular Oxygen Uptake and Heart Rate Kinetics" Medicine & Science in Sports & Exercise, vol. 51, iss. 6S, p. 465, 2019.
    @article{Hoffmann.2019b,
      author = {Hoffmann, Uwe and Drescher, Uwe and Thiesch{\"a}fer, Lutz and Koschate, Jessica},
      year = {2019},
      title = {Living In Confinement Conditions: Physical Training Can Improve Muscular Oxygen Uptake and Heart Rate Kinetics},
      pages = {465},
      volume = {51},
      number = {6S},
      issn = {0195-9131},
      journal = {Medicine {\&} Science in Sports {\&} Exercise},
      doi = {10.1249/01.mss.0000561897.76023.dc} }
  • [article] bibtex
    K. Hower, T. Pförtner, H. Pfaff, S. D. Lee, und L. Ansmann, "Child-oriented Drug Counseling in Germany: Evaluating the Implementation of the Program ``Fitkids'' and Its Association with Readiness for Change" Human Service Organizations: Management, Leadership & Governance, vol. 43, iss. 5, pp. 421-442, 2019.
    @article{Hower.2019f,
      author = {Hower, Kira and Pf{\"o}rtner, Timo-Kolja and Pfaff, Holger and Lee, Shoou-Yih Daniel and Ansmann, Lena},
      year = {2019},
      title = {Child-oriented Drug Counseling in Germany: Evaluating the Implementation of the Program ``Fitkids'' and Its Association with Readiness for Change},
      pages = {421--442},
      volume = {43},
      number = {5},
      issn = {2330-3131},
      journal = {Human Service Organizations: Management, Leadership {\&} Governance},
      doi = {10.1080/23303131.2019.1661929} }
  • [article] bibtex
    J. Koschate, S. Lau, T. Zieschang, und U. Hoffmann, "28 Cardiorespiratory Regulation and Aerobic Fitness in Older People -- A New Approach for Falls Interventions?" Age and Ageing, vol. 48, iss. Supplement_4, p. iv6-iv8, 2019.
    @article{Koschate.2019,
      author = {Koschate, Jessica and Lau, Sandra and Zieschang, Tania and Hoffmann, Uwe},
      year = {2019},
      title = {28 Cardiorespiratory Regulation and Aerobic Fitness in Older People -- A New Approach for Falls Interventions?},
      pages = {iv6-iv8},
      volume = {48},
      number = {Supplement{\_}4},
      issn = {0002-0729},
      journal = {Age and Ageing},
      doi = {10.1093/ageing/afz164.28} }
  • [article] bibtex
    Fülöp. Scheibler, H. Pfaff, C. Kowalski, und L. Ansmann, "Shared Decision Making in Brustzentren in NRW: Ergebnisse einer 10-Jahres-Trendanalyse" Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, vol. 147-148, pp. 97-102, 2019.
    @article{Scheibler.2019, abstract = {BACKGROUND Although shared decision making (SDM) has been gaining importance in German health services for some time now, the state of its implementation is still unknown. The aim of this study was to provide a valid trend analysis for SDM in breast care centres in the German federal state of North Rhine-Westphalia (NRW) for a period of 10 years. METHODS As part of an annual patient survey in breast care centres in NRW, two subscales of the Perceived Involvement in Care Scales (PICS) were used and analysed in multi-level models. RESULTS Data from nearly 40,000 patients could be analysed with consistently high response rates. In the observation period from 2006 to 2015 doctor facilitation and patient involvement increased on a scale from 1 to 4 of 3.1 to 3.4 and 2.6 to 2.8, respectively. CONCLUSIONS Despite the slight increases in the 10-year observation period a stable trend cannot be assumed. However, this study might be useful as a baseline for other studies on SDM implementation.},
      author = {Scheibler, F{\"u}l{\"o}p and Pfaff, Holger and Kowalski, Christoph and Ansmann, Lena},
      year = {2019},
      title = {Shared Decision Making in Brustzentren in NRW: Ergebnisse einer 10-Jahres-Trendanalyse},
      pages = {97--102},
      volume = {147-148},
      journal = {Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen},
      doi = {10.1016/j.zefq.2019.09.003},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31629688} }
  • [article] bibtex
    M. Schweda, "Medical gazes and meteorological metaphors: representations of dementia in contemporary motion pictures" Israel Journal of Health Policy Research, vol. 8, iss. 1, p. 18, 2019.
    @article{Schweda.2019,
      author = {Schweda, Mark},
      year = {2019},
      title = {Medical gazes and meteorological metaphors: representations of dementia in contemporary motion pictures},
      pages = {18},
      volume = {8},
      number = {1},
      issn = {2045-4015},
      journal = {Israel Journal of Health Policy Research},
      doi = {10.1186/s13584-018-0283-3} }
  • M. Spies, A. L. Brütt, und A. Buchholz, "Content comparison of guideline-recommended instruments used in treatment for alcohol use disorders" Disabil Rehabil, vol. 41, iss. 14, pp. 1682-1689, 2019.
    @article{Spies.2019,
      author = {Spies, M. and Br{\"u}tt, Anna Levke and Buchholz, Angela},
      year = {2019},
      title = {Content comparison of guideline-recommended instruments used in treatment for alcohol use disorders},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/29397779},
      pages = {1682--1689},
      volume = {41},
      number = {14},
      journal = {Disabil Rehabil},
      doi = {10.1080/09638288.2018.1433724} }
  • [article] bibtex
    S. A. K. Uthoff, L. Ansmann, und K. Wehkamp, "Ökonomische und medizinethische Ziele im Krankenhaus als Gegenstand des Medizinstudiums" Ethik in der Medizin, vol. 31, iss. 2, pp. 159-174, 2019.
    @article{Uthoff.2019,
      author = {Uthoff, Sarah Anna Katharina and Ansmann, Lena and Wehkamp, Karl-Heinz},
      year = {2019},
      title = {{\"O}konomische und medizinethische Ziele im Krankenhaus als Gegenstand des Medizinstudiums},
      pages = {159--174},
      volume = {31},
      number = {2},
      issn = {0935-7335},
      journal = {Ethik in der Medizin},
      doi = {10.1007/s00481-019-00524-7} }
  • [article] bibtex
    B. Engel, M. Esser, und M. Bleckwenn, "Piloting a blended-learning concept for integrating evidence-based medicine into the general practice clerkship" GMS Journal for Medical Education, vol. 36, iss. 6, p. 71, 2019.
    @article{Engel.2019, abstract = {Objective: The present study investigates the feasibility of the application of evidence-based medicine (EBM) procedures by students as part of practical training in general medicine through a newly developed blended-learning teaching concept. Methodology: This study describes the development, piloting and evaluation of a blended-learning concept for implementing EBM education as part of general practice training. Our concept consists of an online tutorial introducing the theoretical background, two classroom seminars for consolidation and practical exercises based on case studies. Following this, students were to apply their knowledge to real-life cases during their training. To evaluate the learning outcome, we have developed an evaluation tool based on the Fresno Test (Bonn Test). At the end of the seminar, students were invited to evaluate the concept. Results: A total of 35 students took part in the feasibility study and 27 Bonn tests were evaluated. All students achieved more than the pass mark required in the Bonn Test in the preparation of clinical case studies. Because of the differentiated assessment of learning outcomes in all categories of the 5A EBM process, difficulties in the translation process can be revealed by the Bonn test. As a result, the concept can be refined and improved continuously. In the evaluation, 74{\%} of the students rated the teaching concept {\textquotedbl}good{\textquotedbl} or {\textquotedbl}very good{\textquotedbl}. Conclusion: Overall, this study confirmed the feasibility of our EBM concept while demonstrating that students are able to apply the theoretical knowledge acquired to real-life settings. Further research with our concept is needed, especially at an earlier stage in the curriculum. Zielsetzung: Die vorliegende Arbeit pr{\"u}ft die Machbarkeit der praktischen Anwendung von Evidenzbasierter Medizin (EbM) durch Studenten w{\"a}hrend des Blockpraktikums (BP) im Fachgebiet Allgemeinmedizin durch ein neu entwickeltes Blended-Learning-Lehrkonzept.Methodik: Entwicklung, Pilotierung und Evaluation eines Blended-Learning Konzepts zur Einf{\"u}hrung der Lehre der EbM im BP der Allgemeinmedizin werden beschrieben. Das Konzept besteht aus einem Online-Modul zur Vermittlung der theoretischen Grundlagen der EbM anhand des 5A-Schritteprozesses, zwei Pr{\"a}senzseminaren zur Vertiefung der Inhalte und praktischen {\"U}bungen in Form von Fallbeispielen. Anschlie{\ss}end sollen die Studenten ihr erworbenes Wissen auf realen Patientenf{\"a}llen in der Praxiszeit ihres BP anwenden. Zur {\"U}berpr{\"u}fung des Lernerfolgs wurde auf Grundlage des Fresno Tests ein EbM-Evaluationsinstrument entwickelt -- der Bonn- Test. Am Ende des Seminars k{\"o}nnen die Studenten das Konzept in einer schriftlichen Evaluation bewerten und Verbesserungsvorschl{\"a}ge einbringen.Ergebnisse: Insgesamt nahmen 35 Studenten an der Machbarkeitsstudie teil, 27 Bonn-Tests konnten ausgewertet werden. Alle Studierende erreichten bei der Ausarbeitung klinischer Fallbeispiele mehr als die zum Bestehen ben{\"o}tigte Mindestpunktzahl im Bonn Test. Die differenzierte Leistungsdarstellung in den einzelnen Kategorien des 5-A-Schritteprozesses der EbM mit Hilfe des Bonn-Tests erm{\"o}glicht spezifische Schwierigkeiten bei der Translation von EbM-Wissen in die Praxis aufzudecken und das Lehrkonzept fortlaufend weiterzuentwickeln und zu verbessern. In der Evaluation bewerteten die Studenten das Lehrkonzept zu 74 {\%} mit {\glqq}gut{\grqq} oder {\glqq}sehr gut{\grqq}.Schlussfolgerungen: Insgesamt best{\"a}tigt die vorliegende Studie, dass die Erweiterung des Blockpraktikums im Fachbereich f{\"u}r Allgemeinmedizin um das neu entwickelte EbM-Modul machbar ist und die Studenten die erlernten Inhalte erfolgreich in der Praxis anwenden k{\"o}nnen. Weitere Untersuchungen des Lehrkonzepts, insbesondere zu einem fr{\"u}heren Zeitpunkt des Medizinstudiums, sind empfehlenswert.},
      author = {Engel, Bettina and Esser, Miriam and Bleckwenn, Markus},
      year = {2019},
      title = {Piloting a blended-learning concept for integrating evidence-based medicine into the general practice clerkship},
      pages = {Doc71},
      volume = {36},
      number = {6},
      journal = {GMS Journal for Medical Education},
      doi = {10.3205/zma001279},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6905357},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31844643} }
  • [article] bibtex
    N. Ernstmann, J. Herden, L. Weissbach, A. Karger, K. Hower, und L. Ansmann, "Prostate-specific health-related quality of life and patient-physician communication - A 3.5-year follow-up" Patient education and counseling, vol. 102, iss. 11, pp. 2114-2121, 2019.
    @article{Ernstmann.2019, abstract = {OBJECTIVE The aim of this study is to examine associations between prostate-specific health-related quality of life (HRQOL) and aspects of patient-physician communication in localized prostate cancer treatment. METHODS Data of patients with localized prostate cancer were collected at 6-month intervals over a 3.5-year period within a prospective, observational study (HAROW). Data collection comprised D'Amico risk categories, the Charlson Comorbidity Index, patient-physician communication (information, shared decision making, support, devotion), and prostate-specific HRQOL (incontinence aid, urinary symptoms, bowel symptoms, hormonal treatment-related symptoms, sexual functioning, sexual activity). Data of N = 1722 patients undergoing radical prostatectomy were analyzed by longitudinal multilevel analysis. RESULTS The mean patient age was 65 years; 31{\%} had a low risk and 38{\%} an intermediate risk of cancer growth and spread; 73{\%} had a Charlson Comorbidity Index of 0. Significant associations were found between prostate-specific HRQOL and shared decision making, support and devotion. Patient information was not significantly associated with aspects of prostate-specific HRQOL. CONCLUSION Patient reported long term outcomes are associated with aspects of patient-physician communication in prostate cancer patients. Patients feeling involved by their urologists experience less side effects of (surgical) treatment. PRACTICE IMPLICATIONS Special communication training programmes should be developed and implemented for urologists.},
      author = {Ernstmann, Nicole and Herden, Jan and Weissbach, Lothar and Karger, Andr{\'e} and Hower, Kira and Ansmann, Lena},
      year = {2019},
      title = {Prostate-specific health-related quality of life and patient-physician communication - A 3.5-year follow-up},
      pages = {2114--2121},
      volume = {102},
      number = {11},
      journal = {Patient education and counseling},
      doi = {10.1016/j.pec.2019.07.030},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31399225} }
  • [article] bibtex
    H. Fischer, R. Röhrig, und V. Thiemann, "A Generic IT Infrastructure for Identity Management and Pseudonymization in Small Research Projects with Heterogeneous and Distributed Data Sources Under Consideration of the GDPR" Studies in Health Technology and Informatics, vol. 264, pp. 1837-1838, 2019.
    @article{Fischer.2019, abstract = {Each year, millions of rescue operations occur in Germany. Despite rising numbers, there is a shortfall of systematic quality management (QM). Focusing on finding the required quality parameters, this work aims at linking heterogeneous and distributed data sources on the patient-level. Presented here is necessary IT infrastructure for linking patients' data records properly and efficiently. The focus of the IT infrastructure is to provide a lightweight and easy applicable solution with an utmost generic approach.},
      author = {Fischer, Hauke and R{\"o}hrig, Rainer and Thiemann, Volker},
      year = {2019},
      title = {A Generic IT Infrastructure for Identity Management and Pseudonymization in Small Research Projects with Heterogeneous and Distributed Data Sources Under Consideration of the GDPR},
      pages = {1837--1838},
      volume = {264},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      doi = {10.3233/SHTI190673},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31438368} }
  • [article] bibtex
    A. Gerka, C. Lins, M. Pfingsthorn, M. Eichelberg, S. M. Müller, C. Stolle, und A. Hein, "A Clustering-Based Approach to Determine a Standardized Statistic for Daily Activities of Elderly Living Alone" Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies (HealthInf), vol. 5, pp. 264-271, 2019.
    @article{Gerka.2019, abstract = {The modeling of behavior by monitoring activities of daily living allows caregivers to recognize early stages of dementia. Therefore, many monitoring systems were presented in recent years. In this work, we present a behavior modeling system that is based only on two adjustable parameters and provides a single standardized output statistic. Therefore, this system enhances the comparison of recent and future activity monitoring systems. The approach is comprised of three parts: First, the clustering of power plug data to detect time windows in which appliances are used regularly. Second, the calculation of a comparison Matrix. Third the test of change using the $\backslash$chi2-statistic. We tested this approach successfully in a seven-month field study with two healthy subjects. We showed that the $\backslash$chi2-statistic reflected how regular activities were performed and that one to two months, depending on the regularity of the performed activities, provide the necessary amount of reference data for our approach to work.},
      author = {Gerka, Alexander and Lins, Christian and Pfingsthorn, Max and Eichelberg, Marco and M{\"u}ller, Sebastian Matthias and Stolle, Christian and Hein, Andreas},
      year = {2019},
      title = {A Clustering-Based Approach to Determine a Standardized Statistic for Daily Activities of Elderly Living Alone},
      keywords = {$\backslash$chi2-statistic;Activities of Daily Living;Assisted Living;Behavior Modeling;Clustering;Dementia;QuoVadis},
      pages = {264--271},
      volume = {5},
      journal = {Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies (HealthInf)},
      doi = {10.5220/0007369302640271},
      file = {Gerka et al. - 2019 - A Clustering-Based Approach to Determine a Standardized Statistic for Daily Activities of Elderly Living Alone:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2019 - A Clustering-Based Approach to Determine a Standardized Statistic for Daily Activities of Elderly Living Alone.pdf:pdf} }
  • [article] bibtex
    S. E. Groß, H. Pfaff, M. Swora, L. Ansmann, U. Albert, und A. Groß-Kunkel, "Health disparities among breast cancer patients with/without disabilities in Germany" Disability and health journal, vol. 13, iss. 2, p. 100873, 2019.
    @article{Gro.2019, abstract = {BACKGROUND Prevalence and incidence of cancer are increasing in people with disability. Nevertheless, little is known about cancer care for people with disabilities. OBJECTIVE The goal of this study was to examine the quality of care of breast cancer patients with pre-existing disabilities regarding diagnosis and type of breast surgery in Germany. METHODS Within the framework of quality assurance of breast cancer centers, a patient survey was conducted by the University of Cologne. Survey data from 4626 newly-diagnosed breast cancer patients treated in 86 hospitals were analyzed using multilevel modeling. Data about socio-demographics, disability specific data as well as data about diagnosis and type of surgery were collected. RESULTS About 13{\%} (n = 568) of the patients indicated they had a pre-existing disability prior to their breast cancer. The majority of patients with disabilities have physical impairments (PI n = 385; 68.0{\%}) or sensory impairments (SI n = 131; 23.1{\%}). 16.7{\%} of the patients indicated they have a mental illness (MI n = 95; 16.7{\%}) and 8 patients indicated to have an intellectual disability (ID n = 8; 1.4{\%}). Patients with PI and SI are less often diagnosed for cancer through a mammography screening (OR PI = 0.70; p {\textless} 0.05; OR SI = 0.58; p {\textless} 0.05). Patients with PI are less likely to receive breast conserving treatment (OR = 0.58; p {\textless} 0.00) and more likely to have a mastectomy without reconstruction (OR = 1.96; p {\textless} 0.00) compared to patients without disabilities. CONCLUSION Our data show that there are differences in the frequency of cancer diagnosis through mammography screening and in surgery applied between breast cancer patients with and without disabilities.},
      author = {Gro{\ss},
      Sophie Elisabeth and Pfaff, Holger and Swora, Michael and Ansmann, Lena and Albert, Ute-Susann and Gro{\ss}-Kunkel, Anke},
      year = {2019},
      title = {Health disparities among breast cancer patients with/without disabilities in Germany},
      pages = {100873},
      volume = {13},
      number = {2},
      journal = {Disability and health journal},
      doi = {10.1016/j.dhjo.2019.100873},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31780299} }
  • [article] bibtex
    M. Groß, M. Pohl, O. Summ, P. Young, M. Winterholler, A. Weigel, und R. Röhrig, "Beatmung in neurologischen Organisationseinheiten in Deutschland" Der Nervenarzt, vol. 90, iss. 10, pp. 1037-1044, 2019.
    @article{Gro.2019b, abstract = {BACKGROUND Mechanical ventilation is provided for neurological patients in the following settings: in neurointensive care units, in centers providing weaning and early rehabilitation and in home mechanical ventilation. In the last decade there has been a~sharp rise in treatment and bed capacities for mechanically ventilated neurological patients in specialized centers in Germany in the areas of weaning and neurological neurosurgical early rehabilitation of ventilated patients. Neither the number of beds nor details about structures in these centers with respect to bed capacity, personnel and qualifications, equipment, treatment methods and concepts are known. OBJECTIVE The aim of this survey was to generate detailed numbers regarding structural criteria of specialized centers for mechanically ventilated neurology patients, regarding hospital beds, technical infrastructure, personnel and qualifications as well as treatment methods and concepts. MATERIAL AND METHODS An online survey with 48~questions on the type and size of the institution, structural criteria, equipment and personnel was developed and supported by the German Society for Neurology (DGN), the German Interdisciplinary Society of Out-of-Hospital Ventilation (DIGAB) and the German Society of Neurorehabilitation (DGNR). RESULTS A total of 63~centers took part in the survey and reported a total of 687 beds for mechanically ventilated neurological patients. Furthermore, they reported complex structures regarding personnel and qualifications, medical devices, methods and concepts but neurophysiological electrophysiology was the only technical method provided in all centers. Of the institutions 49{\%} (n = 27/55) provided the initiation of home mechanical ventilation, 18{\%} (n = 18/55) provided inpatient control of home mechanical ventilation, 9{\%} (n = 5/55) had an outpatient department for home mechanical ventilation and 18{\%} (n = 10/55) extracted data from home ventilators. CONCLUSION Mechanical ventilation in neurological units offers vast and complex treatment and bed capacities for severely ill patients in Germany. The structures are inhomogeneous and a consensus on specific criteria should be established. This is especially true for the treatment of patients needing out-of-hospital mechanical ventilation, also with respect to a possible weaning in the long-term duration of the disease.},
      author = {Gro{\ss},
      Martin and Pohl, Marcus and Summ, Oliver and Young, Peter and Winterholler, Martin and Weigel, Anette and R{\"o}hrig, Rainer},
      year = {2019},
      title = {Beatmung in neurologischen Organisationseinheiten in Deutschland},
      pages = {1037--1044},
      volume = {90},
      number = {10},
      journal = {Der Nervenarzt},
      doi = {10.1007/s00115-019-0701-y},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30963181} }
  • S. Hellmers, S. Fudickar, S. Lau, L. Elgert, R. Diekmann, J. Bauer, und A. Hein, "Measurement of the Chair Rise Performance of Older People Based on Force Plates and IMUs" Sensors, vol. 19, iss. 6, 2019.
    @article{Hellmers.2019, abstract = {An early detection of functional decline with age is important to start interventions at an early state and to prolong the functional fitness. In order to assure such an early detection, functional assessments must be conducted on a frequent and regular basis. Since the five time chair rise test (5CRT) is a well-established test in the geriatric field, this test should be supported by technology. We introduce an approach that automatically detects the execution of the chair rise test via an inertial sensor integrated into a belt. The system's suitability was evaluated via 20 subjects aged 72--89 years (78.2 $\pm$ 4.6 years) and was measured by a stopwatch, the inertial measurement unit (IMU), a Kinect$\backslash$textregistered camera and a force plate. A Multilayer Perceptrons-based classifier detects transitions in the IMU data with an F1-Score of around 94.8{\%}. Valid executions of the 5CRT are detected based on the correct occurrence of sequential movements via a rule-based model. The results of the automatically calculated test durations are in good agreement with the stopwatch measurements (correlation coefficient r = 0.93 (p {\textless} 0.001)). The analysis of the duration of single test cycles indicates a beginning fatigue at the end of the test. The comparison of the movement pattern within one person shows similar movement patterns, which differ only slightly in form and duration, whereby different subjects indicate variations regarding their performance strategies.},
      author = {Hellmers, Sandra and Fudickar, Sebastian and Lau, Sandra and Elgert, Lena and Diekmann, Rebecca and Bauer, J{\"u}rgen and Hein, Andreas},
      year = {2019},
      title = {Measurement of the Chair Rise Performance of Older People Based on Force Plates and IMUs},
      url = {http://www.mdpi.com/1424-8220/19/6/1370},
      volume = {19},
      number = {6},
      journal = {Sensors},
      doi = {10.3390/s19061370},
      file = {Hellmers et al. - 2019 - Measurement of the Chair Rise Performance of Older People Based on Force Plates and IMUs:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2019 - Measurement of the Chair Rise Performance of Older People Based on Force Plates and IMUs.pdf:pdf} }
  • [article] bibtex
    C. Heuser, A. Diekmann, N. Ernstmann, und L. Ansmann, "Patient participation in multidisciplinary tumour conferences in breast cancer care (PINTU): a mixed-methods study protocol" BMJ open, vol. 9, iss. 4, p. 024621, 2019.
    @article{Heuser.2019, abstract = {INTRODUCTION A central instrument of multidisciplinary care is the multidisciplinary tumour conference (MTC). In MTCs, diagnosis and treatment of cancer patients are discussed, and therapy recommendations are worked out. As we found previously, patients participate in MTCs in some breast cancer centres in the state of North Rhine-Westphalia, Germany. However, studies on risks and benefits of patient participation have not provided substantiated findings. Therefore, the study's objective is to analyse differences between MTCs with and without patient participation. METHODS AND ANALYSIS This is an exploratory mixed-methods study. MTCs in six breast and gynaecological cancer centres in North Rhine-Westphalia, Germany, are examined. MTCs will be conducted with and without patient participation. First, interviews with providers concentrating on the feasibility of patient participation and quality of decision-making will be carried out, transcribed and analysed by means of content analysis. Second, videotaped or audiotaped participatory observations in MTCs will be executed. Video data or transcribed audio data from video and audio recordings will be coded using the established {\textquotedbl}Observational Assessment Rating Scale{\textquotedbl} for MTCs and analysed by comparing centres with and without patient participation. Third, all patients will fill out a questionnaire before and after MTC, including questions on psychosocial situation, decision-making and expectations before and experiences after MTC. The questionnaire data will be analysed by means of descriptive and multivariate statistics and pre-post-differences within and between groups. ETHICS AND DISSEMINATION Consultation and a positive vote from the ethics committee of the Medical Faculty of the University of Cologne have been obtained. For all collected data, relevant data protection regulations will be adhered to. All personal identifiers from patients and providers will be pseudonymised, except video recordings. Dissemination strategies include a discussion with patients and providers in workshops about topics such as feasibility, risks and benefits of patient participation in MTCs. TRIAL REGISTRATION NUMBER DRKS00012552.},
      author = {Heuser, Christian and Diekmann, Annika and Ernstmann, Nicole and Ansmann, Lena},
      year = {2019},
      title = {Patient participation in multidisciplinary tumour conferences in breast cancer care (PINTU): a mixed-methods study protocol},
      pages = {e024621},
      volume = {9},
      number = {4},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2018-024621},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30962228},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500308} }
  • [article] bibtex
    C. Heuser, A. Diekmann, C. Kowalski, A. Enders, R. Conrad, H. Pfaff, L. Ansmann, und N. Ernstmann, "Health literacy and patient participation in multidisciplinary tumor conferences in breast cancer care: a multilevel modeling approach" BMC cancer, vol. 19, iss. 1, p. 330, 2019.
    @article{Heuser.2019b, abstract = {BACKGROUND Decisions made in multidisciplinary tumor conferences (MTC) that consider patient preferences result in better patient outcomes. Furthermore, it has been shown that in some breast cancer centers in Germany, patients participate in MTCs and that participation is associated with sociodemographic and breast cancer center-related factors. Health literacy (HL) has been shown to be predictive for individual health behavior and is an important prerequisite for patient participation in healthcare. However, so far nothing is known about the association between HL and MTC patient participation. To close this gap in research, we analyzed which patient characteristics affect participation in MTCs and whether participation varies between breast cancer centers. METHODS In a prospective, multicenter cohort study, newly diagnosed breast cancer patients were surveyed directly after surgery (T1) as well as 10 weeks (T2) and 40 weeks (T3) after surgery. After descriptive analysis, t-tests were conducted, correlations for independent variables were run, and logistic multilevel regression analysis was applied to estimate the association between patient participation in MTCs at T1 and HL (HLS-EU-Q16 [1]), sociodemographic and disease-related characteristics (n~= 863 patients) and the variation between breast cancer centers (n~= 43 centers). RESULTS Descriptive results show that 6.8{\%} of breast cancer patients took part in a MTC. The logistic multilevel regression model revealed that patients with an inadequately HL are less likely to participate in MTCs (OR = 0.31, 95{\%}-CI = 0.1-0.9, Pseudo-R2~= 0.06), and participation is dependent on the breast cancer center (ICC = 0.161). CONCLUSIONS These findings are the first to show significant differences in HL and patient participation in MTCs in a large sample of breast cancer patients. In future research on patient participation in MTCs and HL, questions concerning the organization, communication and decision-making in MTCs with and without patient participation have to be addressed, and patient and provider perspectives must be equally considered. TRIAL REGISTRATION Database Health Services Research, VfD{\_}PIAT{\_}12{\_}001630 , registered prospectively on 01.03.2012.},
      author = {Heuser, Christian and Diekmann, Annika and Kowalski, Christoph and Enders, Anna and Conrad, Rupert and Pfaff, Holger and Ansmann, Lena and Ernstmann, Nicole},
      year = {2019},
      title = {Health literacy and patient participation in multidisciplinary tumor conferences in breast cancer care: a multilevel modeling approach},
      pages = {330},
      volume = {19},
      number = {1},
      journal = {BMC cancer},
      doi = {10.1186/s12885-019-5546-z},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30961598},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454712} }
  • [article] bibtex
    U. Hoffmann, J. Koschate, H. Appell Coriolano, U. Drescher, L. Thieschäfer, D. Dumitrescu, und A. Werner, "Adaptation of Systemic and Pulmonary Circulation to Acute Changes in Gravity and Body Position" Aerospace medicine and human performance, vol. 90, iss. 8, pp. 688-695, 2019.
    @article{Hoffmann.2019, abstract = {INTRODUCTION: Changes in gravity or body position provoke changes in hydrostatic pressure in the arterial system and in venous return. Potential asymmetries between left (QLV) and right ventricular (QRV) cardiac output during transient gravity changes were investigated. It was hypothesized that blood volume is temporarily stored in the pulmonary vessels, with amount and duration depending on the level and directions of gravity.METHODS: Eight healthy, male subjects (32 $\pm$ 3 yr, 182 $\pm$ 7 cm, 82 $\pm$ 6 kg) were tested on a tilt seat (TS), in a long arm human centrifuge (laHC), and during parabolic flights (PF). The gravitational changes during PF were reconstructed by changing gravity in a laHC and different body positions on a TS. All participants were tested in the seated, resting position. Heart rate and blood pressure were recorded continuously and QLV was calculated, applying the Modelflow Algorithm. Gas exchange was measured breath-by-breath. QRV was calculated from these data according to the Fick Principle. Four sequences were superimposed and analyzed by ANOVA with the factors Time, Ventricle (QRV, QLV), and Mode (TS, PF, laHC).RESULTS: After reductions in gravity QRV and QLV were transiently desynchronized. ANOVA showed no main effect for Mode, but significant changes were found for Time and Ventricle and all interactions.DISCUSSION: Phases of reduced gravity seem to lead to transiently increased storage of blood volume inside the pulmonary vascular system. A more detailed understanding of these mechanisms might help to describe the compliance of the pulmonary vascular system in diseases of the pulmonary circulation.Hoffmann U, Koschate J, Appell Coriolano H-J, Drescher U, Thiesch{\"a}fer L, Dumitrescu D, Werner A. Adaptation of systemic and pulmonary circulation to acute changes in gravity and body position. Aerosp Med Hum Perform. 2019; 90(8):688-695.},
      author = {Hoffmann, Uwe and Koschate, Jessica and {Appell Coriolano},
      Hans-Joachim and Drescher, Uwe and Thiesch{\"a}fer, Lutz and Dumitrescu, Daniel and Werner, Andreas},
      year = {2019},
      title = {Adaptation of Systemic and Pulmonary Circulation to Acute Changes in Gravity and Body Position},
      pages = {688--695},
      volume = {90},
      number = {8},
      journal = {Aerospace medicine and human performance},
      doi = {10.3357/AMHP.5300.2019},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31331418} }
  • [article] bibtex
    F. Hoffmann und K. Allers, "Dying in hospital among nursing home residents with and without dementia in Germany" Arch Gerontol Geriatr, vol. 82, pp. 293-298, 2019.
    @article{Hoffmann.2019d, abstract = {OBJECTIVES: Nursing home residents (NHR) often suffer from dementia. As end-of-life care of NHR with dementia and without might differ, our aim was to investigate patterns of in-hospital deaths in NHR with and without dementia. DESIGN: Retrospective observational study. SETTING: German nursing homes. PARTICIPANTS: Deceased NHR. MEASUREMENTS: Using data of a large German health insurance fund, we included NHR aged 65+ years who died between January 1, 2010, and December 31, 2014. We assessed proportions of in-hospital deaths stratified by dementia status as well as by age, sex, level of care and length of stay. Multiple logistic regression models were applied to explore the association of these variables with in-hospital death. RESULTS: Data on 67,328 decedents were included (mean age 85.3 years, 69.8{\%} female), of whom 43.1{\%} suffered from dementia. Overall, 29.5{\%} died in hospital, with similar figures found for those with dementia (29.2{\%}) and those without (29.8{\%}). Differences between NHR with and without dementia were noticeable regarding age and length of stay. In those with dementia, the proportion of in-hospital deaths decreased linearly with age from 37.0{\%}-20.2{\%} (65-74 to 95+ years). These results are supported by the multivariate analyses. The terminal hospital stay was up to 3 days in 32.6{\%}. This length did not differ by dementia status. CONCLUSIONS: Germany has a high proportion of NHR in-hospital deaths. Surprisingly, we found no differences in these figures between NHR with and without dementia, although predictors for in-hospital death seem to differ between these groups.},
      author = {Hoffmann, Falk and Allers, Katharina},
      year = {2019},
      title = {Dying in hospital among nursing home residents with and without dementia in Germany},
      keywords = {*End-of-life care;*Health services research;*Hospital use;*Long-term care;*Nursing Homes;*Nursing Homes/statistics {\&} numerical data;Aged;Aged, 80 and over;Dementia/*mortality;Female;Hospital Mortality;Humans;Logistic Models;Male;Retrospective Studies},
      pages = {293--298},
      volume = {82},
      issn = {0167-4943},
      journal = {Arch Gerontol Geriatr},
      doi = {10.1016/j.archger.2019.03.013} }
  • [article] bibtex
    K. Hower, V. Vennedey, H. A. Hillen, L. Kuntz, S. Stock, H. Pfaff, und L. Ansmann, "Implementation of patient-centred care: which organisational determinants matter from decision maker's perspective? Results from a qualitative interview study across various health and social care organisations" BMJ open, vol. 9, iss. 4, p. 027591, 2019.
    @article{Hower.2019, abstract = {OBJECTIVES Health and social care systems, organisations and providers are under pressure to organise care around patients' needs with constrained resources. To implement patient-centred care (PCC) successfully, barriers must be addressed. Up to now, there has been a lack of comprehensive investigations on possible determinants of PCC across various health and social care organisations (HSCOs). Our qualitative study examines determinants of PCC implementation from decision makers' perspectives across diverse HSCOs. DESIGN Qualitative study of n=24 participants in n=20 semistructured face-to-face interviews conducted from August 2017 to May 2018. SETTING AND PARTICIPANTS Decision makers were recruited from multiple HSCOs in the region of the city of Cologne, Germany, based on a maximum variation sampling strategy varying by HSCOs types. OUTCOMES The qualitative interviews were analysed using an inductive and deductive approach according to qualitative content analysis. The Consolidated Framework for Implementation Research was used to conceptualise determinants of PCC. RESULTS Decision makers identified similar determinants facilitating or obstructing the implementation of PCC in their organisational contexts. Several determinants at the HSCO's inner setting and the individual level (eg, communication among staff and well-being of employees) were identified as crucial to overcome constrained financial, human and material resources in order to deliver PCC. CONCLUSIONS The results can help to foster the implementation of PCC in various HSCOs contexts. We identified possible starting points for initiating the tailoring of interventions and implementation strategies and the redesign of HSCOs towards more patient-centredness.},
      author = {Hower, Kira and Vennedey, Vera and Hillen, Hendrik Ansgar and Kuntz, Ludwig and Stock, Stephanie and Pfaff, Holger and Ansmann, Lena},
      year = {2019},
      title = {Implementation of patient-centred care: which organisational determinants matter from decision maker's perspective? Results from a qualitative interview study across various health and social care organisations},
      pages = {e027591},
      volume = {9},
      number = {4},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2018-027591},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500213},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30940764} }
  • [article] bibtex
    K. Hower, H. Pfaff, C. Kowalski, M. Wensing, und L. Ansmann, "Measuring change attitudes in health care organizations" Journal of health organization and management, vol. 33, iss. 3, pp. 266-285, 2019.
    @article{Hower.2019g, abstract = {PURPOSE Measuring attitudes of healthcare providers and managers toward change in health care organizations (HCOs) has been of widespread interest. The purpose of this paper is to evaluate the psychometric characteristics and usability of an abbreviated German version of the Change Attitude Scale. DESIGN/METHODOLOGY/APPROACH The Change Attitude Scale was used in a survey of healthcare providers and managers in German hospitals after the implementation of a breast cancer center concept. Reliability analysis, confirmatory factor analysis, structural equation modeling and bivariate analysis were conducted. FINDINGS Data from 191 key persons in 82 hospitals were analyzed. The item-scale structure produced an acceptable model fit. Convergent validity was shown by significant correlations with measures of individuals' general opinions of the breast center concept. A non-significant correlation with a scale measuring the hospital's hierarchical structure of leadership verified discriminant validity. The interaction of key persons' change attitude and hospitals' change performance through change culture as a mediator supported the predictive validity. RESEARCH LIMITATIONS/IMPLICATIONS The study found general support for the validity and usability of a short version of the German Change Attitude Scale. PRACTICAL IMPLICATIONS Since attitudes toward change influence successful implementation, the survey may be used to tailor the design of implementation programs and to create a sustainable culture of high readiness for change. ORIGINALITY/VALUE This is the first study finding that a short instrument can be used to measure attitudes toward change among healthcare providers and managers in HCOs.},
      author = {Hower, Kira and Pfaff, Holger and Kowalski, Christoph and Wensing, Michel and Ansmann, Lena},
      year = {2019},
      title = {Measuring change attitudes in health care organizations},
      pages = {266--285},
      volume = {33},
      number = {3},
      journal = {Journal of health organization and management},
      doi = {10.1108/JHOM-06-2018-0177},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31122117} }
  • [article] bibtex
    N. Koensgen, T. Rombey, K. Allers, T. Mathes, F. Hoffmann, und D. Pieper, "Comparison of non-Cochrane systematic reviews and their published protocols: differences occurred frequently but were seldom explained" Journal of Clinical Epidemiology, vol. 110, pp. 34-41, 2019.
    @article{Koensgen.2019, abstract = {OBJECTIVE: To quantify the prevalence of differences in the reported methods between non-Cochrane systematic reviews (SRs) and their protocols and the extent to which these were reported and explained. STUDY DESIGN AND SETTING: We searched MEDLINE and Embase to identify protocols of non-Cochrane SRs published in 2012 and 2013. Using various methods, we searched for their corresponding SRs up to December 2016. The SRs and protocols were compared with respect to the methods-related {\textquotedbl}Preferred Reporting Items for Systematic review and Meta-Analysis Protocols{\textquotedbl} (PRISMA-P). RESULTS: We included 80 SRs and their protocols. Almost all SRs (92.5{\%}) differed from their protocols in at least one of the methods-related PRISMA-P items (no. 7-17) and their subcategories. Half the SRs (48.8{\%}) had a major difference in at least one item. On average, each SR differed from its protocol in 3.2 items, of which one comprised a major difference. Only 10{\%} of all differences were reported in the SR, two-thirds with an explanation (7.0{\%} in total). CONCLUSION: The reporting quality and transparency of non-Cochrane SRs requires further improvement. Authors should report and explain all important changes made to the protocol in the SR publication. The updated PRISMA statement should include guidance regarding this matter.},
      author = {Koensgen, N. and Rombey, Tanja and Allers, Katharina and Mathes, T. and Hoffmann, Falk and Pieper, Dawid},
      year = {2019},
      title = {Comparison of non-Cochrane systematic reviews and their published protocols: differences occurred frequently but were seldom explained},
      keywords = {*Meta-Analysis as Topic;*Methodology;*prisma;*Protocol;*Quality Control;*Reporting quality;*Systematic review;*Systematic Reviews as Topic;*Transparency;Humans;Needs Assessment;Publications;United States},
      pages = {34--41},
      volume = {110},
      issn = {0895-4356},
      journal = {Journal of Clinical Epidemiology},
      doi = {10.1016/j.jclinepi.2019.02.012} }
  • [article] bibtex
    J. Koschate, L. Gerlich, V. Wirtz, L. Thieschäfer, U. Drescher, und U. Hoffmann, "Cardiorespiratory kinetics: comparisons between athletes with different training habits" European journal of applied physiology, vol. 119, iss. 8, pp. 1875-1883, 2019.
    @article{Koschate.2019b, abstract = {PURPOSE Fast muscular oxygen uptake ([Formula: see text]) kinetics are limiting factors for high exercise capacities. It is hypothesized that [Formula: see text] and heart rate (HR) kinetics would be faster in individuals, performing long-distance endurance training (CONT) compared with athletes performing predominantly interval-based sports (INT). METHODS 17 subjects (INT: n = 7, 24 $\pm$ 5~years, 183 $\pm$ 7~cm, 85 $\pm$ 10~kg, 6 $\pm$ 3~h of training per week, CONT: n = 10, 37 $\pm$ 7~years, 175 $\pm$ 9~cm, 69 $\pm$ 10~kg, 6 $\pm$ 3~h of training per week) completed a treadmill work rate (WR) protocol with pseudo-randomized WR changes with velocities of 6.5 and 9.5~km~h-1. [Formula: see text]O2musc and the respective kinetics were estimated from the measured pulmonary oxygen uptake and HR combined with a circulatory model. Kinetics information were calculated using time series analysis. Higher maxima of the cross-correlation function (CCF) of WR and the respective parameter ([Formula: see text], HR) indicate faster kinetics responses. RESULTS The kinetics of HR (INT: 0.23 $\pm$ 0.04 vs. CONT: 0.42 $\pm$ 0.18; P = 0.001), [Formula: see text]O2pulm (0.30 $\pm$ 0.05 vs. 0.53 $\pm$ 0.20; P = 0.005) and [Formula: see text]O2musc (0.31 $\pm$ 0.06 vs. 0.53 $\pm$ 0.16; P = 0.005) were significantly slower in INT compared with the CONT athletes. CONCLUSIONS It seems that at least in the long-term CONT exercise, training without the need of changing intensities is favorable for fast [Formula: see text]O2 and HR kinetics compared with INT exercise including frequently changing intensities.},
      author = {Koschate, Jessica and Gerlich, Laura and Wirtz, Veronika and Thiesch{\"a}fer, Lutz and Drescher, Uwe and Hoffmann, Uwe},
      year = {2019},
      title = {Cardiorespiratory kinetics: comparisons between athletes with different training habits},
      pages = {1875--1883},
      volume = {119},
      number = {8},
      journal = {European journal of applied physiology},
      doi = {10.1007/s00421-019-04176-9},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31227908} }
  • [article] bibtex
    J. Koschate, V. Cettolo, U. Hoffmann, und M. P. Francescato, "Breath-by-breath oxygen uptake during running: Effects of different calculation algorithms" Experimental physiology, vol. 104, iss. 12, pp. 1829-1840, 2019.
    @article{Koschate.2019c, abstract = {NEW FINDINGS What is the central question of this study? Breath-by-breath gas exchange analysis during treadmill exercise can be disturbed by different breathing patterns depending on cadence, and the flow sensor might be subjected to variable mechanical stress. It is still unclear whether the outcomes of the gas exchange algorithms can be affected by running at different speeds. What is the main finding and its importance? Practically, the three investigated breath-by-breath algorithms ('Wessel', 'expiration-only' and 'independent breath') provided similar average gas exchange values for steady-state conditions. The 'independent breath' algorithm showed the lowest breath-by-breath fluctuations in the gas exchange data compared with the other investigated algorithms, both at steady state and during incremental exercise. ABSTRACT Recently, a new breath-by-breath gas exchange calculation algorithm (called 'independent breath') was proposed. In the present work, we aimed to compare the breath-by-breath O2 uptake ( V̇O2 ) values assessed in healthy subjects undergoing a running protocol, as calculated applying the 'independent breath' algorithm or two other commonly used algorithms. The traces of respiratory flow, O2 and CO2 fractions, used by the calculation algorithms, were acquired at the mouth on 17 volunteers at rest, during running on a treadmill at 6.5 and 9.5~km~h-1 , and thereafter up to volitional fatigue. Within-subject averages and standard deviations of breath-by-breath V̇O2 were calculated for steady-state conditions; the V̇O2 data of the incremental phase were analysed by means of linear regression, and their root mean square was assumed to be an index of the breath-by-breath fluctuations. The average values obtained with the different algorithms were significantly different (P~{\textless}~0.001); nevertheless, from a practical point of view the difference could be considered 'small' in all the investigated conditions (effect size~{\textless}0.3). The standard deviations were significantly lower for the 'independent breath' algorithm (post hoc contrasts, P~{\textless}~0.001), and the slopes of the relationships with the corresponding data yielded by the other algorithms were {\textless}0.70. The root mean squares of the linear regressions calculated for the incremental phase were also significantly lower for the 'independent breath' algorithm, and the slopes of the regression lines with the corresponding values obtained with the other algorithms were~{\textless}0.84. In conclusion, the 'independent breath' algorithm yielded the least breath-by-breath O2 uptake fluctuation, both during steady-state exercise and during incremental running.},
      author = {Koschate, Jessica and Cettolo, Valentina and Hoffmann, Uwe and Francescato, Maria Pia},
      year = {2019},
      title = {Breath-by-breath oxygen uptake during running: Effects of different calculation algorithms},
      pages = {1829--1840},
      volume = {104},
      number = {12},
      journal = {Experimental physiology},
      doi = {10.1113/EP087916},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31583757} }
  • [article] bibtex
    C. Kowalski, K. Blohm, S. Weiß, M. Pfingsthorn, P. Gliesche, und A. Hein, "Multi low-resolution infrared sensor setup for privacy-preserving unobtrusive indoor localization" ICT4AWE 2019 - Proceedings of the 5th International Conference on Information and Communication Technologies for Ageing Well and e-Health, iss. Ict4awe, pp. 183-188, 2019.
    @article{Kowalski.2019, abstract = {The number of home intensive care patients is increasing while the number of nursing staff is decreasing at the same time. To counteract this problem, it is necessary to take a closer look at safety-critical scenarios such as long-term home ventilation to provide relief. One possibility for support in this case is the exact localization of the affected person and the caregiver. A wide variety of sensors can be used to remedy this problem. Since the privacy of the patient should not be disturbed, it is important to find unobtrusive solutions. For this specific application, low-resolution infrared sensors - which are unable to invade the patient's privacy due to the low amount of sensor data information - can be used. The objective of this work is to create a basis for an inexpensive, privacy-preserving indoor localization system through the use of multiple infrared sensors, which can be for example used to support long-term home ventilated patients. The results show that such localization is possible by utilizing a support vector machine for classification. For the described scenario, a specific sensor layout was chosen to ensure the highest possible area coverage with a minimum amount of sensor installations.},
      author = {Kowalski, Christian and Blohm, Kolja and Wei{\ss},
      Sebastian and Pfingsthorn, Max and Gliesche, Pascal and Hein, Andreas},
      year = {2019},
      title = {Multi low-resolution infrared sensor setup for privacy-preserving unobtrusive indoor localization},
      keywords = {Classification;Health Monitoring;Indoor Localization;Multiple Infrared Sensors},
      pages = {183--188},
      number = {Ict4awe},
      journal = {ICT4AWE 2019 - Proceedings of the 5th International Conference on Information and Communication Technologies for Ageing Well and e-Health},
      doi = {10.5220/0007694601830188},
      file = {Kowalski et al. - 2019 - Multi low-resolution infrared sensor setup for privacy-preserving unobtrusive indoor localization:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Kowalski et al. - 2019 - Multi low-resolution infrared sensor setup for privacy-preserving unobtrusive indoor localization.pdf:pdf} }
  • J. L. Magaard, T. Seeralan, A. De, H. Schulz, und A. L. Brütt, "Depressionsbehandlung aus Betroffenensicht - Eine qualitative Analyse der subjektiven Behandlungsvorstellungen uber Psychotherapie und hausärztliche Versorgung von Menschen mit Depressionen" Psychiatr Prax, vol. 46, iss. 5, pp. 268-273, 2019.
    @article{Magaard.2019,
      author = {Magaard, J. L. and Seeralan, T. and De, A. and Schulz, H. and Br{\"u}tt, Anna Levke},
      year = {2019},
      title = {Depressionsbehandlung aus Betroffenensicht - Eine qualitative Analyse der subjektiven Behandlungsvorstellungen uber Psychotherapie und haus{\"a}rztliche Versorgung von Menschen mit Depressionen},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/30508873},
      pages = {268--273},
      volume = {46},
      number = {5},
      issn = {0303-4259},
      journal = {Psychiatr Prax},
      doi = {10.1055/a-0787-6956} }
  • [article] bibtex
    V. Mann, F. Limberg, S. T. W. Mann, S. Little, M. Müller, M. Sander, und R. Röhrig, "Routineerhalt beim Umgang mit extraglottischen Atemwegen im Rettungsdienst: Effektivität und Nachhaltigkeit einer simulatorbasierten Ausbildung : Eine prospektive 2\hbox-zeitige Simulatorstudie" Medizinische Klinik, Intensivmedizin und Notfallmedizin, vol. 114, iss. 6, pp. 541-551, 2019.
    @article{Mann.2019, abstract = {OBJECTIVE For emergency medicine personnel (EMP), there is little evidence concerning the adequate timing for refresher courses to maintain routine in the application of extraglottic airways. The aim of this study was to evaluate the efficacy and long-term results of a~simulator-based education concept teaching the basic airway management skills with extraglottic airways for EMP and also to draw conclusions concerning the adequate time interval for refresher courses. METHODS By use of an explorative, prospective simulator-study with nonphysician EMP, airway management skills using the Larynxmaske Supreme{\circledR} (LMA{\hbox{-}}S) after an introduction lecture were examined. The application of an endotracheal tube (ETT) served as control. Time for preparation of the airway devices, insertion success, and resulting apnea time were assessed immediately after the first introduction lecture (t1) and unannounced 9-12~months thereafter (t2). RESULTS Comparison of the times for preparation of the LMA{\hbox{-}}S at t1 and t2 demonstrated similar results. After the introduction lecture, all paramedics were able to insert the LMA{\hbox{-}}S successfully after maximal 2~attempts; 9-12~months later success rates with the LMA{\hbox{-}}S were unchanged. Apnea time during airway management was shorter with the LMA{\hbox{-}}S compared to the ETT (p {\textless} 0.01). Times needed for preparation of the airway devices were similar. CONCLUSION The results of this simulator study indicate that a~standardized introduction lecture is appropriate to ensure long-lasting procedural skills up to 12~months, so that subsequent refresher courses in basic airway management with the LMA{\hbox{-}}S once a~year may be adequate. A~simulator-based education in basic airway management skills with extraglottic airways is recommended for facilitation of further clinical education according to the current guidelines.},
      author = {Mann, V. and Limberg, F. and Mann, S. T. W. and Little, S. and M{\"u}ller, M. and Sander, M. and R{\"o}hrig, Rainer},
      year = {2019},
      title = {Routineerhalt beim Umgang mit extraglottischen Atemwegen im Rettungsdienst: Effektivit{\"a}t und Nachhaltigkeit einer simulatorbasierten Ausbildung : Eine prospektive 2{\hbox{-}}zeitige Simulatorstudie},
      pages = {541--551},
      volume = {114},
      number = {6},
      journal = {Medizinische Klinik, Intensivmedizin und Notfallmedizin},
      doi = {10.1007/s00063-018-0429-7},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29644401} }
  • L. Pfaller und M. Schweda, "Excluded from the Good Life? An Ethical Approach to Conceptions of Active Ageing" Social Inclusion, vol. 7, iss. 3, p. 10, 2019.
    @article{Pfaller.2019,
      author = {Pfaller, Larissa and Schweda, Mark},
      year = {2019},
      title = {Excluded from the Good Life? An Ethical Approach to Conceptions of Active Ageing},
      url = {https://www.cogitatiopress.com/socialinclusion/article/view/1918},
      pages = {10},
      volume = {7},
      number = {3},
      issn = {2183-2803},
      journal = {Social Inclusion},
      doi = {10.17645/si.v7i3.1918} }
  • [article] bibtex
    R. Quinzler, M. H. Freitag, B. Wiese, M. Beyer, H. Brenner, A. Dahlhaus, A. Döring, T. Freund, M. Heier, H. Knopf, M. Luppa, J. Prokein, S. G. Riedel-Heller, I. Schäfer, C. Scheidt-Nave, M. Scherer, B. Schöttker, J. Szecsenyi, P. Thürmann, H. van den Bussche, J. Gensichen, und W. E. Haefeli, "A novel superior medication-based chronic disease score predicted all-cause mortality in independent geriatric cohorts" Journal of Clinical Epidemiology, vol. 105, pp. 112-124, 2019.
    @article{Quinzler.2019, abstract = {OBJECTIVES On the basis of current treatment guidelines, we developed and validated a medication-based chronic disease score (medCDS) and tested its association with all-cause mortality of older outpatients. STUDY DESIGN AND SETTING Considering the most prevalent chronic diseases in the elderly German population, we compiled a list of evidence-based medicines used to treat these disorders. Based on this list, a score (medCDS) was developed to predict mortality using data of a large longitudinal cohort of older outpatients (training sample; MultiCare Cohort Study). By assessing receiver-operating characteristics (ROC) curves, the performance of medCDS was then confirmed in independent cohorts (ESTHER, KORA-Age) of community-dwelling older patients and compared with already existing medication-based scores and a score using selected anatomical-therapeutic-chemical (ATC) codes. RESULTS The final medCDS score had an ROC area under the curve (AUC) of 0.73 (95{\%} CI 0.70-0.76). In the validation cohorts, its ROC AUCs were 0.79 (0.76-0.82, KORA-Age) and 0.74 (0.71-0.78, ESTHER), which were superior to already existing medication-based scores (RxRisk, CDS) and scores based on pharmacological ATC code subgroups (ATC3) or age and sex alone (Age{\&}Sex). CONCLUSIONS A new medCDS, which is based on actual treatment standards, predicts mortality of older outpatients significantly better than already existing scores.},
      author = {Quinzler, Renate and Freitag, Michael H. and Wiese, Birgitt and Beyer, Martin and Brenner, Hermann and Dahlhaus, Anne and D{\"o}ring, Angela and Freund, Tobias and Heier, Margit and Knopf, Hildtraud and Luppa, Melanie and Prokein, Jana and Riedel-Heller, Steffi G. and Sch{\"a}fer, Ingmar and Scheidt-Nave, Christa and Scherer, Martin and Sch{\"o}ttker, Ben and Szecsenyi, Joachim and Th{\"u}rmann, Petra and {van den Bussche},
      Hendrik and Gensichen, Jochen and Haefeli, Walter E.},
      year = {2019},
      title = {A novel superior medication-based chronic disease score predicted all-cause mortality in independent geriatric cohorts},
      pages = {112--124},
      volume = {105},
      issn = {0895-4356},
      journal = {Journal of Clinical Epidemiology},
      doi = {10.1016/j.jclinepi.2018.09.004},
      file = {Quinzler, Freitag et al. 2019 - A novel superior medication-based chronic:V\:\\53_Publikationen\\Literatur DVF 2020-11-13\\Citavi Attachments\\Quinzler, Freitag et al. 2019 - A novel superior medication-based chronic.pdf:pdf} }
  • [article] bibtex
    M. Wilken, D. Hüske-Kraus, und R. Röhrig, "Alarm Fatigue: Using Alarm Data from a Patient Data Monitoring System on an Intensive Care Unit to Improve the Alarm Management" Studies in Health Technology and Informatics, vol. 267, pp. 273-281, 2019.
    @article{Wilken.2019, abstract = {Excessive numbers of clinical alarms reduce the awareness of caregivers. Frequent alarms, many of which are non-actionable, can lead to cognitive overload, stress, and desensitization to alarms, called {\textquotedbl}Alarm Fatigue{\textquotedbl},
      which can severely impact patient safety. Due to the multifactorial nature of excessive alarming quantitative data about many facets of alarm generation and management are required in order to tackle the problem efficiently and effectively. Since there is no system available which would provide said data, we set out to develop one in the form of a data warehouse based on a thorough understanding of clinicians' needs. The developed system answers the users' needs in terms of readily providing them information on a daily basis, but also serves as a data source for further research. Further work is needed to include alarm sources from outside the patient monitoring infrastructure.},
      author = {Wilken, Marc and H{\"u}ske-Kraus, Dirk and R{\"o}hrig, Rainer},
      year = {2019},
      title = {Alarm Fatigue: Using Alarm Data from a Patient Data Monitoring System on an Intensive Care Unit to Improve the Alarm Management},
      pages = {273--281},
      volume = {267},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      doi = {10.3233/SHTI190838},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31483282} }
  • [article] bibtex
    A. Zinkevich, S. A. K. Uthoff, J. Boenisch, S. K. Sachse, T. Bernasconi, und L. Ansmann, "Complex intervention in augmentative and alternative communication (AAC) care in Germany: a study protocol of an evaluation study with a controlled mixed-methods design" BMJ open, vol. 9, iss. 8, p. 029469, 2019.
    @article{Zinkevich.2019, abstract = {INTRODUCTION The current practice of service delivery in Germany for people with complex communication needs (CCN) who are in need of augmentative and alternative communication (AAC) is characterised by diverse problems, including a lack of clarity in the responsibilities of the service providers involved. To address these issues a new service delivery model has been put in place, implemented in three AAC counselling centres for patients with a particular health insurance across Germany. The implementation of a new service delivery model aims to improve individualised service delivery. The model goes beyond standard care by adding case management, counselling, AAC training and, if needed, AAC therapy. This study aims to evaluate the effectiveness of this complex intervention. METHODS AND ANALYSIS In consideration of the complexity of the new service delivery model, formative and summative evaluation will be conducted. The formative evaluation will provide data based on qualitative and quantitative assessments of the competences and perspectives of all involved stakeholders, including a proxy measurement of persons with CCN. The summative evaluation will include a controlled study design as the new service delivery model will be compared against the service delivery in an existing contract and against data gathered from caregivers of AAC users provided with standard care. With the exception of the individual interviews the data will be collected from proxies-that is, informal and formal caregivers. ETHICS AND DISSEMINATION Data collection, storage and evaluation meet the currently valid data protection regulations. Consultation by the responsible data protection officer of the Oldenburg Medical School and a positive vote from its Ethics Committee were obtained prior to the start of the study. Dissemination strategies include the presentation of the obtained data and results in the form of publications and at conferences. TRIAL REGISTRATION NUMBER DRKS00013628.},
      author = {Zinkevich, Anna and Uthoff, Sarah Anna Katharina and Boenisch, Jens and Sachse, Stefanie Kal{\'e}n and Bernasconi, Tobias and Ansmann, Lena},
      year = {2019},
      title = {Complex intervention in augmentative and alternative communication (AAC) care in Germany: a study protocol of an evaluation study with a controlled mixed-methods design},
      pages = {e029469},
      volume = {9},
      number = {8},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2019-029469},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31467052},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720491} }
  • [article] bibtex
    S. Andrich, M. Ritschel, G. Meyer, F. Hoffmann, A. Stephan, M. Baltes, J. Blessin, K. Jobski, A. M. Fassmer, B. Haastert, V. Gontscharuk, W. Arend, L. Theunissen, D. Colley, R. Hinze, S. Thelen, P. Fuhrmann, C. G. G. Sorg, J. Windolf, C. J. Rupprecht, und A. Icks, "Healthcare provision, functional ability and quality of life after proximal femoral fracture - 'ProFem': Study protocol of a population-based, prospective study based on individually linked survey and statutory health insurance data" BMJ open, vol. 9, iss. 6, p. 028144, 2019.
    @article{Andrich.2019, abstract = {INTRODUCTION: Proximal femoral fractures (PFF) are among the most frequent fractures in older people. However, the situation of people with a PFF after hospital discharge is poorly understood. Our aim is to (1) analyse healthcare provision, (2) examine clinical and patient-reported outcomes (PROs), (3) describe clinical and sociodemographic predictors of these and (4) develop an algorithm to identify subgroups with poor outcomes and a potential need for more intensive healthcare. METHODS AND ANALYSIS: This is a population-based prospective study based on individually linked survey and statutory health insurance (SHI) data. All people aged minimum 60 years who have been continuously insured with the AOK Rheinland/Hamburg and experience a PFF within 1 year will be consecutively included (SHI data analysis). Additionally, 700 people selected randomly from the study population will be consecutively invited to participate in the survey. Questionnaire data will be collected in the participants' private surroundings at 3, 6 and 12 months after hospital discharge. If the insured person considers themselves to be only partially or not at all able to take part in the survey, a proxy person will be interviewed where possible. SHI variables include healthcare provision, healthcare costs and clinical outcomes. Questionnaire variables include information on PROs, lifestyle characteristics and socioeconomic status. We will use multiple regression models to estimate healthcare processes and outcomes including mortality and cost, investigate predictors, perform non-responder analysis and develop an algorithm to identify vulnerable subgroups. ETHICS AND DISSEMINATION: The study was approved by the ethics committee of the Faculty of Medicine, Heinrich-Heine-University D{\"u}sseldorf (approval reference 6128R). All participants including proxies providing written and informed consent can withdraw from the study at any time. The study findings will be disseminated through scientific journals and public information. TRIAL REGISTRATION NUMBER: DRKS00012554.},
      author = {Andrich, Silke and Ritschel, M. and Meyer, Gabriele and Hoffmann, Falk and Stephan, A. and Baltes, M. and Blessin, J. and Jobski, Kathrin and Fassmer, Alexander Maximilian and Haastert, Burkhard and Gontscharuk, V. and Arend, W. and Theunissen, L. and Colley, D. and Hinze, R. and Thelen, S. and Fuhrmann, P. and Sorg, C. G. G. and Windolf, J. and Rupprecht, C. J. and Icks, Andrea},
      year = {2019},
      title = {Healthcare provision, functional ability and quality of life after proximal femoral fracture - 'ProFem': Study protocol of a population-based, prospective study based on individually linked survey and statutory health insurance data},
      keywords = {*data linkage;*Delivery of Health Care;*healthcare provision;*patient-reported outcomes;*proximal femoral fracture;*Quality of Life;Activities of Daily Living;Aged;Female;Femoral Fractures/epidemiology/*therapy;Germany/epidemiology;Humans;Insurance, Health/*statistics {\&} numerical data;Male;Middle Aged;Patient Discharge;Patient Reported Outcome Measures;Prospective Studies;Research Design;Surveys and Questionnaires},
      pages = {e028144},
      volume = {9},
      number = {6},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2018-028144},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6597653} }
  • [article] bibtex
    L. Ansmann, U. Albert, R. Auer, W. Baumann, E. M. Bitzer, M. Bögel, N. Ernstmann, J. Gostomzyk, K. Götz, U. Hahn, A. Hammer, A. Hollederer, K. Hower, T. Kostuj, C. Kowalski, S. Nöst, M. Nowak, H. Pfaff, L. Rölker-Denker, H. C. Vollmar, und M. A. Wirtz, "DNVF-Memorandum III -- Methoden für die Versorgungsforschung, Teil 4 -- Konzept und Methoden der organisationsbezogenen Versorgungsforschung: Kurzfassung" Das Gesundheitswesen, vol. 81, iss. 3, pp. 220-224, 2019.
    @article{Ansmann.2019, abstract = {Organizational health services research in Germany is of increasing relevance. Based on the guide on methods for organizational health services research of the Memorandum III, part 1 from the year 2009, the fundamentals and standards have now been refined. The memorandum captures the theoretical framework, basic methodological approaches and methods in health services research for the design, evaluation and implementation of complex interventions in healthcare organizations. Das Forschungsfeld der organisationsbezogenen Versorgungforschung ist von zunehmender Bedeutung. Ausgehend von der Vertiefung zu Methoden der organisationsbezogenen Versorgungsforschung des Memorandums III, Teil 1 aus dem Jahr 2009 werden die weiterentwickelten Standards und Grundlagen zusammengefasst. Das Memorandum behandelt die theoretische Rahmung, grundlegende Methodenans{\"a}tze und Methoden zur Konzeption, Evaluation und Implementierung komplexer Interventionen in Versorgungsorganisationen.},
      author = {Ansmann, Lena and Albert, Ute-Susann and Auer, Ramona and Baumann, Walter and Bitzer, Eva Maria and B{\"o}gel, Martina and Ernstmann, Nicole and Gostomzyk, Johannes and G{\"o}tz, Katja and Hahn, Ursula and Hammer, Antje and Hollederer, Alfons and Hower, Kira and Kostuj, Tanja and Kowalski, Christoph and N{\"o}st, Stefan and Nowak, Marina and Pfaff, Holger and R{\"o}lker-Denker, Lars and Vollmar, Horst Christian and Wirtz, Markus Antonius},
      year = {2019},
      title = {DNVF-Memorandum III -- Methoden f{\"u}r die Versorgungsforschung, Teil 4 -- Konzept und Methoden der organisationsbezogenen Versorgungsforschung: Kurzfassung},
      pages = {220--224},
      volume = {81},
      number = {3},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      doi = {10.1055/a-0862-0407},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30952171} }
  • [article] bibtex
    L. Ansmann, W. Baumann, J. Gostomzyk, K. Götz, U. Hahn, H. Pfaff, L. Rölker-Denker, und S. Nöst, "DNVF-Memorandum III -- Methoden für die Versorgungsforschung, Teil 4 -- Konzept und Methoden der organisationsbezogenen Versorgungsforschung. Kapitel 1 -- Definition und Konzept der organisationsbezogenen Versorgungsforschung" Das Gesundheitswesen, vol. 81, iss. 3, p. e64-e71, 2019.
    @article{Ansmann.2019c, abstract = {Organizational health services research is still a relatively young field of research in Germany which is of increasing interest. The German Network Health Services Research e.V. (DNVF e.V.) published in 2009 - supported by expert associations and individual members of the DNVF - a guide on {\textquotedbl}Methods for organizational health services research{\textquotedbl} of the Memorandum III, part 1[1]. Originating from this publication and facilitated by the increasing relevance of the field, a necessity to refine the conceptual and methodological basis became evident. The update and extension of the publication from 2009 consists of three chapters: (1) Definition and concept of organizational health services research, (2) Methodological approaches in organizational health services research: indicators, data sources, data collection and data analysis, (3) Methodological approaches for the design, evaluation and implementation of complex interventions in health care organizations. The aim of the first chapter is to present the theoretical framing and the definition of terms and tasks within organizational health services research. Das Forschungsfeld der organisationsbezogenen Versorgungsforschung ist in Deutschland noch relativ jung und von zunehmendem Interesse. Das Deutsche Netzwerk Versorgungsforschung e.V. (DNVF e.V.) hat im Jahr 2009 -- getragen von den im DNVF organisierten Fachgesellschaften und Mitgliedern -- eine Vertiefung zu {\glqq}Methoden der organisationsbezogenen Versorgungsforschung{\grqq} des Memorandums III, Teil 1 konsentiert [1]. Ausgehend von dieser Ver{\"o}ffentlichung und dem gegenw{\"a}rtigen Bedeutungsgewinn des Forschungsfeldes wurde eine Weiterentwicklung der konzeptionellen und methodischen Grundlagen erforderlich. Die Neuauflage und Erweiterung der Ver{\"o}ffentlichung aus dem Jahr 2009 gliedert sich in drei Kapitel: (1) Definition und Konzept der organisationsbezogenen Versorgungsforschung, (2) Methodische Ans{\"a}tze der organisationsbezogenen Versorgungsforschung: Zielgr{\"o}{\ss}en, Datenquellen, Datenerhebung und Datenanalyse, (3) Methodische Ans{\"a}tze zur Konzeption, Evaluation und Implementierung komplexer Interventionen in Versorgungsorganisationen. Die Herausarbeitung der theoretischen Rahmung und die Definition der Begriffe und Aufgaben der organisationsbezogenen Versorgungsforschung sind Ziele dieses ersten Kapitels.},
      author = {Ansmann, Lena and Baumann, Walter and Gostomzyk, Johannes and G{\"o}tz, Katja and Hahn, Ursula and Pfaff, Holger and R{\"o}lker-Denker, Lars and N{\"o}st, Stefan},
      year = {2019},
      title = {DNVF-Memorandum III -- Methoden f{\"u}r die Versorgungsforschung, Teil 4 -- Konzept und Methoden der organisationsbezogenen Versorgungsforschung. Kapitel 1 -- Definition und Konzept der organisationsbezogenen Versorgungsforschung},
      pages = {e64-e71},
      volume = {81},
      number = {3},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      doi = {10.1055/a-0862-0527},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30952172} }
  • [article] bibtex
    C. A. F. von Arnim, T. Bartsch, A. H. Jacobs, J. Holbrook, P. Bergmann, T. Zieschang, C. M. Polidori, und R. Dodel, "Diagnose und Behandlung kognitiver Störungen" Z Gerontol Geriatr, vol. 52, iss. 4, pp. 309-315, 2019.
    @article{Arnim.2019, abstract = {As a~result of the aging population dementia is a~growing challenge, especially in healthcare. Nevertheless, cognitive disorders are often not systematically evaluated, especially during hospital stays for other reasons; however, cognitive impairment is associated with a~number of geriatric syndromes, including falls, delirium, dysphagia and lack of adherence to treatment plans. This article considers the current state of diagnosis and treatment of dementia. Non-pharmacological therapeutic approaches as well as current and future pharmacological treatment options are discussed. The drugs of choice for the symptomatic treatment of cognitive deficits in Alzheimer's disease and Parkinson-associated dementia are cholinesterase inhibitors and memantine; there is no specific pharmacological treatment for other types of dementia. Prevention and treatment of cardiovascular risk factors can potentially retard the progression of possibly all forms of dementia.},
      author = {von Arnim, Christine A. F. and Bartsch, Thorsten and Jacobs, Andreas H. and Holbrook, Jill and Bergmann, Philipp and Zieschang, Tania and Polidori, M. Cristina and Dodel, Richard},
      year = {2019},
      title = {Diagnose und Behandlung kognitiver St{\"o}rungen},
      pages = {309--315},
      volume = {52},
      number = {4},
      issn = {1435-1269 (Electronic) 0948-6704 (Linking)},
      journal = {Z Gerontol Geriatr},
      doi = {10.1007/s00391-019-01560-0},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31161337} }
  • [article] bibtex
    C. Bachmann, J. Höfer, I. Kamp-Becker, C. Küpper, L. Poustka, S. Roepke, V. Roessner, S. Stroth, N. Wolff, und F. Hoffmann, "Internalised stigma in adults with autism: A German multi-center survey" Psychiatry Res, vol. 276, pp. 94-99, 2019.
    @article{Bachmann.2019b, abstract = {The aim of this study was to evaluate the extent of internalised stigma and possible predictors in adults with a diagnosis of autism spectrum disorder (ASD). We measured internalised stigma in a sample of 149 adults with ASD and an IQ {\textgreater}/=70 (79.2{\%} male, mean age 31.8 years), using the Brief Version of the Internalized Stigma of Mental Illness Scale (ISMI-10). The mean ISMI-10 score was 1.93 (SD=0.57), with 15.4{\%} of participants reporting moderate or severe internalised stigma. Moderate or severe stigma was more frequent in persons aged {\textgreater}/=35 years (OR: 4.36), and in individuals with low educational level (OR: 6.00). IQ, sex and ASD diagnostic subtype (ICD-10) did not influence stigma severity. Compared to other mental disorders, the level of internalised stigma in adults with ASD without intellectual disability appears to be lower.},
      author = {Bachmann, C. and H{\"o}fer, J. and Kamp-Becker, I. and K{\"u}pper, C. and Poustka, L. and Roepke, S. and Roessner, V. and Stroth, S. and Wolff, N. and Hoffmann, Falk},
      year = {2019},
      title = {Internalised stigma in adults with autism: A German multi-center survey},
      keywords = {*Adults;*Autism spectrum disorder;*Defense Mechanisms;*Germany;*ISMI questionnaire;*Social Stigma;*Stigma;Adolescent;Adult;Aged;Autism Spectrum Disorder/diagnosis/*epidemiology/*psychology;Female;Germany/epidemiology;Humans;Intellectual Disability/diagnosis/epidemiology/psychology;Male;Middle Aged;Outpatient Clinics, Hospital/trends;Reproducibility of Results;Surveys and Questionnaires;Young Adult},
      pages = {94--99},
      volume = {276},
      issn = {1872-7123 (Electronic) 0165-1781 (Linking)},
      journal = {Psychiatry Res},
      doi = {10.1016/j.psychres.2019.04.023},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31030006} }
  • [article] bibtex
    C. Bantel, F. Hoffmann, und K. Jobski, "Pain And The Use Of Gabapentinoids In German Nursing Home Residents - Results From An Analysis Based On Statutory Health Insurance Data" J Pain Res, vol. 12, pp. 3175-3184, 2019.
    @article{Bantel.2019, abstract = {BACKGROUND: Gabapentinoids (gabapentin and pregabalin) are psychoactive medications that are increasingly used for different conditions. Since there is evidence that psychotropic drugs, in general, are often inappropriately prescribed in elderly patients, we aimed to determine frequency and indications of gabapentinoid prescribing for nursing home residents. METHODS: We analyzed data from a large German statutory health insurance database. Included were records from people $\geq$65 years-of-age, who were admitted to a nursing home between January 2010 and December 2014. We determined the number and proportion of common indications for on- and off-label prescriptions, the most frequent co-medications, and the characteristics of patients and prescribers. RESULTS: Of 127,277 residents, 9539 (7.5{\%}) received gabapentinoids and 4852 initiated treatment (4.0{\%}; with 66.3{\%} pregabalin). Median age of gabapentinoid initiators was 84 years (78.5{\%} females). In these users, on-label prescribing was found in 57.4{\%},
      predominantly for neuropathic pain. Other painful conditions were also chief causes (84.7{\%}) for off-label prescribing. Gabapentinoids were mainly started by general practitioners (64.5{\%}) while pain specialists contributed {\textless}2{\%}. Forty-six percent of users received additional opioids and in 27.5{\%} gabapentinoids were prescribed only once. CONCLUSION: Gabapentinoids were frequently used in nursing home residents. Regular co-prescribing with opioids and psychotropic drugs might indicate employment to improve pain or assist treatment of conditions that are frequently associated with disruptive behavior such as dementia. However, more research is needed to better understand decision-making regarding gabapentinoid prescribing, especially in view of aggressive marketing, uncertain analgesic effects, problematic side effects, and uncritical use in the elderly.},
      author = {Bantel, Carsten and Hoffmann, Falk and Jobski, Kathrin},
      year = {2019},
      title = {Pain And The Use Of Gabapentinoids In German Nursing Home Residents - Results From An Analysis Based On Statutory Health Insurance Data},
      keywords = {elderly;gabapentinoids;nursing home;pain management;prescribing},
      pages = {3175--3184},
      volume = {12},
      issn = {1178-7090 (Print) 1178-7090},
      journal = {J Pain Res},
      doi = {10.2147/jpr.S221579},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878919} }
  • [article] bibtex
    J. Czwikla, I. Urbschat, J. Kieschke, F. Schussler, I. Langner, und F. Hoffmann, "Assessing and Explaining Geographic Variations in Mammography Screening Participation and Breast Cancer Incidence" Front Oncol, vol. 9, p. 909, 2019.
    @article{Czwikla.2019, abstract = {Investigating geographic variations in mammography screening participation and breast cancer incidence help improve prevention strategies to reduce the burden of breast cancer. This study examined the suitability of health insurance claims data for assessing and explaining geographic variations in mammography screening participation and breast cancer incidence at the district level. Based on screening unit data (1,181,212 mammography screening events), cancer registry data (13,241 incident breast cancer cases) and claims data (147,325 mammography screening events; 1,778 incident breast cancer cases), screening unit and claims-based standardized participation ratios (SPR) of mammography screening as well as cancer registry and claims-based standardized incidence ratios (SIR) of breast cancer between 2011 and 2014 were estimated for the 46 districts of the German federal state of Lower Saxony. Bland-Altman analyses were performed to benchmark claims-based SPR and SIR against screening unit and cancer registry data. Determinants of district-level variations were investigated at the individual and contextual level using claims-based multilevel logistic regression analysis. In claims and benchmark data, SPR showed considerable variations and SIR hardly any. Claims-based estimates were between 0.13 below and 0.14 above (SPR), and between 0.36 below and 0.36 above (SIR) the benchmark. Given the limited suitability of health insurance claims data for assessing geographic variations in breast cancer incidence, only mammography screening participation was investigated in the multilevel analysis. At the individual level, 10 of 31 Elixhauser comorbidities were negatively and 11 positively associated with mammography screening participation. Age and comorbidities did not contribute to the explanation of geographic variations. At the contextual level, unemployment rate was negatively and the proportion of employees with an academic degree positively associated with mammography screening participation. Unemployment, income, education, foreign population and type of district explained 58.5{\%} of geographic variations. Future studies should combine health insurance claims data with individual data on socioeconomic characteristics, lifestyle factors, psychological factors, quality of life and health literacy as well as contextual data on socioeconomic characteristics and accessibility of mammography screening. This would allow a comprehensive investigation of geographic variations in mammography screening participation and help to further improve prevention strategies for reducing the burden of breast cancer.},
      author = {Czwikla, Jonas and Urbschat, I. and Kieschke, Joachim and Schussler, F. and Langner, I. and Hoffmann, Falk},
      year = {2019},
      title = {Assessing and Explaining Geographic Variations in Mammography Screening Participation and Breast Cancer Incidence},
      keywords = {breast cancer;cancer registry data;geographic variations;health insurance claims data;incidence;mammography screening;participation;screening unit data},
      pages = {909},
      volume = {9},
      issn = {2234-943X (Print) 2234-943X (Linking)},
      journal = {Front Oncol},
      doi = {10.3389/fonc.2019.00909},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759661},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31620366} }
  • [article] bibtex
    M. Dörks, K. Allers, und F. Hoffmann, "Pro Re Nata Drug Use in Nursing Home Residents: A Systematic Review" J Am Med Dir Assoc, vol. 20, iss. 3, pp. 287-293, 2019.
    @article{Dorks.2019, abstract = {OBJECTIVES: In addition to routinely administered long-term medication, complex drug regimens of nursing home residents often include as needed or pro re nata (PRN) medication. However, there has been no systematic evaluation of the frequency and concomitants of PRN medication in nursing homes. The main objective of this systematic review was to provide a current assessment of PRN drug use in nursing homes. DESIGN: A systematic literature search was performed. Data were identified from 4 electronic bibliographic databases: MEDLINE, Embase, CINAHL, and Scopus. Studies were included if they reported quantitative data on PRN drug use in nursing home residents. RESULTS: Our search strategy resulted in 484 hits, of which 27 articles satisfied the inclusion criteria. The mean number of PRN drugs ranged between 0.4 and 4.9 per resident with a median of 2.5. The proportion of residents prescribed at least 1 PRN drug was between 48.4{\%} and 97.4{\%} (median~=~74.9). Administration of prescribed PRN medication was rather low as the proportion of residents with administered PRN drugs ranged from 28{\%} to 55{\%}. Frequently prescribed PRN drugs were analgesics, laxatives, and sedatives. Advanced age, dementia, a higher number of regularly scheduled medications, and length of stay in the nursing home were associated with higher use of PRN drugs. CONCLUSIONS/IMPLICATIONS: Although not regularly administered, PRN drug use in nursing home residents should be taken into account as part of complex drug regimens. In that sense, there seems to be an inadequate number of studies reporting on it. When screening tools like the Beers Criteria are adapted, PRN drugs should be included.},
      author = {D{\"o}rks, Michael and Allers, Katharina and Hoffmann, Falk},
      year = {2019},
      title = {Pro Re Nata Drug Use in Nursing Home Residents: A Systematic Review},
      keywords = {*as-needed drugs;*Drug Utilization;*nursing home residents;*Nursing Homes;*potential inappropriate medication;*Potentially Inappropriate Medication List;*Pro re nata drug use;Aged;Aged, 80 and over;Cross-Sectional Studies;Drug Prescriptions;Female;Humans;Male;polypharmacy},
      pages = {287--293},
      volume = {20},
      number = {3},
      issn = {1525-8610},
      journal = {J Am Med Dir Assoc},
      doi = {10.1016/j.jamda.2018.10.024} }
  • [article] bibtex
    J. Höfer, F. Hoffmann, I. Kamp-Becker, L. Poustka, V. Roessner, S. Stroth, N. Wolff, und C. Bachmann, "Pathways to a diagnosis of autism spectrum disorder in Germany: a survey of parents" Child Adolesc Psychiatry Ment Health, vol. 13, p. 16, 2019.
    @article{Hofer.2019, abstract = {Background: Early identification of autism spectrum disorders (ASD) is a prerequisite for access to early interventions. Although parents often note developmental atypicalities during the first 2 years of life, many children with ASD are not diagnosed until school age. For parents, the long period between first parental concerns and diagnosis is often frustrating and accompanied by uncertainty and worry. Methods: This study retrospectively explored the trajectories of children with a confirmed ASD diagnosis during the diagnostic process, from first parental concerns about their child's development until the definite diagnosis. A survey concerning the diagnostic process was distributed to parents or legal guardians of children with ASD from three specialized ASD outpatient clinics in Germany. Results: The response rate was 36.9{\%},
      and the final sample consisted of carers of 207 affected children (83.6{\%} male, mean age 12.9 years). The children had been diagnosed with childhood autism (55.6{\%}), Asperger syndrome (24.2{\%}), or atypical autism (20.3{\%}). On average, parents had first concerns when their child was 23.4 months old, and an ASD diagnosis was established at a mean age of 78.5 months. Children with atypical autism or Asperger syndrome were diagnosed significantly later (83.9 and 98.1 months, respectively) than children with childhood autism (68.1 months). Children with an IQ {\textless} 85 were diagnosed much earlier than those with an IQ {\textgreater}/= 85. On average, parents visited 3.4 different health professionals (SD = 2.4, range 1-20, median: 3.0) until their child received a definite ASD diagnosis. Overall, 38.5{\%} of carers were satisfied with the diagnostic process. Conclusions: In this sample of children with ASD in Germany, the time to diagnosis was higher than in the majority of other comparable studies. These results flag the need for improved forms of service provision and delivery for suspected cases of ASD in Germany.},
      author = {H{\"o}fer, J. and Hoffmann, Falk and Kamp-Becker, I. and Poustka, L. and Roessner, V. and Stroth, S. and Wolff, N. and Bachmann, C.},
      year = {2019},
      title = {Pathways to a diagnosis of autism spectrum disorder in Germany: a survey of parents},
      keywords = {Autism;Autism spectrum disorder;Diagnosis;Diagnostic process;Germany;Pathways;Satisfaction},
      pages = {16},
      volume = {13},
      issn = {1753-2000 (Print) 1753-2000},
      journal = {Child Adolesc Psychiatry Ment Health},
      doi = {10.1186/s13034-019-0276-1},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30949235},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429704} }
  • [article] bibtex
    J. Höfer, C. Bachmann, I. Kamp-Becker, L. Poustka, V. Roessner, S. Stroth, N. Wolff, und F. Hoffmann, "Willingness to try and lifetime use of complementary and alternative medicine in children and adolescents with autism spectrum disorder in Germany: A survey of parents" Autism, vol. 23, iss. 7, pp. 1865-1870, 2019.
    @article{Hofer.2019c, abstract = {Regardless of their limited evidence and potential adverse effects, use of complementary and alternative medicine is common in children with autism spectrum disorder. Nevertheless, data on complementary and alternative medicine use in children with autism spectrum disorder in Germany are lacking. Therefore, a questionnaire survey on the use of complementary and alternative medicine was distributed to parents of children with autism spectrum disorder from three academic autism spectrum disorder outpatient clinics in Germany. Of 211 respondents, 46{\%} stated that their child currently used or had ever used some form of complementary and alternative medicine in their life. The complementary and alternative medicine modalities most frequently used were manipulative and body-based methods (e.g. craniosacral therapy). And 18{\%} of caregivers expressed willingness to try complementary and alternative medicine treatments for their child with autism spectrum disorder in the future, with mind-body interventions predominating. Health professionals should be aware of the considerable complementary and alternative medicine use prevalence among children with autism spectrum disorder and offer parents information about its effectiveness and potential side effects.},
      author = {H{\"o}fer, J. and Bachmann, C. and Kamp-Becker, I. and Poustka, L. and Roessner, V. and Stroth, S. and Wolff, N. and Hoffmann, Falk},
      year = {2019},
      title = {Willingness to try and lifetime use of complementary and alternative medicine in children and adolescents with autism spectrum disorder in Germany: A survey of parents},
      keywords = {*Autism spectrum disorder;*complementary and alternative medicine;*Germany;*prevalence;Adolescent;Autism Spectrum Disorder/psychology/*therapy;Child;Child, Preschool;Complementary Therapies/*statistics {\&} numerical data;Female;Germany;Humans;Infant;Male;Parents/*psychology;Patient Acceptance of Health Care/statistics {\&} numerical data;Surveys and Questionnaires},
      pages = {1865--1870},
      volume = {23},
      number = {7},
      issn = {1362-3613},
      journal = {Autism},
      doi = {10.1177/1362361318823545} }
  • [article] bibtex
    K. Jobski, C. Bantel, und F. Hoffmann, "Utilization of transdermal fentanyl in German nursing home residents from 2010 to 2014" Pharmacoepidemiol Drug Saf, vol. 28, iss. 5, pp. 754-759, 2019.
    @article{Jobski.2019,
      author = {Jobski, Kathrin and Bantel, Carsten and Hoffmann, Falk},
      year = {2019},
      title = {Utilization of transdermal fentanyl in German nursing home residents from 2010 to 2014},
      keywords = {*aged;*Analgesics, Opioid/administration {\&} dosage/therapeutic use;*fentanyl;*Fentanyl/administration {\&} dosage/therapeutic use;*nursing home;*pharmacoepidemiology;Administration, Cutaneous;Aged;Aged, 80 and over;Cohort Studies;Drug Utilization/*statistics {\&} numerical data;Female;Germany;Humans;Male;Nursing Homes/*statistics {\&} numerical data},
      pages = {754--759},
      volume = {28},
      number = {5},
      issn = {1053-8569},
      journal = {Pharmacoepidemiol Drug Saf},
      doi = {10.1002/pds.4753},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30861622} }
  • [article] bibtex
    J. Koschate, U. Drescher, A. Werner, L. Thieschäfer, und U. Hoffmann, "Cardiovascular regulation: associations between exercise and head-up tilt" Canadian journal of physiology and pharmacology, vol. 97, iss. 8, pp. 738-745, 2019.
    @article{Koschate.2019d, abstract = {It was hypothesized that faster cardiorespiratory kinetics during exercise are associated with higher orthostatic tolerance. Cardiorespiratory kinetics of 14 healthy male subjects (30 $\pm$ 4 years, 179 $\pm$ 8 cm, 79 $\pm$ 8 kg) were tested on a cycle ergometer during exercise with changing work rates of 30 and 80 W. Pulmonary oxygen uptake ( ) was measured breath-by-breath and heart rate (HR), mean arterial blood pressure (MAP), and total peripheral resistance (TPR) were measured beat-to-beat. Muscular oxygen uptake ( ) was estimated from HR and . Kinetic parameters were determined by time-series analysis, using cross-correlation functions (CCFmax(x)) between the parameter and the work rate. Cardiovascular regulations of MAP, HR, and TPR during orthostatic stress were measured beat-to-beat on a tilt seat. Changes between the minima and maxima during the 6° head-down tilt and the 90° head-up tilt positions were calculated for each parameter (\textgreek{D}tilt-up). correlated significantly with \textgreek{D}TPRtilt-up (r = 0.790, p $\leq$ 0.001). CCFmax(HR) was significantly correlated with \textgreek{D}HRtilt-up (r = -0.705, p = 0.002) and the amplitude in HR from 30 to 80 W (rSP = -0.574, p = 0.016). The observed correlations between cardiorespiratory regulation in response to exercise and orthostatic stress during rest might allow for a more differential analysis of the underlying mechanisms of orthostatic intolerance in, for example, patient groups.},
      author = {Koschate, J. and Drescher, U. and Werner, A. and Thiesch{\"a}fer, L. and Hoffmann, U.},
      year = {2019},
      title = {Cardiovascular regulation: associations between exercise and head-up tilt},
      pages = {738--745},
      volume = {97},
      number = {8},
      journal = {Canadian journal of physiology and pharmacology},
      doi = {10.1139/cjpp-2018-0742},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30917299} }
  • [article] bibtex
    C. Lins, D. Eckhoff, A. Klausen, S. Hellmers, A. Hein, und S. Fudickar, "Cardiopulmonary resuscitation quality parameters from motion capture data using Differential Evolution fitting of sinusoids" Applied Soft Computing Journal, vol. 79, pp. 300-309, 2019.
    @article{Lins.2019, abstract = {Cardiopulmonary resuscitation (CPR) is alongside electrical defibrillation the most crucial countermeasure for sudden cardiac arrest, which affects thousands of individuals every year. In this paper, we present a novel approach including sinusoid models that use skeletal motion data from an RGB-D (Kinect) sensor and the Differential Evolution (DE) optimization algorithm to dynamically fit sinusoidal curves to derive frequency and depth parameters for cardiopulmonary resuscitation training. It is intended to be part of a robust and easy-to-use feedback system for CPR training, allowing its use for unsupervised training. The accuracy of this DE-based approach is evaluated in comparison with data of 28 participants recorded by a state-of-the-art training mannequin. We optimized the DE algorithm hyperparameters and showed that with these optimized parameters the frequency of the CPR is recognized with a median error of $\pm$2.9 compressions per minute compared to the reference training mannequin.},
      author = {Lins, Christian and Eckhoff, Daniel and Klausen, Andreas and Hellmers, Sandra and Hein, Andreas and Fudickar, Sebastian},
      year = {2019},
      title = {Cardiopulmonary resuscitation quality parameters from motion capture data using Differential Evolution fitting of sinusoids},
      keywords = {Cardiac arrest;CPR Training;Differential Evolution;Kinect;Motion Capture;Resuscitation;Sinusoid regression model},
      pages = {300--309},
      volume = {79},
      issn = {15684946},
      journal = {Applied Soft Computing Journal},
      doi = {10.1016/j.asoc.2019.03.023},
      file = {Lins et al. - 2019 - Cardiopulmonary resuscitation quality parameters from motion capture data using Differential Evolution fitting of s:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins et al. - 2019 - Cardiopulmonary resuscitation quality parameters from motion capture data using Differential Evolution fitting of s.pdf:pdf} }
  • [article] bibtex
    A. Luque Ramos, I. Redeker, F. Hoffmann, J. Callhoff, A. Zink, und K. Albrecht, "Comorbidities in Patients with Rheumatoid Arthritis and Their Association with Patient-reported Outcomes: Results of Claims Data Linked to Questionnaire Survey" J Rheumatol, vol. 46, iss. 6, pp. 564-571, 2019.
    @article{LuqueRamos.2019, abstract = {OBJECTIVE: To investigate the prevalence of comorbidities in a population-based cohort of persons with rheumatoid arthritis (RA) compared to matched controls and to examine their association with patient-reported outcomes in a survey sample. METHODS: Data of 96,921 persons with RA [International Classification of Diseases, 10th ed (ICD-10) M05/M06] and 484,605 age- and sex-matched controls without RA of a German statutory health fund were studied regarding 26 selected comorbidities (ICD-10). A self-reported questionnaire, comprising joint counts [(tender joint count (TJC), swollen joint count (SJC)], functional status (Hannover Functional Ability Questionnaire), effect of the disease (Rheumatoid Arthritis Impact of Disease), and well-being (World Health Organization 5-item Well-Being Index; WHO-5) was sent to a random sample of 6193 persons with RA, of whom 3184 responded. For respondents who confirmed their RA (n = 2535), associations between comorbidities and patient-reported outcomes were analyzed by multivariable linear regression. RESULTS: Compared to controls, all investigated comorbidities were more frequent in persons with RA (mean age 63 yrs, 80{\%} female). In addition to cardiovascular risk factors, the most common were osteoarthritis (44{\%} vs 21{\%}), depression (32{\%} vs 20{\%}), and osteoporosis (26{\%} vs 9{\%}). Among the survey respondents, 87{\%} of those with 0-1 comorbidity but only 77{\%} of those with $\geq$ 8 comorbidities were treated by rheumatologists. Increasing numbers of comorbidities were associated with poorer values for TJC, SJC, function, and WHO-5. CONCLUSION: Compared to a matched population, persons with RA present with increased prevalence of numerous comorbidities. Patients with RA and multimorbidity are at risk of insufficient rheumatological care and poorer patient-reported outcomes.},
      author = {{Luque Ramos},
      A. and Redeker, Imke and Hoffmann, Falk and Callhoff, Johanna and Zink, Angela and Albrecht, Katinka},
      year = {2019},
      title = {Comorbidities in Patients with Rheumatoid Arthritis and Their Association with Patient-reported Outcomes: Results of Claims Data Linked to Questionnaire Survey},
      keywords = {*comorbidity;*depression;*epidemiology;*healthcare;*rheumatoid arthritis;Aged;Arthritis, Rheumatoid/diagnosis/*epidemiology;Comorbidity;Depressive Disorder/*epidemiology;Female;Humans;Male;Middle Aged;Osteoarthritis/*epidemiology;Patient Reported Outcome Measures;Prevalence;Severity of Illness Index;Surveys and Questionnaires},
      pages = {564--571},
      volume = {46},
      number = {6},
      issn = {0315-162X (Print) 0315-162x},
      journal = {J Rheumatol},
      doi = {10.3899/jrheum.180668} }
  • [article] bibtex
    L. Rölker-Denker, C. Kowalski, L. Ansmann, U. Hahn, A. Hammer, R. Auer, T. Kostuj, und S. Nöst, "DNVF-Memorandum III -- Methoden für die Versorgungsforschung, Teil 4 -- Konzept und Methoden der organisationsbezogenen Versorgungsforschung. Kapitel 2 -- Methodische Ansätze der organisationsbezogenen Versorgungsforschung: Zielgrößen, Datenquellen, Datenerhebung und Datenanalyse" Das Gesundheitswesen, vol. 81, iss. 3, p. e72-e81, 2019.
    @article{RolkerDenker.2019, abstract = {Organizational health services research is still a relatively young field of research in Germany which is of increasing interest. The German Network Health Services Research e.V. (DNVF e.V.) published in 2009 - supported by expert associations and individual members of the DNVF - a guide on {\textquotedbl}Methods for organizational health services research{\textquotedbl} of the Memorandum III, part 1 1. Originating from this publication and facilitated by the increasing relevance of the field, a necessity to refine the conceptual and methodological basis became evident. The update and extension of the publication from 2009 consists of 3 chapters: (1) Definition and concept of organizational health services research, (2) Methodological approaches in organizational health services research: indicators, data sources, data collection and data analysis, (3) Methodological approaches for the design, evaluation and implementation of complex interventions in healthcare organizations. The aim of the second chapter is to derive methodological requirements and characteristics of organizational health services research - based on the unique characteristics of the research field presented in chapter 1. Das Forschungsfeld der organisationsbezogenen Versorgungsforschung ist in Deutschland noch relativ jung und von zunehmendem Interesse. Das Deutsche Netzwerk Versorgungsforschung e.V. (DNVF e.V.) hat im Jahr 2009 -- getragen von den im DNVF organisierten Fachgesellschaften und Mitgliedern -- eine Vertiefung zu {\glqq}Methoden der organisationsbezogenen Versorgungsforschung{\grqq} des Memorandums III, Teil 1 konsentiert 1. Ausgehend von dieser Ver{\"o}ffentlichung und dem gegenw{\"a}rtigen Bedeutungsgewinn des Forschungsfeldes ist eine Weiterentwicklung der konzeptionellen und methodischen Grundlage erforderlich. Die Neuauflage und Erweiterung der Ver{\"o}ffentlichung aus dem Jahr 2009 gliedert sich in 3 Kapitel: (1) Definition und Konzept der organisationsbezogenen Versorgungsforschung, (2) Methodische Ans{\"a}tze der Organisationsbezogenen Versorgungsforschung: Zielgr{\"o}{\ss}en, Datenquellen, Datenerhebung und Datenanalyse, (3) Methodische Ans{\"a}tze zur Konzeption, Evaluation und Implementierung komplexer Interventionen in Versorgungsorganisationen. Die Herausarbeitung der methodischen Besonderheiten der organisationsbezogenen Versorgungsforschung -- aufbauend auf den in Kapitel 1 dargestellten Besonderheiten des Forschungsgegenstandes -- ist Ziel dieses zweiten Kapitels.},
      author = {R{\"o}lker-Denker, Lars and Kowalski, Christoph and Ansmann, Lena and Hahn, Ursula and Hammer, Antje and Auer, Ramona and Kostuj, Tanja and N{\"o}st, Stefan},
      year = {2019},
      title = {DNVF-Memorandum III -- Methoden f{\"u}r die Versorgungsforschung, Teil 4 -- Konzept und Methoden der organisationsbezogenen Versorgungsforschung. Kapitel 2 -- Methodische Ans{\"a}tze der organisationsbezogenen Versorgungsforschung: Zielgr{\"o}{\ss}en, Datenquellen, Datenerhebung und Datenanalyse},
      pages = {e72-e81},
      volume = {81},
      number = {3},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      doi = {10.1055/a-0862-0565},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30952173} }
  • [article] bibtex
    M. A. Wirtz, E. M. Bitzer, U. Albert, L. Ansmann, M. Bögel, N. Ernstmann, A. Hollederer, K. Hower, M. Nowak, und H. C. Vollmar, "DNVF-Memorandum III -- Methoden für die Versorgungsforschung, Teil 4 -- Konzept und Methoden der organisationsbezogenen Versorgungsforschung. Kapitel 3 -- Methodische Ansätze zur Evaluation und Implementierung komplexer Interventionen in Versorgungsorganisationen" Das Gesundheitswesen, vol. 81, iss. 3, p. e82-e91, 2019.
    @article{Wirtz.2019, abstract = {Organizational health services research is still a relatively young field of research in Germany which is of increasing interest. The German Network Health Services Research e.V. (DNVF e.V.) published in 2009 - supported by expert associations and individual members of the DNVF - a guide on {\textquotedbl}Methods for organizational health services research{\textquotedbl} of the Memorandum III, part 1 [1]. Originating from this publication and facilitated by the increasing relevance of the field, a necessity to refine the conceptual and methodological basis became evident. The update and extension of the publication from 2009 consists of three chapters: (1) Definition and concept of organizational health services research, (2) Methodological approaches in organizational health services research: indicators, data sources, data collection and data analysis, (3) Methodological approaches for the design, evaluation and implementation of complex interventions in health care organizations. The aim of the third chapter is to present methods for intervention design, evaluation of effectiveness and efficacy as well as implementation research with particular regard to the organizational context of interventions to improve health care. Das Forschungsfeld der organisationsbezogenen Versorgungsforschung ist in Deutschland noch relativ jung und von zunehmendem Interesse. Das Deutsche Netzwerk Versorgungsforschung e. V. (DNVF e. V.) hat im Jahr 2009 -- getragen von den im DNVF organisierten Fachgesellschaften und Mitgliedern -- eine Vertiefung zu {\glqq}Methoden der organisationsbezogenen Versorgungsforschung{\grqq} des Memorandums III, Teil 1 konsentiert [1]. Ausgehend von dieser Ver{\"o}ffentlichung und dem gegenw{\"a}rtigen Bedeutungsgewinn des Forschungsfeldes ist eine Weiterentwicklung der konzeptionellen und methodischen Grundlage erforderlich. Die Neuauflage und Erweiterung der Ver{\"o}ffentlichung aus dem Jahr 2009 gliedert sich in 3 Kapitel: (1) Definition und Konzept der organisationsbezogenen Versorgungsforschung, (2) Methodische Ans{\"a}tze der organisationsbezogenen Versorgungsforschung: Zielgr{\"o}{\ss}en, Datenquellen, Datenerhebung, und Datenanalyse, (3) Methodische Ans{\"a}tze zur Konzeption, Evaluation und Implementierung komplexer Interventionen in Versorgungsorganisationen. Ziel des dritten Kapitels ist es, Methoden f{\"u}r das Design von Interventionen, f{\"u}r die Wirkungs- und Wirksamkeitsforschung sowie f{\"u}r die Implementierungsforschung unter besonderer Ber{\"u}cksichtigung des organisationalen Kontextes, in dem Versorgungsinterventionen stattfinden, vorzustellen.},
      author = {Wirtz, Markus Antonius and Bitzer, Eva Maria and Albert, Ute-Susann and Ansmann, Lena and B{\"o}gel, Martina and Ernstmann, Nicole and Hollederer, Alfons and Hower, Kira and Nowak, Marina and Vollmar, Horst Christian},
      year = {2019},
      title = {DNVF-Memorandum III -- Methoden f{\"u}r die Versorgungsforschung, Teil 4 -- Konzept und Methoden der organisationsbezogenen Versorgungsforschung. Kapitel 3 -- Methodische Ans{\"a}tze zur Evaluation und Implementierung komplexer Interventionen in Versorgungsorganisationen},
      pages = {e82-e91},
      volume = {81},
      number = {3},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      doi = {10.1055/a-0862-0588},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30952174} }
  • [article] bibtex
    T. Zieschang, J. Bauer, D. Kopf, und A. Rösler, "Spezialstationen für Patienten mit kognitiver Einschränkung : Ergebnisse einer Umfrage in Kliniken für Geriatrie in Deutschland" Z Gerontol Geriatr, vol. 52, iss. 6, pp. 598-606, 2019.
    @article{Zieschang.2019, abstract = {BACKGROUND A large number of older acutely ill patients with cognitive impairment are treated in geriatric care units. Since 1990 some geriatric departments in Germany have established special care units (SCU) for this patient population. In 2010 the first inventory of SCUs in Germany was carried out, which was not based on a~nationwide systematic survey. OBJECTIVE Nationwide systematic survey of SCUs for patients with cognitive impairment in geriatric institutions in Germany. METHODS An online questionnaire (SurveyMonkey{\circledR},
      San Mateo, CA, USA) was sent to all heads of geriatric departments that provide advanced education in geriatric medicine of at least 12 months as registered by the German Society for Geriatric Medicine (DGG). RESULTS The questionnaire was sent to 495 geriatric institutions of which 161 answered (response rate 32.5{\%}). Additionally, 13~institutions answered through a~weblink sent in a~newsletter by the DGG. In 2017 a total of 42~SCUs existed with a~mean size of 13.5 $\pm$ 4.7~beds. A further 15 hospitals plan to install an SCU in the near future, 5 probably in 2018. In four geriatric departments an existing SCU was closed down. All SCUs implemented special architectural, structural and personnel measures as recommended by the position paper of the DGG. The few conducted evaluations indicated beneficial results for mobility and disruptive behavior. CONCLUSION In recent years the number of SCUs has increased considerably. A~methodologically sound evaluation with respect to patient-related outcomes including follow-up and cost-effectiveness is lacking and should be carried out in the near future.},
      author = {Zieschang, Tania and Bauer, J{\"u}rgen and Kopf, Daniel and R{\"o}sler, Alexander},
      year = {2019},
      title = {Spezialstationen f{\"u}r Patienten mit kognitiver Einschr{\"a}nkung : Ergebnisse einer Umfrage in Kliniken f{\"u}r Geriatrie in Deutschland},
      pages = {598--606},
      volume = {52},
      number = {6},
      issn = {1435-1269 (Electronic) 0948-6704 (Linking)},
      journal = {Z Gerontol Geriatr},
      doi = {10.1007/s00391-018-1439-z},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30178120} }
  • [incollection] bibtex
    M. Schweda, "Empirische Sozialforschung in der Medizinethik. Aufgaben, Methoden, Anwendungsbeispiele" in Philosophie zwischen Sein und Sollen, Bauer, A. M. und Meyerhuber, M. I., Eds., Berlin: De Gruyter, 2019, vol. 2019, pp. 73-92.
    @incollection{Schweda.2019d,
      author = {Schweda, Mark},
      title = {Empirische Sozialforschung in der Medizinethik. Aufgaben, Methoden, Anwendungsbeispiele},
      pages = {73--92},
      volume = {2019},
      publisher = {{De Gruyter}},
      isbn = {978-3-11-061377-3 978-3-11-061215-8},
      editor = {Bauer, Alexander Max and Meyerhuber, Malte Ingo},
      booktitle = {Philosophie zwischen Sein und Sollen},
      year = {2019},
      address = {Berlin},
      doi = {10.1515/9783110613773} }
  • [incollection] bibtex | Dokument aufrufen Dokument aufrufen
    A. Urban und M. Schweda, "Zwischen Revisionismus und Normalisierung. Eine Analyse des bioethischen Diskurses um genomische Hochdurchsatztechnologien" in Next-generation medicine? Ethical, Legal and Technological Questions of Genomic High-Throughput Sequencing in the Clinic, Duttge, G., Sax, U., Schweda, M., und Umbach, N., Eds., Tübingen: Mohr Siebeck, 2019, vol. 2019, pp. 77-97.
    @incollection{Urban.2019,
      author = {Urban, Alexander and Schweda, Mark},
      title = {Zwischen Revisionismus und Normalisierung. Eine Analyse des bioethischen Diskurses um genomische Hochdurchsatztechnologien},
      url = {http://kxp.k10plus.de/DB=2.1/PPNSET?PPN=1677262567},
      pages = {77--97},
      volume = {2019},
      publisher = {{Mohr Siebeck}},
      isbn = {978-3-16-155861-0 3-16-155861-8},
      editor = {Duttge, Gunnar and Sax, Ulrich and Schweda, Mark and Umbach, Nadine},
      booktitle = {Next-generation medicine? Ethical, Legal and Technological Questions of Genomic High-Throughput Sequencing in the Clinic},
      year = {2019},
      address = {T{\"u}bingen} }
  • [article] bibtex
    K. Allers, F. Hoffmann, und R. Schnakenberg, "Hospitalizations of nursing home residents at the end of life: A systematic review" Palliat Med, vol. 33, iss. 10, pp. 1282-1298, 2019.
    @article{Allers.2019, abstract = {BACKGROUND: End-of-life hospitalizations in nursing home residents are common, although they are often burdensome and potentially avoidable. AIM: We aimed to summarize the existing evidence on end-of-life hospitalizations in nursing home residents. DESIGN: Systematic review (PROSPERO registration number CRD42017072276). DATA SOURCES: A systematic literature search was carried out in PubMed, CINAHL, and Scopus (date of search 9 April 2019). Studies were included if they reported proportions of in-hospital deaths or hospitalizations of nursing home residents in the last month of life. Two authors independently selected studies, extracted data, and assessed the quality of studies. Median with interquartile range was used to summarize proportions. RESULTS: A total of 35 studies were identified, more than half of which were from the United States (n = 18). While 29 studies reported in-hospital deaths, 12 studies examined hospitalizations during the last month of life. The proportion of in-hospital deaths varied markedly between 5.9{\%} and 77.1{\%},
      with an overall median of 22.6{\%} (interquartile range: 16.3{\%}-29.5{\%}). The proportion of residents being hospitalized during the last month of life ranged from 25.5{\%} to 69.7{\%},
      and the median was 33.2{\%} (interquartile range: 30.8{\%}-38.4{\%}). Most studies investigating the influence of age found that younger age was associated with a higher likelihood of end-of-life hospitalization. Four studies assessed trends over time, showing heterogeneous findings. CONCLUSION: There is a wide variation in end-of-life hospitalizations, even between studies from the same country. Overall, such hospitalizations are common among nursing home residents, which indicates that interventions tailored to each specific health care system are needed to improve end-of-life care.},
      author = {Allers, Katharina and Hoffmann, Falk and Schnakenberg, Rieke},
      year = {2019},
      title = {Hospitalizations of nursing home residents at the end of life: A systematic review},
      keywords = {*end of life;*Hospitalization;*in-hospital death;*nursing home;*Systematic review;Age Factors;article.;Hospital Mortality;Hospitalization/*statistics {\&} numerical data;Humans;Nursing Homes/*statistics {\&} numerical data;of interest with respect to the research,
      authorship, and/or publication of this;Terminal Care/*statistics {\&} numerical data},
      pages = {1282--1298},
      volume = {33},
      number = {10},
      issn = {0269-2163 (Print) 0269-2163},
      journal = {Palliat Med},
      doi = {10.1177/0269216319866648},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899437} }
  • [article] bibtex
    J. Callhoff, K. Albrecht, F. Hoffmann, D. Poddubnyy, K. Günther, und A. Zink, "[Reality of care for musculoskeletal diseases at the population level : Results of the PROCLAIR collaborative project. German version]" Z Rheumatol, vol. 78, iss. 8, pp. 713-721, 2019.
    @article{Callhoff.2019, abstract = {BACKGROUND: The objective of the research consortium PROCLAIR was to gain population level knowledge on the treatment of patients with rheumatoid arthritis (RA), axial spondylarthritis (axSpA) and osteoarthritis (OA) in Germany. AIMS: A main question of the consortium was whether it is possible to identify groups of people who were exposed to a~particular risk of undersupply or oversupply of treatment. In addition, the study investigated the validity of claims data for these diseases as a~basis for further studies. PATIENTS AND METHODS: Cross-sectional surveys were carried out among insurees of the BARMER statutory health insurance fund whose claims data included RA, axSpA and OA diagnoses. The questionnaire data were linked with the claims data of the insured persons if they agreed. RESULTS: In all three diseases risk groups for care deficits could be identified. Persons with RA who are not treated by a~specialist have less access to drug treatment. Physical therapy is prescribed for all three diagnoses at a~low level, even for people undergoing joint replacement surgery. A connection between depressive symptoms and disease activity or function in axSpA was shown. In addition to the results relevant to care, the PROCLAIR network has also made contributions to critically assess the quality of health insurance data. DISCUSSION: The combination of billing data with survey data enables a~comprehensive description of the treatment of musculoskeletal diseases. Particularly relevant factors are the specialization of the physician, sociodemographic parameters of the patients and the region of residence. In particular, access to treatment cannot be investigated in randomized clinical trials.},
      author = {Callhoff, Johanna and Albrecht, Katinka and Hoffmann, Falk and Poddubnyy, Denis and G{\"u}nther, Klaus--Peter and Zink, Angela},
      year = {2019},
      title = {[Reality of care for musculoskeletal diseases at the population level : Results of the PROCLAIR collaborative project. German version]},
      keywords = {*Arthritis, Rheumatoid/diagnosis/therapy;*Osteoarthritis/diagnosis/therapy;*Spondylarthritis/diagnosis/therapy;Billing data;Biological Products/therapeutic use;Cross-Sectional Studies;Disease burden;Germany;Humans;Inflammatory rheumatic diseases;Physical Therapy Modalities;Surveys and Questionnaires;Treatment;Treatment deficits},
      pages = {713--721},
      volume = {78},
      number = {8},
      issn = {0340-1855},
      journal = {Z Rheumatol},
      originalyear = {Versorgungswirklichkeit muskuloskeletaler Erkrankungen auf Bev{\"o}lkerungsebene : Erkenntnisse aus dem Verbundprojekt PROCLAIR.},
      doi = {10.1007/s00393-019-0664-1} }
  • [article] bibtex
    J. Callhoff, K. Albrecht, F. Hoffmann, D. Poddubnyy, K. Günther, und A. Zink, "Reality of care for musculoskeletal diseases at the population level : Results of the PROCLAIR collaborative project" Z Rheumatol, vol. 78, iss. Suppl 2, pp. 73-79, 2019.
    @article{Callhoff.2019b, abstract = {BACKGROUND: The objective of the research consortium PROCLAIR was to gain population level knowledge on the treatment of patients with rheumatoid arthritis (RA), axial spondylarthritis (axSpA) and osteoarthritis (OA) in Germany. AIMS: A main question of the consortium was whether it is possible to identify groups of people who were exposed to a~particular risk of undersupply or oversupply of treatment. In addition, the study investigated the validity of claims data for these diseases as a~basis for further studies. PATIENTS AND METHODS: Cross-sectional surveys were carried out among insurees of the BARMER statutory health insurance fund whose claims data included RA, axSpA and OA diagnoses. The questionnaire data were linked with the claims data of the insured persons if they agreed. RESULTS: In all three diseases risk groups for care deficits could be identified. Persons with RA who are not treated by a~specialist have less access to drug treatment. Physical therapy is prescribed for all three diagnoses at a~low level, even for people undergoing joint replacement surgery. A connection between depressive symptoms and disease activity or function in axSpA was shown. In addition to the results relevant to care, the PROCLAIR network has also made contributions to critically assess the quality of health insurance data. DISCUSSION: The combination of billing data with survey data enables a~comprehensive description of the treatment of musculoskeletal diseases. Particularly relevant factors are the specialization of the physician, sociodemographic parameters of the patients and the region of residence. In particular, access to treatment cannot be investigated in randomized clinical trials.},
      author = {Callhoff, Johanna and Albrecht, Katinka and Hoffmann, Falk and Poddubnyy, Denis and G{\"u}nther, Klaus--Peter and Zink, Angela},
      year = {2019},
      title = {Reality of care for musculoskeletal diseases at the population level : Results of the PROCLAIR collaborative project},
      keywords = {*Arthritis, Rheumatoid/therapy;*Health Services Accessibility;*Osteoarthritis/therapy;*Spondylarthritis/therapy;Billing data;Cross-Sectional Studies;Disease burden;Germany;Humans;Inflammatory rheumatic diseases;Treatment;Treatment deficits},
      pages = {73--79},
      volume = {78},
      number = {Suppl 2},
      issn = {0340-1855},
      journal = {Z Rheumatol},
      originalyear = {Versorgungswirklichkeit muskuloskeletaler Erkrankungen auf Bev{\"o}lkerungsebene : Erkenntnisse aus dem Verbundprojekt PROCLAIR. Englische Version.},
      doi = {10.1007/s00393-019-0669-9} }
  • [article] bibtex
    A. M. Fassmer, A. Luque Ramos, C. Boiselle, S. Dreger, S. Helmer, und H. Zeeb, "[Tobacco Use and Utilization of Medical Services in Adolescence: An Analysis of the KiGGS Data]" Das Gesundheitswesen, vol. 81, iss. 1, pp. 17-23, 2019.
    @article{Fassmer.2019, abstract = {OBJECTIVE: In Germany, there is a lack of information on the correlation between tobacco use by adolescents and their utilization of medical care. The aim of this article is to identify possible early consequences of adolescent smoking. METHODS: We conducted a re-analysis of cross-sectional data of the baseline wave (2003-2006) of the German Health Survey for Children and Adolescents (KiGGS). To examine the association between current smoking status and utilization of medical care during the 12 months before the interview, prevalence of selected diseases was calculated, and stratified by smoking status. Besides, the proportion of adolescents who consulted a physician at least once and the total number of medical consultations were estimated. For the inpatient setting, information about the number of nights spent in a hospital was analyzed. In a multiple logistic regression, the association of smoking behavior with utilization of outpatient medical care was assessed, further adjusting for sociodemographic variables and comorbidities. RESULTS: The study population included 3 679 adolescents aged between 14 and 17 years. 49.1{\%} were female and 31.7{\%} were current smokers. Among smokers, there was an increased prevalence of cystitis (+87.0{\%}) and bronchitis (+50.0{\%}). Tobacco users consulted a general practitioner more frequently than non-smokers (+30.8{\%}). As far as medical specialists are concerned, there were more consultations with psychiatrists (+171.4{\%}) and psychologists (+94.4{\%}), but there was no increase in the total number of visits. Additionally, smoking adolescents were more frequently hospitalized (+26.5{\%}) and the stays were of longer duration (+19.7{\%}). There was a statistically significant association between current tobacco use and a greater utilization of medical care (OR=1.20; 95{\%}-CI: 1.02-1.40). CONCLUSIONS: Tobacco use among adolescents was associated with increased prevalence of certain diseases and a greater utilization of medical care. Nevertheless, whether there is a causal connection is still debatable. The KiGGS cohort study will provide opportunities to further clarify the observed association.},
      author = {Fassmer, Alexander Maximilian and {Luque Ramos},
      A. and Boiselle, C. and Dreger, S. and Helmer, S. and Zeeb, Hajo},
      year = {2019},
      title = {[Tobacco Use and Utilization of Medical Services in Adolescence: An Analysis of the KiGGS Data]},
      keywords = {*health services;*Tobacco Use;Adolescent;Child;Cohort Studies;Cross-Sectional Studies;Female;Germany;Health Surveys;Humans},
      pages = {17--23},
      volume = {81},
      number = {1},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Tabakkonsum und Inanspruchnahme medizinischer Leistungen im Jugendalter -- Eine Analyse der KIGGS Daten.},
      doi = {10.1055/s-0042-116590} }
  • [article] bibtex
    A. Gerka, M. Eichelberg, C. Stolle, C. Tietjen-Müller, S. Brinkmann-Gerdes, und A. Hein, "Interconnected living in a quarter for persons with dementia" Informatics for Health and Social Care, pp. 1-18, 2019.
    @article{Gerka.2019b, abstract = {Objective: In this work, we propose a new care concept for dementia patients in their own apartments: interconnected living in a quarter. We describe a technical setup that is comprised of a safety system and an activity detection system. The latter detects, processes and illustrates activities of daily living to help the quarter managers to provide appropriate interventions for persons with dementia in the quarter. Participants: The nine-month field study reported in this work was conducted in two quarters with eight participants. Methods: We evaluated different possibilities to determine activity indicators with the aim of providing information that enables the quarter managers to offer exactly the level of support needed by each individual patient. To evaluate the usefulness and the perception of the technical infrastructure, qualitative interviews with the dementia patients and the quarter managers were conducted. Results: The results indicate that the interconnected living concept helps to increase the safety of the dementia patients. Additionally, several activity indicators that help the quarter managers to offer the appropriate level of support to the dementia patients have been identified. Conclusion: The presented concept, which has been evaluated in a realworld-setting, constitutes a new holistic and cross-disciplinary dementia care approach.},
      author = {Gerka, Alexander and Eichelberg, Marco and Stolle, Christian and Tietjen-M{\"u}ller, Carmen and Brinkmann-Gerdes, Stefanie and Hein, Andreas},
      year = {2019},
      title = {Interconnected living in a quarter for persons with dementia},
      keywords = {ambient intelligence;Assistive technology;Dementia;interconnected living},
      pages = {1--18},
      volume = {0},
      number = {0},
      issn = {1753-8157},
      journal = {Informatics for Health and Social Care},
      doi = {10.1080/17538157.2019.1624968},
      file = {Gerka et al. - 2019 - Interconnected living in a quarter for persons with dementia:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2019 - Interconnected living in a quarter for persons with dementia.pdf:pdf} }
  • [article] bibtex
    M. Heupel-Reuter, T. Zieschang, F. Hoffmann, J. Bauer, und S. Voigt-Radloff, "[Interventions for improving palliative care for older people living in nursing care homes]" Z Gerontol Geriatr, vol. 52, iss. 8, pp. 758-760, 2019.
    @article{HeupelReuter.2019,
      author = {Heupel-Reuter, M. and Zieschang, Tania and Hoffmann, Falk and Bauer, J{\"u}rgen and Voigt-Radloff, S.},
      year = {2019},
      title = {[Interventions for improving palliative care for older people living in nursing care homes]},
      keywords = {*Nursing Homes;*Palliative Care;Aged;Aged, 80 and over;Homes for the Aged;Humans},
      pages = {758--760},
      volume = {52},
      number = {8},
      issn = {1435-1269 (Electronic) 0948-6704 (Linking)},
      journal = {Z Gerontol Geriatr},
      originalyear = {Interventionen zur Verbesserung der Palliativversorgung alterer Menschen, die in Pflegeeinrichtungen leben.},
      doi = {10.1007/s00391-019-01615-2},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31535188} }
  • [article] bibtex
    J. Höfer, F. Hoffmann, I. Kamp-Becker, C. Küpper, L. Poustka, S. Roepke, V. Roessner, S. Stroth, N. Wolff, und C. Bachmann, "Complementary and alternative medicine use in adults with autism spectrum disorder in Germany: results from a multi-center survey" BMC Psychiatry, vol. 19, iss. 1, p. 53, 2019.
    @article{Hofer.2019b, abstract = {BACKGROUND: Complementary and Alternative Medicine (CAM) is widely used both in the general population and for the treatment of somatic and psychiatric disorders. Studies on CAM use among patients with autism spectrum disorder (ASD) have so far only focused on children and adolescents. The aim of this study was to investigate patterns of CAM use among adults with ASD. METHODS: A questionnaire survey concerning current and lifetime use of CAM was distributed to adults with ASD between November 2015 and June 2016. Participants diagnosed by experienced clinicians using the current diagnostic gold standard were recruited from four ASD outpatient clinics in Germany. Questionnaire data was then linked to supplementary clinical data. RESULTS: The final sample consisted of 192 adults (response: 26.8{\%}) with a mean age of 31.5 years (80{\%} male; diagnoses: Asperger's syndrome (58{\%}), childhood autism (27{\%}), atypical autism (12{\%})). 45{\%} of the respondents stated that they were currently using or had used at least one CAM modality in their life. Among the participants with lifetime CAM use, almost half had used two or more different types of CAM. Alternative medical systems (e.g. homeopathy, acupuncture) were most frequently used, followed by mind-body interventions (e.g. yoga, biofeedback, animal assisted therapy). Overall, 20{\%} of respondents stated that they would like to try at least one listed CAM modality in the future. CONCLUSIONS: This is the first study on CAM use in adults with ASD, demonstrating considerable CAM use in this population. Given the popularity of CAM, patients should be informed about the effectiveness and potentially dangerous side effects of CAM treatments, as evidence for the majority of CAM methods in ASD is still limited.},
      author = {H{\"o}fer, J. and Hoffmann, Falk and Kamp-Becker, I. and K{\"u}pper, C. and Poustka, L. and Roepke, S. and Roessner, V. and Stroth, S. and Wolff, N. and Bachmann, C.},
      year = {2019},
      title = {Complementary and alternative medicine use in adults with autism spectrum disorder in Germany: results from a multi-center survey},
      keywords = {*Adults;*Autism;*Autism spectrum disorder;*cam;*complementary and alternative medicine;*Germany;*prevalence;*Surveys and Questionnaires;2015--607 N-MA;Acupuncture Therapy/methods/psychology;Adolescent;Adult;and by the concerned;Animal Assisted Therapy/methods;approved by the Commission for Impact Assessment Research and Ethics, Carl von;authors declare that they have no competing interests. PUBLISHER'S NOTE: Springer;Autism Spectrum Disorder/epidemiology/*psychology/*therapy;Berlin University:;Complementary Therapies/*methods/*psychology;Dresden University: reference number EK6012016). The data;Female;Germany/epidemiology;Humans;informed consent. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The;institutional affiliations.;institutional ethic committees (Heidelberg University: reference number;Male;Marburg University: reference number 148/15;Nature remains neutral with regard to jurisdictional claims in published maps and;Ossietzky University Oldenburg (reference number DRs. 23/2015);protection concept was additionally coordinated with the Data Protection Officer of;reference number 941/15;the Carl von Ossietzky University, Oldenburg. All participants provided written;Yoga/psychology;Young Adult},
      pages = {53},
      volume = {19},
      number = {1},
      issn = {1471-244x},
      journal = {BMC Psychiatry},
      doi = {10.1186/s12888-019-2043-5},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359789} }
  • [article] bibtex
    F. Hoffmann, A. Strautmann, und K. Allers, "Hospitalization at the end of life among nursing home residents with dementia: a systematic review" BMC Palliat Care, vol. 18, iss. 1, p. 77, 2019.
    @article{Hoffmann.2019c, abstract = {BACKGROUND: Half of nursing home residents (NHR) suffer from dementia. End-of-life hospitalizations are often burdensome in residents with dementia. A systematic review was conducted to study the occurrence of hospitalizations at the end of life in NHR with dementia and to compare these figures to NHR without dementia. METHODS: A systematic literature search in MEDLINE, CINAHL and Scopus was conducted in May 2018. Studies were included if they reported proportions of in-hospital deaths or hospitalizations of NHR with dementia in the last month of life. Two authors independently selected studies, extracted data, and assessed quality of studies. RESULTS: Nine hundred forty-five citations were retrieved; 13 studies were included. Overall, 7 studies reported data on in-hospital death with proportions ranging between 0{\%} in Canada and 53.3{\%} in the UK. Studies reporting on the last 30 days of life (n = 8) varied between 8.0{\%} in the Netherlands and 51.3{\%} in Germany. Two studies each assessed the influence of age and sex. There seem to be fewer end-of-life hospitalizations in older age groups. The influence of sex is inconclusive. All but one study found that at the end of life residents with dementia were hospitalized less often than those without (n = 6). CONCLUSIONS: We found large variations in end-of-life hospitalizations of NHR with dementia, probably being explained by differences between countries. The influence of sex and age might differ when compared to residents without dementia. More studies should compare NHR with dementia to those without and assess the influence of sex and age. TRIAL REGISTRATION: PROSPERO registration number CRD42018104263 .},
      author = {Hoffmann, Falk and Strautmann, A. and Allers, Katharina},
      year = {2019},
      title = {Hospitalization at the end of life among nursing home residents with dementia: a systematic review},
      keywords = {*Hospitalization;Death;Dementia/complications/psychology/*therapy;End-of-life care;Health services research;Hospital use;Humans;Long-term care;Nursing homes;Nursing Homes/organization {\&} administration;Terminal Care/methods/*standards},
      pages = {77},
      volume = {18},
      number = {1},
      issn = {1472-684x},
      journal = {BMC Palliat Care},
      doi = {10.1186/s12904-019-0462-1},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737675} }
  • [article] bibtex
    B. Kollhorst, K. Jobski, J. Krappweis, T. Schink, E. Garbe, und N. Schmedt, "Antidepressants and the risk of death in older patients with depression: A population-based cohort study" PLoS One, vol. 14, iss. 4, p. 0215289, 2019.
    @article{Kollhorst.2019, abstract = {BACKGROUND: Antidepressants are frequently used in older patients with depression, but little is known about the comparative safety of individual agents. The objective of the study was to determine the comparative risk of death of antidepressants in older patients with depression. METHODS AND FINDINGS: We carried out a cohort study from 2004 to 2015 utilizing the German Pharmacoepidemiological Research Database, a population-based database supplied by statutory health insurance providers covering approximately 17{\%} of the general population and all geographical regions. We included 376,846 patients aged 65+ years with a diagnosis of depression who initiated treatment with one of 13 antidepressants (ADs). In total 27,019 patients died during follow-up corresponding to a rate of 119.7 per 1,000 person years. We used proportional hazards models to estimate hazard ratios (HRs) with 95{\%} confidence intervals (CIs) for the risk of death for twelve ADs compared to citalopram. In the primary analysis, we found an increased risk of death associated with the use of amitriptyline (HR 1.15, 95{\%}CI: 1.10-1.20). However, opipramol, trimipramine, doxepin, mirtazapine, fluoxetine, paroxetine, duloxetine, venlafaxine, and St. John's wort were found to be associated with a lower risk of death. The increased risk of amitriptyline diminished after exclusion of patients with a history of cancer (HR 0.88, 95{\%}CI: 0.82-0.94) and after high-dimensional propensity score (HdPS) adjustment (HR 1.04, 95{\%}CI: 0.95-1.14). In older patients and in those with dementia, differences in risk between most individual ADs and citalopram were smaller. After adjustment by HdPS, the decreased risks for fluoxetine, paroxetine, venlafaxine and mirtazapine compared to citalopram disappeared. CONCLUSIONS: This study suggests that ADs recommended as first-line treatment in patients with depression have a similar safety profile with regard to the risk of death, especially in very old patients and in those with dementia. Further research is needed to investigate the risk of death for individual ADs in specific subgroups such as patients with cancer or cardiovascular disease.},
      author = {Kollhorst, Bianca and Jobski, Kathrin and Krappweis, J. and Schink, Tania and Garbe, E. and Schmedt, N.},
      year = {2019},
      title = {Antidepressants and the risk of death in older patients with depression: A population-based cohort study},
      keywords = {Aged;Antidepressive Agents/administration {\&} dosage/*adverse effects;Cohort Studies;Depression/*drug therapy/*mortality;Female;Follow-Up Studies;Germany/epidemiology;Humans;Male;Middle Aged;Risk Factors},
      pages = {e0215289},
      volume = {14},
      number = {4},
      issn = {1932-6203 (Electronic) 1932-6203 (Linking)},
      journal = {PLoS One},
      doi = {10.1371/journal.pone.0215289},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464187},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30986235} }
  • [article] bibtex
    A. Pulst, A. M. Fassmer, und G. Schmiemann, "Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research" BMC Geriatrics, vol. 19, iss. 1, p. 155, 2019.
    @article{Pulst.2019, abstract = {BACKGROUND: Nursing home residents (NHR) are characterized by increasing frailty, multimorbidity and care dependency. These conditions result in frequent hospital transfers which can lead to negative effects on residents' health status and are often avoidable. Reasons for emergency department (ED) visits or hospital admissions are complex. Prior research indicated factors influencing transfer decisions in view of nursing staff and general practitioners. The aim of this systematic review is to explore how family members experience and influence transfers from nursing home (NH) to hospital and how they are involved in the transfer decision. METHODS: A systematic literature search was performed in Medline via PubMed, Ebsco Scopus and CINAHL in May 2018. Studies were eligible if they contained information a) about the decision to transfer NHR to hospital and b) the experiences or influence of family members. The review followed Joanna Briggs Institute's (JBI) approach for qualitative systematic reviews. Screening, selection and quality appraisal of studies were performed independently by two reviewers. Synthesis of qualitative data was conducted through meta-aggregation. RESULTS: After screening of n = 2863 articles, in total n = 10 qualitative studies were included in the review. Results indicate that family members of NHR experience decision-making before hospitalization differently. They mainly reported NH-related, hospital-related, and family/resident-related factors influencing the transfer decision. The involvement of family members in the decision-making process varies - from no involvement to insistence on a decision in favor of their personal preferences. However, hospital transfer decisions and other treatment decisions (e.g. advance care planning (ACP) discussions) were commonly discussed with physicians and nurses. Conflicts between family members and healthcare providers mostly arose around the interpretation of resident's best interest. In general, family members perceive discussions as challenging thus leading to emotional stress and discomfort. CONCLUSION: The influence of NHR family members concerning hospital transfer decisions varies. Family members are an important link for communication between resident and medical staff and for communication between NH and hospital. Interventions aiming to reduce hospitalization rates have to take these findings into account.},
      author = {Pulst, Alexandra and Fassmer, Alexander Maximilian and Schmiemann, Guido},
      year = {2019},
      title = {Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research},
      keywords = {*Decision Making;*Family;*Hospitalization;*nursing home;*Patient transfer;*Qualitative evidence synthesis;*Qualitative Research;Family/*psychology;Health Personnel/psychology/standards;Hospitals/standards;Humans;Nursing Homes/*standards;Patient Transfer/methods/*standards;Skilled Nursing Facilities/standards},
      pages = {155},
      volume = {19},
      number = {1},
      issn = {1471-2318},
      journal = {BMC Geriatrics},
      doi = {10.1186/s12877-019-1170-7},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31164101},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549333} }
  • [article] bibtex
    I. Redeker, J. Callhoff, F. Hoffmann, H. Haibel, J. Sieper, A. Zink, und D. Poddubnyy, "Determinants of diagnostic delay in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data" Rheumatology (Oxford), vol. 58, iss. 9, pp. 1634-1638, 2019.
    @article{Redeker.2019, abstract = {OBJECTIVES: The objective of this study was to assess the current diagnostic delay in axial SpA (axSpA) and to analyse factors associated with it. METHODS: A stratified sample of subjects with a diagnosis of axSpA (International Classification of Diseases, 10th Revision code M45) was drawn from health insurance data in Germany and was questioned on disease-related, lifestyle and socio-economic characteristics. The diagnostic delay was calculated as the time from back pain onset until a diagnosis of axSpA. A multivariable linear regression analysis was performed to explore factors associated with the diagnostic delay. RESULTS: Among 1677 patients with axSpA included in the analysis, the mean diagnostic delay was 5.7 years (median 2.3). Of those, 407 patients were diagnosed in 1996-2005 and 484 patients in 2006-2015. The mean diagnostic delay was not substantially different in both periods: 6.3 years (median 2.6) and 7.4 (2.7), respectively. Multivariable linear regression revealed that female sex [beta = 1.85 (95{\%} CI 1.06, 2.65)], negative HLA-B27 status [beta = 3.61 (95{\%} CI 2.07, 5.14)], presence of psoriasis [beta = 1.40 (95{\%} CI 0.08, 2.73)] and younger age at symptom onset [beta = 1.91 (95{\%} CI 1.53, 2.29)] were factors associated with a longer diagnostic delay. CONCLUSION: The diagnostic delay in axSpA is still unacceptably long. Patients who are female, young at symptom onset, HLA-B27 negative or have psoriasis have a longer diagnostic delay. Specific referral strategies might be necessary in order to decrease the diagnostic delay in patients presenting with these characteristics.},
      author = {Redeker, Imke and Callhoff, Johanna and Hoffmann, Falk and Haibel, Hildrun and Sieper, Joachim and Zink, Angela and Poddubnyy, Denis},
      year = {2019},
      title = {Determinants of diagnostic delay in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data},
      keywords = {*axial spondyloarthritis;*diagnostic delay;Adolescent;Adult;Age Factors;Aged;Aged, 80 and over;Back Pain/etiology;Child;Delayed Diagnosis;Educational Status;Female;Germany;Humans;Male;Middle Aged;Patient Reported Outcome Measures;Risk Factors;Sex Factors;Spondylarthritis/complications/*diagnosis;Spondylitis, Ankylosing/complications/diagnosis;Time Factors;Young Adult},
      pages = {1634--1638},
      volume = {58},
      number = {9},
      issn = {1462-0332 (Electronic) 1462-0324 (Linking)},
      journal = {Rheumatology (Oxford)},
      doi = {10.1093/rheumatology/kez090},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30903141} }
  • [article] bibtex
    T. Rombey, K. Allers, T. Mathes, F. Hoffmann, und D. Pieper, "A descriptive analysis of the characteristics and the peer review process of systematic review protocols published in an open peer review journal from 2012 to 2017" BMC Med Res Methodol, vol. 19, iss. 1, p. 57, 2019.
    @article{Rombey.2019, abstract = {BACKGROUND: An a priori design is essential to reduce the risk of bias in systematic reviews (SRs). To this end,
      authors can register their SR with PROSPERO, and/or publish a SR protocol in an academic journal. The latter has the advantage that the manuscript for the SR protocol is usually peer-reviewed. However, since authors ought not to begin/continue the SR before their protocol has been accepted for publication, it is crucial that SR protocols are processed in a timely manner. Our main aim was to descriptively analyse the peer review process of SR protocols published in 'BMC Systematic Reviews' from 2012 to 2017. METHODS: We systematically searched MEDLINE via PubMed for all SR protocols published in 'BMC Systematic Reviews' between 2012 and 2017, except for protocols for overviews, scoping reviews or realist reviews. Data were extracted from the SR protocols and Open Peer Review reports. For each round of peer review, two researchers judged the extent of revision (minor/major) based on the reviewer reports. Their content was further investigated by two researchers in a random 10{\%}-sample using PRISMA-P as a guideline. All data were analysed descriptively. RESULTS: We identified 544 eligible protocols published in 'BMC Systematic Reviews' between 2012 and 2017. Of those, 485 (89.2{\%}) also registered the SR in PROSPERO, the majority (87.4{\%}) before first submission of the manuscript for the SR protocol (median 49 days). The absolute number of published SR protocols increased from 2012 to 2017 (21 vs 145 protocols), as did the median processing time (61 vs 142 days from submission to acceptance) and the proportion of protocols requiring a major revision after first peer review (19.1{\%} vs 52.4{\%}). Reviewer comments most frequently addressed the PRISMA-P item 'Eligibility criteria'. Overall, 76.0{\%} of the reviewer comments suggested more transparency. CONCLUSIONS: The number of published SR protocols increased over the years, but so did the processing time. In 2017, it took several months from submission to acceptance, which is critical from an author's perspective. New models of peer review such as post publication peer review for SR protocols should be investigated. This could probably be realized with PROSPERO.},
      author = {Rombey, Tanja and Allers, Katharina and Mathes, T. and Hoffmann, Falk and Pieper, Dawid},
      year = {2019},
      title = {A descriptive analysis of the characteristics and the peer review process of systematic review protocols published in an open peer review journal from 2012 to 2017},
      keywords = {*Meta-analysis;*Peer Review;*prospero;*Protocol;*Systematic review;*Systematic Reviews as Topic;Bias;Humans;Publications/*standards/statistics {\&} numerical data;Research Design/*standards;Research Report/*standards},
      pages = {57},
      volume = {19},
      number = {1},
      issn = {1471-2288 (Electronic) 1471-2288 (Linking)},
      journal = {BMC Med Res Methodol},
      doi = {10.1186/s12874-019-0698-8},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415341},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30866832} }
  • [article] bibtex
    I. Seeger, L. Kreienmeyer, F. Hoffmann, und M. H. Freitag, "Cross-sectional study in an out-of-hours primary care centre in northwestern Germany - patient characteristics and the urgency of their treatment" BMC Fam Pract, vol. 20, iss. 1, p. 41, 2019.
    @article{Seeger.2019, abstract = {BACKGROUND: Due to the increasing number of non-urgent visits to emergency departments, it is becoming increasingly important to also investigate emergency care in out-of-hours (OOH) primary care. The aim of this study was to provide an insight into the care structures of an OOH primary care centre, to evaluate the reasons for encounter (RFE) and to assess the urgency of the treatment from the physicians´ point of view. METHODS: In the summer of 2017, we conducted a cross-sectional study over four weeks in the OOH primary care centre of Oldenburg, a city in Lower Saxony with about 160,000 inhabitants. We collected socio-demographic data, RFE and the duration of the complaints. The International Classification for Primary Care 2nd Edition (ICPC-2) was used to categorize symptoms. The attending physicians supplemented information on further treatment (including hospitalization) and the urgency of consultation in the OOH primary care centre. RESULTS: A total of 892 of the 1098 OOH patients which were visiting the OOH primary care centre took part in the study (participation: 81.2{\%}). More than half of the patients were between 18 and 39 years old. A quarter of all RFE named by study participants were in the ICPC-2 category {\textquotedbl}skin{\textquotedbl}. More than 60{\%} of patients had the symptoms for more than two days before visiting the OOH primary care centre. In 34.5{\%} of all cases no medication was prescribed and one in six patients received further diagnostic tests such as urinalysis and blood tests (15.8{\%}). From the physicians' point of view, 26.3{\%} of all study participants could have been treated by the family doctor during the regular consultation hours. CONCLUSION: The study shows that in the OOH primary care centre about a quarter of all patients could have waited until regular consultation hours. Mostly young patients used the easily accessible and free care in the OOH primary care centre. Further studies are necessary to better understand the individual reasons of patients to use the OOH primary care centre.},
      author = {Seeger, Insa and Kreienmeyer, L. and Hoffmann, Falk and Freitag, Michael H.},
      year = {2019},
      title = {Cross-sectional study in an out-of-hours primary care centre in northwestern Germany - patient characteristics and the urgency of their treatment},
      keywords = {*Non-urgent;*Out-of-hours primary care (OOH primary care);*Physicians´ perspective;*Reason for encounter (RFE);Adolescent;Adult;After-Hours Care/*statistics {\&} numerical data;Aged;Ambulatory Care;Child;Child, Preschool;claims in published maps and institutional affiliations.;COMPETING INTERESTS: The authors declare that they have no competing interests.;Digestive System Diseases;ethics committee of the University of Oldenburg (reference no. 2017--032). All;Female;Germany;Humans;Infant;Infant, Newborn;Insect Bites and Stings;Male;Middle Aged;Musculoskeletal Diseases;participants had to give written informed consent. Parental consent was obtained for;Primary Health Care/*statistics {\&} numerical data;PUBLISHER'S NOTE: Springer Nature remains neutral with regard to jurisdictional;Respiratory Tract Diseases;Severity of Illness Index;Skin Diseases;study participants under 18 years of age. CONSENT FOR PUBLICATION: Not applicable.;Tick Bites;Young Adult},
      pages = {41},
      volume = {20},
      number = {1},
      issn = {1471-2296},
      journal = {BMC Fam Pract},
      doi = {10.1186/s12875-019-0929-4},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399868} }
  • [article] bibtex
    J. Tillmann, J. M. Just, R. Schnakenberg, K. Weckbecker, B. Weltermann, und E. Münster, "Challenges in diagnosing dementia in patients with a migrant background - a cross-sectional study among German general practitioners" BMC Fam Pract, vol. 20, iss. 1, p. 34, 2019.
    @article{Tillmann.2019, abstract = {BACKGROUND: Diagnosing dementia, a syndrome affecting 35.6 million people worldwide, can be challenging, especially in patients with a migrant background. Language barriers and language-based diagnostic tools, cultural differences in the perception of the syndrome as well as restricted access to healthcare can influence medical care. For the first time in Germany, this study investigates whether German general practitioners (GPs) feel prepared to meet the diagnostic needs of these patient groups and whether there are challenges and support needs. METHODS: A cross-sectional study among a random sample of 982 general practitioners in Germany was conducted from October 2017 to January 2018 (response rate: 34.5{\%}). A self-developed, written, standardised questionnaire was used. Descriptive statistics as well as multiple logistic regression analyses were performed using data of 326 GPs. RESULTS: Ninety-six percent of GPs reported having experienced barriers at least once. Uncertainties in diagnosing dementia in patients with a migrant background were indicated by 70.9{\%}. There was no significant association between uncertainties in diagnosing dementia and GPs' sociodemographic characteristics. The most frequently reported barriers were language barriers that affected or prevented diagnostics (89.3{\%}) and information deficits in patients with a migrant background (59.2{\%}). Shameful interaction or lack of acceptance of the syndrome was also common (55.5{\%}). A demand for more information about the topic was expressed by 70.6{\%} of GPs. CONCLUSIONS: Public health measures supporting GPs in their interaction with patients with a migrant background as well as information and services for dementia patients are needed. Efforts to facilitate access to interpreting services and to focus on people with a migrant background in healthcare are necessary. TRIAL REGISTRATION: German Clinical Trials Register: DRKS00012503 , date of registration: 05/09/2017 (German Institute of Medical Documentation and Information. German Clinical Trials Register (DRKS) 2017). Clinical register of the study coordination office of the University hospital of Bonn: ID530, date of registration: 05/09/2017 (Universit{\"a}tsklinikum Bonn. Studienzentrum. UKB-Studienregister 2017).},
      author = {Tillmann, J. and Just, J. M. and Schnakenberg, Rieke and Weckbecker, Klaus and Weltermann, B. and M{\"u}nster, E.},
      year = {2019},
      title = {Challenges in diagnosing dementia in patients with a migrant background - a cross-sectional study among German general practitioners},
      keywords = {*Attitude of Health Personnel;*Communication Barriers;*Culture;*Dementia;*Diagnostics;*Emigrants and Immigrants;*General practitioner;*General Practitioners;*gp;*Migration;*Public health;Attitude to Health;competing interests. PUBLISHER'S NOTE: Springer Nature remains neutral with regard;consent to participate is not applicable since it was voluntary, no identifiable;Cross-Sectional Studies;Dementia/*diagnosis;Ethics Committee reviewed and approved this study (reference number: 251/17). A;Female;Germany;Humans;Logistic Models;Male;material is published and a participation is regarded as an acceptance. CONSENT FOR;Middle Aged;PUBLICATION: No identifiable material is published and therefore no consent to;publish is required. COMPETING INTERESTS: The authors declare that they have no;Shame;Surveys and Questionnaires;to jurisdictional claims in published maps and institutional affiliations.},
      pages = {34},
      volume = {20},
      number = {1},
      issn = {1471-2296},
      journal = {BMC Fam Pract},
      doi = {10.1186/s12875-019-0920-0},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388491} }
  • [incollection] bibtex
    S. Hellmers, S. Lau, R. Diekmann, L. Dasenbrock, T. Kromke, J. Bauer, S. Fudickar, und A. Hein, "Evaluation of Power-Based Stair Climb Performance via Inertial Measurement Units" in Biomedical Engineering Systems and Technologies, Cliquet, A., Wiebe, S., Anderson, P., Saggio, G., Zwiggelaar, R., Gamboa, H., Fred, A., und Bermúdez i Badia, S., Eds., Cham: Springer International Publishing, 2019, vol. 1024, pp. 238-261.
    @incollection{Hellmers.2019b,
      author = {Hellmers, Sandra and Lau, Sandra and Diekmann, Rebecca and Dasenbrock, Lena and Kromke, Tobias and Bauer, J{\"u}rgen and Fudickar, Sebastian and Hein, Andreas},
      title = {Evaluation of Power-Based Stair Climb Performance via Inertial Measurement Units},
      pages = {238--261},
      volume = {1024},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-030-29195-2},
      series = {Communications in Computer and Information Science},
      editor = {Cliquet, Alberto and Wiebe, Sheldon and Anderson, Paul and Saggio, Giovanni and Zwiggelaar, Reyer and Gamboa, Hugo and Fred, Ana and {Berm{\'u}dez i Badia},
      Sergi},
      booktitle = {Biomedical Engineering Systems and Technologies},
      year = {2019},
      address = {Cham},
      doi = {10.1007/978-3-030-29196-9{\textunderscore }13} }
  • [article] bibtex
    H. Haibel, I. Redeker, A. Zink, J. Callhoff, U. Marschall, F. Hoffmann, J. Sieper, und D. Poddubnyy, "[Health care and disease burden in persons with axial spondyloarthritis in Germany]" Z Rheumatol, vol. 78, iss. 9, pp. 865-874, 2019.
    @article{Haibel.2019, abstract = {BACKGROUND: Only very few data are available on the comprehensive care in patients with axial spondylarthritis (axSpA), one of the most frequent inflammatory rheumatic disease. OBJECTIVE: Description of the comprehensive care and common prescription patterns of medications and other therapies in patients with axSpA depending on the type of medical care by rheumatologists or nonrheumatologists. METHODS: A cross-sectional analysis was performed based on claims data of the BARMER health insurance company (in 2015) and a questionnaire, which was sent to a representative sample of patients with axSpA (International Classification of Diseases, 10th revision, German modification, ICD-10-GM, code M45) aged 18-79 years. A stratified sample of 5000 patients was used. The patients received a postal questionnaire including questions regarding the disease, health-related and psychological parameters and socioeconomic factors. Claims data consisted of demographic factors, medicinal and nonmedicinal treatment and the extra-articular manifestations inflammatory bowel disease, psoriasis and uveitis. RESULTS: A total of 1741 patients (mean age 55.9 years, female 46.4{\%},
      86.2{\%} Human Leucocyte Antigen[HLA]-B27 positive) confirmed the diagnosis and answered the questionnaire. The mean Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) was 4.5 and the mean Bath Ankylosing Spondylitis Functional Index (BASFI) 4.1. Of the patients 46{\%} were treated by rheumatologists. There was a substantial difference between patients in rheumatological care and those who were not in rheumatological care regarding prescriptions for drug treatment of axSpA (91.8{\%} versus 66.4{\%}). This difference was especially prominent for prescriptions of biologic disease-modifying antirheumatic drugs: 34.1{\%} of patients in rheumatological care versus 3.1{\%} of patients treated by nonrheumatologists (p{\textless} 0.0001), despite similar disease activity in both groups. CONCLUSION: The data show that the majority of patients diagnosed with axSpA did not receive regular care from rheumatologists. This seemed to be associated with insufficient medicinal care at least in some of these patients.},
      author = {Haibel, Hildrun and Redeker, Imke and Zink, Angela and Callhoff, Johanna and Marschall, Ursula and Hoffmann, Falk and Sieper, Joachim and Poddubnyy, Denis},
      year = {2019},
      title = {[Health care and disease burden in persons with axial spondyloarthritis in Germany]},
      keywords = {*Quality of Health Care;*Spondylarthritis/therapy;*Spondylitis, Ankylosing;Adolescent;Adult;Aged;Ankylosing spondylitis;Biological Products/*therapeutic use;Burden of disease;Cross-Sectional Studies;Diagnostics;Drug treatment;Female;Germany;Health insurance data;HLA-B27 Antigen/blood;Humans;Male;Medical care;Middle Aged;Rheumatology/*standards;Severity of Illness Index;Surveys and Questionnaires;Young Adult},
      pages = {865--874},
      volume = {78},
      number = {9},
      issn = {0340-1855},
      journal = {Z Rheumatol},
      originalyear = {Gesundheitsversorgung und Krankheitslast bei Personen mit axialer Spondyloarthritis in Deutschland.},
      doi = {10.1007/s00393-019-0650-7},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31172266} }
  • [article] bibtex
    H. Jacobs, F. Hoffmann, J. Callhoff, A. Postler, J. Saam, A. Zink, K. P. Gunther, und J. Goronzy, "[Utilization of individual out-of-pocket health services (IGeL) in persons with osteoarthritis in Germany : Results of a survey from the PROCLAIR study]" Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, vol. 62, iss. 8, pp. 1013-1019, 2019.
    @article{Jacobs.2019, abstract = {BACKGROUND: Little is known about the utilization of individual health services performed by a physician (IGeL) and the services and supplements provided outside a doctor's office (MuPaP) for osteoarthritis patients. OBJECTIVES: The aims of this study are to analyze the use of osteoarthritis-specific IGeL and MuPaP as well as predictors for their utilization. MATERIALS AND METHODS: For this cross-sectional study, claims data was used to identify all persons with hip, knee, or polyarticular osteoarthritis in 2014 (n= 657,807). A random sample (n= 8995) was sent a questionnaire about their usage of IGeL and MuPaP. Furthermore, the type of physicians conducting or recommending services was evaluated. Applying multivariable logistic regression, predictors associated with the utilization of IGeL, MuPaP, and overall individual health services were analyzed. RESULTS: After validating the data and osteoarthritis diagnosis, 2363 persons were enrolled (mean age: 65.5 years, 72{\%} female). In the last 12 months, 39{\%} of patients had used at least one IGeL (MuPaP: 76{\%}), with 86{\%} being primarily performed by orthopedists (MuPaP: 88{\%} patient self-motivated). Knee osteoarthritis was associated with increased utilization of IGeL. Having female gender, higher income, residence in Western Germany, higher disease burden, and lower satisfaction with the healthcare system were influences on the use of overall individual health services. CONCLUSIONS: Since patients with high disease burden in particular tend to use these therapies with varying treatment success, detailed information, especially about the risks and existing evidence, should be a prerequisite for trustworthy doctor-patient relationships.},
      author = {Jacobs, Hannes and Hoffmann, Falk and Callhoff, Johanna and Postler, Anne and Saam, Joachim and Zink, Angela and Gunther, K. P. and Goronzy, Jens},
      year = {2019},
      title = {[Utilization of individual out-of-pocket health services (IGeL) in persons with osteoarthritis in Germany : Results of a survey from the PROCLAIR study]},
      keywords = {*Cost of Illness;Administrative Claims, Healthcare;Aged;Arthroplasty, Replacement, Hip/statistics {\&} numerical data;Arthroplasty, Replacement, Knee/statistics {\&} numerical data;Cross-Sectional Studies;Data linkage;Female;Germany;Health Expenditures/*statistics {\&} numerical data;Health Services Accessibility;Health services research;Health-services research;Humans;Insurance Claim Reporting/*statistics {\&} numerical data;Male;Osteoarthritis;Osteoarthritis, Hip/*therapy;Osteoarthritis, Knee/*therapy;Osteoarthritis/diagnosis/*therapy;Out-of-pocket payments;Social Class;Socioeconomic status;Surveys and Questionnaires},
      pages = {1013--1019},
      volume = {62},
      number = {8},
      issn = {1437-1588 (Electronic) 1436-9990 (Linking)},
      journal = {Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz},
      originalyear = {Inanspruchnahme von individuellen Gesundheitsleistungen (IGeL) bei Arthrose in Deutschland : Ergebnisse einer Befragung im Rahmen der PROCLAIR-Studie.},
      doi = {10.1007/s00103-019-02986-y},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31273415} }
  • [article] bibtex
    H. Jacobs, J. Callhoff, F. Hoffmann, A. Zink, und K. Albrecht, "[Non-drug treatment of rheumatoid arthritis : An analysis of claims data and a survey of insured persons (Project PROCLAIR)]" Z Rheumatol, vol. 78, iss. 2, pp. 119-126, 2019.
    @article{Jacobs.2019b, abstract = {BACKGROUND: Only small amounts of data are available on the prescription frequency of physical therapies (PT) for patients with rheumatoid arthritis (RA). OBJECTIVE: The aim of the study was to evaluate prescription frequencies of PT considering functional status and sociodemographic factors. MATERIAL AND METHODS: A total of 98,963 adults diagnosed with RA in 2013 were identified in claims data from the BARMER health insurance. A questionnaire was sent to a representative sample of 6193 people requesting information on the disease status. Of these 2535 persons were included who agreed to the linking of the questionnaire and claims data and who confirmed a diagnosis of RA. From the routine claims data the prescription of PT and occupational therapy as well as the medical discipline of the prescribing physician were analyzed. Multivariable logistic regression was conducted to determine which variables (age, sex, M05/M06 diagnosis, residential area, income, functional status and rheumatological care) were associated with the use of PT. RESULTS: In 2015 a total of 47{\%} of the study population received PT (35{\%} physiotherapy, 15{\%} thermotherapy, 15{\%} manual therapy, 2{\%} electrotherapy and 6{\%} massage) and 3{\%} occupational therapy. Of the PT prescriptions 37{\%} were issued by general practitioners, 27{\%} by orthopedists and 18{\%} by rheumatologists. Women and persons living in the eastern states of Germany and patients with high functional impairment were prescribed PT more often. Income, educational status, seropositivity and rheumatological care did not have any influence on the frequency of prescription of PT. CONCLUSION: There are deficits in the outpatient prescription of PT but without indications of an undersupply of population groups due to low socioeconomic status. In contrast to the prescription of disease-modifying antirheumatic drug (DMARD) treatment, PT is predominantly prescribed by general practitioners.},
      author = {Jacobs, Hannes and Callhoff, Johanna and Hoffmann, Falk and Zink, Angela and Albrecht, Katinka},
      year = {2019},
      title = {[Non-drug treatment of rheumatoid arthritis : An analysis of claims data and a survey of insured persons (Project PROCLAIR)]},
      keywords = {*Arthritis, Rheumatoid/therapy;*Physical Therapy Modalities;Adult;Antirheumatic Agents;Female;Germany;Health services research;Humans;Male;Occupational therapy;Physical therapy;Physiotherapy;Rheumatoid arthritis;Rheumatology;Surveys and Questionnaires},
      pages = {119--126},
      volume = {78},
      number = {2},
      issn = {0340-1855},
      journal = {Z Rheumatol},
      originalyear = {Nichtmedikamentose Versorgung der rheumatoiden Arthritis : Eine Analyse von Abrechnungsdaten und einer Versichertenbefragung (Projekt PROCLAIR).},
      doi = {10.1007/s00393-018-0567-6},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30478638} }
  • [article] bibtex
    S. March, S. Andrich, J. Drepper, D. Horenkamp-Sonntag, A. Icks, P. Ihle, J. Kieschke, B. Kollhorst, B. Maier, I. Meyer, G. Muller, C. Ohlmeier, D. Peschke, A. Richter, M. L. Rosenbusch, N. Scholten, M. Schulz, C. Stallmann, E. Swart, S. Wobbe-Ribinski, A. Wolter, J. Zeidler, und F. Hoffmann, "[Good Practice Data Linkage]" Das Gesundheitswesen, vol. 81, iss. 8-09, pp. 636-650, 2019.
    @article{March.2019, abstract = {Individual data linkage of different data sources for research purposes is being increasingly used in Germany in recent years. However, generally accepted methodological guidance is missing. The aim of this article is to define such methodological standards for research projects. Another aim is to provide readers with a checklist for critical appraisal of research proposals and articles. Since 2016, an expert panel of members of different German scientific societies have worked together and developed 7 guidelines with a total of 27 practical recommendations. These recommendations include (1) research aims, questions, data sources and resources, (2) infrastructure and data flow, (3) data privacy, (4) ethics, (5) key variables and type of linkage, (6) data validation/quality assurance and (7) long-term use for future research questions. The authors provide a rationale for each recommendation. Future revisions will include any new developments in science and data privacy.},
      author = {March, Stefanie and Andrich, Silke and Drepper, Johannes and Horenkamp-Sonntag, Dirk and Icks, Andrea and Ihle, Peter and Kieschke, Joachim and Kollhorst, Bianca and Maier, Birga and Meyer, Ingo and Muller, G. and Ohlmeier, C. and Peschke, D. and Richter, A. and Rosenbusch, M. L. and Scholten, Nadine and Schulz, M. and Stallmann, C. and Swart, E. and Wobbe-Ribinski, S. and Wolter, A. and Zeidler, J. and Hoffmann, Falk},
      year = {2019},
      title = {[Good Practice Data Linkage]},
      keywords = {*Information Storage and Retrieval;*Research Design;Germany;Humans},
      pages = {636--650},
      volume = {81},
      number = {8-09},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Gute Praxis Datenlinkage (GPD).},
      doi = {10.1055/a-0962-9933},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31394579} }
  • [article] bibtex
    A. Nguyen, K. Weckbecker, L. Radbruch, und R. Schnakenberg, "[Information brochure for relatives of people with severe illness - acceptance and feasibility]" MMW Fortschr Med, vol. 161, iss. Suppl 6, pp. 3-8, 2019.
    @article{Nguyen.2019, abstract = {BACKGROUND: Family members of patients with severe illness are burdened with the care and participation in challenging decisions regarding medical treatment and care in addition to the challenges of their own lives. They express a wish for low-threshold support services. However, there are few publications on targeted interventions for the support of family members of patients with a serious illness. METHOD: An information brochure was developed on the basis of a systematic review and its feasibility and acceptance were tested with an evaluation sheet, handed out to family members in 3 different settings (3 palliative care units, 21 family practices, and 2 home palliative care services) over a period of 6 weeks. Satisfaction was measured using a 5-point Likert scale (1 = very satisfied, 5 = not satisfied at all). To assess the acceptance of the brochure the participants were asked about their willingness to read. The benefit was judged on questions of information gain. In addition, deficiencies could be named and suggestions for improvement could be made. RESULTS: Overall, 27 evaluation sheets were analysed. 93{\%} of the participating relatives read the whole brochure. 63{\%} of the relatives were satisfied or very satisfied with the flyer (median 2 = satisfied). 70{\%} of the relatives said they had received new information. CONCLUSIONS: In this feasibility study, the acceptance and usefulness of the information flyer for a large number of relatives was confirmed. Such an information flyer thus provides a low-threshold supplement to the support of families in the care at the end of life.},
      author = {Nguyen, A. and Weckbecker, Klaus and Radbruch, L. and Schnakenberg, Rieke},
      year = {2019},
      title = {[Information brochure for relatives of people with severe illness - acceptance and feasibility]},
      keywords = {*Pamphlets;*Professional-Family Relations;Family/psychology;Feasibility Studies;feasibility study;Home Care Services;Humans;Information Dissemination/*methods;information for relatives;Palliative Care;severe illness},
      pages = {3--8},
      volume = {161},
      number = {Suppl 6},
      issn = {1613-3560 (Electronic) 1438-3276 (Linking)},
      journal = {MMW Fortschr Med},
      originalyear = {Informationsflyer fur Angehorige von Menschen mit schwerer Erkrankung : Akzeptanz und Machbarkeit.},
      doi = {10.1007/s15006-019-0918-5},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/31587170} }
  • [article] bibtex
    L. Gabrys, C. Schmidt, C. Heidemann, J. Baumert, A. Teti, Y. Du, R. Paprott, T. Ziese, W. Banzer, und M. Böhme, "Diabetes-Surveillance in Deutschland--Auswahl und Definition von Indikatoren" , 2018.
    @article{Gabrys.2018,
      author = {Gabrys, Lars and Schmidt, Christian and Heidemann, Christin and Baumert, Jens and Teti, Andrea and Du, Yong and Paprott, Rebecca and Ziese, Thomas and Banzer, Winfried and B{\"o}hme, Michael},
      year = {2018},
      title = {Diabetes-Surveillance in Deutschland--Auswahl und Definition von Indikatoren} }
  • [article] bibtex
    D. Hüske-Kraus, M. Wilken, und R. Röhrig, "Measuring Alarm System Quality in Intensive Care Units" Proceedings of Zukunft der Pflege-Innovative Technologien für die Pflege, 2018.
    @article{HuskeKraus.2018,
      author = {H{\"u}ske-Kraus, Dirk and Wilken, Marc and R{\"o}hrig, Rainer},
      year = {2018},
      title = {Measuring Alarm System Quality in Intensive Care Units},
      journal = {Proceedings of Zukunft der Pflege-Innovative Technologien f{\"u}r die Pflege} }
  • [article] bibtex
    A. Gerka, M. Pfingsthorn, C. Lüpkes, K. Sparenberg, M. Frenken, C. Lins, und A. Hein, "Detecting the Number of Persons in the Bed Area to Enhance the Safety of Artificially Ventilated Persons" 2018 IEEE 20th International Conference on e-Health Networking, Applications and Services (Healthcom), 2018.
    @article{Gerka.2018b,
      author = {Gerka, Alexander and Pfingsthorn, Max and L{\"u}pkes, Christian and Sparenberg, Kevin and Frenken, Melina and Lins, Christian and Hein, Andreas},
      year = {2018},
      title = {Detecting the Number of Persons in the Bed Area to Enhance the Safety of Artificially Ventilated Persons},
      journal = {2018 IEEE 20th International Conference on e-Health Networking, Applications and Services (Healthcom)},
      file = {Gerka et al. - 2018 - Detecting the Number of Persons in the Bed Area to Enhance the Safety of Artificially Ventilated Persons:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2018 - Detecting the Number of Persons in the Bed Area to Enhance the Safety of Artificially Ventilated Persons.pdf:pdf} }
  • P. Gliesche, C. Kowalski, T. Krahn, S. Drolshagen, A. Hein, und M. Pfingsthorn, "A qualitative survey on challenges and use-cases for robotic assistants in nursing care" , 2018.
    @article{Gliesche.2018,
      author = {Gliesche, Pascal and Kowalski, Christian and Krahn, Tobias and Drolshagen, Sandra and Hein, Andreas and Pfingsthorn, Max},
      year = {2018},
      title = {A qualitative survey on challenges and use-cases for robotic assistants in nursing care},
      url = {https://www.idiap.ch/workshop/iros2018/files/08f-2018-rfalws-survey-use-cases-final.pdf},
      file = {Gliesche et al. - 2018 - A qualitative survey on challenges and use-cases for robotic assistants in nursing care:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gliesche et al. - 2018 - A qualitative survey on challenges and use-cases for robotic assistants in nursing care.pdf:pdf} }
  • [article] bibtex
    Myriam Lipprandt und Rainer Röhrig, "Sicherheitskritische Mensch-Maschine-Interaktion in der Medizin" Sicherheitskritische Mensch-Computer-Interaktion Wiesbaden : Springer Vieweg, 2018 (2018), Seite 297-315 xxvi, 645 Seiten, 2018.
    @article{MyriamLipprandt.2018,
      author = {{Myriam Lipprandt} and {Rainer R{\"o}hrig}},
      year = {2018},
      title = {Sicherheitskritische Mensch-Maschine-Interaktion in der Medizin},
      keywords = {inf 080},
      journal = {Sicherheitskritische Mensch-Computer-Interaktion Wiesbaden : Springer Vieweg, 2018 (2018), Seite 297-315 xxvi, 645 Seiten} }
  • [article] bibtex
    A. Bartsch, M. Härter, A. L. Brütt, und A. Buchholz, "Prozessevaluation einer Intervention zur kooperativen Raucherentwöhnung" Prävention und Gesundheitsförderung, 2018.
    @article{Bartsch.2018,
      author = {Bartsch, Anna-Lena and H{\"a}rter, Martin and Br{\"u}tt, Anna Levke and Buchholz, Angela},
      year = {2018},
      title = {Prozessevaluation einer Intervention zur kooperativen Raucherentw{\"o}hnung},
      issn = {1861-6763},
      journal = {Pr{\"a}vention und Gesundheitsf{\"o}rderung},
      doi = {10.1007/s11553-017-0635-9} }
  • [article] bibtex
    A. Gerka, S. Remy, C. Lins, C. Lüpkes, und A. Hein, "Analyse von Versorgungsprozessen in Wohngemeinschaften für Menschen mit eingeschränkter Alltagskompentenz" 17. Deutscher Kongress für Versorgungsforschung, 2018.
    @article{Gerka.2018,
      author = {Gerka, Alexander and Remy, Simon and Lins, Christian and L{\"u}pkes, Christian and Hein, Andreas},
      year = {2018},
      title = {Analyse von Versorgungsprozessen in Wohngemeinschaften f{\"u}r Menschen mit eingeschr{\"a}nkter Alltagskompentenz},
      journal = {17. Deutscher Kongress f{\"u}r Versorgungsforschung},
      doi = {10.3205/18dkvf116},
      file = {Gerka et al. - 2018 - Analyse von Versorgungsprozessen in Wohngemeinschaften für Menschen mit eingeschränkter Alltagskompentenz:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2018 - Analyse von Versorgungsprozessen in Wohngemeinschaften für Menschen mit eingeschränkter Alltagskompentenz.pdf:pdf} }
  • [article] bibtex
    A. Gerka, C. Lins, M. Lipprandt, und A. Hein, "Requirements for Ambient Sensors that Enhance the Safety of Artificially Ventilated Patients" Zukunft der Pflege Tagungsband der 1. Clusterkonferenz 2018 Innovative Technologien für die Pflege, 2018.
    @article{Gerka.2018c,
      author = {Gerka, Alexander and Lins, Christian and Lipprandt, Myriam and Hein, Andreas},
      year = {2018},
      title = {Requirements for Ambient Sensors that Enhance the Safety of Artificially Ventilated Patients},
      keywords = {ambient;andreas;artificial ventilation;carl von ossietzky university;hein;home mechanical ventilation;myriam lipprandt;requirements engineering;safety systems;sensors},
      journal = {Zukunft der Pflege Tagungsband der 1. Clusterkonferenz 2018 Innovative Technologien f{\"u}r die Pflege},
      file = {Gerka et al. - 2018 - Requirements for Ambient Sensors that Enhance the Safety of Artificially Ventilated Patients:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2018 - Requirements for Ambient Sensors that Enhance the Safety of Artificially Ventilated Patients.pdf:pdf} }
  • [incollection] bibtex
    S. Birkner, M. H. Freitag, und F. Koppelin, "Gendersensibilität als Innovationstreiber im Gesundheitswesen" in Entrepreneurship im Gesundheitswesen I, Springer, 2018, pp. 221-242.
    @incollection{Birkner.2018,
      author = {Birkner, Stephanie and Freitag, Michael H. and Koppelin, Frauke},
      title = {Gendersensibilit{\"a}t als Innovationstreiber im Gesundheitswesen},
      pages = {221--242},
      publisher = {Springer},
      booktitle = {Entrepreneurship im Gesundheitswesen I},
      year = {2018} }
  • [inproceedings] bibtex
    D. Eckhoff, C. Sandor, D. Kalkofen, U. Eck, C. Lins, und A. Hein, "TutAR: Semi-Automatic Generation of Augmented Reality Tutorials for Medical Education" in Proc. IEEE International Symposium on Mixed and Augmented Reality Adjunct (ISMAR-Adjunct), 2018.
    @inproceedings{Eckhoff.2018b,
      author = {Eckhoff, Daniel and Sandor, Christian and Kalkofen, Denis and Eck, Ulrich and Lins, Christian and Hein, Andreas},
      title = {TutAR: Semi-Automatic Generation of Augmented Reality Tutorials for Medical Education},
      booktitle = {IEEE International Symposium on Mixed and Augmented Reality Adjunct (ISMAR-Adjunct)},
      year = {2018},
      doi = {10.1109/ISMAR-Adjunct.2018.00131},
      file = {Eckhoff et al. - 2018 - TutAR Semi-Automatic Generation of Augmented Reality Tutorials for Medical Education:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Eckhoff et al. - 2018 - TutAR Semi-Automatic Generation of Augmented Reality Tutorials for Medical Education.pdf:pdf} }
  • [book] bibtex
    Organizational Behaviour in Healthcare: Theoretical Approaches, Methods and Empirical Results, 1 ed., Körner, M., Ansmann, L., Schwarz, B., und Kowalski, C., Eds., Wien, Österreich: , 2018, vol. 28.
    @book{Korner.2018b, year = {2018},
      title = {Organizational Behaviour in Healthcare: Theoretical Approaches, Methods and Empirical Results},
      address = {Wien, {\"O}sterreich},
      edition = {1},
      volume = {28},
      series = {Medizinsoziologie},
      editor = {K{\"o}rner, M. and Ansmann, Lena and Schwarz, B. and Kowalski, Christoph} }
  • [inproceedings] bibtex
    D. Eckhoff, C. Sandor, C. Lins, U. Eck, D. Kalkofen, und A. Hein, "TutAR: augmented reality tutorials for hands-only procedures" in Proc. Proceedings of the 16th ACM SIGGRAPH International Conference on Virtual-Reality Continuum and its Applications in Industry - VRCAI '18, 2018.
    @inproceedings{Eckhoff.2018,
      author = {Eckhoff, Daniel and Sandor, Christian and Lins, Christian and Eck, Ulrich and Kalkofen, Denis and Hein, Andreas},
      title = {TutAR: augmented reality tutorials for hands-only procedures},
      isbn = {9781450360876},
      booktitle = {Proceedings of the 16th ACM SIGGRAPH International Conference on Virtual-Reality Continuum and its Applications in Industry - VRCAI '18},
      year = {2018},
      doi = {10.1145/3284398.3284399},
      file = {Eckhoff et al. - 2018 - TutAR augmented reality tutorials for hands-only procedures:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Eckhoff et al. - 2018 - TutAR augmented reality tutorials for hands-only procedures.pdf:pdf} }
  • [article] bibtex
    C. Lins, S. Fudickar, und A. Hein, "XML Skeleton Definitions for Human Posture Assessments" Studies in Health Technology and Informatics, 2018.
    @article{Lins.2018e, abstract = {In this paper, we show how the XML dialect SKAML (Skeletal Assessment Markup Language) can be used to use data from one or more Motion Capture systems to perform human posture assessments with multiple assessment methods. We show an implementation example using an inertial measuring suit and both OWAS and REBA assessment methods. SKAML makes it possible to implement classifiers for a Motion Capture system once and adapt the classifier by-configuration to various ergonomics assessment methods. We anticipate our work as help for researchers and developers that implement new assessment methods or motion capture systems.},
      author = {Lins, Christian and Fudickar, Sebastian and Hein, Andreas},
      year = {2018},
      title = {XML Skeleton Definitions for Human Posture Assessments},
      keywords = {Motion Capture;Musculoskeletal Disorders;OWAS;Posture Assessment;Posture Classification;REBA;SKAML;Skeleton Markup;UNIAMT;Unpublished},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      file = {Lins, Fudickar, Hein - 2018 - XML Skeleton Definitions for Human Posture Assessments:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins, Fudickar, Hein - 2018 - XML Skeleton Definitions for Human Posture Assessments.pdf:pdf} }
  • [article] bibtex
    N. Volkening, J. W. Rieger, S. Fudickar, und A. Hein, "Development of a Mobile Functional Near-infrared Spectroscopy Prototype and its Initial Evaluation via Motor Cortical Activities - Lessons Learned" PETRA'18, 2018.
    @article{Volkening.2018c, abstract = {This paper presents a new mobile near-infrared functional spectroscopy (fNIRS) device, with digital detectors that can be placed anywhere on the head and fit into standard caps to measure cortical brain activation. The device's functionality was evaluated in two steps, i.e. first, by means of simple pulse measurements and second, in a motor cortex study with nine subjects. In this study, the subjects had to alternate between right and left hands while using hand-held strength trainers. While the signals from the mobile prototype were not yet stable enough across all channels to perform analysis such as statistical parametric mapping, it was able to measure significant brain activation changes over the area of the motor cortex with the mobile prototype when the contralateral hand was activated in four subjects. In contrast, the device was yet unable to measure ipsilateral activities. The problems encountered and possible methods to improve signal acquisition are discussed at the end of the paper.},
      author = {Volkening, Nils and Rieger, Jochem W. and Fudickar, Sebastian and Hein, Andreas},
      year = {2018},
      title = {Development of a Mobile Functional Near-infrared Spectroscopy Prototype and its Initial Evaluation via Motor Cortical Activities - Lessons Learned},
      keywords = {accepted;AMTCSE;AMTUNI;fnirs;full paper;functional near-infrared spectroscopy;is a non-invasive;is used;method for the imaging;mobile fnirs;motor cortical activity;of the central nervous;prototype;system},
      journal = {PETRA'18},
      doi = {10.1145/3197768.3201534},
      file = {Volkening et al. - 2018 - Development of a Mobile Functional Near-infrared Spectroscopy Prototype and its Initial Evaluation via Motor C:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Volkening et al. - 2018 - Development of a Mobile Functional Near-infrared Spectroscopy Prototype and its Initial Evaluation via Motor C.pdf:pdf} }
  • P. von Gablenz, F. Otto-Sobotka, und I. Holube, "Adjusting Expectations: Hearing Abilities in a Population-Based Sample Using an SSQ Short Form" Trends Hear, vol. 22, p. 2331216518784837, 2018.
    @article{vonGablenz.2018,
      author = {{von Gablenz},
      P. and Otto-Sobotka, F. and Holube, I.},
      year = {2018},
      title = {Adjusting Expectations: Hearing Abilities in a Population-Based Sample Using an SSQ Short Form},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/30022731 https://journals.sagepub.com/doi/pdf/10.1177/2331216518784837},
      pages = {2331216518784837},
      volume = {22},
      journal = {Trends Hear},
      doi = {10.1177/2331216518784837} }
  • [incollection] bibtex
    L. Ansmann, C. Kowalski, und H. Paff, "Work Organization in Breast Cancer Centres: Do Hospitals Structures Account for Differences?" in Organizational Behaviour in Healthcare, Körner, M., Ansmann, L., Schwarz, B., und Kowalski, C., Eds., Wien, Österreich: , 2018, pp. 107-134.
    @incollection{Ansmann.2018c,
      author = {Ansmann, Lena and Kowalski, Christoph and Paff, Holger},
      title = {Work Organization in Breast Cancer Centres: Do Hospitals Structures Account for Differences?},
      pages = {107--134},
      series = {Medizinsoziologie},
      editor = {K{\"o}rner, M. and Ansmann, Lena and Schwarz, B. and Kowalski, Christoph},
      booktitle = {Organizational Behaviour in Healthcare},
      year = {2018},
      address = {Wien, {\"O}sterreich} }
  • [incollection] bibtex
    N. Ernstmann, S. E. Groß, L. Ansmann, A. Nitzsche, C. Heuser, W. Baumann, M. A. Wirtz, H. Pfaff, und M. Neumann, "Interruptions and Patient-Physician-Communication: an Exploratory Mixed Methods Study in Oncology Practices" in Organizational Behaviour in Healthcare, Körner, M., Ansmann, L., Schwarz, B., und Kowalski, C., Eds., Wien, Österreich: , 2018, pp. 209-238.
    @incollection{Ernstmann.2018,
      author = {Ernstmann, Nicole and Gro{\ss},
      Sophie Elisabeth and Ansmann, Lena and Nitzsche, A. and Heuser, Christian and Baumann, Walter and Wirtz, Markus Antonius and Pfaff, H. and Neumann, M.},
      title = {Interruptions and Patient-Physician-Communication: an Exploratory Mixed Methods Study in Oncology Practices},
      pages = {209--238},
      series = {Medizinsoziologie},
      editor = {K{\"o}rner, M. and Ansmann, Lena and Schwarz, B. and Kowalski, Christoph},
      booktitle = {Organizational Behaviour in Healthcare},
      year = {2018},
      address = {Wien, {\"O}sterreich} }
  • [incollection] bibtex
    M. Körner, L. Luzay, L. Ansmann, B. Schwarz, und C. Kowalski, "Introduction to Organizational Behaviour in Healthcare" in Organizational Behaviour in Healthcare, Körner, M., Ansmann, L., Schwarz, B., und Kowalski, C., Eds., Wien, Österreich: , 2018, pp. 19-32.
    @incollection{Korner.2018,
      author = {K{\"o}rner, M. and Luzay, L. and Ansmann, Lena and Schwarz, B. and Kowalski, Christoph},
      title = {Introduction to Organizational Behaviour in Healthcare},
      pages = {19--32},
      series = {Medizinsoziologie},
      editor = {K{\"o}rner, M. and Ansmann, Lena and Schwarz, B. and Kowalski, Christoph},
      booktitle = {Organizational Behaviour in Healthcare},
      year = {2018},
      address = {Wien, {\"O}sterreich} }
  • [incollection] bibtex
    C. Kowalski, L. Ansmann, B. Schwarz, und M. Körner, "Organizational Behaviour in Healthcare: Where to Go from Here?" in Organizational Behaviour in Healthcare, Körner, M., Ansmann, L., Schwarz, B., und Kowalski, C., Eds., Wien, Österreich: , 2018, pp. 381-389.
    @incollection{Kowalski.2018,
      author = {Kowalski, Christoph and Ansmann, Lena and Schwarz, B. and K{\"o}rner, M.},
      title = {Organizational Behaviour in Healthcare: Where to Go from Here?},
      pages = {381--389},
      series = {Medizinsoziologie},
      editor = {K{\"o}rner, M. and Ansmann, Lena and Schwarz, B. and Kowalski, Christoph},
      booktitle = {Organizational Behaviour in Healthcare},
      year = {2018},
      address = {Wien, {\"O}sterreich} }
  • [incollection] bibtex
    N. Scholten, L. Ansmann, und H. Pfaff, "Associations Between Organizational Characteristics and Physician Well-Being and Their Relevance to Quality of Care: a Study in German Breast Cancer Centre Hospitals" in Organizational Behaviour in Healthcare, Körner, M., Ansmann, L., Schwarz, B., und Kowalski, C., Eds., Wien, Österreich: , 2018, pp. 135-162.
    @incollection{Scholten.2018,
      author = {Scholten, Nadine and Ansmann, Lena and Pfaff, H.},
      title = {Associations Between Organizational Characteristics and Physician Well-Being and Their Relevance to Quality of Care: a Study in German Breast Cancer Centre Hospitals},
      pages = {135--162},
      series = {Medizinsoziologie},
      editor = {K{\"o}rner, M. and Ansmann, Lena and Schwarz, B. and Kowalski, Christoph},
      booktitle = {Organizational Behaviour in Healthcare},
      year = {2018},
      address = {Wien, {\"O}sterreich} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    P. Elfert, J. Wojzischke, M. Eichelberg, und A. Hein, "Ein ambientes System zur Erfassung und Digitalisierung von Gesundheitsparameters mit dem Ziel, Ernährungsberatung für anfällige Patienten zu ermöglichen" in Proc. Tagungsband Wissenschaftskongress Active Assisted Living, Karlsruhe, 2018, p. 72.
    @inproceedings{Elfert.2018,
      author = {Elfert, Patrick and Wojzischke, Julia and Eichelberg, Marco and Hein, Andreas},
      title = {Ein ambientes System zur Erfassung und Digitalisierung von Gesundheitsparameters mit dem Ziel, Ern{\"a}hrungsberatung f{\"u}r anf{\"a}llige Patienten zu erm{\"o}glichen},
      url = {https://www.aal-karlsruhe.com/data/downloads/aal_2018_tagungsband_web.pdf},
      pages = {72},
      booktitle = {Tagungsband Wissenschaftskongress Active Assisted Living},
      year = {2018},
      address = {Karlsruhe},
      file = {Elfert et al. - 2018 - Ein ambientes System zur Erfassung und Digitalisierung von Gesundheitsparameters mit dem Ziel, Ernährungsberatung:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Elfert et al. - 2018 - Ein ambientes System zur Erfassung und Digitalisierung von Gesundheitsparameters mit dem Ziel, Ernährungsberatung.pdf:pdf} }
  • [inproceedings] bibtex
    C. Lins, S. Fudickar, und A. Hein, "SKAML: An XML Markup Language for Abstract Skeleton Definitions in the Context of Human Posture Assessments" in Proc. Medical Informatics Europe, Gothenburg, Sweden, 2018.
    @inproceedings{Lins.2018f, abstract = {An XML-dialect for the description and configuration of abstract human skeletons for ergonomics assessments with motion capture (MoCap) systems -the Skeletal Assessment Markup Language (SKAML) -is presented. A SKAML document is the semantic description of the MoCap system and assessment method conjunction. It describes the skeletal system of a human body as a system of rigid bones and joints from a MoCap observer perspective and allows straightforward combinations of MoCap data and digitized methods for ergonomics assessments. We anticipate our work as help for researchers and developers that implement new assessment methods or MoCap systems.},
      author = {Lins, Christian and Fudickar, Sebastian and Hein, Andreas},
      title = {SKAML: An XML Markup Language for Abstract Skeleton Definitions in the Context of Human Posture Assessments},
      keywords = {Ergonomics Assessment;Informationenfehlen;Motion Capture;Musculoskeletal Disorders;Skeleton Markup;UNIAMT;UNILLM;Unpublished},
      booktitle = {Medical Informatics Europe},
      year = {2018},
      address = {Gothenburg, Sweden},
      file = {Lins, Fudickar, Hein - 2018 - SKAML An XML Markup Language for Abstract Skeleton Definitions in the Context of Human Posture Assessments:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins, Fudickar, Hein - 2018 - SKAML An XML Markup Language for Abstract Skeleton Definitions in the Context of Human Posture Assessments.pdf:pdf} }
  • [inproceedings] bibtex
    C. Lins, S. Fudickar, A. Gerka, und A. Hein, "A Wearable Vibrotactile Interface for Unfavorable Posture Awareness Warning" in Proc. Medical Informatics Europe, Gothenburg, Sweden, 2018.
    @inproceedings{Lins.2018g, abstract = {We present the concept of a vibrotactile interface with up to 13 tactors (vibration motors) that are distributed over the full body to warn industry workers when taking unfavorable postures. The developed system is to be integrated into a motion capture workwear for industry workers to serve as posture feedback system to prevent unfavorable or even harmful postures. Such postures are a risk factor for musculoskeletal disorders (MSD), especially among older adults. We evaluated the vibrotactile system with 11 subjects to identify the optimal notification vibration sequences (regarding pulse length and repetition) and the accuracy of the location-dependent perception. Results indicate that the optimal pulse length is about 150 ms and is repeated 2 or 3 times within the sequence for maximum attention.},
      author = {Lins, Christian and Fudickar, Sebastian and Gerka, Alexander and Hein, Andreas},
      title = {A Wearable Vibrotactile Interface for Unfavorable Posture Awareness Warning},
      keywords = {Ergonomics Feedback;Haptics;Informationenfehlen;Occupational Ergonomics;Posture Warning;UNIAMT;UNILLM;Unpublished;Vibrotactile Interface;Wearables},
      booktitle = {Medical Informatics Europe},
      year = {2018},
      address = {Gothenburg, Sweden},
      file = {Lins et al. - 2018 - A Wearable Vibrotactile Interface for Unfavorable Posture Awareness Warning:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins et al. - 2018 - A Wearable Vibrotactile Interface for Unfavorable Posture Awareness Warning.pdf:pdf} }
  • [article] bibtex
    A. Bartsch, L. M. Carlsen, M. Härter, A. L. Brütt, und A. Buchholz, "A cross-sectional survey of factors associated with the uptake of smoking cessation aids among smokers and ex-smokers" Journal of Substance Use, vol. 23, iss. 6, pp. 1-6, 2018.
    @article{Bartsch.2018b,
      author = {Bartsch, Anna-Lena and Carlsen, Lina Marie and H{\"a}rter, Martin and Br{\"u}tt, Anna Levke and Buchholz, Angela},
      year = {2018},
      title = {A cross-sectional survey of factors associated with the uptake of smoking cessation aids among smokers and ex-smokers},
      pages = {1--6},
      volume = {23},
      number = {6},
      issn = {1465-9891},
      journal = {Journal of Substance Use},
      doi = {10.1080/14659891.2018.1459906} }
  • [article] bibtex
    C. Heuser, A. Diekmann, L. Ansmann, und N. Ernstmann, "Patientinnenteilnahme an Tumorkonferenzen: ein wichtiger Faktor für eine gemeinsame Entscheidungsfindung?" Deutsche Zeitschrift für Onkologie, vol. 50, iss. 02, pp. 56-59, 2018.
    @article{Heuser.2018,
      author = {Heuser, Christian and Diekmann, Annika and Ansmann, Lena and Ernstmann, Nicole},
      year = {2018},
      title = {Patientinnenteilnahme an Tumorkonferenzen: ein wichtiger Faktor f{\"u}r eine gemeinsame Entscheidungsfindung?},
      pages = {56--59},
      volume = {50},
      number = {02},
      issn = {1617-5891},
      journal = {Deutsche Zeitschrift f{\"u}r Onkologie},
      doi = {10.1055/a-0589-7499} }
  • [article] bibtex
    U. Karbach, L. Ansmann, N. Scholten, H. Pfaff, C. Albus, F. Jessen, L. Kuntz, C. Rietz, I. Schubert, F. Schulz-Nieswandt, S. Stock, J. Strupp, und R. Voltz, "Bericht aus einem laufenden Forschungsprojekt: CoRe-Net, das Kölner Kompetenznetzwerk aus Versorgungspraxis und Versorgungsforschung, und der Value-based Healthcare-Ansatz" Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, vol. 130, pp. 21-26, 2018.
    @article{Karbach.2018, abstract = {With the BMBF's funding program {\textquotedbl}Structural Development in Health Services Research{\textquotedbl} the Cologne Research and Development Network CoRe-Net is being set up by various partners from both clinical practice and health services research. The network focuses on the further development of healthcare according to the concept of learning organizations. On the basis of three research projects, the Cologne network CoRe-Net aims to establish itself in a sustainable manner and analyze healthcare delivery for two vulnerable patient groups. The two groups include a) deceased patients in Cologne and b) people suffering from heart disease and an associated mental comorbidity. The Cologne network CoRe-Net is based on M.E. Porter's value-based healthcare approach.},
      author = {Karbach, Ute and Ansmann, Lena and Scholten, Nadine and Pfaff, Holger and Albus, Christian and Jessen, Frank and Kuntz, Ludwig and Rietz, Christian and Schubert, Ingrid and Schulz-Nieswandt, Frank and Stock, Stephanie and Strupp, Julia and Voltz, Raymond},
      year = {2018},
      title = {Bericht aus einem laufenden Forschungsprojekt: CoRe-Net, das K{\"o}lner Kompetenznetzwerk aus Versorgungspraxis und Versorgungsforschung, und der Value-based Healthcare-Ansatz},
      pages = {21--26},
      volume = {130},
      journal = {Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen},
      doi = {10.1016/j.zefq.2017.11.005},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29269171} }
  • [article] bibtex
    C. Lins, A. Gerka, C. Lüpkes, R. Röhrig, und A. Hein, "Enhancing Safety of Artificially Ventilated Patients Using Ambient Process Analysis" Studies in Health Technology and Informatics, vol. 247, pp. 316-320, 2018.
    @article{Lins.2018c, abstract = {In this paper, we present an approach for enhancing the safety of artificially ventilated patients using ambient process analysis. We propose to use an analysis system consisting of low-cost ambient sensors such as power sensor, RGB-D sensor, passage detector, and matrix infrared temperature sensor to reduce risks for artificially ventilated patients in both home and clinical environments. We describe the system concept and our implementation and show how the system can contribute to patient safety.},
      author = {Lins, Christian and Gerka, Alexander and L{\"u}pkes, Christian and R{\"o}hrig, Rainer and Hein, Andreas},
      year = {2018},
      title = {Enhancing Safety of Artificially Ventilated Patients Using Ambient Process Analysis},
      pages = {316--320},
      volume = {247},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29677974} }
  • T. Probst, M. Dehoust, A. L. Brütt, H. Schulz, C. Pieh, und S. Andreas, "Mentalization and Self-Efficacy as Mediators between Psychological Symptom Severity and Disabilities in Activities and Participation in Psychotherapy Patients" Psychopathology, vol. 51, iss. 1, pp. 38-46, 2018.
    @article{Probst.2018,
      author = {Probst, T. and Dehoust, M. and Br{\"u}tt, Anna Levke and Schulz, H. and Pieh, C. and Andreas, S.},
      year = {2018},
      title = {Mentalization and Self-Efficacy as Mediators between Psychological Symptom Severity and Disabilities in Activities and Participation in Psychotherapy Patients},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/29346789},
      pages = {38--46},
      volume = {51},
      number = {1},
      journal = {Psychopathology},
      doi = {10.1159/000485980} }
  • T. Reinders, J. Kieschke, A. Timmer, und V. Jürgens, "Sequential tests for monitoring methods to detect elevated incidence - a simulation study" BMC cancer, vol. 18, iss. 1, p. 384, 2018.
    @article{Reinders.2018,
      author = {Reinders, Tammo and Kieschke, Joachim and Timmer, Antje and J{\"u}rgens, Verena},
      year = {2018},
      title = {Sequential tests for monitoring methods to detect elevated incidence - a simulation study},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/29618322 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885463/pdf/12885_2018_Article_4259.pdf},
      pages = {384},
      volume = {18},
      number = {1},
      journal = {BMC cancer},
      doi = {10.1186/s12885-018-4259-z} }
  • [article] bibtex
    N. Reiss, F. Müller-von-Aschwege, T. Schmidt, C. Feldmann, J. D. Schmitto, A. Hein, und J. I. Glitza, "Development of New Algorithms for Early Detection of Pump Thrombosis by Analysis of HeartWare LVAD Log Files" Journal of Heart and Lung Transplantation, vol. 37, iss. 4, 2018.
    @article{Reiss.2018,
      author = {Reiss, Nils and M{\"u}ller-von-Aschwege, Frerk and Schmidt, Thomas and Feldmann, Christina and Schmitto, Jan Dieter and Hein, Andreas and Glitza, Jenny Inge},
      year = {2018},
      title = {Development of New Algorithms for Early Detection of Pump Thrombosis by Analysis of HeartWare LVAD Log Files},
      volume = {37},
      number = {4},
      issn = {1053-2498},
      journal = {Journal of Heart and Lung Transplantation},
      doi = {10.1016/j.healun.2018.01.007{\%}0A},
      file = {Reiss et al. - 2018 - Development of New Algorithms for Early Detection of Pump Thrombosis by Analysis of HeartWare LVAD Log Files:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Reiss et al. - 2018 - Development of New Algorithms for Early Detection of Pump Thrombosis by Analysis of HeartWare LVAD Log Files.pdf:pdf} }
  • N. Rimon-Zarfaty und M. Schweda, "Biological clocks, biographical schedules and generational cycles. Temporality in the ethics of assisted reproduction" Bioethica Forum, vol. 11, iss. 4, pp. 133-141, 2018.
    @article{RimonZarfaty.2018,
      author = {Rimon-Zarfaty, Nitzan and Schweda, Mark},
      year = {2018},
      title = {Biological clocks, biographical schedules and generational cycles. Temporality in the ethics of assisted reproduction},
      url = {http://www.bioethica-forum.ch/content/d_AktAusgabe.php},
      pages = {133--141},
      volume = {11},
      number = {4},
      issn = {1662-601X},
      journal = {Bioethica Forum} }
  • A. Timmer, D. de Sordi, E. Menke, J. Peplies, M. Classen, S. Koletzko, und F. Otto-Sobotka, "Modeling determinants of satisfaction with health care in youth with inflammatory bowel disease: a cross-sectional survey" Clinical Epidemiology, vol. 10, pp. 1289-1305, 2018.
    @article{Timmer.2018,
      author = {Timmer, Antje and {de Sordi},
      D. and Menke, E. and Peplies, Jenny and Classen, M. and Koletzko, Sibylle and Otto-Sobotka, F.},
      year = {2018},
      title = {Modeling determinants of satisfaction with health care in youth with inflammatory bowel disease: a cross-sectional survey},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/30310323 https://www.dovepress.com/front_end/cr_data/cache/pdf/download_1605018337_5faaa2e15859d/clep-165554-modeling-determinants-of-satisfaction-with-health-care-in-yo-092418.pdf},
      pages = {1289--1305},
      volume = {10},
      issn = {1179-1349 (Print) 1179-1349},
      journal = {Clinical Epidemiology},
      doi = {10.2147/CLEP.S165554} }
  • [article] bibtex
    A. Zeleke, T. P. Naziyok, M. Wilken, und R. Röhrig, "An Online Differential Cost Estimator Tool to Support Cost Planning of Demographic and Health Surveys Using Mobile Electronic Device or Paper and Pen Methods: A Function of Sample Size" Studies in Health Technology and Informatics, vol. 253, pp. 11-15, 2018.
    @article{Zeleke.2018, abstract = {The use of mobile devices for a house to house interview-administered survey data collection is becoming a practice along with the paper-based data collection tools. Though the electronic data capture mechanism is supposed to improve the efficiency of the data collection mechanism and the quality of the data, there is limited evidence on the cost-effectiveness of the technologies. This project aims to develop an online pre-implementation survey cost estimator to support the planning and decision of implementing agency. Scalable costs with sample size were estimated using parametric cost estimating technique. In this article, we used Introduction, State of the art, Concept, Implementation, Lessons Learned (ISCIL) format to present the overall development process of this online cost estimator.},
      author = {Zeleke, Atinkut and Naziyok, Tolga P. and Wilken, Marc and R{\"o}hrig, Rainer},
      year = {2018},
      title = {An Online Differential Cost Estimator Tool to Support Cost Planning of Demographic and Health Surveys Using Mobile Electronic Device or Paper and Pen Methods: A Function of Sample Size},
      pages = {11--15},
      volume = {253},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30147030} }
  • [inproceedings] bibtex
    N. Volkening, A. Unni, J. W. Rieger, S. Fudickar, und A. Hein, "Development of a mobile Functional Near-infrared Spectroscopy prototype" in Proc. Internet of Vehicles. Technologies and Services Towards Smart City, 2018, p. p 1-16.
    @inproceedings{Volkening.2018, abstract = {Driving is a complex and cognitively demanding task. It is important to assess the cognitive state of the driver in order to develop cognitive technical systems that can adapt to different cognitive states of the driver. For this purpose, we have de-veloped a mobile functional near-infrared spectroscopy (mofNIRS) prototype. This paper describes the improvements of this mobile prototype with freely placeable optodes on a subject's head and the results of an evaluation study. We conducted a motor cortex experiment with four subjects, whereby the mobile pro-totype was mounted on the right hemisphere and a commercial, stationary fNIRS on the left hemisphere above the motor cortex area. One data set had to be dis-carded due to incorrect synchronization between both systems. The results of the remaining three subjects are presented and discussed in this paper. Here, we re-port the results from the time-series and Statistical Parametric Mapping (SPM) analyses, which shows t-values with high differentiability of the Results. Fur-thermore, both analysis methods show comparable results between the commer-cial system and the mobile prototype.},
      author = {Volkening, Nils and Unni, Anirudh and Rieger, Jochem W. and Fudickar, Sebastian and Hein, Andreas},
      title = {Development of a mobile Functional Near-infrared Spectroscopy prototype},
      keywords = {accepted;full paper;OFFIS=G-AIT/AHT/CSE;UNIAMT;UNICSE},
      pages = {p 1--16},
      booktitle = {Internet of Vehicles. Technologies and Services Towards Smart City},
      year = {2018},
      doi = {10.1007/978-3-030-05081-8{\textunderscore }11},
      file = {Volkening et al. - 2018 - Development of a mobile Functional Near-infrared Spectroscopy prototype:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Volkening et al. - 2018 - Development of a mobile Functional Near-infrared Spectroscopy prototype.pdf:pdf} }
  • [article] bibtex
    K. Allers, F. Hoffmann, T. Mathes, und D. Pieper, "Systematic reviews with published protocols compared to those without: more effort, older search" Journal of Clinical Epidemiology, vol. 95, pp. 102-110, 2018.
    @article{Allers.2018, abstract = {OBJECTIVE: To explore trends in published protocols of systematic reviews (SRs) and to analyze how SRs with published protocols differ from those without. STUDY DESIGN AND SETTING: We searched PubMed up to December 31, 2016 to identify SR protocols. We also searched for the corresponding SR for each protocol published in 2012 and 2013 and matched this with an SR without published protocol by year and journal. RESULTS: The number of protocols published increased from 42 in 2012 to 404 in 2016; 125 were published in 2012 and 2013. One-third of SRs remained unpublished after 3-5~years. We included 80 SRs with protocols and 80 controls. SRs with protocols reported their methods more comprehensively than their controls, but their median time from search to submission was longer (325 vs. 122~days; P~{\textless}~0.001). Almost two-thirds of the SRs with protocols and about 10{\%} of the controls could be found in the International Prospective Register of Systematic Reviews (PROSPERO). CONCLUSION: Time from search to submission was longer for SRs with published protocols, while at the same time SRs with published protocols were better elaborated and reported. As quality, transparency, and currency are cornerstones of SRs, we suggest critically discussing the current practice of publishing SR protocols.},
      author = {Allers, Katharina and Hoffmann, Falk and Mathes, T. and Pieper, Dawid},
      year = {2018},
      title = {Systematic reviews with published protocols compared to those without: more effort, older search},
      keywords = {*Epidemiologic Methods;*Methodology;*prisma;*prospero;*Protocol;*Research reporting;*Systematic review;*Systematic Reviews as Topic;Humans;Periodicals as Topic/trends},
      pages = {102--110},
      volume = {95},
      issn = {0895-4356},
      journal = {Journal of Clinical Epidemiology},
      doi = {10.1016/j.jclinepi.2017.12.005} }
  • [article] bibtex
    L. Ansmann, N. Winter, N. Ernstmann, A. Heidenreich, L. Weissbach, und J. Herden, "Health-related quality of life in active surveillance and radical prostatectomy for low-risk prostate cancer: a prospective observational study (HAROW - Hormonal therapy, Active Surveillance, Radiation, Operation, Watchful Waiting)" BJU international, vol. 122, iss. 3, pp. 401-410, 2018.
    @article{Ansmann.2018, abstract = {OBJECTIVES To compare health-related quality of life (HRQOL) between patients with localised prostate cancer in an active surveillance (AS) group and a radical prostatectomy (RP) group, as evidence shows that both groups have similar oncological outcomes. Thus, comparative findings on the patients' HRQOL are becoming even more important to allow for informed treatment decision-making. PATIENTS AND METHODS The Hormonal therapy, Active Surveillance, Radiation, Operation, Watchful Waiting (HAROW) study is a prospective, observational study designed to collect data for different treatment options for newly diagnosed patients with localised prostate cancer under real-life conditions. At 6-month intervals, clinical data (D'Amico risk categories, Charlson Comorbidity Index) and HRQOL (European Organisation for Research and Treatment of Cancer quality of life questionnaire 30-item core questionnaire) were collected. Data were analysed by longitudinal multilevel analysis for patients with localised prostate cancer under AS and RP. RESULTS Data from 961 patients (556 RP, 405 AS) were considered. The follow-up was 3.5 years (median 2 years). The results reveal significant, but not clinically relevant advantages for patients with low-risk prostate cancer managed with AS in contrast to RP concerning global HRQOL as well as role, emotional and social functioning over time, after controlling for age, comorbidities, and partnership status. In some, but not all HRQOL scales, RP patients start with a slightly lower HRQOL and recover up to the level of AS patients within 1-2 years after diagnosis. CONCLUSION HRQOL is an important aspect in the decision-making and advising process for patients with prostate cancer. In many aspects of HRQOL, AS is associated with more favourable outcomes than RP within the first 1-2 years after diagnosis in our observational design, although the differences were not clinically significant. The result that HRQOL in AS patients is at least as high as in RP patients should be considered when advising patients about the different treatment options for low-risk localised prostate cancer.},
      author = {Ansmann, Lena and Winter, Nicola and Ernstmann, Nicole and Heidenreich, Axel and Weissbach, Lothar and Herden, Jan},
      year = {2018},
      title = {Health-related quality of life in active surveillance and radical prostatectomy for low-risk prostate cancer: a prospective observational study (HAROW - Hormonal therapy, Active Surveillance, Radiation, Operation, Watchful Waiting)},
      pages = {401--410},
      volume = {122},
      number = {3},
      journal = {BJU international},
      doi = {10.1111/bju.14215},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29603553} }
  • [article] bibtex
    L. Ansmann und H. Pfaff, "Providers and Patients Caught Between Standardization and Individualization: Individualized Standardization as a Solution Comment on \textquotedbl(Re) Making the Procrustean Bed? Standardization and Customization as Competing Logics in Healthcare\textquotedbl" International journal of health policy and management, vol. 7, iss. 4, pp. 349-352, 2018.
    @article{Ansmann.2018b, abstract = {In their 2017 article, Mannion and Exworthy provide a thoughtful and theory-based analysis of two parallel trends in modern healthcare systems and their competing and conflicting logics: standardization and customization. This commentary further discusses the challenge of treatment decision-making in times of evidence-based medicine (EBM), shared decision-making and personalized medicine. From the perspective of systems theory, we propose the concept of individualized standardization as a solution to the problem. According to this concept, standardization is conceptualized as a guiding framework leaving room for individualization in the patient physician interaction. The theoretical background is the concept of context management according to systems theory. Moreover, the comment suggests multidisciplinary teams as a possible solution for the integration of standardization and individualization, using the example of multidisciplinary tumor conferences and highlighting its limitations. The comment also supports the authors' statement of the patient as co-producer and introduces the idea that the competing logics of standardization and individualization are a matter of perspective on macro, meso and micro levels.},
      author = {Ansmann, Lena and Pfaff, Holger},
      year = {2018},
      title = {Providers and Patients Caught Between Standardization and Individualization: Individualized Standardization as a Solution Comment on {\textquotedbl}(Re) Making the Procrustean Bed? Standardization and Customization as Competing Logics in Healthcare{\textquotedbl}},
      pages = {349--352},
      volume = {7},
      number = {4},
      journal = {International journal of health policy and management},
      doi = {10.15171/ijhpm.2017.95},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29626403},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949226} }
  • [article] bibtex
    L. Ansmann, H. A. Hillen, L. Kuntz, S. Stock, V. Vennedey, und K. Hower, "Characteristics of value-based health and social care from organisations' perspectives (OrgValue): a mixed-methods study protocol" BMJ open, vol. 8, iss. 4, p. 022635, 2018.
    @article{Ansmann.2018d, abstract = {INTRODUCTION Health and social care systems are under pressure to organise care around patients' needs with constrained resources. Several studies reveal that care is constantly challenged by balancing economic requirements against individual patients' preferences and needs. Therefore, value-based health and social care aims to facilitate patient-centredness while taking the resources spent into consideration. The OrgValue project examines the implementation of patient-centredness while considering the health and social care organisations' resource orientation in the model region of the city of Cologne, Germany. METHODS AND ANALYSIS First, the implementation status of patient-centredness as well as its facilitators and barriers-also in terms of resource orientation-will be assessed through face-to-face interviews with decision-makers (at least n=18) from health and social care organisations (HSCOs) in Cologne. Second, patients' understanding of patient-centredness and their preferences and needs will be revealed by conducting face-to-face interviews (at least n=15). Third, the qualitative results will provide the basis for a quantitative survey of decision-makers from all HSCOs in Cologne, which will include questions on patient-centredness, resource orientation and determinants of implementation. Fourth, qualitative interviews with decision-makers from different types of HSCOs will be conducted to develop a uniform measurement instrument on the cost and service structure of HSCOs. ETHICS AND DISSEMINATION For all collected data, the relevant data protection regulations will be adhered to. Consultation and a positive vote from the ethics committee of the Medical Faculty of the University of Cologne have been obtained. All personal identifiers (eg, name, date of birth) will be pseudonymised. Dissemination strategies include a feedback report as well as research and development workshops for the organisations with the aim of initiating organisational learning and organisational development, presenting results in publications and at conferences, and public relations. TRIAL REGISTRATION NUMBER DRKS00011925.},
      author = {Ansmann, Lena and Hillen, Hendrik Ansgar and Kuntz, Ludwig and Stock, Stephanie and Vennedey, Vera and Hower, Kira},
      year = {2018},
      title = {Characteristics of value-based health and social care from organisations' perspectives (OrgValue): a mixed-methods study protocol},
      pages = {e022635},
      volume = {8},
      number = {4},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2018-022635},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922512},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29703859} }
  • T. Bernges, L. Iden, R. Gielen, M. Scholl, und A. L. Brütt, "Forschen für uns! Welche Forschungsthemen interessieren von Depression Betroffene?" Psychiatr Prax, vol. 45, iss. 7, pp. 383-386, 2018.
    @article{Bernges.2018,
      author = {Bernges, T. and Iden, L. and Gielen, R. and Scholl, M. and Br{\"u}tt, Anna Levke},
      year = {2018},
      title = {Forschen f{\"u}r uns! Welche Forschungsthemen interessieren von Depression Betroffene?},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/28850999},
      pages = {383--386},
      volume = {45},
      number = {7},
      issn = {0303-4259},
      journal = {Psychiatr Prax},
      doi = {10.1055/s-0043-118147} }
  • [article] bibtex
    B. Engel, S. Schacher, K. Weckbecker, A. Stausberg, und I. Gräff, "Der akute Gichtanfall in der zentralen Notaufnahme" Zeitschrift fur Orthopadie und Unfallchirurgie, vol. 156, iss. 6, pp. 653-661, 2018.
    @article{Engel.2018, abstract = {BACKGROUND Gout or hyperuricemia are both well known and common diseases. The prevalence of gout is increasing worldwide. Thus, patients with gout are becoming more common. Although there are several published guidelines for the management of gout, actual treatment of gout is inconsistent with these guidelines in many respects. Gout is usually treated by general practitioners (GP) in Germany. The aim of our study was to show which patients present to the emergency department and to record how treatment and clinical diagnostic testing of gout patients is performed in the emergency department of a university hospital in Germany. No such data have been published for Germany. METHOD Retrospective analysis of data of patients with ICD Code M10.xx from the emergency department at a university hospital from 05/2013 until 04/2016. RESULTS 65 patients were treated with acute gout during the study period at the emergency department (age $\emptyset$ 53.45 y, 76.9{\%} male, 23.07{\%} female). 42 patients (65{\%}) came outside normal office hours of GPs. In 31 patients, hyperuricemia or gout was known in their medical history, in 22 of these acute gout was known. 48 (73{\%}) of patients came with monoarthritis and therefrom 40 with {\textquotedbl}classic{\textquotedbl} gout, such as podagra. 57 (86{\%}) patients were subjected to diagnostic blood analysis and 31 (48{\%}) diagnostic X-ray of the affected joint. We defined the appropriate indications for X-ray in diagnosis of acute gout as: signs of superinfection, prior surgical intervention or uncertain trauma in case history. According to this definition, 67{\%} of the X-rays were performed without the correct indication. Four Patients were given punction of the affected joint to demonstrate monosodium urate monohydrate (MSU) crystals. Twelve patients were admitted as inpatients for surgery and/or antibiotic treatment. 51 (78{\%}) patients received NSAIDs, 7 in combination with steroids and 4 patients received colchicine. Of those patients who received NSAID, 17 had an unknown or impaired renal function. Seven patients received neither pharmacological treatment nor recommendations for further treatment. Ten patients (15{\%}) received a urate-lowering therapy or an existing therapy was increased during acute gout. In 10 patients, a urate-lowering therapy was recommended as further therapy. 63{\%} were given further treatment recommendations such as cryotherapy or diet. CONCLUSIONS Acute gout is seldom presented in the emergency room ({\textless} 1‰). This confirms the impression that gout is mainly a disease treated in the outpatient setting. As shown in our study, the pharmacological treatment of acute gout was largely consistent with the guideline recommendations; nevertheless observance of renal function before treatment with NSAIDs should be emphasised. Furthermore, we identified overuse of diagnostic procedures. Current guidelines recommend diagnosing acute gout with clinical scores. In conclusion, our study shows that those clinical diagnostic scores should be implemented in clinical practice, in order to avoid unnecessary diagnostic procedures. HINTERGRUND Die akute Arthritis urica ist eine i. d. R. durch Allgemeinmediziner behandelte Erkrankung. Die Pr{\"a}valenz betr{\"a}gt etwa 1,4{\%} und kommt im h{\"o}heren Lebensalter h{\"a}ufiger vor (bis zu 4,2{\%} bei M{\"a}nnern {\textgreater} 75 Jahre). Bisher wurde in Deutschland noch nicht evaluiert, wann und bei welchen Patienten mit akuter Arthritis urica eine Behandlung in einer zentralen Notaufnahme stattfindet und ob diese leitliniengerecht stattfindet. Diese Studie evaluiert daher Charakteristika und Behandlungspfade von Notfallpatienten mit akutem Gichtanfall in einer zentralen Notaufnahme in Deutschland. METHODEN Retrospektive Analyse der Patienten mit den ICD-Codes M10.xx von 05/2013 bis 04/2016 in der zentralen Notaufnahme eines universit{\"a}ren Krankenhauses. ERGEBNISSE 65 Patienten stellten sich im o. g. Zeitraum aufgrund eines akuten Gichtanfalles vor. 42 Patienten (65{\%}) stellten sich au{\ss}erhalb der Praxis{\"o}ffnungszeiten vor. Anamnestisch gaben 31 (47,69{\%}) Patienten eine bekannte Hyperurik{\"a}mie an, davon 22 (70,96{\%}) mit Gichtanfall in der Vorgeschichte. Es stellten sich 48 (73{\%}) Patienten mit einer Monarthritis vor, davon 40 mit Podagra (68{\%}). Diagnostisch wurde bei 57 (86{\%}) eine Blutentnahme durchgef{\"u}hrt. Eine R{\"o}ntgenaufnahme des betroffenen Gelenks erfolgte bei 31 (48{\%}) Patienten, 67{\%} davon ohne Indikation. Eine Gelenkpunktion mit Kristallnachweis erfolgte bei 4 Patienten. Zw{\"o}lf Patienten (18{\%}) wurden fachspezifisch station{\"a}r aufgenommen zur chirurgischen Revision und/oder antibiotischen Behandlung. 51 Patienten (78{\%}) erhielten prim{\"a}r nicht steroidale Antirheumatika (NSAR), 7 in Kombination mit Glukokortikoiden und 4 Kolchizin. Vor der NSAR-Gabe war bei 17 Patienten die Nierenfunktion nicht bekannt oder eingeschr{\"a}nkt. Elf Patienten (16{\%}) erhielten weder NSAR, Kortison noch Kolchizin. Zehn Patienten (15{\%}) erhielten im akuten Gichtanfall eine harns{\"a}uresenkende Therapie bzw. deren Dosierung wurde ver{\"a}ndert. Zus{\"a}tzlich erhielten 63{\%} der Patienten eine Empfehlung zur Durchf{\"u}hrung nicht medikament{\"o}ser Ma{\ss}nahmen. SCHLUSSFOLGERUNGEN Wir konnten zeigen, dass die pharmakologische Behandlung der Patienten mit einem akuten Gichtanfall gr{\"o}{\ss}tenteils leitliniengerecht erfolgt. Jedoch sollte die Vigilanz bez. der Nierenfunktion vor NSAR-Gabe gesch{\"a}rft werden. {\"U}berwiegend stellten sich die Patienten au{\ss}erhalb der Praxis{\"o}ffnungszeiten vor, was die prim{\"a}r ambulante Versorgung der Gichtpatienten best{\"a}tigt. Die aktuellen Leitlinien empfehlen die Diagnose der unkomplizierten Gicht anhand rein klinischer Diagnosekriterien. Dementgegen fand sich eine {\"U}berversorgung mit diagnostischen Ma{\ss}nahmen in der zentralen Notaufnahme. Abschlie{\ss}end zeigte unsere Untersuchung, dass diese klinischen Diagnosekriterien besser im klinischen Alltag implementiert werden sollten, um unn{\"o}tige R{\"o}ntgen- und Laboruntersuchungen zu vermeiden.},
      author = {Engel, Bettina and Schacher, Sylvia and Weckbecker, Klaus and Stausberg, Annika and Gr{\"a}ff, Ingo},
      year = {2018},
      title = {Der akute Gichtanfall in der zentralen Notaufnahme},
      pages = {653--661},
      volume = {156},
      number = {6},
      journal = {Zeitschrift fur Orthopadie und Unfallchirurgie},
      doi = {10.1055/a-0619-6216},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29986356} }
  • [article] bibtex
    B. Engel, W. Gomm, K. Broich, W. Maier, K. Weckbecker, und B. Haenisch, "Hyperuricemia and dementia - a case-control study" BMC Neurology, vol. 18, iss. 1, p. 131, 2018.
    @article{Engel.2018b, abstract = {BACKGROUND There is evidence that uric acid may have antioxidant and neuroprotective effects and might therefore alter the risk for neurodegenerative diseases such as dementia. So far, the relation between serum uric acid (SUA) levels or hyperuricemia and dementia remains elusive. Most studies focused on the disease or SUA levels. Effects of anti-hyperuricemic treatment have not been considered yet. This study investigated the association between hyperuricemia and dementia taking into account anti-hyperuricemic treatment. METHODS We used longitudinal German public health insurance data and analyzed the association between hyperuricemia with and without different treatment options and dementia in a case-control design. Applying logistic regression the analysis was adjusted for several potential confounders including various comorbidities and polypharmacy. RESULTS We identified 27,528 cases and 110,112 matched controls of which 22{\%} had a diagnosis of hyperuricemia or gout and 17{\%} received anti-hyperuricemic drugs. For patients with a diagnosis of hyperuricemia we found a slightly reduced risk for dementia (adjusted odds ratio [OR] 0.94, 95{\%} confidence interval [CI] 0.89 to 0.98). The risk reduction was more pronounced for patients treated with anti-hyperuricemic drugs (adjusted OR 0.89, 95{\%} CI 0.85 to 0.94, for regular treatment). CONCLUSIONS Our results showed a slight reduction for dementia risk in patients with hyperuricemia, both with and without anti-hyperuricemic treatment.},
      author = {Engel, Bettina and Gomm, Willy and Broich, Karl and Maier, Wolfgang and Weckbecker, Klaus and Haenisch, Britta},
      year = {2018},
      title = {Hyperuricemia and dementia - a case-control study},
      pages = {131},
      volume = {18},
      number = {1},
      journal = {BMC Neurology},
      doi = {10.1186/s12883-018-1136-y},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30170563},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117937} }
  • M. Freckmann, A. Seipp, M. W. Laass, S. Koletzko, M. Classen, A. Ballauff, J. Peplies, und A. Timmer, "School-related experience and performance with inflammatory bowel disease: results from a cross-sectional survey in 675 children and their parents" BMJ Open Gastroenterol, vol. 5, iss. 1, p. 000236, 2018.
    @article{Freckmann.2018,
      author = {Freckmann, M. and Seipp, A. and Laass, Martin W. and Koletzko, Sibylle and Classen, M. and Ballauff, Antje and Peplies, Jenny and Timmer, Antje},
      year = {2018},
      title = {School-related experience and performance with inflammatory bowel disease: results from a cross-sectional survey in 675 children and their parents},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/30538821 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254744/pdf/bmjgast-2018-000236.pdf},
      pages = {e000236},
      volume = {5},
      number = {1},
      issn = {2054-4774},
      journal = {BMJ Open Gastroenterol},
      doi = {10.1136/bmjgast-2018-000236} }
  • S. Hellmers, B. Izadpanah, L. Dasenbrock, R. Diekmann, J. Bauer, A. Hein, und S. Fudickar, "Towards an Automated Unsupervised Mobility Assessment for Older People Based on Inertial TUG Measurements" Sensors, vol. 18, iss. 10, 2018.
    @article{Hellmers.2018b, abstract = {One of the most common assessments for the mobility of older people is the Timed Up and Go test (TUG). Due to its sensitivity regarding the indication of Parkinson's disease (PD) or increased fall risk in elderly people, this assessment test becomes increasingly relevant, should be automated and should become applicable for unsupervised self-assessments to enable regular examinations of the functional status. With Inertial Measurement Units (IMU) being well suited for automated analyses, we evaluate an IMU-based analysis-system, which automatically detects the TUG execution via machine learning and calculates the test duration. as well as the duration of its single components. The complete TUG was classified with an accuracy of 96{\%} via a rule-based model in a study with 157 participants aged over 70 years. A comparison between the TUG durations determined by IMU and criterion standard measurements (stopwatch and automated/ambient TUG (aTUG) system) showed significant correlations of 0.97 and 0.99, respectively. The classification of the instrumented TUG (iTUG)-components achieved accuracies over 96{\%},
      as well. Additionally, the system's suitability for self-assessments was investigated within a semi-unsupervised situation where a similar movement sequence to the TUG was executed. This preliminary analysis confirmed that the self-selected speed correlates moderately with the speed in the test situation, but differed significantly from each other.},
      author = {Hellmers, Sandra and Izadpanah, Babak and Dasenbrock, Lena and Diekmann, Rebecca and Bauer, J{\"u}rgen and Hein, Andreas and Fudickar, Sebastian},
      year = {2018},
      title = {Towards an Automated Unsupervised Mobility Assessment for Older People Based on Inertial TUG Measurements},
      url = {http://www.mdpi.com/1424-8220/18/10/3310},
      volume = {18},
      number = {10},
      journal = {Sensors},
      doi = {10.3390/s18103310},
      file = {Hellmers et al. - 2018 - Towards an Automated Unsupervised Mobility Assessment for Older People Based on Inertial TUG Measurements:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2018 - Towards an Automated Unsupervised Mobility Assessment for Older People Based on Inertial TUG Measurements.pdf:pdf} }
  • [article] bibtex
    C. Lins, A. Gerka, C. Lüpkes, und R. Röhrig, "Enhancing Safety of Artificially Ventilated Patients using Ambient Process Analysis" Stud Health Technol Inform, vol. 247, pp. 316-320, 2018.
    @article{Lins.2018d, abstract = {In this paper, we present an approach for enhancing the safety of artificially ventilated patients using ambient process analysis. We propose to use an analysis system consisting of low-cost ambient sensors such as power sensor, RGB-D sensor, passage detector, and matrix infrared temperature sensor to reduce risks for artificially ventilated patients in both home and clinical environments. We describe the system concept and our implementation and show how the system can contribute to patient safety.},
      author = {Lins, Christian and Gerka, Alexander and L{\"u}pkes, Christian and R{\"o}hrig, Rainer},
      year = {2018},
      title = {Enhancing Safety of Artificially Ventilated Patients using Ambient Process Analysis},
      keywords = {ambient intelligence;ambient process analysis;artificial ventilation;home mechanical;Informationenfehlen;patient safety;Unpublished;ventilation},
      pages = {316--320},
      volume = {247},
      issn = {1879-8365 (Electronic) 0926-9630 (Linking)},
      journal = {Stud Health Technol Inform},
      file = {Lins et al. - 2018 - Enhancing Safety of Artificially Ventilated Patients using Ambient Process Analysis:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins et al. - 2018 - Enhancing Safety of Artificially Ventilated Patients using Ambient Process Analysis.pdf:pdf} }
  • J. L. Magaard, B. Löwe, A. L. Brütt, und S. Kohlmann, "Illness beliefs about depression among patients seeking depression care and patients seeking cardiac care: an exploratory analysis using a mixed method design" BMC Psychiatry, vol. 18, iss. 1, p. 366, 2018.
    @article{Magaard.2018,
      author = {Magaard, J. L. and L{\"o}we, B. and Br{\"u}tt, Anna Levke and Kohlmann, S.},
      year = {2018},
      title = {Illness beliefs about depression among patients seeking depression care and patients seeking cardiac care: an exploratory analysis using a mixed method design},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/30442115},
      pages = {366},
      volume = {18},
      number = {1},
      issn = {1471-244x},
      journal = {BMC Psychiatry},
      doi = {10.1186/s12888-018-1936-z} }
  • J. L. Magaard, S. Liebherz, H. Melchior, A. Engels, H. H. König, L. Kriston, H. Schulz, J. Jahed, A. L. Brütt, K. C. Reber, und M. Härter, "Collaborative mental health care program versus a general practitioner program and usual care for treatment of patients with mental or neurological disorders in Germany: protocol of a multiperspective evaluation study" BMC Psychiatry, vol. 18, iss. 1, p. 347, 2018.
    @article{Magaard.2018b,
      author = {Magaard, J. L. and Liebherz, S. and Melchior, H. and Engels, A. and K{\"o}nig, H. H. and Kriston, L. and Schulz, H. and Jahed, J. and Br{\"u}tt, Anna Levke and Reber, K. C. and H{\"a}rter, Martin},
      year = {2018},
      title = {Collaborative mental health care program versus a general practitioner program and usual care for treatment of patients with mental or neurological disorders in Germany: protocol of a multiperspective evaluation study},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/30359248},
      pages = {347},
      volume = {18},
      number = {1},
      issn = {1471-244x},
      journal = {BMC Psychiatry},
      doi = {10.1186/s12888-018-1914-5} }
  • [article] bibtex
    A. Pérez-Fortis, J. Fleer, M. J. Schroevers, P. Alanís-López, J. J. Sánchez Sosa, C. Eulenburg, und A. V. Ranchor, "Course and predictors of supportive care needs among Mexican breast cancer patients: A longitudinal study" Psycho-oncology, vol. 27, iss. 9, pp. 2132-2140, 2018.
    @article{PerezFortis.2018, abstract = {OBJECTIVE This study examined the course and predictors of supportive care needs among Mexican breast cancer patients for different cancer treatment trajectories. METHODS Data from 172 (66.4{\%} response rate) patients were considered in this observational longitudinal study. Participants were measured after diagnosis, neoadjuvant treatment, surgery, adjuvant treatment, and the first post-treatment follow-up visit. Psychological, Health System and Information, Physical and Daily Living, Patient Care and Support, Sexual, and Additional care needs were measured with the Supportive Care Needs Survey (SCNS-SF34). Linear mixed models with maximum-likelihood estimation were computed. RESULTS The course of supportive care needs was similar across the different cancer treatment trajectories. Supportive care needs declined significantly from diagnosis to the first post-treatment follow-up visit. Health System and Information care needs were the highest needs over time. Depressive symptoms and time since diagnosis were the most consistent predictors of changes in course of supportive care needs of these patients. CONCLUSIONS Health system and information care needs of Mexican breast cancer patients need to be addressed with priority because these needs are the least met. Furthermore, patients with high depressive symptoms at the start of the disease trajectory have greater needs for supportive care throughout the disease trajectory.},
      author = {P{\'e}rez-Fortis, Adriana and Fleer, Joke and Schroevers, Maya J. and Alan{\'i}s-L{\'o}pez, Patricia and {S{\'a}nchez Sosa},
      Juan Jos{\'e} and Eulenburg, Christine and Ranchor, Adelita V.},
      year = {2018},
      title = {Course and predictors of supportive care needs among Mexican breast cancer patients: A longitudinal study},
      pages = {2132--2140},
      volume = {27},
      number = {9},
      journal = {Psycho-oncology},
      doi = {10.1002/pon.4778},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29802674},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175400} }
  • [article] bibtex
    D. Pieper und K. Allers, "Differences between protocols for randomized controlled trials and systematic reviews" Journal of Clinical Epidemiology, vol. S0895-4356, iss. 17, pp. 31202-31207, 2018.
    @article{Pieper.2018,
      author = {Pieper, Dawid and Allers, Katharina},
      year = {2018},
      title = {Differences between protocols for randomized controlled trials and systematic reviews},
      keywords = {*Research Design;*Systematic Reviews as Topic;Randomized Controlled Trials as Topic/*methods},
      pages = {31202--31207},
      volume = {S0895-4356},
      number = {17},
      issn = {0895-4356},
      journal = {Journal of Clinical Epidemiology},
      doi = {10.1016/j.jclinepi.2017.11.027} }
  • [article] bibtex
    I. Redeker, F. Hoffmann, J. Callhoff, H. Haibel, J. Sieper, A. Zink, und D. Poddubnyy, "Response to 'Missing pebble in the mosaic of rheumatic diseases and mental health: younger does not always mean happier' by Alunno et al" Ann Rheum Dis, vol. 78, iss. 6, p. 55, 2018.
    @article{Redeker.2018,
      author = {Redeker, Imke and Hoffmann, Falk and Callhoff, Johanna and Haibel, Hildrun and Sieper, Joachim and Zink, Angela and Poddubnyy, Denis},
      year = {2018},
      title = {Response to 'Missing pebble in the mosaic of rheumatic diseases and mental health: younger does not always mean happier' by Alunno et al},
      keywords = {*ankylosing spondylitis;*psychology;*Rheumatic Diseases;*Spondylarthritis;*Spondylitis, Ankylosing;*spondyloarthritis;Humans;Mental Health;Patient Reported Outcome Measures;Surveys and Questionnaires},
      pages = {e55},
      volume = {78},
      number = {6},
      issn = {0003-4967},
      journal = {Ann Rheum Dis},
      doi = {10.1136/annrheumdis-2018-213620} }
  • [article] bibtex
    G. Torbahn, H. Hofmann, G. Rücker, K. Bischoff, M. H. Freitag, R. Dersch, V. Fingerle, E. Motschall, J. J. Meerpohl, und C. Schmucker, "Efficacy and Safety of Antibiotic Therapy in Early Cutaneous Lyme Borreliosis: A Network Meta-analysis" JAMA dermatology, vol. 154, iss. 11, pp. 1292-1303, 2018.
    @article{Torbahn.2018, abstract = {Importance Controversies about the choice of antibiotic agent and treatment modality exist in the management of erythema migrans in early cutaneous Lyme borreliosis (LB). Objective To conduct a network meta-analysis (NMA) of all randomized clinical trials on various antibiotic agents and treatment modalities in early cutaneous LB. Data Sources Electronic searches in MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials were conducted from inception until July 2017. The reference lists of the included studies were hand searched,
      authors were contacted, and ongoing trials were searched at ClinicalTrials.gov. Study Selection One reviewer screened the titles and abstracts of the 9975 reports identified by the electronic searches. Full-text copies of 161 potentially relevant articles were obtained, and 2 reviewers independently assessed those articles for inclusion. Adults with a physician-confirmed early localized skin infection who were treated with antibiotics of any dose or duration were included. Data Extraction and Synthesis Two reviewers independently extracted data on study, patient, and intervention characteristics. Network meta-analyses on treatment effects and adverse outcomes were calculated with a frequentist approach using the R package netmeta. The Grading of Recommendations Assessment, Development and Evaluation guidance for NMA was used to assess the certainty of evidence. Main Outcomes and Measures Treatment effects for response to treatment (resolution of symptoms) and treatment-related adverse events. Results Overall, 19 studies (2532 patients) were included. The mean patient age ranged between 37 and 56 years, and the percentage of female patients ranged from 36{\%} to 60{\%}. The antibiotics investigated were doxycycline, cefuroxime axetil, ceftriaxone, amoxicillin, azithromycin, penicillin V, and minocycline. Pooled effect sizes from NMAs did not suggest any significant differences in treatment response by antibiotic agent (eg, amoxicillin vs doxycycline odds ratio, 1.26; 95{\%} CI, 0.41-3.87), dose, or duration (eg, doxycycline, 200 mg/d for 3 weeks, vs doxycycline, 200 mg/d for 2 weeks, odds ratio, 1.28; 95{\%} CI, 0.49-3.34). Treatment failures were rare at both 2 months (4{\%}; 95{\%} CI, 2{\%}-5{\%}) and 12 months (2{\%},
      95{\%} CI, 1{\%}-3{\%}) after treatment initiation. There were also no differences in the effect sizes among antibiotic agents and treatment modalities for treatment-related adverse outcomes, which were generally mild to moderate. Certainty of evidence was categorized as low and very low mostly because of imprecision, indirectness, and study limitations (high risk of bias) of the included studies. Conclusions and Relevance This NMA suggests that neither the antibiotic agent nor treatment modality contributed to comparative effectiveness or drug-related adverse outcomes. This finding is relevant for physicians treating patients with LB and for patient decision making.},
      author = {Torbahn, Gabriel and Hofmann, Heidelore and R{\"u}cker, Gerta and Bischoff, Karin and Freitag, Michael H. and Dersch, Rick and Fingerle, Volker and Motschall, Edith and Meerpohl, J{\"o}rg J. and Schmucker, Christine},
      year = {2018},
      title = {Efficacy and Safety of Antibiotic Therapy in Early Cutaneous Lyme Borreliosis: A Network Meta-analysis},
      pages = {1292--1303},
      volume = {154},
      number = {11},
      journal = {JAMA dermatology},
      doi = {10.1001/jamadermatol.2018.3186},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30285069},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248135} }
  • [article] bibtex
    S. Zeike, L. Ansmann, L. Lindert, C. Samel, C. Kowalski, und H. Pfaff, "Identifying cut-off scores for job demands and job control in nursing professionals: a cross-sectional survey in Germany" BMJ open, vol. 8, iss. 12, p. 021366, 2018.
    @article{Zeike.2018, abstract = {OBJECTIVES Nurses are generally found to be vulnerable to burnout, but nurses working in cancer care are even more so, since this profession is characterised by continuous confrontation with suffering and death. This study was designed to identify cut-off scores for job strain, that is, low job control and high job demands, for a sample of nurses working in breast cancer care. The main goal was to find cut-off scores, which predict the risk of nurses of developing a mental disorder from high job strain. DESIGN The design was a cross-sectional survey study. SETTING The study is based on an employee survey in breast cancer centres in Germany. PARTICIPANTS 688 nurses received a questionnaire; 329 nurses from 33 hospitals participated in the survey (return rate: 50.2{\%}). PRIMARY AND SECONDARY OUTCOME MEASURES Dependent variable: psychological well-being, measured by the WHO-5 Well-being Index; independent variables: job control and job demands, measured by the Job Content Questionnaire (JCQ). RESULTS Multivariable analysis indicates that low job control and high job demands are prognostic factors for low well-being. In a receiver operating curve (ROC) analysis, the cut-off scores, which demonstrated a maximum Youden index, were 34.5 for job control and 31.4 for job demands. The combination of both scales from a logistic regression analysis resulted in an area under the curve of 0.778. Sensitivity and specificity are 70.3{\%} and 74.2{\%},
      respectively. The total of correct classification was 63.3{\%}. CONCLUSION The determined cut-off scores indicate that there is a risk of becoming psychologically ill from a high workload when an individual reaches a score of $\leq$34.5 for job control and $\geq$31.4 for job demands. The described method of establishing risk-based cut-off scores is promising for nursing practice and for the field of occupational health. Transferability and generalisability of the cut-off scores should be further analysed.},
      author = {Zeike, Sabrina and Ansmann, Lena and Lindert, Lara and Samel, Christina and Kowalski, Christoph and Pfaff, Holger},
      year = {2018},
      title = {Identifying cut-off scores for job demands and job control in nursing professionals: a cross-sectional survey in Germany},
      pages = {e021366},
      volume = {8},
      number = {12},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2017-021366},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30530574},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303688} }
  • [inproceedings] bibtex
    A. Brinkmann, C. Fifelski, A. Meier, R. Diekmann, und A. Hein, "Reconstruction of Skeletal Muscle Architecture from DT-MRI Sequences" in Proc. Proceedings of 5th Annual Conf. on Computational Science & Computational Intelligence - CSCI '18, Oldenburg, 2018, p. 4.
    @inproceedings{Brinkmann.2018, abstract = {Sarcopenia is defined as a muscle disease rooted in the continuous loss of muscle mass, strength and function. In terms of human health, sarcopenia leads to mobility disorders, increases the risk of falls and fractures and contributes to a lowered quality of life. Therefore, an early detection is essential for those suffering from sarcopenia. The rectus femoris muscle (RF) is suspected to be an early biomarker of sarcopenia in older adults. In this work the possibility of using MeVisLab as a muscle-specific diffusion tensor-magnetic resonance imaging (DTMRI) software tool is analyzed. It turned out that MeVisLab is a powerful tool to perform muscle-specific processing and fiber tracking. The plausibility of the results is going to be discussed for further application in studies.},
      author = {Brinkmann, Anna and Fifelski, Conrad and Meier, Angelika and Diekmann, Rebecca and Hein, Andreas},
      title = {Reconstruction of Skeletal Muscle Architecture from DT-MRI Sequences},
      keywords = {accepted;Informationenfehlen;short paper;UNIAMT;UNIITA;Unpublished},
      pages = {4},
      publisher = {CPS},
      booktitle = {Proceedings of 5th Annual Conf. on Computational Science {\&} Computational Intelligence - CSCI '18},
      year = {2018},
      address = {Oldenburg},
      file = {Brinkmann et al. - 2018 - Reconstruction of Skeletal Muscle Architecture from DT-MRI Sequences:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Brinkmann et al. - 2018 - Reconstruction of Skeletal Muscle Architecture from DT-MRI Sequences.pdf:pdf} }
  • [inproceedings] bibtex
    C. Fifelski, A. Brinkmann, S. M. Ortmann, M. Isken, und A. Hein, "Multi Depth Camera System for 3D Data Recording for Training and Education of Nurses" in Proc. Proceedings of 5th Annual Conf. on Computational Science & Computational Intelligence - CSCI '18, Oldenburg, 2018, p. 6.
    @inproceedings{Fifelski.2018, abstract = {The demographic change in Germany causes a growing number of people over 65 years, which leads to an imbalance between potential recipients and providers of the services of the health care systems, i.e. nurses. Because nursing is a physically challenging activity, there is an urgent need for appropriate training and guidance to reduce the risk of musculoskeletal overload and therefore the high sick leave in this profession. Consequently, we developed a new complex sensor system, consisting of multiple Microsoft Kinect V2 depth cameras, to record care scenarios for educational purposes for health care professionals. This system provides the possibility to view the care actions from infinite points of view and can record the data to give personalized feedback. This paper describes and presents our sensor system in a technical manner and shows how care instructors use our system to educate nurses.},
      author = {Fifelski, Conrad and Brinkmann, Anna and Ortmann, Simon Martin and Isken, Melvin and Hein, Andreas},
      title = {Multi Depth Camera System for 3D Data Recording for Training and Education of Nurses},
      keywords = {accepted;computer aided analysis;educational tech-nology;full paper;Health care;Index Terms-Sensor systems;Informationenfehlen;UNIAMT;UNIITA;Unpublished},
      pages = {6},
      publisher = {CPS},
      booktitle = {Proceedings of 5th Annual Conf. on Computational Science {\&} Computational Intelligence - CSCI '18},
      year = {2018},
      address = {Oldenburg},
      file = {Fifelski et al. - 2018 - Multi Depth Camera System for 3D Data Recording for Training and Education of Nurses:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Fifelski et al. - 2018 - Multi Depth Camera System for 3D Data Recording for Training and Education of Nurses.pdf:pdf} }
  • [inproceedings] bibtex
    A. Münzberg, J. Sauer, A. Hein, und N. Rösch, "The use of ETL and data profiling to integrate data and improve quality in food databases" in Proc. 14th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob), Limassol, 2018, pp. 231-238.
    @inproceedings{Munzberg.2018, abstract = {This paper focuses on integrating food data sources into a central database using extract, transform and load processing and the subsequent data quality enhancement. The obtained data will be transmitted by a food data web service to certain health apps for further use. Furthermore, it is planned to identify inconsistent, incorrect, duplicate and incomplete data using methods of data profiling so that they can be corrected. In order to quantify the data quality purposefully and appropriately, certain quality metrics were used. These metrics were calculated and evaluated using random test data selected from the food data.},
      author = {M{\"u}nzberg, Alexander and Sauer, Janina and Hein, Andreas and R{\"o}sch, Norbert},
      title = {The use of ETL and data profiling to integrate data and improve quality in food databases},
      keywords = {data profiling;data quality improvement;data quality metrics;data warehousing;ETL process;food data;food information service},
      pages = {231--238},
      booktitle = {14th International Conference on Wireless and Mobile Computing, Networking and Communications (WiMob)},
      year = {2018},
      address = {Limassol},
      doi = {10.1109/WiMOB.2018.8589081},
      file = {Münzberg et al. - 2018 - The use of ETL and data profiling to integrate data and improve quality in food databases:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Münzberg et al. - 2018 - The use of ETL and data profiling to integrate data and improve quality in food databases.pdf:pdf} }
  • [article] bibtex
    K. Allers und F. Hoffmann, "Mortality and hospitalization at the end of life in newly admitted nursing home residents with and without dementia" Soc Psychiatry Psychiatr Epidemiol, vol. 53, iss. 8, pp. 833-839, 2018.
    @article{Allers.2018b, abstract = {PURPOSE: The proportion of deaths occurring in nursing homes is increasing and end of life hospitalizations in residents are common. This study aimed to obtain the time from nursing home admission to death and the frequency of hospitalizations prior to death among residents with and without dementia. METHODS: This retrospective cohort study analyzed claims data of 127,227 nursing home residents aged 65~years and older newly admitted to a nursing home between 2010 and 2014. We analyzed hospitalizations during the last year of life and assessed mortality rates per 100 person-years. Factors potentially associated with time to death were analyzed in Cox proportional hazard models. RESULTS: The median time from nursing home admission to death was 777 and 635 days in residents with and without dementia, respectively. Being male, older age and a higher level of care decreased the survival time. Sex and age had a higher influence on survival time in residents with dementia, whereas level of care was found to have a higher influence in residents without dementia. Half of the residents of both groups were hospitalized during the last month and about 37{\%} during the last week before death. Leading causes of hospitalizations were infections (with dementia: 20.6{\%} vs. without dementia: 17.2{\%}) and cardiovascular diseases (with dementia: 16.6{\%} vs. without dementia: 19.0{\%}). CONCLUSIONS: A high proportion of residents with and without dementia are hospitalized shortly before death. There should be an open debate about the appropriateness of hospitalizing nursing home residents especially those with dementia near death.},
      author = {Allers, Katharina and Hoffmann, Falk},
      year = {2018},
      title = {Mortality and hospitalization at the end of life in newly admitted nursing home residents with and without dementia},
      keywords = {Aged;Aged, 80 and over;Dementia;Dementia/*mortality/nursing;End of life;Female;Hospitalization;Hospitalization/*statistics {\&} numerical data;Humans;Male;Mortality;nursing home;Nursing Homes/*statistics {\&} numerical data;Proportional Hazards Models;Retrospective Studies;Terminal Care/*statistics {\&} numerical data},
      pages = {833--839},
      volume = {53},
      number = {8},
      issn = {0933-7954},
      journal = {Soc Psychiatry Psychiatr Epidemiol},
      doi = {10.1007/s00127-018-1523-0} }
  • [article] bibtex
    B. Andersen, M. Kasparick, H. Ulrich, S. Franke, J. Schlamelcher, M. Rockstroh, und J. Ingenerf, "Connecting the clinical IT infrastructure to a service-oriented architecture of medical devices" Biomedical Engineering / Biomedizinische Technik, vol. 63, iss. 1, pp. 57-68, 2018.
    @article{Andersen.2018, abstract = {The new medical device communication protocol known as IEEE 11073 SDC is well-suited for the integration of (surgical) point-of-care devices, so are the established Health Level Seven (HL7) V2 and Digital Imaging and Communications in Medicine (DICOM) standards for the communication of systems in the clinical IT infrastructure (CITI). An integrated operating room (OR) and other integrated clinical environments, however, need interoperability between both domains to fully unfold their potential for improving the quality of care as well as clinical workflows. This work thus presents concepts for the propagation of clinical and administrative data to medical devices, physiologic measurements and device parameters to clinical IT systems, as well as image and multimedia content in both directions. Prototypical implementations of the derived components have proven to integrate well with systems of networked medical devices and with the CITI, effectively connecting these heterogeneous domains. Our qualitative evaluation indicates that the interoperability concepts are suitable to be integrated into clinical workflows and are expected to benefit patients and clinicians alike. The upcoming HL7 Fast Healthcare Interoperability Resources (FHIR) communication standard will likely change the domain of clinical IT significantly. A straightforward mapping to its resource model thus ensures the tenability of these concepts despite a foreseeable change in demand and requirements.},
      author = {Andersen, Bj{\"o}rn and Kasparick, Martin and Ulrich, Hannes and Franke, Stefan and Schlamelcher, Jan and Rockstroh, Max and Ingenerf, Josef},
      year = {2018},
      title = {Connecting the clinical IT infrastructure to a service-oriented architecture of medical devices},
      keywords = {clinical information systems;computer-assisted surgery;IEEE 11073 SDC;integrated operating room;medical communication standards;medical device interoperability},
      pages = {57--68},
      volume = {63},
      number = {1},
      journal = {Biomedical Engineering / Biomedizinische Technik},
      doi = {10.1515/bmt-2017-0021},
      file = {Andersen et al. - 2018 - Connecting the clinical IT infrastructure to a service-oriented architecture of medical devices:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Andersen et al. - 2018 - Connecting the clinical IT infrastructure to a service-oriented architecture of medical devices.pdf:pdf} }
  • [article] bibtex
    H. Claessen, M. Narres, B. Haastert, W. Arend, F. Hoffmann, S. Morbach, G. Rümenapf, T. Kvitkina, H. Friedel, C. Günster, I. Schubert, W. Ullrich, B. Westerhoff, A. Wilk, und A. Icks, "Lower-extremity amputations in people with and without diabetes in Germany, 2008-2012 - an analysis of more than 30 million inhabitants" Clinical Epidemiology, vol. 10, pp. 475-488, 2018.
    @article{Claessen.2018, abstract = {BACKGROUND AND PURPOSE: Lower-extremity amputations (LEAs) in people with diabetes are associated with reduced quality of life and increased health care costs. Detailed knowledge on amputation rates (ARs) is of utmost importance for future health care and economics strategies. We conducted the present cohort study in order to estimate the incidences of LEA as well as relative and attributable risk due to diabetes and to investigate time trends for the period 2008-2012. METHODS: On the basis of the administrative data from three large branches of German statutory health insurers, covering {\~{}}34 million insured people nationwide (about 40{\%} of the German population), we estimated age-sex-standardized AR (first amputation per year) in the populations with and without diabetes for any, major, and minor LEAs. Time trends were analyzed using Poisson regression. RESULTS: A total of 108,208 individuals (diabetes: 67.3{\%}; mean age 72.6 years) had at least one amputation. Among people with diabetes, we observed a significant reduction in major and minor ARs during 2008-2012 from 81.2 (95{\%} CI 77.5-84.9) to 58.4 (55.0-61.7), and from 206.1 (197.3-214.8) to 177.0 (169.7-184.4) per 100,000 person-years, respectively. Among people without diabetes, the major AR decreased significantly from 14.3 (13.9-14.8) to 11.6 ([11.2-12.0], 12.0), whereas the minor AR increased from 15.8 (15.3-16.3) to 17.0 (16.5-17.5) per 100,000 person-years. The relative risk (RR) comparing the diabetic with the nondiabetic populations decreased significantly for both major and minor LEAs (4{\%} and 5{\%} annual reduction, respectively). CONCLUSION: In this large nationwide population, we still found higher major and minor ARs among people with diabetes compared with those without diabetes. However, AR and RR of major and minor LEAs in the diabetic compared with the nondiabetic population decreased significantly during the study period, confirming a positive trend that has been observed in smaller and regional studies in recent years.},
      author = {Claessen, H. and Narres, M. and Haastert, Burkhard and Arend, W. and Hoffmann, Falk and Morbach, S. and R{\"u}menapf, G. and Kvitkina, T. and Friedel, H. and G{\"u}nster, C. and Schubert, I. and Ullrich, W. and Westerhoff, B. and Wilk, A. and Icks, Andrea},
      year = {2018},
      title = {Lower-extremity amputations in people with and without diabetes in Germany, 2008-2012 - an analysis of more than 30 million inhabitants},
      keywords = {amputation rate;cohort study;diabetes;Epidemiology;incidence;lower-extremity amputations;relative risk;time trend},
      pages = {475--488},
      volume = {10},
      issn = {1179-1349 (Print) 1179-1349},
      journal = {Clinical Epidemiology},
      doi = {10.2147/clep.S146484},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916260} }
  • [article] bibtex
    M. Dörks, S. Herget-Rosenthal, F. Hoffmann, und K. Jobski, "Combined use of drugs inhibiting the renin-angiotensin system: prescribing patterns and risk of acute kidney injury in German nursing home residents" Clin Interv Aging, vol. 13, pp. 1035-1042, 2018.
    @article{Dorks.2018, abstract = {BACKGROUND/AIMS: In 2012, the European Medicines Agency reviewed the safety of dual renin-angiotensin system (RAS) blockade because of potentially increased risks for inter alia acute kidney injury (AKI). Since residents of nursing homes are particularly vulnerable to adverse drug outcomes, the aims of our study were to describe RAS-inhibiting drug use in German nursing home residents and examine the risk of AKI associated with dual RAS blockade. METHODS: Based on claims data, a nested case-control study within a cohort of RAS-inhibiting drug users was conducted. Using conditional logistic regression, confounder-adjusted odds ratios (aORs) and 95{\%} confidence intervals (CI) were obtained for the risk of AKI associated with dual RAS blockade. Subgroup analyses were performed in patients with diabetes or chronic kidney disease and both comorbidities. RESULTS: Of all 127,227 nursing home residents, the study cohort included 64,567 (50.7{\%}) who were treated with at least one RAS-inhibiting drug. More than three quarters of the study population were female (77.1{\%}). Mean age was 86.0 $\pm$ 6.8 years. Most residents were treated with angiotensin-converting enzyme inhibitors (77.8{\%}), followed by angiotensin II receptor blockers (21.6{\%}) and aliskiren (0.2{\%}). Annual prevalence of dual RAS blockade declined from 9.6 (95{\%} CI 7.8-11.8) in 2010 to 4.7 (95{\%} CI 4.0-5.4) per 1,000 users in 2014. In the overall cohort, AKI was not significantly associated with dual RAS blockade (aOR 1.99; 0.77-5.17). However, significantly increased aORs were observed when considering patients with diabetes (3.47; 1.27-9.47), chronic kidney disease (4.74; 1.24-18.13) or both (11.17; 2.65-47.15). CONCLUSIONS: Prescribing of drugs inhibiting the RAS is common in German nursing homes. Though the prevalence of dual RAS blockade declined, our study showed an increased risk of AKI in patients with diabetes and/or chronic kidney disease. Therefore, cautious use is warranted in these vulnerable patients.},
      author = {D{\"o}rks, Michael and Herget-Rosenthal, Stefan and Hoffmann, Falk and Jobski, Kathrin},
      year = {2018},
      title = {Combined use of drugs inhibiting the renin-angiotensin system: prescribing patterns and risk of acute kidney injury in German nursing home residents},
      keywords = {Acute Kidney Injury/*epidemiology;Aged;Aged, 80 and over;Amides/*therapeutic use;Angiotensin Receptor Antagonists/*therapeutic use;Angiotensin-Converting Enzyme Inhibitors/*therapeutic use;Antihypertensive Agents/*therapeutic use;Case-Control Studies;Cohort Studies;Diabetes Mellitus/epidemiology;Drug Prescriptions/statistics {\&} numerical data;Drug Therapy, Combination/statistics {\&} numerical data;dual RAS blockade;Female;Fumarates/*therapeutic use;Germany/epidemiology;Humans;Long-term care;Male;nested case-control study;Nursing homes;Renal Insufficiency, Chronic/epidemiology;Renin-Angiotensin System;Risk Factors},
      pages = {1035--1042},
      volume = {13},
      issn = {1176-9092 (Print) 1176-9092},
      journal = {Clin Interv Aging},
      doi = {10.2147/cia.S159715},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973467} }
  • S. Fudickar, C. Stolle, N. Volkening, und A. Hein, "Scanning Laser Rangefinders for the Unobtrusive Monitoring of Gait Parameters in Unsupervised Settings" Sensors, vol. 18, iss. 10, p. 3424, 2018.
    @article{Fudickar.2018, abstract = {Since variations in common gait parameters (such as cadence, velocity and stride-length) of elderly people are a reliable indicator of functional and cognitive decline in aging and increased fall risks, such gait parameters have to be monitored continuously to enable preventive interventions as early as possible. With scanning laser rangefinders (SLR) having been shown to be suitable for standardised (frontal) gait assessments, this article introduces an unobtrusive gait monitoring (UGMO) system for lateral gait monitoring in homes for the elderly. The system has been evaluated in comparison to a GAITRite (as reference system) with 86 participants (ranging from 21 to 82 years) passing the 6-min walk test twice. Within the considered 56,351 steps within an overall 7877 walks and approximately 34 km distance travelled, it has been shown that the SLR Hokuyo UST10-LX is more sensitive than the cheaper URG-04LX version in regard to the correct (automatic) detection of lateral steps (98{\%} compared to 77{\%}) and walks (97{\%} compared to 66{\%}). Furthermore, it has been confirmed that the UGMO (with the SLR UST10-LX) can measure gait parameters such as gait velocity and stride length with sufficient sensitivity to determine age- and disease-related functional (and cognitive) decline.},
      author = {Fudickar, Sebastian and Stolle, Christian and Volkening, Nils and Hein, Andreas},
      year = {2018},
      title = {Scanning Laser Rangefinders for the Unobtrusive Monitoring of Gait Parameters in Unsupervised Settings},
      url = {http://www.mdpi.com/1424-8220/18/10/3424},
      pages = {3424},
      volume = {18},
      number = {10},
      journal = {Sensors},
      doi = {10.3390/s18103424},
      file = {Fudickar et al. - 2018 - Scanning Laser Rangefinders for the Unobtrusive Monitoring of Gait Parameters in Unsupervised Settings:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Fudickar et al. - 2018 - Scanning Laser Rangefinders for the Unobtrusive Monitoring of Gait Parameters in Unsupervised Settings.pdf:pdf} }
  • [article] bibtex
    H. Jacobs, H. Zeeb, und F. Hoffmann, "Incidence Rates of and Mortality after Hip Fracture among German Nursing Home Residents" Int J Environ Res Public Health, vol. 15, iss. 2, 2018.
    @article{Jacobs.2018, abstract = {Little is known about hip fracture rates and post-fracture mortality among nursing home residents. This retrospective cohort study examined incidence rates (IR) of and mortality after hip fracture in this population focusing on sex differences. A cohort of {\textgreater}127,000 residents $\geq$65 years, newly admitted to German nursing homes between 2010 and 2014 were used to calculate age-, sex-, care-need- and time after admission-specific IR. To determine mortality, the Kaplan-Meier-method was applied. Using Cox regression, we studied mortality and estimated time-dependent hazard ratios (HRs). For this purpose, to each person with a hip fracture, one resident without a hip fracture was matched by sex, age and care-need using risk-set sampling. 75{\%} were women (mean age: 84.0 years). During 168,588 person-years (PY), 8537 residents with at least one hip fracture were observed. The IR for women and men were 52.9 and 42.5/1000 PY. For both sexes, IR increased with rising age and decreased with increasing care-level. IR were highest in the first months after admission and subsequently declined afterwards. The impact of hip fractures on mortality was time-dependent. Mortality of residents with hip fracture was highest in the first two months after fracture compared to those without (HR): 2.82; 95{\%} CI 2.57-3.11) and after six months, no differences were found (HR: 1.10; 95{\%} CI 0.98-1.22) Further research should always include analyses stratified by sex, age and time period after admission.},
      author = {Jacobs, Hannes and Zeeb, Hajo and Hoffmann, Falk},
      year = {2018},
      title = {Incidence Rates of and Mortality after Hip Fracture among German Nursing Home Residents},
      keywords = {*Health services research;*hip fracture;*Homes for the Aged;*incidence rate;*Mortality;*nursing home;*Nursing Homes;Aged;Aged, 80 and over;Female;Germany/epidemiology;Hip Fractures/*epidemiology/mortality;Hospitalization;Humans;incidence;Male;Retrospective Studies;Risk;Survival Analysis},
      volume = {15},
      number = {2},
      issn = {1661-7827 (Print) 1660-4601},
      journal = {Int J Environ Res Public Health},
      doi = {10.3390/ijerph15020289},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858358} }
  • B. S. Löffler, H. I. Stecher, S. Fudickar, D. de Sordi, F. Otto-Sobotka, A. Hein, und C. S. Herrmann, "Counteracting the Slowdown of Reaction Times in a Vigilance Experiment With 40-Hz Transcranial Alternating Current Stimulation" IEEE Trans Neural Syst Rehabil Eng, vol. 26, iss. 10, pp. 2053-2061, 2018.
    @article{Loffler.2018, abstract = {Indicators for a decrement in vigilance are a slowdown in reaction times and an increase in alpha power in the electroencephalogram (EEG) in posterior regions of the brain. Transcranial alternating current stimulation (tACS) is a neuropsychological technique that has been found to interact with intrinsic brain oscillations and is able to enhance cognitive and behavioral performance. Recent studies showed that tACS in the gamma frequency range (30-80 Hz) is able to downregulate amplitudes in the alpha frequency range (8-12 Hz), in accordance to the effect referred to as cross-frequency coupling, where intrinsic alpha and gamma waves modulate each other. We applied 40 Hz gamma-tACS to the visual cortex during a vigilance experiment and investigated if stimulation improves reaction times and error rates with time-on-task. In our sham controlled experiment, participants completed two blocks of 30 minutes duration while performing the same visual two-choice task. The first block was used as BASELINE. A statistical analysis with a linear mixed model (LMM) revealed a significantly lower increase of modeled reaction times over time in the INTERVENTION-block of the tACS-group as compared to their BASELINE-block whereas there was no significant change between the BASELINE- and INTERVENTION-block for the SHAM-group. Error rates did not differ between groups. This study indicates that gamma-tACS can enhance performance in vigilance tasks as it significantly decreased the slowdown of reaction times in our study.},
      author = {L{\"o}ffler, Birte Sofie and Stecher, H. I. and Fudickar, Sebastian and {de Sordi},
      D. and Otto-Sobotka, F. and Hein, Andreas and Herrmann, Christoph S.},
      year = {2018},
      title = {Counteracting the Slowdown of Reaction Times in a Vigilance Experiment With 40-Hz Transcranial Alternating Current Stimulation},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/30207962 https://ieeexplore.ieee.org/document/8458158/},
      pages = {2053--2061},
      volume = {26},
      number = {10},
      journal = {IEEE Trans Neural Syst Rehabil Eng},
      doi = {10.1109/TNSRE.2018.2869471},
      file = {Löffler et al. - 2018 - Counteracting the Slowdown of Reaction Times in a Vigilance Experiment with 40 Hz Transcranial Alternating Curre:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Löffler et al. - 2018 - Counteracting the Slowdown of Reaction Times in a Vigilance Experiment with 40 Hz Transcranial Alternating Curre.pdf:pdf} }
  • [article] bibtex
    A. Luque Ramos, F. Hoffmann, und O. Spreckelsen, "Waiting times in primary care depending on insurance scheme in Germany" BMC Health Services Research, vol. 18, iss. 1, p. 191, 2018.
    @article{LuqueRamos.2018, abstract = {BACKGROUND: Waiting times for an outpatient appointment in Germany differ between insurants of the statutory and private health insurance schemes, especially for specialised care. The aim of this study was to uncover possible differences in waiting times depending on health insurance scheme and to identify predictors for excessive waiting times in primary care. METHODS: We used data of the Bertelsmann Foundation Healthcare Monitor, which is a repeated cross sectional study dealing with experiences in health care and attitudes towards current health policy themes. We analysed the surveys conducted from 2011 to 2013, with respondents assigned to their health insurance fund, namely AOK, BARMER GEK, BKK, DAK, TK, IKK, other statutory funds and private funds. The mean waiting times for an appointment and spent in a physician's waiting room, and the satisfaction with waiting times were evaluated with respect to different health insurance funds. A logistic regression model was used to calculate the chance of excessive waiting times with respect to health insurance fund, age, sex, health and socioeconomic status. The ninetieth percentile of the waiting time distribution (10 days) was chosen as the cut-off point between average and excessive. RESULTS: A total of 5618 respondents were analysed. Mean waiting times in primary care were low (4.0 days) and homogeneous (SHIs: 3.6-4.9 days), even though privately insured respondents reported shorter waiting times for appointments (3.3 days). They also reported a greater satisfaction with waiting times (77.5{\%}) than SHI insurants (64.5{\%}). However, we identified a group (10.1{\%}), who experienced excessive waiting times in primary care. Compared to privately insured respondents, the chance of excessive waiting times was increased for SHI insurants (highest odds ratio for BKK: 2.17; 95{\%}-CI: 1.38-3.42). Additionally, higher age and residence in East Germany were associated with higher chances of waiting times of 10 days or more. CONCLUSIONS: Primary care in Germany is readily accessible with generally short waiting times. However, barriers in access to the health care system affect a certain part of patients depending on insurance status, age and region of residence. Ways to improve the access need to be studied.},
      author = {{Luque Ramos},
      A. and Hoffmann, Falk and Spreckelsen, Ove},
      year = {2018},
      title = {Waiting times in primary care depending on insurance scheme in Germany},
      keywords = {*Health Services Accessibility;*Primary Health Care;*Private health insurance;*Social inequality;*Statutory health insurance;*Waiting Lists;*Waiting times;Cross-Sectional Studies;Female;Germany;Humans;Insurance, Health/*statistics {\&} numerical data;Male;Middle Aged;Time Factors},
      pages = {191},
      volume = {18},
      number = {1},
      journal = {BMC Health Services Research},
      doi = {10.1186/s12913-018-3000-6},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29558925},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5859448} }
  • [article] bibtex
    L. Martini und F. Hoffmann, "Comorbidity of chronic back pain and depression in Germany: Results from the GEDA study, 2009 and 2010" Z Evid Fortbild Qual Gesundhwes, vol. 137-138, pp. 62-68, 2018.
    @article{Martini.2018, abstract = {BACKGROUND: Depression and chronic back pain are two common disabling diseases. Studies suggest an association of both conditions. We aimed to determine sex- and age-specific prevalences of depression, chronic back pain and the combination of both. Furthermore, influencing factors and resulting consequences were analyzed. METHODS: Data was derived by pooling two representative cross-sectional telephone surveys {\textquotedbl}German Health Update (GEDA){\textquotedbl} 2009 and 2010 including 43,312 adults. Self-reported physician-diagnosed chronic somatic diseases including diagnosed depression and chronic back pain in the past 12 months were assessed. Age- and sex-specific prevalence was calculated. Logistic regression was used to examine their association and identify influencing factors. Sick days, missed workdays and doctor visits were compared for single disease vs. comorbidity. RESULTS: 12-month prevalence for diagnosed depression was 6.7 {\%},
      for chronic back pain 21.1 {\%},
      and the comorbidity of both was 3.0 {\%}. An association of depression and chronic back pain was found for both sexes and all age groups. The characteristics {\textquotedbl}female sex{\textquotedbl},
      {\textquotedbl}being 50-64 years of age{\textquotedbl},
      {\textquotedbl}low socioeconomic status{\textquotedbl} and {\textquotedbl}low social support{\textquotedbl} increased the likelihood of comorbid depression and chronic back pain. Comorbid depression and chronic back pain increased the number of sick days, missed workdays and doctor visits significantly. CONCLUSION: The results show a strong association of depression and chronic back pain. The direction of association cannot be determined due to the cross-sectional design of the study. Identifying patients at risk for comorbid depression and chronic back pain early on might improve treatment and reduce the economic impact.},
      author = {Martini, Luiza and Hoffmann, Falk},
      year = {2018},
      title = {Comorbidity of chronic back pain and depression in Germany: Results from the GEDA study, 2009 and 2010},
      keywords = {*Back Pain/epidemiology;*Depression/epidemiology;Adult;Aged;Befragung;chronic back pain;chronische Ruckenschmerzen;Comorbidity;Cross-Sectional Studies;Depression;Female;Germany/epidemiology;Health services research;Humans;Komorbiditat;Male;Middle Aged;survey;Versorgungsforschung},
      pages = {62--68},
      volume = {137-138},
      issn = {1865-9217},
      journal = {Z Evid Fortbild Qual Gesundhwes},
      doi = {10.1016/j.zefq.2018.10.003},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30415830} }
  • [article] bibtex
    A. Postler, A. Luque Ramos, J. Goronzy, K. P. Gunther, T. Lange, J. Schmitt, A. Zink, und F. Hoffmann, "Prevalence and treatment of hip and knee osteoarthritis in people aged 60 years or older in Germany: an analysis based on health insurance claims data" Clin Interv Aging, vol. 13, pp. 2339-2349, 2018.
    @article{Postler.2018, abstract = {Objective: Osteoarthritis (OA) is highly prevalent throughout the world, especially in the elderly population, and is strongly associated with patients' frailty. However, little is known about the prevalence and treatment of OA in elderly patients in routine clinical care in Germany. Materials and methods: As a part of Linking Patient-Reported Outcomes with CLAIms Data for Health Services Research in Rheumatology (PROCLAIR), a cross-sectional study using claims data from a large Germany statutory health insurance (BARMER) was conducted. We included people aged 60 years or older and assessed the prevalence of OA of the hip or knee, defined as having outpatient diagnoses (ICD: M16 or M17) in at least two quarters of 2014. The use of conservative treatment, including analgesics and physical therapy, and total joint replacement was studied. Analyses were stratified by age, sex, comorbidities, and level of care dependency defined by social law. Results: A total of 595,754 patients (mean age: 74.9 years; 69.8{\%} female) were diagnosed with OA (21.8{\%}), with the highest prevalence in those between 80 and 89 years (31.0{\%}) and in females compared to males (23.9{\%} vs 18.3{\%}). Prevalence decreased with increasing level of care dependency from 30.5{\%} in patients with a low level (0/1) to 18.7{\%} in the highest level of care dependency. A total of 63.4{\%} of the patients with OA received analgesics, with higher use with increasing age. Physical therapy was prescribed to 43.1{\%} of the patients, but use decreased with age. In all, 5.3{\%} of the patients received total joint replacement in 2014. Conclusion: The lower frequency of coded OA with increasing level of care dependency may reflect underdiagnosis, and patients with many other medical problems seem to be at risk for inadequate recognition and treatment of their OA.},
      author = {Postler, Anne and {Luque Ramos},
      A. and Goronzy, Jens and Gunther, K. P. and Lange, Toni and Schmitt, J. and Zink, Angela and Hoffmann, Falk},
      year = {2018},
      title = {Prevalence and treatment of hip and knee osteoarthritis in people aged 60 years or older in Germany: an analysis based on health insurance claims data},
      keywords = {Administrative Claims, Healthcare;Age Factors;Aged;Aged, 80 and over;analgesics;Analgesics/therapeutic use;Arthroplasty, Replacement, Hip/statistics {\&} numerical data;Arthroplasty, Replacement, Knee/statistics {\&} numerical data;Cross-Sectional Studies;Female;frail elderly;Germany/epidemiology;Health services research;Home Care Services/statistics {\&} numerical data;Humans;Insurance, Health;investigator-initiated research from Novartis, ALK, Sanofi, Pfizer, Wyeth, and;Male;Middle Aged;MSD. The other authors have no commercial association that might pose a conflict;of interest in connection with the submitted article.;Osteoarthritis;Osteoarthritis, Hip/*epidemiology/*therapy;Osteoarthritis, Knee/*epidemiology/*therapy;outside the submitted work. JS has received institutional funding of;Physical Therapy Modalities/statistics {\&} numerical data;Prevalence;Sex Factors;total joint replacement},
      pages = {2339--2349},
      volume = {13},
      issn = {1176-9092 (Print) 1176-9092},
      journal = {Clin Interv Aging},
      doi = {10.2147/CIA.S174741},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/30532524},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241868} }
  • [article] bibtex
    O. Spreckelsen, A. Luque Ramos, M. H. Freitag, und F. Hoffmann, "Influenza vaccination rates before and after admission to nursing homes in Germany" Aging Clinical and Experimental Research, vol. 30, iss. 6, pp. 609-616, 2018.
    @article{Spreckelsen.2018, abstract = {BACKGROUND: Influenza vaccination is highly recommended for nursing home residents. However, it is known that vaccination coverage is low in the general population. AIMS: We aim to find out whether influenza vaccination coverage differs for nursing home residents between the year before and after admission and factors determining the chance to receive vaccination. METHODS: Claims data of the health insurance fund DAK of at least 65-year-olds were used. The proportion of residents with influenza vaccination were compared in the year before and after the admission stratified by several covariates. A multivariate logistic regression analysis was conducted to obtain predictors for influenza vaccination after admission. RESULTS: Vaccination coverage was overall higher in the year after admission (53.0{\%}) than before (38.3{\%}). Differences in vaccination coverage between most covariates evened out after admission. Differences remained for region of residence and number of comorbidities. The strongest predictor for receiving a vaccination after admission was the vaccination status before admission (OR 3.5; 95{\%} CI 3.3-3.6) followed by region and number of comorbidities. DISCUSSION: Overall, vaccination coverage of nursing home residents remains lower than recommended. Doctor-patient contacts whether due to care for comorbidities or as a continuation of the relation over the time of admission to the nursing home seem to assure vaccination for residents. CONCLUSION: Clear and unambiguous evidence of vaccine safety and efficacy for different subgroups within the same age group as well as organizational efforts to increase vaccination within nursing homes would be recommended.},
      author = {Spreckelsen, Ove and {Luque Ramos},
      A. and Freitag, Michael H. and Hoffmann, Falk},
      year = {2018},
      title = {Influenza vaccination rates before and after admission to nursing homes in Germany},
      keywords = {*Nursing Homes;Aged;Aged, 80 and over;Female;General practice;Germany;Humans;Influenza;Influenza Vaccines/*administration {\&} dosage;Influenza, Human/*prevention {\&} control;Insurance, Health;Male;nursing home;Probability;Vaccination;Vaccination/*statistics {\&} numerical data},
      pages = {609--616},
      volume = {30},
      number = {6},
      issn = {1594-0667},
      journal = {Aging Clinical and Experimental Research},
      doi = {10.1007/s40520-017-0825-5} }
  • [article] bibtex
    K. Albrecht, A. Luque Ramos, F. Hoffmann, I. Redeker, und A. Zink, "High prevalence of diabetes in patients with rheumatoid arthritis: results from a questionnaire survey linked to claims data" Rheumatology (Oxford), vol. 57, iss. 2, pp. 329-336, 2018.
    @article{Albrecht.2018, abstract = {Objectives: To investigate the prevalence of diabetes in patients with RA and the impact of diabetes on self-reported outcomes and health care. Methods: RA patients between the ages of 18 and 79 years were randomly selected from a nationwide statutory health insurance fund and were surveyed about rheumatological care and disease burden. Comorbid diabetes (E10-14) was analysed regarding age, sex, BMI and socioeconomic status. Disease burden, comorbidity and prescriptions were compared in RA patients with and without diabetes. Predictors of rheumatological care were identified by multivariate regression. Results: Of the 2535 RA patients, 498 (20{\%}) had diabetes. Diabetes was more frequent in males, in older patients, in patients with a higher BMI and in those with a lower socioeconomic status. All disease outcomes were poorer in RA-diabetes patients and were mainly attributable to a higher BMI. RA-diabetes patients received less DMARDs (40{\%} vs 48{\%}) and had more hospital stays (41{\%} vs 30{\%}) than patients without diabetes (all P {\textless} 0.05). Rates of cardiovascular disease (35{\%} vs 15{\%}), depression (39{\%} vs 26{\%}) and renal failure (23{\%} vs 8{\%}) were higher in RA-diabetes patients (all P {\textless} 0.0001). They were less frequently treated by rheumatology specialists: 57{\%} vs 67{\%}; odds ratio = 0.64 (95{\%} CI: 0.45, 0.92), after controlling for confounders. Conclusion: The prevalence of diabetes in patients with RA is high and is associated with known sociodemographic factors. More than 40{\%} of patients with RA and diabetes were not under rheumatological care even though they reported a high disease burden, were frequently hospitalized and often presented with further comorbidities.},
      author = {Albrecht, Katinka and {Luque Ramos},
      A. and Hoffmann, Falk and Redeker, Imke and Zink, Angela},
      year = {2018},
      title = {High prevalence of diabetes in patients with rheumatoid arthritis: results from a questionnaire survey linked to claims data},
      keywords = {*comorbidities;*diabetes;*health care;*rheumatoid arthritis;Adolescent;Adult;Age Factors;Aged;Antirheumatic Agents/therapeutic use;Arthritis, Rheumatoid/drug therapy/*epidemiology;Body Mass Index;Cardiovascular Diseases/epidemiology/etiology;Comorbidity;Depression/epidemiology/etiology;Diabetes Complications;Diabetes Mellitus/*epidemiology;Female;Health Surveys;Hospitalization/statistics {\&} numerical data;Humans;Insurance, Health;Male;Middle Aged;Odds Ratio;Prevalence;Renal Insufficiency/epidemiology/etiology;Risk Factors;Sex Factors;Social Class;Young Adult},
      pages = {329--336},
      volume = {57},
      number = {2},
      issn = {1462-0332 (Electronic) 1462-0324 (Linking)},
      journal = {Rheumatology (Oxford)},
      doi = {10.1093/rheumatology/kex414},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29121263} }
  • [article] bibtex
    C. Bachmann, B. Gerste, und F. Hoffmann, "Diagnoses of autism spectrum disorders in Germany: Time trends in administrative prevalence and diagnostic stability" Autism, vol. 22, iss. 3, pp. 283-290, 2018.
    @article{Bachmann.2018, abstract = {For Germany, no data on trends in autism spectrum disorder diagnoses are available. The primary aim of this study was to establish the time trends in the administrative prevalence of autism spectrum disorder diagnoses. The second aim was to assess the stability of autism spectrum disorder diagnoses over time. We analysed administrative outpatient data (2006-2012) from a nationwide health insurance fund and calculated the prevalence of autism spectrum disorder diagnoses for each year, stratified by age and sex. Additionally, we studied a cohort with a first-time diagnosis of autism spectrum disorder in 2007 through 2012, investigating the percentage of retained autism spectrum disorder diagnoses. From 2006 to 2012, the prevalence of autism spectrum disorder diagnoses in 0- to 24-year-olds increased from 0.22{\%} to 0.38{\%}. In insurees with a first-time autism spectrum disorder diagnosis in 2007, this diagnosis was carried on in all years through 2012 in 33.0{\%} (The International Classification of Diseases, Tenth Revision diagnoses: F84.0/F84.1/F84.5) and 11.2{\%} (F84.8/F84.9), respectively. In Germany, like in other countries, there has been an increase in the administrative prevalence of autism spectrum disorder diagnoses. Yet, prevalences are still lower than in some other Western countries. The marked percentage of autism spectrum disorder diagnoses which were not retained could indicate a significant portion of autism spectrum disorder misdiagnoses, which might contribute to rising autism spectrum disorder prevalences.},
      author = {Bachmann, C. and Gerste, B. and Hoffmann, Falk},
      year = {2018},
      title = {Diagnoses of autism spectrum disorders in Germany: Time trends in administrative prevalence and diagnostic stability},
      keywords = {*autism spectrum disorders;*diagnosis;*Germany;*health services;*prevalence;*secular trends;Adolescent;Adult;Age Factors;Aged;Autism Spectrum Disorder/*diagnosis/epidemiology;Child;Child, Preschool;Female;Germany/epidemiology;Humans;Infant;Infant, Newborn;Male;Middle Aged;Prevalence;Sex Factors;Young Adult},
      pages = {283--290},
      volume = {22},
      number = {3},
      issn = {1362-3613},
      journal = {Autism},
      doi = {10.1177/1362361316673977},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29671642} }
  • [article] bibtex
    A. Brucksch, F. Hoffmann, und K. Allers, "Age and sex differences in emergency department visits of nursing home residents: a systematic review" BMC Geriatrics, vol. 18, iss. 1, p. 151, 2018.
    @article{Brucksch.2018, abstract = {BACKGROUND: Nursing home residents (NHRs) are often transferred to emergency departments (EDs). A great proportion of ED visits is considered inappropriate. There is evidence that male NHRs are more often hospitalised, but this is less clear for ED visits. It is unclear, which influence age has on ED visits. We aimed to study the epidemiology of ED visits in NHRs focusing on age- and sex-specific differences. METHODS: A systematic review was carried out based on articles found in MEDLINE (via PubMed), CINAHL and Scopus. Articles published on or before Aug 31, 2017 were eligible. Two reviewers independently identified articles for inclusion. The quality of studies was assessed by the Joanna Briggs Institute critical appraisal tool for prevalence studies. RESULTS: Out of 1192 references, we found seven studies meeting our inclusion criteria. Six studies were conducted in the USA or Canada. Overall, 29-62{\%} of NHRs had at least one ED visit over the course of 1 year. Most studies assessing the influence of sex found that male residents visited EDs more frequently. All but one of the five studies with multivariable analyses reported a statistically significant positive association (with odds or rate ratios of 1.05-1.38). All studies assessed the influence of age. There was no clear pattern with some studies showing no association between ED visits and age and other studies reporting decreasing ED visits with increasing age or increasing proportions followed by a decrease in the highest age group. Studies used 85+ or 86+ years as the highest age category. Hospital admission rate ranged from 36.4 to 48.7{\%}. There was no study reporting stratified analyses by age and sex. Only one study reported main diagnoses leading to ED visits stratified by sex. CONCLUSION: Male NHRs visit EDs more often than females, but there is no evidence on reasons. The association with age is unclear. Any future study on acute care of NHRs should assess the influence of age and sex. These studies should include large sample sizes to provide a more differentiated age categorisation. TRIAL REGISTRATION: PROSPERO CRD42017074845 .},
      author = {Brucksch, A. and Hoffmann, Falk and Allers, Katharina},
      year = {2018},
      title = {Age and sex differences in emergency department visits of nursing home residents: a systematic review},
      keywords = {*Age;*ED visit;*Emergency department (ED);*Hospital admission;*Nursing;*Nursing home (NH);*Nursing home resident (NHR);*Nursing Homes;*Sex;Age Factors;Aged;Emergency Service, Hospital/*statistics {\&} numerical data;Female;Hospitalization/*trends;Humans;Male;Sex Factors},
      pages = {151},
      volume = {18},
      number = {1},
      issn = {1471-2318},
      journal = {BMC Geriatrics},
      doi = {10.1186/s12877-018-0848-6},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029412},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29970027} }
  • [article] bibtex
    A. M. Fassmer, O. Spreckelsen, und F. Hoffmann, "Incidence of pneumonia in nursing home residents in Germany: results of a claims data analysis" Epidemiol Infect, vol. 146, iss. 9, pp. 1123-1129, 2018.
    @article{Fassmer.2018, abstract = {Pneumonia is one of the most common infectious diseases with a high mortality, especially in the elderly population. To date, there have been only a few population-based studies dealing with the incidence of pneumonia in nursing homes (NHs). We conducted a cohort study using data from a large German statutory health insurance fund. Between 2010 and 2014, 127 227 NH residents 65 years and older were analysed. For the calculation of incidences per 100 person-years (PY) and 95{\%} confidence intervals (CIs), we assessed the first diagnosis of pneumonia during the time in NH. We compared the rates between sexes, age groups, care levels, and comorbidities and we performed a multivariate Cox regression analysis. The mean age in the cohort was 84.0 years (74.6{\%} female). A total of 19 183 incident cases led to an overall 5-year-incidence of 11.8 per 100 PY (95{\%} CI 11.7-12.0). The incidence in men was substantially higher than in women. Rates were highest in the first month after NH placement. Our study revealed that the incidence of pneumonia is high in German NH residents and especially in males. Due to demographic changes, pneumonia will likely be increasingly relevant in the health care of the elderly and institutionalised population.},
      author = {Fassmer, Alexander Maximilian and Spreckelsen, Ove and Hoffmann, Falk},
      year = {2018},
      title = {Incidence of pneumonia in nursing home residents in Germany: results of a claims data analysis},
      keywords = {*Claims data;*elderly;*Germany;*Homes for the Aged;*incidence;*nursing home;*Nursing Homes;*pneumonia;Aged;Aged, 80 and over;Databases, Factual;Female;Follow-Up Studies;Germany/epidemiology;Humans;incidence;Male;Pneumonia/*epidemiology;Proportional Hazards Models;Sex Factors},
      pages = {1123--1129},
      volume = {146},
      number = {9},
      issn = {1469-4409 (Electronic) 0950-2688 (Linking)},
      journal = {Epidemiol Infect},
      doi = {10.1017/S0950268818000997},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29695311} }
  • [article] bibtex
    J. I. Glitza, F. Müller-von-Aschwege, M. Eichelberg, N. Reiss, T. Schmidt, C. Feldmann, R. Wendl, J. D. Schmitto, und A. Hein, "Advanced telemonitoring of Left Ventricular Assist Device patients for the early detection of thrombosis" Journal of Network and Computer Applications, vol. 118, iss. December 2017, pp. 74-82, 2018.
    @article{Glitza.2018, abstract = {In modern times, advanced heart failure is a serious issue. Due to a shortage of donor hearts, the implantation of ``Left Ventricular Assist Device'' (LVAD) as destination therapy has become a common alternative. The LVAD is a mechanical continuous flow pump. However, there are several LVAD complications e.g. a pump thrombosis as a formation of a blood clot inside the LVAD pump. It can result in pump stoppage and lead to death. In order to ensure the success of thrombolytic therapy, it is important to detect a thrombosis early. Since an increase in LVAD power consumption is one indication for a pump thrombosis, this paper shows three algorithms analyzing the LVAD power. These algorithms test absolute and relative threshold and also consider the circadian fluctuation in LVAD power during the day. For the evaluation, a set of 352 LVAD log files including 7 thromboses was used. Compared to the ``High Power Alarm'', which is a predefined thrombosis alarm of the LVAD controller, these algorithms detect all tested LVAD thrombosis up to 140 h earlier. Nevertheless, the algorithms still cause false alarms ({\textless}5{\%}) in patients without an LVAD thrombosis. To reach an earlier and more precise LVAD thrombosis detection, continuous LVAD monitoring is required. Because the LVAD does not provide an interface, an Electrocardiography (ECG) based approach is tested as an alternative monitoring to acquire LVAD data. The LVAD produces an electromagnetical field, whose signal is visible in the ECG. It is utilized to calculate the LVAD speed of 9 LVAD patients using the Fast Fourier Transform. An accuracy of 99.8{\%} was achieved. As external events also influence the LVAD measurements, changes in body posture on the LVAD is tested. The results show that the amplitude, measured during supine position, is significantly different to the amplitude measured during sitting and standing.},
      author = {Glitza, Jenny Inge and M{\"u}ller-von-Aschwege, Frerk and Eichelberg, Marco and Reiss, Nils and Schmidt, Thomas and Feldmann, Christina and Wendl, Regina and Schmitto, Jan Dieter and Hein, Andreas},
      year = {2018},
      title = {Advanced telemonitoring of Left Ventricular Assist Device patients for the early detection of thrombosis},
      keywords = {ECG;HVAD;Left ventricular assist device;Log Files;Pump thrombosis;Telemonitoring},
      pages = {74--82},
      volume = {118},
      number = {December 2017},
      issn = {1084-8045},
      journal = {Journal of Network and Computer Applications},
      doi = {10.1016/j.jnca.2018.04.011},
      file = {Glitza et al. - 2018 - Advanced telemonitoring of Left Ventricular Assist Device patients for the early detection of thrombosis:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Glitza et al. - 2018 - Advanced telemonitoring of Left Ventricular Assist Device patients for the early detection of thrombosis.pdf:pdf} }
  • [article] bibtex
    K. Jobski, F. Hoffmann, S. Herget-Rosenthal, und M. Dörks, "Use of oral anticoagulants in German nursing home residents: drug use patterns and predictors for treatment choice" Br J Clin Pharmacol, vol. 84, iss. 3, pp. 590-601, 2018.
    @article{Jobski.2018, abstract = {AIMS: Information on utilization of oral anticoagulants (OACs) in nursing homes is scarce. This study aimed to (i) describe OAC use in German nursing home residents, (ii) examine factors influencing whether treatment is initiated with vitamin K antagonists (VKAs) or non-VKA oral anticoagulants (NOACs) and (iii) assess which conditions predict switching to NOAC instead of continuing VKA. METHODS: Using claims data (2010-2014), we studied a cohort of new nursing home residents aged $\geq$65 years receiving OAC. Further, OAC use in patients with atrial fibrillation (AF) was examined over the years. RESULTS: Overall, 16 804 patients (median age: 85 years, 75{\%} female, 44{\%} with renal disease) were included. The majority received phenprocoumon as first OAC (58.0{\%}), followed by rivaroxaban (28.1{\%}). Over the study period, NOAC use increased substantially. Initiating NOAC instead of VKA was predicted by a previous stroke (adjusted odds ratio: 1.76; 95{\%} confidence interval: 1.49-2.08). In contrast, renal disease predicted VKA initiation (0.66; 0.59-0.75) as did the presence of a prosthetic heart valve. Switching from VKA to NOAC was predicted by a stroke (2.55; 2.00-3.24), bleeding events and a recent hospitalization. During 2010-2014, the proportion of AF patients with a CHADS2 score $\geq$2 receiving OAC increased from 27{\%} to 46{\%}. CONCLUSIONS: NOACs are increasingly used in German nursing homes, both for initial anticoagulation but also in VKA pre-treated patients. Switching from VKA to NOAC was substantially influenced by aspects such as intended higher effectiveness and safety but probably also practicability due to less blood monitoring.},
      author = {Jobski, Kathrin and Hoffmann, Falk and Herget-Rosenthal, Stefan and D{\"o}rks, Michael},
      year = {2018},
      title = {Use of oral anticoagulants in German nursing home residents: drug use patterns and predictors for treatment choice},
      keywords = {*anticoagulants;*Drug Utilization;*elderly;Administration, Oral;Aged;Aged, 80 and over;Anticoagulants/*administration {\&} dosage/adverse effects;Atrial Fibrillation/*drug therapy;Cohort Studies;Drug Monitoring/methods;Female;Germany;Hemorrhage/epidemiology;Humans;Kidney Diseases/epidemiology;Male;Nursing Homes/*statistics {\&} numerical data;Phenprocoumon/administration {\&} dosage;Rivaroxaban/administration {\&} dosage;Stroke/prevention {\&} control;Vitamin K/*antagonists {\&} inhibitors},
      pages = {590--601},
      volume = {84},
      number = {3},
      issn = {0306-5251 (Print) 0306-5251},
      journal = {Br J Clin Pharmacol},
      doi = {10.1111/bcp.13474},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809357} }
  • [article] bibtex
    K. Jobski, F. Hoffmann, S. Herget-Rosenthal, und M. Dörks, "Use of oral anticoagulants in German nursing home residents: drug use patterns and predictors for treatment choice" Br J Clin Pharmacol, vol. 84, iss. 3, pp. 590-601, 2018.
    @article{Jobski.2018b, abstract = {AIMS: Information on utilization of oral anticoagulants (OACs) in nursing homes is scarce. This study aimed to (i) describe OAC use in German nursing home residents, (ii) examine factors influencing whether treatment is initiated with vitamin K antagonists (VKAs) or non-VKA oral anticoagulants (NOACs) and (iii) assess which conditions predict switching to NOAC instead of continuing VKA. METHODS: Using claims data (2010-2014), we studied a cohort of new nursing home residents aged $\geq$65 years receiving OAC. Further, OAC use in patients with atrial fibrillation (AF) was examined over the years. RESULTS: Overall, 16 804 patients (median age: 85 years, 75{\%} female, 44{\%} with renal disease) were included. The majority received phenprocoumon as first OAC (58.0{\%}), followed by rivaroxaban (28.1{\%}). Over the study period, NOAC use increased substantially. Initiating NOAC instead of VKA was predicted by a previous stroke (adjusted odds ratio: 1.76; 95{\%} confidence interval: 1.49-2.08). In contrast, renal disease predicted VKA initiation (0.66; 0.59-0.75) as did the presence of a prosthetic heart valve. Switching from VKA to NOAC was predicted by a stroke (2.55; 2.00-3.24), bleeding events and a recent hospitalization. During 2010-2014, the proportion of AF patients with a CHADS2 score $\geq$2 receiving OAC increased from 27{\%} to 46{\%}. CONCLUSIONS: NOACs are increasingly used in German nursing homes, both for initial anticoagulation but also in VKA pre-treated patients. Switching from VKA to NOAC was substantially influenced by aspects such as intended higher effectiveness and safety but probably also practicability due to less blood monitoring.},
      author = {Jobski, Kathrin and Hoffmann, Falk and Herget-Rosenthal, Stefan and D{\"o}rks, Michael},
      year = {2018},
      title = {Use of oral anticoagulants in German nursing home residents: drug use patterns and predictors for treatment choice},
      keywords = {*anticoagulants;*Drug Utilization;*elderly;Administration, Oral;Aged;Aged, 80 and over;Anticoagulants/*administration {\&} dosage/adverse effects;Atrial Fibrillation/*drug therapy;Cohort Studies;Drug Monitoring/methods;Female;Germany;Hemorrhage/epidemiology;Humans;Kidney Diseases/epidemiology;Male;Nursing Homes/*statistics {\&} numerical data;Phenprocoumon/administration {\&} dosage;Rivaroxaban/administration {\&} dosage;Stroke/prevention {\&} control;Vitamin K/*antagonists {\&} inhibitors},
      pages = {590--601},
      volume = {84},
      number = {3},
      issn = {0306-5251 (Print) 0306-5251},
      journal = {Br J Clin Pharmacol},
      doi = {10.1111/bcp.13474},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809357} }
  • [article] bibtex
    J. M. Just, L. Bingener, M. Bleckwenn, R. Schnakenberg, und K. Weckbecker, "Risk of opioid misuse in chronic non-cancer pain in primary care patients - a cross sectional study" BMC Fam Pract, vol. 19, iss. 1, p. 92, 2018.
    @article{Just.2018, abstract = {BACKGROUND: Efforts to improve treatment of pain using opioids have to adequately take into account their therapeutic shortcomings which involve addictiveness. While there are no signs of an {\textquotedbl}opioid epidemic{\textquotedbl} in Germany similar to that in the US, there is little data on the prevalence of prescription opioid misuse and addiction. Therefore, our objective was to screen primary care patients on long-term opioid therapy for signs of misuse of prescription opioids. METHODS: We recruited 15 GPs practices and asked all patients on long-term opioid therapy ({\textgreater} 6 months) to fill out a questionnaire including the {\textquotedbl}Current Opioid Misuse Measure{\textquotedbl} (COMM(R)), a self-report questionnaire. Patients with a malignant disease were excluded. RESULTS: N = 91 patients participated in the study (response rate: 75.2{\%}). A third (31.5{\%}) showed a positive COMM(R) - Score which represents a high risk of aberrant drug behaviour. A positive COMM(R) - Score showed a statistically significant correlation with a lifetime diagnosis of depression and neck pain. CONCLUSIONS: While Germany does not face an {\textquotedbl}opioid eoidemic{\textquotedbl},
      addictiveness of opioids should be considered when using them in chronic non-tumor pain. In our study population, almost every third patient was at risk and should therefore be followed up closely. Co-prevalence of depression is a significant issue and should always be screened for in patients with chronic pain, especially thus with aberrant drug behaviour.},
      author = {Just, J. M. and Bingener, L. and Bleckwenn, Markus and Schnakenberg, Rieke and Weckbecker, Klaus},
      year = {2018},
      title = {Risk of opioid misuse in chronic non-cancer pain in primary care patients - a cross sectional study},
      keywords = {*Addiction;*Analgesics, Opioid/adverse effects/therapeutic use;*Chronic Pain/drug therapy/epidemiology;*Depression/diagnosis/epidemiology;*Misuse;*Opioid;*Opioid-Related Disorders/etiology/prevention {\&} control;*Prescription Drug Misuse/adverse effects/prevention {\&} control/statistics {\&};*Prescription drugs;*prevalence;*Primary Health Care/methods/statistics {\&} numerical data;Female;Germany/epidemiology;Humans;Male;Middle Aged;Needs Assessment;numerical data;Risk Adjustment/methods;Risk Factors;Self Report;Surveys and Questionnaires},
      pages = {92},
      volume = {19},
      number = {1},
      issn = {1471-2296},
      journal = {BMC Fam Pract},
      doi = {10.1186/s12875-018-0775-9},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29925323},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6011396} }
  • [article] bibtex
    T. Lange, A. Luque Ramos, K. Albrecht, K. Günther, H. Jacobs, J. Schmitt, F. Hoffmann, J. Goronzy, und A. Postler, "[Prescription frequency of physical therapy and analgesics before total hip and knee arthroplasy : An epidemiological analysis of routine health care data from Germany]" Orthopade, vol. 47, iss. 12, pp. 1018-1026, 2018.
    @article{Lange.2018, abstract = {BACKGROUND: Osteoarthritis of the hip or knee joint is a~widespread disease with a~strong influence on the quality of life. At present, the extent of conservative treatment with physical therapies and analgesics before the use of a~total joint arthroplasty (TJA) of the hip or knee is largely unclear in Germany. OBJECTIVES: The aim was to analyze the prescription frequency according to regional and socio-demographic factors. MATERIALS AND METHODS: Based on routine health care data from BARMER insurance, patients who received a~TJA of the hip or knee from 2011 to 2013 were analyzed. Included were consistently insured patients with the main discharge diagnosis of osteoarthritis who did not receive any further TJA for eight quarters before and after replacement. The prescription frequency of physical therapies and analgesics, stratified according to age groups, gender, number of comorbidities and federal state was analyzed. RESULTS: 40,242 persons with hip TJA and 35,652 persons with knee TJA were included. In the year prior to surgery, 49.4{\%} of patients (hip TJA: 49.9{\%}; knee TJA: 48.9{\%}) received at least one physical therapy and 81.0{\%} were prescribed analgesics. Regionally, the prescription frequency of physical therapies for hip TJA varied between 35.7{\%} (Bremen) and 70.6{\%} (Saxony) and for knee TJA between 37.6{\%} (Saarland) and 66.9{\%} (Saxony). CONCLUSION: The prescription frequency of physical therapy does not fully correspond to current treatment recommendations. The prescription of physical therapies in the year before the TEP shows regional differences, with fundamentally lower prescription frequencies in the former states of West Germany.},
      author = {Lange, Toni and {Luque Ramos},
      A. and Albrecht, Katinka and G{\"u}nther, Klaus--Peter and Jacobs, Hannes and Schmitt, J. and Hoffmann, Falk and Goronzy, Jens and Postler, Anne},
      year = {2018},
      title = {[Prescription frequency of physical therapy and analgesics before total hip and knee arthroplasy : An epidemiological analysis of routine health care data from Germany]},
      keywords = {Analgesic drugs;Analgesics/*therapeutic use;Arthroplasty, Replacement, Hip/statistics {\&} numerical data;Arthroplasty, Replacement, Knee/statistics {\&} numerical data;Conservative treatment;Demography;Drug Prescriptions/*statistics {\&} numerical data;Female;Germany/epidemiology;Humans;Osteoarthritis;Osteoarthritis, Hip/epidemiology/*therapy;Osteoarthritis, Knee/epidemiology/*therapy;Physical Therapy Modalities/*statistics {\&} numerical data;Prevalence;Quality of Life;total joint replacement},
      pages = {1018--1026},
      volume = {47},
      number = {12},
      issn = {0085-4530},
      journal = {Orthopade},
      originalyear = {Verordnungsh{\"a}ufigkeit physikalischer Therapien und Analgetika vor dem Einsatz einer H{\"u}ft- bzw. Kniegelenks-Endoprothese : Eine versorgungsepidemiologische Analyse basierend auf GKV-Routinedaten aus Deutschland.},
      doi = {10.1007/s00132-018-3629-1} }
  • [article] bibtex
    I. Redeker, F. Hoffmann, J. Callhoff, H. Haibel, J. Sieper, A. Zink, und D. Poddubnyy, "Determinants of psychological well-being in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data" Ann Rheum Dis, vol. 77, iss. 7, pp. 1017-1024, 2018.
    @article{Redeker.2018b, abstract = {OBJECTIVES: The aim of this study was to assess the psychological well-being and to analyse factors associated with depressive symptoms in axial spondyloarthritis (axSpA). METHODS: A stratified random sample of subjects with a diagnosis of axSpA (International Classification of Diseases, Tenth Revision, German Modification M45) was drawn from health insurance data in Germany. These persons received a postal questionnaire on disease-related, psychological and lifestyle factors as well as socioeconomic status. Additional information to verify the axSpA diagnosis was also collected. The psychological well-being was assessed by means of the 5-item WHO Well-Being Index (WHO-5), which is considered a screening tool for depression. The following established cut-offs on the WHO-5 were applied: {\textgreater}50: good well-being, no depressive symptoms; 29-50: mild depressive symptoms; {\textless}/=28: moderate-to-severe depressive symptoms. Information on comorbidities, drug prescriptions and non-pharmacological treatment was retrieved from claims data and linked to the questionnaire data. RESULTS: A total of 1736 persons with a confirmed axSpA diagnosis were included. Using the cut-offs on the WHO-5, 533 persons (31{\%}) were found to have moderate-to-severe depressive symptoms, 479 (28{\%}) had mild depressive symptoms and 724 (42{\%}) had a good well-being. Multivariable logistic regression revealed that higher disease activity, higher level of functional impairment, lower income, self-reported stress and lack of exercise, and younger age represent factors associated with moderate-to-severe depressive symptoms. CONCLUSIONS: The prevalence of depressive symptoms in axSpA subjects is high and associated with disease-related parameters, socioeconomic status and lifestyle factors. These findings highlight the need for the careful evaluation of depressive symptoms as a part of the management strategy for axSpA.},
      author = {Redeker, Imke and Hoffmann, Falk and Callhoff, Johanna and Haibel, Hildrun and Sieper, Joachim and Zink, Angela and Poddubnyy, Denis},
      year = {2018},
      title = {Determinants of psychological well-being in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data},
      keywords = {*axial spondyloarthritis;*depression;*Quality of Life;*well-being;Adult;Age Factors;Aged;Cohort Studies;Depression/*epidemiology/*etiology/physiopathology;Disability Evaluation;Female;Germany;Humans;Logistic Models;Male;Middle Aged;Multivariate Analysis;Patient Reported Outcome Measures;Prognosis;Risk Assessment;Sacroiliac Joint;Severity of Illness Index;Sex Factors;Sickness Impact Profile;Spondylarthritis/*diagnosis/*psychology;Spondylitis, Ankylosing/diagnosis/psychology;Surveys and Questionnaires},
      pages = {1017--1024},
      volume = {77},
      number = {7},
      issn = {0003-4967},
      journal = {Ann Rheum Dis},
      doi = {10.1136/annrheumdis-2017-212629},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029638},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29525776} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    P. Elfert, M. Eichelberg, H. Haab, J. Wojzischke, R. Diekmann, und A. Hein, "An Ambient System for Acquiring and Digitizing Health Parameters Targeting Dietary Counseling for Frailty Patients" in Proc. Zukunft der Pflege, Tagungsband der 1. Clusterkonferenz, Oldenburg, 2018, pp. 217-220.
    @inproceedings{Elfert.2018b, abstract = {With the growing number of people affected by hearing loss, large research and development efforts have been carried to improve the performance of hearing aids. Although these efforts have proven fruitful, e.g., by improving the speech enhancement algorithms, further work is needed to improve the automatic and individualized selection of such algorithms, enhance services provided by the hearing aid acousticians to hearing aid users, and support their work by increasing the connectivity of hearing aids. This paper provides a brief overview of the connectivity features available in modern hearing aids as well as the recent developments in acoustic scenes classifiers before describing an hardware / software architecture designed to exploit advances made in both those fields. This proposed architecture offers support to both hearing aid users and professionals of the hearing aid industry.},
      author = {Elfert, Patrick and Eichelberg, Marco and Haab, Henning and Wojzischke, Julia and Diekmann, Rebecca and Hein, Andreas},
      title = {An Ambient System for Acquiring and Digitizing Health Parameters Targeting Dietary Counseling for Frailty Patients},
      url = {https://srvg03.offis.uni-oldenburg.de/piz/wp-content/uploads/2018/06/Zukunft-der-Pflege-Tagungsband-der-Clusterkonferenz-2018.pdf},
      pages = {217--220},
      publisher = {{BIS-Verlag der Carl von Ossietzky Universit{\"a}t Oldenburg}},
      isbn = {978-3-8142-2367-4},
      editor = {Boll, Susanne and Hein, Andreas and Heuten, Wilko and Wolf-Ostermann, Karin},
      booktitle = {Zukunft der Pflege, Tagungsband der 1. Clusterkonferenz},
      year = {2018},
      address = {Oldenburg},
      file = {Elfert et al. - 2018 - An Ambient System for Acquiring and Digitizing Health Parameters Targeting Dietary Counseling for Frailty Patient:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Elfert et al. - 2018 - An Ambient System for Acquiring and Digitizing Health Parameters Targeting Dietary Counseling for Frailty Patient.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    N. Volkening, A. Unni, S. Becker, J. W. Rieger, S. Fudickar, und A. Hein, "Development of a Mobile Functional Near-infrared Spectroscopy Prototype and its Initial Evaluation" in Proc. Proceedings of the 11th PErvasive Technologies Related to Assistive Environments Conference on - PETRA '18, New York, New York, USA, 2018, pp. 214-221.
    @inproceedings{Volkening.2018b,
      author = {Volkening, Nils and Unni, Anirudh and Becker, Sabeth and Rieger, Jochem W. and Fudickar, Sebastian and Hein, Andreas},
      title = {Development of a Mobile Functional Near-infrared Spectroscopy Prototype and its Initial Evaluation},
      url = {http://dl.acm.org/citation.cfm?doid=3197768.3201534},
      keywords = {accepted;fnirs;full paper;functional near-infrared spectroscopy;is a non-invasive;is used;method for the imaging;mobile fnirs;motor cortical activity;of the central nervous;OFFIS=G-AIT/AHT/CSE;prototype;system;UNIAMT;UNICSE},
      pages = {214--221},
      publisher = {{ACM Press}},
      isbn = {9781450363907},
      booktitle = {Proceedings of the 11th PErvasive Technologies Related to Assistive Environments Conference on - PETRA '18},
      year = {2018},
      address = {New York, New York, USA},
      doi = {10.1145/3197768.3201534},
      file = {Volkening et al. - 2018 - Development of a Mobile Functional Near-infrared Spectroscopy Prototype and its Initial Evaluation:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Volkening et al. - 2018 - Development of a Mobile Functional Near-infrared Spectroscopy Prototype and its Initial Evaluation.pdf:pdf} }
  • [article] bibtex
    K. Albrecht, A. Luque Ramos, J. Callhoff, F. Hoffmann, K. Minden, und A. Zink, "[Outpatient care and disease burden of rheumatoid arthritis : Results of a linkage of claims data and a survey of insured persons]" Z Rheumatol, vol. 77, iss. 2, pp. 102-112, 2018.
    @article{Albrecht.2018b, abstract = {BACKGROUND: Healthcare of patients with rheumatoid arthritis (RA) in Germany has mainly been evaluated in the past in RA cohorts from specialized arthritis centers. This study investigated rheumatological care on a population basis, using claims data from a nationwide statutory health insurance fund (BARMER GEK) in combination with patient-reported outcomes from a questionnaire survey of insured persons with RA. METHODS: Data from insurants aged 18-79 years with M05 (seropositive RA) or M06 (other RA, ICD-10) diagnoses were analyzed concerning diagnostics, medication and prescribing physician. A 31-item questionnaire covering patient reported diagnosis, healthcare utilization and burden of illness was sent to a stratified random sample of 6193 insured persons. Data from the respondents regarding rheumatological care and disease status were evaluated. RESULTS: In 2013 and 2014, a total of 96,921 adults with M05 or M06 diagnosis were insured. The questionnaire was answered by 51{\%} of the sample and of these 81{\%} confirmed the RA diagnosis. RA had been diagnosed by a rheumatologist in 59{\%} of the cases, 70{\%} reported moderate to severe pain and 46{\%} had functional disability. Between at least 40{\%} (claims data) and up to 68{\%} (respondents) were in specialized rheumatological care. Treatment with disease-modifying antirheumatic drugs (DMARDs) was 61{\%} (claims data) and 63{\%} (respondents) in persons in rheumatological care but only 18{\%} outside rheumatological care. CONCLUSION: The results indicate that specialized rheumatological care is required to provide adequate treatment for patients with RA in Germany. Patients with higher age and patients with M06 diagnosis had less drug prescriptions and were less frequently treated by rheumatologists.},
      author = {Albrecht, Katinka and {Luque Ramos},
      A. and Callhoff, Johanna and Hoffmann, Falk and Minden, K. and Zink, Angela},
      year = {2018},
      title = {[Outpatient care and disease burden of rheumatoid arthritis : Results of a linkage of claims data and a survey of insured persons]},
      keywords = {*Antirheumatic Agents/therapeutic use;*Arthritis, Rheumatoid/drug therapy;*Information Storage and Retrieval;Adolescent;Adult;Aged;Ambulatory Care;Diagnostics;Disease burden;Drug treatment;Germany;Health care;Humans;Insurance, Health/statistics {\&} numerical data;Middle Aged;Rheumatoid arthritis;Surveys and Questionnaires;Young Adult},
      pages = {102--112},
      volume = {77},
      number = {2},
      issn = {0340-1855},
      journal = {Z Rheumatol},
      originalyear = {Ambulante Versorgung und Krankheitslast der rheumatoiden Arthritis : Eine Analyse von Abrechnungsdaten und einer Versichertenbefragung.},
      doi = {10.1007/s00393-017-0294-4},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28324149} }
  • [article] bibtex
    S. March, M. Antoni, J. Kieschke, B. Kollhorst, B. Maier, G. Muller, M. Sariyar, M. Schulz, E. Steen, J. Zeidler, und F. Hoffmann, "[Quo Vadis Data Linkage in Germany? An Initial Inventory]" Das Gesundheitswesen, vol. 80, iss. 3, p. e20-e31, 2018.
    @article{March.2018, abstract = {In recent years, linking different data sources, also called data linkage or record linkage, to address scientific questions, is being increasingly used in Germany. However, there are very few published reports and new projects develop the necessary tools independently of each other. Therefore, a team of researchers joined together to exchange their experiences on data linkage and to give suggestions on how linkage could be done for scientists, reviewers as well as members of data privacy boards and ethics committees. It is the aim of this article to assist future projects that want to link German data on an individual level. In addition to the legal framework conditions (data privacy), also examples of types of data linkage, their fields of application und potential pitfalls as well as the methods of preventing them will be described in an application-oriented fashion.},
      author = {March, Stefanie and Antoni, M. and Kieschke, Joachim and Kollhorst, Bianca and Maier, Birga and Muller, G. and Sariyar, M. and Schulz, M. and Steen, Enno-Edzard and Zeidler, J. and Hoffmann, Falk},
      year = {2018},
      title = {[Quo Vadis Data Linkage in Germany? An Initial Inventory]},
      keywords = {*Information Storage and Retrieval;Germany},
      pages = {e20-e31},
      volume = {80},
      number = {3},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Quo vadis Datenlinkage in Deutschland? Eine erste Bestandsaufnahme.},
      doi = {10.1055/s-0043-125070},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29462830} }
  • [article] bibtex
    I. Seeger, A. Luque Ramos, und F. Hoffmann, "[Outpatient emergency treatment of nursing home residents : Analysis of insurance claims data]" Z Gerontol Geriatr, vol. 51, iss. 6, pp. 650-655, 2018.
    @article{Seeger.2018, abstract = {BACKGROUND: Utilization of outpatient emergency services by nursing home residents is increasing; however, out of hours medical care (OOHC) in Germany has not yet been studied. OBJECTIVE: In Bremen the used billing codes enabled a comparison between the use of outpatient emergency care in the year before and the year after admission to a nursing home stratified by emergency departments and OOHC. MATERIAL AND METHODS: In this retrospective cohort study we used insurance claims data of residents in Bremen, who were insured in a large German statutory health insurance (DAK-Gesundheit). We compared the use of emergency care in hospitals or OOHC practices in the year before and the year after admission to a nursing home. The incidence rates of visits, distribution on weekdays and coded diagnoses were investigated. RESULTS: We included 1175 nursing home residents (77{\%} female) with a mean age of 85 years. After admission to a nursing home the incidence rate of visits in the OOHC practices increased from 30.4 up to 63.7 and in emergency departments (ED) from 27.4 up to 50.7 per 100 person years. A total of 59{\%} of all visits in OOHC practices were on weekends. The most common diagnoses in ED were injuries and poisoning (75{\%}) while a wide range of diagnoses were coded in the OOHC practices. CONCLUSION: There is a significant difference between diagnoses in the ED and OOHC practices. More research is needed to assess the appropriateness of care.},
      author = {Seeger, Insa and {Luque Ramos},
      A. and Hoffmann, Falk},
      year = {2018},
      title = {[Outpatient emergency treatment of nursing home residents : Analysis of insurance claims data]},
      keywords = {*Emergency Service, Hospital;*Homes for the Aged;*Nursing Homes;*Outpatients;Aged;Aged, 80 and over;Claims data;Emergency care;Emergency Treatment;Female;Germany;Health services research;Humans;Male;Nursing home residents;Retrospective Studies},
      pages = {650--655},
      volume = {51},
      number = {6},
      issn = {1435-1269 (Electronic) 0948-6704 (Linking)},
      journal = {Z Gerontol Geriatr},
      originalyear = {Ambulante Notfallversorgung von Pflegeheimbewohnern : Auswertung von GKV-Routinedaten.},
      doi = {10.1007/s00391-017-1293-4},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28710646} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    S. Hellmers, T. Kromke, L. Dasenbrock, A. Heinks, J. Bauer, A. Hein, und S. Fudickar, "Stair Climb Power Measurements via Inertial Measurement Units - Towards an Unsupervised Assessment of Strength in Domestic Environments" in Proc. Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies, Funchal, 2018, pp. 39-47.
    @inproceedings{Hellmers.2018, abstract = {In order to initiate interventions at an early stage of functional decline and thus, to extend independent living, the early detection of changes in functional ability is important. The Stair Climb Power Test (SCPT) is a standard test in geriatric assessments for strength as one of the essential components of functional ability. This test is also well suited for regular and frequent power measurements in daily life since the activity of climbing stairs is usually frequently performed. We introduce an automated assessment of the SCPT based on inertial measurement units (IMU) in a study of 83 participants aged 70-87 years. For power evaluations of the lower extremities, the activity of climbing stairs was automatically classified via machine learning and the power was calculated based on the test duration and covered height. Climbing stairs was correctly classified in 93{\%} of the cases. We also achieved a good correlation of the power calculations with the conventional stop watch measurements with a mean deviation of 2.35{\%}. The system's sensitivity to detect the transition towards frailty has been confirmed. Furthermore, we discussed the general suitability of the automated stair climb power algorithm in unsupervised, standardized home-assessments.},
      author = {Hellmers, Sandra and Kromke, Tobias and Dasenbrock, Lena and Heinks, Andrea and Bauer, J{\"u}rgen and Hein, Andreas and Fudickar, Sebastian},
      title = {Stair Climb Power Measurements via Inertial Measurement Units - Towards an Unsupervised Assessment of Strength in Domestic Environments},
      url = {http://www.scitepress.org/DigitalLibrary/Link.aspx?doi=10.5220/0006543900390047},
      keywords = {accepted;full paper;UNIAMT},
      pages = {39--47},
      publisher = {{SCITEPRESS - Science and Technology Publications}},
      isbn = {978-989-758-281-3},
      booktitle = {Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies},
      year = {2018},
      address = {Funchal},
      doi = {10.5220/0006543900390047},
      file = {Hellmers et al. - 2018 - Stair Climb Power Measurements via Inertial Measurement Units - Towards an Unsupervised Assessment of Strength:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2018 - Stair Climb Power Measurements via Inertial Measurement Units - Towards an Unsupervised Assessment of Strength.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    C. Lins, S. M. Müller, M. Pfingsthorn, M. Eichelberg, A. Gerka, und A. Hein, "Unsupervised Temporal Segmentation of Skeletal Motion Data using Joint Distance Representation" in Proc. Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies, Funchal, 2018, pp. 478-485.
    @inproceedings{Lins.2018, abstract = {In this paper, we present an online method for the unsupervised segmentation of skeletal motion capture data for the assessment of unfavorable or harmful postures in the context of musculoskeletal disorders. The long-time motion capture data is segmented into short motion sequences using joint distances of the captured skeleton. We use the difference between joint distance matrices to detect variances in motion dynamics in which the motion is separated into either a dynamic motion or a static posture. Then, the static posture can be evaluated using well-known posture assessment methods such as the Ovako Working postures Analysing System (OWAS) to derive risk factors for musculoskeletal disorders. The algorithm works in real-time so that it can be incorporated in live warning systems for unfavorable or harmful postures. We evaluated the segmentation algorithm by comparing it with results from state-of-the-art offline motion segmentation algorithms as gold standard. Results show that the algorithm approaches the performance of state-of-the-art offline segmentation algorithms.},
      author = {Lins, Christian and M{\"u}ller, Sebastian Matthias and Pfingsthorn, Max and Eichelberg, Marco and Gerka, Alexander and Hein, Andreas},
      title = {Unsupervised Temporal Segmentation of Skeletal Motion Data using Joint Distance Representation},
      url = {http://www.scitepress.org/DigitalLibrary/Link.aspx?doi=10.5220/0006598904780485},
      keywords = {capture data for;Ergonomics Assessment;human motion analysis;in this paper;joint distance matrices;method for the unsupervised;Musculoskeletal Disorders;segmentation of skeletal motion;temporal segmentation;UNIAMT;UNILLM;we present an online},
      pages = {478--485},
      publisher = {{SCITEPRESS - Science and Technology Publications}},
      isbn = {978-989-758-281-3},
      booktitle = {Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies},
      year = {2018},
      address = {Funchal},
      doi = {10.5220/0006598904780485},
      file = {Lins et al. - 2018 - Unsupervised Temporal Segmentation of Skeletal Motion Data using Joint Distance Representation:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins et al. - 2018 - Unsupervised Temporal Segmentation of Skeletal Motion Data using Joint Distance Representation.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    C. Lins, A. Klausen, S. Fudickar, S. Hellmers, M. Lipprandt, R. Röhrig, und A. Hein, "Determining Cardiopulmonary Resuscitation Parameters with Differential Evolution Optimization of Sinusoidal Curves" in Proc. Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies, Funchal, 2018, pp. 665-670.
    @inproceedings{Lins.2018b, abstract = {In this paper, we present a robust sinusoidal curve fitting method based on the Differential Evolution (DE) algorithm for determining cardiopulmonary resuscitation (CPR) parameters -- naming chest compression fre-quency and depth -- from skeletal motion data. Our implementation uses skeletal data from the RGB-D (RGB + Depth) Kinect v2 sensor and works without putting non-sensor related constraints such as specific view an-gles or distance to the system. Our approach is intended to be part of a robust and easy-to-use feedback system for CPR training, allowing its unsupervised training. We compare the sensitivity of our DE implementation with data recorded by a Laerdal Resusci Anne mannequin. Results show that the frequency of the DE-based CPR is recognized with a variance of $\pm$4.4 bpm (4.1{\%}) in comparison to the reference of the Resusci Anne mannequin.},
      author = {Lins, Christian and Klausen, Andreas and Fudickar, Sebastian and Hellmers, Sandra and Lipprandt, Myriam and R{\"o}hrig, Rainer and Hein, Andreas},
      title = {Determining Cardiopulmonary Resuscitation Parameters with Differential Evolution Optimization of Sinusoidal Curves},
      url = {http://www.scitepress.org/DigitalLibrary/Link.aspx?doi=10.5220/0006732806650670},
      keywords = {Cardiac Massage;CPR Training;Curve Fitting;Evolutionary Algorithm;UNIAMT;UNILLM},
      pages = {665--670},
      publisher = {{SCITEPRESS - Science and Technology Publications}},
      isbn = {978-989-758-281-3},
      booktitle = {Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies},
      year = {2018},
      address = {Funchal},
      doi = {10.5220/0006732806650670},
      file = {Lins et al. - 2018 - Determining Cardiopulmonary Resuscitation Parameters with Differential Evolution Optimization of Sinusoidal Curves:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins et al. - 2018 - Determining Cardiopulmonary Resuscitation Parameters with Differential Evolution Optimization of Sinusoidal Curves.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    S. Hellmers, S. Fudickar, L. Dasenbrock, A. Heinks, J. Bauer, und A. Hein, "A Model-Based Approach for Jump Analyses Regarding Strength and Balance" in Proc. Biomedical Engineering Systems and Technologies, Cham, 2018, pp. 354-375.
    @inproceedings{Hellmers.2018c, abstract = {To identify the functional decline as related to aging, geriatric assessments are an established instrument. Within such assessments, the functional ability is evaluated and consists of the three major components: strength, mobility, and balance. Counter movement jumps (CMJ) are well-suited to test these three essential elements of functional ability within a single assessment item. Since common balance measures have been shown to be significantly prone to algorithmic and technical variations, a robust alternative method is required. Thus, we introduce a model-based approach for balance and strength analyses, where the human lower extremities are modeled as an oscillating system during the phase of landing and recovery after a vertical jump. In the System and Control Technology, a transfer function of an oscillating system is described by a second-order delay element (PT2-element), which is characterized by the parameters natural frequency and damping. We analyze the jumps of 30 participants (70--87 years) regarding their jump phases and the mentioned parameters. A linear correlation between jump power and jump height, which are sensitive indicators of the muscle performance and the strength could be confirmed. While a correlation between jump power and spring constant could be observed, a significant relationship between the balance ability and natural frequency could not be identified.},
      author = {Hellmers, Sandra and Fudickar, Sebastian and Dasenbrock, Lena and Heinks, Andrea and Bauer, J{\"u}rgen and Hein, Andreas},
      title = {A Model-Based Approach for Jump Analyses Regarding Strength and Balance},
      url = {doi.org/10.1007/978-3-319-94806-5_19},
      keywords = {accepted;full paper;UNIAMT},
      pages = {354--375},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-319-94806-5},
      editor = {Peixoto, Nathalia and Silveira, Margarida and {Ali Hesham},
      H. and Maciel, Carlos and {van den Broek},
      Egon},
      booktitle = {Biomedical Engineering Systems and Technologies},
      year = {2018},
      address = {Cham},
      doi = {10.1007/978-3-319-94806-5{\textunderscore }19},
      file = {Hellmers et al. - 2018 - A Model-Based Approach for Jump Analyses Regarding Strength and Balance:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2018 - A Model-Based Approach for Jump Analyses Regarding Strength and Balance.pdf:pdf} }
  • [article] bibtex
    J. Gensichen, M. H. Freitag, T. Neisecke, D. Ammon, J. Breitbart, A. Freytag, K. Bär, O. Scupin, P. Schlattmann, und M. Specht, "Einfluss intersektoraler elektronischer Medikationslisten auf die Arzneimitteltherapiesicherheit-Online ZFA" , 2017.
    @article{Gensichen.2017,
      author = {Gensichen, Jochen and Freitag, Michael H. and Neisecke, Tobias and Ammon, Danny and Breitbart, J{\"o}rg and Freytag, Antje and B{\"a}r, Karl-J{\"u}rgen and Scupin, Olaf and Schlattmann, Peter and Specht, Martin},
      year = {2017},
      title = {Einfluss intersektoraler elektronischer Medikationslisten auf die Arzneimitteltherapiesicherheit-Online ZFA} }
  • [article] bibtex
    H. I. Stecher, T. M. Pollok, D. Strüber, F. Sobotka, und C. S. Herrmann, "Ten minutes of \textgreeka-tACS and ambient illumination independently modulate EEG \textgreeka-power" Frontiers in Human Neuroscience, 2017.
    @article{Stecher.2017,
      author = {Stecher, H. I. and Pollok, T. M. and Str{\"u}ber, D. and Sobotka, F. and Herrmann, Christoph S.},
      year = {2017},
      title = {Ten minutes of \textgreek{a}-tACS and ambient illumination independently modulate EEG \textgreek{a}-power},
      journal = {Frontiers in Human Neuroscience} }
  • [article] bibtex
    C. Guest, F. Sobotka, A. Karavasopoulou, S. Ward, und C. Bantel, "Nurses and opioids: results of a bi-national survey on mental models regarding opioid administration in hospitals" Journal of Pain Research, iss. 2017:10, 2017.
    @article{Guest.2017,
      author = {Guest, C. and Sobotka, F. and Karavasopoulou, A. and Ward, S. and Bantel, Carsten},
      year = {2017},
      title = {Nurses and opioids: results of a bi-national survey on mental models regarding opioid administration in hospitals},
      number = {2017:10},
      journal = {Journal of Pain Research} }
  • [article] bibtex
    E. Spiegel, T. Kneib, und F. Otto-Sobotka, "Generalized additive models with flexible response functions" F. Stat Comput, pp. 1-16, 2017.
    @article{Spiegel.2017,
      author = {Spiegel, Elmar and Kneib, T. and Otto-Sobotka, F.},
      year = {2017},
      title = {Generalized additive models with flexible response functions},
      pages = {1--16},
      journal = {F. Stat Comput} }
  • [book] bibtex
    Lehrbuch Versorgungsforschung: Systematik -- Methodik -- Anwendung (2. vollständig überarbeitete Ausgabe), Pfaff, H., Neugebauer, E. A., Glaeske, G., und Schrappe, M., Eds., Stuttgart: Schattauer, 2017.
    @book{Pfaff.2017, year = {2017},
      title = {Lehrbuch Versorgungsforschung: Systematik -- Methodik -- Anwendung (2. vollst{\"a}ndig {\"u}berarbeitete Ausgabe)},
      address = {Stuttgart},
      publisher = {Schattauer},
      editor = {Pfaff, H. and Neugebauer, E. A. and Glaeske, G. and Schrappe, M.} }
  • [article] bibtex
    Emmanuel René Karl Schneck, Christian Koch, Mara Borgards, Martin Reichert, Andreas Hecker, Christian Heiß, Winfried Padberg, Enrique Alejandre Lafont, Rainer Röhrig, Gabriele Anja Krombach, Markus A. Weigand, Michael Bernhard, und Fritz Christian Roller, "Impact of abdominal follow-up sonography in trauma patients without abdominal parenchymal organ lesion or free intraabdominal fluid in whole-body computed tomography : Nutzen einer abdominellen Verlaufs-Ultraschalluntersuchung bei Traumapatienten ohne Nachweis von Organverletzungen oder freier Flüssigkeit in der initialen Computertomografie" Röfo Stuttgart [u.a.] : Thieme Vol. 189, No. 2 (2017), p. 128-136 189:2<128-136, p. online-ressource, 2017.
    @article{EmmanuelReneKarlSchneck.2017,
      author = {{Emmanuel Ren{\'e} Karl Schneck} and {Christian Koch} and {Mara Borgards} and {Martin Reichert} and {Andreas Hecker} and {Christian Hei{\ss}} and {Winfried Padberg} and {Enrique Alejandre Lafont} and {Rainer R{\"o}hrig} and {Gabriele Anja Krombach} and {Markus A. Weigand} and {Michael Bernhard} and {Fritz Christian Roller}},
      year = {2017},
      title = {Impact of abdominal follow-up sonography in trauma patients without abdominal parenchymal organ lesion or free intraabdominal fluid in whole-body computed tomography : Nutzen einer abdominellen Verlaufs-Ultraschalluntersuchung bei Traumapatienten ohne Nachweis von Organverletzungen oder freier Fl{\"u}ssigkeit in der initialen Computertomografie},
      pages = {Online-Ressource},
      journal = {R{\"o}fo Stuttgart [u.a.] : Thieme Vol. 189, No. 2 (2017), p. 128-136 189:2{\textless}128-136},
      doi = {10.1055/s-0042-120844} }
  • [article] bibtex
    Rainer Röhrig, Falk Hoffmann, und Myriam Lipprandt, "Patientensicherheit ist in einem soziotechnischem System eine gemeinsame Aufgabe" Zeitschrift für Evidenz, Fortbildung und Qualität im Gesundheitswesen : German journal for evidence and quality in health care : ZEFQ Heidelberg : Elsevier, Urban & Fischer Vol. 125 (2017), p. 1-2 125<1-2, p. online-ressource, 2017.
    @article{RainerRohrig.2017,
      author = {{Rainer R{\"o}hrig} and {Falk Hoffmann} and {Myriam Lipprandt}},
      year = {2017},
      title = {Patientensicherheit ist in einem soziotechnischem System eine gemeinsame Aufgabe},
      pages = {Online-Ressource},
      journal = {Zeitschrift f{\"u}r Evidenz, Fortbildung und Qualit{\"a}t im Gesundheitswesen : German journal for evidence and quality in health care : ZEFQ Heidelberg : Elsevier, Urban {\&} Fischer Vol. 125 (2017), p. 1-2 125{\textless}1-2},
      doi = {10.1016/j.zefq.2017.07.002{\$}{\$}Elinktorsrc} }
  • [book] bibtex
    K. Hower, L. Ansmann, P. Saak, und H. Pfaff, Evaluation des Fitkids-Programms zur Kinderorientierung in Drogenberatungsstellen (EVaFit): Ergebnisbericht der Mitarbeiter*innenbefragung und Leitungsbefragung, Universität zu Köln: Veröffentlichungsreihe des Instituts für Medizinsoziologie, Versorgungsforschung und Rehabilitationswissenschaft (IMVR), 2017.
    @book{Hower.2017,
      author = {Hower, Kira and Ansmann, Lena and Saak, Pamela and Pfaff, Holger},
      year = {2017},
      title = {Evaluation des Fitkids-Programms zur Kinderorientierung in Drogenberatungsstellen (EVaFit): Ergebnisbericht der Mitarbeiter*innenbefragung und Leitungsbefragung},
      address = {Universit{\"a}t zu K{\"o}ln},
      publisher = {{Ver{\"o}ffentlichungsreihe des Instituts f{\"u}r Medizinsoziologie, Versorgungsforschung und Rehabilitationswissenschaft (IMVR)}},
      isbn = {2190-8257} }
  • [inproceedings] bibtex
    A. Gerka, C. Lins, C. Lüpkes, und A. Hein, "Zustandserkennung von Beatmungsgeräten durch zentrale Messung des Stromverbrauchs" in Proc. German Medical Science GMS Publishing House, 2017.
    @inproceedings{Gerka.2017,
      author = {Gerka, Alexander and Lins, Christian and L{\"u}pkes, Christian and Hein, Andreas},
      title = {Zustandserkennung von Beatmungsger{\"a}ten durch zentrale Messung des Stromverbrauchs},
      booktitle = {German Medical Science GMS Publishing House},
      year = {2017},
      doi = {10.3205/17dkvf249},
      file = {Gerka et al. - 2017 - Zustandserkennung von Beatmungsgeräten durch zentrale Messung des Stromverbrauchs:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2017 - Zustandserkennung von Beatmungsgeräten durch zentrale Messung des Stromverbrauchs.pdf:pdf} }
  • [proceedings] bibtex
    Arzneimittelversorgung von Pflegeheimbewohnern in DeutschlandDe Gruyter, 2017.
    @proceedings{Dorks.2017, year = {2017},
      title = {Arzneimittelversorgung von Pflegeheimbewohnern in Deutschland},
      volume = {25},
      publisher = {{De Gruyter}},
      isbn = {0944-5587},
      editor = {D{\"o}rks, Michael and Schmiemann, Guido and Hoffmann, Falk} }
  • [article] bibtex
    M. Dörks, F. Hoffmann, und G. Schmiemann, "Versorgung und Arzneimitteltherapiesicherheit von Pflegeheimbewohnern in Deutschland" Internistische Praxis, vol. 57, iss. 4, pp. 693-702, 2017.
    @article{Dorks.2017c,
      author = {D{\"o}rks, Michael and Hoffmann, Falk and Schmiemann, Guido},
      year = {2017},
      title = {Versorgung und Arzneimitteltherapiesicherheit von Pflegeheimbewohnern in Deutschland},
      pages = {693--702},
      volume = {57},
      number = {4},
      journal = {Internistische Praxis} }
  • [article] bibtex
    E. Waldmann, F. Sobotka, und T. Kneib, "Bayesian regularisation in geoadditive expectile regression" F. Stat Comput, vol. 27, iss. 6, pp. 1539-1553, 2017.
    @article{Waldmann.2017,
      author = {Waldmann, Elisabeth and Sobotka, F. and Kneib, T.},
      year = {2017},
      title = {Bayesian regularisation in geoadditive expectile regression},
      pages = {1539--1553},
      volume = {27},
      number = {6},
      journal = {F. Stat Comput} }
  • [book] bibtex
    German Medical Data Sciences: Visions and Bridges: Proceedings of the 62nd Annual Meeting of the German Association of Medical Informatics, Biometry and Epidemiology (gmds e.V.), Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 243.
    @book{Rohrig.2017, year = {2017},
      title = {German Medical Data Sciences: Visions and Bridges: Proceedings of the 62nd Annual Meeting of the German Association of Medical Informatics, Biometry and Epidemiology (gmds e.V.)},
      volume = {243},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich} }
  • S. Fudickar, J. Kiselev, T. Frenken, S. Wegel, S. Dimitrowska, E. Steinhagen-Thiessen, und A. Hein, "Validation of the ambient TUG chair with light barriers and force sensors in a clinical trial" Assistive Technology, 2017.
    @article{Fudickar.2017, abstract = {Introduction To detect functional changes of elderlies at the earliest possible stage, comprehensive measurements are needed to initiate appropriate interventions and avoid physical decline. The established Timed Up{\&}Go (TUG) test takes little time and, due to its standardised and easy to execute manner, can be conducted by elderlies even without clinical guidance regularly at home. Therefore, cheap light-barriers and force sensors are well-suited ambient sensors that could be easily attached to existing (arm-)chairs to measure the TUG duration and report it back to physicians to identify functional decline as early as possible. Methods We validated the sensitivity of these sensors in a clinical trial with 100 elderlies aged 58 to 92 with a mean of 74 ($\pm$6.78) years in comparison to classical stopwatch TUG measures of professional physicians. We further evaluated the accuracy-enhancement when calibrating the algorithm via a mixed linear model. Results With calibration, light barriers achieved an RMSE of 0.83 s compared to 1.90 s without and force sensors of 0.90 s compared to 2.12 s, respectively. Discussion The suitability to measure accurate TUG times with each of both ambient sensors and to measure TUG regularly in the home of elderlies on a regular basis could be confirmed. Abstract Introduction To detect functional changes of elderlies at the earliest possible stage, comprehensive measurements are needed to initiate appropriate interventions and avoid physical decline. The established Timed Up{\&}Go (TUG) test takes little time and, due to its standardised and easy to execute manner, can be conducted by elderlies even without clinical guidance regularly at home. Therefore, cheap light-barriers and force sensors are well-suited ambient sensors that could be easily attached to existing (arm-)chairs to measure the TUG duration and report it back to physicians to identify functional decline as early as possible. Methods We validated the sensitivity of these sensors in a clinical trial with 100 elderlies aged 58 to 92 with a mean of 74 ($\pm$6.78) years in comparison to classical stopwatch TUG measures of professional physicians. We further evaluated the accuracy-enhancement when calibrating the algorithm via a mixed linear model. Results With calibration, light barriers achieved an RMSE of 0.83 s compared to 1.90 s without and force sensors of 0.90 s compared to 2.12 s, respectively. Discussion The suitability to measure accurate TUG times with each of both ambient sensors and to measure TUG regularly in the home of elderlies on a regular basis could be confirmed.},
      author = {Fudickar, Sebastian and Kiselev, J{\"o}rn and Frenken, Thomas and Wegel, Sandra and Dimitrowska, Slavica and Steinhagen-Thiessen, Elisabeth and Hein, Andreas},
      year = {2017},
      title = {Validation of the ambient TUG chair with light barriers and force sensors in a clinical trial},
      url = {http://mc.manuscriptcentral.com/uaty},
      keywords = {Assessment;Falls;Mobility;Older Adults;Unpublished},
      journal = {Assistive Technology},
      file = {Sebastian Fudickar, Jörn Kiselev, Thomas Frenken, Sandra Wegel, Slavica Dimitrowska - 2017 - Validation of the ambient TUG chair with li:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Sebastian Fudickar, Jörn Kiselev, Thomas Frenken, Sandra Wegel, Slavica Dimitrowska - 2017 - Validation of the ambient TUG chair with li.pdf:pdf} }
  • [incollection] bibtex
    F. Hoffmann und G. Glaeske, "Analyse von Routinedaten" in Lehrbuch Versorgungsforschung: Systematik -- Methodik -- Anwendung (2. vollständig überarbeitete Ausgabe), Pfaff, H., Neugebauer, E. A., Glaeske, G., und Schrappe, M., Eds., Stuttgart: Schattauer, 2017, pp. 122-127.
    @incollection{Hoffmann.2017c,
      author = {Hoffmann, Falk and Glaeske, G.},
      title = {Analyse von Routinedaten},
      pages = {122--127},
      publisher = {Schattauer},
      editor = {Pfaff, H. and Neugebauer, E. A. and Glaeske, G. and Schrappe, M.},
      booktitle = {Lehrbuch Versorgungsforschung: Systematik -- Methodik -- Anwendung (2. vollst{\"a}ndig {\"u}berarbeitete Ausgabe)},
      year = {2017},
      address = {Stuttgart} }
  • [inproceedings] bibtex
    P. Elfert, M. Eichelberg, J. Tröger, J. Britz, J. Alexandersson, D. Bieber, J. Bauer, S. Teichmann, L. Kuhn, M. Thielen, J. Sauer, A. Münzberg, N. Rösch, J. Wojzischke, R. Diekmann, und A. Hein, "DiDiER -- Digitized Services in Dietary Counselling for People with Increased Health Risks Related to Malnutrition and Food Allergies" in Proc. 2017 IEEE Symposium on Computers and Communications (ISCC), Heraklion, Greece, 2017, pp. 100-104.
    @inproceedings{Elfert.2017, abstract = {The goal of the DiDiER project is to verifiably improve services in the field of dietary counselling. This will be achieved by digitising information to increase counselling intensity and to improve workflows for the service provider. The project will develop an IT-based support system for dietary counselling, covering two use cases, facilitation and support of the work of nutritionists in ambulatory allergological nutrition counselling and of nutritionists involved in the care of geriatric patients, especially of those with frailty. One of the project's significant features is that the user's sensitive data remain under his or her personal control at all times.},
      author = {Elfert, Patrick and Eichelberg, Marco and Tr{\"o}ger, Johannes and Britz, Jochen and Alexandersson, Jan and Bieber, Daniel and Bauer, J{\"u}rgen and Teichmann, Susanne and Kuhn, Ludwig and Thielen, Martin and Sauer, Janina and M{\"u}nzberg, Alexander and R{\"o}sch, Norbert and Wojzischke, Julia and Diekmann, Rebecca and Hein, Andreas},
      title = {DiDiER -- Digitized Services in Dietary Counselling for People with Increased Health Risks Related to Malnutrition and Food Allergies},
      pages = {100--104},
      booktitle = {2017 IEEE Symposium on Computers and Communications (ISCC)},
      year = {2017},
      address = {Heraklion, Greece},
      file = {Elfert et al. - 2017 - DiDiER – Digitized Services in Dietary Counselling for People with Increased Health Risks Related to Malnutrition:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Elfert et al. - 2017 - DiDiER – Digitized Services in Dietary Counselling for People with Increased Health Risks Related to Malnutrition.pdf:pdf} }
  • [article] bibtex
    C. Bachmann, A. Philipsen, und F. Hoffmann, "In Reply" Deutsches Arzteblatt International, vol. 114, iss. 25, pp. 428-429, 2017.
    @article{Bachmann.2017b,
      author = {Bachmann, C. and Philipsen, A. and Hoffmann, Falk},
      year = {2017},
      title = {In Reply},
      pages = {428--429},
      volume = {114},
      number = {25},
      journal = {Deutsches Arzteblatt International},
      doi = {10.3238/arztebl.2017.0428b},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28683858},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508066} }
  • A. L. Brütt, R. Meister, T. Bernges, S. Moritz, M. Härter, L. Kriston, und F. Kühne, "Patient involvement in a systematic review: Development and pilot evaluation of a patient workshop" Z Evid Fortbild Qual Gesundhwes, vol. 127-128, pp. 56-61, 2017.
    @article{Brutt.2017,
      author = {Br{\"u}tt, Anna Levke and Meister, R. and Bernges, T. and Moritz, S. and H{\"a}rter, Martin and Kriston, L. and K{\"u}hne, F.},
      year = {2017},
      title = {Patient involvement in a systematic review: Development and pilot evaluation of a patient workshop},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/29129591},
      pages = {56--61},
      volume = {127-128},
      issn = {1865-9217},
      journal = {Z Evid Fortbild Qual Gesundhwes},
      doi = {10.1016/j.zefq.2017.07.005} }
  • [article] bibtex
    J. Köberlein-Neu und F. Hoffmann, "Das Stepped Wedge Design: Stufenlos regelbar?" Z Evid Fortbild Qual Gesundhwes, vol. 126, pp. 1-3, 2017.
    @article{KoberleinNeu.2017,
      author = {K{\"o}berlein-Neu, Juliane and Hoffmann, Falk},
      year = {2017},
      title = {Das Stepped Wedge Design: Stufenlos regelbar?},
      keywords = {*Research Design;Cluster Analysis;Germany;Humans;Multicenter Studies as Topic/methods;Pilot Projects;Randomized Controlled Trials as Topic/*methods},
      pages = {1--3},
      volume = {126},
      issn = {1865-9217},
      journal = {Z Evid Fortbild Qual Gesundhwes},
      doi = {10.1016/j.zefq.2017.09.003} }
  • [article] bibtex
    A. Pérez-Fortis, M. J. Schroevers, J. Fleer, P. Alanís-López, M. G. Veloz-Martínez, R. E. Ornelas-Mejorada, R. Sanderman, A. V. Ranchor, und J. J. Sánchez Sosa, "Psychological burden at the time of diagnosis among Mexican breast cancer patients" Psycho-oncology, vol. 26, iss. 1, pp. 133-136, 2017.
    @article{PerezFortis.2017,
      author = {P{\'e}rez-Fortis, Adriana and Schroevers, Maya J. and Fleer, Joke and Alan{\'i}s-L{\'o}pez, Patricia and Veloz-Mart{\'i}nez, Mar{\'i}a Guadalupe and Ornelas-Mejorada, Rosa Elena and Sanderman, Robbert and Ranchor, Adelita V. and {S{\'a}nchez Sosa},
      Juan Jos{\'e}},
      year = {2017},
      title = {Psychological burden at the time of diagnosis among Mexican breast cancer patients},
      pages = {133--136},
      volume = {26},
      number = {1},
      journal = {Psycho-oncology},
      doi = {10.1002/pon.4098},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/26872293} }
  • [article] bibtex
    R. Röhrig, F. Hoffmann, und M. Lipprandt, "Patientensicherheit ist in einem soziotechnischem System eine gemeinsame Aufgabe" Z Evid Fortbild Qual Gesundhwes, vol. 125, pp. 1-2, 2017.
    @article{Rohrig.2017b,
      author = {R{\"o}hrig, Rainer and Hoffmann, Falk and Lipprandt, Myriam},
      year = {2017},
      title = {Patientensicherheit ist in einem soziotechnischem System eine gemeinsame Aufgabe},
      pages = {1--2},
      volume = {125},
      issn = {1865-9217},
      journal = {Z Evid Fortbild Qual Gesundhwes},
      doi = {10.1016/j.zefq.2017.07.002},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28755828} }
  • E. Spiegel, F. Sobotka, und T. Kneib, "Model selection for expectile regression" Electron. J. Statist., vol. 11, iss. 2, pp. 3008-3038, 2017.
    @article{Spiegel.2017b,
      author = {Spiegel, Elmar and Sobotka, F. and Kneib, T.},
      year = {2017},
      title = {Model selection for expectile regression},
      url = {https://projecteuclid.org/euclid.ejs/1502416822},
      pages = {3008--3038},
      volume = {11},
      number = {2},
      journal = {Electron. J. Statist.},
      doi = {10.1214/17-EJS1307} }
  • A. Timmer, J. Peplies, M. Westphal, B. Kaltz, A. Ballauff, M. Claßen, M. W. Laass, und S. Koletzko, "Transition from pediatric to adult medical care--A survey in young persons with inflammatory bowel disease" PLoS One, vol. 12, iss. 5, p. 0177757, 2017.
    @article{Timmer.2017,
      author = {Timmer, Antje and Peplies, Jenny and Westphal, Max and Kaltz, Birgit and Ballauff, Antje and Cla{\ss}en, Martin and Laass, Martin W. and Koletzko, Sibylle},
      year = {2017},
      title = {Transition from pediatric to adult medical care--A survey in young persons with inflammatory bowel disease},
      url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436761/pdf/pone.0177757.pdf},
      pages = {e0177757},
      volume = {12},
      number = {5},
      issn = {1932-6203 (Electronic) 1932-6203 (Linking)},
      journal = {PLoS One} }
  • A. Timmer, R. Stark, J. Peplies, M. Classen, M. W. Laass, und S. Koletzko, "Current health status and medical therapy of patients with pediatric-onset inflammatory bowel disease: a survey-based analysis on 1280 patients aged 10-25 years focusing on differences by age of onset" Eur J Gastroenterol Hepatol, vol. 29, iss. 11, pp. 1276-1283, 2017.
    @article{Timmer.2017b,
      author = {Timmer, Antje and Stark, R. and Peplies, Jenny and Classen, M. and Laass, Martin W. and Koletzko, Sibylle},
      year = {2017},
      title = {Current health status and medical therapy of patients with pediatric-onset inflammatory bowel disease: a survey-based analysis on 1280 patients aged 10-25 years focusing on differences by age of onset},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/28877085},
      pages = {1276--1283},
      volume = {29},
      number = {11},
      journal = {Eur J Gastroenterol Hepatol},
      doi = {10.1097/MEG.0000000000000956} }
  • [inproceedings] bibtex
    A. Gerka, F. Bayer, M. Eichelberg, M. Frenken, und A. Hein, "Ambient Water Usage Sensor for the Identification of Daily Activities" in Proc. Global Internet of Things Summit, 2017, pp. 225-230.
    @inproceedings{Gerka.2017c, abstract = {Dementia patients, like most older adults, preferto live in their own home as long as possible. This requires,however, that they are able to perform activities of daily living(ADL). Therefore, many research projects install different sensorsetups to identify ADLs. Though the water usage correlates withmany ADLs (i.e.: bathing, cooking) only few of these systemsuse water usage sensors. The reason is that there is no waterusage sensor available that is unobtrusive, ambient and precise.In this article, we propose a water usage sensor that is basedon a piezoelectric element that fulfills these requirements. Wedescribe the implementation of the sensor system in a living lab.Additionally, we discuss different features that were extractedfrom the sensor signal and different machine learning algorithmsthat were used to classify the data. Finally, we present the resultsto several tests we performed to determine the accuracy of oursensor system under different environmental conditions.},
      author = {Gerka, Alexander and Bayer, Finn and Eichelberg, Marco and Frenken, Melina and Hein, Andreas},
      title = {Ambient Water Usage Sensor for the Identification of Daily Activities},
      pages = {225--230},
      publisher = {IEEE},
      isbn = {978-1-5090-5873-0},
      booktitle = {Global Internet of Things Summit},
      year = {2017},
      file = {Gerka et al. - 2017 - Ambient Water Usage Sensor for the Identification of Daily Activities:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2017 - Ambient Water Usage Sensor for the Identification of Daily Activities.pdf:pdf} }
  • A. L. Brütt, T. Bernges, J. L. Magaard, Ex In Pilots, und G. Sielaff, "Mitforschen, aber wie? Entwicklung und Evaluation eines Forschungstrainings fur Psychiatrieerfahrene" Psychiatr Prax, vol. 44, iss. 2, pp. 99-104, 2017.
    @article{Brutt.2017b,
      author = {Br{\"u}tt, Anna Levke and Bernges, T. and Magaard, J. L. and {Ex In Pilots} and Sielaff, G.},
      year = {2017},
      title = {Mitforschen, aber wie? Entwicklung und Evaluation eines Forschungstrainings fur Psychiatrieerfahrene},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/26668092},
      pages = {99--104},
      volume = {44},
      number = {2},
      issn = {0303-4259},
      journal = {Psychiatr Prax},
      doi = {10.1055/s-0041-108968} }
  • [article] bibtex
    J. Defosse, M. Schieren, T. Loop, C. Arndt, R. Röhrig, E. Stoelben, C. Ludwig, A. Schleppers, F. Wappler, M. Gerbershagen, und A. Lopez-Pastorini, "Deutsches Thoraxregister -- Implementierung eines etablierten Werkzeugs der perioperativen Versorgungsforschung" Zentralblatt fur Chirurgie, vol. 142, iss. 3, pp. 330-336, 2017.
    @article{Defosse.2017, abstract = {The collection of clinical treatment data in registry databases is an important aspect of health services research. It allows for a critical evaluation of the safety, efficacy and cost-effectiveness of clinical treatment concepts in large patient populations. The findings of registry research represent real-world patients and treatment structures as they are not limited by strict inclusion criteria or unrealistic conditions as applied in prospective clinical trials. The implementation of the German Thorax Registry has enabled the collection and analysis of data on the interdisciplinary care (thoracic surgery, anaesthesiology, intensive care, pain management) of patients undergoing thoracic surgery. Under the auspices of the German Society of Anaesthesiology and Intensive Care Medicine and the German Society of Thoracic Surgery, a registry of the Hospital of the University Witten/Herdecke-Cologne, purely surgical at first, was expanded in close cooperation with the University Hospital of Freiburg. After a comprehensive data protection concept was drafted and a test phase completed, the German Thorax Registry was officially launched in January 2016. Most notably, participating hospitals profit from the registry's {\textquotedbl}benchmarking{\textquotedbl} services. {\textquotedbl}Benchmarking{\textquotedbl},
      i.e. the comparison of treatment quality between different hospitals, enables participants to identify individual profiles, strengths and weaknesses on a nation-wide level and follow their own progress over the course of several years. An online database for data entry and benchmarking is always accessible (www.thoraxregister.de). In October 2016, the spectrum of participants was expanded to include all hospitals performing at least 50 thoracic operations a year. Die Erhebung klinischer Behandlungsdaten in Registerdatenbanken hat seit Jahren einen hohen Stellenwert in der Versorgungsforschung. Hierdurch kann bspw. eine kritische Pr{\"u}fung der Sicherheit, Wirksamkeit und Wirtschaftlichkeit klinischer Behandlungskonzepte an gro{\ss}en Untersuchungskollektiven erfolgen. Die erhobenen Erkenntnisse aus der Registerforschung entsprechen der tats{\"a}chlichen Patientenklientel und dem Versorgungsalltag der teilnehmenden Kliniken. Sie sind nicht durch strenge Einschlusskriterien oder realit{\"a}tsferne Rahmenbedingungen klinischer prospektiver Studien beschr{\"a}nkt. Durch die Implementierung des Deutschen Thoraxregisters wurde erstmalig die M{\"o}glichkeit geschaffen, die interdisziplin{\"a}re Betreuung (Thoraxchirurgie, An{\"a}sthesiologie, Intensivmedizin, Schmerztherapie) von Patienten mit operativen Eingriffen am Thorax ganzheitlich in einer Datenbank zu erfassen und auszuwerten. Unter der Schirmherrschaft der Deutschen Gesellschaft f{\"u}r An{\"a}sthesiologie und Intensivmedizin (DGAI) und der Deutschen Gesellschaft f{\"u}r Thoraxchirurgie (DGT) wurde ein urspr{\"u}nglich rein thoraxchirurgisches Register des Klinikums der Universit{\"a}t Witten/Herdecke-K{\"o}ln in enger Kooperation mit dem Universit{\"a}tsklinikum Freiburg erweitert. Nach Ausarbeitung eines umfangreichen Datenschutzkonzepts und Abschluss der Pilotphase wurde das Deutsche Thoraxregister als erstes perioperatives, interdisziplin{\"a}res Behandlungsregister im Januar 2016 offiziell implementiert. Neben der reinen Registerforschung, profitieren die teilnehmenden Kliniken vor allem durch die {\glqq}benchmarking{\grqq}-Funktionen. Das {\glqq}benchmarking{\grqq},
      also der Vergleich der Behandlungsqualit{\"a}t verschiedener Kliniken, erlaubt es, individuelle Profile, St{\"a}rken und Schw{\"a}chen im nationalen Vergleich zu identifizieren und eigene Fortschritte {\"u}ber mehrere Jahre zu verfolgen. Das Eingabe- und Benchmarkportal ist jederzeit online verf{\"u}gbar (www.thoraxregister.de). Seit Oktober 2016 wurde das Teilnehmerspektrum erweitert, sodass s{\"a}mtliche Kliniken mit mindestens 50 thoraxchirurgischen Eingriffen im Jahr teilnahmeberechtigt sind.},
      author = {Defosse, J{\'e}r{\^o}me and Schieren, Mark and Loop, Torsten and Arndt, Cerstin and R{\"o}hrig, Rainer and Stoelben, Erich and Ludwig, Corinna and Schleppers, Alexander and Wappler, Frank and Gerbershagen, Mark and Lopez-Pastorini, Alberto},
      year = {2017},
      title = {Deutsches Thoraxregister -- Implementierung eines etablierten Werkzeugs der perioperativen Versorgungsforschung},
      pages = {330--336},
      volume = {142},
      number = {3},
      journal = {Zentralblatt fur Chirurgie},
      doi = {10.1055/s-0043-104770},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28641357} }
  • [article] bibtex
    S. Dubler, M. Laun, C. Koch, A. Hecker, S. Weiterer, B. H. Siegler, R. Röhrig, M. A. Weigand, und C. Lichtenstern, "The impact of real life treatment strategies for Candida peritonitis-A retrospective analysis" Mycoses, vol. 60, iss. 7, pp. 440-446, 2017.
    @article{Dubler.2017, abstract = {Candida species are commonly detected isolates from abdominal foci. The question remains as to who would benefit from early empiric treatment in cases of Candida peritonitis. This study collected real-life data on critically ill patients with Candida peritonitis to estimate the relevance of the chosen treatment strategy on the outcome of these patients. One hundred and thirty-seven surgical intensive care unit (ICU) patients with intra-abdominal invasive Candidiasis were included in the study. Fifty-six patients did not get any antifungal agent. Twenty-nine patients were empirically treated, and 52 patients were specifically treated. In the group without, with empiric and with specific antifungal treatment, the 30-day mortality rate was 33.9, 48.3 and 44.2 respectively. Candida albicans was the most frequently found species. Seven patients in the specific treatment group and one patient in the empiric treatment group emerged with candidaemia. Age, leucocyte count, APACHE II Score and acute liver failure were independent predictors of 30-day mortality in patients with Candida peritonitis. Not all patients with Candida peritonitis received antifungal treatment in real clinical practice. Patients with higher morbidity more often got antifungals. Early empirical therapy has not been associated with a better 30-day mortality.},
      author = {Dubler, S. and Laun, M. and Koch, Christian and Hecker, A. and Weiterer, S. and Siegler, B. H. and R{\"o}hrig, Rainer and Weigand, M. A. and Lichtenstern, C.},
      year = {2017},
      title = {The impact of real life treatment strategies for Candida peritonitis-A retrospective analysis},
      pages = {440--446},
      volume = {60},
      number = {7},
      journal = {Mycoses},
      doi = {10.1111/myc.12615},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28370502} }
  • [article] bibtex
    F. Hoffmann und K. Allers, "Variations over time in the effects of age and sex on hospitalization rates before and after admission to a nursing home: A German cohort study" Maturitas, vol. 102, pp. 50-55, 2017.
    @article{Hoffmann.2017d, abstract = {OBJECTIVES: We examined hospitalization rates for nursing home residents before and after their entry to the home, stratified by sex and age. STUDY DESIGN: A cohort study was conducted using data from a large health insurance fund on 127,227 residents aged 65 years and over newly admitted to a nursing home between January 1, 2010, and December 31, 2014. MAIN OUTCOME MEASUREMENTS: We assessed hospitalization rates and proportions being hospitalized in 6-month intervals one year before nursing home placement and up to 5 years thereafter. Multiple Poisson regression models were fitted to calculate relative risks (RR). RESULTS: Mean age was 84.0 years and 74.6{\%} of the cohort were females. Hospitalization rates were 194.4 per 100 person-years (PY) in the 12 months before entry to the nursing home and 120.0 per 100 PY thereafter. Rates were highest immediately before entry in both sexes. The influence of age was most pronounced in the 12-7 months before entry (RR: 2.37 for 65-74 vs. 95+ years) and declined thereafter (1.29-1.38 up to month 24 after entry). In contrast, the influence of sex was greater after entry (RR: 1.13 for males vs. females in the 12-7 months before and 1.23-1.31 up to month 24 after entry). CONCLUSIONS: Hospitalization rates of nursing home residents are much higher in Germany than in other Western countries. We have provided some insight into the influence of age and sex on hospitalization rates, which varied over the period (time before and after entry to the nursing home) analyzed. We urgently recommend that future studies on the hospitalization of residents stratify their analyses by sex, age and period.},
      author = {Hoffmann, Falk and Allers, Katharina},
      year = {2017},
      title = {Variations over time in the effects of age and sex on hospitalization rates before and after admission to a nursing home: A German cohort study},
      keywords = {Age Factors;Aged;Aged, 80 and over;Care dependency;Cohort Studies;Epidemiology;Female;Germany;Germany/epidemiology;Health services research;Hospitalization/*statistics {\&} numerical data;Humans;Male;Nursing homes;Nursing Homes/*statistics {\&} numerical data;Risk;Sex Factors},
      pages = {50--55},
      volume = {102},
      issn = {0378-5122},
      journal = {Maturitas},
      doi = {10.1016/j.maturitas.2017.04.017} }
  • J. L. Magaard, T. Seeralan, H. Schulz, und A. L. Brütt, "Factors associated with help-seeking behaviour among individuals with major depression: A systematic review" PLoS One, vol. 12, iss. 5, p. 0176730, 2017.
    @article{Magaard.2017,
      author = {Magaard, J. L. and Seeralan, T. and Schulz, H. and Br{\"u}tt, Anna Levke},
      year = {2017},
      title = {Factors associated with help-seeking behaviour among individuals with major depression: A systematic review},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/28493904},
      pages = {e0176730},
      volume = {12},
      number = {5},
      issn = {1932-6203 (Electronic) 1932-6203 (Linking)},
      journal = {PLoS One},
      doi = {10.1371/journal.pone.0176730} }
  • J. L. Magaard, H. Schulz, und A. L. Brütt, "What Do Patients Think about the Cause of Their Mental Disorder? A Qualitative and Quantitative Analysis of Causal Beliefs of Mental Disorder in Inpatients in Psychosomatic Rehabilitation" PLoS One, vol. 12, iss. 1, p. 0169387, 2017.
    @article{Magaard.2017b,
      author = {Magaard, J. L. and Schulz, H. and Br{\"u}tt, Anna Levke},
      year = {2017},
      title = {What Do Patients Think about the Cause of Their Mental Disorder? A Qualitative and Quantitative Analysis of Causal Beliefs of Mental Disorder in Inpatients in Psychosomatic Rehabilitation},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/28056066},
      pages = {e0169387},
      volume = {12},
      number = {1},
      issn = {1932-6203 (Electronic) 1932-6203 (Linking)},
      journal = {PLoS One},
      doi = {10.1371/journal.pone.0169387} }
  • [article] bibtex
    T. P. Naziyok, C. Feeken, A. Zeleke, M. Dörks, und R. Röhrig, "Data Collection of Medication - Impact of Autocompletion in eCRFs on Efficiency and Data Quality" Stud Health Technol Inform, vol. 243, pp. 70-74, 2017.
    @article{Naziyok.2017, abstract = {OBJECTIVE: Openclinica Input Completion (OIC) was developed to increase the efficiency to enter drugs in eCRF in OpenClinica{\textless}sup{\textgreater}(R){\textless}/sup{\textgreater}. The aim of the study was to evaluate the impact on efficiency and data quality as well as usability. METHODS: 20 participants were asked to input 15 drugs with the new tool and by hand. RESULTS: The mean input time got decreased from 16:12m to 3:59m. 31 of 300 (10{\%}) of manual entered medication data sets had one or more errors versus 10 of 300 (3,3{\%}) data sets entered with OIC. CONCLUSION: OIC was able to increase efficiency and data quality. We conclude that new additions to the graphical user interface in electronical Case-Report-Form (eCRF) systems should be validated before usage in research projects.},
      author = {Naziyok, Tolga P. and Feeken, C. and Zeleke, Atinkut and D{\"o}rks, Michael and R{\"o}hrig, Rainer},
      year = {2017},
      title = {Data Collection of Medication - Impact of Autocompletion in eCRFs on Efficiency and Data Quality},
      keywords = {*Data Accuracy;*Data Collection;*Pharmaceutical Preparations;Data Accuracy;Data Collection;eCRF;Efficiency;Humans;Organizational Efficiency;Usability;User-Computer Interface},
      pages = {70--74},
      volume = {243},
      issn = {1879-8365 (Electronic) 0926-9630 (Linking)},
      journal = {Stud Health Technol Inform},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28883173} }
  • [article] bibtex
    A. Pérez-Fortis, J. Fleer, J. J. Sánchez-Sosa, M. G. Veloz-Martínez, P. Alanís-López, M. J. Schroevers, und A. V. Ranchor, "Prevalence and factors associated with supportive care needs among newly diagnosed Mexican breast cancer patients" Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, vol. 25, iss. 10, pp. 3273-3280, 2017.
    @article{PerezFortis.2017b, abstract = {PURPOSE Mexican breast cancer patients are generally diagnosed in advanced stages of the disease and often experience delays in cancer treatment delivery. Currently, little is known about these patients' psychological care needs. This study assessed levels and correlates of supportive care needs of Mexican breast cancer patients around the time of cancer diagnosis. METHODS One hundred seventy-three newly diagnosed Mexican breast cancer patients participated in the study. Supportive care needs, anxiety, depression, and patients' sociodemographic and clinical characteristics were assessed. Multiple regression analyses were used to examine factors associated with care needs. RESULTS Up to 44{\%} of patients showed unmet care needs. Health system/information needs were the most prevalent (68{\%}), while physical/daily living needs the least (19{\%}). Level of depressive symptoms was most consistently related to care needs. Patients with higher levels of depressive symptoms had higher psychological (\textgreek{b}~=~0.38), physical/daily living (\textgreek{b}~=~0.43), patient care/support (\textgreek{b}~=~0.17), and additional unmet care needs (\textgreek{b}~=~0.30), than patients with lower levels of depressive symptoms. CONCLUSIONS This study suggests that mainly health system/information needs arise at the time of cancer diagnosis among Mexican breast cancer patients. Patients suffering high levels of depressive symptoms reported the highest levels of unmet needs. Future studies should be conducted to elucidate the care needs throughout the disease trajectory, as such information can inform health care professionals and policy makers and lead to improvements in the organization and provision of health care services for Mexican breast cancer patients.},
      author = {P{\'e}rez-Fortis, Adriana and Fleer, Joke and S{\'a}nchez-Sosa, Juan Jos{\'e} and Veloz-Mart{\'i}nez, Mar{\'i}a Guadalupe and Alan{\'i}s-L{\'o}pez, Patricia and Schroevers, Maya J. and Ranchor, Adelita V.},
      year = {2017},
      title = {Prevalence and factors associated with supportive care needs among newly diagnosed Mexican breast cancer patients},
      pages = {3273--3280},
      volume = {25},
      number = {10},
      journal = {Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer},
      doi = {10.1007/s00520-017-3741-5},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577048},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28516220} }
  • [article] bibtex
    T. Schmidt, N. Reiss, E. Deniz, C. Feldmann, A. Hein, J. D. Hoffmann, J. I. Röbesaat, J. D. Schmitto, D. Willemsen, und F. Müller-von-Aschwege, "Adaptive pump speed algorithms to improve exercise capacity in patients supported with a left-ventricular assist device" Studies in Health Technology and Informatics, vol. 236, pp. 235-240, 2017.
    @article{Schmidt.2017,
      author = {Schmidt, Thomas and Reiss, Nils and Deniz, Ezin and Feldmann, Christina and Hein, Andreas and Hoffmann, Jan Dirk and R{\"o}besaat, Jenny Inge and Schmitto, Jan Dieter and Willemsen, Detlev and M{\"u}ller-von-Aschwege, Frerk},
      year = {2017},
      title = {Adaptive pump speed algorithms to improve exercise capacity in patients supported with a left-ventricular assist device},
      keywords = {Closed loop system;Exercise capacity;Heart failure;Left-ventricular assist device;Quality of Life},
      pages = {235--240},
      volume = {236},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      doi = {10.3233/978-1-61499-759-7-235},
      file = {Schmidt et al. - 2017 - Adaptive pump speed algorithms to improve exercise capacity in patients supported with a left-ventricular assist:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Schmidt et al. - 2017 - Adaptive pump speed algorithms to improve exercise capacity in patients supported with a left-ventricular assist.pdf:pdf} }
  • [article] bibtex
    I. Seeger, P. Rupp, T. P. Naziyok, L. Rölker-Denker, R. Röhrig, und A. Hein, "Ambulante Versorgung in ZNA und Bereitschaftsdienstpraxis : Eine deskriptive Sekundärdatenanalyse in einer ländlichen Klinik" Medizinische Klinik, Intensivmedizin und Notfallmedizin, vol. 112, iss. 6, pp. 510-518, 2017.
    @article{Seeger.2017b, abstract = {BACKGROUND The use of emergency departments in German hospitals has been increasing in recent years. Emergency care provided by primary care services ({\textquotedbl}Bereitschaftsdienstpraxis{\textquotedbl}) or a~hospital emergency departments (EDs) is the subject of current discussions. AIMS The purpose of this study was to determine the reasons that outpatients with lower treatment urgency consult the ED. Further, the effects of the cooperation between primary care services and the ED will be examined. METHODS The study was an exploratory secondary data analysis of data from the hospital information system and a~quality management survey of a basic and standard care clinic in a~rural area. All patients classified as 4 and 5 according to the emergency severity index (ESI), both four weeks before and after the primary care services and ED visit, were included in the study. RESULTS During the two survey periods, a~total of 1565~outpatient cases were treated, of which 962~cases (61{\%}) were triaged ESI~4 or 5. Of these patients, 324 were surveyed (34{\%}). Overall, 276~cases (85{\%}) visited the ED without contacting a physician beforehand, 161 of the cases (50{\%}) reported an emergency as the reason. In 126~cases (39{\%}) the symptoms lasted more than one day. One-third of all outpatient admissions (537~cases, 34{\%}) visited the ED during the opening hours of the general practitioner. DISCUSSION More than 80{\%} of the surviving cases visited the ED without physician contact beforehand. The most common reason for attending the ED was, {\textquotedbl}It is an emergency.{\textquotedbl} The targeted control of the patients by integrating the primary care service into the ED does not lead to an increased number of cases in the primary care service, but to a~subjective relief of the ED staff.},
      author = {Seeger, Insa and Rupp, P. and Naziyok, Tolga P. and R{\"o}lker-Denker, Lars and R{\"o}hrig, Rainer and Hein, Andreas},
      year = {2017},
      title = {Ambulante Versorgung in ZNA und Bereitschaftsdienstpraxis : Eine deskriptive Sekund{\"a}rdatenanalyse in einer l{\"a}ndlichen Klinik},
      pages = {510--518},
      volume = {112},
      number = {6},
      journal = {Medizinische Klinik, Intensivmedizin und Notfallmedizin},
      doi = {10.1007/s00063-016-0233-1},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27837207} }
  • [incollection] bibtex
    T. Breisig, A. Felscher, A. Hein, M. Hülsken-Giesler, W. Möller, S. Erbschwendtner, C. Fifelski, J. Gilbert, L. M. Glunz, M. Isken, und M. Siemer, "Gesunde Pflegende im Fokus -- Entwicklung von demografiesensiblen, technikunterstützten Arbeitsprozessen in ambulanten Pflegeorganisationen -- Das Projekt ITAGAP" in Neue Ansätze des Arbeits- und Gesundheitsschutzes im Pflege- und Dienstleistungssektor, Fuchs-Frohnhofen, P., Altmann, T., Döring, S., Felscher, A., und Weihrich, M., Eds., Weimar: Bertuch Verlag, 2017, pp. 19-13.
    @incollection{Breisig.2017,
      author = {Breisig, T. and Felscher, Andreas and Hein, Andreas and H{\"u}lsken-Giesler, Manfred and M{\"o}ller, Werner and Erbschwendtner, Sabine and Fifelski, Conrad and Gilbert, Jonathan and Glunz, Lena Marie and Isken, Melvin and Siemer, Maraike},
      title = {Gesunde Pflegende im Fokus -- Entwicklung von demografiesensiblen, technikunterst{\"u}tzten Arbeitsprozessen in ambulanten Pflegeorganisationen -- Das Projekt ITAGAP},
      pages = {19--13},
      publisher = {{Bertuch Verlag}},
      isbn = {978-3-86397-092-5},
      editor = {Fuchs-Frohnhofen, Paul and Altmann, Tobias and D{\"o}ring, Sandra and Felscher, Andreas and Weihrich, Margit},
      booktitle = {Neue Ans{\"a}tze des Arbeits- und Gesundheitsschutzes im Pflege- und Dienstleistungssektor},
      year = {2017},
      address = {Weimar},
      file = {Breisig et al. - 2017 - Gesunde Pflegende im Fokus – Entwicklung von demografiesensiblen, technikunterstützten Arbeitsprozessen in ambu:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Breisig et al. - 2017 - Gesunde Pflegende im Fokus – Entwicklung von demografiesensiblen, technikunterstützten Arbeitsprozessen in ambu.pdf:pdf} }
  • [incollection] bibtex
    T. Fischer und M. H. Freitag, "Obstipation" in Allgemeinmedizin und Familienmedizin, Kochen, M. M., Ed., Stuttgart: Georg Thieme Verlag, 2017, pp. 371-377.
    @incollection{Fischer.2017,
      author = {Fischer, Thomas and Freitag, Michael H.},
      title = {Obstipation},
      pages = {371--377},
      publisher = {{Georg Thieme Verlag}},
      isbn = {9783131413857},
      series = {Duale Reihe},
      editor = {Kochen, Michael M.},
      booktitle = {Allgemeinmedizin und Familienmedizin},
      year = {2017},
      address = {Stuttgart} }
  • [incollection] bibtex
    M. H. Freitag und H. Abholz, "Bauchschmerzen" in Allgemeinmedizin und Familienmedizin, Kochen, M. M., Ed., Stuttgart: Georg Thieme Verlag, 2017, pp. 359-365.
    @incollection{Freitag.2017,
      author = {Freitag, Michael H. and Abholz, Heinz-Harald},
      title = {Bauchschmerzen},
      pages = {359--365},
      publisher = {{Georg Thieme Verlag}},
      isbn = {9783131413857},
      series = {Duale Reihe},
      editor = {Kochen, Michael M.},
      booktitle = {Allgemeinmedizin und Familienmedizin},
      year = {2017},
      address = {Stuttgart} }
  • [incollection] bibtex
    E. Roman-Jäger und M. H. Freitag, "Kinder und Jugendliche in der hausärztlichen Praxis" in Allgemeinmedizin und Familienmedizin, Kochen, M. M., Ed., Stuttgart: Georg Thieme Verlag, 2017, pp. 206-216.
    @incollection{RomanJager.2017,
      author = {Roman-J{\"a}ger, Elke and Freitag, Michael H.},
      title = {Kinder und Jugendliche in der haus{\"a}rztlichen Praxis},
      pages = {206--216},
      publisher = {{Georg Thieme Verlag}},
      isbn = {9783131413857},
      series = {Duale Reihe},
      editor = {Kochen, Michael M.},
      booktitle = {Allgemeinmedizin und Familienmedizin},
      year = {2017},
      address = {Stuttgart} }
  • [inproceedings] bibtex
    J. I. Röbesaat, F. Müller-von-Aschwege, N. Reiss, T. Schmidt, C. Feldmann, E. Deniz, J. D. Schmitto, und A. Hein, "Analysis of LVAD log files for the early detection of pump thrombosis" in Proc. Proceedings - IEEE Symposium on Computers and Communications, 2017, pp. 2-7.
    @inproceedings{Robesaat.2017, abstract = {$\backslash$textcopyright 2017 IEEE. Nowadays, one standard therapy for advanced heart failure is the implantation of left ventricular assist devices (LVAD). The LVAD is a mechanical pump, which supports the heart to pump blood to the rest of the body. However, there are serious complications including pump thrombosis. Pump thrombosis is a formation of blood clot inside the LVAD pump, which can result in pump stop and worst case leads to death. To increase the probability of success in thrombosis treatment, an early diagnosis of pump thrombosis is important. An often mentioned indication for pump thrombosis is an increase in pump current. For this reason, this paper analyzes the log files of LVAD patients. Four algorithms were developed and applied to the measured pump current with the aim to detect an increase in pump current earlier as it is actually done by the physician. The first algorithm incorporated different absolute thresholds. In addition, the second algorithm considered the circadian fluctuation to estimate suitable thresholds. The third and fourth algorithms applied a relative threshold based on the standard deviation of the pump current. The third algorithm applied a standard deviation, which is calculated for each patient and each hours of the day individually. The fourth algorithm used for each patient an individual average standard deviation. This paper shows the results of 5 pump thromboses curves analyzed with the different algorithms each. Using the fourth algorithm, a pump current increase was detected approximately 4 days earlier compared to the 'High Watt' alarm caused by the LVAD controller.},
      author = {R{\"o}besaat, Jenny Inge and M{\"u}ller-von-Aschwege, Frerk and Reiss, Nils and Schmidt, Thomas and Feldmann, Christina and Deniz, Ezin and Schmitto, Jan Dieter and Hein, Andreas},
      title = {Analysis of LVAD log files for the early detection of pump thrombosis},
      keywords = {HVAD;Left ventricular assist device (LVAD);Power increase;Pump thrombosis},
      pages = {2--7},
      isbn = {9781538616291},
      booktitle = {Proceedings - IEEE Symposium on Computers and Communications},
      year = {2017},
      doi = {10.1109/ISCC.2017.8024535},
      file = {Röbesaat et al. - 2017 - Analysis of LVAD log files for the early detection of pump thrombosis:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Röbesaat et al. - 2017 - Analysis of LVAD log files for the early detection of pump thrombosis.pdf:pdf} }
  • [article] bibtex
    K. Allers, M. Dörks, G. Schmiemann, und F. Hoffmann, "Antipsychotic drug use in nursing home residents with and without dementia: keep an eye on the pro re nata medication" Int Clin Psychopharmacol, vol. 32, iss. 4, pp. 213-218, 2017.
    @article{Allers.2017, abstract = {Behavioral and psychological symptoms of dementia often lead to the prescription of antipsychotics, especially in nursing homes, but their use remains controversial. This study aimed to assess antipsychotic drug use in residents with dementia compared with those without dementia. Data were obtained through the cross-sectional 'inappropriate medication in patients with renal insufficiency in nursing homes' (IMREN) study including data from 21 nursing homes. Descriptive statistics were used and factors associated with the prescription of antipsychotics were identified by logistic regression. Overall, 57.5{\%} of the 837 residents had a diagnosis of dementia and 47.0{\%} of residents with dementia and 19.5{\%} of those without dementia received antipsychotics. 35.9{\%} of all antipsychotics in residents with dementia were prescribed as pro re nata (PRN) compared with 23.0{\%} for residents without dementia. Typical antipsychotics were prescribed more commonly than atypical ones. The adjusted logistic regression showed a significant association between the prescription of antipsychotics and dementia (odds ratio: 3.58, 95{\%} confidence interval: 2.45-5.25) as well as severe care dependency (odds ratio: 1.68, 95{\%} confidence interval: 1.10-2.55). Despite safety warnings, antipsychotics are still frequently prescribed to residents with dementia. Almost half received antipsychotics and about a third of the antipsychotics are prescribed as PRN. Further studies should assess the use of PRN antipsychotics and guidelines for PRN prescriptions are clearly needed.},
      author = {Allers, Katharina and D{\"o}rks, Michael and Schmiemann, Guido and Hoffmann, Falk},
      year = {2017},
      title = {Antipsychotic drug use in nursing home residents with and without dementia: keep an eye on the pro re nata medication},
      keywords = {Aged;Aged, 80 and over;Antipsychotic Agents/adverse effects/*therapeutic use;Cross-Sectional Studies;Dementia/*drug therapy/epidemiology/psychology;Drug Prescriptions/*standards;Drug Utilization/*standards/trends;Female;Humans;Male;Nursing Homes/*standards/trends},
      pages = {213--218},
      volume = {32},
      number = {4},
      issn = {0268-1315},
      journal = {Int Clin Psychopharmacol},
      doi = {10.1097/yic.0000000000000173} }
  • [article] bibtex
    C. Bachmann, L. P. Wijlaars, L. J. Kalverdijk, M. Burcu, G. Glaeske, C. C. M. Schuiling-Veninga, F. Hoffmann, L. Aagaard, und J. M. Zito, "Trends in ADHD medication use in children and adolescents in five western countries, 2005-2012" Eur Neuropsychopharmacol, vol. 27, iss. 5, pp. 484-493, 2017.
    @article{Bachmann.2017, abstract = {Over the last two decades, the use of ADHD medication in US youth has markedly increased. However, less is known about ADHD medication use among European children and adolescents. A repeated cross-sectional design was applied to national or regional data extracts from Denmark, Germany, the Netherlands, the United Kingdom (UK) and the United States (US) for calendar years 2005/2006-2012. The prevalence of ADHD medication use was assessed, stratified by age and sex. Furthermore, the most commonly prescribed ADHD medications were assessed. ADHD medication use prevalence increased from 1.8{\%} to 3.9{\%} in the Netherlands cohort (relative increase: +111.9{\%}), from 3.3{\%} to 3.7{\%} in the US cohort (+10.7{\%}), from 1.3{\%} to 2.2{\%} in the German cohort (+62.4{\%}), from 0.4{\%} to 1.5{\%} in the Danish cohort (+302.7{\%}), and from 0.3{\%} to 0.5{\%} in the UK cohort (+56.6{\%}). ADHD medication use was highest in 10-14-year olds, peaking in the Netherlands (7.1{\%}) and the US (8.8{\%}). Methylphenidate use predominated in Europe, whereas in the US amphetamines were nearly as common as methylphenidate. Although there was a substantially greater use of ADHD medications in the US cohort, there was a relatively greater increase in ADHD medication use in youth in the four European countries. ADHD medication use patterns in the US differed markedly from those in western European countries.},
      author = {Bachmann, C. and Wijlaars, L. P. and Kalverdijk, L. J. and Burcu, M. and Glaeske, G. and Schuiling-Veninga, C. C. M. and Hoffmann, Falk and Aagaard, L. and Zito, J. M.},
      year = {2017},
      title = {Trends in ADHD medication use in children and adolescents in five western countries, 2005-2012},
      keywords = {*Adolescent;*Attention Deficit Disorder with Hyperactivity;*Child;*Methylphenidate;*pharmacoepidemiology;Adolescent;Attention Deficit Disorder with Hyperactivity/*drug therapy/*epidemiology;Central Nervous System Stimulants/*therapeutic use;Child;Cohort Studies;Cross-Sectional Studies;Europe/epidemiology;Female;Humans;International Cooperation;Male;Practice Patterns, Physicians'/trends;Prevalence;United States/epidemiology;Young Adult},
      pages = {484--493},
      volume = {27},
      number = {5},
      issn = {0924-977x},
      journal = {Eur Neuropsychopharmacol},
      doi = {10.1016/j.euroneuro.2017.03.002} }
  • [article] bibtex
    C. Bachmann, A. Philipsen, und F. Hoffmann, "ADHD in Germany: Trends in Diagnosis and Pharmacotherapy" Deutsches Arzteblatt International, vol. 114, iss. 9, pp. 141-148, 2017.
    @article{Bachmann.2017c, abstract = {BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) sometimes persists into adulthood. There have been no studies from Germany until the present time on the diagnosis and treatment of ADHD over the course of patients' lives, in particular during the transition from adolescence to early adulthood. METHODS: We used nationwide routine data of the AOK statutory healthinsurance fund to determine the frequency of ADHD diagnoses and prescriptions of medication for ADHD. We additionally analyzed the care of a transition cohort of initially 15-year-old ADHD patients over a period of six years. RESULTS: From 2009 to 2014, the prevalence of a diagnosis of ADHD rose from 5.0{\%} to 6.1{\%} in persons aged 0 to 17 years (with a maximum of 13.9{\%} in 9-year-old boys) and from 0.2{\%} to 0.4{\%} in persons aged 18 to 69 years. The amount of ADHD medication prescribed to adults with ADHD increased over time, while the amount prescribed to children and adolescents fell. Methylphenidate was the most commonly prescribed drug, followed by atomoxetine and lisdexamfetamine. Only 31.2{\%} of the patients in the transition cohort still carried the diagnosis of ADHD at the end of the six-year period, at age 21. The percentage of patients taking ADHD medication in this group fell from 51.8{\%} at age 15 to 6.6{\%} at age 21. CONCLUSION: The administrative prevalence of a diagnosis of ADHD among adults and the degree of medication use for ADHD by adults have risen in recent years. This can be interpreted as an indication of the sensitization of physicians and patients to the possibility of adult ADHD. Nonetheless, the prevalence of diagnosed ADHD remains less than the prevalence revealed by epidemiologic studies. This may indicate that adults with ADHD are currently underdiagnosed and undertreated. The low rate of use of ADHD medications among adolescents with ADHD who are on the verge of adulthood leads us to the question of whether specific transitional concepts need to be developed for this age group.},
      author = {Bachmann, C. and Philipsen, A. and Hoffmann, Falk},
      year = {2017},
      title = {ADHD in Germany: Trends in Diagnosis and Pharmacotherapy},
      keywords = {Adolescent;Adult;Aged;Attention Deficit Disorder with Hyperactivity/diagnosis/*drug;Central Nervous System Stimulants/*therapeutic use;Child;Child, Preschool;Female;Germany/epidemiology;Humans;Infant;Infant, Newborn;Male;Methylphenidate/therapeutic use;Middle Aged;Prevalence;therapy/epidemiology;Young Adult},
      pages = {141--148},
      volume = {114},
      number = {9},
      journal = {Deutsches Arzteblatt International},
      doi = {10.3238/arztebl.2017.0141},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28351466},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378979} }
  • [article] bibtex
    C. Bachmann, L. Aagaard, M. Bernardo, L. Brandt, M. Cartabia, A. Clavenna, A. Coma Fusté, K. Furu, K. Garuoliené, F. Hoffmann, S. Hollingworth, K. F. Huybrechts, L. J. Kalverdijk, K. Kawakami, H. Kieler, T. Kinoshita, S. C. López, J. E. Machado-Alba, M. E. Machado-Duque, M. Mahesri, P. S. Nishtala, D. Piovani, J. Reutfors, L. K. Saastamoinen, I. Sato, C. C. M. Schuiling-Veninga, Y. C. Shyu, D. Siskind, S. Skurtveit, H. Verdoux, L. J. Wang, C. Zara Yahni, H. Zoëga, und D. Taylor, "International trends in clozapine use: a study in 17 countries" Acta Psychiatrica Scandinavica, vol. 136, iss. 1, pp. 37-51, 2017.
    @article{Bachmann.2017d, abstract = {OBJECTIVE: There is some evidence that clozapine is significantly underutilised. Also, clozapine use is thought to vary by country, but so far no international study has assessed trends in clozapine prescribing. Therefore, this study aimed to assess clozapine use trends on an international scale, using standardised criteria for data analysis. METHOD: A repeated cross-sectional design was applied to data extracts (2005-2014) from 17 countries worldwide. RESULTS: In 2014, overall clozapine use prevalence was greatest in Finland (189.2/100 000 persons) and in New Zealand (116.3/100 000), and lowest in the Japanese cohort (0.6/100 000), and in the privately insured US cohort (14.0/100 000). From 2005 to 2014, clozapine use increased in almost all studied countries (relative increase: 7.8-197.2{\%}). In most countries, clozapine use was highest in 40-59-year-olds (range: 0.6/100 000 (Japan) to 344.8/100 000 (Finland)). In youths (10-19 years), clozapine use was highest in Finland (24.7/100 000) and in the publicly insured US cohort (15.5/100 000). CONCLUSION: While clozapine use has increased in most studied countries over recent years, clozapine is still underutilised in many countries, with clozapine utilisation patterns differing significantly between countries. Future research should address the implementation of interventions designed to facilitate increased clozapine utilisation.},
      author = {Bachmann, C. and Aagaard, L. and Bernardo, M. and Brandt, Lena and Cartabia, M. and Clavenna, A. and {Coma Fust{\'e}},
      A. and Furu, K. and Garuolien{\'e},
      K. and Hoffmann, Falk and Hollingworth, S. and Huybrechts, K. F. and Kalverdijk, L. J. and Kawakami, K. and Kieler, H. and Kinoshita, T. and L{\'o}pez, S. C. and Machado-Alba, J. E. and Machado-Duque, M. E. and Mahesri, M. and Nishtala, P. S. and Piovani, D. and Reutfors, Johan and Saastamoinen, L. K. and Sato, I. and Schuiling-Veninga, C. C. M. and Shyu, Y. C. and Siskind, D. and Skurtveit, S. and Verdoux, H. and Wang, L. J. and {Zara Yahni},
      C. and Zo{\"e}ga, H. and Taylor, D.},
      year = {2017},
      title = {International trends in clozapine use: a study in 17 countries},
      keywords = {*clozapine;*pharmacoepidemiology;*psychotic disorders;Adolescent;Adult;Aged;Aged, 80 and over;Antipsychotic Agents/*therapeutic use;Child;Clozapine/*therapeutic use;Cross-Sectional Studies;Drug Prescriptions/*statistics {\&} numerical data;Drug Utilization/*statistics {\&} numerical data/trends;Humans;Middle Aged;Young Adult},
      pages = {37--51},
      volume = {136},
      number = {1},
      issn = {0001-690x},
      journal = {Acta Psychiatrica Scandinavica},
      doi = {10.1111/acps.12742} }
  • [article] bibtex
    M. Dörks, K. Jobski, S. Herget-Rosenthal, und F. Hoffmann, "Mortality and Acute Kidney Injury in Asians With Atrial Fibrillation Treated With Dabigatran or Warfarin" J Am Coll Cardiol, vol. 69, iss. 19, p. 2471, 2017.
    @article{Dorks.2017b,
      author = {D{\"o}rks, Michael and Jobski, Kathrin and Herget-Rosenthal, Stefan and Hoffmann, Falk},
      year = {2017},
      title = {Mortality and Acute Kidney Injury in Asians With Atrial Fibrillation Treated With Dabigatran or Warfarin},
      keywords = {*Acute Kidney Injury;*Atrial Fibrillation;Anticoagulants;Dabigatran;Humans;Warfarin},
      pages = {2471},
      volume = {69},
      number = {19},
      issn = {1558-3597 (Electronic) 0735-1097 (Linking)},
      journal = {J Am Coll Cardiol},
      doi = {10.1016/j.jacc.2017.01.071},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28494991} }
  • [article] bibtex
    Ó. Hálfdánarson, H. Zoëga, L. Aagaard, M. Bernardo, L. Brandt, A. C. Fusté, K. Furu, K. Garuoliené, F. Hoffmann, K. F. Huybrechts, L. J. Kalverdijk, K. Kawakami, H. Kieler, T. Kinoshita, M. Litchfield, S. C. López, J. E. Machado-Alba, M. E. Machado-Duque, M. Mahesri, P. S. Nishtala, S. A. Pearson, J. Reutfors, L. K. Saastamoinen, I. Sato, C. C. M. Schuiling-Veninga, Y. C. Shyu, S. Skurtveit, H. Verdoux, L. J. Wang, C. Z. Yahni, und C. Bachmann, "International trends in antipsychotic use: A study in 16 countries, 2005-2014" Eur Neuropsychopharmacol, vol. 27, iss. 10, pp. 1064-1076, 2017.
    @article{Halfdanarson.2017, abstract = {The objective of this study was to assess international trends in antipsychotic use, using a standardised methodology. A repeated cross-sectional design was applied to data extracts from the years 2005 to 2014 from 16 countries worldwide. During the study period, the overall prevalence of antipsychotic use increased in 10 of the 16 studied countries. In 2014, the overall prevalence of antipsychotic use was highest in Taiwan (78.2/1000 persons), and lowest in Colombia (3.2/1000). In children and adolescents (0-19 years), antipsychotic use ranged from 0.5/1000 (Lithuania) to 30.8/1000 (Taiwan). In adults (20-64 years), the range was 2.8/1000 (Colombia) to 78.9/1000 (publicly insured US population), and in older adults (65+ years), antipsychotic use ranged from 19.0/1000 (Colombia) to 149.0/1000 (Taiwan). Atypical antipsychotic use increased in all populations (range of atypical/typical ratio: 0.7 (Taiwan) to 6.1 (New Zealand, Australia)). Quetiapine, risperidone, and olanzapine were most frequently prescribed. Prevalence and patterns of antipsychotic use varied markedly between countries. In the majority of populations, antipsychotic utilisation and especially the use of atypical antipsychotics increased over time. The high rates of antipsychotic prescriptions in older adults and in youths in some countries merit further investigation and systematic pharmacoepidemiologic monitoring.},
      author = {H{\'a}lfd{\'a}narson, {\'O}. and Zo{\"e}ga, H. and Aagaard, L. and Bernardo, M. and Brandt, Lena and Fust{\'e},
      A. C. and Furu, K. and Garuolien{\'e},
      K. and Hoffmann, Falk and Huybrechts, K. F. and Kalverdijk, L. J. and Kawakami, K. and Kieler, H. and Kinoshita, T. and Litchfield, M. and L{\'o}pez, S. C. and Machado-Alba, J. E. and Machado-Duque, M. E. and Mahesri, M. and Nishtala, P. S. and Pearson, S. A. and Reutfors, Johan and Saastamoinen, L. K. and Sato, I. and Schuiling-Veninga, C. C. M. and Shyu, Y. C. and Skurtveit, S. and Verdoux, H. and Wang, L. J. and Yahni, C. Z. and Bachmann, C.},
      year = {2017},
      title = {International trends in antipsychotic use: A study in 16 countries, 2005-2014},
      keywords = {*Adult;*aged;*Antipsychotic agents;*Internationality;*Minors;*pharmacoepidemiology;Adolescent;Adult;Age Factors;Aged;Antipsychotic Agents/*therapeutic use;Child;Child, Preschool;Cross-Sectional Studies;Drug Therapy/statistics {\&} numerical data/*trends;Humans;Infant;Infant, Newborn;Internationality;Middle Aged;Prevalence;Sex Factors;Young Adult},
      pages = {1064--1076},
      volume = {27},
      number = {10},
      issn = {0924-977x},
      journal = {Eur Neuropsychopharmacol},
      doi = {10.1016/j.euroneuro.2017.07.001} }
  • [article] bibtex
    J. Höfer, F. Hoffmann, und C. Bachmann, "Use of complementary and alternative medicine in children and adolescents with autism spectrum disorder: A systematic review" Autism, vol. 21, iss. 4, pp. 387-402, 2017.
    @article{Hofer.2017, abstract = {Despite limited evidence, complementary and alternative medicine treatments are popular in autism spectrum disorder. The aim of this review was to summarize the available evidence on complementary and alternative medicine use frequency in autism spectrum disorder. A systematic search of three electronic databases was performed. All research studies in English or German reporting data on the frequency of complementary and alternative medicine use in individuals with autism spectrum disorder were included. Two independent reviewers searched the literature, extracted information on study design and results, and assessed study quality using an established quality assessment tool. Twenty studies with a total of 9540 participants were included. The prevalence of any complementary and alternative medicine use ranged from 28{\%} to 95{\%} (median: 54{\%}). Special diets or dietary supplements (including vitamins) were the most frequent complementary and alternative medicine treatments, ranking first in 75{\%} of studies. There was some evidence for a higher prevalence of complementary and alternative medicine use in autism spectrum disorder compared to other psychiatric disorders and the general population. Approximately half of children and adolescents with autism spectrum disorder use complementary and alternative medicine. Doctors should be aware of this and should discuss complementary and alternative medicine use with patients and their carers, especially as the evidence is mixed and some complementary and alternative medicine treatments are potentially harmful.},
      author = {H{\"o}fer, J. and Hoffmann, Falk and Bachmann, C.},
      year = {2017},
      title = {Use of complementary and alternative medicine in children and adolescents with autism spectrum disorder: A systematic review},
      keywords = {*Autism spectrum disorder;*complementary and alternative medicine;*Complementary Therapies/adverse effects/methods/statistics {\&} numerical data;*prevalence;*Systematic review;Adolescent;Age Factors;Autism Spectrum Disorder/*therapy;Child;Female;Humans;Male;Sex Factors},
      pages = {387--402},
      volume = {21},
      number = {4},
      issn = {1362-3613},
      journal = {Autism},
      doi = {10.1177/1362361316646559} }
  • [article] bibtex
    F. Hoffmann und G. Schmiemann, "Influence of age and sex on hospitalization of nursing home residents: A cross-sectional study from Germany" BMC Health Services Research, vol. 17, iss. 1, p. 55, 2017.
    @article{Hoffmann.2017, abstract = {BACKGROUND: Nursing homes residents (NHR) are frequently transferred to hospitals. There is some evidence that male NHR are more often hospitalized than females, but the influence of age is less clear and predictors might differ between sexes. Analyses according to age groups between males and females have only been investigated once and none of the existing studies have conducted multivariate analyses stratified by sex. Aim of this study was to fill this gap. METHODS: We used data of the {\textquotedbl}Inappropriate Medication in patients with REnal insufficiency in Nursing homes{\textquotedbl} (IMREN) study, which was conducted between October 2014 and April 2015 in nursing homes in northwestern Germany (Bremen and Lower Saxony). Anonymised data was obtained by nursing staff of the participating nursing homes. All residents living in the participating care units were included. We assessed whether they were hospitalized at least once during the preceding 12 months. Cluster-adjusted multivariate logistic regression was applied to identify variables associated with hospitalizations. All analyses were stratified by sex. RESULTS: Of 852 residents from 21 nursing homes (mean age 83.5 years; 76.5{\%} females), 43.1{\%} (95{\%} confidence intervals [95{\%} CI]: 35.6-50.5) were hospitalized at least once during the preceding 12 months. This proportion was higher in residents institutionalized within the last 6 months compared to those with a longer length of stay (65.7{\%} vs. 39.5{\%}). Although not statistically significant, males were more often hospitalized than females (52.4{\%} vs. 40.3{\%}) and differences between sexes are particularly remarkable for age, health status and length of stay. In females, the chance of being hospitalized decreased steadily with age (OR: 2.40 [95{\%} CI: 1.24-4.64] and 1.60 [95{\%} CI: 1.05-2.43] for age groups {\textless}75 and 75-84 years compared to 85+ years). On the other hand, males aged 75-84 years had a statistically significant lower chance compared to 85+ years olds (OR: 0.41; 95{\%} CI: 0.19-0.90). CONCLUSIONS: Differences in factors associated with hospitalizations might exist between sexes. We strongly suggest that further studies on hospitalizations of NHR should stratify their analyses by sex.},
      author = {Hoffmann, Falk and Schmiemann, Guido},
      year = {2017},
      title = {Influence of age and sex on hospitalization of nursing home residents: A cross-sectional study from Germany},
      keywords = {*Care dependency;*epidemiology;*Germany;*Health services research;*Nursing Homes;Age Factors;Aged;Aged, 80 and over;Cross-Sectional Studies;Female;Germany;Health Status;Homes for the Aged/*statistics {\&} numerical data;Hospitalization/*statistics {\&} numerical data;Hospitals;Humans;Logistic Models;Male;Nursing Homes/*statistics {\&} numerical data;Sex Factors},
      pages = {55},
      volume = {17},
      number = {1},
      journal = {BMC Health Services Research},
      doi = {10.1186/s12913-017-2008-7},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247821},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28103927} }
  • [article] bibtex
    K. Jobski, J. Höfer, F. Hoffmann, und C. Bachmann, "Use of psychotropic drugs in patients with autism spectrum disorders: a systematic review" Acta Psychiatrica Scandinavica, vol. 135, iss. 1, pp. 8-28, 2017.
    @article{Jobski.2017b, abstract = {OBJECTIVE: The objective of this review was to examine prevalence and patterns of psychopharmacotherapy in individuals with autism spectrum disorder (ASD). METHOD: A systematic literature search in PubMed, CINAHL, and PsycINFO was performed, including articles published up to November 18, 2015. RESULTS: A total of 47 studies (data collection: 1976-2012), encompassing {\textgreater}300~000 individuals with ASD, were included. The prevalence of psychopharmacotherapy ranged from 2.7{\%} to 80{\%} (median (overall): 45.7{\%}; median (children): 41.9{\%}; median (adults): 61.5{\%}), with psychotropic polypharmacy occurring in 5.4-54{\%} (median: 23.0{\%}). Regarding drug classes, antipsychotics were most frequently used, followed by attention-deficit/hyperactivity disorder (ADHD) medication and antidepressants. Both older age and psychiatric comorbidity were associated with higher prevalences of psychopharmacotherapy and psychotropic polypharmacy. There were no time trends in psychopharmacotherapy prevalence observable. CONCLUSION: Despite a lack of pharmacological treatment options for ASD core symptoms, the prevalence of psychopharmacotherapy and polypharmacy in ASD patients is considerable, which is probably due to the treatment of non-core ASD symptoms and psychiatric comorbidities. While there is some evidence for the use of antipsychotics and ADHD medication for these indications, the use of antidepressants should be limited to selected cases.},
      author = {Jobski, Kathrin and H{\"o}fer, J. and Hoffmann, Falk and Bachmann, C.},
      year = {2017},
      title = {Use of psychotropic drugs in patients with autism spectrum disorders: a systematic review},
      keywords = {Adolescent;Autism spectrum disorder;Autism Spectrum Disorder/*drug therapy;Child;drug-therapy;Female;Humans;Male;polypharmacy;Prevalence;psychotropic drugs;Psychotropic Drugs/*classification/*therapeutic use},
      pages = {8--28},
      volume = {135},
      number = {1},
      issn = {0001-690x},
      journal = {Acta Psychiatrica Scandinavica},
      doi = {10.1111/acps.12644} }
  • [article] bibtex
    K. Jobski, N. Schmedt, B. Kollhorst, J. Krappweis, T. Schink, und E. Garbe, "Characteristics and drug use patterns of older antidepressant initiators in Germany" Eur J Clin Pharmacol, vol. 73, iss. 1, pp. 105-113, 2017.
    @article{Jobski.2017d, abstract = {PURPOSE: The purpose of this study was to investigate characteristics, drug use patterns, and predictors for treatment choice in older German patients initiating antidepressant (AD) treatment. METHODS: Using the German Pharmacoepidemiological Research Database, we identified a cohort of AD initiators aged at least 65~years between 2005 and 2011. Potential indications, co-morbidity, and co-medication as well as treatment patterns such as the duration of the first treatment episode were assessed. In addition, a logistic regression model was used to identify independent predictors for initiating treatment with tricyclic ADs (TCAs) compared to selective serotonin reuptake inhibitors (SSRIs). RESULTS: Overall, 508,810 individuals were included in the cohort. About 55~{\%} of patients initiated AD treatment with TCAs, followed by 22~{\%} receiving SSRIs. During the study period, a decrease of treatment initiation with TCAs was observed. Higher age and male sex as well as being diagnosed with depression were highly associated with SSRI treatment, whereas pain and sleeping disorders were strong predictors for initiating TCA treatment. The duration of the first treatment episode was substantially longer in SSRI users compared to TCA initiators (median 119 vs. 43~days). CONCLUSIONS: Potential indications and drug use patterns in older German AD initiators varied substantially for different drug classes and single agents. Given the anticholinergic and sedative properties of TCAs, the frequent use of this drug class though probably related to indications such as pain was remarkable.},
      author = {Jobski, Kathrin and Schmedt, N. and Kollhorst, Bianca and Krappweis, J. and Schink, Tania and Garbe, E.},
      year = {2017},
      title = {Characteristics and drug use patterns of older antidepressant initiators in Germany},
      keywords = {*Antidepressants;*Drug Utilization;*Germany;*Older patients;*Tricyclic antidepressants;Aged;Aged, 80 and over;Antidepressive Agents/classification/*therapeutic use;Depression/*drug therapy;Drug Utilization/statistics {\&} numerical data;Female;Germany;Humans;Male;Practice Patterns, Physicians'},
      pages = {105--113},
      volume = {73},
      number = {1},
      issn = {0031-6970},
      journal = {Eur J Clin Pharmacol},
      doi = {10.1007/s00228-016-2145-7} }
  • [article] bibtex
    L. J. Kalverdijk, C. Bachmann, L. Aagaard, M. Burcu, G. Glaeske, F. Hoffmann, I. Petersen, C. C. M. Schuiling-Veninga, L. P. Wijlaars, und J. M. Zito, "A multi-national comparison of antipsychotic drug use in children and adolescents, 2005-2012" Child Adolesc Psychiatry Ment Health, vol. 11, p. 55, 2017.
    @article{Kalverdijk.2017, abstract = {Over the last decades, an increase in antipsychotic (AP) prescribing and a shift from first-generation antipsychotics (FGA) to second-generation antipsychotics (SGA) among youth have been reported. However, most AP prescriptions for youth are off-label, and there are worrying long-term safety data in youth. The objective of this study was to assess multinational trends in AP use among children and adolescents. A repeated cross-sectional design was applied to cohorts from varied sources from Denmark, Germany, the Netherlands, the United Kingdom (UK) and the United States (US) for calendar years 2005/2006-2012. The annual prevalence of AP use was assessed, stratified by age group, sex and subclass (FGA/SGA). The prevalence of AP use increased from 0.78 to 1.03{\%} in the Netherlands' data, from 0.26 to 0.48{\%} in the Danish cohort, from 0.23 to 0.32{\%} in the German cohort, and from 0.1 to 0.14{\%} in the UK cohort. In the US cohort, AP use decreased from 0.94 to 0.79{\%}. In the US cohort, nearly all ATP dispensings were for SGA, while among the European cohorts the proportion of SGA dispensings grew to nearly 75{\%} of all AP dispensings. With the exception of the Netherlands, AP use prevalence was highest in 15-19~year-olds. So, from 2005/6 to 2012, AP use prevalence increased in all youth cohorts from European countries and decreased in the US cohort. SGA were favoured in all countries' cohorts.},
      author = {Kalverdijk, L. J. and Bachmann, C. and Aagaard, L. and Burcu, M. and Glaeske, G. and Hoffmann, Falk and Petersen, I. and Schuiling-Veninga, C. C. M. and Wijlaars, L. P. and Zito, J. M.},
      year = {2017},
      title = {A multi-national comparison of antipsychotic drug use in children and adolescents, 2005-2012},
      keywords = {Adolescents;Antipsychotic drugs;Atypical;Children;Denmark;Germany;Netherlands;pharmacoepidemiology;Uk;USA},
      pages = {55},
      volume = {11},
      issn = {1753-2000 (Print) 1753-2000},
      journal = {Child Adolesc Psychiatry Ment Health},
      doi = {10.1186/s13034-017-0192-1},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637352} }
  • [article] bibtex
    A. Luque Ramos, C. Ohlmeier, D. Enders, R. Linder, D. Horenkamp-Sonntag, J. H. Prochaska, R. Mikolajczyk, und E. Garbe, "Initiation and duration of dual antiplatelet therapy after inpatient percutaneous coronary intervention with stent implantation in Germany: An electronic healthcare database cohort study" Z Evid Fortbild Qual Gesundhwes, vol. 120, pp. 31-38, 2017.
    @article{LuqueRamos.2017, abstract = {BACKGROUND: Studies assessing the routine outpatient dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) in Germany are scarce. The aim of this study was (i) to investigate the initiation and duration of DAPT after inpatient PCI with stent implantation in Germany, and (ii) to identify factors associated with DAPT discontinuation during the recommended treatment period. METHODS: This retrospective cohort study was based on data from a large German electronic healthcare database of the years 2004 to 2009. The study population comprised four groups of patients with acute coronary syndrome (ACS) or stable angina pectoris undergoing inpatient PCI with either bare metal stent (BMS) or drug eluting stent (DES) implantation between 2005 and 2008. Initiation of outpatient DAPT within a period from 100 days before the PCI to 60 days after the PCI was ascertained. Time until end of treatment was analysed using the Kaplan-Meier method. Factors potentially associated with DAPT discontinuation, like sex, age, cardiovascular comorbidity, contraindications, and other antithrombotic drugs were analysed in a Cox proportional hazard model. RESULTS: The cohort comprised 37,001 patients. Depending on the type of stent and the indication for the PCI, DAPT was initiated in 85 {\%} (ACS/BMS) and 95 {\%} (AP/DES) of all patients. Of those, 12 {\%} (AP/DES) and 64 {\%} (ACS/BMS) discontinued DAPT during the recommended treatment duration. An age of over 80 years (OR 1.2-1.5 compared to patients aged 0-49 years) and the use of phenprocoumon (OR 2.7-5.0 compared to no phenprocoumon) were associated with an increased risk of DAPT discontinuation. CONCLUSIONS: A high proportion of patients with coronary artery disease undergoing inpatient PCI with stent implantation received DAPT. However, DAPT discontinuation during the recommended time span was frequent, particularly in patients suffering from ACS. On the other hand, especially patients with AP and DES were often treated longer than recommended.},
      author = {{Luque Ramos},
      A. and Ohlmeier, C. and Enders, D. and Linder, R. and Horenkamp-Sonntag, Dirk and Prochaska, J. H. and Mikolajczyk, R. and Garbe, E.},
      year = {2017},
      title = {Initiation and duration of dual antiplatelet therapy after inpatient percutaneous coronary intervention with stent implantation in Germany: An electronic healthcare database cohort study},
      keywords = {*Drug-Eluting Stents;*Percutaneous Coronary Intervention/methods;acute coronary syndrome;akutes Koronarsyndrom;antiplatelet drugs;Claims data;coronary artery disease;Deutschland;Germany;Humans;Inpatients;koronare Herzkrankheit;percutaneous coronary intervention;perkutane koronare Intervention;Platelet Aggregation Inhibitors/*therapeutic use;Retrospective Studies;Sekundardaten;Stents;Thrombozytenaggregationshemmer;Time Factors;Treatment Outcome},
      pages = {31--38},
      volume = {120},
      issn = {1865-9217},
      journal = {Z Evid Fortbild Qual Gesundhwes},
      doi = {10.1016/j.zefq.2016.12.007},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28284365} }
  • [article] bibtex
    A. Luque Ramos, F. Hoffmann, K. Albrecht, J. Klotsche, A. Zink, und K. Minden, "Transition to adult rheumatology care is necessary to maintain DMARD therapy in young people with juvenile idiopathic arthritis" Semin Arthritis Rheum, vol. 47, iss. 2, pp. 269-275, 2017.
    @article{LuqueRamos.2017b, abstract = {OBJECTIVE: To evaluate the outpatient health service utilisation of young people (YP) with juvenile idiopathic arthritis (JIA) during transfer from paediatric to adult care in Germany. METHODS: Based on claims data of a large German statutory health fund (BARMER GEK) we conducted a cohort study of 2008-2014. Insured YP with diagnosis of JIA (ICD: M08 or M09.0) in two quarters at the age of 16 and continuous insurance until the age of 20 were included. Outpatient health care utilisation, prescribed antirheumatic drugs and diagnosis maintenance were analysed over four consecutive years for all YP with JIA and for the subgroup on disease-modifying antirheumatic drugs (DMARDs) at the age of 16. RESULTS: A total of 256 YP with JIA (67{\%} female) were followed during the transfer period, 115 of them received (DMARDs) at the age of 16. At the age of 20, 30{\%} of all 256 YP utilised adult specialty care, 59{\%} still had a JIA diagnosis and 30{\%} were treated with DMARDs. Of those 115 YP, treated with DMARDs at the age of 16 and in need of follow-up, 49{\%} had visited an adult rheumatologist at the age of 20, 75{\%} had a JIA diagnosis and 56{\%} were on DMARDs. Those 49{\%} YP with successful transfer to adult specialty care had a JIA diagnosis in 93{\%} and were treated with DMARDs in 80{\%}. YP, who were only seen by general practitioners, had a JIA diagnosis in 54{\%} and received DMARDs in 27{\%}. CONCLUSIONS: One in two YP with JIA and a clear need for ongoing follow-up do not utilise adult rheumatologic care. The maintenance of JIA diagnosis and DMARD therapy depend on the utilisation of specialised care services.},
      author = {{Luque Ramos},
      A. and Hoffmann, Falk and Albrecht, Katinka and Klotsche, J. and Zink, Angela and Minden, K.},
      year = {2017},
      title = {Transition to adult rheumatology care is necessary to maintain DMARD therapy in young people with juvenile idiopathic arthritis},
      keywords = {*Juvenile idiopathic arthritis;*Paediatric and adult rheumatology;*Transition to Adult Care;Adolescent;Antirheumatic Agents/*therapeutic use;Arthritis, Juvenile/*drug therapy;Cohort Studies;Female;Humans;Male;Rheumatology;Young Adult},
      pages = {269--275},
      volume = {47},
      number = {2},
      issn = {0049-0172},
      journal = {Semin Arthritis Rheum},
      doi = {10.1016/j.semarthrit.2017.05.003} }
  • [article] bibtex
    A. Luque Ramos, K. Albrecht, A. Zink, und F. Hoffmann, "Rheumatologic care of nursing home residents with rheumatoid arthritis: a comparison of the year before and after nursing home admission" Rheumatol Int, vol. 37, iss. 12, pp. 2059-2064, 2017.
    @article{LuqueRamos.2017d, abstract = {The purpose of this study was to investigate health care for patients with rheumatoid arthritis (RA) before and after admission to nursing homes. Data of a German health insurance fund from persons with diagnostic codes of RA, aged~$\geq$65~years, admitted to a nursing home between 2010 and 2014 and continuously insured 1~year before and after admission were used. The proportion of patients with $\geq$1 rheumatologist visit and $\geq$1 prescription of biologic or conventional synthetic disease-modifying antirheumatic drugs (bDMARDs or csDMARDs), glucocorticoids and non-steroidal anti-inflammatory drugs (NSAIDs) in the year before and after admission were calculated. Predictors of rheumatologic care after admission were analyzed by multivariable logistic regression. Of 75,697 nursing home residents, 2485 (3.3{\%}) had RA (90.5{\%} female, mean age 83.8). Treatment by rheumatologists and prescription of antirheumatic drugs decreased significantly in the year after admission (rheumatologic visits: 17.6 to 9.1{\%},
      bDMARDs: 2.1 to 1.5{\%},
      csDMARDs: 22.5 to 16.5{\%},
      glucocorticoids: 46.5 to 43.1{\%},
      NSAIDs: 47.4 to 38.5{\%}). 60.2{\%} of patients in rheumatologic care received csDMARDs compared with 14.5{\%} without rheumatologic care. Rheumatologic care before admission to a nursing home strongly predicted rheumatologic care thereafter (OR 33.8, 95{\%}-CI 23.2-49.2). Younger age and lower care level (reflecting need of help) were also associated with a higher chance of rheumatologic care. Rheumatologic care is already infrequent in old patients with RA and further decreases after admission to a nursing home. Patients without rheumatologic care are at high risk of insufficient treatment for their RA. Admission to a nursing home further increases this risk.},
      author = {{Luque Ramos},
      A. and Albrecht, Katinka and Zink, Angela and Hoffmann, Falk},
      year = {2017},
      title = {Rheumatologic care of nursing home residents with rheumatoid arthritis: a comparison of the year before and after nursing home admission},
      keywords = {Age Factors;Aged;Aged, 80 and over;Anti-Inflammatory Agents, Non-Steroidal/therapeutic use;Antirheumatic Agents/*therapeutic use;Arthritis, Rheumatoid/epidemiology/*therapy;Case-Control Studies;Claims data;Cohort Studies;Female;Germany;Health services research;Homes for the Aged/standards/*statistics {\&} numerical data;Humans;Insurance, Health;Male;Nursing home residents;Nursing Homes/standards/*statistics {\&} numerical data;Regression Analysis;Rheumatoid arthritis;Rheumatology/standards/*statistics {\&} numerical data;Sex Factors},
      pages = {2059--2064},
      volume = {37},
      number = {12},
      issn = {0172-8172},
      journal = {Rheumatol Int},
      doi = {10.1007/s00296-017-3791-5} }
  • [article] bibtex
    N. Reiss, T. Schmidt, F. Müller-von-Aschwege, W. Thronicke, J. D. Hoffmann, J. I. Röbesaat, E. Deniz, A. Hein, H. Krumm, F. Stewing, D. Willemsen, J. D. Schmitto, und C. Feldmann, "Telemonitoring and medical care of heart failure patients supported by left ventricular assist devices -The medolution project" Studies in Health Technology and Informatics, vol. 236, pp. 267-274, 2017.
    @article{Reiss.2017, abstract = {Long-term survival after left ventricular assist device (LVAD) implantation in heart failure patients is mainly determined by a sophisticated after-care. Ambulatory visits only take place every 12 weeks. In case of life-threatening complications (pump thrombosis, driveline infection) this might lead to delayed diagnosis and delayed intervention. It is the intention of the international project Medolution (Medical care evolution) to develop new approaches in order to create best structures for telemonitoring of LVAD patients. In the very early period of the project a questionnaire was sent to 180 LVAD patients to evaluate the need and acceptance of telemonitoring. Thereafter, a graphical user interface (GUI) mockup was developed as one of the first steps to improve the continuous contact between the LVAD patient and the physician. As a final goal the Medolution project aims to bundle all relevant informations from different data sources into one platform in order to provide the physician a comprehensive overview of a patient's situation. In the systems background a big data analysis should run permanently and should try to detect abnormalities and correlations as well. At crucial events, a notification system should inform the physician and should provide the causing data via a decision support system. With this new system we are expecting early detection and prevention of common and partially life-threatening complications, less readmissions to the hospital, an increase in quality of life for the patients and less costs for the health care system as well.},
      author = {Reiss, Nils and Schmidt, Thomas and M{\"u}ller-von-Aschwege, Frerk and Thronicke, Wolfgang and Hoffmann, Jan Dirk and R{\"o}besaat, Jenny Inge and Deniz, Ezin and Hein, Andreas and Krumm, Heiko and Stewing, Franz-Josef and Willemsen, Detlev and Schmitto, Jan Dieter and Feldmann, Christina},
      year = {2017},
      title = {Telemonitoring and medical care of heart failure patients supported by left ventricular assist devices -The medolution project},
      keywords = {Disease management;Heart failure;Left ventricular assist device;Remote monitoring;Telemonitoring},
      pages = {267--274},
      volume = {236},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      doi = {10.3233/978-1-61499-759-7-267},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28508806},
      file = {Reiss et al. - 2017 - Telemonitoring and medical care of heart failure patients supported by left ventricular assist devices -The medolu:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Reiss et al. - 2017 - Telemonitoring and medical care of heart failure patients supported by left ventricular assist devices -The medolu.pdf:pdf} }
  • [article] bibtex
    C. Schröder, M. Dörks, B. Kollhorst, T. Blenk, R. W. Dittmann, E. Garbe, und O. Riedel, "Outpatient antipsychotic drug use in children and adolescents in Germany between 2004 and 2011" Eur Child Adolesc Psychiatry, vol. 26, iss. 4, pp. 413-420, 2017.
    @article{Schroder.2017, abstract = {Studies from different countries showed increasing use of antipsychotics in pediatric patients. However, these studies were methodologically limited and could not assess underlying diagnoses and off-label use sufficiently. This is the first study to examine antipsychotic prescriptions in a representative sample of minors over a long period, looking at changes regarding substances and drug classes, underlying diagnoses, and the rate of off-label use. Claims data of about two million pediatric subjects were used to calculate annual prevalences and incidence rates of antipsychotic prescriptions for the years 2004-2011. Analyses were stratified by sex, age, and drug type. Numbers of prescriptions, frequencies of diseases/disorders, the prescribing physicians' specialties, and the share of off-label prescriptions were examined. During the study period, the prevalence of antipsychotic prescriptions ranged between 2.0 and 2.6 per 1000 minors. Antipsychotic prescriptions in children younger than 6~years decreased from 2.42 per 1000 subjects in 2004 to 0.48 in 2011. Among antipsychotic users, 47.0~{\%} had only one prescription and hyperkinetic disorder was, by far, the most frequent diagnosis. The annual share of off-label prescriptions varied between 61.0 and 69.5~{\%}. Antipsychotics were mainly prescribed to manage aggressive and impulsive behaviors in hyperkinetic disorder patients. This explains the high share of off-label prescriptions but raises concerns, since efficacy and safety of antipsychotics in this indication have not been sufficiently investigated. The decreasing antipsychotic use in younger children and the high proportion of antipsychotic users with one-time prescriptions are striking and should be further investigated in the future.},
      author = {Schr{\"o}der, C. and D{\"o}rks, Michael and Kollhorst, Bianca and Blenk, T. and Dittmann, R. W. and Garbe, E. and Riedel, O.},
      year = {2017},
      title = {Outpatient antipsychotic drug use in children and adolescents in Germany between 2004 and 2011},
      keywords = {Adolescent;Adolescents;Antipsychotic Agents/administration {\&} dosage/*therapeutic use;antipsychotics;Attention Deficit Disorder with Hyperactivity/drug therapy/epidemiology;Child;Child, Preschool;Children;Cross-Sectional Studies;Databases, Pharmaceutical;Drug Prescriptions/*statistics {\&} numerical data;Epidemiology;Female;Germany/epidemiology;Humans;incidence;Infant;Infant, Newborn;Male;Mental Disorders/*drug therapy/epidemiology;Neuroleptics;off-label use;Off-Label Use/*statistics {\&} numerical data;Outpatients/*statistics {\&} numerical data;Practice Patterns, Physicians'/statistics {\&} numerical data/*trends;Prevalence},
      pages = {413--420},
      volume = {26},
      number = {4},
      issn = {1018-8827},
      journal = {Eur Child Adolesc Psychiatry},
      doi = {10.1007/s00787-016-0905-7} }
  • [article] bibtex
    C. Schröder, M. Dörks, B. Kollhorst, T. Blenk, R. W. Dittmann, E. Garbe, und O. Riedel, "Outpatient antidepressant drug use in children and adolescents in Germany between 2004 and 2011" Pharmacoepidemiol Drug Saf, vol. 26, iss. 2, pp. 170-179, 2017.
    @article{Schroder.2017b, abstract = {PURPOSE: Recent studies on the utilization of antidepressant drugs in minors are scarce, methodologically limited, and do not factor in off-label use sufficiently. Beyond that, little is known about the short treatment durations that have been observed for many young antidepressant users. The present study examined antidepressant use in pediatric patients aged 0 to 17 years over time, investigated changes regarding the prescribed drugs, analyzed underlying diagnoses, and assessed the rate of off-label use. METHODS: We used claims data of roughly two million individuals to calculate annual prevalence and incidence rates of antidepressant prescriptions for the years 2004 to 2011. Analyses were stratified by age, sex, and drug type. For antidepressant users, numbers of prescriptions, frequencies of disorders/diseases, and specialties of the prescribing physicians were examined. The share of off-label prescriptions was calculated for each year. RESULTS: The prescription prevalence of antidepressants ranged between 1.7 and 2.1 per 1000 minors. The use of tricyclic antidepressants decreased from 0.9 to 0.6 prescriptions per 1000 minors, while the use of selective serotonin reuptake inhibitors increased from 0.5 to 1.1. Of the patients with an antidepressant prescription, 46.4{\%} only received one prescription. Depression was by far the most frequent diagnosis among all antidepressant users as well as among subjects with only one prescription. In 2011, 36.3{\%} of all prescriptions were off-label. CONCLUSIONS: The high proportion of single prescriptions, even in patients with a diagnosed depression, and the high rate of off-label use are particularly noteworthy and should be further investigated in future studies. Copyright {\copyright} 2016 John Wiley {\&} Sons, Ltd.},
      author = {Schr{\"o}der, C. and D{\"o}rks, Michael and Kollhorst, Bianca and Blenk, T. and Dittmann, R. W. and Garbe, E. and Riedel, O.},
      year = {2017},
      title = {Outpatient antidepressant drug use in children and adolescents in Germany between 2004 and 2011},
      keywords = {*Antidepressants;*children;*epidemiology;*Off-Label Use;*pharmacoepidemiology;*ssri;*tca;Adolescent;Antidepressive Agents, Tricyclic/administration {\&} dosage/therapeutic use;Antidepressive Agents/administration {\&} dosage/*therapeutic use;Child;Child, Preschool;Cross-Sectional Studies;Depression/*drug therapy/epidemiology;Female;Germany;Humans;incidence;Infant;Male;Off-Label Use/*statistics {\&} numerical data;Outpatients;Practice Patterns, Physicians'/*statistics {\&} numerical data;Prevalence;Serotonin Uptake Inhibitors/administration {\&} dosage/therapeutic use;Time Factors},
      pages = {170--179},
      volume = {26},
      number = {2},
      issn = {1053-8569},
      journal = {Pharmacoepidemiol Drug Saf},
      doi = {10.1002/pds.4138} }
  • [article] bibtex
    C. Schröder, M. Dörks, B. Kollhorst, T. Blenk, R. W. Dittmann, E. Garbe, und O. Riedel, "Extent and Risks of Antipsychotic Off-Label Use in Children and Adolescents in Germany Between 2004 and 2011" J Child Adolesc Psychopharmacol, vol. 27, iss. 9, pp. 806-813, 2017.
    @article{Schroder.2017c, abstract = {OBJECTIVE: Only little is known about antipsychotic (AP) off-label use (OLU) in pediatric populations. It was the aim of this study to examine the frequency as well as the risks of off-label AP use in underaged patients. METHODS: To calculate the frequency of off-label AP prescriptions for the years 2004-2011, we used claims data of more than two million minors aged 0-17 years. Off-label prescriptions were analyzed with regard to type of OLU, physician specialty, and underlying diagnoses. Incidence rates of selected adverse events were calculated for on-label as well as for OLU. The risk of poisoning associated with on- or OLU was assessed in a nested case-control study. RESULTS: The annual share of pediatric AP users with off-label prescriptions varied between 52.3{\%} and 71.1{\%}. OLU by indication (42.8{\%}-66.5{\%}) was the most common type of OLU. Of the subjects with OLU by indication, 52.5{\%} had a diagnosis of hyperkinetic disorder. Adverse events were scarce (incidence rates between 0.8 and 8.6 per 10,000 person-years), and no significant difference was observed between on- and OLU. CONCLUSION: Because of their frequent use in hyperkinetic disorder patients, APs are commonly prescribed off-label for minors. Since OLU by contraindication was rare and the risk of the adverse events under study was similarly small for on- and OLU, this is not necessarily an indication for inappropriate treatment. It rather indicates that further randomized studies are needed to examine efficacy and safety of pediatric AP use in this indication.},
      author = {Schr{\"o}der, C. and D{\"o}rks, Michael and Kollhorst, Bianca and Blenk, T. and Dittmann, R. W. and Garbe, E. and Riedel, O.},
      year = {2017},
      title = {Extent and Risks of Antipsychotic Off-Label Use in Children and Adolescents in Germany Between 2004 and 2011},
      keywords = {*Off-Label Use;Adolescents;Antipsychotic Agents/*therapeutic use;antipsychotics;Attention Deficit Disorder with Hyperactivity/*drug therapy;Child;Children;Female;Germany;Humans;Male;off-label use;Practice Patterns, Physicians'/statistics {\&} numerical data;Risk Factors;risks},
      pages = {806--813},
      volume = {27},
      number = {9},
      issn = {1044-5463},
      journal = {J Child Adolesc Psychopharmacol},
      doi = {10.1089/cap.2016.0202} }
  • [article] bibtex
    C. Schröder, M. Dörks, B. Kollhorst, T. Blenk, R. W. Dittmann, E. Garbe, und O. Riedel, "Extent and risks of antidepressant off-label use in children and adolescents in Germany between 2004 and 2011" Pharmacoepidemiol Drug Saf, vol. 26, iss. 11, pp. 1395-1402, 2017.
    @article{Schroder.2017d, abstract = {PURPOSE: So far, only little is known about antidepressant off-label use in pediatric patients. This is the first study examining the prevalence and the risks of off-label antidepressant prescriptions in minors over time in Germany and analyzing patterns regarding age, sex, drug class, and type of off-label use. METHODS: We used claims data of about two million individuals ({\textless}18~y) to calculate the share of off-label antidepressant prescriptions for the years 2004 to 2011, stratified by age, sex, and drug class. Off-label prescriptions were analyzed regarding underlying diagnoses, the prescribing doctor's specialty, and the type of off-label use. Incidence rates of adverse events were calculated for off- and on-label use, and the risk of suicidal events associated with off- or on-label use was examined in a nested case-control study. RESULTS: The prevalence of off-label prescriptions decreased from 58.0{\%} to 40.9{\%}. Selective serotonin reuptake inhibitors were more frequently prescribed off-label than tricyclic antidepressants (37.7{\%} vs 17.5{\%} in 2011). The most common type of off-label use was off-label use by age, followed by off-label use by indication, and off-label use by contraindication. Adverse events were rare with no significant differences between on- and off-label use. CONCLUSIONS: Although off-label antidepressant use in minors decreased over time, it is still common. However, this rather indicates a lack of approved drugs for the treatment of depression in this population than inappropriate medical treatment. This is supported by the fact that off-label use was not associated with a higher risk of adverse events than on-label use.},
      author = {Schr{\"o}der, C. and D{\"o}rks, Michael and Kollhorst, Bianca and Blenk, T. and Dittmann, R. W. and Garbe, E. and Riedel, O.},
      year = {2017},
      title = {Extent and risks of antidepressant off-label use in children and adolescents in Germany between 2004 and 2011},
      keywords = {Adolescent;Adolescents;Age Factors;antidepressants;Antidepressive Agents, Tricyclic/adverse effects/therapeutic use;Antidepressive Agents/adverse effects/*therapeutic use;Case-Control Studies;Child;Child, Preschool;Children;Cohort Studies;Epidemiology;Female;Germany/epidemiology;Humans;incidence;Infant;Male;off-label use;Off-Label Use/*statistics {\&} numerical data;Practice Patterns, Physicians';Prevalence;Serotonin Uptake Inhibitors/adverse effects/therapeutic use;Sex Factors;Suicidal Ideation;suicidality},
      pages = {1395--1402},
      volume = {26},
      number = {11},
      issn = {1053-8569},
      journal = {Pharmacoepidemiol Drug Saf},
      doi = {10.1002/pds.4289} }
  • [incollection] bibtex
    S. Fudickar, S. Hellmers, J. Prellberg, K. Barjenbruch, T. de Graaff, S. Warsitz, und A. Hein, "IMUAnnotate: On Annotating Inertial-based Activity Data for Machine Learning" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017.
    @incollection{Fudickar.2017b, abstract = {This article introduces a software-tool that supports quick and intuitive annotation of activity labels on inertial-based sensor-data recordings. Thereby, the preparation of corresponding (training and evaluation) data-sets for machine learning algorithms can be optimized. We further propose the use of a normed and extendable classification scheme for such annotation, to increase the reusability and exchange of annotated data-sets among groups. Finally we discuss essential requirements and our current state of preparation towards such a normed approach.},
      author = {Fudickar, Sebastian and Hellmers, Sandra and Prellberg, Jonas and Barjenbruch, Kjel and de Graaff, Thiess and Warsitz, Sebastian and Hein, Andreas},
      title = {IMUAnnotate: On Annotating Inertial-based Activity Data for Machine Learning},
      keywords = {informationen{\_}fehlen;Unpublished},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {Fudickar et al. - 2017 - IMUAnnotate On Annotating Inertial-based Activity Data for Machine Learning:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Fudickar et al. - 2017 - IMUAnnotate On Annotating Inertial-based Activity Data for Machine Learning.docx:docx} }
  • [article] bibtex
    J. Callhoff, A. Luque Ramos, A. Zink, F. Hoffmann, und K. Albrecht, "The Association of Low Income with Functional Status and Disease Burden in German Patients with Rheumatoid Arthritis: Results of a Cross-sectional Questionnaire Survey Based on Claims Data" J Rheumatol, vol. 44, iss. 6, pp. 766-772, 2017.
    @article{Callhoff.2017, abstract = {OBJECTIVE: To assess the influence of income on self-reported disease and work productivity outcomes. METHODS: Persons with rheumatoid arthritis (RA) diagnosis (International Classification of Diseases, 10th ed. codes M05/M06) on health insurance claims data in at least 2 quarters of 2013 were randomly selected. They were mailed questionnaires covering RA diagnosis, household income, functional capacity [Hannover functional status questionnaire (FFbH), 0-100], RA Impact of Disease questionnaire (RAID; 0-10), self-reported swollen joint count (SJC; 0-48), tender joint count (TJC; 0-50), and effect of RA on work productivity (change of work, fewer working hours, sick leave, application for disability pension, and others). Weighted multivariable linear regression models were used to assess the association between income and disease outcomes. RESULTS: A total of 1492 persons of working age who confirmed RA diagnosis were available for analysis. The mean age was 55 years, 82{\%} were women, and 74{\%} were under rheumatologic care. A total of 27{\%},
      52{\%},
      and 21{\%} had a low ({\textless} euro1500), medium (euro1500-3200), and high monthly income ({\textgreater} euro3200), respectively. Respondents with low income had the worst mean FFbH, RAID, SJC, and TJC values. This was confirmed in the regression model: mean FFbH low versus high income -8.65 (95{\%} CI -9.72 to -7.58), RAID 0.73 (0.59-0.86), and SJC 3.47 (2.86-4.08). Sick leave (8.7{\%}/3.5{\%}/1.8{\%}) and disability pension (18.1{\%}/9.6{\%}/6.9{\%}) were more frequent in patients with low versus medium versus high income (p {\textless} 0.05). CONCLUSION: The association of low income with a higher disease burden, more functional disability, and higher rates of work loss emphasizes the need to focus on these outcomes when choosing treatment strategies for patients in the lower income groups.},
      author = {Callhoff, Johanna and {Luque Ramos},
      A. and Zink, Angela and Hoffmann, Falk and Albrecht, Katinka},
      year = {2017},
      title = {The Association of Low Income with Functional Status and Disease Burden in German Patients with Rheumatoid Arthritis: Results of a Cross-sectional Questionnaire Survey Based on Claims Data},
      keywords = {*Disability Evaluation;*disease burden;*epidemiology;*healthcare;*rheumatoid arthritis;Adult;Arthritis, Rheumatoid/*diagnosis;Cross-Sectional Studies;Female;Humans;Income;Male;Middle Aged;Poverty;Severity of Illness Index;Sick Leave;Surveys and Questionnaires},
      pages = {766--772},
      volume = {44},
      number = {6},
      issn = {0315-162X (Print) 0315-162x},
      journal = {J Rheumatol},
      doi = {10.3899/jrheum.160966},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28412709} }
  • [article] bibtex
    J. Czwikla, K. Jobski, und T. Schink, "The impact of the lookback period and definition of confirmatory events on the identification of incident cancer cases in administrative data" BMC Med Res Methodol, vol. 17, iss. 1, p. 122, 2017.
    @article{Czwikla.2017, abstract = {BACKGROUND: This cohort study examined the impact of the lengths of lookback and confirmation periods as well as the definition of confirmatory events on the number of incident cancer cases identified and age-standardized cumulative incidences (ACI) estimated in administrative data using German cancer registry data as a benchmark. METHODS: ACI per 100,000 insured persons for breast, prostate and colorectal cancer were estimated using BARMER Statutory Health Insurance claims data. Incident cancer cases were defined as having an in- or outpatient diagnosis in 2013, no diagnosis in a lookback period of 1 year and a second diagnosis (or death) in a confirmation period of 1 quarter. We varied lookback periods from 1 to 7 years, confirmation periods from 1 to 4 quarters as well as the definition of confirmatory events and compared ACI estimates to cancer registry data. RESULTS: ACI were higher for breast (138.7) and prostate (103.6) but lower for colorectal cancer (42.1) when compared to cancer registries (119.3, 98.0 and 45.5, respectively). Extending the lookback period to 7 years reduced ACI to 129.0, 95.1 and 38.3. An extended confirmation period of 4 quarters increased ACI to 151.3, 114.9 and 46.8. Including breast and colorectal surgeries as a confirmatory event reduced ACI to 114.9 and 37.1, respectively. CONCLUSIONS: The choice of lookback and confirmation periods and the definition of confirmatory events have considerable impact on the number of incident cancer cases identified and ACI estimated. Researchers need to be aware of potential misclassification when identifying incident cancer cases in administrative data. Further validation studies as well as studies using administrative data to estimate cancer incidences should consider several choices of the lookback and confirmation periods and the definition of confirmatory events to show how these parameters impact the validity and robustness of their results.},
      author = {Czwikla, Jonas and Jobski, Kathrin and Schink, Tania},
      year = {2017},
      title = {The impact of the lookback period and definition of confirmatory events on the identification of incident cancer cases in administrative data},
      keywords = {*Registries;Administrative claims;Algorithms;Breast neoplasms;Breast Neoplasms/diagnosis/*epidemiology;Cohort Studies;Colorectal neoplasms;Colorectal Neoplasms/diagnosis/*epidemiology;Epidemiology;Female;Health services research;Humans;incidence;International classification of diseases;Male;Middle Aged;Neoplasms;Prostatic neoplasms;Prostatic Neoplasms/diagnosis/*epidemiology;Validation},
      pages = {122},
      volume = {17},
      number = {1},
      issn = {1471-2288 (Electronic) 1471-2288 (Linking)},
      journal = {BMC Med Res Methodol},
      doi = {10.1186/s12874-017-0407-4},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28806932},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556662} }
  • [article] bibtex
    M. Dörks, K. Allers, G. Schmiemann, S. Herget-Rosenthal, und F. Hoffmann, "Inappropriate Medication in Non-Hospitalized Patients With Renal Insufficiency: A Systematic Review" J Am Geriatr Soc, vol. 65, iss. 4, pp. 853-862, 2017.
    @article{Dorks.2017d, abstract = {OBJECTIVES: Renal insufficiency is common among older patients and, accordingly, renally excreted drugs may require an adjustment in dosage for them. Rates of non-adherence to renal dosing guidelines range from 19{\%} to 70{\%} across all settings, with the highest rate occurring in outpatient care. However, there is a paucity of research in this field. The main objective of this systematic review is to assess how often drugs are inappropriately prescribed in non-hospitalized patients with renal insufficiency. DESIGN: A systematic literature search was performed. Data were identified from three electronic databases: PubMed, CINAHL, and Scopus. Studies were included if they reported quantitative data on inappropriate drug use with respect to renal function in non-hospitalized patients. RESULTS: Our search strategy resulted in 2,403 hits, of which 18 articles satisfied the criteria for inclusion. Mean estimated glomerular filtration rate ranged from 36.0 to 60.4 mL/min. Prevalence of renally inappropriate drug use ranged from 1{\%} to 37{\%} in outpatient settings other than nursing homes, and from 6{\%} to 43{\%} in nursing homes. Eight of the studies we included identified predictors for use of drugs inappropriate for kidney function. Most frequently determined risk factors were increasing age and a high number of prescribed drugs. CONCLUSION: Lack of dose adjustment for renal impairment seems to be a common problem, even in outpatients. However, the differences in methodologies used in these studies hampered any direct comparison. Accepted and comparable standards regarding the drugs included in the studies as well as estimation of renal function would be beneficial.},
      author = {D{\"o}rks, Michael and Allers, Katharina and Schmiemann, Guido and Herget-Rosenthal, Stefan and Hoffmann, Falk},
      year = {2017},
      title = {Inappropriate Medication in Non-Hospitalized Patients With Renal Insufficiency: A Systematic Review},
      keywords = {*dose adjustment;*inappropriate medication;*Inappropriate Prescribing;*nursing home;*Outpatients;*renal insufficiency;Aged;Glomerular Filtration Rate;Humans;Prescription Drugs/*pharmacokinetics;Renal Insufficiency/*metabolism;Risk Factors},
      pages = {853--862},
      volume = {65},
      number = {4},
      issn = {1532-5415 (Electronic) 0002-8614 (Linking)},
      journal = {J Am Geriatr Soc},
      doi = {10.1111/jgs.14809},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28240771} }
  • [article] bibtex
    F. Hoffmann und D. Koller, "[Different Regions, Differently Insured Populations? Socio-demographic and Health-related Differences Between Insurance Funds]" Das Gesundheitswesen, vol. 79, iss. 1, p. e1-e9, 2017.
    @article{Hoffmann.2017b, abstract = {Objectives: Analyses of health insurance claims data are getting more important in public health and health services research. Since there are several different health insurance funds in Germany, the specific characteristics of regional and socio-demographic population covered by a single fund has to be considered. The aim of this study is to evaluate the differences in socio-demographic and health-related variables between health insurance funds. Methods: This study is based on the GEDA-Study 2009 and 2010, 2 representative cross-sectional telephone surveys (n=42 534). We included socio-economic factors as well as information on area of residence and health-related variables to health status, health behavior and cardiovascular diseases. Results: There are fewer privately insured persons in the eastern regions of Germany. Insurants of the public health insurances have a lower socio-economic status and many have a migration background. Similar results can be found for smoking, obesity and cardiovascular factors. These differences between funds were found in many regional analyses. Conclusions: Especially differences in socio-economic factors are constant between insurance funds and regions. Therefore, the results show that analyses of one single health insurance fund cannot be generalized to the whole population. To ensure precise estimates on health services, morbidity or quality monitoring, we need data sets that integrate more funds.},
      author = {Hoffmann, Falk and Koller, D.},
      year = {2017},
      title = {[Different Regions, Differently Insured Populations? Socio-demographic and Health-related Differences Between Insurance Funds]},
      keywords = {*Health Status;Adult;Aged;Cross-Sectional Studies;Germany/epidemiology;Health Care Rationing/*statistics {\&} numerical data;Health Care Surveys;Health Services Accessibility/*statistics {\&} numerical data;Humans;Insurance Coverage/*statistics {\&} numerical data;Male;National Health Programs/*statistics {\&} numerical data;Socioeconomic Factors;Transients and Migrants/*statistics {\&} numerical data;Young Adult},
      pages = {e1-e9},
      volume = {79},
      number = {1},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Verschiedene Regionen, verschiedene Versichertenpopulationen? Soziodemografische und gesundheitsbezogene Unterschiede zwischen Krankenkassen.},
      doi = {10.1055/s-0035-1564074} }
  • [article] bibtex
    K. Jobski, B. Kollhorst, E. Garbe, und T. Schink, "The Risk of Ischemic Cardio- and Cerebrovascular Events Associated with Oxycodone-Naloxone and Other Extended-Release High-Potency Opioids: A Nested Case-Control Study" Drug Saf, vol. 40, iss. 6, pp. 505-515, 2017.
    @article{Jobski.2017, abstract = {INTRODUCTION: In Germany, an extended-release (ER) combination of the high-potency opioid (HPO) oxycodone and the antagonist naloxone was approved in 2006. In recent years, the cardio- and cerebrovascular safety of opioid antagonists and of opioids themselves has been discussed. OBJECTIVES: The objective of this study was to estimate the risk of major ischemic cardio- and cerebrovascular events in patients receiving ER oxycodone-naloxone compared with those receiving other ER HPOs. METHODS: We used the German Pharmacoepidemiological Research Database (GePaRD) to conduct a nested case-control study (2006-2011) within a cohort of ER HPO users. Cases were defined as patients hospitalized for acute myocardial infarction (MI) or ischemic stroke (IS). For each case, up to ten controls were selected by risk-set sampling. Using conditional logistic regression, confounder-adjusted odds ratios (aORs) and 95{\%} confidence intervals (CIs) were obtained for the risk of MI/IS associated with (1) current HPO treatment, (2) recent discontinuation, or (3) recent switch of HPO therapy compared with past treatment. RESULTS: In 309,936 ER HPO users, 12,384 MI/IS events were detected, resulting in a crude incidence rate of 19.48 (95{\%} CI 19.14-19.82) per 1000 person years. A small but significantly elevated aOR was found for morphine (1.12; 95{\%} CI 1.04-1.22) but not for oxycodone-naloxone. Recent discontinuation and recent switch of any ER HPO also had a significant impact on the outcome (aOR 1.12; 95{\%} CI 1.04-1.21 and 1.25; 95{\%} CI 1.03-1.52, respectively). CONCLUSIONS: Our study does not indicate an association between oxycodone-naloxone and ischemic cardio- or cerebrovascular events. However, our findings do suggest that every change in ER HPO therapy should be conducted with caution.},
      author = {Jobski, Kathrin and Kollhorst, Bianca and Garbe, E. and Schink, Tania},
      year = {2017},
      title = {The Risk of Ischemic Cardio- and Cerebrovascular Events Associated with Oxycodone-Naloxone and Other Extended-Release High-Potency Opioids: A Nested Case-Control Study},
      keywords = {Aged;Aged, 80 and over;Analgesics, Opioid/*adverse effects;Case-Control Studies;Cerebrovascular Disorders/*chemically induced;Delayed-Action Preparations/*adverse effects;Female;Germany;Humans;Male;Middle Aged;Myocardial Ischemia/*chemically induced;Naloxone/*adverse effects;Oxycodone/*adverse effects;Retrospective Studies;Risk},
      pages = {505--515},
      volume = {40},
      number = {6},
      issn = {1179-1942 (Electronic) 0114-5916 (Linking)},
      journal = {Drug Saf},
      doi = {10.1007/s40264-017-0511-8},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28194654} }
  • [article] bibtex
    K. Jobski, A. Luque Ramos, K. Albrecht, und F. Hoffmann, "Pain, depressive symptoms and medication in German patients with rheumatoid arthritis-results from the linking patient-reported outcomes with claims data for health services research in rheumatology (PROCLAIR) study" Pharmacoepidemiol Drug Saf, vol. 26, iss. 7, pp. 766-774, 2017.
    @article{Jobski.2017c, abstract = {PURPOSE: Pain and depressive symptoms are common in patients with rheumatoid arthritis (RA). Information on the prevalence and treatment of both conditions in German RA patients is scarce. METHODS: Using data from a nationwide statutory health insurance fund (BARMER GEK), 6193 RA patients aged 18 to 79 years were provided with a questionnaire covering a variety of items such as demographics, medical condition and quality of life in 2015. Pain caused by the joint disorder (11-point scale) was classified as none existent/mild, moderate or severe. Depressive symptoms were determined using the World Health Organization's five-item Well-being Index and categorized as none existent, mild or moderate/severe. Another item covered additional use of over-the-counter drugs. Data were linked to dispensation records. RESULTS: A total of 3140 RA patients were included. Median age was 66 years (79{\%} female). About 70{\%} of patients were classified as having moderate or severe pain. Depressive symptoms were found in 52{\%} and were far more common among patients with higher pain levels. Analgesic treatment ranged from 45{\%} to 76{\%} (non-opioid analgesics) and from 6{\%} to 33{\%} (opioids) in patients with no/mild pain and those reporting severe pain, respectively. In patients reporting moderate or severe pain, substantially higher prevalences of opioid use were observed among those with depressive symptoms. Depending on depressive symptoms, antidepressant use ranged from 7{\%} to 37{\%}. Overall, over-the-counter drug use varied between 30{\%} and 59{\%}. CONCLUSIONS: Pain and depressive symptoms are highly prevalent in German RA patients, often present together and influence each other's treatment. Copyright (c) 2017 John Wiley {\&} Sons, Ltd.},
      author = {Jobski, Kathrin and {Luque Ramos},
      A. and Albrecht, Katinka and Hoffmann, Falk},
      year = {2017},
      title = {Pain, depressive symptoms and medication in German patients with rheumatoid arthritis-results from the linking patient-reported outcomes with claims data for health services research in rheumatology (PROCLAIR) study},
      keywords = {*Patient Reported Outcome Measures;Adolescent;Adult;Aged;analgesics;Analgesics/*therapeutic use;antidepressants;Antidepressive Agents/*therapeutic use;Arthritis, Rheumatoid/*complications/epidemiology;Depression/drug therapy/*etiology;depressive symptoms;Female;Germany/epidemiology;Health services research;Humans;Male;Middle Aged;over-the-counter drugs;pain;Pain/*etiology;pharmacoepidemiology;Quality of Life;Rheumatoid arthritis;Rheumatology;Young Adult},
      pages = {766--774},
      volume = {26},
      number = {7},
      issn = {1053-8569},
      journal = {Pharmacoepidemiol Drug Saf},
      doi = {10.1002/pds.4202},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28345245} }
  • [article] bibtex
    I. Kamp-Becker, L. Poustka, C. Bachmann, S. Ehrlich, F. Hoffmann, P. Kanske, P. Kirsch, S. Krach, F. M. Paulus, M. Rietschel, S. Roepke, V. Roessner, T. Schad-Hansjosten, T. Singer, S. Stroth, S. Witt, und A. K. Wermter, "Study protocol of the ASD-Net, the German research consortium for the study of Autism Spectrum Disorder across the lifespan: from a better etiological understanding, through valid diagnosis, to more effective health care" BMC Psychiatry, vol. 17, iss. 1, p. 206, 2017.
    @article{KampBecker.2017, abstract = {BACKGROUND: Autism Spectrum Disorder (ASD) is a severe, lifelong neurodevelopmental disorder with early onset that places a heavy burden on affected individuals and their families. Due to the need for highly specialized health, educational and vocational services, ASD is a cost-intensive disorder, and strain on health care systems increases with increasing age of the affected individual. METHODS: The ASD-Net will study Germany's largest cohort of patients with ASD over the lifespan. By combining methodological expertise from all levels of clinical research, the ASD-Net will follow a translational approach necessary to identify neurobiological pathways of different phenotypes and their appropriate identification and treatment. The work of the ASD-Net will be organized into three clusters concentrating on diagnostics, therapy and health economics. In the diagnostic cluster, data from a large, well-characterized sample (N~=~2568) will be analyzed to improve the efficiency of diagnostic procedures. Pattern classification methods (machine learning) will be used to identify algorithms for screening purposes. In a second step, the developed algorithm will be tested in an independent sample. In the therapy cluster, we will unravel how an ASD-specific social skills training with concomitant oxytocin administration can modulate behavior through neurobiological pathways. For the first time, we will characterize long-term effects of a social skills training combined with oxytocin treatment on behavioral and neurobiological phenotypes. Also acute effects of oxytocin will be investigated to delineate general and specific effects of additional oxytocin treatment in order to develop biologically plausible models for symptoms and successful therapeutic interventions in ASD. Finally, in the health economics cluster, we will assess service utilization and ASD-related costs in order to identify potential needs and cost savings specifically tailored to Germany. The ASD-Net has been established as part of the German Research Network for Mental Disorders, funded by the BMBF (German Federal Ministry of Education and Research). DISCUSSION: The highly integrated structure of the ASD-Net guarantees sustained collaboration of clinicians and researchers to alleviate individual distress, harm, and social disability of patients with ASD and reduce costs to the German health care system. TRIAL REGISTRATION: Both clinical trials of the ASD-Net are registered in the German Clinical Trials Register: DRKS00008952 (registered on August 4, 2015) and DRKS00010053 (registered on April 8, 2016).},
      author = {Kamp-Becker, I. and Poustka, L. and Bachmann, C. and Ehrlich, S. and Hoffmann, Falk and Kanske, P. and Kirsch, P. and Krach, S. and Paulus, F. M. and Rietschel, M. and Roepke, S. and Roessner, V. and Schad-Hansjosten, T. and Singer, T. and Stroth, S. and Witt, S. and Wermter, A. K.},
      year = {2017},
      title = {Study protocol of the ASD-Net, the German research consortium for the study of Autism Spectrum Disorder across the lifespan: from a better etiological understanding, through valid diagnosis, to more effective health care},
      keywords = {*ASD-net;*Autism spectrum disorder;*Biomedical Research;*diagnosis;*Disabled Persons;*Genetic;*German research network for mental disorders;*Health economics;*Oxytocin;*Screening;*Social competence training;*Therapy;Autism Spectrum Disorder/*diagnosis/*therapy;Cooperative Behavior;Female;Germany;Humans;Male;Research},
      pages = {206},
      volume = {17},
      number = {1},
      issn = {1471-244x},
      journal = {BMC Psychiatry},
      doi = {10.1186/s12888-017-1362-7},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455122} }
  • [article] bibtex
    A. Luque Ramos und F. Hoffmann, "[Differences in chronic back pain and joint disorders among health insurance funds : Results of a cross-sectional study based on the data of the Socioeconomic Panel from 2013]" Z Rheumatol, vol. 76, iss. 3, pp. 238-244, 2017.
    @article{LuqueRamos.2017c, abstract = {BACKGROUND: Health services research uses increasingly data from health insurance funds. It is well known that the funds differ with regard to sociodemographic characteristics and morbidity. It is uncertain if there are also differences in the prevalence of musculoskeletal disorders. OBJECTIVE: To compare the sociodemographic characteristics in various health insurance funds and the prevalence of joint disorders and chronic back pain. METHOD: The 30(th) wave (2013) of the German Socioeconomic Panel served as a database. Average age, sex distribution, nationality, education, and employment status were evaluated according to~the health insurance funds. The prevalence of joint disorders and chronic back pain were also stratified according to the insurance funds and standardized according to age and sex. RESULTS: A total of 19,146 participants were included. Most participants (4,934) were insured by AOK, followed by BKK (2,632) and BARMER GEK (2,398). There were huge differences among the health insurance funds with regard to the sociodemographic characteristics. For example, the proportion of unemployed insurants was between 33.3 {\%} (IKK) and 50.6 {\%} (AOK). The prevalence of joint disorders standardized according to age and sex (20.7 {\%}; 95 {\%} CI: 20.1-21.3) was between 17.4 {\%} (95 {\%} CI: 15.8-19.0; PKV) and 22.4 {\%} (95 {\%} CI: 21.1-23.6; AOK). The prevalence of chronic back pain (18.0 {\%}; 95 {\%} CI: 17.4-18.5) was between 13.5 {\%} (95 {\%} CI: 12.2-14.9; PKV) and 20.6 {\%} (95 {\%} CI: 19.4-21.8; AOK). CONCLUSION: There are differences in the prevalence of musculoskeletal disorders among health insurance funds. The extrapolation of analyses of one health insurance fund to the German population is thus limited.},
      author = {{Luque Ramos},
      A. and Hoffmann, Falk},
      year = {2017},
      title = {[Differences in chronic back pain and joint disorders among health insurance funds : Results of a cross-sectional study based on the data of the Socioeconomic Panel from 2013]},
      keywords = {*Health Care Surveys;Age Distribution;Back Pain/*economics/*epidemiology;Chronic Pain/economics/epidemiology;Cross-Sectional Studies;Educational Status;Employment;Female;Germany/epidemiology;Health services research;Humans;Insurance Claim Review;Insurance, Health, Reimbursement/*economics/statistics {\&} numerical data;Joint Diseases/*economics/*epidemiology;Male;Middle Aged;Morbidity;National Health Programs/economics/statistics {\&} numerical data;Prevalence;Rheumatoid arthritis;Sex Distribution;Socioeconomic Factors;Statutory health insurance},
      pages = {238--244},
      volume = {76},
      number = {3},
      issn = {0340-1855},
      journal = {Z Rheumatol},
      originalyear = {Kassenunterschiede bei chronischen R{\"u}ckenschmerzen und Gelenkerkrankungen : Ergebnisse einer Querschnittsstudie auf Grundlage der Daten des sozio{\"o}konomischen Panels von 2013.},
      doi = {10.1007/s00393-016-0178-z} }
  • [article] bibtex
    G. Schmiemann, A. Dehlfing, A. Pulst, und F. Hoffmann, "[Medication safety in nursing home residents with renal insufficiency - Results of a qualitative study]" Z Evid Fortbild Qual Gesundhwes, vol. 121, pp. 14-20, 2017.
    @article{Schmiemann.2017, abstract = {BACKGROUND: Nursing home residents often suffer from multimorbidity and polypharmacy. Impaired renal function and the lack of dose adjustments further increase the risk of adverse drug reactions (ADR). The aims of this qualitative study were to analyze the reasons for inadequate drug treatment and to identify possible intervention options to improve safety of drug treatment in nursing home residents with renal insufficiency. METHODS: Using a mixed-method approach a cross-sectional study and focus group discussions were performed in the project. Focus groups with general practitioners, nursing staff, nephrologists and pharmacists were held. Audiotapes were transcribed verbatim, qualitative content analysis of the transcripts according to Mayring was conducted using MAXQDA. RESULTS AND CONCLUSIONS: Focus groups discussed different aspects and possible interventions related to inadequate drug treatment in nursing home residents with renal insufficiency. The main topics identified were {\textquotedbl}health service situation{\textquotedbl},
      {\textquotedbl}reasons for ADR{\textquotedbl} and {\textquotedbl}interventions{\textquotedbl}. Regarding the current health service situation {\textquotedbl}infrastructure{\textquotedbl},
      {\textquotedbl}role of polypharmacy{\textquotedbl},
      {\textquotedbl}assessment of renal function{\textquotedbl} and the {\textquotedbl}different role models{\textquotedbl} were identified as relevant aspects for improving the safety of drug treatment in nursing homes. According to the participants, there is a lack of evidence-based standards regarding laboratory monitoring and estimation of kidney function.},
      author = {Schmiemann, Guido and Dehlfing, A. and Pulst, Alexandra and Hoffmann, Falk},
      year = {2017},
      title = {[Medication safety in nursing home residents with renal insufficiency - Results of a qualitative study]},
      keywords = {*Polypharmacy;Comorbidity;Cross-Sectional Studies;Drug Utilization/*statistics {\&} numerical data;Germany;Homes for the Aged;Humans;medication safety;Medikamentensicherheit;Niereninsuffizienz;nursing home;Nursing homes;Pflegeheim;polypharmacy;Polypharmazie;renal insufficiency;Renal Insufficiency/drug therapy/*metabolism},
      pages = {14--20},
      volume = {121},
      issn = {1865-9217},
      journal = {Z Evid Fortbild Qual Gesundhwes},
      originalyear = {Arzneimitteltherapiesicherheit bei Pflegeheimbewohnern mit eingeschrankter Nierenfunktion - Ergebnisse einer qualitativen Studie.},
      doi = {10.1016/j.zefq.2017.02.003},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28347697} }
  • [incollection] bibtex
    D. Brammen, H. Dewenter, V. Thiemann, R. W. Majeed, T. Xu, K. U. Heitmann, F. Walcher, S. Thun, und R. Röhrig, "Disseminating a Standard for Medical Records in Emergency Departments Among Different Software Vendors Using HL7 CDA" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 243, pp. 132-136.
    @incollection{Brammen.2017, abstract = {A standardized medical record for the emergency department (GEDMR) was released in Germany, but only sparsely and randomly implemented by emergency department (ED) electronic health record (EHR) vendors. A reason for this may be a lacking common language between the medical and the Health Information Technology (HIT) domain. HL7 clinical document architecture (CDA) may leverage this communication gap. This paper reports on the effects of a professional medical association record standard on EHR vendors and the German ED-EHR market. Standard records and data standards are developed and published by different institutions either on governmental, healthcare agency or medical association level. There are some standard records, especially by US cardiology associations, transformed into HL7 C-CDA. GEDMR was modeled as HL7 CDA with the use of interoperable terminologies like LOINC and SNOMED CT. Being part of an emergency department data registry development project, local deployment at 15 project hospitals receiving sufficient funding was performed. Two major ED-EHR vendors adapted GEDMR within their product including CDA export. 106,868 CDAs were produced in six hospitals until now. Four local implementations with four different ED-EHRs were developed, producing 42,256 CDAs. Five additional vendors are adapting or developing an ED-EHR. The GEDMR-CDA implementation guide with funding for implementation in project hospitals had a significant impact on the German ED-EHR market. Within two years after release, a broadening and increasingly self-enforcing support by German ED-EHR vendors is notable.},
      author = {Brammen, Dominik and Dewenter, Heike and Thiemann, Volker and Majeed, Raphael W. and Xu, Tingyan and Heitmann, Kai U. and Walcher, Felix and Thun, Sylvia and R{\"o}hrig, Rainer},
      title = {Disseminating a Standard for Medical Records in Emergency Departments Among Different Software Vendors Using HL7 CDA},
      pages = {132--136},
      volume = {243},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28883186} }
  • [incollection] bibtex
    D. Brammen, H. Dewenter, K. U. Heitmann, V. Thiemann, R. W. Majeed, F. Walcher, R. Röhrig, und S. Thun, "Mapping Equivalence of German Emergency Department Medical Record Concepts with SNOMED CT After Implementation with HL7 CDA" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 243, pp. 175-179.
    @incollection{Brammen.2017b, abstract = {INTRODUCTION The German Emergency Department Medical Record (GEDMR) was created by medical domain experts and healthcare providers providing a dataset as well as a form. The trauma module of GEDMR was syntactically standardized using HL7 CDA and semantically standardized using different terminologies including SNOMED CT, LOINC and proprietary coding systems. This study depicts the mapping accuracy with aforementioned syntactical and semantical standards in general and especially the content coverage of SNOMED CT. METHODS The specification of GEDMR (V2015.1) concepts with eHealth-standards HL7-CDA, LOINC, SNOMED CT was analyzed. A content coverage assessment was made using the ISO TR 12300 rating scheme, following descriptive analysis. RESULTS The trauma module of GEDMR contains 489 concepts, with 202 concepts expressed via HL7 CDA structure. It is possible to code 89 {\%} of the remaining concepts via SNOMED CT. 79 {\%} provide an advanced level of semantic interoperability, as they represent the source information either lexically or as an approved synonym. DISCUSSION The terminology binding problem is relevant when combining different standards for syntactic and semantic interoperability with best practice documents and reference specifications providing guidance. A national license and extension for SNOMED CT in Germany as well as an ongoing effort in contributing to the International Version of SNOMED CT would be necessary to gain full coverage for concepts in German Emergency Medicine and to leverage the associated standardization process.},
      author = {Brammen, Dominik and Dewenter, Heike and Heitmann, Kai U. and Thiemann, Volker and Majeed, Raphael W. and Walcher, Felix and R{\"o}hrig, Rainer and Thun, Sylvia},
      title = {Mapping Equivalence of German Emergency Department Medical Record Concepts with SNOMED CT After Implementation with HL7 CDA},
      pages = {175--179},
      volume = {243},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28883195} }
  • [incollection] bibtex
    R. W. Majeed, T. Xu, M. R. Stöhr, und R. Röhrig, "Li2b2-Façade: Simulation of i2b2 Data Warehouse Server and Client for Interaction with Other Systems" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 245, p. 1275.
    @incollection{Majeed.2017, abstract = {Since its release in 2004, the i2b2 data warehouse software has become a valuable tool for clinical researchers. Physicians can use its browser-based query frontend intuitively without additional training or reading through documentation. While the i2b2 software describes it's API as {\textquotedbl}REST{\textquotedbl},
      it is neither stateless nor does it follow the common guidelines for RESTful APIs. Thus, interfacing other software with i2b2's custom RPC-style XML-API is a very cumbersome process. To overcome these issues, we developed a lightweight software abstraction layer {\textquotedbl}lightweight i2b2 fa{\c{c}}ade{\textquotedbl} (li2b2-fa{\c{c}}ade).},
      author = {Majeed, Raphael W. and Xu, Tingyan and St{\"o}hr, Mark R. and R{\"o}hrig, Rainer},
      title = {Li2b2-Fa{\c{c}}ade: Simulation of i2b2 Data Warehouse Server and Client for Interaction with Other Systems},
      pages = {1275},
      volume = {245},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29295360} }
  • [incollection] bibtex
    R. W. Majeed, M. R. Stöhr, V. Thiemann, R. Röhrig, und A. Günther, "Asynchronous Query Distribution Between Multiple i2b2 Research Data Warehouses: Li2b2-SHRINE" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 245, p. 1276.
    @incollection{Majeed.2017b, abstract = {Clinical Data Ware Houses are established sources for research and quality management. The open source data warehouse software i2b2 enjoys good reputation and wide-spread use in the international medical informatics community. We developed a novel infrastructure to allow queries to be distributed asynchronously between i2b2 data warehouses.},
      author = {Majeed, Raphael W. and St{\"o}hr, Mark R. and Thiemann, Volker and R{\"o}hrig, Rainer and G{\"u}nther, Andreas},
      title = {Asynchronous Query Distribution Between Multiple i2b2 Research Data Warehouses: Li2b2-SHRINE},
      pages = {1276},
      volume = {245},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29295361} }
  • [incollection] bibtex
    I. Seeger, A. Zeleke, M. H. Freitag, und R. Röhrig, "IT Infrastructure for Biomedical Research in North-West Germany" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 243, pp. 65-69.
    @incollection{Seeger.2017, abstract = {The efficient use of routine data for biomedical research presupposes an IT infrastructure designed for health care facilities. The objective of this study was to analyse which IT infrastructure is used in hospitals and by general practitioners' (GP) practices in the region Oldenburg-Bremen and to examine how well this supports research projects. To this end, IT managers and GPs were interviewed. The usage of hospital information systems (HIS) and data warehouse systems (DWS) in hospitals is of major importance for the study. Over 90 {\%} use DWS for administration, 42 {\%} for clinical research. None of the hospitals implemented consent for the use of routine data for research. Only a third of the GPs have participated in studies. The GPs' offices based EHR systems in use offer virtually no support for research projects. The study results demonstrate that technical and organisational measures are required for the further usage of routine data in the region.},
      author = {Seeger, Insa and Zeleke, Atinkut and Freitag, Michael H. and R{\"o}hrig, Rainer},
      title = {IT Infrastructure for Biomedical Research in North-West Germany},
      pages = {65--69},
      volume = {243},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28883172} }
  • [incollection] bibtex
    V. Thiemann, T. Xu, R. Röhrig, und R. W. Majeed, "Automated Report Generation for Research Data Repositories: From i2b2 to PDF" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 245, p. 1289.
    @incollection{Thiemann.2017, abstract = {We developed an automated toolchain to generate reports of i2b2 data. It is based on free open source software and runs on a Java Application Server. It is sucessfully used in an ED registry project. The solution is highly configurable and portable to other projects based on i2b2 or compatible factual data sources.},
      author = {Thiemann, Volker and Xu, Tingyan and R{\"o}hrig, Rainer and Majeed, Raphael W.},
      title = {Automated Report Generation for Research Data Repositories: From i2b2 to PDF},
      pages = {1289},
      volume = {245},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29295374} }
  • [incollection] bibtex
    M. Wilken, D. Hüske-Kraus, A. Klausen, C. Koch, W. Schlauch, und R. Röhrig, "Alarm Fatigue: Causes and Effects" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 243, pp. 107-111.
    @incollection{Wilken.2017, abstract = {The term {\textquotedbl}Alarm fatigue{\textquotedbl} is commonly used to describe the effect which a high number of alarms can have on caregivers: Frequent alarms, many of which are avoidable, can lead to inadequate responses, severely impacting patient safety. In the first step of a long-term effort to address this problem, both the direct and indirect impact of alarms, as well as possible causes of unnecessary alarms were focused. Models of these causes and impacts were developed using a scoping review which included guided interviews with experts from medical informatics, clinicians and medical device manufacturers. These models can provide the methodical grounds for the definition of targeted interventions and the assessment of their effects.},
      author = {Wilken, Marc and H{\"u}ske-Kraus, Dirk and Klausen, Andreas and Koch, Christian and Schlauch, Wolfgang and R{\"o}hrig, Rainer},
      title = {Alarm Fatigue: Causes and Effects},
      pages = {107--111},
      volume = {243},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/28883181} }
  • [incollection] bibtex
    T. Xu, V. Thiemann, R. Röhrig, D. Brammen, und R. W. Majeed, "Secure Electronical Communications and Data Transfers in a Clinical Environment" in German Medical Data Sciences: Visions and Bridges, Röhrig, R., Timmer, A., Binder, H., und Sax, U., Eds., IOS Press, 2017, vol. 245, p. 1315.
    @incollection{Xu.2017, abstract = {As part of the German Project AKTIN, data security arises as an important issue. The context of this issue was detailed and the requirements were determined, with special focus on the hospital's point of view. The solution is illustrated in this poster. Further use cases in other medical or study context are also discussed.},
      author = {Xu, Tingyan and Thiemann, Volker and R{\"o}hrig, Rainer and Brammen, Dominik and Majeed, Raphael W.},
      title = {Secure Electronical Communications and Data Transfers in a Clinical Environment},
      pages = {1315},
      volume = {245},
      publisher = {{IOS Press}},
      isbn = {978-1-61499-807-5},
      series = {Studies in Health Technology and Informatics},
      editor = {R{\"o}hrig, Rainer and Timmer, Antje and Binder, H and Sax, Ulrich},
      booktitle = {German Medical Data Sciences: Visions and Bridges},
      year = {2017},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29295398} }
  • [article] bibtex
    N. Dragano, K. Geffert, B. Geisel, T. Hartmann, F. Hoffmann, S. Schneider, M. Voss, und A. Gerhardus, "[Education and Training in Public Health - Results of the Working Group 9 of the Forum Future Public Health, Berlin 2016]" Das Gesundheitswesen, vol. 79, iss. 11, pp. 929-931, 2017.
    @article{Dragano.2017, abstract = {The need for a qualified public health workforce can only be met by appropriate provision of a wide spectrum of basic, advanced and continuing education and training programs on public health that meet international standards. At the same time, efforts must be made to offer young academics attractive career opportunities. Training in public health competences must also be provided for allied professionals in health care and for professions with influence on the determinants of health such as urban planning or agricultural science. This report from a working group meeting at the 'Public Health Zukunftsforum 2016' in Berlin presents ideas for the further development of training in public health in Germany.},
      author = {Dragano, N. and Geffert, K. and Geisel, B. and Hartmann, T. and Hoffmann, Falk and Schneider, S. and Voss, M. and Gerhardus, A.},
      year = {2017},
      title = {[Education and Training in Public Health - Results of the Working Group 9 of the Forum Future Public Health, Berlin 2016]},
      keywords = {Biomedical Technology/trends;Computer Communication Networks/trends;Computers/trends;Forecasting;Germany;Humans;Interdisciplinary Communication;Internationality;Intersectoral Collaboration;National Health Programs/*trends;Precision Medicine/trends;Public Health/*education/trends},
      pages = {929--931},
      volume = {79},
      number = {11},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Lehre, Fort- und Weiterbildung in Public Health.},
      doi = {10.1055/s-0043-119358},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/29172221} }
  • [inproceedings] bibtex
    R. Eckert, S. M. Müller, S. Glende, A. Hein, und R. Welge, "LivingCare - An autonomously learning, human centered home automation system: Collection and preliminary analysis of a large dataset of real living situations" in Proc. Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016, Cham, 2017, pp. 549-557.
    @inproceedings{Eckert.2017, abstract = {Within the scope of LivingCare, a BMBF funded research project, a real senior residence was equipped with a large amount of home automation sensors. More than sixty sensors and actuators were installed in this apartment. This automa-tion system is working totally passive in the background. It doesn't perform any actions. All actions performed by hu-mans like switching light on or off, setting the temperature and the usage of electric devices like TVs will only be recorded as data and not performed by the system. This data is collected over a period of 18 months. Thus, one of the largest mobility and characteristics datasets based on home automation sensors will be acquired. This data will be the foundation for developing autonomously learning algorithms. During the second project phase these algorithms will start to control functions of the home automation system. The projects objective is to develop an autonomously learning home automation system that automatically adapts to the resident's behavior. The system will be able to grow with the users needs. With all the possible data collected it will be able to support daily actions, recognize behavior changes over timer and will be able to call help in emergency situations.},
      author = {Eckert, Ralf and M{\"u}ller, Sebastian Matthias and Glende, Sebastian and Hein, Andreas and Welge, Ralph},
      title = {LivingCare - An autonomously learning, human centered home automation system: Collection and preliminary analysis of a large dataset of real living situations},
      keywords = {autonomously learning;field trail;home automation;Informationenfehlen DOI;Internet of Things;IoT;real life data;reinforcement learning},
      pages = {549--557},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-319-52321-7},
      series = {Advanced Technologies and Societal Change},
      editor = {Wichert, Reiner and Mand, Beate},
      booktitle = {Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016},
      year = {2017},
      address = {Cham},
      file = {Eckert et al. - 2016 - LivingCare - An autonomously learning, human centered home automation system Collection and preliminary analysis:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Eckert et al. - 2016 - LivingCare - An autonomously learning, human centered home automation system Collection and preliminary analysis.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    S. Hellmers, E. Steen, L. Dasenbrock, A. Heinks, J. Bauer, S. Fudickar, und A. Hein, "Towards a minimized unsupervised technical assessment of physical performance in domestic environments" in Proc. Proceedings of the 11th EAI International Conference on Pervasive Computing Technologies for Healthcare - PervasiveHealth '17, New York, New York, USA, 2017, pp. 207-216.
    @inproceedings{Hellmers.2017, abstract = {Early detection of changes in mobility associated with functional decline can increase the therapeutic success by prolonging self-determined living. To get an unbiased and high frequently status of the physical performance of the persons at risk, unsupervised assessments of their functional abilities should ideally take place in their homes.$\backslash$r$\backslash$nThus, we have developed a minimized unsupervised technical assessment of physical performance in domestic environments.$\backslash$r$\backslash$nBy conducting an exploratory factor analysis, based on the results of 79 study participants with a minimum age of 70 years, we could clarify that common assessment items mainly represent three key parameters of functional performance$\backslash$r$\backslash$nmobility and endurance, strength and balance. Consequently, we identified a minimal set of assessment items that is suitable for home-assessments and that, since covering all three parameters, is able to generate clinical meaningful and relevant insights about the functional status. Regarding the parameter mobility, we developed a technical assessment of physical performance for domestic environments, which utilizes short distance walk times assessed via ambient presence sensors as an indicator for potential functional decline. In a field trial over ten months with 20 participants with a mean age of 84.25 years, we could confirm the general feasibility of our approach and the proposed system.},
      author = {Hellmers, Sandra and Steen, Enno-Edzard and Dasenbrock, Lena and Heinks, Andrea and Bauer, J{\"u}rgen and Fudickar, Sebastian and Hein, Andreas},
      title = {Towards a minimized unsupervised technical assessment of physical performance in domestic environments},
      url = {http://dl.acm.org/citation.cfm?doid=3154862.3154882},
      keywords = {accepted;full paper;UNIAMT},
      pages = {207--216},
      publisher = {{ACM Press}},
      isbn = {9781450363631},
      booktitle = {Proceedings of the 11th EAI International Conference on Pervasive Computing Technologies for Healthcare - PervasiveHealth '17},
      year = {2017},
      address = {New York, New York, USA},
      doi = {10.1145/3154862.3154882},
      file = {Hellmers et al. - 2017 - Towards a minimized unsupervised technical assessment of physical performance in domestic environments:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2017 - Towards a minimized unsupervised technical assessment of physical performance in domestic environments.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    S. Hellmers, S. Fudickar, E. Lange, C. Lins, und A. Hein, "Validation of a motion capture suit for clinical gait analysis" in Proc. Proceedings of the 11th EAI International Conference on Pervasive Computing Technologies for Healthcare - PervasiveHealth '17, New York, New York, USA, 2017, pp. 120-126.
    @inproceedings{Hellmers.2017b, abstract = {Gait analysis is often supported by technology. Due to limitations in optical systems, such as limited measurement volumes and the requirement of a laboratory environment, low-cost inertial measurement unit (IMU) based motion capture system might be better suited for gait analysis since they involve no spatial limitations and are flexible applicable. In this paper we investigate, if a low-cost IMU-based motion capture suits are an adequate alternative for clinical gait analysis in terms of accuracy of the determination of joint flexions and gait parameters. For this reason, we developed a gait analysis system and a gait analysis algorithm, which detects joint positions based on the Joint Coordinate System and determines knee, hip, and ankle flexions, as well as spatiotemporal parameters such as the number of steps, cadence, step duration and step length, and the specific gait phases. We evaluated and validated the IMU-based system in comparison to camera-based measurements (as gold standard) with three different healthy adult subjects. The evaluation indicates that the full-body motion capture system achieves a high degree of precision (0.86) and recall (0.98) in the recognition of gait cycles. The harmonic mean F(0.15) of the two factors precision and recall is on average 0.96 and the mentioned temporal gait parameters can be determined with an error below 10 ms. The mean derivation in the determination of joint angles amounts 1.35+-2°. Consequently, the article at hand indicates that low-cost IMU-based motion capture suits are an accurate alternative for gait analysis.},
      author = {Hellmers, Sandra and Fudickar, Sebastian and Lange, Eugen and Lins, Christian and Hein, Andreas},
      title = {Validation of a motion capture suit for clinical gait analysis},
      url = {http://dl.acm.org/citation.cfm?doid=3154862.3154884},
      keywords = {accepted;full paper;UNIAMT},
      pages = {120--126},
      publisher = {{ACM Press}},
      isbn = {9781450363631},
      booktitle = {Proceedings of the 11th EAI International Conference on Pervasive Computing Technologies for Healthcare - PervasiveHealth '17},
      year = {2017},
      address = {New York, New York, USA},
      doi = {10.1145/3154862.3154884},
      file = {Hellmers et al. - 2017 - Validation of a motion capture suit for clinical gait analysis:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2017 - Validation of a motion capture suit for clinical gait analysis.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    S. Hellmers, S. Fudickar, L. Dasenbrock, A. Heinks, J. Bauer, und A. Hein, "Understanding Jump Landing as an Oscillating System: A Model-based Approach of Balance and Strength Analyses" in Proc. Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies, Porto, 2017, pp. 159-168.
    @inproceedings{Hellmers.2017c, abstract = {Counter movement jumps (CMJ) are well-suited to measure the muscle power and balance. Since it has been clarified that well accepted CMJ amplification-based balance measures (such as TTS or CoP) are significantly influenced by algorithmic and measurement settings and thus, measurement results have limited meaningfulness among force platforms, we introduce a new model-based approach measuring the postural stability. In this, during the landing and recovery phases after vertical jumps, the lower extremities can be represented by an oscillating system and the corresponding transfer function is described by a second-order delay (PT2) element. In an initial prospective study with 20 subjects aged over 70 years, we observed an inverse relationship between the natural frequency and the jump height and could also identify an influence of sex, and body weight on the jump height. Furthermore, we also found a strong relation between natural frequency and dynamic postural stability index (DPSI), even though these results must be statistically ensured statistically using a larger cohort, due to the current limited number of subjects. Nevertheless, we could confirm the general applicability of the Systems and Control Technology perspective on describing human movements in a potentially more robust manner than current amplification based approaches.},
      author = {Hellmers, Sandra and Fudickar, Sebastian and Dasenbrock, Lena and Heinks, Andrea and Bauer, J{\"u}rgen and Hein, Andreas},
      title = {Understanding Jump Landing as an Oscillating System: A Model-based Approach of Balance and Strength Analyses},
      url = {http://www.scitepress.org/DigitalLibrary/PublicationsDetail.aspx?ID=HGfliCWA5Hs%3D http://www.scitepress.org/DigitalLibrary/Link.aspx?doi=10.5220/0006171101590168},
      keywords = {accepted;full paper;UNIAMT},
      pages = {159--168},
      publisher = {{SCITEPRESS - Science and Technology Publications}},
      isbn = {978-989-758-213-4},
      booktitle = {Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies},
      year = {2017},
      address = {Porto},
      doi = {10.5220/0006171101590168},
      file = {Hellmers et al. - 2017 - Understanding Jump Landing as an Oscillating System A Model-based Approach of Balance and Strength Analyses:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2017 - Understanding Jump Landing as an Oscillating System A Model-based Approach of Balance and Strength Analyses.pdf:pdf} }
  • [incollection] bibtex | Dokument aufrufen Dokument aufrufen
    R. Eckert, S. M. Müller, S. Glende, A. Gerka, A. Hein, und R. Welge, "LivingCare---An Autonomously Learning, Human Centered Home Automation System: Collection and Preliminary Analysis of a Large Dataset of Real Living Situations" in Ambient Assisted Living. Advanced Technologies and Societal Change, Wichert, R. und Mand, B., Eds., Cham: Springer, 2017, vol. 426, pp. 55-72.
    @incollection{Eckert.2017b, abstract = {Within the scope of LivingCare, a BMBF funded research project, a real senior residence was equipped with a large amount of home automation sensors. More than sixty sensors and actuators were installed in this apartment. All actions performed by humans like switching light on or off, setting the temperature and the usage of electric devices like TVs will be recorded. This data is collected over a period of 18 months. Thus, one of the largest mobility and characteristics datasets based on home automation sensors will be acquired. This data will be the foundation for developing autonomously learning algorithms. During the second project phase these algorithms will start to control functions of the home automation system. The project's objective is to develop an autonomously learning home automation system that automatically adapts to the residents' behavior. The system will be able to grow with the users' needs. With all the possible data collected it will be able to support daily actions, recognize behavior changes over time and will be able to call help in emergency situations.},
      author = {Eckert, Ralf and M{\"u}ller, Sebastian Matthias and Glende, Sebastian and Gerka, Alexander and Hein, Andreas and Welge, Ralph},
      title = {LivingCare---An Autonomously Learning, Human Centered Home Automation System: Collection and Preliminary Analysis of a Large Dataset of Real Living Situations},
      url = {http://link.springer.com/10.1007/978-3-319-54283-6},
      keywords = {Gait Speed;Movement Sensor;Occupation Time;Sensor Event;Test Person},
      pages = {55--72},
      volume = {426},
      publisher = {Springer},
      isbn = {978-3-319-54282-9},
      editor = {Wichert, Reiner and Mand, Beate},
      booktitle = {Ambient Assisted Living. Advanced Technologies and Societal Change},
      year = {2017},
      address = {Cham},
      doi = {10.1007/978-3-319-54283-6},
      file = {Eckert et al. - 2017 - LivingCare—An Autonomously Learning, Human Centered Home Automation System Collection and Preliminary Analysis of:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Eckert et al. - 2017 - LivingCare—An Autonomously Learning, Human Centered Home Automation System Collection and Preliminary Analysis of.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    A. Gerka, M. Eichelberg, N. Abmeier, M. Schwarz, S. Brinkmann-Gerdes, und A. Hein, "QuoVadis -- Definition of Requirements and Conception for Interconnected Living in a Quarter for Dementia Patients" in Proc. Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016, Cham, 2017, pp. 27-39.
    @inproceedings{Gerka.2017b, abstract = {The determination of a suitable living and care arrangement for dementia patients is a difficult decision for the patients themselves and their relatives. This decision becomes even more difficult if only classical arrangements are considered. Such arrangements, like care in long term care facilities or care in the own apartment applied by the relatives, often do not address the needs of dementia patients appropriately or cause significant stress for the relatives. Therefore, a new liv-ing arrangement concept is developed in the research project QuoVadis, which is called ``interconnected living in the quarter''. In this new living arrangement dementia patients can stay in their own accommodation while they are integrat-ed into a care concept at the same time. In a quarter, a ``quarter manager'' is responsible for organizing care and help for the dementia patients. To empower the quarter manager to support the residents, an intelligent sensor-based system is developed. This system will be integrated into the apartments of the dementia patients. This article presents the require-ments definition for the technical system. Furthermore, a concept to fulfil these requirements is presented. In this con-cept, an adaptive decision support system (ADSS) will be presented.},
      author = {Gerka, Alexander and Eichelberg, Marco and Abmeier, Nadine and Schwarz, Marie-Luise and Brinkmann-Gerdes, Stefanie and Hein, Andreas},
      title = {QuoVadis -- Definition of Requirements and Conception for Interconnected Living in a Quarter for Dementia Patients},
      url = {https://www.vde-verlag.de/proceedings-en/454212078.html http://link.springer.com/10.1007/978-3-319-52322-4},
      keywords = {Informationenfehlen},
      pages = {27--39},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-319-52321-7},
      series = {Advanced Technologies and Societal Change},
      editor = {Wichert, Reiner and Mand, Beate},
      booktitle = {Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016},
      year = {2017},
      address = {Cham},
      doi = {10.1007/978-3-319-52322-4},
      file = {Gerka et al. - 2017 - QuoVadis – Definition of Requirements and Conception for Interconnected Living in a Quarter for Dementia Patients:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2017 - QuoVadis – Definition of Requirements and Conception for Interconnected Living in a Quarter for Dementia Patients.pdf:pdf} }
  • [article] bibtex
    Dominik Gregor Brammen, Felix Walcher, Heike Dewenter, Sylvia Thun, Kai Heitmann, Raphael W. Majeed, Rolf Lefering, Sebastian Claudius Semler, und Rainer Röhrig, "Entwicklung eines dezentralisierten Notaufnahmeregisters auf Basis von e-Health-Standards" e-Health Solingen : medical-future-Verl. (2015), p. 29-33 <29-33, 2016.
    @article{DominikGregorBrammen.2016,
      author = {{Dominik Gregor Brammen} and {Felix Walcher} and {Heike Dewenter} and {Sylvia Thun} and {Kai Heitmann} and {Raphael W. Majeed} and {Rolf Lefering} and {Sebastian Claudius Semler} and {Rainer R{\"o}hrig}},
      year = {2016},
      title = {Entwicklung eines dezentralisierten Notaufnahmeregisters auf Basis von e-Health-Standards},
      journal = {e-Health Solingen : medical-future-Verl. (2015), p. 29-33 {\textless}29-33} }
  • [article] bibtex
    Heike Dewenter, Sylvia Thun, Dominik Gregor Brammen, Felix Walcher, H. Kai Uwe, Rolf Lefering, Sebastian Claudius Semler, und Rainer Röhrig, "Chancen einer Referenzterminologienutzung innerhalb des deutschen Gesundheitswesens : Erkenntnisse aus dem Forschungsprojekt AKTIN" e-Health Solingen : medical-future-Verl. (2015), p. 88-91 <88-91, 2016.
    @article{HeikeDewenter.2016,
      author = {{Heike Dewenter} and {Sylvia Thun} and {Dominik Gregor Brammen} and {Felix Walcher} and {Kai Uwe},
      Heitmann and {Rolf Lefering} and {Sebastian Claudius Semler} and {Rainer R{\"o}hrig}},
      year = {2016},
      title = {Chancen einer Referenzterminologienutzung innerhalb des deutschen Gesundheitswesens : Erkenntnisse aus dem Forschungsprojekt AKTIN},
      journal = {e-Health Solingen : medical-future-Verl. (2015), p. 88-91 {\textless}88-91} }
  • [article] bibtex
    Marius Merz, Rainer Röhrig, Markus A. Weigand, und Valesco Wladimir Mann, "Larynxmaske" Notfalltechniken Schritt für Schritt Stuttgart : Georg Thieme Verlag (2016), p. 57-71 <57-71, 2016.
    @article{MariusMerz.2016,
      author = {{Marius Merz} and {Rainer R{\"o}hrig} and {Markus A. Weigand} and {Valesco Wladimir Mann}},
      year = {2016},
      title = {Larynxmaske},
      journal = {Notfalltechniken Schritt f{\"u}r Schritt Stuttgart : Georg Thieme Verlag (2016), p. 57-71 {\textless}57-71} }
  • [article] bibtex
    Corinna Feeken, Dag Ennenga, Merlin Wassmann, Heiko Müller, Wilko Heuten, und Susanne Boll, "ClimbingAssist - direct vibro-tactile feedback on climbing technique" Proceedings of the 2016 ACM International Joint Conference on Pervasive and Ubiquitous Computing : Adjunct : September 12- 16, 2016, Heidelberg, Germany New York, NY : ACM (2016), p. 57-60 <57-60, p. online-ressource, 2016.
    @article{CorinnaFeeken.2016,
      author = {{Corinna Feeken} and {Dag Ennenga} and {Merlin Wassmann} and {Heiko M{\"u}ller} and {Wilko Heuten} and {Susanne Boll}},
      year = {2016},
      title = {ClimbingAssist - direct vibro-tactile feedback on climbing technique},
      pages = {Online-Ressource},
      journal = {Proceedings of the 2016 ACM International Joint Conference on Pervasive and Ubiquitous Computing : Adjunct : September 12- 16, 2016, Heidelberg, Germany New York, NY : ACM (2016), p. 57-60 {\textless}57-60},
      doi = {10.1145/2968219.2971417{\$}{\$}Elinktorsrc} }
  • [article] bibtex
    Elizabeth Borycki, J. W. Dexheimer, Carola Hullin L., Y. Gong, J. Stefanie, Jari Kaipio, S. Kennebeck, E. Kirkendall, K. Andre W., C. Kuziemsky, R. Marcilly, Rainer Röhrig, K. Saranto, Y. Senathirajah, J. Weber, und H. Takeda, "Methods for addressing technology-induced errors : the current state" Yearbook of medical informatics Stuttgart : Schattauer (2016), p. 30-40 <30-40, p. online-ressource, 2016.
    @article{ElizabethBorycki.2016,
      author = {{Elizabeth Borycki} and {J. W. Dexheimer} and {Carola Hullin L.} and {Y. Gong} and Stefanie, Jensen and {Jari Kaipio} and {S. Kennebeck} and {E. Kirkendall} and {Andre W.},
      Kushniruk and {C. Kuziemsky} and {R. Marcilly} and {Rainer R{\"o}hrig} and {K. Saranto} and {Y. Senathirajah} and {J. Weber} and {H. Takeda}},
      year = {2016},
      title = {Methods for addressing technology-induced errors : the current state},
      pages = {Online-Ressource},
      journal = {Yearbook of medical informatics Stuttgart : Schattauer (2016), p. 30-40 {\textless}30-40},
      doi = {10.15265/IY-2016-029} }
  • [article] bibtex
    Martin Oliver Kulla, Dominik Gregor Brammen, Felix Greiner, Anna Hörster, Rolf Lefering, Rajan Somasundaram, Christian Wrede, Rainer Röhrig, Bernadett Regina Erdmann, und Felix Walcher, "Vom Protokoll zum Register : Entwicklungen für ein bundesweites Qualitätsmanagement in deutschen Notaufnahmen = What do we need to assess the quality of care in German emergency departments? ; The development of a national data set, quality indicators and an emergency department registry by the DIVI" DIVI : Mitgliederzeitschrift der Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin (DIVI) Köln : Deutscher Ärzte-Verlag Vol. 7, No. 1 (2016), p. 12-19 7:1<12-19, p. online-ressource, 2016.
    @article{MartinOliverKulla.2016,
      author = {{Martin Oliver Kulla} and {Dominik Gregor Brammen} and {Felix Greiner} and {Anna H{\"o}rster} and {Rolf Lefering} and {Rajan Somasundaram} and {Christian Wrede} and {Rainer R{\"o}hrig} and {Bernadett Regina Erdmann} and {Felix Walcher}},
      year = {2016},
      title = {Vom Protokoll zum Register : Entwicklungen f{\"u}r ein bundesweites Qualit{\"a}tsmanagement in deutschen Notaufnahmen = What do we need to assess the quality of care in German emergency departments? ; The development of a national data set, quality indicators and an emergency department registry by the DIVI},
      pages = {Online-Ressource},
      journal = {DIVI : Mitgliederzeitschrift der Deutschen Interdisziplin{\"a}ren Vereinigung f{\"u}r Intensiv- und Notfallmedizin (DIVI) K{\"o}ln : Deutscher {\"A}rzte-Verlag Vol. 7, No. 1 (2016), p. 12-19 7:1{\textless}12-19},
      doi = {10.3238/DIVI.2016.0012-0020} }
  • Rainer Röhrig, Ralf Boldt, und Myriam Lipprandt, "Keine Wirkung ohne Nebenwirkung" Ehealthcom : Magazin für Health-IT, vernetzte Medizintechnik und Telemedizin Offenbach : Health-Care-Com (2016), 2/3, Seite S60-S63 2/3<60-63, p. online-ressource, 2016.
    @article{RainerRohrig.2016,
      author = {{Rainer R{\"o}hrig} and {Ralf Boldt} and {Myriam Lipprandt}},
      year = {2016},
      title = {Keine Wirkung ohne Nebenwirkung},
      url = {http://e-health-com.de/epaper/},
      pages = {Online-Ressource},
      journal = {Ehealthcom : Magazin f{\"u}r Health-IT, vernetzte Medizintechnik und Telemedizin Offenbach : Health-Care-Com (2016), 2/3, Seite S60-S63 2/3{\textless}60-63} }
  • [article] bibtex
    Tolga Philipp Naziyok, Atinkut Alamirrew Zeleke, und Rainer Röhrig, "Contactless patient monitoring for general wards : a systematic technology review" Exploring complexity in health : an interdisciplinary systems approach : proceedings of MIE2016 at HEC2016 Amsterdam : IOS Press (2016), p. 707-711 <707-711, p. online-ressource, 2016.
    @article{TolgaPhilippNaziyok.2016,
      author = {{Tolga Philipp Naziyok} and {Atinkut Alamirrew Zeleke} and {Rainer R{\"o}hrig}},
      year = {2016},
      title = {Contactless patient monitoring for general wards : a systematic technology review},
      pages = {Online-Ressource},
      journal = {Exploring complexity in health : an interdisciplinary systems approach : proceedings of MIE2016 at HEC2016 Amsterdam : IOS Press (2016), p. 707-711 {\textless}707-711},
      doi = {10.3233/978-1-61499-678-1-707} }
  • [article] bibtex
    Nils Lenz, Markus Hirschburger, Rainer Röhrig, Thilo Menges, Matthias Müller, Winfried Padberg, und Valesco Wladimir Mann, "Application of continuous wound-infusion catheters in lung transplantation : a retrospective data analysis" The thoracic and cardiovascular surgeon : official organ of the German Society for Thoracic and Cardiovascular Surgery Stuttgart : Thieme (4.4.2016), iss. Publikationsdatum: 04. April 2016 (eFirst), p. online-ressource, 2016.
    @article{NilsLenz.2016,
      author = {{Nils Lenz} and {Markus Hirschburger} and {Rainer R{\"o}hrig} and {Thilo Menges} and {Matthias M{\"u}ller} and {Winfried Padberg} and {Valesco Wladimir Mann}},
      year = {2016},
      title = {Application of continuous wound-infusion catheters in lung transplantation : a retrospective data analysis},
      pages = {Online-Ressource},
      number = {Publikationsdatum: 04. April 2016 (eFirst)},
      journal = {The thoracic and cardiovascular surgeon : official organ of the German Society for Thoracic and Cardiovascular Surgery Stuttgart : Thieme (4.4.2016)},
      doi = {10.1055/s-0036-1580621{\$}{\$}Elinktorsrc} }
  • L. Dasenbrock, T. Berg, S. Lurz, E. Beimforde, R. Diekmann, F. Sobotka, und J. Bauer, "The De Morton Mobility Index for evaluation of early geriatric rehabilitation" Zeitschrift für Gerontologie und Geriatrie, pp. 1-7, 2016.
    @article{Dasenbrock.2016,
      author = {Dasenbrock, Lena and Berg, T. and Lurz, S. and Beimforde, E. and Diekmann, Rebecca and Sobotka, F. and Bauer, J{\"u}rgen},
      year = {2016},
      title = {The De Morton Mobility Index for evaluation of early geriatric rehabilitation},
      url = {http://dx.doi.org/10.1007/s00391-016-1061-x https://link.springer.com/content/pdf/10.1007/s00391-016-1061-x.pdf},
      pages = {1--7},
      issn = {0948-6704},
      journal = {Zeitschrift f{\"u}r Gerontologie und Geriatrie},
      doi = {10.1007/s00391-016-1061-x} }
  • [article] bibtex
    A. Gerka, F. Lübeck, M. Eichelberg, und A. Hein, "Electricity Metering for Dementia Care State of the Art Activity Detection in QuoVadis" VDE Kongress 2016 - Internet der Dinge, pp. 1-6, 2016.
    @article{Gerka.2016, abstract = {Smart meters have been developed to improve the efficiency of metering procedures and to enable novel applications such as appliances making use of flexible tariffs based on the current availability of energy from renewable sources. This paper presents a novel application for smart meters in private households: The identification of health parameters and needs of dementia patients based on their usage of electrical appliances. The system presented in this paper aims at identifying odd behavior patterns of dementia patients. It improves the ability of a caretaker to identify long-term changes in the behavior of their patients. For this purpose, a smart meter, motion detectors and a water consumption sensor are installed in the flat of persons with dementia. The high sampling rate of the smart meter used in this setup ensures an accurate detection of electrical appliances in the flat. The data from the sensors is processed by machine learning algorithms on three levels. The system is developed and tested in the context of the QuoVadis research project.},
      author = {Gerka, Alexander and L{\"u}beck, Felix and Eichelberg, Marco and Hein, Andreas},
      year = {2016},
      title = {Electricity Metering for Dementia Care State of the Art Activity Detection in QuoVadis},
      keywords = {Informationenfehlen;OFFIS=AIT/AHT/QuoVadis},
      pages = {1--6},
      journal = {VDE Kongress 2016 - Internet der Dinge},
      file = {Gerka et al. - 2016 - Electricity Metering for Dementia Care State of the Art Activity Detection in QuoVadis:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2016 - Electricity Metering for Dementia Care State of the Art Activity Detection in QuoVadis.pdf:pdf} }
  • J. K. MacDonald, T. M. Nguyen, R. Khanna, und A. Timmer, "Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease" Cochrane Database Syst Rev, vol. 11, p. 007572, 2016.
    @article{MacDonald.2016,
      author = {MacDonald, John K. and Nguyen, T. M. and Khanna, Reena and Timmer, Antje},
      year = {2016},
      title = {Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease},
      url = {http://onlinelibrary.wiley.com/store/10.1002/14651858.CD007572.pub3/asset/CD007572.pdf?v=1&t=iwm4eljq&s=e5ef5dde373872a376e0b05d30b0c8e569b58db0},
      pages = {Cd007572},
      volume = {11},
      journal = {Cochrane Database Syst Rev},
      doi = {10.1002/14651858.CD007572.pub3} }
  • A. Timmer, P. H. Patton, N. Chande, J. W. McDonald, und J. K. MacDonald, "Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis" Cochrane Database Syst Rev, vol. 5, p. 000478, 2016.
    @article{Timmer.2016,
      author = {Timmer, Antje and Patton, P. H. and Chande, N. and McDonald, J. W. and MacDonald, John K.},
      year = {2016},
      title = {Azathioprine and 6-mercaptopurine for maintenance of remission in ulcerative colitis},
      url = {http://www.ncbi.nlm.nih.gov/pubmed/27192092},
      pages = {CD000478},
      volume = {5},
      journal = {Cochrane Database Syst Rev},
      doi = {10.1002/14651858.CD000478.pub4} }
  • A. L. Brütt, J. L. Magaard, S. Andreas, und H. Schulz, "A qualitative investigation of barriers and facilitators of rehabilitation success from the psychosomatic inpatients' perspective" Patient Preference and Adherence, vol. 10, pp. 1881-1888, 2016.
    @article{Brutt.2016,
      author = {Br{\"u}tt, Anna Levke and Magaard, J. L. and Andreas, S. and Schulz, H.},
      year = {2016},
      title = {A qualitative investigation of barriers and facilitators of rehabilitation success from the psychosomatic inpatients' perspective},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/27698554},
      pages = {1881--1888},
      volume = {10},
      issn = {1177-889X},
      journal = {Patient Preference and Adherence},
      doi = {10.2147/PPA.S108117} }
  • T. Kendrick, M. El-Gohary, B. Stuart, S. Gilbody, R. Churchill, L. Aiken, A. Bhattacharya, A. Gimson, A. L. Brütt, K. de Jong, und M. Moore, "Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults" Cochrane Database Syst Rev, vol. 7, iss. Art. No.: CD011119, p. 011119, 2016.
    @article{Kendrick.2016,
      author = {Kendrick, T. and El-Gohary, M. and Stuart, B. and Gilbody, S. and Churchill, R. and Aiken, L. and Bhattacharya, A. and Gimson, A. and Br{\"u}tt, Anna Levke and {de Jong},
      K. and Moore, M.},
      year = {2016},
      title = {Routine use of patient reported outcome measures (PROMs) for improving treatment of common mental health disorders in adults},
      url = {http://www.ncbi.nlm.nih.gov/pubmed/27409972},
      pages = {CD011119},
      volume = {7},
      number = {Art. No.: CD011119},
      journal = {Cochrane Database Syst Rev},
      doi = {10.1002/14651858.CD011119.pub2} }
  • [article] bibtex
    A. Klausen, R. Röhrig, und M. Lipprandt, "Feasibility of Eyetracking in Critical Care Environments - A Systematic Review" Studies in Health Technology and Informatics, vol. 228, pp. 604-608, 2016.
    @article{Klausen.2016, abstract = {Achieving a good understanding of the socio-technical system in critical or emergency situations is important for patient safety. Research in human-computer interaction in the field of anesthesia or surgery has the potential to improve usability of the user interfaces and enhance patient safety. Therefore eye-tracking is a technology for analyzing gaze patterns. It can also measure what is being perceived by the physician during medical procedures. The aim of this review is the applicability of eye-tracker in the domain of simulated or real environments of anesthesia, surgery or intensive care. We carried out a literature research in PubMed. Two independent researchers screened the titles and abstracts. The remaining 8 full-papers were analyzed based on the applicability of eye-trackers. The articles contain topics like training of surgeons, novice vs. experts or the cognitive workload. None of the publications address our goal. The applicability or limitations of the eye-tracker technology were stated incidentally.},
      author = {Klausen, Andreas and R{\"o}hrig, Rainer and Lipprandt, Myriam},
      year = {2016},
      title = {Feasibility of Eyetracking in Critical Care Environments - A Systematic Review},
      pages = {604--608},
      volume = {228},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27577455} }
  • [article] bibtex
    T. P. Naziyok, A. Zeleke, und R. Röhrig, "Contactless Patient Monitoring for General Wards: A Systematic Technology Review" Studies in Health Technology and Informatics, vol. 228, pp. 707-711, 2016.
    @article{Naziyok.2016, abstract = {INTRODUCTION Sudden, serious life-threatening situations happen even on general wards. Current technologies are working with sensors which are attached to every patient, which is a source of failures and false alarms. The goal of this review was to assess the state of the art of potential techniques for contactless patient monitoring in general wards. METHODS The MEDLINE database was used for literature retrieval. RESULTS 453 unique references screened, 34 research articles met inclusion criteria. Ballistocardiography, Radar and Thermography technologies are the most widely tested techniques. The Majority of the studies are done in a laboratory setting. No study shows the feasibility of one contactless monitoring technology over the distance required for monitoring rooms. CONCLUSION Today no technology is feasible. A combination of technologies may become feasible in 10 or more years, until then we have to think about ethical and privacy issues of these pervasive technologies.},
      author = {Naziyok, Tolga P. and Zeleke, Atinkut and R{\"o}hrig, Rainer},
      year = {2016},
      title = {Contactless Patient Monitoring for General Wards: A Systematic Technology Review},
      pages = {707--711},
      volume = {228},
      issn = {18798365},
      journal = {Studies in Health Technology and Informatics},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27577477} }
  • [article] bibtex
    U. Sax, M. Lipprandt, und R. Röhrig, "The Rising Frequency of IT Blackouts Indicates the Increasing Relevance of IT Emergency Concepts to Ensure Patient Safety" Yearbook of medical informatics, iss. 1, pp. 130-137, 2016.
    @article{Sax.2016, abstract = {INTRODUCTION As many medical workflows depend vastly on IT support, great demands are placed on the availability and accuracy of the applications involved. The cases of IT failure through ransomware at the beginning of 2016 are impressive examples of the dependence of clinical processes on IT. Although IT risk management attempts to reduce the risk of IT blackouts, the probability of partial/total data loss, or even worse, data falsification, is not zero. The objective of this paper is to present the state of the art with respect to strategies, processes, and governance to deal with the failure of IT systems. METHODS This article is conducted as a narrative review. RESULTS Worst case scenarios are needed, dealing with methods as to how to survive the downtime of clinical systems, for example through alternative workflows. These workflows have to be trained regularly. We categorize the most important types of IT system failure, assess the usefulness of classic counter measures, and state that most risk management approaches fall short on exactly this matter. CONCLUSION To ensure that continuous, evidence-based improvements to the recommendations for IT emergency concepts are made, it is essential that IT blackouts and IT disasters are reported, analyzed, and critically discussed. This requires changing from a culture of shame and blame to one of error and safety in healthcare IT. This change is finding its way into other disciplines in medicine. In addition, systematically planned and analyzed simulations of IT disaster may assist in IT emergency concept development.},
      author = {Sax, Ulrich and Lipprandt, Myriam and R{\"o}hrig, Rainer},
      year = {2016},
      title = {The Rising Frequency of IT Blackouts Indicates the Increasing Relevance of IT Emergency Concepts to Ensure Patient Safety},
      pages = {130--137},
      number = {1},
      journal = {Yearbook of medical informatics},
      doi = {10.15265/IY-2016-038},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5171553},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27830241} }
  • [article] bibtex
    G. Torbahn, H. Hofmann, R. Allert, M. H. Freitag, R. Dersch, V. Fingerle, H. Sommer, E. Motschall, J. J. Meerpohl, und C. Schmucker, "Efficacy and safety of pharmacological agents in the treatment of erythema migrans in early Lyme borreliosis-systematic review protocol" Systematic reviews, vol. 5, p. 73, 2016.
    @article{Torbahn.2016, abstract = {BACKGROUND Erythema migrans represents an early cutaneous and most common manifestation of Lyme borreliosis. Recommendations regarding pharmacological agents, dose and duration of treatment are subject of intense debate. This review aims to explore differences in efficacy and safety between pharmacological treatments and control treatment. METHODS To identify relevant studies, we will conduct a systematic literature search. We will include randomised controlled trials (RCTs) and non-RCTs. Eligible comparative studies need to (1) consider patients with a diagnosis of erythema migrans resulting from Lyme borreliosis and (2) compare different pharmacological agents against each other, against any other non-pharmacological treatment, placebo or no treatment. Two review authors will independently assess included studies for risk of bias according to the methods of the Cochrane Handbook for Systematic Reviews of Interventions and related to specific study designs. We will address patient-relevant outcomes including clinical remission of cutaneous symptoms, any treatment-related adverse events, quality of life and progressive symptoms such as neuroborreliosis or Lyme carditis and flu-like symptoms. Provided that the identified trials are comparable in terms of clinical issues, combined estimates will be provided. Estimations of treatment effects will be calculated based on a random effects model. Heterogeneity will be evaluated based on I (2) and chi-square test. In case of significant heterogeneity, a pooled estimate will not be provided, but heterogeneity will be investigated on the basis of methodological and clinical study aspects. We plan subgroup analysis to reveal potential differences in the effect estimates between patient populations and treatment specifications. We will consider risk of bias using sensitivity analyses to decide whether to rely on the pooled estimates. The quality of a body of evidence for individual outcomes will be assessed using the GRADE approach. DISCUSSION Benefits and harms of pharmacological treatment in erythema migrans have not yet been adequately assessed. This systematic review will evaluate and summarise available evidence addressing benefits and harms of different pharmacological treatments. In addition, this summary of clinical evidence will inform decision-making between clinicians and patients and will play an important part in patient care. SYSTEMATIC REVIEW REGISTRATION PROSPERO CRD42016037932.},
      author = {Torbahn, Gabriel and Hofmann, Heidelore and Allert, Roman and Freitag, Michael H. and Dersch, Rick and Fingerle, Volker and Sommer, Harriet and Motschall, Edith and Meerpohl, J{\"o}rg J. and Schmucker, Christine},
      year = {2016},
      title = {Efficacy and safety of pharmacological agents in the treatment of erythema migrans in early Lyme borreliosis-systematic review protocol},
      pages = {73},
      volume = {5},
      journal = {Systematic reviews},
      doi = {10.1186/s13643-016-0251-3},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27142846},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855495} }
  • R. H. Bakker, N. Riemersma, A. Brunner, S. Kappen, M. Buter, und J. Tuinstra, "Mantelzorg en Mindfulness" Tijdschrift voor gezondheidswetenschappen, vol. 94, iss. 1, pp. 16-19, 2016.
    @article{Bakker.2016,
      author = {Bakker, R. H. and Riemersma, N. and Brunner, A. and Kappen, S. and Buter, M. and Tuinstra, J.},
      year = {2016},
      title = {Mantelzorg en Mindfulness},
      url = {http://link.springer.com/article/10.1007%2Fs12508-016-0010-9 https://link.springer.com/article/10.1007/s12508-016-0010-9},
      pages = {16--19},
      volume = {94},
      number = {1},
      issn = {1388-7491},
      journal = {Tijdschrift voor gezondheidswetenschappen},
      doi = {10.1007/s12508-016-0010-9} }
  • A. Bartsch, M. Härter, J. Niedrich, A. L. Brütt, und A. Buchholz, "A Systematic Literature Review of Self-Reported Smoking Cessation Counseling by Primary Care Physicians" PLoS One, vol. 11, iss. 12, p. 0168482, 2016.
    @article{Bartsch.2016,
      author = {Bartsch, Anna-Lena and H{\"a}rter, Martin and Niedrich, J. and Br{\"u}tt, Anna Levke and Buchholz, Angela},
      year = {2016},
      title = {A Systematic Literature Review of Self-Reported Smoking Cessation Counseling by Primary Care Physicians},
      url = {https://www.ncbi.nlm.nih.gov/pubmed/28002498},
      pages = {e0168482},
      volume = {11},
      number = {12},
      issn = {1932-6203 (Electronic) 1932-6203 (Linking)},
      journal = {PLoS One},
      doi = {10.1371/journal.pone.0168482} }
  • [article] bibtex
    D. Brammen, V. Rickert, T. Esser, F. Prätsch, R. Röhrig, T. Hachenberg, und U. Ebmeyer, "Identifikation und ökonomische Bewertung von anästhesiologischen Nebendiagnosen auf Basis von intraoperativen Medikamentengaben" Der Anaesthesist, vol. 65, iss. 6, pp. 430-437, 2016.
    @article{Brammen.2016, abstract = {BACKGROUND Complications and comorbidities are encodable in the German diagnosis related groups (G-DRG) system and can improve revenues. In this study, secondary diagnoses were identified through drug administrations during anaesthesia and were economically evaluated by regrouping these cases. METHODS All intraoperative drug administrations from 2008 were extracted from a~database. After exclusion of synonyms and procedure-specific drug administrations, all remaining drugs were matched to explicit secondary diagnoses. All cases were regrouped with their newly defined secondary diagnoses by G{\hbox{-}}DRG grouper software, and changes in cost weight were evaluated. RESULTS A~total of 29~drugs could be assigned to 18~secondary diagnoses. From 22,440 anaesthesia the {\S}~21 data record could be extracted in 1,929 cases and was regrouped with 2,976 secondary diagnoses, according to additional proceeds of 125,330.25~{\text\euro} in 2008 and 103,542.35~{\text\euro} in 2014. Intraoperative secondary diagnoses influence cost weight only in small parts. The average increase in revenue in this study could have been about 50~{\text\euro} per case. From 2008 to 2014 secondary diagnoses were continuously devaluated, although some of them, e. g. afibrinogenemia, have were revaluated. DISCUSSION Our retrospective method of making a~diagnosis and assuming a~correct indication of drug administration is inapplicable to daily routine. The anaesthesiologic documentation has to make drug administration and thereby the secondary diagnosis plausible.},
      author = {Brammen, Dominik and Rickert, V. and Esser, T. and Pr{\"a}tsch, F. and R{\"o}hrig, Rainer and Hachenberg, Th and Ebmeyer, U.},
      year = {2016},
      title = {Identifikation und {\"o}konomische Bewertung von an{\"a}sthesiologischen Nebendiagnosen auf Basis von intraoperativen Medikamentengaben},
      pages = {430--437},
      volume = {65},
      number = {6},
      journal = {Der Anaesthesist},
      doi = {10.1007/s00101-016-0172-5},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27221390} }
  • A. L. Brütt, R. Buschmann-Steinhage, S. Kirschning, und K. Wegscheider, "Teilhabeforschung : Bedeutung, Konzepte, Zielsetzung und Methoden" Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz, vol. 59, iss. 9, pp. 1068-1074, 2016.
    @article{Brutt.2016b,
      author = {Br{\"u}tt, Anna Levke and Buschmann-Steinhage, R. and Kirschning, S. and Wegscheider, K.},
      year = {2016},
      title = {Teilhabeforschung : Bedeutung, Konzepte, Zielsetzung und Methoden},
      url = {http://www.ncbi.nlm.nih.gov/pubmed/27503496},
      pages = {1068--1074},
      volume = {59},
      number = {9},
      issn = {1437-1588 (Electronic) 1436-9990 (Linking)},
      journal = {Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz},
      doi = {10.1007/s00103-016-2403-y} }
  • [article] bibtex
    F. Heckel, J. Schlamelcher, H. Rotermund, M. Rockstroh, S. Zidowitz, und N. Thomas, "A service for monitoring the quality of intraoperative cone beam CT images" Current Directions in Biomedical Engineering, vol. 2, iss. 1, pp. 373-377, 2016.
    @article{Heckel.2016,
      author = {Heckel, Frank and Schlamelcher, Jan and Rotermund, Hanna and Rockstroh, Max and Zidowitz, Stephan and Thomas, Neumuth},
      year = {2016},
      title = {A service for monitoring the quality of intraoperative cone beam CT images},
      pages = {373--377},
      volume = {2},
      number = {1},
      issn = {2364-5504},
      journal = {Current Directions in Biomedical Engineering},
      doi = {10.1515/cdbme-2016-0161},
      file = {Heckel et al. - 2016 - A service for monitoring the quality of intraoperative cone beam CT images:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Heckel et al. - 2016 - A service for monitoring the quality of intraoperative cone beam CT images.pdf:pdf} }
  • A. Winter, R. D. Hilgers, R. Hofestadt, P. Knaup-Gregori, C. Ose, und A. Timmer, "Data Integration for Integrated Research and Care" Methods of information in medicine, vol. 55, iss. 4, pp. 365-366, 2016.
    @article{Winter.2016,
      author = {Winter, A. and Hilgers, R. D. and Hofestadt, R. and Knaup-Gregori, Petra and Ose, C. and Timmer, Antje},
      year = {2016},
      title = {Data Integration for Integrated Research and Care},
      url = {http://methods.schattauer.de/contents/archivestandard/issue/2382/manuscript/26056/download.html},
      pages = {365--366},
      volume = {55},
      number = {4},
      issn = {0026-1270},
      journal = {Methods of information in medicine},
      doi = {10.3414/me2016040001} }
  • [article] bibtex
    C. Bachmann, L. Aagaard, M. Burcu, G. Glaeske, L. J. Kalverdijk, I. Petersen, C. C. M. Schuiling-Veninga, L. P. Wijlaars, J. M. Zito, und F. Hoffmann, "Trends and patterns of antidepressant use in children and adolescents from five western countries, 2005-2012" Eur Neuropsychopharmacol, vol. 26, iss. 3, pp. 411-419, 2016.
    @article{Bachmann.2016, abstract = {Following the FDA black box warning in 2004, substantial reductions in antidepressant (ATD) use were observed within 2 years in children and adolescents in several countries. However, whether these reductions were sustained is not known. The objective of this study was to assess more recent trends in ATD use in youth (0-19 years) for the calendar years 2005/6-2012 using data extracted from regional or national databases of Denmark, Germany, the Netherlands, the United Kingdom (UK), and the United States (US). In a repeated cross-sectional design, the annual prevalence of ATD use was calculated and stratified by age, sex, and according to subclass and specific drug. Across the years, the prevalence of ATD use increased from 1.3{\%} to 1.6{\%} in the US data (+26.1{\%}); 0.7{\%} to 1.1{\%} in the UK data (+54.4{\%}); 0.6{\%} to 1.0{\%} in Denmark data (+60.5{\%}); 0.5{\%} to 0.6{\%} in the Netherlands data (+17.6{\%}); and 0.3{\%} to 0.5{\%} in Germany data (+49.2{\%}). The relative growth was greatest for 15-19 year olds in Denmark, Germany and UK cohorts, and for 10-14 year olds in Netherlands and US cohorts. While SSRIs were the most commonly used ATDs, particularly in Denmark (81.8{\%} of all ATDs), Germany and the UK still displayed notable proportions of tricyclic antidepressant use (23.0{\%} and 19.5{\%},
      respectively). Despite the sudden decline in ATD use in the wake of government warnings, this trend did not persist, and by contrast, in recent years, ATD use in children and adolescents has increased substantially in youth cohorts from five Western countries.},
      author = {Bachmann, C. and Aagaard, L. and Burcu, M. and Glaeske, G. and Kalverdijk, L. J. and Petersen, I. and Schuiling-Veninga, C. C. M. and Wijlaars, L. P. and Zito, J. M. and Hoffmann, Falk},
      year = {2016},
      title = {Trends and patterns of antidepressant use in children and adolescents from five western countries, 2005-2012},
      keywords = {Adolescent;Age Distribution;Antidepressant agents;Antidepressive Agents/*therapeutic use;Black box warning;Child;Child, Preschool;Depression/*drug therapy/*epidemiology;Europe/epidemiology;Female;Humans;Infant;Male;Multinational;Practice Patterns, Physicians'/*trends;Prevalence trends;Retrospective Studies;United States/epidemiology;Young Adult},
      pages = {411--419},
      volume = {26},
      number = {3},
      issn = {0924-977x},
      journal = {Eur Neuropsychopharmacol},
      doi = {10.1016/j.euroneuro.2016.02.001} }
  • [article] bibtex
    J. W. Dik, B. Sinha, A. W. Friedrich, J. R. Lo-Ten-Foe, R. Hendrix, R. Köck, B. Bijker, M. J. Postma, M. H. Freitag, G. Glaeske, und F. Hoffmann, "Cross-border comparison of antibiotic prescriptions among children and adolescents between the north of the Netherlands and the north-west of Germany" Antimicrob Resist Infect Control, vol. 5, p. 14, 2016.
    @article{Dik.2016, abstract = {BACKGROUND: Antibiotic resistance is a worldwide problem and inappropriate prescriptions are a cause. Especially among children, prescriptions tend to be high. It is unclear how they differ in bordering regions. This study therefore examined the antibiotic prescription prevalence among children in primary care between northern Netherlands and north-west of Germany. METHODS: Two datasets were used: The Dutch (IADB) comprises representative data of pharmacists in North Netherland and the German (BARMER GEK) includes nationwide health insurance data. Both were filtered using postal codes to define two comparable bordering regions with patients under 18~years for 2010. RESULTS: The proportion of primary care patients receiving at least one antibiotic was lower in northern Netherlands (29.8~{\%}; 95~{\%} confidence interval [95~{\%} CI]: 29.3-30.3), compared to north-west Germany (38.9~{\%}; 95~{\%} CI: 38.2-39.6). Within the respective countries, there were variations ranging from 27.0 to 44.1~{\%} between different areas. Most profound was the difference in second-generation cephalosporins: for German children 25~{\%} of the total prescriptions, while for Dutch children it was less than 0.1~{\%}. CONCLUSIONS: This study is the first to compare outpatient antibiotic prescriptions among children in primary care practices in bordering regions of two countries. Large differences were seen within and between the countries, with overall higher prescription prevalence in Germany. Considering increasing cross-border healthcare, these comparisons are highly valuable and help act upon antibiotic resistance in the first line of care in an international approach.},
      author = {Dik, J. W. and Sinha, B. and Friedrich, A. W. and Lo-Ten-Foe, J. R. and Hendrix, R. and K{\"o}ck, R. and Bijker, B. and Postma, M. J. and Freitag, Michael H. and Glaeske, G. and Hoffmann, Falk},
      year = {2016},
      title = {Cross-border comparison of antibiotic prescriptions among children and adolescents between the north of the Netherlands and the north-west of Germany},
      keywords = {Antibiotics;Border research;Germany;Health services research;Netherlands},
      pages = {14},
      volume = {5},
      issn = {2047-2994 (Print) 2047-2994},
      journal = {Antimicrob Resist Infect Control},
      doi = {10.1186/s13756-016-0113-8},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836103} }
  • [article] bibtex
    M. Dörks, G. Schmiemann, und F. Hoffmann, "Pro re nata (as needed) medication in nursing homes: the longer you stay, the more you get?" Eur J Clin Pharmacol, vol. 72, iss. 8, pp. 995-1001, 2016.
    @article{Dorks.2016, abstract = {PURPOSE: Injudicious pro re nata (PRN) or as needed prescribing can lead to polypharmacy, potentially harmful drug interactions and total drug doses exceeding the maximum recommended. Despite the known risks and the widespread administration, there is a paucity of current research examining the use of PRN drugs in nursing homes. Therefore, we examined characteristics of PRN drug use and potential predictors in nursing homes. METHODS: The multicentre cross-sectional study included a heterogeneous sample of 21 nursing homes in Northwestern Germany comprising 852 residents. Descriptive statistics and multivariable regression models were used to analyse and present the collected data. RESULTS: Nearly three quarters (74.9~{\%}) of all residents were treated with at least one PRN medication. On average, each resident was prescribed 2.5~$\pm$~2.3 PRN drugs. On average, residents with no PRN prescriptions stayed since 2.4~$\pm$~2.9~years in the nursing home. Residents with five and more PRN prescriptions were on average since 4.8~$\pm$~4.3~years in the nursing home. In a multivariable analysis, length of stay above the median of 2.1~years (OR 2.4; 95~{\%} CI 1.8, 3.2) and polypharmacy with five or more long-term drugs (OR 2.1; 95~{\%} CI 1.5, 2.9) were associated with a higher number of PRN prescriptions. Most commonly used PRN drug was acetaminophen, which was prescribed to 289 (33.9~{\%}) residents. CONCLUSIONS: The high prevalence of PRN medication should be taken into account when considering polypharmacy and inappropriate drug prescribing or using screening tools like the STOPP/START (screening tool of older persons' potentially inappropriate prescriptions/screening tool to alert doctors to right) criteria in nursing homes. Physicians should regularly reconsider the need of each PRN drug on the medication schedule. Moreover, the high prevalence of PRN medication and the association with length of stay highlights the importance of an accurate documentation.},
      author = {D{\"o}rks, Michael and Schmiemann, Guido and Hoffmann, Falk},
      year = {2016},
      title = {Pro re nata (as needed) medication in nursing homes: the longer you stay, the more you get?},
      keywords = {*nursing home;*Older people;*Polypharmacy;*Pro re nata (as needed) drug use;Aged;Aged, 80 and over;Cross-Sectional Studies;Drug Utilization/*statistics {\&} numerical data;Female;Germany;Humans;Inappropriate Prescribing/statistics {\&} numerical data;Length of Stay;Male;Nursing Homes/*statistics {\&} numerical data;Practice Patterns, Physicians'/*statistics {\&} numerical data},
      pages = {995--1001},
      volume = {72},
      number = {8},
      issn = {0031-6970},
      journal = {Eur J Clin Pharmacol},
      doi = {10.1007/s00228-016-2059-4} }
  • [article] bibtex
    M. Dörks, S. Herget-Rosenthal, G. Schmiemann, und F. Hoffmann, "Use of nonsteroidal anti-inflammatory drugs and renal failure in nursing home residents-results of the study \textquotedblInappropriate Medication in Patients with Renal Insufficiency in Nursing Homes\textquotedbl" Wien Klin Wochenschr, vol. 128, iss. 7-8, pp. 287-290, 2016.
    @article{Dorks.2016b, abstract = {BACKGROUND: Use of potentially inappropriate medications may result in increased morbidity, mortality and resource utilisation. Due to polypharmacy and age-related decline in renal function the elderly population is at particular risk. Therefore, the Beers Criteria include use of nonsteroidal anti-inflammatory drugs in chronic renal failure stage 4 and 5 as these drugs may worsen renal function. According to the summary of product characteristics, the nonsteroidal anti-inflammatory drugs ibuprofen and diclofenac are contraindicated in these patients. Objective was to assess the extent of nonsteroidal anti-inflammatory drug use in nursing homes with a focus on residents with severe renal failure. METHODS: Multi-centre cross-sectional study in 21 German nursing homes. The study population comprised residents for whom at least one serum creatinine value and information about sex were available, so that creatinine clearance rate could be estimated. RESULTS: In all, 685 of 852 residents were included as they fulfilled the abovementioned criteria. Renal failure was severe (estimated creatinine clearance rate {\textless} 30~ml/min) in 106 residents (15.5 {\%}). Approximately one-fifth was treated with at least one nonsteroidal anti-inflammatory drug in both the total study population (20.3 {\%}) and that with severe renal failure (20.8 {\%}). With one exception, all residents prescribed nonsteroidal anti-inflammatory drugs with severe renal failure were treated with at least one nonsteroidal anti-inflammatory drug that was contraindicated due to the underlying renal function. CONCLUSIONS: Notwithstanding their classification as potentially inappropriate medications and underlying contraindications, use of nonsteroidal anti-inflammatory drugs is common among nursing home residents with severe renal failure.},
      author = {D{\"o}rks, Michael and Herget-Rosenthal, Stefan and Schmiemann, Guido and Hoffmann, Falk},
      year = {2016},
      title = {Use of nonsteroidal anti-inflammatory drugs and renal failure in nursing home residents-results of the study {\textquotedbl}Inappropriate Medication in Patients with Renal Insufficiency in Nursing Homes{\textquotedbl}},
      keywords = {Aged;Aged, 80 and over;Anti-Inflammatory Agents, Non-Steroidal/*therapeutic use;Contraindicated use;Contraindications;Drug Utilization Review;Drug-Related Side Effects and Adverse Reactions/*epidemiology;Female;Germany/epidemiology;Homes for the Aged/*statistics {\&} numerical data;Humans;Inappropriate Prescribing/prevention {\&} control/*statistics {\&} numerical data;Kidney Function Tests/statistics {\&} numerical data;Male;NSAIDs;nursing home;Nursing Homes/*statistics {\&} numerical data;polypharmacy;Potentially inappropriate medications;Prevalence;Renal failure;Renal Insufficiency/diagnosis/*epidemiology;Risk Factors;Treatment Outcome},
      pages = {287--290},
      volume = {128},
      number = {7-8},
      issn = {0043-5325},
      journal = {Wien Klin Wochenschr},
      doi = {10.1007/s00508-015-0919-z} }
  • [article] bibtex
    F. Hoffmann, D. Boeschen, M. Dörks, S. Herget-Rosenthal, J. Petersen, und G. Schmiemann, "Renal Insufficiency and Medication in Nursing Home Residents. A Cross-Sectional Study (IMREN)" Deutsches Arzteblatt International, vol. 113, iss. 6, pp. 92-98, 2016.
    @article{Hoffmann.2016, abstract = {BACKGROUND: Nursing home residents often suffer from a multiplicity of medical conditions and take many different drugs. Many drugs are eliminated via the kidneys and thus require dose adjustment in patients with renal insufficiency. This is the first study to address the prevalence of renal insufficiency among nursing home residents in Germany, and the extent to which such persons take drugs that are contraindicated or incorrectly dosed because of renal insufficiency. METHODS: We carried out a cross-sectional study in nursing homes in the German regions of Bremen and Lower Saxony. Data were collected by nursing staff and given to us anonymously. Whenever the nursing home data did not include a current creatinine value, the patient's general practitioner was asked to supply this value. The estimated creatinine clearance (eCCr) was calculated with the Cockcroft-Gault formula. RESULTS: 852 residents of 21 nursing homes were included in the study; eCCr values were obtainable for 685 (80.4{\%}) of them (average age, 83.3 years; 75.2{\%} female). 48.2{\%} of these patients (95{\%} confidence interval [CI] 41.8-54.5) had moderate renal insufficiency (eCCr 59-30 mL/min), and 15.5{\%} (95{\%} CI 12.4-18.6) had severe renal insufficiency (eCCr {\textless}30 mL/min). 19.7{\%} were regularly taking at least one medication that was contraindicated or incorrectly dosed in the light of renal insufficiency. Predictors for such inappropriate drug use were advanced age, female sex, arterial hypertension, and polypharmacy. The drugs that were most often inappropriately used were metformin, ramipril, and potassium chloride. CONCLUSION: Nursing home residents often suffer from renal insufficiency and should therefore have their creatinine levels measured regularly. A knowledge of the creatinine level is a prerequisite for the proper adjustment of drug doses (if necessary). A practical and compact summary of dose-adjustment recommendations for patients with renal insufficiency would be desirable but is not yet available.},
      author = {Hoffmann, Falk and Boeschen, D. and D{\"o}rks, Michael and Herget-Rosenthal, Stefan and Petersen, J. and Schmiemann, Guido},
      year = {2016},
      title = {Renal Insufficiency and Medication in Nursing Home Residents. A Cross-Sectional Study (IMREN)},
      keywords = {Age Distribution;Aged;Aged, 80 and over;Comorbidity;Drug Utilization/statistics {\&} numerical data;Female;Germany/epidemiology;Homes for the Aged/*statistics {\&} numerical data;Humans;Hypertension/*epidemiology;Inappropriate Prescribing/*statistics {\&} numerical data;Male;Nursing Homes/*statistics {\&} numerical data;polypharmacy;Prevalence;Prognosis;Renal Insufficiency, Chronic/*drug therapy/*epidemiology;Risk Factors;Sex Distribution},
      pages = {92--98},
      volume = {113},
      number = {6},
      journal = {Deutsches Arzteblatt International},
      doi = {10.3238/arztebl.2016.0092},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782265},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/26931625} }
  • [article] bibtex
    F. Hoffmann und K. Allers, "Age and sex differences in hospitalisation of nursing home residents: a systematic review" BMJ open, vol. 6, iss. 10, p. 011912, 2016.
    @article{Hoffmann.2016b, abstract = {OBJECTIVES: Nursing home residents (NHRs) are frequently suffering from multimorbidity, functional and cognitive impairment, often leading to hospital admissions. Studies have found that male NHRs are more often hospitalised. The influence of age is inconclusive. We aimed to investigate the epidemiology of hospitalisations in NHRs, particularly focusing on age-specific and sex-specific differences. DESIGN: A systematic review was performed in PubMed, CINAHL and Scopus. Quality of studies was assessed. SETTING: Studies conducted in nursing homes were included. PARTICIPANTS: Nursing home residents. PRIMARY AND SECONDARY OUTCOMES: Outcome measures were the prevalence, incidence or duration of all-cause hospitalisation by age or sex. RESULTS: We identified 21 studies, 13 were conducted in the USA. The proportion of residents being hospitalised ranged across studies from 6.8{\%} to 45.7{\%} for various time periods of follow-up. A total of 20 studies assessed the influence of sex and found that hospitalisations are more often in male NHRs. A total of 16 studies conducted multivariate analyses and the OR of hospitalisation for males was between 1.22 and 1.67. Overall, 18 studies assessed the influence of age. Some studies showed an increasing proportion of admissions with increasing age, but several studies also found decreasing hospitalisations above the age of about 80-85 years. 8 of 13 studies conducting multivariate analyses included age as a continuous variable. Only 1 study reported stratified analyses by age and sex. 2 studies investigating primary causes of hospitalisation stratified by sex found some differences in main diagnoses. DISCUSSION: Male NHRs are more often hospitalised than females, but reasons for that are not well investigated. The influence of age is less clear, but there seems to be no clear linear relationship between age and the proportion being hospitalised. Further studies should investigate age and sex differences in frequencies and reasons for hospitalisation in NHRs.},
      author = {Hoffmann, Falk and Allers, Katharina},
      year = {2016},
      title = {Age and sex differences in hospitalisation of nursing home residents: a systematic review},
      keywords = {*Health services research;*hospitalisation;*Nursing Homes;*Systematic review;Accidental Falls/*statistics {\&} numerical data;Age Factors;Cardiovascular Diseases/*epidemiology;Comorbidity;Follow-Up Studies;Hospitalization/*statistics {\&} numerical data;Humans;Malnutrition/*epidemiology;Outcome Assessment, Health Care;polypharmacy;Prevalence;Sex Factors},
      pages = {e011912},
      volume = {6},
      number = {10},
      journal = {BMJ open},
      doi = {10.1136/bmjopen-2016-011912},
      file = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073589},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27855090} }
  • [article] bibtex
    D. Pieper, T. Mathes, R. Palm, und F. Hoffmann, "[How do authors of systematic reviews restrict their literature searches when only studies from Germany should be included?]" Z Evid Fortbild Qual Gesundhwes, vol. 117, pp. 1-8, 2016.
    @article{Pieper.2016, abstract = {INTRODUCTION: The use of search filters (e. g. for study types) facilitates the process of literature searching. Regional limits might be helpful depending on the research question. Regional search filters are already available for some regions, but not for Germany. Our aim is to give an overview of applied search strategies in systematic reviews (SRs) focusing on Germany. METHODS: We searched Medline (via Pubmed) applying a focused search strategy to identify SRs focusing on Germany in January 2016. Study selection and data extraction were performed by two reviewers independently. The search strategies with a focus on Germany were analyzed in terms of reasonableness and completeness relying on the Peer Review of Electronic Search Strategies (PRESS) criteria. A narrative evidence synthesis was performed. RESULTS: In total, 36 SRs (13 written in English) were included. 78{\%} were published in 2012 or later. The majority (89{\%}) of SRs utilized at least two different sources for their search with databases and checking references being the most common. 17 SRs did not use any truncations, ten SRs did not restrict their search to Germany, six SRs reported to have searched for German OR Germany. Only ten articles searched for the term Germany (occasionally jointly with the term Deutschland) without any use of an adjective such as German. DISCUSSION: There is a high interest in regionally focused SRs. The identified search strategies revealed a need for improvement. It would be helpful to develop a regional search filter for Germany that is able to identify studies performed in Germany.},
      author = {Pieper, Dawid and Mathes, T. and Palm, R. and Hoffmann, Falk},
      year = {2016},
      title = {[How do authors of systematic reviews restrict their literature searches when only studies from Germany should be included?]},
      keywords = {*medline;*Peer Review;*Review Literature as Topic;Databases, Factual;Deutschland;Germany;Humans;literature search;Literaturrecherche;Research Design;search filter;Suchfilter;systematic review;Systematische {\"U}bersichtsarbeit},
      pages = {1--8},
      volume = {117},
      issn = {1865-9217},
      journal = {Z Evid Fortbild Qual Gesundhwes},
      originalyear = {Wie beschr{\"a}nken Autoren systematischer Reviews ihre Literatursuchen, wenn nur Studien aus Deutschland eingeschlossen werden sollen?},
      doi = {10.1016/j.zefq.2016.08.007} }
  • [article] bibtex
    J. Schulze, R. Mazzola, und F. Hoffmann, "Incidence of Tube Feeding in 7174 Newly Admitted Nursing Home Residents With and Without Dementia" Am J Alzheimers Dis Other Demen, vol. 31, iss. 1, pp. 27-33, 2016.
    @article{Schulze.2016, abstract = {BACKGROUND: Tube feeding is a common form of long-term nutritional support, especially for nursing home residents, of whom many have dementia. OBJECTIVE: Estimating the incidence of feeding tube placement in nursing home residents with and without dementia. METHODS: Using claims data, we studied a cohort of newly admitted nursing home residents aged 65 years and older between 2004 and 2009. Analyses were stratified by dementia. We estimated incidence rates and performed multivariate Cox regression analyses. RESULTS: The study cohort included 7174 nursing home residents. Over a mean follow-up of 1.3 years, 273 people received a feeding tube. The incidence per 1000 person-years was 28.4, with higher estimates for patients with dementia. When adjusting for age, sex, and level of care as a time-dependent covariate, influence of dementia decreased to a nonsignificant hazard ratio. CONCLUSION: It seems that not dementia itself but the overall clinical condition might be a predictor of tube feeding placement.},
      author = {Schulze, J. and Mazzola, R. and Hoffmann, Falk},
      year = {2016},
      title = {Incidence of Tube Feeding in 7174 Newly Admitted Nursing Home Residents With and Without Dementia},
      keywords = {*Nursing Homes;Aged;Aged, 80 and over;Dementia;Dementia/*nursing;Enteral Nutrition/*statistics {\&} numerical data;feeding tube;Female;Health services research;Humans;incidence;Male;Malnutrition/epidemiology/prevention {\&} control;nursing home;Nursing home residents;Proportional Hazards Models;Severity of Illness Index},
      pages = {27--33},
      volume = {31},
      number = {1},
      issn = {1533-3175},
      journal = {Am J Alzheimers Dis Other Demen},
      doi = {10.1177/1533317515588180} }
  • [article] bibtex
    E. Swart, E. M. Bitzer, H. Gothe, M. Harling, F. Hoffmann, D. Horenkamp-Sonntag, B. Maier, S. March, T. Petzold, R. Röhrig, A. Rommel, T. Schink, C. Wagner, S. Wobbe, und J. Schmitt, "[A Consensus German Reporting Standard for Secondary Data Analyses, Version 2 (STROSA-STandardisierte BerichtsROutine fur SekundardatenAnalysen)]" Das Gesundheitswesen, vol. 78, iss. S 01, p. 161, 2016.
    @article{Swart.2016,
      author = {Swart, E. and Bitzer, Eva Maria and Gothe, H. and Harling, M. and Hoffmann, Falk and Horenkamp-Sonntag, Dirk and Maier, Birga and March, Stefanie and Petzold, T. and R{\"o}hrig, Rainer and Rommel, A. and Schink, Tania and Wagner, C. and Wobbe, S. and Schmitt, J.},
      year = {2016},
      title = {[A Consensus German Reporting Standard for Secondary Data Analyses, Version 2 (STROSA-STandardisierte BerichtsROutine fur SekundardatenAnalysen)]},
      pages = {e161},
      volume = {78},
      number = {S 01},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {STandardisierte BerichtsROutine fur Sekundardaten Analysen (STROSA) - ein konsentierter Berichtsstandard fur Deutschland, Version 2.},
      doi = {10.1055/s-0042-112008},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27428525} }
  • [article] bibtex
    M. Dörks, S. Herget-Rosenthal, G. Schmiemann, und F. Hoffmann, "Polypharmacy and Renal Failure in Nursing Home Residents: Results of the Inappropriate Medication in Patients with Renal Insufficiency in Nursing Homes (IMREN) Study" Drugs Aging, vol. 33, iss. 1, pp. 45-51, 2016.
    @article{Dorks.2016c, abstract = {BACKGROUND: Polypharmacy has become an emerging public health issue in recent years, since use of multiple medications or polypharmacy is beneficial for many conditions, but may also have negative effects like adverse drug reactions. The risk further increases in patients with chronic renal failure, a comorbidity very frequent in nursing home residents. Since more than 50{\%} of all drugs were renally excreted, dose adjustments in patients with renal failure are required. OBJECTIVE: To assess polypharmacy in German nursing homes, in particular in residents with renal failure. METHODS: Multi-center cross-sectional study in 21 nursing homes in Bremen and Lower Saxony/Germany. Baseline data were analysed using descriptive statistics. Multivariable logistic regression model and 95{\%} confidence intervals were used to study the association of renal failure and polypharmacy. RESULTS: Of all 852 residents, the analysis comprised those 685 with at least one serum creatinine value so that the estimated creatinine clearance could be calculated. Of those, 436 (63.6{\%}) had a severe or moderate renal failure, defined as estimated creatinine clearance {\textless}60 mL/min. Polypharmacy (5-9 drugs) was found in 365 (53.3{\%}) and excessive polypharmacy ({\textgreater}/=10 drugs) in 112 (16.4{\%}) residents. Diuretics and psycholeptics were the most commonly used drug classes. Severe renal failure (estimated creatinine clearance {\textless}30 mL/min) was associated with polypharmacy (OR: 2.8, 95{\%} CI 1.4-5.7). CONCLUSION: Both, polypharmacy and renal failure are common in German nursing home residents and an association of both could be found. Further studies are needed to assess the appropriateness of polypharmacy in these patients.},
      author = {D{\"o}rks, Michael and Herget-Rosenthal, Stefan and Schmiemann, Guido and Hoffmann, Falk},
      year = {2016},
      title = {Polypharmacy and Renal Failure in Nursing Home Residents: Results of the Inappropriate Medication in Patients with Renal Insufficiency in Nursing Homes (IMREN) Study},
      keywords = {*Polypharmacy;Aged;Aged, 80 and over;Comorbidity;Cross-Sectional Studies;Drug-Related Side Effects and Adverse Reactions/*epidemiology;Female;Germany;Humans;Male;Nursing Homes/*statistics {\&} numerical data;Renal Insufficiency/*epidemiology;Risk},
      pages = {45--51},
      volume = {33},
      number = {1},
      issn = {1179-1969 (Electronic) 1170-229X (Linking)},
      journal = {Drugs Aging},
      doi = {10.1007/s40266-015-0333-2},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/26659732} }
  • [article] bibtex
    F. Hoffmann und G. Schmiemann, "Pain medication in German nursing homes: a whole lot of metamizole" Pharmacoepidemiol Drug Saf, vol. 25, iss. 6, pp. 646-651, 2016.
    @article{Hoffmann.2016c, abstract = {PURPOSE: Prescribing of metamizole (dipyrone), an analgesic that has been withdrawn from the market or never approved in many countries owing to safety concerns, is high in elder persons in Germany. This study assessed the use of pain medications in German nursing homes with a special focus on prescribing patterns of metamizole. METHODS: Using data of the 'Inappropriate Medication in Patients with Renal Insufficiency in Nursing Homes' (IMREN) study conducted between October 2014 and April 2015 in nursing homes in Bremen and Lower Saxony, we studied prescribing of analgesics including both scheduled and as-needed medications. For residents with scheduled medication, dosage and duration of use were analysed. RESULTS: A total of 852 residents from 21 nursing homes were included. They were on average 83.5 years old, and 76.5{\%} were women; 73.8{\%} received at least one analgesic with 70.3{\%} obtaining World Health Organization step I drugs. The most frequently prescribed substances were metamizole (for 40.6{\%}) and paracetamol (acetaminophen; 35.6{\%}), with paracetamol given mostly as-needed. The proportion of residents receiving metamizole increased with age (up to 47.4{\%} in persons aged 90 years and over). Of 143 residents with scheduled metamizole (16.8{\%}), the mean daily dosage was 1843 mg (interquartile range [IQR]: 1500-2250); 66.9{\%} received metamizole for at least 90 days and 23.2{\%} for at least 365 days (mean duration 276 days; IQR: 59-314). DISCUSSION: There is a discrepancy between prescribing of metamizole for older persons, on the one hand, and evidence on comparative effectiveness and safety as well as approval and recommendations, on the other hand. Copyright (c) 2016 John Wiley {\&} Sons, Ltd.},
      author = {Hoffmann, Falk and Schmiemann, Guido},
      year = {2016},
      title = {Pain medication in German nursing homes: a whole lot of metamizole},
      keywords = {*analgesics;*dipyrone;*Germany;*Health services research;*Nursing Homes;*pharmacoepidemiology;Acetaminophen/administration {\&} dosage;Aged;Aged, 80 and over;Analgesics/*administration {\&} dosage;Cross-Sectional Studies;Dipyrone/*administration {\&} dosage;Dose-Response Relationship, Drug;Female;Germany;Homes for the Aged/statistics {\&} numerical data;Humans;Male;Nursing Homes/statistics {\&} numerical data;Pain/*drug therapy;Practice Patterns, Physicians'/*statistics {\&} numerical data},
      pages = {646--651},
      volume = {25},
      number = {6},
      issn = {1053-8569},
      journal = {Pharmacoepidemiol Drug Saf},
      doi = {10.1002/pds.3954},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/26748937} }
  • [article] bibtex
    F. Hoffmann, G. Schmiemann, und M. Dörks, "[Assessment of polypharmacy: A question of definition and underlying data]" Z Evid Fortbild Qual Gesundhwes, vol. 113, pp. 27-35, 2016.
    @article{Hoffmann.2016d, abstract = {BACKGROUND: Older persons are often subjected to polypharmacy. There is a large degree of variability in the definitions used, the underlying data sources and the medications included. Our aim was to analyse the influence of different definitions on the prevalence of polypharmacy. METHODS: We used data of the study {\textquotedbl}Inappropriate Medication in patients with REnal insufficiency in Nursing homes{\textquotedbl} (IMREN) conducted in nursing homes in Bremen and the surrounding area. Anonymised data were collected by nursing staff. Prescription drugs and over-the-counter drugs as well as scheduled and as-needed medications were assessed. RESULTS: 852 residents from 21 nursing homes were recruited (mean age: 83.5 years; 76.5{\%} female). Each resident received an average of 8.8 scheduled and as-needed medications, the prevalence of polypharmacy ({\textgreater}/=5 medications) was 83.5{\%}. When including scheduled medications only, residents received an average of 6.3 medications (polypharmacy 69.7{\%}). When restricting the analysis to prescription-only medicines, the results were comparable (6.3 medications per resident; polypharmacy 69.1{\%}). However, the two analyses included different drugs. A total of 74.3{\%} received at least one over-the-counter drug as scheduled medication (59.7{\%} on an as-needed basis). CONCLUSIONS: In studies investigating polypharmacy, the methods used should be reported in a transparent manner. This is particularly important when addressing the question of which drugs were included in the study.},
      author = {Hoffmann, Falk and Schmiemann, Guido and D{\"o}rks, Michael},
      year = {2016},
      title = {[Assessment of polypharmacy: A question of definition and underlying data]},
      keywords = {*Aging;*Patient Safety;*Polypharmacy;Aged, 80 and over;Arzneimitteltherapie;cross-sectional study;Female;Germany;Health services research;Humans;Male;nursing home;Nursing homes;Pflegeheim;pharmacotherapy;polypharmacy;Polypharmazie;Querschnittsstudie;Risk Factors;Risk Management;Versorgungsforschung},
      pages = {27--35},
      volume = {113},
      issn = {1865-9217},
      journal = {Z Evid Fortbild Qual Gesundhwes},
      originalyear = {Untersuchungen zu Polypharmazie: Eine Frage der Definition und der verwendeten Daten.},
      doi = {10.1016/j.zefq.2016.03.004},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27480186} }
  • [article] bibtex
    A. Luque Ramos, F. Hoffmann, J. Callhoff, A. Zink, und K. Albrecht, "Influenza and pneumococcal vaccination in patients with rheumatoid arthritis in comparison with age- and sex-matched controls: results of a claims data analysis" Rheumatol Int, vol. 36, iss. 9, pp. 1255-1263, 2016.
    @article{LuqueRamos.2016, abstract = {The aim of this study was to assess the vaccination status for influenza and pneumonia and the prevalence of hospitalised pneumonia in rheumatoid arthritis (RA) patients and population controls in Germany. Members of a large statutory health insurance fund in Germany who were continuously insured between 2009 and 2013 and had a diagnosis of RA in 2013 were age and sex matched 1:5 to members without RA. Pneumococcal and influenza vaccinations were evaluated with regard to age, sex and region of residence. Logistic regression models were used to determine predictors for influenza vaccination in RA patients. Prevalences of pneumonia that required hospitalisation were compared to regional vaccination rates. The data of 111,482 RA patients and 557,410 matched controls were available for analysis. Compared to controls, RA patients were vaccinated more frequently against influenza (40.8 vs. 32.2 {\%}) and pneumonia (15.0 vs. 10.0 {\%}). Vaccination rates increased with older age and differed between the federal states (highest in East Germany, lowest in South Germany). The region of residence, comorbidities, rheumatologic care and biologic treatment was associated with a higher probability of an influenza vaccination. Prevalences of pneumonia that required hospitalisation were 2-3 times higher in patients compared to controls and tended to be higher in regions with low vaccination rates. The increased pneumonia prevalence in RA patients confirms their status as a risk group. RA patients are vaccinated more frequently than controls, but vaccination rates are still low. The lower pneumonia prevalence in East Germany indicates that vaccination may help to reduce pneumonia in RA.},
      author = {{Luque Ramos},
      A. and Hoffmann, Falk and Callhoff, Johanna and Zink, Angela and Albrecht, Katinka},
      year = {2016},
      title = {Influenza and pneumococcal vaccination in patients with rheumatoid arthritis in comparison with age- and sex-matched controls: results of a claims data analysis},
      keywords = {Adolescent;Adult;Aged;Aged, 80 and over;Arthritis, Rheumatoid/*immunology;Databases, Factual;Female;Humans;Influenza;Influenza, Human/epidemiology/*prevention {\&} control;Male;Middle Aged;Pneumococcal Infections/epidemiology/*prevention {\&} control;Pneumonia;Prevalence;Rheumatoid arthritis;Vaccination;Vaccination/*statistics {\&} numerical data;Young Adult},
      pages = {1255--1263},
      volume = {36},
      number = {9},
      issn = {0172-8172},
      journal = {Rheumatol Int},
      doi = {10.1007/s00296-016-3516-1},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27372078} }
  • [article] bibtex
    N. Schmedt, B. Kollhorst, D. Enders, K. Jobski, J. Krappweis, E. Garbe, und T. Schink, "Comparative risk of death in older adults treated with antipsychotics: A population-based cohort study" Eur Neuropsychopharmacol, vol. 26, iss. 9, pp. 1390-1400, 2016.
    @article{Schmedt.2016, abstract = {Although the use of antipsychotics has been associated with an increased risk of death, data on the safety of individual substances is scarce. We thus aimed to compare the risk of death in new users of individual antipsychotics aged ={\textgreater}65 years and conducted a cohort study in the German Pharmacoepidemiological Research Database between 2005 and 2011. Patients were followed from initiation of treatment until death, 90 days after cohort entry, end of insurance or the end of the study period. Multivariable cox regression was used to estimate confounder adjusted hazard ratios (aHR) of death for 14 individual antipsychotics compared to risperidone. In sensitivity analyses, we also applied high-dimensional propensity score (HDPS) methods to explore possible unmeasured confounding. In a cohort of 137,713 new users of antipsychotics, a higher risk of death was found for haloperidol (aHR: 1.45; 95{\%} confidence interval: 1.35-1.55), levomepromazine (aHR: 1.34; 1.16-1.54), zuclopenthixol (aHR: 1.32; 1.02-1.72) and to a lesser extent for melperone (aHR: 1.13; 1.07-1.19) compared to risperidone. Lower risks were observed for quetiapine, prothipendyl, olanzapine, tiapride, clozapine, perazine and flupentixol. In subgroup analyses, levomepromazine and chlorprothixene were only associated with a higher risk of death in patients aged ={\textgreater}80 years and with dementia. The application of HDPS methods did not substantially change the results. In conclusion, our study suggests that initiation of haloperidol, levomepromazine, zuclopenthixol and chlorprothixene treatment is associated with an increased risk of death compared to risperidone and should be avoided in older patients except in palliative care when treatment alternatives are available.},
      author = {Schmedt, N. and Kollhorst, Bianca and Enders, D. and Jobski, Kathrin and Krappweis, J. and Garbe, E. and Schink, Tania},
      year = {2016},
      title = {Comparative risk of death in older adults treated with antipsychotics: A population-based cohort study},
      keywords = {*Adverse drug reaction;*Antipsychotic;*Death;*Dementia;*elderly;*Mortality;Age Factors;Aged;Aged, 80 and over;Antipsychotic Agents/*adverse effects/*therapeutic use;Dementia/drug therapy/mortality;Female;Follow-Up Studies;Germany;Humans;Male;Propensity Score;Proportional Hazards Models;Risk;Sex Factors},
      pages = {1390--1400},
      volume = {26},
      number = {9},
      issn = {0924-977x},
      journal = {Eur Neuropsychopharmacol},
      doi = {10.1016/j.euroneuro.2016.07.006},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27475994} }
  • [incollection] bibtex | Dokument aufrufen Dokument aufrufen
    R. Eckert, T. Frenken, N. Abmeier, A. Jüptner, und A. Hein, "Best Practice Beispiel zur Entwicklung des technisch-innovativen und von Nutzern akzeptierten Assistenzproduktes \glqqambiact\grqq - Tagungsbeiträge - VDE VERLAG" in Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015, Wichert, R. und Klausing, H., Eds., Springer International Publishing, 2016.
    @incollection{Eckert.2016, abstract = {Viele Forschungsarbeiten teilen dasselbe Schicksal, nach Abschluss der Forschungsarbeiten verschwinden sie in einer Schublade und werden vergessen. Die Gr{\"u}nde hierf{\"u}r sind vielf{\"a}ltig. H{\"a}ufig findet sich niemand, der die Idee weiterverfolgt und bereit ist ein Produkt aus dem Forschungsergebnis zu entwickeln oder es fehlt die Akzeptanz bei der Zielgruppe. Dieser Zustand w{\"a}re eventuell vermeidbar, wenn schon vor Beginn der Forschungsarbeit alle betroffenen Akteure eng zusammenarbeiten w{\"u}rden. Bei den Akuteren handelt es sich dabei nicht nur um Forscher, Firmen und Techniker, sondern speziell auch um die sp{\"a}tere Nutzergruppe. Nur wenn ein Produkt beim Anwender Akzeptanz findet kann daraus ein kommerzieller Erfolg werden. Besonders im Bereich AAL sind die meist {\"a}lteren Kunden skeptisch gegen{\"u}ber technischen Neurungen und lehne diese h{\"a}ufig ab. Anhand des Beispiels ambiact wird gezeigt, wie so eine enge Zusammenarbeit aussehen kann und so zu einer erfolgreichen Produktentwicklung beigetragen hat. Das Vorgehen deckt sich dabei mit den Paradigmen des Konzeptes von Responsible Research {\&} Inovation (RRI).},
      author = {Eckert, Ralf and Frenken, Thomas and Abmeier, Nadine and J{\"u}ptner, Alexander and Hein, Andreas},
      title = {Best Practice Beispiel zur Entwicklung des technisch-innovativen und von Nutzern akzeptierten Assistenzproduktes {\glqq}ambiact{\grqq} - Tagungsbeitr{\"a}ge - VDE VERLAG},
      url = {https://www.vde-verlag.de/proceedings-de/453901020.html},
      keywords = {Informationenfehlen},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-319-26345-8},
      series = {Advanced Technologies and Societal Change},
      editor = {Wichert, Reiner and Klausing, Helmut},
      booktitle = {Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015},
      year = {2016},
      file = {Eckert et al. - 2015 - Best Practice Beispiel zur Entwicklung des technisch-innovativen und von Nutzern akzeptierten Assistenzproduktes:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Eckert et al. - 2015 - Best Practice Beispiel zur Entwicklung des technisch-innovativen und von Nutzern akzeptierten Assistenzproduktes.pdf:pdf} }
  • [article] bibtex
    S. Hense, A. Luque Ramos, J. Callhoff, K. Albrecht, A. Zink, und F. Hoffmann, "[Prevalence of rheumatoid arthritis in Germany based on health insurance data : Regional differences and first results of the PROCLAIR study]" Z Rheumatol, vol. 75, iss. 8, pp. 819-827, 2016.
    @article{Hense.2016, abstract = {BACKGROUND: Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease with a prevalence of up to 1 {\%} in the adult population. OBJECTIVE: This study describes the prevalence of RA diagnoses in outpatient health insurance claims data, based on different case definitions and stratified by age, sex and region of residence. METHODS: Based on data from a nationwide statutory health insurance fund (BARMER GEK) from the year 2013, a cross-sectional study of insurants aged 18 years or older was conducted. The following case definitions were applied: A) a diagnosis of seropositive rheumatoid arthritis (M05) or other rheumatoid arthritis (M06) according to the international classification of diseases 10 German modification (ICD-10-GM) in at least two quarterly periods of the year 2013, B) case definition A plus determination of Creactive protein (CRP) or erythrocyte sedimentation rate (ESR) at least once, C) case definition B plus specific drug therapy and D) case definition A plus treatment by a rheumatologist. Raw as well as age and sex-standardized prevalences were calculated and stratified according to the federal state. RESULTS: The study population consisted of 7,155,315 insurants of whom 60.2 {\%} were female. Overall, RA prevalences for the respective case definitions were 1.62 {\%} (A), 1.11 {\%} (B), 0.94 {\%} (C) and 0.64 {\%} (D). When standardized to the German population the prevalences were 1.38 {\%} (A), 0.95 {\%} (B), 0.81 {\%} (C) and 0.55 {\%} (D). The proportion of women was approximately 80 {\%} for all case definitions. Prevalences increased with age, peaking in the age group 70-79 years old and showing the highest values in eastern and the lowest in southern Germany for raw as well as standardized measures. CONCLUSION: Regional differences in the prevalence of RA diagnoses in health insurance claims data were observed independent of age, sex and case definition. The expected prevalence according to the results of international studies was best achieved when case definitions with CRP or ESR were considered.},
      author = {Hense, S. and {Luque Ramos},
      A. and Callhoff, Johanna and Albrecht, Katinka and Zink, Angela and Hoffmann, Falk},
      year = {2016},
      title = {[Prevalence of rheumatoid arthritis in Germany based on health insurance data : Regional differences and first results of the PROCLAIR study]},
      keywords = {*epidemiology;*Health services research;*Healthcare insurance data;*rheumatoid arthritis;*Secondary data;Adolescent;Adult;Age Distribution;Aged;Ambulatory Care/*statistics {\&} numerical data;Arthritis, Rheumatoid/*diagnosis/economics/*epidemiology;Female;Germany/epidemiology;Humans;Male;Middle Aged;National Health Programs/*statistics {\&} numerical data;Population Surveillance/*methods;Prevalence;Risk Factors;Sex Distribution;Young Adult},
      pages = {819--827},
      volume = {75},
      number = {8},
      issn = {0340-1855},
      journal = {Z Rheumatol},
      originalyear = {Pravalenz der rheumatoiden Arthritis in Deutschland auf Basis von Kassendaten : Regionale Unterschiede und erste Ergebnisse der PROCLAIR-Studie.},
      doi = {10.1007/s00393-016-0088-0},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27120440} }
  • [article] bibtex
    J. Höfer, F. Hoffmann, G. Glaeske, und K. Sauer, "[Distal Forearm Fractures in Children and Adolescents: Frequency and Health Care Provision in Germany]" Das Gesundheitswesen, vol. 81, iss. 1, p. e1-e9, 2016.
    @article{Hofer.2016, abstract = {BACKGROUND: Despite their frequent occurrence, there are no standardized recommendations for treating distal forearm fractures in growing children. Due to the marked remodelling capacity, conservative therapy is the first choice treatment of fractures in children. However, there are concerns that the possibilities of conservative treatments are often underestimated. Information on the health care situation in Germany on this issue is scarce. METHODS: The present study is based on routine data of a German Health Insurance fund, the Gmunder ErsatzKasse (GEK). Data on diagnoses and treatment of insured persons aged 0-15 years were analysed for the period from 01/07/2005 to 30/06/2009 regarding the frequency of distal forearm fractures and fracture treatment. RESULTS: The overall incidence rate was 56.8 per 10 000 person-years (64.5 in boys; 48.7 in girls). Most of the distal forearm fractures occurred during spring and summer months. The majority of the fractures were immobilized in a plaster cast (84.2{\%}; n=2 609). 8.7{\%} (n=270) of the fractures were treated with closed reduction and percutaneous osteosynthesis. 4.5{\%} (n=138) were treated with closed reduction without any form of osteosynthesis. Only 1.4{\%} (n=43) of the fractures were treated with open reduction. CONCLUSION: Our study shows that boys suffer distal forearm fractures more frequently than girls and that incidences tend to be higher in older children. In addition, analyses indicated seasonal differences between the age groups. In childhood, distal forearm fractures were treated more often conservatively than operatively. However, it was remarkable that fractures in the case of closed reduction were more frequently fixed with an osteosynthesis than just by immobilization in a plaster cast.},
      author = {H{\"o}fer, J. and Hoffmann, Falk and Glaeske, G. and Sauer, K.},
      year = {2016},
      title = {[Distal Forearm Fractures in Children and Adolescents: Frequency and Health Care Provision in Germany]},
      keywords = {*Forearm Injuries/epidemiology/therapy;*Radius Fractures/epidemiology/therapy;*Ulna Fractures/epidemiology/therapy;Adolescent;Child;Child, Preschool;Female;Forearm;Germany/epidemiology;Humans;Infant;Infant, Newborn;Male},
      pages = {e1-e9},
      volume = {81},
      number = {1},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen},
      originalyear = {Distale Unterarmfrakturen im Kindes- und Jugendalter: Haufigkeit und Versorgungsgeschehen in Deutschland.},
      doi = {10.1055/s-0042-116225},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/27813043} }
  • [article] bibtex
    G. Schmiemann, J. Noll, und F. Hoffmann, "[Resistance testing for urinary tract infections. A barrier to guideline implementation]" Urologe A, vol. 55, iss. 4, pp. 514-519, 2016.
    @article{Schmiemann.2016, abstract = {BACKGROUND: Urinary tract infections (UTI) are among the most common reasons for antibiotic prescriptions. Due to increasing resistance rates, antibiotic therapy should be targeted and based on evidence-based recommendations. Test results and recommendations by medical laboratories have a relevant impact on the choice of antibiotics. The extent to which medical laboratories consider antibiotics recommended by evidence-based treatment guidelines in microbiological testing is unclear. OBJECTIVES: The aim of the present study is to assess whether guideline recommendations for antibiotic therapy of UTI are taken into account by medical laboratories in northern Germany. MATERIALS AND METHODS: A standardized and piloted questionnaire was used in our telephone survey. All microbiological laboratories in northern Germany (Hamburg, Bremen, Lower Saxony, Schleswig-Holstein, and Mecklenburg-Western Pomerania; n = 82) were asked about their standards in diagnosing and microbiological testing of urine cultures. RESULTS: A total of 71 of the 82 contacted laboratories perform microbiological tests, whereby 40 of these participated (56 {\%}). Most of the laboratories (43 {\%}) routinely perform microbiological testing when bacterial counts were {\textgreater}/= 10(4) colony forming units per ml (CFU/ml), 15 {\%} {\textgreater}/= 10(5) CFU/ml, 17 {\%} {\textgreater}/= 10(3) CFU/ml, and 8 {\%} {\textgreater}/= 10(2) CFU/ml. Antibiotic testing includes ciprofloxacin (95 {\%}), cotrimoxazole (87.5 {\%}), trimethoprim (57 {\%}), fosfomycin (85 {\%}), and nitrofurantoin (72 {\%}). CONCLUSIONS: The diagnostic threshold recommended in evidence-based guidelines (10(3) CFU/ml) is used only by a few laboratories. Antibiotics recommended as a first line therapy are only partly taken into account in microbiological testing. This variance in different diagnostic thresholds and microbiological testing is a barrier to guideline implementation.},
      author = {Schmiemann, Guido and Noll, J. and Hoffmann, Falk},
      year = {2016},
      title = {[Resistance testing for urinary tract infections. A barrier to guideline implementation]},
      keywords = {*Drug Resistance, Bacterial;*Practice Guidelines as Topic;Anti-Bacterial Agents/therapeutic use;Antibiotics;Bacterial Typing Techniques/standards/statistics {\&} numerical data;Diagnostics, microbiological;Drug resistance, bacterial;Female;Germany/epidemiology;Guideline Adherence/*statistics {\&} numerical data;Health services research;Humans;Male;Medicine, evidence-based;Microbial Sensitivity Tests/*standards/statistics {\&} numerical data;Urinary Tract Infections/diagnosis/drug therapy/*microbiology;Urology/*standards},
      pages = {514--519},
      volume = {55},
      number = {4},
      issn = {1433-0563 (Electronic) 0340-2592 (Linking)},
      journal = {Urologe A},
      originalyear = {Resistenzprufung bei Harnwegsinfektionen. Eine Barriere fur die Leitlinienimplementierung.},
      doi = {10.1007/s00120-015-3974-1},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/26450093} }
  • [article] bibtex
    G. Schmiemann, S. Herget-Rosenthal, und F. Hoffmann, "[Medical services for nursing home residents : Results of the study on inappropriate medication in patients with renal insufficiency in nursing homes]" Z Gerontol Geriatr, vol. 49, iss. 8, pp. 727-733, 2016.
    @article{Schmiemann.2016b, abstract = {BACKGROUND: In Germany approximately 800,000 people are living in nursing homes. Outpatient medical treatment is provided by general practitioners (GP) and a variety of medical specialists. While nearly all residents have regular contact with GPs, care by specialists differs between the various disciplines. AIM: In this study an assessment of medical treatment for nursing home residents by GPs and specialists was made and compared with the available diagnoses. MATERIAL AND METHODS: Between October 2014 and April 2015 a cross-sectional study was conducted in nursing homes in Bremen and the surrounding areas. Anonymized data based on residents' files were collated by nursing staff. Every contact with various specialists within the preceding 12 months was assessed and grouped into (a) no physician visit, (b) resident visited physician and (c) physician visited resident. Analyses were stratified for age, sex and level of care dependency as well as dementia and further comorbidities. RESULTS: A total of 852 residents in 21 nursing homes were included (mean age 83.5 years, 76.5 {\%} female) in the study. Dementia was diagnosed in 57.7 {\%}. Nearly all residents had had contact with their GP in the previous 12 months, mostly by home visits (96.9 {\%}). The majority (54.5 {\%}) had not seen a dentist in the preceding 12 months and 25.4 {\%} had been visited by a dentist. Of the residents 47.4 {\%} were visited by a neurologist or psychiatrist but only 4.5 {\%} visited these specialists in their practice. Higher care dependency and younger age were associated with more frequent visits by neurologists and psychiatrists. Contact rates to ophthalmologists (29.3 {\%}) and urologists (20.5 {\%}) were less frequent. A diagnosis of diabetes mellitus had no influence on the contact rate with ophthalmologists. CONCLUSION: Medical care by specialists is characterized by huge variations. Besides a frequent contact rate with GPs there seems to be an undersupply regarding care by dentists and ophthalmologists.},
      author = {Schmiemann, Guido and Herget-Rosenthal, Stefan and Hoffmann, Falk},
      year = {2016},
      title = {[Medical services for nursing home residents : Results of the study on inappropriate medication in patients with renal insufficiency in nursing homes]},
      keywords = {*Health services research;*Home visits;*Office visits;*Physicians, family;*Specialists;Age Distribution;Aged;Aged, 80 and over;Dementia/drug therapy/*epidemiology;Drug Prescriptions/statistics {\&} numerical data;Female;General Practitioners/statistics {\&} numerical data;Germany/epidemiology;Homes for the Aged/*statistics {\&} numerical data;Humans;Inappropriate Prescribing/*statistics {\&} numerical data;Male;Nursing Care/statistics {\&} numerical data;Nursing Homes/*statistics {\&} numerical data;Office Visits/statistics {\&} numerical data;Renal Agents/*therapeutic use;Renal Insufficiency/*drug therapy/epidemiology;Sex Distribution},
      pages = {727--733},
      volume = {49},
      number = {8},
      issn = {1435-1269 (Electronic) 0948-6704 (Linking)},
      journal = {Z Gerontol Geriatr},
      originalyear = {Arztliche Versorgung von Pflegeheimbewohnern : Ergebnisse der Studie {\textquotedbl}Inappropriate medication in patients with renal insufficiency in nursing homes{\textquotedbl}.},
      doi = {10.1007/s00391-015-1010-0},
      file = {http://www.ncbi.nlm.nih.gov/pubmed/26687365} }
  • N. Volkening, A. Unni, B. S. Löffler, S. Fudickar, J. W. Rieger, und A. Hein, "Characterizing the Influence of Muscle Activity in fNIRS Brain Activation Measurements" IFAC-PapersOnLine, vol. 49, iss. 11, pp. 84-88, 2016.
    @article{Volkening.2016, abstract = {Driving is a complex and cognitively demanding task. It is essential to assess the cognitive state of the driver in order to design cognitive technical systems that can adapt to different driver cognitive states. Our research attempts to assess these states using functional Near Infrared Spectroscopy (fNIRS) by measuring brain activity in a virtual reality driving simulator. However, the fNIRS brain activation measurements could be influenced by muscle activity and we wanted to investigate this phenomenon. For this, we designed a paradigm with two conditions (listen, teeth clench) which show a significant contrast in the influence of muscle activity. We observed that the muscle hemodynamic response can show a higher magnitude of signal change compared to brain hemodynamic response. The muscle hemodynamic response showed an increase in deoxygenated hemoglobin (HbR) whereas the brain hemodynamic response showed a decrease in HbR. Moreover, the dynamics of the brain and muscle hemodynamic response differed. The brain response showed the same latency for oxygenated hemoglobin (HbO) and HbR while the muscle HbR response had a slower latency compared to HbO. We concluded that the fNIRS brain activation measurements could indeed be influenced by muscle activity. We were also able to determine some characteristics of the muscle hemodynamic response.},
      author = {Volkening, Nils and Unni, Anirudh and L{\"o}ffler, Birte Sofie and Fudickar, Sebastian and Rieger, Jochem W. and Hein, Andreas},
      year = {2016},
      title = {Characterizing the Influence of Muscle Activity in fNIRS Brain Activation Measurements},
      url = {http://linkinghub.elsevier.com/retrieve/pii/S2405896316313349},
      keywords = {accepted;full paper;OFFIS=G-AIT/AHT/CSE;UNIAMT;UNICSE},
      pages = {84--88},
      volume = {49},
      number = {11},
      issn = {24058963},
      journal = {IFAC-PapersOnLine},
      doi = {10.1016/j.ifacol.2016.08.013},
      file = {Volkening et al. - 2016 - Characterizing the Influence of Muscle Activity in fNIRS Brain Activation Measurements:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Volkening et al. - 2016 - Characterizing the Influence of Muscle Activity in fNIRS Brain Activation Measurements.pdf:pdf} }
  • [incollection] bibtex
    M. Isken und A. Hein, "Continuous Geriatric Assessments Supported by a Mobile Service Robot: Movement Analysis" in Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015, Wichert, R. und Klausing, H., Eds., Springer International Publishing, 2016, pp. 37-46.
    @incollection{Isken.2016, abstract = {This document describes a method to measure geriatric assessment data by using a mobile robotic platform that is able to track and analyze human motion parameters. The information gathered by this system can be used to assess the user's health status. Geriatric mobility assessments conducted by a mobile robot provide significant advantages over current methodologies. For example, sensor data can be used to track multiple assessments at once. Additionally, the robot navigation capabilities can be enhanced by the use of geriatric assessment data. This paper concentrates on the movement analysis aspect of the whole system due to the limited space.},
      author = {Isken, Melvin and Hein, Andreas},
      title = {Continuous Geriatric Assessments Supported by a Mobile Service Robot: Movement Analysis},
      keywords = {accepted;full paper},
      pages = {37--46},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-319-26345-8},
      series = {Advanced Technologies and Societal Change},
      editor = {Wichert, Reiner and Klausing, Helmut},
      booktitle = {Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015},
      year = {2016},
      doi = {10.1007/978-3-319-26345-8{\textunderscore }4},
      file = {Isken, Hein - 2016 - Continuous Geriatric Assessments Supported by a Mobile Service Robot Movement Analysis:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Isken, Hein - 2016 - Continuous Geriatric Assessments Supported by a Mobile Service Robot Movement Analysis.pdf:pdf} }
  • [inproceedings] bibtex
    S. Hellmers, S. Fudickar, C. Büse, L. Dasenbrock, A. Heinks, J. Bauer, und A. Hein, "Technology Supported Geriatric Assessment" in Proc. Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016, Frankfurt, 2016, pp. 85-100.
    @inproceedings{Hellmers.2016, abstract = {Healthy aging is a core societal aim especially regarding the demographic change. But with aging, functional decline can occur and this is a major challenge for health care systems. For the evaluation of the health of older adults and the identification of early changes associated with functional and cognitive decline, clinical geriatric assessments are a well-established approach. Ideally, the assessments should take place at home of the older adults or even in their daily life, to get an unbiased functional status. Therefore, we introduce a technology supported geriatric assessment as an intermediate step to a home-assessment or in future to sensor-based-assessments in daily life. Beside various ambient sensors, a sensor belt is used during the assessments and for 1 week in the participants' daily life. We discuss the suitability of our measuring devices for an ambient home-assessment and evaluate the sensors in comparison to valid measurements. Thereby, we show that light barrier measurements achieve a high sensitivity and a good correlation to manual measurements through study nurses or physical therapists.},
      author = {Hellmers, Sandra and Fudickar, Sebastian and B{\"u}se, Clemens and Dasenbrock, Lena and Heinks, Andrea and Bauer, J{\"u}rgen and Hein, Andreas},
      title = {Technology Supported Geriatric Assessment},
      keywords = {accepted;full paper;UNIAMT},
      pages = {85--100},
      publisher = {{VDE Verlag}},
      isbn = {978-3-319-52322-4},
      editor = {Wichert, Reiner and Mand, Beate},
      booktitle = {Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016},
      year = {2016},
      address = {Frankfurt},
      doi = {10.1007/978-3-319-52322-4{\textunderscore }6},
      file = {Hellmers et al. - 2017 - Technology Supported Geriatric Assessment:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Hellmers et al. - 2017 - Technology Supported Geriatric Assessment.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    C. Lins, A. Hein, L. Halder, und P. Gronotte, "Still in flow --- long-term usage of an activity motivating app for seniors" in Proc. 2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom), Munich, 2016, pp. 1-4.
    @inproceedings{Lins.2016b, abstract = {In this paper, results from the long-term usage of a mobile application (app) for seniors that encourages physical and mental activity are presented. The application was designed for elderly inhabitants of senior residences to motivate them to increase their physical and mental activity in everyday life. Usage statistics of 82 users for about two years were processed and show that the active elderly users can be clustered in two groups with either increasing or decreasing and very little constant activity. Users with decreasing activity have also shown decreasing usage errors with the app's user interface which may indicate that they are growing out of the app. The results show insight view about the usage and suggest that the Concept of Flow can be applied here.},
      author = {Lins, Christian and Hein, Andreas and Halder, Luca and Gronotte, Philipp},
      title = {Still in flow --- long-term usage of an activity motivating app for seniors},
      url = {http://ieeexplore.ieee.org/document/7749476/},
      keywords = {accepted},
      pages = {1--4},
      publisher = {IEEE},
      isbn = {978-1-5090-3370-6},
      booktitle = {2016 IEEE 18th International Conference on e-Health Networking, Applications and Services (Healthcom)},
      year = {2016},
      address = {Munich},
      doi = {10.1109/HealthCom.2016.7749476},
      file = {Lins et al. - 2016 - Still in flow — long-term usage of an activity motivating app for seniors:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins et al. - 2016 - Still in flow — long-term usage of an activity motivating app for seniors.pdf:pdf} }
  • [incollection] bibtex | Dokument aufrufen Dokument aufrufen
    C. Lins, S. M. Müller, und A. Hein, "Model-Based Approach for Posture and Movement Classification in Working Environments" in Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015, Wichert, R. und Klausing, H., Eds., Springer International Publishing, 2016, pp. 25-33.
    @incollection{Lins.2016, abstract = {In this paper, we present an approach for model-based movement and posture classification in working environments. The approach presented here is designed for long-term in-situ observations of and by workers in their workplaces. The proposed model is adaptable to different input data, e.g., skeleton data from either an Inertial Measurement Unit (IMU) or a skeleton derived from an optical sensor such as Kinect. We present a preliminary design of the model and suggest algorithms suitable for real-time usage of the model in an IMU-based motion capture suite. In an experiment we measured the weight on the knee while performing different kneeing postures to show the dependence of posture angles on the knee load.},
      author = {Lins, Christian and M{\"u}ller, Sebastian Matthias and Hein, Andreas},
      title = {Model-Based Approach for Posture and Movement Classification in Working Environments},
      url = {http://www.springer.com/de/book/9783319263434 http://link.springer.com/10.1007/978-3-319-26345-8_3},
      keywords = {accepted;full paper;Working environment Model Posture Classification K},
      pages = {25--33},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-319-26345-8},
      series = {Advanced Technologies and Societal Change},
      editor = {Wichert, Reiner and Klausing, Helmut},
      booktitle = {Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015},
      year = {2016},
      doi = {10.1007/978-3-319-26345-8{\textunderscore }3},
      file = {Lins, Müller, Hein - 2016 - Model-Based Approach for Posture and Movement Classification in Working Environments:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins, Müller, Hein - 2016 - Model-Based Approach for Posture and Movement Classification in Working Environments.pdf:pdf} }
  • [incollection] bibtex | Dokument aufrufen Dokument aufrufen
    C. Lins, M. Frenken, L. Halder, und A. Hein, "Designing and Introducing an Activity Motivating Mobile Web App Platform for Seniors" in Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015, Wichert, R. und Klausing, H., Eds., Springer International Publishing, 2016, pp. 15-24.
    @incollection{Lins.2016c, abstract = {In this paper, we present results from the VERA project regarding design, usability, and motivation for long-term usage of a mobile web app platform that encourages physical and mental activity. The system is designed for elderly inhabitants of senior residences to motivate them to increase their physical and mental activity in everyday life. Activities can be logged in five different categories: everyday activities, endurance, strength, mental, and special activities. The data of a residential home and an assisted living facility and a total of 29 users were analyzed. The results show insight view about the usage and suggest that accompanying help can improve the long-term sustainability of the motivating effect.},
      author = {Lins, Christian and Frenken, Melina and Halder, Luca and Hein, Andreas},
      title = {Designing and Introducing an Activity Motivating Mobile Web App Platform for Seniors},
      url = {http://link.springer.com/10.1007/978-3-319-26345-8_2},
      keywords = {accepted;full paper;Motivation Aged people Tablet Activity Web app Sen},
      pages = {15--24},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-319-26345-8},
      series = {Advanced Technologies and Societal Change},
      editor = {Wichert, Reiner and Klausing, Helmut},
      booktitle = {Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015},
      year = {2016},
      doi = {10.1007/978-3-319-26345-8{\textunderscore }2},
      file = {Lins et al. - 2016 - Designing and Introducing an Activity Motivating Mobile Web App Platform for Seniors:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Lins et al. - 2016 - Designing and Introducing an Activity Motivating Mobile Web App Platform for Seniors.pdf:pdf} }
  • [incollection] bibtex | Dokument aufrufen Dokument aufrufen
    S. M. Müller, E. Steen, und A. Hein, "Part II: Inferring Multi-person Presence in Home Sensor Networks" in Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015, Wichert, R. und Klausing, H., Eds., Springer International Publishing, 2016, pp. 47-56.
    @incollection{Muller.2016, abstract = {We present an evaluation of two approaches to the problem of inferring the presence of multiple persons in networks of binary sensors. This problem is critical for many applications of Ambient Assisted Living that benefit from knowledge of single- and multi-person presence where data is collected using ambient sensors. Both approaches make use of a graph representing sensors and their spatial relations. One approach uses a simple statistical method to derive a minimum number of people present, the other precisely tracks people through the sensor network. Both approaches are evaluated in a low and higher resolution setting on data of two persons inhabiting a laboratory equipped with motion sensors and contact sensors. Although the latter approach performs well tracking multiple persons, its inability to distinguish inactivity and absence make the former approach more suitable for this task, independent of resolution.},
      author = {M{\"u}ller, Sebastian Matthias and Steen, Enno-Edzard and Hein, Andreas},
      title = {Part II: Inferring Multi-person Presence in Home Sensor Networks},
      url = {http://link.springer.com/10.1007/978-3-319-26345-8_5},
      keywords = {Multi-target tracking Ambient Assisted Living},
      pages = {47--56},
      publisher = {{Springer International Publishing}},
      isbn = {978-3-319-26345-8},
      series = {Advanced Technologies and Societal Change},
      editor = {Wichert, Reiner and Klausing, Helmut},
      booktitle = {Ambient Assisted Living: 8. AAL-Kongress 2015,Frankfurt/M, April 29-30. April, 2015},
      year = {2016},
      doi = {10.1007/978-3-319-26345-8{\textunderscore }5},
      file = {Müller, Steen, Hein - 2016 - Inferring Multi-person Presence in Home Sensor Networks:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Müller, Steen, Hein - 2016 - Inferring Multi-person Presence in Home Sensor Networks.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    S. Fudickar, M. Isken, J. Fleßner, N. Volkening, E. Steen, und A. Hein, "Gesture controlled hospital beds for home care" in Proc. Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016, Frankfurt, 2016, pp. 103-118.
    @inproceedings{Fudickar.2016, abstract = {This article introduces a gesture-based user interface for hospi-tal beds that enables caregivers to focus on their patients and interact with them with both hands during mobilizing or transferring them. Gestures are detected either via static (96{\%} sensitivity) or dynamic gestures (67.5 {\%} sen-sitivity) and might be corrected by an extra repetition. Once gestures are correctly detected, caregivers can trigger bed movements via a foot switch as a hands-free operation, which as well functions as a dead man button. The evaluation of the usability through interviews with caregivers highlighted the system's general applicability, but as well some future challenges that have to be solved in order to achieve a system for every-day use.},
      author = {Fudickar, Sebastian and Isken, Melvin and Fle{\ss}ner, Jannik and Volkening, Nils and Steen, Enno-Edzard and Hein, Andreas},
      title = {Gesture controlled hospital beds for home care},
      url = {http://link.springer.com/chapter/10.1007/978-3-319-52322-4_7/fulltext.html},
      keywords = {accepted;full paper;UNIAMT},
      pages = {103--118},
      publisher = {{VDE Verlag}},
      isbn = {978-3-319-52322-4},
      editor = {Wichert, Reiner and Mand, Beate},
      booktitle = {Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016},
      year = {2016},
      address = {Frankfurt},
      doi = {10.1007/978-3-319-52322-4},
      file = {Fudickar et al. - 2017 - Gesture controlled hospital beds for home care:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Fudickar et al. - 2017 - Gesture controlled hospital beds for home care.pdf:pdf} }
  • [inproceedings] bibtex | Dokument aufrufen Dokument aufrufen
    A. Gerka, M. Eichelberg, N. Abmeier, M. Schwarz, S. Brinkmann-Gerdes, und A. Hein, "QuoVadis -- Definition of Requirements and Conception for Interconnected Living in a Quarter for Dementia Patients" in Proc. Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016, Frankfurt, 2016, pp. 27-39.
    @inproceedings{Gerka.2016b, abstract = {The determination of a suitable living and care arrangement for dementia patients is a difficult decision for the patients themselves and their relatives. This decision becomes even more difficult if only classical arrangements are considered. Such arrangements, like care in long term care facilities or care in the own apartment applied by the relatives, often do not address the needs of dementia patients appropriately or cause significant stress for the relatives. Therefore, a new liv-ing arrangement concept is developed in the research project QuoVadis, which is called ``interconnected living in the quarter''. In this new living arrangement dementia patients can stay in their own accommodation while they are integrat-ed into a care concept at the same time. In a quarter, a ``quarter manager'' is responsible for organizing care and help for the dementia patients. To empower the quarter manager to support the residents, an intelligent sensor-based system is developed. This system will be integrated into the apartments of the dementia patients. This article presents the require-ments definition for the technical system. Furthermore, a concept to fulfil these requirements is presented. In this con-cept, an adaptive decision support system (ADSS) will be presented.},
      author = {Gerka, Alexander and Eichelberg, Marco and Abmeier, Nadine and Schwarz, Marie-Luise and Brinkmann-Gerdes, Stefanie and Hein, Andreas},
      title = {QuoVadis -- Definition of Requirements and Conception for Interconnected Living in a Quarter for Dementia Patients},
      url = {https://www.vde-verlag.de/proceedings-en/454212078.html},
      keywords = {Informationenfehlen},
      pages = {27--39},
      publisher = {{VDE Verlag}},
      isbn = {978-3-319-52322-4},
      editor = {Wichert, Reiner and Mand, Beate},
      booktitle = {Ambient Assisted Living. 9. AAL-Kongress, Frankfurt/M, Germany, April 20--21, 2016},
      year = {2016},
      address = {Frankfurt},
      doi = {10.1007/978-3-319-52322-4},
      file = {Gerka et al. - 2017 - QuoVadis – Definition of Requirements and Conception for Interconnected Living in a Quarter for Dementia Patients:C\:\\Users\\zist2149\\AppData\\Local\\Mendeley Ltd\\Mendeley Desktop\\Downloaded\\Gerka et al. - 2017 - QuoVadis – Definition of Requirements and Conception for Interconnected Living in a Quarter for Dementia Patients.pdf:pdf} }
  • [article] bibtex
    Daniel Künkel, Birgit Bomsdorf, Rainer Röhrig, Janko Ahlbrandt, und Markus A. Weigand, "Participative development of touchless user interfaces : elicitation and evaluation of contactless hand gestures for anesthesia" Proceedings of the International Conferences on Interfaces and Human Computer Interaction 2015, Game and Entertainment Technologies 2015 and Computer Graphics, Visualization, Computer Vision and Image Processing 2015 : Las Palmas de Gran Canaria, Spain, July 22-24, 2015 [Lissabon?] : IADIS Press (2015), p. 43-50 <43-50, 2015.
    @article{DanielKunkel.2015,
      author = {{Daniel K{\"u}nkel} and {Birgit Bomsdorf} and {Rainer R{\"o}hrig} and {Janko Ahlbrandt} and {Markus A. Weigand}},
      year = {2015},
      title = {Participative development of touchless user interfaces : elicitation and evaluation of contactless hand gestures for anesthesia},
      journal = {Proceedings of the International Conferences on Interfaces and Human Computer Interaction 2015, Game and Entertainment Technologies 2015 and Computer Graphics, Visualization, Computer Vision and Image Processing 2015 : Las Palmas de Gran Canaria, Spain, July 22-24, 2015 [Lissabon?] : IADIS Press (2015), p. 43-50 {\textless}43-50} }
  • [article] bibtex
    Rainer Röhrig, Myriam Lipprandt, Janko Ahlbrandt, Markus A. Weigand, und Christopher Neuhaus, "Nutzen und Risiken der IT in der Medizin" E-health-compass / Intensiv- und Notfallmedizin Offenbach : Health-Care-Com Vol. 4 (2015), p. 4-7 4<4-7, 2015.
    @article{RainerRohrig.2015,
      author = {{Rainer R{\"o}hrig} and {Myriam Lipprandt} and {Janko Ahlbrandt} and {Markus A. Weigand} and {Christopher Neuhaus}},
      year = {2015},
      title = {Nutzen und Risiken der IT in der Medizin},
      journal = {E-health-compass / Intensiv- und Notfallmedizin Offenbach : Health-Care-Com Vol. 4 (2015), p. 4-7 4{\textless}4-7} }
  • [article] bibtex
    Rainer Röhrig und Axel Junger, "Vor- und Nachteile verschiedener IT-Lösungsarchitekturen" Handbuch OP-Management : Strategien, Konzepte, Methoden Berlin : Med. Wiss. Verl.-Ges. (2015), p. 745-750 <745-750, 2015.
    @article{RainerRohrig.2015b,
      author = {{Rainer R{\"o}hrig} and {Axel Junger}},
      year = {2015},
      title = {Vor- und Nachteile verschiedener IT-L{\"o}sungsarchitekturen},
      journal = {Handbuch OP-Management : Strategien, Konzepte, Methoden Berlin : Med. Wiss. Verl.-Ges. (2015), p. 745-750 {\textless}745-750} }
  • [article] bibtex
    Rainer Röhrig und Axel Junger, "Einsatzmöglichkeiten von IT im OP-Management" Handbuch OP-Management : Strategien, Konzepte, Methoden Berlin : Med. Wiss. Verl.-Ges. (2015), p. 741-744 <741-744, 2015.
    @article{RainerRohrig.2015c,
      author = {{Rainer R{\"o}hrig} and {Axel Junger}},
      year = {2015},
      title = {Einsatzm{\"o}glichkeiten von IT im OP-Management},
      journal = {Handbuch OP-Management : Strategien, Konzepte, Methoden Berlin : Med. Wiss. Verl.-Ges. (2015), p. 741-744 {\textless}741-744} }
  • [article] bibtex
    Rainer Röhrig und Axel Junger, "Allgemeine Einführung in die EDV" Handbuch OP-Management : Strategien, Konzepte, Methoden Berlin : Med. Wiss. Verl.-Ges. (2015), p. 735-740 <735-740, 2015.
    @article{RainerRohrig.2015d,
      author = {{Rainer R{\"o}hrig} and {Axel Junger}},
      year = {2015},
      title = {Allgemeine Einf{\"u}hrung in die EDV},
      journal = {Handbuch OP-Management : Strategien, Konzepte, Methoden Berlin : Med. Wiss. Verl.-Ges. (2015), p. 735-740 {\textless}735-740} }
  • [article] bibtex
    Sebastian Claudius Semler und Rainer Röhrig, "LOINC - internationale Nomenklatur zur Kodierung von medizinischen Untersuchungen und Befunden" Terminologien und Ordnungssysteme in der Medizin : Standortbestimmung und Handlungsbedarf in den deutschsprachigen Ländern Berlin : MWV, Medizinisch Wissenschaftliche Verlagsgesellschaft (2015), p. 97-134 <97-134, 2015.
    @article{SebastianClaudiusSemler.2015,
      author = {{Sebastian Claudius Semler} and {Rainer R{\"o}hrig}},
      year = {2015},
      title = {LOINC - internationale Nomenklatur zur Kodierung von medizinischen Untersuchungen und Befunden},
      journal = {Terminologien und Ordnungssysteme in der Medizin : Standortbestimmung und Handlungsbedarf in den deutschsprachigen L{\"a}ndern Berlin : MWV, Medizinisch Wissenschaftliche Verlagsgesellschaft (2015), p. 97-134 {\textless}97-134} }
  • [book] bibtex
    Versorgungsforschung. Zwischen Routinedaten, Qualitätssicherung und Patientenorientierung, Trittin, C., Ed., Siegburg: Asgard, 2015.
    @book{Trittin.2015, year = {2015},
      title = {Versorgungsforschung. Zwischen Routinedaten, Qualit{\"a}tssicherung und Patientenorientierung},
      address = {Siegburg},
      publisher = {Asgard},
      editor = {Trittin, Cornelia} }
  • [article] bibtex
    Andreas Hecker, Emmanuel René Karl Schneck, Rainer Röhrig, Fritz Christian Roller, B. Hecker, J. Holler, Christian Koch, M. Hecker, M. Reichert, Christoph Lichtenstern, Gabriele Anja Krombach, W. Padberg, und Markus A. Weigand, "The impact of early surgical intervention in free intestinal perforation : a time-to-intervention pilot study" World journal of emergency surgery : WJES London : BioMed Central Bd. 10 (2015), 54, insges. 10 S. 10:54, p. online-ressource, 2015.
    @article{AndreasHecker.2015,
      author = {{Andreas Hecker} and {Emmanuel Ren{\'e} Karl Schneck} and {Rainer R{\"o}hrig} and {Fritz Christian Roller} and {B. Hecker} and {J. Holler} and {Christian Koch} and {M. Hecker} and {M. Reichert} and {Christoph Lichtenstern} and {Gabriele Anja Krombach} and {W. Padberg} and {Markus A. Weigand}},
      year = {2015},
      title = {The impact of early surgical intervention in free intestinal perforation : a time-to-intervention pilot study},
      pages = {Online-Ressource},
      journal = {World journal of emergency surgery : WJES London : BioMed Central Bd. 10 (2015), 54, insges. 10 S. 10:54},
      doi = {10.1186/s13017-015-0047-0} }
  • [article] bibtex
    C. Bachmann und F. Hoffmann, "Autismus-Spektrum-Störungen in Deutschland: Diagnoseprävalenz, medizinische Versorgung und zeitliche Trends" Versorgungs-Report, vol. 2016, pp. 167-184, 2015.
    @article{Bachmann.2015b,
      author = {Bachmann, C. and Hoffmann, Falk},
      year = {2015},
      title = {Autismus-Spektrum-St{\"o}rungen in Deutschland: Diagnosepr{\"a}valenz, medizinische Versorgung und zeitliche Trends},
      pages = {167--184},
      volume = {2016},
      journal = {Versorgungs-Report} }
  • [article] bibtex
    Christian Koch, Rainer Röhrig, Tobias Monz, Andreas Hecker, Florian Uhle, Emmanuel René Karl Schneck, Markus A. Weigand, und Christoph Lichtenstern, "Prospective evaluation of regional oxygen saturation to estimate central venous saturation in sepsis" Journal of clinical monitoring and computing : the international journal for technology in anesthesia practice : formerly Journal of clinical monitoring, and International Journal of Clinical Monitoring and computing Dordrecht [u.a.] : Springer Science + Business Media B.V Vol. 29, No. 4 (2015), p. 443-453 29:4<443-453, p. online-ressource, 2015.
    @article{ChristianKoch.2015,
      author = {{Christian Koch} and {Rainer R{\"o}hrig} and {Tobias Monz} and {Andreas Hecker} and {Florian Uhle} and {Emmanuel Ren{\'e} Karl Schneck} and {Markus A. Weigand} and {Christoph Lichtenstern}},
      year = {2015},
      title = {Prospective evaluation of regional oxygen saturation to estimate central venous saturation in sepsis},
      pages = {Online-Ressource},
      journal = {Journal of clinical monitoring and computing : the international journal for technology in anesthesia practice : formerly Journal of clinical monitoring, and International Journal of Clinical Monitoring and computing Dordrecht [u.a.] : Springer Science + Business Media B.V Vol. 29, No. 4 (2015), p. 443-453 29:4{\textless}443-453},
      doi = {10.1007/s10877-015-9683-x{\$}{\$}Elinktorsrc} }
  • [article] bibtex
    Marius Merz, Rainer Röhrig, Markus A. Weigand, und Valesco Wladimir Mann, "Larynx-Maske (am Beispiel der LMA Supreme\texttrademark)" Notfallmedizin up2date Stuttgart : Thieme Vol. 10, No. 4 (2015), p. 301-307 10:4<301-307, p. online-ressource, 2015.
    @article{MariusMerz.2015,
      author = {{Marius Merz} and {Rainer R{\"o}hrig} and {Markus A. Weigand} and {Valesco Wladimir Mann}},
      year = {2015},
      title = {Larynx-Maske (am Beispiel der LMA Supreme{\texttrademark})},
      pages = {Online-Ressource},
      journal = {Notfallmedizin up2date Stuttgart : Thieme Vol. 10, No. 4 (2015), p. 301-307 10:4{\textless}301-307},
      doi = {10.1055/s-0041-110894} }
  • [article] bibtex
    A. Timmer, B. Schütte, und J. Peplies, "Versorgungsgerechtigkeit bei Kindern mit CED. Zwischeninformation zur Ripi-Befragungsstudie" Bauchredner, iss. 1, pp. 63-66, 2015.
    @article{Timmer.2015b,
      author = {Timmer, Antje and Sch{\"u}tte, B. and Peplies, Jenny},
      year = {2015},
      title = {Versorgungsgerechtigkeit bei Kindern mit CED. Zwischeninformation zur Ripi-Befragungsstudie},
      pages = {63--66},
      number = {1},
      journal = {Bauchredner} }
  • [article] bibtex
    Valesco Wladimir Mann, S. T. Mann, N. Lenz, Rainer Röhrig, und M. Henrich, "Larynxmaske oder Larynxtubus : welches Hilfsmittel zur extraglottischen Atemwegssicherung ist das richtige für den Rettungsdienst?" Notfall & Rettungsmedizin : Organ von: Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin Berlin : Springer Vol. 18, No. 5 (2015), p. 370-376 18:5<370-376, p. online-ressource, 2015.
    @article{ValescoWladimirMann.2015,
      author = {{Valesco Wladimir Mann} and {S. T. Mann} and {N. Lenz} and {Rainer R{\"o}hrig} and {M. Henrich}},
      year = {2015},
      title = {Larynxmaske oder Larynxtubus : welches Hilfsmittel zur extraglottischen Atemwegssicherung ist das richtige f{\"u}r den Rettungsdienst?},
      pages = {Online-Ressource},
      journal = {Notfall {\&} Rettungsmedizin : Organ von: Deutsche Interdisziplin{\"a}re Vereinigung f{\"u}r Intensiv- und Notfallmedizin Berlin : Springer Vol. 18, No. 5 (2015), p. 370-376 18:5{\textless}370-376},
      doi = {10.1007/s10049-015-0015-y{\$}{\$}Elinktorsrc} }
  • R. Khanna, J. C. Preiss, J. K. MacDonald, und A. Timmer, "Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease" Cochrane Database Syst Rev, iss. 5, 2015.
    @article{Khanna.2015,
      author = {Khanna, Reena and Preiss, Jan C. and MacDonald, John K. and Timmer, Antje},
      year = {2015},
      title = {Anti-IL-12/23p40 antibodies for induction of remission in Crohn's disease},
      url = {://WOS:000355993600022},
      number = {5},
      journal = {Cochrane Database Syst Rev},
      doi = {10.1002/14651858.CD007572.pub2} }
  • [article] bibtex
    F. Hoffmann und C. Ohlmeier, "Routinedaten im Gesundheitswesen Handbuch Sekundärdatenanalyse: Grundlagen, Methoden und Perspektiven. Rezension." Das Gesundheitswesen, vol. 77, iss. 3, p. 130, 2015.
    @article{Hoffmann.2015b,
      author = {Hoffmann, Falk and Ohlmeier, C.},
      year = {2015},
      title = {Routinedaten im Gesundheitswesen Handbuch Sekund{\"a}rdatenanalyse: Grundlagen, Methoden und Perspektiven. Rezension.},
      pages = {130},
      volume = {77},
      number = {3},
      issn = {0941-3790},
      journal = {Das Gesundheitswesen} }
  • [incollection] bibtex
    F. Hoffmann, "Versorgungsforschung mit Arzneimitteldaten der Kassen heute und morgen" in Versorgungsforschung. Zwischen Routinedaten, Qualitätssicherung und Patientenorientierung, Trittin, C., Ed., Siegburg: Asgard, 2015, pp. 99-108.
    @incollection{Hoffmann.2015g,
      author = {Hoffmann, Falk},
      title = {Versorgungsforschung mit Arzneimitteldaten der Kassen heute und morgen},
      pages = {99--108},
      publisher = {Asgard},
      editor = {Trittin, Cornelia},
      booktitle = {Versorgungsforschung. Zwischen Routinedaten, Qualit{\"a}tssicherung und Patientenorientierung},
      year = {2015},
      address = {Siegburg} }
  • [inproceedings] bibtex
    T. Krahn, F. Müller, M. Eichelberg, A. Hein, und H. Appelrath, "Sekundärnutzung klinischer Patientenakten -- Semi-automatische Detektion von Medikamentennebenwirkungen" in Proc. e-Health 2014 - Informations- und Kommunikationstechnologien im Gesundheitswesen, 2015, pp. 169-175.
    @inproceedings{Krahn.2015,
      author = {Krahn, Tobias and M{\"u}ller, Frerk and Eich