Wide-field amacrine cells

Wide-field amacrine cells

The retina houses a multitude of amacrine cell types, which display the highest diversity in morphology, transmitter repertory and putative function of all retinal neurons. So far, only few of these cell types have been thoroughly investigated, because in many cases a low population density impedes the systematic study. This is notably true for wide-field amacrine cells, which are characterized by their far-reaching cellular processes and are thought to mediate long-range lateral inhibition at the retinal output stage. By using retinas expressing fluorescent markers in only a subset of neurons we target the identification of specific wide-field amacrine cell types for studying their morphology, circuitry and physiology.  

related publications

Knop GC, Pottek M, Monyer H, Weiler R, Dedek K. 2014. Morphological and physiological properties of enhanced green fluorescent protein (EGFP)-expressing wide-field amacrine cells in the ChAT-EGFP mouse line. Eur J Neurosci. 39, 800-810. PubMed Pottek M, Knop GC, Weiler R, Dedek K. 2011. Electrophysiological characterization of GFP-expressing cell populations in the intact retina. J Vis Exp. 57, e3457. PubMed Knop GC, Feigenspan A, Weiler R, Dedek K. 2011. Inputs underlying the ON-OFF light responses of type 2 wide-field amacrine cells in TH::GFP mice. J Neurosci. 31, 4780-4791. PubMed Dedek K, Breuninger T, Pérez de Sevilla Müller L, Maxeiner S, Janssen-Bienhold U, Willecke K, Euler T, Weiler R. 2009. A novel type of interplexiform cell in the mouse retina. Eur J Neurosci. 30, 217-228. PubMed Pérez De Sevilla Müller L, Shelley J, Weiler R. 2007. Displaced amacrine cells of the mouse retina. J Comp Neurol. 505, 177-189. PubMed

(Changed: 19 Jan 2024)  | 
Zum Seitananfang scrollen Scroll to the top of the page