Prof. Dr. Anja U. Bräuer

Postal address

Faculty VI Medicine and Health Sciences Carl von Ossietzky University Oldenburg Carl-von-Ossietzky Str. 9-11 26129 Oldenburg

Site plan

Insight Anatomy Groningen

Insight into the anatomy



Eymery MC, McCarthy AA§, Hausmann J§. (2023) Linking medicinal cannabis to autotaxin–lysophosphatidic acid signaling. Life Science Alliance 6(2):, 2023.



Chen Y, Bräuer AU, Koch KW. (2022) Retinal degeneration protein 3 controls membrane guanylate cyclase activities in brain tissue. Front Mol Neurosci . 2022 Dec 21;15:1076430. doi: 10.3389/fnmol.2022.1076430. eCollection 2022.

Gray N, Limberg MM, Wiebe D, Weihrauch T, Langner A, Brandt N, Bräuer AU, Raap U. (2022) Differential Upregulation and Functional Activity of S1PR1 in Human Peripheral Blood Basophils of Atopic Patients. Int. J. Mol. Sci. 2022, 23(24), 16117; (registering DOI).

Brandt N, Willmer JP,. Ayon-Olivas MS, Banicka V, Witt M, Wree A, Groß I, Gläser A, Hausmann J, Bräuer AU. (2022) PRG3 and PRG5 C-Termini: Important Players in Early Neuronal Differentiation. Int. J. Mol. Sci. 2022, 23, 13007.

Gross I, Brandt N, Vonk D, Köper F, Wöhlbrand L, Rabus R, Witt M, Heep A, Plösch T, Hipp MS, Bräuer AU. (2022) Plasticity-Related Gene 5 Is Expressed in a Late Phase of Neurodifferentiation After Neuronal Cell-Fate Determination. Front Cell Neurosci. 2022 Apr 15;16:797588. doi: 10.3389/fncel.2022.797588.

Van Bulck M, Brandt N, Claus RA, Graeler M, Braeuer AU (2022). Aβ-Induced Alterations in Membrane Lipids Occur before Synaptic Loss Appears. Int J Mol Sci. 2022 Feb 19;23(4):2300. doi: 10.3390/ijms23042300.

Gray N, Limberg MM, Bräuer AU, Raap U. (2022) Novel functions of S1P in chronic itchy and inflammatory skin diseases. J Eur Acad Dermatol Venereol. 2022 Mar;36(3):365-372. doi: 10.1111/jdv.17764. Epub 2021 Nov 12.


Sakr F, Dyrba M, Bräuer AU, Teipel S (2021). Association of Lipidomics Signatures in Blood with Clinical Progression in Preclinical and Prodromal Alzheimer´s Disease. J Alzheimers Dis. 2021 Dec 9. doi: 10.3233/JAD-201504.

Gross I, Tschigor T, Salman AL, Yang F, Luo J, Vonk D, Hipp MS, Neidhardt J, Bräuer AU (2021).
A systematic expression analysis of Plasticity-Related Genes in mouse brain development brings PRG4 into play. Dev Dyn. 2021 Oct 7. doi: 10.1002/dvdy.428. Online ahead of print. PMID: 34622503.

Baxendale S, Maier EC, Obholzer ND, Burbridge S, Zinski J, Tuazon FB, van Hateren NJ, Garcia Romero MM, Marzo M, Yokoya K, Knight RD, Megason SG, Mullins MC, Whitfield TT. (2023) Bmper is required for morphogenesis of the anterior and posterior semicircular canal ducts in the developing zebrafish inner ear. bioRxiv 2021.06.27.450014; doi:

Sörös P, Wölk L, Bantel C, Bräuer AU, Klawonn F, Witt K (2021) Replicability, Repeatability, and Long-term Reproducibility of Cerebellar Morphometry. Cerebellum. 2021 Jan 9. doi: 10.1007/s12311-020-01227-2. Online ahead of print.

Madadi A, Wolfart J, Lange F, Brehme H, Linnebacher M, Bräuer AU, Büttner A, Freiman T, Henker C, Einsle A, Rackow S, Köhling R, Kirschstein T, Müller S. (2021) Correlation between Kir4.1 expression and barium-sensitive currents in rat and human glioma cell lines. Neurosci Lett. 2021 Jan10;741:135481.doi: 10.1016/j.neulet.2020.135481. Epub 2020 Nov 5.


Lajkó N, Kata D, Szabó M, Mátyás A, Dulka K, Földesi I, Fülöp F, Gulya K, Vécsei L, Mihály A. (2020) Sensitivity of Rodent Microglia to Kynurenines in Models of Epilepsy and Inflammation In Vivo and In Vitro: Microglia Activation is Inhibited by Kynurenic Acid and the Synthetic Analogue SZR104. Int. J. Mol. Sci. 2020, 21, 9333; doi:10.3390/ijms21239333.

Sörös P, Wölk L, Bantel C, Bräuer AU, Klawonn F, Witt K. (2020) Replicability, repeatability, and long-term reproducibility of cerebellar morphometry. bioRxiv 2020: 2020.09.02.279786; doi: 10.1101/2020.09.02.279786.

Brandt N, Löffler T, Fester L,Rune GM (2020) Sex-specific features of spine densities in the hippocampus; Sci Rep 2020 Jul 9;10(1):11405. doi: 10.1038/s41598-020-68371.

Brandt N, Fester L, Rune GM (2020) Neural sex steroids and hippocampal synaptic plasticity; Vitam Horm 2020 Jul 3 114:125-143. doi: 10.1016/bs.vh.2020.06.001.

Gläser A, Hammerl F, Gräler MH, Coldewey SM, Völkner C, Frech MJ, Yang F, Luo J, Tönnies E, von Bohlen Und Halbach O, Brandt N, Heimes D, Neßlauer AM, Korenke GC, Owczarek-Lipska M, Neidhardt J, Rolfs A, Wree A, Witt M, Bräuer AU. (2020) Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism. Int J Mol Sci. 2020 Jun 24;21(12):E4502. doi: 10.3390/ijms21124502.

Yahya I, Boeing M, Pu Q, Puchert M, Ödemis V, Engele J, Brand-Saberi B, Morosan-Puopolo G. CXCR4 and SDF-1 are critically involved in the formation of facial and non-somitic neck muscles. Scientific reports. 2020 10(1): 1-14.

Brandt N, Vierk R, Fester L, Anstötz M, Zhou L, Heilmann LF, Kind S, Steffen P, Rune GM (2019) Sex-specific Difference of Hippocampal Synaptic Plasticity in Response to Neurosteroids; Cereb Cortex 2020 Apr 14;30(4):2627-2641. doi: 10.1093/cercor/bhz265.

Feng X, Yang F, Rabenstein M, Wang Z, Frech M, Wree A, Bräuer AU, Witt M., Gläser A., Hermann A., Rolfs A, Luo J, Stimulation of mGluR1/5 improves defective internalization of AMPA receptors in NPC1 mutant mouse, Cerebral Cortex, 2020 Mar 14.;30(3):1465-1480. doi: 10.1093/cercor/bhz179.

Janach GMS, Reetz O, Döhne N, Stadler K, Grosser S, Byvaltcev E, Bräuer AU, Strauss U. (2020) Interferon-γ acutely augments inhibition of neocortical layer 5 pyramidal neurons. J Neuroinflammation. 2020 Feb 22;17(1):69. doi: 10.1186/s12974-020-1722-y.

Seemann S, Ernst M, Cimmaruta C, Struckmann S, Cozma C, Koczan D, Knospe AM, Haake LR, Citro V, Bräuer AU, Andreotti G, Cubellis MV, Fuellen G, Hermann A, Giese AK, Rolfs A, Lukas J. (2020) Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypes in Fabry disease. Biochem J. 2020 Jan 3.

Wickramasekaraa RN, Bockman C, Hanke J, Schwegler H, McGee J, Walsh E, Yilmazer-Hanke, D (2020). Alpha2-adrenergic dysregulation in congenic DxH recombinant inbred mice selectively bred for a high fear-sensitized (H-FSS) startle response. Pharmacology, Biochemistry and Behavior. 188. 172835. doi: 10.1016/j.pbb.2019.172835.

Gross I, Bräuer AU. (2020) Modulation of LPA Receptor Activity: the key to successful neural regeneration? Neural Regen Res, 2020 15(1):53-54.


Brand I., Groß I., Li D., Zhang Y., Bräuer AU. (2019) Pneumatic conveying printing technique for bioprinting applications. RSCAdv., 2019, 9, 40910: DOI: 10.1039/c9ra07521f.

Breuel S., Vorm M., Bräuer AU., Owczarek-Lipska M., Neidhardt J. (2019) Combining engineered U1 snRNA and antisense oligonucleotides to improve the treatment of a BBS1 splice site mutation, Molecular Therapy - Nucleic Acids, 2019 Aug 16; 18:123-130.

Bräuer AU, Kuhla A, Holzmann C, Wree A, Witt M. (2019) Current Challenges in Understanding the Cellular and Molecular Mechanisms in Niemann-Pick Disease Type C1. Int J Mol Sci., 2019 Sep, 6;20(18).

Brandt N, Rune GM (2019) Sex-dependency of oestrogen-induced structural synaptic plasticity: Inhibition of aromatase versus application of estradiol in rodents; Eur J Neurosci 2019 Aug 12. Doi: 10.1111/ejn.14541

Neßlauer A-M., Gläser A., Gräler M., Engelmann R., Müller-Hilke B., Frank M., Burstein C., Rolfs A., Wree A., Witt M., Bräuer AU. (2019) A therapy with miglustat, 2-hydroxypropyl-ß-cyclodextrin and allopregnanolone restores splenic cholesterol homeostasis in Niemann-Pick Disease Type C1. Lipids Health Dis., 2019 June, 18:146.

Suckau O.*, Gross I.*, Schrötter S., Yang F., Luo J., Wree A., Chun J., Baska D., Baumgart J., Kano K., Aoki J., Bräuer AU. (2019) LPA1, LPA2, LPA4, and LPA6 receptor expression during mouse brain development. Developmental Dynamics, 2019 Mar 8.


Meyer A*, Gläser A*, Bräuer AU, Wree A, Strotmann J, Rolfs A, Witt M. Olfactory performance as an indicator for protective treatment effects in an animal model of neurodegeneration, Front. Integr. Neurosci. 2018 Aug. 12;12:35

Meseke M, Pröls F, Schmahl C, Seebo K, Kruse C, Brandt N, Fester L, Zhou L, Bender R, Rune GM (2018) Reelin and aromatase cooperate in ovarian follicle development; Sci Rep 2018 Jun 7;8(1):8722. doi: 10.1038/s41598-018-26928-x.

Ebner L., Gläser A., Bräuer AU., Witt M., Wree A., Rolfs A., Frank M., Vollmar B., Kuhla A. Evaluation of Two Liver Treatment Strategies in a Mouse Model of Niemann-Pick-Disease Type C1., Int. J. Mol. Sci., 2018 Mar, 19 (4): 972.

2017 and older


Lukas J., Cozma C., Yang F., Kramp G., Meyer A., Eichler S., Neßlauer AM., Böttcher T., Witt M., Bräuer AU., Kropp P., Rolfs A. Glucosylsphingosine Causes Hematological and Visceral Changes in Mice—Evidence for a Pathophysiological Role in Gaucher Disease, Int. J. Mol. Sci. 2017, Oct 20; 18(10).

Bal, G*; Depré F*, Dzamashvili M, Ringel F, Salama A. Effect of thrombopoietin receptor agonists on leucocyte and haematopoietic stem and progenitor cell in peripheral blood of patients with immune thrombocytopenia. Annals of Hematology, 2017. 96(12):2045-2056. doi: 10.1007/s00277-017-3131-6.

Bender RA, Zhou L, Vierk R, Brandt N, Keller A, Gee CE, Schäfer MKE, Rune GM (2016) Sex-dependence of aromatase-mediated synaptic plasticity in the basolateral amygdala; J Neurosci, 2017;37(6):1532-1545.  

von Byern J, Mebs D, Heiss E, Dicke U, Wetjen O, Bakkegard K, Grunwald I, Wolbank S, Mühleder S, Gugerell A, Fuchs H, Nürnberger S. Salamanders on the bench - A biocompatibility study of salamander skin secretions in cell cultures. Toxicon. 2017 Sep 1;135:24-32. doi: 10.1016/j.toxicon.2017.05.02 Epub 2017 May 25.

von Byern J, Grunwald I, Kosok M, Saporito RA, Dicke U, Wetjen O, Thiel K, Borcherding K, Kowalik T, Marchetti-Deschmann M. Chemical characterization of the adhesive secretions of the salamander Plethodon shermani (Caudata, Plethodontidae). Sci Rep. 2017 Jul 27;7(1):6647. doi: 10.1038/s41598-017-05473-z.

Jia B, Huang L, Chen Y, Liu S, Chen C, Xiong K, Song L, Zhou Y, Yang X, Zhong M. A novel contiguous deletion involving NDP, MAOB and EFHC2 gene in a patient with familial Norrie disease: bilateral blindness and leucocoria without other deficits. J Genet. 2017 Dec;96(6):1015-1020.

Yang Y, Zhao Y, Liu X, Chen Y, Liu P*, Zhao L. Effect of SOX2 on odontoblast differentiation of dental pulp stem cells. Mol Med Rep. 2017 Oct 17; 10.3892.


Cecilia B, Seval T, Ulrich R, Lars F, Bal G, Schulz CO, Hemmati P, Renate A, Hanno R, Philipp le C. A Rare Case of Acute Myeloid Leukemia with a t(2;3) Chromosomal Translocation Characterized by Thrombophilia and Chemoresistance. J Clin Exp Hematop. 2016. 2016;56(1):64-8. doi: 10.3960/jslrt.56.64.

Kohn B., Bal G., Chirek A., Rehbein S., Salama A. Romiplostim treatment in dogs as a natural animal model for refractory immune thrombocytopenia. BMC Veterinary Research (2016). 10;12:96. doi: 10.1186/s12917-016-0718-4.

Yilmazer-Hanke D, Eliava M, Hanke J, Schwegler H, Asan E (2016). Density of Acetylcholine Esterase (AchE) and Tyrosine Hydroxylase (TH) Containing Fibers in the Amygdala of Roman High- and Low-Avoidance Rats. Neuroscience letters. 632. 114-8.

Zhao L, Feng Y, Chen X, Yuan J, Liu X, Chen Y, Zhao Y, Liu P*, Li Y. Effects of IGF-1 on neural differentiation of human umbilical cord derived mesenchymal stem cells. Life Sci. 2016 Apr 15;151:93-101.

Liu P, Feng Y, Dong D, Liu X, Chen Y, Wang Y, Zhou Y*. Enhanced renoprotective effect of IGF-1 modified human umbilical cord-derived mesenchymal stem cells on gentamicin-induced acute kidney injury. Sci Rep. 2016 Feb 2; 6:20287.


Neubert J. and Bräuer AU., Superparamagnetic iron oxide nanoparticles: promote neuronal regenerative capacity, Neural Regen Res., 2015 Oct;(10)10:1568-9.

Bal G, Salama, A at all, Identification of novel biomarkers in chronic immune thrombocytopenia (ITP) by microarray-based serum protein profiling. Br J Haematol. (2015)

Klar M., Fenske P., Rezza Vega F., Dame C.*, Bräuer AU.* The transcription factor Yin-Yang 2 alters neuronal outgrowth in vitro, Cell Tissue Res., 2015 Nov;362(2):453-60 .

Pohland M.*, Glumm R.*, Stoenica L., Höltje M., Kiwit J., Ahnert-Hilger G., Strauss U., Bräuer AU., Paul F., Glumm J. Studying axonal outgrowth and regeneration of the corticospinal tract in organotypic slice cultures, J. Neurotrauma, 2015, 7:14.

Neubert J., Wagner S., Kiwit J., Bräuer AU.*, Glumm J.*. Effects of different superparamagnetic iron oxide nanoparticles on murine primary brain cells. International Journal of Nanomedicine, 2015, 10, 2033-2049.

Fester L, Brandt N, Windhorst S, Pröls F, Bläute C, Rune GM (2015) Control of aromatase in hippocampal neurons. J Steroid Biochem Mol Biol. 2015 Oct12.  pii: S0960-0760(15)30109-6. doi: 10.1016/j.jsbmb.2015.10.009. Review.

Koester JD, Leggewie B, Blechner C, Brandt N, Fester L, Rune GM, Schweizer M, Kindler S, Windhorst S (2015) Inositol, 1,4,5- triphosphate-3kinase-A controls morphology of hippocampal dendritic spines. Cell Signal. 2015 Oct 28. pii: S0898-6568(15)00309-5. doi: 10.1016/j.cellsig.2015.10.016.

Reetz J., Hildebrandt S., Schmidt A., Meier C., Herchenroder O., Gläser A., Witt M., Pützer BM., Wree A., Novel subventricular zone early progenitor cell-specific adenovirus for in vivo therapy of central nervous system disorders reinforces brain stem cell heterogeneity, Brain structure & function, 2015 May, 221 (4): 2049-59.

Lukas J., Pockrandt A., Seemann S., Sharif M., Runge F., Pohlers S., Zheng C., Gläser A., Beller M., Rolfs A., Giese A., Enzyme Enhancers for the treatment of Fabry and Pompe Disease, Molecular Therapy, 2015 Mar, 23 (3): 456-464.

Liu P, Cai J, Dong D, Chen Y, Liu X, Wang Y, Zhou Y*. Effects of SOX2 on Proliferation, Migration and Adhesion of Human Dental Pulp Stem Cells. PLoS One. 2015 Oct 23;10(10).


Maier EC, Whitfield T.: RA and FGF signalling are required in the zebrafish otic vesicle to pattern and maintain ventral otic identities, PLoS Genetics 2014 Dec 4;10(12).

Coiro P., Stoenica L., Strauss U., Bräuer AU. Plasticity-related gene 5 expression promotes spine formation in primary neurons. J Biol Chem, 2014, July 29.

Kamhieh-Milz J, Moftah RF, Bal G, Futschik M, Sterzer V, Khorramshahi O, Burow M, Thiel G, Stuke-Sontheimer A, Chaoui R, Kamhieh-Milz S, Salama A. Differentially expressed microRNAs in maternal plasma for the noninvasive prenatal diagnosis of Down syndrome (trisomy 21). Biomed Res Int. (2014).

Browne C, Hanke J, Rose C, Walsh I, Foley T, Clarke G, Schwegler H, Cryan J, Yilmazer-Hanke D (2014). Effect of Acute Swim Stress on Plasma Corticosterone and Brain Monoamine Levels in Bidirectionally Selected DxH Recombinant Inbred Mouse Strains Differing in Fear Recall and Extinction. Stress (Amsterdam, Netherlands). 17. 1-36.

Maier EC, Saxena A, Alsina B, Bronner ME, Whitfield T: Sensational placodes: Neurogenesis in the otic and olfactory system, Dev Biol. 2014 May 1;389(1).

Hübner A., Derkow K., Bräuer AU. Efficient isolation of CD8a positive T cells from postnatal mice using a combined MACS approach. J Immunol Methods, 2014  Apr:406: 110 116.

Rupprecht A., Sittner D., Smorodchenko A., Hilse K., Goyn J., Moldzio R., Seiler A., Bräuer AU., Pohl EE. Uncoupling protein 2 and 4 expression pattern during stem cell differentiation provides new insight in their putative function. PLOS One, 2014 Feb. 11; 9 (2): e88474.

Masyuk M, Abduelmula A, Morosan-Puopolo G, Ödemis V, Rehimi R, Khalida N, Yusuf F, Engele J, Tamamura H, Theiss C, Brand-Saberi B.: Retrograde migration of pectoral girdle muscle precursors depends on CXCR4/SDF-1 signaling. Histochem Cell Biol. 2014;142(5):473-88

Brandt N, Vierk R, Fester L, Zhou L, Imholz P, Rune GM (2014) Gender and the effects of steroid hormones in the central nervous system. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2014 Sep;57(9):1054-60. doi: 10.1007/s00103-014-2014-4. German.

Vierk R, Brandt N, Rune GM (2014) Hippocampal estradiol synthesis and its significance for hippocampal synaptic stability in male and female animals. Neuroscience. 2014 May 15;274C:24-32. doi: 10.1016/j.neuroscience.2014.05.003. Review.

Zhou L, Fester L, Haghshenas S, de Vrese X, Hacht RV, Gloger S, Brandt N, Bader M, Vollmer G, Rune GM (2014) Oestradiol-induced synapse formation in the female hippocampus: roles of estrogen receptor subtypes. J Neuroendocrinol. 2014 Apr 30. doi: 10.1111/jne.12162.


Velmans T., Battefeld A., Geist B., Soriguera Farrés A., Strauss U., Bräuer AU. Plasticity related gene-3 promotes neurite shaft protrusion. BMC Neuroscience, 2013 Mar 19;14:36.

Browne C, Clarke G, Hanke J, G Dinan T, Schwegler H, Yilmazer-Hanke D, Cryan J (2013). Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain. Behavioural brain research. 236. 283-8.

Lipfert J., Ödemis V., Wagner DC., Boltze J., Engele J.: CXCR4 and CXCR7 form a functional receptor unit for SDF-1/CXCL12 in primary rodent microglia. Neuropathol Appl Neurobiol. 2013; 39(6): 667-80.

Lipfert J., Ödemis V., Engele J.: Grk2 is an Essential Regulator of CXCR7 Signalling in Astrocytes. Cell Mol Neurobiol 2013; 33(1): 111-8.

Prange-Kiel J, Schmutterer T, Fester L, Zhou L, Imholz P, Brandt N, Vierk R, Jarry H, Rune GM (2013) Endocrine regulation of estrogen synthesis in the hippocampus? Prog Histochem Cytochem. 2013 Jul 29. doi:pii: S0079-6336(13)00013-2. 10.1016/j.proghi.2013.07.002.

Brandt N, Vierk R, Rune GM (2013) Sexual dimorphism in estrogen-induced synaptogenesis in the adult hippocampus. Int J Dev Biol. 2013;57(5):351-6. doi: 10.1387/ijdb.120217gr.

Strauss U. and Bräuer AU. Current views on regulation and function of plasticity-related genes (PRGs/LPPRs) in the brain. BBA – Molecular and Cell Biology of Lipids. Special Issue: Lysophospholipids, Biochim Biophys Acta., 2013 Jan;1831(1):133-8.


Rupprecht A., Bräuer AU., Smorodchenko A., Goyn J., Hilse KE., Shabalina IG., Infante-Duarte C., and Pohl EE. Quantification of uncoupling protein 2 reveals its main expression in immune cells and selective up-regulation upon T-cell proliferation. PLOS One, 2012;7(8):e41406.

Stadler K., Bierwirth C., Stoenica L., Battefeld A., Reetz O., Mix E., Schuchmann S., Velmans T., Rosenberger K., Bräuer AU., Lehnardt S., Nitsch R., Budt M., Wolff T., Kole MH., Strauss U., Elevation in type I interferons inhibits HCN1 and slows cortical neuronal oscillations. Cerebral Cortex, 2012 Oct 4.

Bal G, Kamhieh-Milz J, Sterzer V, Al-Samman M, Debski J, Klein O, Kamhieh-Milz S, Bhakdi S, Salama, A. Proteomic profiling of secreted proteins for the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells.  Cell Transplant. (2012).

Kamhieh-Milz J, Bal G, Sterzer V, Kamhieh-Milz S, Arbach O, Salama A. Reduced antioxidant capacities in platelets from patients with autoimmune thrombocytopenia purpura (ITP) Platelets (2012).

Rose C, Schwegler H, Hanke J, Yilmazer-Hanke D (2012). Pregnancy rates, prenatal and postnatal survival of offspring, and litter sizes after reciprocal embryo transfer in DBA/2JHd, C3H/HeNCrl and NMRI mice. Theriogenology. 77. 1883-93.

Battefeld A., Rocha N., Stadler K., Bräuer AU., and Strauss U., Distinct Perinatal Features of the Hyperpolarization-Activated Non-Selective cation current Ih in the rat cortical plate. Neural Development, 2012 Jun 13; 7(1):21.

Vogt J., Glumm R., Schlüter L., Schmitz D., Rost BR., Streu N., Rister B., Suman Bharathi B., Gagiannis D., Hildebrandt H., Weinhold B., Mühlenhoff M., Naumann T., Savaskan NE., Bräuer AU., Reutter W., Heimrich B.*, Nitsch R.* and Horstkorte R*. Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting, Cell Mol Life Sci, 2012 Apr;69(7):1179-91.

Hunger C., Ödemis V., Engele J.: Expression and function of the SDF-1 chemokine receptors CXCR4 and CXCR7 during limb muscle development and regeneration. Exp. Cell Res. 2012; 318: 2178–2190.

Glisic D., Lehmann C., Figiel F., Ödemis V., Lindner R., Engele J.: A novel cross-talk between endothelin and ErbB receptors controlling glutamate uptake into astrocytes. J Neurochem. 2012; 122(4): 844-55.

Ödemis V., Lipfert J., Kraft R., Hajek P., Abraham G., Hattermann K., Mentlein R., Engele J.: The presumed atypical chemokine receptor CXCR7 signals through Gi/o proteins in primary rodent astrocytes and human glioma cells. Glia 2012; 60 (3): 372–381.

Vierk R, Glassmeier G, Zhou L, Brandt N, Fester L, Dudzinski D, Wilkars W, Bender RA, Lewerenz M, Gloger S, Graser L, Schwarz J, Rune GM (2012) Aromatase inhibition abolishes LTP generation in female mice by destabilizing the spine cytoskeleton. J Neurosci, 2012. 

Wilkars W, Liu Z, Lewis AS, Stoub TR, Ramos EM, Brandt N, Nicholson DA, Chetkovich DM, Bender RA (2012) 1. Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms. PLoS One. 2012;7(2):e32181. Epub 2012 Feb 21.


Braun D., Kinne A., Bräuer AU., Sapin R., Klein MO., Köhrle J., Wirth EK.*, Schweizer U.*, Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells, Glia, 2011 Mar;59(3):463-71.

Maier E, Nord H, von Hofsten J, Gunhaga L.: A balance of BMP and Notch activity regulates neurogenesis and olfactory nerve formation, PLoS ONE, 2011 Feb 23;6(2).

Bal G, Kamhieh-Milz J, Futschik M, Haupl T, Salama A, Moldenhauer A. Transcriptional profiling of the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells (HUVECs). Cell Transplant. (2011).

Moldenhauer A, Futschik M, Lu H, Helmig M, Götze P, Bal G, Zenke M, Han W,Salama A. Interleukin 32 promotes hematopoietic progenitor expansion and attenuates bone marrow cytotoxicity. Eur J Immunol. (2011)


Wierschke S., Gigout S., Horn P. Lehmann TN., Dehnicke C., Bräuer AU.* and Deisz RA.*, Evaluating reference genes to normalize gene expression in human epileptogenic brain tissues, Biochem. Bioph Res Co., 2010 Dec 17;403(3-4):385-390.

Ödemis V., Boosmann K., Küry P., Engele J.: CXCR7 is an active component of SDF-1 signalling in astrocytes and Schwann cells. J. Cell. Sci. 2010; 123(Pt 7): 1081-8.

Göttle P., Kremer D., Jander S., Ödemis V., Engele J., Hartung HP, Küry P.: Activation of CXCR7 receptor promotes oligodendroglial cell maturation. Ann Neurol. 2010 Dec; 68(6): 915-24.

Maier E, von Hofsten J, Nord H, Fernandes M, Paek H, Hébert JM, Gunhaga L.: Opposing activities of FGF and BMP specify respiratory versus sensory olfactory epithelial cell fate decisions, Development. 2010 May;137 (10). (recommended by F1000).


D.N. Brindley and A.U. Bräuer Chapter 12 Lipid Mediators and Modulators of Neuronal Function: Lysophosphatidate and Lysolipids Handbook of Neurochemistry and Molecular Neurobiology, Neural Lipids, 2010, Part 3, 289-310, DOI: 10.1007/978-0-387-30378-9_12, A. Lajtha, G. Tettamanti, & G. Goracci (eds.)


Maier E, Gunhaga L: Dynamic expression of neurogenic markers in the developing chick olfactory epithelium, Dev Dyn. 2009, Jun;238(6).

Kühbacher M., Bartel J., Hoppe B., Alber D., Bukalis G., Bräuer AU., Behne D., Kyriakopoulos A. The brain selenoproteome: Priorities in the hierarchy and different levels of selenium homeostasis in the brain of selenium deficient rats, J Neurochem., 2009 Apr 21.

Frisch C, Hanke J, Kleinerüschkamp S, Roesk S, Kaaden S, Elger C, Schramm J, Yilmazer-Hanke D, Helmstaedter C (2009). Positive Correlation Between the Density of Neuropeptide Y Positive Neurons in the Amygdala and Parameters of Self-Reported Anxiety and Depression in Mesiotemporal Lobe Epilepsy Patients. Biological psychiatry. 66. 433-40.

Trimbuch T.*, Beed P.*, Vogt J.*, Schuchmann S., Maier N., Kintscher M., Breustedt J., Schuelke M., Streu N., Kieselmann O., Brunk I., Laube G., Strauss U., Battefeld A., Wende H., Birchmeier C., Wiese S., Sendtner M., Kawabe H., Kishimoto-Suga M., Brose N., Baumgart J., Geist B., Aoki J., Savaskan NE., Bräuer AU., Chun J., Ninnemann O., Schmitz D.*, Nitsch R.* HHSynaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signalingHH, Cell, 2009 Sep 18, 138 (6):1222-35.

Wirth EK*, Roth S*, Blechschmidt C, Hölter S, Becker L, Racz I, Durner VG, Fuchs H, Naumann T, Bräuer AU, Köhrle J, Grüters A, Schweizer U. HHNeuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndromeHH, J. Neurosci., 2009 Jul. 29; 29(30):9439-49.

Smorodchenko A.*, Rupprecht A.*, Sarilova I., Ninnemann O., Bräuer AU., Franke K., Schumacher S., Techritz S., Nitsch R., Schuelke M., Pohl EE. Comparative analysis of uncoupling protein 4 distribution in various tissues under physiological conditions and during development, BBA-Biomembranes, 2009 Oct; 17888(10):2309-19.

Drews D., Klar M., Dame C*, Bräuer AU.*, Developmental expression profile of the yy2 gene in mice, BMC Dev Biol. 2009 Jul 28; 9:45.


Hoppe B.*, Bräuer AU.*, Kühbacher M., Savaskan NE., Behne D. and Kyriakopoulos A. Biochemical analysis of the selenoprotein expression in brain cell lines and in distinct brain regions Cell Tissue Res, 2008 Jun. 332(3): 403-414.

Moldenhauer A, Genter G, Lun A, Bal G, Kiesewetter H, Salama A. Hematopoietic progenitor cells and interleukin-stimulated endothelium: expansion and differentiation of myeloid precursors. BMC Immunol. (2008).

Rose C, Röhl FW, Hanke J, Schwegler H, Yilmazer-Hanke D (2008). Maternal and Genetic Effects on the Acoustic Startle Reflex and its Sensitization in C3H/HeN, DBA/2JHd and NMRI Mice Following Blastocyst Transfer. Behavior genetics. 38. 596-611.

Nürnberg A., Bräuer AU., Wettschureck N., and Offermanns S. Antagonistic regulation of neurite morphology through Gq/g11 and G12/G13, J Biol Chem, 2008 Dec. 19; 283 (51): 35526-35531.

Kolodziej A., Schulz S., Guyon, A., Wu D.F., Pfeiffer M., Ödemis V., Hollt V., Stumm R.:Tonic Activation of CXC Chemokine Receptor 4 in Immature Granule Cells Supports Neurogenesis in the Adult Dentate Gyrus. J. Neuroscience. 2008; 28 (17): 4488-4500.

Brandt N, Franke K, Johannes S, Buck F, Harder S, Hassel B, Nitsch R, and Schumacher S (2008) B56b, a regulatory subunit of protein phosphatase 2A, interacts with CALEB/NGC and inhibits CALEB/NGC-mediated dendritic branching. FASEB J, 2008 Jul;22(7):2521-33. Epub 2008 Apr 2.

Bräuer AU
and Nitsch R. Plasticity-related genes (PRGs/LRPs): A brain-specific class of lysophospholipid-modifying proteins. BBA – Molecular and Cell Biology of Lipids. Special Issue: Lysophospholipids, Biochim Biophys Acta., 2008 Sep;1781(9):595-600.


Kole MH, Bräuer AU, and Stuart GJ. Inherited cortical HCN1 channel loss amplifies dendritic calcium electrogenesis and burst firing in a rat absence epilepsy model. J. Physiol., Jan., 15, 578 (Pt 2): 507-525, 2007.

Emmerich F*, Bal G*, Barakat A, Milz J, Mühle C, Martinez-Gamboa L, Dörner T, Salama A. High-level serum B-cell activating factor and promoter polymorphisms in patients with idiopathic thrombocytopenic purpura. Br J Haematol. (2007)

Savaskan NE, Rocha L, Kotter MR, Baer A, Lubec G, van Meeteren LA, Kishi Y, Aoki J, Moolenaar WN, Nitsch R, and Bräuer AU. Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma. Cell Mol Life Sci, Jan, 64(2): 230-243, 2007.

Savaskan NE, Borchert A, Bräuer AU and Kühn H. A role for glutathione peroxidase-4 in brain development and neuronal apoptosis. Free Radical Bio Med, Jul. 15; 43(2): 191-201, 2007.

Dalla Puppa L., Savaskan NE., Bräuer AU, Behne D. and Kyriakopoulos A. The role of selenite on microglia migration. Ann NY Acad. Sci., Jan 1096: 179-183, 2007.

Ödemis V., Boosmann K., Dieterlen MT, Engele J.: The chemokine SDF-1 controls multiple steps of myogenesis through atypical PKCzeta. J. Cell. Sci. 2007; 120(Pt 22): 4050-9.

Brandt N, Franke K, Rasin MR, Baumgart J, Vogt J, Khrulev S, Hassel B, Pohl EE, Sestan N, Nitsch R, and Schumacher S (2007) The neural EGF family member CALEB/NGC mediates dendritic tree and spine complexity. EMBO J 26, 2371-2386.


Schridde U*, Strauss U*, Bräuer AU*, and van Luijtelaar G. Environmental manipulations early in development alter seizure activity, Ih and HCN1 protein expression later in life. Eur J Neurosci., 23(12):3346-3358, 2006.

Peeva GP*, Angelova SK*, Guntinas-Lichius O, Streppel M, Irintchev A*, Schütz U, Popratiloff A, Savaskan NE, Bräuer AU, Alvanou A, Nitsch R, and Angelov DN*. Improved outcome of facial nerve repair in rats is associated with enhanced regenerative response of motoneurons and augmented neocortical plasticity. Eur J Neurosci., 24 (8): 2152-2162, 2006.

Rose C, Schwegler H, Hanke J, Röhl FW, Yilmazer-Hanke D (2006). Differential effects of embryo transfer and maternal factors on anxiety-related behavior and numbers of neuropeptide Y (NPY) and parvalbumin (PARV) containing neurons in the amygdala of inbred C3H/HeN and DBA/2J mice. Behavioural brain research. 173. 163-8.

Nordström U, Maier E, Jessell TM, Edlund T: An early role for Wnt signalling in specifying neural patterns of Cdx and Hox gene expression and motor neuron subtype identity, PLoS Biol. 2006, Jul 18;4(8).

Rose C, Röhl FW, Schwegler H, Hanke J, Yilmazer-Hanke D (2006). Maternal and Genetic Effects on Anxiety-Related Behavior of C3H/HeN, DBA/2J and NMRI Mice in a Motility-Box Following Blastocyst Transfer. Behavior genetics. 36. 745-62.


Schäfer M., Bräuer AU, Savaskan NE, Rathjen FG, and Brümmendorf T. Neurotractin/Kilon promotes neurite outgrowth and is expressed on reactive astrocytes after entorhinal cortex lesion. Mol Cell Neurosci., 29(4):580-90, 2005.

Bajorat R, Bräuer AU, Wasner U, Rolfs A, and Strauss U. Functional significance of HCN2/3 mediated Ih in striatal cells at early developmental states. J Neurosci. Res. 82 (2):206-13, 2005.

Ödemis V., Lamp E., Pezeshki G., Moepps B., Schilling K., Gierschik P., Littman DR, Engele J.: Mice deficient in the chemokine receptor CXCR4 exhibit impaired limb innervation and myogenesis. Mol. Cell. Neurosci. 2005; 30(4): 494-505.

Roskoden T, Hanke J, Yilmazer-Hanke D, Schwegler H (2005). Reduced number of CRF-containing neurons in the central amygdala correlated with enhanced locomotor activity following early postnatal corticosterone treatment in the Wistar rat. Behavioural brain research. 165. 221-8.


Strauss, U.*, Kole MH.*, Bräuer AU., Pahnke J., Bajorat R., Rolfs, A., Nitsch R., and Deisz RA. An impaired neocortical Ih is associated with enhanced excitability and epilepsy. Eur J Neurosci. Jun;19(11):3048-58, 2004.

Bräuer, AU., Nitsch R. and Savaskan NE. Identification of macrophage/ microglia activation factor (MAF) associated with late endosomes/lysosomes in microglial cells. FEBS Lett., 9;563(1-3):41-8, 2004.

Meier, S., Bräuer, AU., Heimrich, B., Nitsch, R. and Savaskan, NE. Myelination in the hippocampus during development and following lesion. Cell Mol Life Sci, 61(9):1082-94, 2004.

Savaskan, NE*, Bräuer, AU*, and Nitsch, R. Molecular cloning and expression regulation of PRG-3, a new member of the plasticity-related gene family. Eur J Neurosci., 19(1):212-20, 2004.

Wendik B, Maier E, Meyer D: Zebrafish mnx genes in endocrine and exocrine pancreas formation, Dev Biol. 2004, Apr 15;268(2).

Bräuer AU.*, Savaskan NE.*, Kühn H., Prehn S., Ninnemann O., and Nitsch R. Is PRG1 a new lipid phosphatase? Nat Neurosci Comment, 7 (8), 2004.

Yilmazer-Hanke D, Hantsch, M, Hanke J, Schulz C, Faber-Zuschratter H, Schwegler H (2004). Neonatal thyroxine treatment: Changes in the number of corticotropinreleasing-factor (CRF) and neuropeptide Y (NPY) containing neurons and density of tyrosine hydroxylase positive fibers (TH) in the amygdala correlate with anxiety-related behavior of Wistar rats. Neuroscience. 124. 283-97.

Hanke J, Sabel B (2004). L-type calcium channel antagonist nifedipine reduces neurofilament restitution following traumatic optic nerve injury. Acta neurochirurgica. Supplement. 89. 75-80.

Bräuer AU. and Savaskan NE. Molecular actions of selenium in the brain: neuroprotective mechanisms of an essential trace element. Rev Neuroscience; 2004 15(1):19-32.

Schweizer, U., Bräuer AU., Köhrle J., Nitsch R., and Savaskan NE. Selenium and brain function: a poorly recognized liaison. Brain Res Brain Res Rev., 2004 Jul;45(3):164-78.


Bräuer, AU., Savaskan, NE., Plaschke, M, Ninnemann, O. and Nitsch, R. The role of CCK in the course of de- and regeneration after lesion in the hippocampus: molecular evidence revealed by differential display-RT-PCR. Neuroscience;121(1):111-21, 2003.

Bräuer AU.*, Savaskan NE.*, Kühn H., Prehn S., Ninnemann O., and Nitsch R. A new phospholipid phosphatase, PRG-1 is involved in axonal growth and regenerative sprouting. Nat Neurosci., 6(6):572-8, 2003.

Eyüpoglu, IY.*, Savaskan, NE.*, Bräuer, AU.*, Nitsch, R. and Heimrich, B. Identification of neuronal cell death in a model of degeneration in the hippocampus. Brain Res Brain Res Protoc, 11(1):1-8, 2003.

Savaskan, NE.*, Bräuer, AU.*, Kühbacher, M., Eyüpoglu, IY., Kyriakopoulos, A., Ninnemann, O., Behne, D. and Nitsch, R. Selenium dificiency increases susceptibility for glutamate-unduced excititoxicity. FASEB J, 17(1):112-4, 2003

Meier, S., Bräuer, AU., Heimrich B., Schwab, M., Nitsch, R. and Savaskan, NE. Molecular analyses of Nogo genes in the hippocampus during development and following lesion. FASEB J, 17(9):1153-5, 2003.


Ödemis V., Moepps B., Gierschik P., Engele J.: Interleukin-6 and cAMP induce stromal cell-derived factor-1 chemotaxis in astroglia by up-regulating CXCR4 cell surface expression. Implications for brain inflammation. J. Biol. Chem. 2002; 277(42): 39801-8.

Hanke J, Sabel B (2002). Anatomical correlations of intrinsic axon repair after partial optic nerve crush in rats. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 184. 113-23.


Bräuer, AU.*, Savaskan, NE.*, Plaschke, M., Ninnemann, O. and Nitsch, R. Perforant path lesion induces up-regulation of stathmin mRNA, but not SCG10 mRNA, in the adult rat hippocampus. Neuroscience; 102 (3): 515-11126, 2001.

Bräuer, AU.*, Savaskan, M.*, Kole, MHP.*, Plaschke, M., Monteggia, L., Nestler, E., Simbürger, E., Deisz, R., Ninnemann, O. and Nitsch, R. Molecular and functional analysis of hyperpolarization-activated pacemaker channels in the hippocampus after entorhinal cortex lesion. FASEB J; 15: 2689-2701, 2001.

Hanke J (2001): Apoptosis in cultured islets of Langerhans and occurrence of Bcl-2, Bak, Bax, Fas and FasL. Cell Tissues Organs 169: 113-124.


Savaskan, NE.*, Eyüpoglu, IY*, Bräuer, AU.*, Plaschke, M., Ninnemann, O., Nitsch, R. and Skutella T. Entorhinal cortex lesion studied with the novel dye fluoro-jade. Brain Res. May 2; 864(1): 44-51, 2000.

Bräuer, AU.*, Savaskan, NE.*, Plaschke, M., Prehn, S., Ninnemann, O. and Nitsch, R. IG-molecule Kilon shows differential expression pattern from LAMP in the developing and adult rat hippocampus. Hippocampus 10(6): 632-44, 2000.

Savaskan, NE.*, Skutella, T.*, Bräuer, AU., Plaschke, M., Ninnemann, O. and Nitsch, R. Outgrowth-promoting molecules in the adult hippocampus after perforant path lesion. Eur J Neurosci. Mar; 12(3): 1024-32, 2000.

Hanke J (2000) Apoptosis and occurrence of Bcl-2, Bak, Bax, Fas and FasL in the developing and adult rat endocrine pancreas. Anat Embryol 202: 303-312.


Yilmazer-Hanke D, Hanke J (1999): Progression of Alzheimer-related neuritic plaque pathology in the entorhinal region, perirhinal cortex, and hippocampal formation. Dement Geriatr Cogn Disord 10: 70-76.


Nagy Z, Yilmazer DM, Braak H, Braak E, Schultz C, Hanke J (1998): Assessment of the pathological stages of Alzheimer’s disease in thin paraffin sections: A comparative study. Dement Geriatr Cogn Disord 9: 140-144.

Ruf S., Ödemis V., Thasler W., Babl-Weisbarth M., Rose C.: Therapie der Pyoderma fistulans sinifica., Zbl Chir 1998;123:601.


Evers B., Gerngroß H., Ödemis V.: Tourniquetischämie und intramuskulärer Sauerstoffpartialdruck bei Kniegelenksarthroskopien. In: Hartel W. (eds) Klinik und Forschung in der Chirurgie unter dem Aspekt von Effizienz und Ökonomie. Langenbecks Archiv für Chirurgie, vol 1997. Springer, Berlin, Heidelberg.

Evers B., Ödemis V., Gerngross H.: Intramuscular oxygen partial pressure in patients with chronic exertional compartment syndrome (CECS). Adv. Exp. Med. Biol. 1997; 428: 311-316.

Evers B., Ödemis V., Gerngross H.: Oxygen partial pressure in the anterior tibial muscle during and after knee surgery with tourniquet control. Adv. Exp. Med. Biol. 1997; 428: 317-325.

Nagy Z, Vatter-Bittner B, Braak H, Braak E, Yilmazer DM, Schultz C, Hanke J (1997): Staging of Alzheimer-type pathology: An interrater-intrarater study. Dement Geriatr Cogn Disord 8: 248-251.

Hanke J, Yilmazer-Hanke DM (1997): Pigmentarchitectonic subfields of the entorhinal region as revealed in tangential sections. J Brain Res 38: 427-432.

Hanke J, Yilmazer-Hanke DM (1997): Variabilities in the distribution of neurofibrillary tangles in the anterior parahippocampal gyrus at initial stages of Alzheimer’s disease. Clin. Neuropathol 16: 299-302.

Hanke J (1997): Sulcal pattern of the anterior parahippocampal gyrus in the human adult. Ann Anat 179: 335-339.

Hanke J, Willig A, Yinon U, Jaros PP (1997): Delta and kappa opioid receptors in eyestalk ganglia of a crustacean. Brain Res. 744: 279-284.


Hanke J, Willig A, Jaros PP (1996): Opioid receptor types for endogenous enkephalin in the thoracic ganglion of the crab, Carcinus maenas. Peptides 17: 965-972.


Hanke J, Jaros PP, Willig A (1993): Ultrastructural autoradiographic localization of opiod receptors on membranes with CHH immunogold detected axon terminals in a neurohemalorgan of Carcinus maenas L.. Histochem. 99: 405-410.


Hanke J, Jaros PP, Willig A (1992): Differential localization of leu-enkephalin in axon terminals of the sinus gland of the crabs Carcinus maenas L., Eriocheir sinensis and Uca pugilator. Cell Tissue Res. 270: 521-526.

*Contributed equally as first or senior author.


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