Contact
Prof. Dr. Karl-Wilhelm Koch
Tel.: +49-(0)441-798-3640
Office: W4 1-137
E-mail:
2023 - 2024
2023
Yee, C., Görtemaker, K., Wellpott, R., Koch, K.W. (2023) Kinetics of cone specific G-protein signaling in avian photoreceptor cells. Front. Mol. Neurosci. 16:1107025.
Hanić M, Antill LM, Gehrckens AS, Schmidt J, Görtemaker K, Bartölke R, El-Baba TJ, Xu J, Koch KW, Mouritsen H, Benesch JLP, Hore PJ, Solov'yov IA. (2023) Dimerization of European Robin Cryptochrome 4a. J. Phys. Chem B. 127(28):6251-6264.
Koch KW. (2023) Molecular tuning of calcium dependent processes by neuronal calcium sensor proteins in the retina. Biochim. Biophys. Acta. Mol. Cell. Res. 1870(6):119491.
2024
Shahu MK, Schuhmann F, Wong SY, Solov'yov IA, Koch KW. (2024) Allosteric Communication of the Dimerization and the Catalytic Domain in Photoreceptor Guanylate Cyclase. Biochemistry 63(17):2131-2140. doi.org/10.1021/acs.biochem.4c00170
Yee C, Bartölke R, Görtemaker K, Schmidt J, Leberecht B, Mouritsen H, Koch KW. (2024) Comparison of retinol binding protein 1 with cone specific G-protein as putative effector molecules in cryptochrome signalling. Sci Rep.14(1):28326. doi.org/10.1038/s41598-024-79699-z.
Lin Y, Choukrani G, Dubbel L, Rockstein L, Freile JA, Qi Y, Wiersma V, Zhang H, Koch KW, Ammatuna E, Schuringa JJ, van Meerten T, Huls G, Bremer E. (2024) VISTA drives macrophages towards a pro-tumoral phenotype that promotes cancer cell phagocytosis yet down-regulates T cell responses. Exp. Hematol. Oncol. 13(1):35. doi.org/10.1186/s40164-024-00501-x.
Cudia DL, Ahoulou EO, Bej A, Janssen AN, Scholten A, Koch KW, Ames JB. (2024) NMR Structure of Retinal Guanylate Cyclase Activating Protein 5 (GCAP5) with R22A Mutation That Abolishes Dimerization and Enhances Cyclase Activation. Biochemistry doi.org/10.1021/acs.biochem.4c00046 Epub ahead of print. PMID: 38662574.