See Virology subpage

• Optimization of ESBL and carbapenemase detection algorithms
• Natural competence of clinical Enterobacterales isolates
• Characteristics of natural Proteus spp.

• Application of evolutionary principles to combat the development of resistance
• Evolution experiments in the laboratory and individual-based simulations
• Determinants of evolvability in the context of antibiotic resistance
• Mutation rates and horizontal gene transfer
• Linking evolution and epidemiology
• Secondary interest: Invertebrate paleontology

• Epidemiology of antibiotic-resistant bacteria in the northern Dutch-German border region
• Antibiotic susceptibility testing of carbapenemase-producing Enterobacterales

• Innate immunity and interferon-stimulated genes (ISGs)
• Hepatitis E virus (HEV) infection in humans and pigs
• Characterization of novel host restriction factors against HEV

• Innate immunity and interferon-stimulated genes (ISG)
• Regulation of retrotransposons