PD Dr. Carsten Dosche
Lead Scientist

+49 (0) 441 798 3975

+49 (0) 441 798 3979

Prof. Dr. Gunther Wittstock
Team Leader

+49 (0) 441 798 3970

+49 (0) 441 798 3979

Mailing Address

University of Oldenburg
School of Mathematics
   and Science
Institute of Chemistry
Wittstock Group
D-26111 Oldenburg


University of Oldenburg
Campus Wechloy
Carl-von-Ossietzky Street 9-11
Building W3, 1st floor
D-26129 Oldenburg

How to find us

Single Molecule Spectroscopy

Single Molecule Spectroscopy


Contact person is Dr. Carsten Dosche


Single molecule spectroscopy has become a important tool in chemistry and biology since about 2000. Various methods of superresolution microscopy, for which the Nobel prize was awarded in 2014, make use of single molecule spectroscopy. In contrast to other spectroscopic techniques that probe an ensemble of molecules (i.e., molecules in slight different environments and states), single molecule spectroscopy obtains data from a single molecule for which the environment changes only slowly (as fast as the molecule can change location). In this way subpopulation of molecules in different states can be distinguished. Applications are in the area of distance mesurements in proteins, size determination of colloids (nanoparticles and micells) as well as kinetc studies of (photo)electrochemical reactions in ns to ms time domains.

The instrumentation required for single molecules spectroscopy also allows measurements of time-resolved fluorescence spectroscopy, fluorescence anisotropy and spectroelectrochemistry. This will be used in ongoing projects for imaging of special distribution of electrochemically generated reagents.

(Changed: 19 Jan 2024)  | 
Zum Seitananfang scrollen Scroll to the top of the page