Contact

Prof. Dr. Karl-Wilhelm Koch
Tel.: +49-(0)441-798-3640
Office: W4 1-137
E-mail: karl.w.koch@uol.de


2021 - 2022

2021

Cudia, D., Roseman, G.P., Assafa, T.E., Shahu, M.K., Scholten, A., Menke-Sell, S.K., Yamada, H., Koch, K.W., Milhauser, G. and Ames, J.B. (2021) NMR and EPR-DEER Structure of a Dimeric Guanylate Cyclase Activator Protein-5 from Zebrafish Photoreceptors. Biochemistry 60, 3058-3070.

Bartölke, R., Behrmann, H., Görtemaker, K.,Yee, C., Xu, J., Behrmann, E., and Koch, K.-W. (2021) The secrets of cryptochromes: photoreceptors, clock proteins, and magnetic sensors. Neuroforum 27, 151-157.

Ahrens, N., Elbers, D., Greb, H., Janssen-Bienhold, U. and Koch KW. (2021) Interaction of G protein-coupled receptor kinases and recoverin isoforms is determined by localization in zebrafish photoreceptors.  Biochim. Biophys. Acta Mol. Cell. Res.1868(4):118946. doi: 10.1016/j.bbamcr.2020.118946.

Marino, V., Riva, M., Zamboni, D., Koch, K.-W. and Dell'Orco, D. (2021) Bringing the Ca2+ sensitivity of myristoylated recoverin into the physiological range. Open Biol. 11(1):200346. doi: 10.1098/rsob.200346

Souzeau, E., Weisschuh, N., Craig, J.E., Pasutto, F. and Koch, K.-W. (2021) An Assessment of GUCA1C Variants in Primary Congenital Glaucoma. Genes (Basel) 12(3):359. doi: 10.3390/genes12030359. PMID: 33801495.

Rehkamp, A., Tänzler, D., Tüting, C., Kastritis, P.L., Iacobucci, C., Ihling, C.H., Kipping, M., Koch, K.-W. and Sinz, A. (2021) First 3D-Structural Data of Full-Length Guanylyl Cyclase 1 in Rod-Outer-Segment Preparations of Bovine Retina by Cross-Linking/Mass Spectrometry. J. Mol. Biol. 433(10):166947. doi: 10.1016/j.jmb.2021.166947.

Avesani, A., Marino, V., Zanzoni, S., Koch, K.-W. and Dell'Orco, D. (2021) Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R. J. Biol. Chem. Apr 1:100619. doi: 10.1016/j.jbc.2021.100619.

Ahrens N, Aeissen E, Lippe A, Janssen-Bienhold U, Christoffers J, Koch KW. (2021) Farnesylation of Zebrafish G-Protein-Coupled Receptor Kinase Using Bio-orthogonal Labeling. ACS Chem Neurosci. 12(10):1824-1832. doi: 10.1021/acschemneuro.1c00155.

Xu, J., Jarocha, L.E., Zollitsch, T., Konowalczyk, M., Henbest, K.B., Richert, S., Golesworthy, M.J., Schmidt, J., Déjean, V., Sowood, D.J.C., Bassetto, M., Luo, J., Walton, J.R., Fleming, J., Wei, Y., Pitcher, T.L., Moise, G., Herrmann, M., Yin, H., Wu, H., Bartölke, R., Käsehagen, S.J., Horst, S., Dautaj, G., Murton, P.D.F., Gehrckens, A.S., Chelliah, Y., Takahashi, J.S., Koch, K.W., Weber, S., Solov'yov, I.A., Xie, C., Mackenzie, S.R., Timmel, C.R., Mouritsen, H., Hore, P.J. (2021) Magnetic sensitivity of cryptochrome 4 from a migratory songbird. Nature 594(7864):535-540. doi: 10.1038/s41586-021-03618-9.

Beelen, C.J., Asteriti, S., Cangiano, L., Koch, K.W. and Dell’Orco, D. (2021) A hybrid stochastic/deterministic model of single photon response and light adaptation in mouse rods. Comput. Struct. Biotechnol. J. 19, 3720-3734.

Dell'Orco, D., Koch, K.-W. and Rispoli, G. (2021) Where vision begins. Pflugers Arch. Jul 10:1–5. doi: 10.1007/s00424-021-02605-3.

2022

Avesani, A., Bielefeld, L., Weisschuh, N., Marino, V., Mazzola, P., Stingl, K., Haack, T.B., Koch, K.W., and Dell'Orco, D. (2022) Molecular Properties of Human Guanylate Cyclase-Activating Protein 3 (GCAP3) and Its Possible Association with Retinitis Pigmentosa. Int. J. Mol. Sci. 23(6):3240. doi: 10.3390/ijms23063240.

Shahu MK, Schuhmann F, Scholten A, Solov'yov IA, Koch KW. (2022) The Transition of Photoreceptor Guanylate Cyclase Type 1 to the Active State. Int. J. Mol. Sci. 23(7):4030. doi: 10.3390/ijms23074030.

Görtemaker K, Yee C, Bartölke R, Behrmann H, Voß JO, Schmidt J, Xu J, Solovyeva V, Leberecht B, Behrmann E, Mouritsen H, Koch KW. (2022) Direct Interaction of Avian Cryptochrome 4 with a Cone Specific G-Protein. Cells 11(13):2043. doi: 10.3390/cells11132043.

Chen, Y., Bräuer, A.U., Koch, K.W. (2022) Retinal degeneration protein 3 controls membrane guanylate cyclase activities in brain tissue. Front. Mol. Neurosci. 15:1076430.

 

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