Prof. Dr. Jutta Kretzberg 
Tel.: +49-(0)441-798-3314 
Office: W4-0-078

Contact for pdf files:

Jutta Kretzberg

Tel.: +49-(0)441-798-3314


Journal Articles


Meiser, S., Sleeboom, J.M., Arkhypchuk, I., Sandbote, K., Kretzberg, J. (2023) Cell anatomy and network input explain differences within but not between leech touch cells at two different locations. Front. Cell. Neurosci. 17:1186997.
doi: 10.3389/fncel.2023.1186997


Scherer JS, Riedesel OE, Arkhypchuk I, Meiser S and Kretzberg J (2022) Initial Variability and Time-Dependent Changes of Neuronal Response Features Are Cell-Type-Specific. Front. Cell. Neurosci. 16:858221. doi: 10.3389/fncel.2022.858221


Kessler D, Carr CE, Kretzberg J, Ashida G (2021) Theoretical relationship between two measures of spike synchrony: Correlation index and vector strength. Front Neurosci Neurosci 15:761826. doi:10.3389/fnins.2021.761826

Ashida G, Tollin DJ, Kretzberg J (2021) Robustness of neuronal tuning to binaural sound localization cues against age-related loss of inhibitory synaptic inputs. PLoS Comput Biol 17: e1009130. doi:10.1371/journal.pcbi.1009130


Klug, J., Schmors, L., Ashida, G., & Dietz, M. (2020). Neural Rate Difference Model Can Account for Lateralization of High-frequency Stimuli. The journal of the Acoustical Society of America, 148(2), pp. 678-691

Heeringa, A., Zhang, L., Ashida, G., Beutelmann, R., Steenken, F., & Köppl, C. (2020). Temporal Coding of Single Auditory Nerve Fibers Is Not Degraded in Aging Gerbils. The Journal of Neuroscience, 40(2), pp. 343-354. doi: 10.1523/JNEUROSCI.2784-18.2019

Aralla, R., Ashida, G., Koppl, C. (2020). Binaural responses in the auditory midbrain of chicken (Gallus gallus). European Journal of Neuroscience, 51(5), pp. 1290-1304. doi: 10.1111/ejn.13891



Meiser, S., Ashida, G., & Kretzberg, J. (2019). Non-synaptic Plasticity in Leech Touch Cells. Frontiers in Physiology, 10, article 1444, pp. 1-14. doi: 10.3389/fphys.2019.01444

Ashida, G., Heinermann, H., & Kretzberg, J. (2019). Neuronal Population Model of Globular Bushy Cells Covering Unit-to-unit Variability. Public Library of Science, PLoS Computational Biology, 15 (12) article e1007563, pp. 1-38. doi: 10.1371/journal.pcbi.1007563

Köpcke, Hildebrandt, Kretzberg, Hildebrandt, K. Jannis, & Kretzberg, Jutta. (2019). Online Detection of Multiple Stimulus Changes Based on Single Neuron Interspike Intervals. Frontiers in Computational Neuroscience, 13, article 69, pp. 1-19. doi: 10.3389/fncom.2019.00069


Ashida, G. & Nogueira, W. (2018). Spike-Conducting Integrate-and-Fire Model. eNeuro, 5 (4), article UNSP e0112-18.2018. doi: 10.1523/ENEUR0.0112-18.2018

Pirschel, F., Hilgen, G., & Kretzberg, J. (2018). Effects of touch location and intensity on interneurons of the leech local bend network. Scientific reports, 8, article 3046. doi: 10.1038/s41598-018-21272-6

Fathiazar, E., Hilgen, G., & Kretzberg, J. (2018). Higher Network Activity Induced by Tactile Compared to Electrical Stimulation of Leech Mechanoreceptors. Frontiers in physiology, 9, article 173. doi: 10.3389/fphys.2018.00173

Kuokkanen PT, Ashida G, Kraemer A, McColgan T, Funabiki K, Wagner H, Köppl C, Carr CE, Kempter R  (2018) Contribution of action potentials to the extracellular field potential in the nucleus laminaris of barn owl. Journal of Neurophysiology, 119(4), pp. 1422-1436. doi: 10.1152/jn.00175.2017                      


Ashida, G., Tollin, D. J., & Kretzberg, J. (2017). Physiological models of the lateral superior olive. PLoS computational biology, 13(12), e1005903.


F. Pirschel, J. Kretzberg (2016) "Multiplexed Population Coding of Stimulus Properties by Leech Mechanosensory Cells" The Journal of Neuroscience, 36(13): 3636-3647 [Publisher Site]

Kretzberg, J, et al.  (2016), "Encoding of Tactile Stimuli by Mechanoreceptors and Interneurons of the Medicinal Leech", Frontiers in physiology 7 (2016) [Publisher Site]

Koepcke, L., Ashida, G., & Kretzberg, J. (2016). Single and Multiple Change Point Detection in Spike Trains: Comparison of Different CUSUM Methods. Frontiers in systems neuroscience10. [Publisher Site]

Saremi, Amin, et al. "A comparative study of seven human cochlear filter models." The Journal of the Acoustical Society of America140.3 (2016): 1618-1634.

Ashida, Go, Jutta Kretzberg, and Daniel J. Tollin. "Roles for coincidence detection in coding amplitude-modulated sounds." PLoS computational biology 12.6 (2016): e1004997.

Oline SN, Ashida G, Burger RM (2016) Tonotopic optimization for temporal processing in the cochlear nucleus. Journal of Neuroscience 36: 8500-8515.


Ashida, Go, Kazuo Funabiki, and Jutta Kretzberg. "Minimal conductance-based model of auditory coincidence detector neurons." PloS one 10.4 (2015): e0122796.

Carr CE, Shah S, McColgan T, Ashida G, Kuokkanen PT, Brill S, Kempter R, Wagner H (2015) Maps of interaural delay in the owl's nucleus laminaris. Journal of Neurophysiology 114: 1862-1873.

Ashida G (2015) Barn owl and sound localization. Acoustical Science and Technology 36: 275-285

Journal Articles before 2015


Hillmann, J., Kneib, T., Koepcke, L., Paz, J., León, M., & Kretzberg, J. (2014). Bivariate cumulative probit model for the comparison of neuronal encoding hypotheses. Biometrical Journal56(1), 23-43.


Kretschmer, F., Kretschmer, V., Kunze, V. P., & Kretzberg, J. (2013). OMR-arena: automated measurement and stimulation system to determine mouse visual thresholds based on optomotor responses. PloS one8(11), e78058.

Pirschel, F., & Kretzberg, J. (2013). Coding of touch properties by three types of mechanosensory cells of the leech hirudo medicinalis. BMC Neuroscience14(1), P224.

Koepcke, L., & Kretzberg, J. (2013). Change point detection for neuronal data with CUSUM and classification methods. BMC Neuroscience14(1), P223.

Ashida, Go, Kazuo Funabiki, and Catherine E. Carr. "Theoretical foundations of the sound analog membrane potential that underlies coincidence detection in the barn owl." Frontiers in computational neuroscience 7 (2013).


Pirschel, F., & Kretzberg, J. (2012). Encoding of touch location and intensity by neurons of the medicinal leech Hirudo medicinalis. BMC neuroscience13(1), P103.

Kretschmer, F., & Kretzberg, J. (2012). Automated quantification of optokinetic responses based on head-movement. BMC neuroscience13(1), P104.


Kappel, M., Pirschel, F., & Kretzberg, J. (2011). Stimulus reconstruction based on postsynaptic potentials of leech interneurons. BMC Neuroscience12(1), P179.

Köpcke, L. S., Furche, J., Paz, L. M. J., Kneib, T., & Kretzberg, J. (2011). Comparison of a Bayesian and a regression model for stimulus classification. BMC Neuroscience12(1), P178.


Kretzberg, J., Coors, T., & Furche, J. (2009). Comparison of valley seeking and T-distributed EM algorithm for spike sorting. BMC Neuroscience10(1), P47.

Kretzberg, J. Analysis of neuronal data: Bayesian stimulus reconstruction. Modern Computational Science9.

Paz, L. M. J., & Kretzberg, J. (2009). The activity of retinal ganglion cell ensembles in the turtle retina encode velocity of moving objects. BMC Neuroscience10(1), P127.


A. Thiel, M. Greschner, C.W. Eurich, J. Ammermüller, J. Kretzberg (2007)
Contribution of individual retinal ganglion cell responses to velocity and acceleration encoding.
Journal of Neurophysiology, 98: 2285-2296


J. Kretzberg, F. Kretschmer, A. Marin-Burgin (2006)
Effects of multiple spike-initiation zones in touch sensory cells of the leech.
Neurocomputing, 70: 1645-1651

A. Thiel, M. Greschner, J. Ammermüller (2006)
The temporal structure of transient ON/OFF ganglion cell responses and its relation to intra-retinal processing.
Journal of Computational Neuroscience, 21: 231-251

M. Greschner, A. Thiel, J. Kretzberg J. Ammermüller (2006)
Complex spike event pattern of transient ON/OFF retinal ganglion cells.
Journal of Neurophysiology, 96: 2845-2856.


J. Grewe, J. Kretzberg, A.-K. Warzecha, M. Egelhaaf (2003)
Impact of photon noise on the reliability of a motion-sensitive neuron in the fly´s visual system.
Journal of Neuroscience, 23(24):10776-0783
[Abstract] [Publisher Site]

J. Kretzberg, A-K. Warzecha, T. Sejnowski, M. Egelhaaf (2003)
Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs.
Neurocomputing 52-54:313-320
[Abstract] [Publisher Site]

J. Kretzberg (2003)
Informatik in den Neurowissenschaften.
FIFF Kommunikation 1/2003, Themenheft "Bioinformatik":30-36
[Abstract] [ Download pdf]

M. Egelhaaf, N. Böddeker, R. Kern, J. Kretzberg, J.P. Lindemann, A.-K. Warzecha (2003)
Visually guided orientation in flies: Case studies in computational neuroethology.
Journal of Comparative Physiology A, 189(6):401-409
[Abstract] [Publisher Site]


M. Egelhaaf, R. Kern, H. Krapp, J. Kretzberg, R. Kurtz, A.-K. Warzecha (2002)
Neural encoding of behaviourally relevant visual-motion information in the fly.
Trends in Neuroscience, 25(2):96-102
[Abstract] [Publisher Site]


J. Kretzberg, A.-K. Warzecha, M. Egelhaaf (2001)
Neural coding with graded membrane potential changes and spikes.
Journal of Computational Neuroscience, 11:153-164
[Abstract] [Publisher Site]

J. Kretzberg, M. Egelhaaf, A.-K. Warzecha (2001)
Membrane potential fluctuations determine the precision of spike timing and synchronous activity: A model study.
Journal of Computational Neuroscience, 10:79-97
[Abstract] [Publisher Site]

A.-K. Warzecha, J. Kretzberg, M. Egelhaaf (2000)
Reliability of a fly motion sensitive neuron depends on stimulus parameters. Journal of Neuroscience, 20(23):8886-8896 

[Abstract] [Publisher Site]

A.-K. Warzecha, J. Kretzberg, M. Egelhaaf (1998)
Temporal precision of the encoding of motion information by visual interneurons.
Current Biology, 8(7):359-368

Selected Recent Conference Posters

Meiser S., Ashida G., Kretzberg J. (2018)

Repeated Mechanoreceptor Stimulation Causes Two Different Forms of Activity-Dependent Neuronal Plasticity in One Cell

13th Bernstein Conference, 25th of September- 28th of September at Technische Universität in Berlin, Germany


Meiser S., Trende A., Ashida G., Kretzberg J. (2018)

Repeated mechanoreceptor stimulation causes a hyperpolarized resting potential and an increase in spike rate

11th Forum of Neuroscience, 7th of July - 11th of July in Berlin, Germany


Trende A., Ahmed Z., Meiser S., Kretzberg J. (2017)

Which Abstraction Level to choose for the Leech Local Bend Network Model?

12th Bernstein Conference, 12th of September- 15th of September at the Georg-August-Universität in Göttingen, Germany


Meiser S., Kretzberg J. (2017)

The Role of the Leech Anterior-Pagoda Cell in Tactile Information Processing

12th Göttingen Meeting of the German Neuroscience Society, 22th of March - 25th of March at the Georg-August-Universität in Göttingen, Germany


Meiser S., Trende A., Hilgen G., Kretzberg J. (2016)

Voltage-sensitive dye recording based network analysis in medicinal leech ganglia 

Neurizons2016 - ‘Speak your mind’, 31st of May – 3rd of June 2016 at the Max Planck Institute for Biophysical chemistry in Göttingen, Germany


Meiser S., Trende A., Hilgen G., Kretzberg J. (2016)

Sensory Processing in the medicinal leech

forschen@Studium, 8th of June – 9th of June 2016 at the Carl-von-Ossietzky University Oldenburg, Germany


Pirschel, F., Kuehn, O., & Kretzberg, J. (2015).

The role of mechanosensory T cells for stimulus encoding in the local bend network of the leech. 

BMC Neuroscience16(1), P132.

Book chapters

Dietz M, Ashida G (2021) Computational Models of binaural processing. In: R. Litvsky, M Gouppell, R.R.Fay, A.N. Popper (eds), Binaural Hearing, Springer Handbook of Auditory Research Vol 73, Chapter 10, pp 281-315. Springer. doi:10.1007/978-3-030-57100-9_10

Nogueira W, Ashida G (2018) Development of a model of the electrically stimulated auditory nerve. In: Biomedical Technology, Lecture Notes in Applied and Computational Mechanics P. Wriggers and T. Lenartz (eds.). pp 349-362. Springer International

Carr CE, Ashida G, Wagner H, McColgan T, Kempter R (2016) The role of conduction delay in creating sensitivity to interaural time differences. Advances in Experimental Medicine and Biology 894: 189-196.

Kretzberg J, Ernst UA (2013). The Visual System. in: Neurosciences - From Molecule to Behavior: A University Textbook. Springer Verlag, pp. 363-407.

J. Kretzberg (2009) Analysis of Neuronal Data: Bayesian Stimulus Reconstruction. In R. Leidl and A.K. Hartmann (eds.) Modern Computational Science 09. BIS-Verlag, Oldenburg

(Changed: 19 Jan 2024)  | 
Zum Seitananfang scrollen Scroll to the top of the page