Publications
Publications
2025
Afghah T, Heeren J, Hartog L, Biermann P, Wulff A, Warzybok A, Wagener KC. An open-access dataset of unaided and hearing aid-assisted auditory perception measures in complex virtual acoustic scenes. Int J Audiol. 2025 Dec 28:1-14. doi: 10.1080/14992027.2025.2601653. Epub ahead of print. PMID: 41457412.
Biermann P*, Baier C*, Vietor AC, Zacher B, Baumgartl T, von Landesberger T, Behnke M, Storck M, Petzold M, Kaase M; HiGHmed lnfection Control Study Group; Schlüter D, Marschollek M*, Scheithauer S*, Wulff A*. An openEHR based infection control system to support monitoring of nosocomial bacterial clusters and contacts. NPJ Digit Med. 2025 Jun 30;8(1):385. doi: 10.1038/s41746-025-01795-9.
Böhm-Hustede AK, Lubasch JS, Hoogestraat AT, Buhr E, Wulff A. Barriers and facilitators to the implementation and adoption of computerised clinical decision support systems: an umbrella review protocol. Syst Rev. 2025 Jan 2;14(1):2. doi: 10.1186/s13643-024-02745-4. PMID: 39748437; PMCID: PMC11697958.
Golub, Yulia; Wulff, Antje; Plösch, Torsten (2025): From haze to horizon: epigenetic research and artificial intelligence in child and adolescent psychiatry. In: European Child & Adolescent Psychiatry. https://doi.org/10.1007/s00787-025-02686-w
McGee F, Sin MA, Chen M, Ebert D, Misue K, Ritsos PD, Wulff A, Tory M, Keefe D. Preparedness for Visualisation in the Next Pandemic. IEEE Comput Graph Appl. 2025 May-Jun;45(3):95-103. doi: 10.1109/MCG.2025.3561619. PMID: 40690357.
Hoogestraat AT, Schmitz T, Voigt A, Baumgartl T, Müller F, Biermann P, Risk Principe Study Group, von Landesberger T, Wulff A. Developing a User-Centric System for Hospital-Onset Bacteremia Risk Assessment and Visualisation: An Integrated Requirements Analysis Approach. Stud Health Technol Inform. 2025 Apr 24;324:51-56. doi: 10.3233/SHTI250160
Kesselmeier M, Hoogestraat AT, Baumgartl T, Bludau A, Boenniger MM, Marquet M, Naim J, Reinoso-Schiller N; RISK PRINCIPE Study Group; Hagel S, Schmitz T, Spreckelsen C, Uschmann S, Wiesenfeldt M, Von Landesberger T, Wulff A, Pletz M, Scheithauer S, Scherag A, Marschollek M. Potential Risk Factors for Hospital-Onset Bloodstream Infections - Initial Findings Within the RISK PRINCIPE Project for Data-Driven Clinical Decision Support. Stud Health Technol Inform. 2025 Aug 7;329:1656-1657. doi: 10.3233/SHTI251149. PMID: 40776166.
Gardemann K, Klausen A, Wulff A et al. Impact of contact isolation in the emergency department: a retrospective cohort study, 30 May 2025, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-6522043/v1]
2024
Knak A., Roheger M., Wulff A. Challenges in Daily Computerised Assessment of Cognitive Functions of Post-COVID Patients, 2024 Aug 22, doi: 10.3233/SHTI240815
Hoogestraat A., Wulff A. A Vision on User-Centered Implementation and Evaluation of Explainable AI for Predicting Hospital-Onset Bacteremia, 2024 Aug 22, doi: 10.3233/SHTI240525
Marschollek M., Marquet M., Reinoso Schiller N., Naim J., Aghdassi S., Behnke M., Ehrenberg S., von Landesberger T., Misailovski M., Prasser F., Scherag A., Schlueter D., Wulff A., RISK PRINCIPE Study Group; Pletz M., Scheithauer S., Automated surveillance and risk prediction with the aim of risk-stratified infection control and prevention (RISK PRINCIPE), 2024 May 16, doi: 10.1007/s00103-100024-03882-w
Das P., Wiese L., Mast M., Böhnke J., Wulff A., Marschollek M., Bode L., Rathert H., Jack T., Schammer S., Beerbaum P., Rübsam N., Karch A., Groszweski-Anders C., Haller A., Frank T., An attention-based bidirectional LSTM-CNN architecture for the early prediction of sepsis, 2024 May 18, doi: 10.1007/s41060-024-00568-z
Archambault D., McGee F., Reinoso-Schiller N., von Landesberger T., Scheithauer S.; Wulff A., Dagstuhl Reports, Volume 14, Issue 2, 3 Overview of Talks, 3.8 Pandemics: A case in point for Big Data, 2024 Jul 30, doi: 10.4230DagRep.14.2
2023
Coldewey C, Klausen A, Otto-Sobotka F, Röhrig R, Lipprandt M. Usability of Automated External Defibrillators: A Randomised, Comparative Simulator Study, International Journal of Human-Computer Interaction,. 2023 Oct 08. doi: 10.1080/10447318.2023.2260973
Bode L, Mast M, Rathert H, Elise Study Group, Jack T, Wulff A. Achieving Interoperable Datasets in Pediatrics: A Data Integration Approach. Stud Health Technol Inform. 2023 Jun 29;305:327-330. doi: 10.3233/SHTI230496. PMID: 37387030.
Biermann P, Infection Control Study Group, Wulff A. An open source solution for smart infection control based on an interoperability standard. Abstract/Software Demonstration. Conference on Medical Informatics Europe 2023. Stockholm, Sweden. 24.05.2023, available at: https://invitepeople.com/public/events/edd1776c4a/seminars/dab7b1dab6
Klausen A, Stanke K, Wulff A. Improving Emergency Service Quality and Patient Safety Through the Use of Cross-Sectoral Digital Feedback Systems - An Overview. Stud Health Technol Inform. 2023 May 2;301:156-161. doi: 10.3233/SHTI230032. PMID: 37172173.
Tute E, Mast M, Wulff A. Targeted Data Quality Analysis for a Clinical Decision Support System for SIRS Detection in Critically Ill Pediatric Patients. Methods Inf Med. 2023 Jun;62(S 01):e1-e9. doi: 10.1055/s-0042-1760238. Epub 2023 Jan 11. PMID: 36630987; PMCID: PMC10306443.
2022
Böhnke J, Rübsamen N, Mast M, Rathert H; ELISE Study Group; Karch A, Jack T, Wulff A. Prediction models for SIRS, sepsis and associated organ dysfunctions in paediatric intensive care: study protocol for a diagnostic test accuracy study. BMJ Paediatr Open. 2022 Oct;6(1):e001618. doi: 10.1136/bmjpo-2022-001618. PMID: 36645795; PMCID: PMC96211
Böhnke J, Varghese J; ELISE Study Group, Karch A, Rübsamen N. Systematic review identifies deficiencies in reporting of diagnostic test accuracy among clinical decision support systems. J Clin Epidemiol. 2022 Aug 17:S0895-4356(22)00191-3. doi: 10.1016/j.jclinepi.2022.08.003. Epub ahead of print. PMID: 35987404.
Bode L, Schamer S, Böhnke J, Elise Study Group, Bott O, Marschollek M, Jack T, Wulff A. Tracing the Progression of Sepsis in Critically Ill Children: Clinical Decision Support for Detection of Hematologic Dysfunction. Appl Clin Inform. 2022 Sep 26. doi: 10.1055/a-1950-9637. Epub ahead of print. PMID: 36162433.
Wulff A, Mast M, Bode L, Rathert H, Jack T; Elise Study Group. Towards an Evolutionary Open Pediatric Intensive Care Dataset in the ELISE Project. Stud Health Technol Inform. 2022 Jun 29;295:100-103. doi: 10.3233/SHTI220670. PMID: 35773816.
Mast M, Marschollek M, Jack T, Wulff A; Elise Study Group. Developing a Data Driven Approach for Early Detection of SIRS in Pediatric Intensive Care Using Automatically Labelled Training Data. Stud Health Technol Inform. 2022 Jan 14;289:228-231. doi: 10.3233/SHTI210901 . PMID: 35062134 .
Wulff A, Biermann P, von Landesberger T, Baumgartl T, Schmidt C, Yussef Alhaji A, Schick K, Waldstein P, Zhu Y, HiGHmed Infection Control Study Group, Krefting D, Scheithauer S, Marschollek M. Tracing COVID-19 infection chains within healthcare institutions - Another brick in the wall against SARS-CoV-2. Stud Health Technol Inform. 2022 Jun 6;290:699-703. doi: 10.3233/SHTI220168. PMID: 35673107
Hamacher K, Kussel T, von Landesberger T, Baumgartl T, Höhn M, Scheithauer S, Marschollek M, Wulff A. Case numbers, re-identification and technical data protection. One aspect of the SARS-CoV-2 pandemic. DuD Data protection and data security. 2022;3:143-8. doi: 10.1007/s11623-022-1579-6
Wulff A, Bode L, Mast M, A knowledge-based, interoperable decision support system for paediatric intensive care medicine. mdi medizin://dokumentation/informatik/informationsmanagement/. 2022;3:85-87. German.
Klausen, Andreas; Klausen, Andrea Diana; Seeger, Insa; Wulff, Antje. Development and evaluation of a descriptive quantitative free text analysis approach for deployment documentation using Visual Basic for Applications. Annual Conference of the German Society for Medical Computing Science, Biometry and Epidemiology e.V. (GMDS) 2022
2021
Tute E, Ganapathy N, Wulff A. A data driven learning approach for the assessment of data quality. BMC Med Inform Decis Mak. 2021 Nov 1;21(1):302. doi: 10.1186/s12911-021-01656-x. PMID: 34724930
Wulff A, Montag S, Rübsamen N, Dziuba F, Marschollek M, Beerbaum P, Karch A, Jack T. Clinical evaluation of an interoperable clinical decision-support system for the detection of systemic inflammatory response syndrome in critically ill children. BMC Med Inform Decis Mak. 2021 Feb 18;21(1):62. doi: 10.1186/s12911-021-01428-7. PubMed PMID: 33602206
Wulff A, Baier C, Ballout S, Tute E, Sommer KK, Kaase M, Sargeant A, Drenkhahn C, Infection Control Study Group, Schlüter D, Marschollek M, Scheithauer S. Transformation of microbiology data into a standardised data representation using OpenEHR. Sci Rep. 2021 May 18;11(1):10556. doi: 10.1038/s41598-021-89796-y PubMed PMID: 34006956
Wulff A, Biermann P, von Landesberger T, Baumgartl T, Schmidt C, Yussef Alhaji A, Schick K, Waldstein P, Zhu Y, HiGHmed Infection Control Study Group, Krefting D, Scheithauer S, Marschollek M. A Smart Infection Control System for COVID-19 Infections in Hospitals. Conference on 66th Annual Meeting of the German Society for Medical Computing Science, Biometry and Epidemiology e. V. (GMDS) 2021(forthcoming)
Seeger, Insa; Klausen, Andreas; Thate, Stefan; Flake, Frank; Peters, Oliver; Rempe, Walter; Peter, Michael; Scheinichen, Frank; Günther, Ulf; Röhrig, Rainer, Community paramedics as an innovative resource in emergency care-first results of an observational study. Emergency+ Rescue Medicine, 2021, 24(3), 194-202. doi:10.1007/s10049-020-00715-6
Klausen, Andreas; Coldewey, Beatrice; Otto-Sobotka, Fabian; Röhrig, Rainer; Lipprandt, Myriam. Usability of Automated External Defibrillators (AED): A randomised, two-arm simulator study (Ease4Life). Conference on 66th Annual Meeting of the German Society for Medical Computing Science, Biometry and Epidemiology e. V. (GMDS) 2021. doi: 10.3205/20gmds205
Seeger, I.; Klausen, A.; Thate, S.; Flake, F.; Peters, O.; Rempe, W.; Peter, M.; Scheinichen, F.; Guenther, U.; Roehrig, R. Community paramedics as an innovative resource in emergency care - first results of an observational study. Emergency + Rescue Medicine 2021,24:194-202 doi: 10.1007/s10049-020-00715-6
2020
Wulff A, Mast M, Hassler M, Montag S, Marschollek M, Jack T. Designing an openEHR-Based Pipeline for Extracting and Standardising Unstructured Clinical Data Using Natural Language Processing. Methods Inf Med. 2020 Dec;59(S 02):e64-e78. doi: 10.1055/s-0040-1716403.
Wulff A, Ballout S, Gietzelt M, Marschollek M, Scheithauer S, and the HiGHmed infection control study group. A Report on Data Modelling for Infection Control in HiGHmed. Conference on Digital ID2020 Digitalisation and Infectious Diseases: Improving patient outcome in the age of big data. doi: 10.13140/RG.2.2.30690.89281
Haarbrandt B, Wulff A, Baier C, Schlüter D, Biermann P, Landesberger T von, et al. With HIS data against COVID-19. E-HEALTH-COM. 2020;5:22-25. german.
Lipprandt, M.; Klausen, A.; Alvarez-Castillo, C.; Bosch, S.; Weyland, A.; Roehrig, R. Systematic failure analysis of critical incidents caused by kinked flow measurement cables from transport ventilators. ANASTHESIOLOGY & INTENSIVE CARE MEDICINE 2020,61:76-84
M. Grau, C. Mathys, M. Zwaan, A. Wißmann, S. Simka, J. Pinn, S. Amin, J. Schnabel, O. Eldergash, B. Schmuck, T. Schütz, A. Klausen, R. Thomas. Mandatory need for X-ray protective goggles in complex vascular interventions Preliminary results of a multicentre, multidisciplinary study. Conference IROS Salzburg 2020
2019
Wulff A*, Montag S*, Marschollek M, Jack T. Clinical Decision-Support Systems for Detection of Systemic Inflammatory Response Syndrome, Sepsis, and Septic Shock in Critically Ill Patients: A Systematic Review. Methods Inf Med. 2019;58(S 02):e43-e57. doi: 10.1055/s-0039-1695717. PubMed PMID: 31499571.
Wulff A, Montag S, Steiner B, Marschollek M, Beerbaum P, Karch A, et al. CADDIE2-evaluation of a clinical decision-support system for early detection of systemic inflammatory response syndrome in paediatric intensive care: Study protocol for a diagnostic study. BMJ Open. 2019;9(6):e028953. doi: 10.1136/bmjopen-2019-028953. PubMed PMID: 31221891.
Wulff A, Sommer KK, Ballout S; HiGHmed Consortium, Haarbrandt B, Gietzelt M. A Report on Archetype Modelling in a Nationwide Data Infrastructure Project. Stud Health Technol Inform. 2019;258:146-150. doi:10.3233/978-1-61499-959-1-146. PubMed PMID: 30942733.
Tute E, Wulff A, Marschollek M, Gietzelt M. Clinical Information Model Based Data Quality Checks: Theory and Example. Stud Health Technol Inform. 2019;258:80-84. doi: doi:10.3233/978-1-61499-959-1-80. PubMed PMID: 30942719.
Bönisch C*, Sargeant A*, Wulff A, Parciak M, Bauer CR, Sax U. FAIRness of openEHR Archetypes and Templates. In: Proceedings of the 12th International SWAT4HCLS Conference: Semantic Web Applications and Tools for Health Care and Life Sciences; 2019 Dec 9-12; Edinburgh, Scotland; provisional proceedings.
Sargeant A, von Landesberger T, Baier C, Bange F, Dalpke A, Eckmanns T, Glöckner S, Kaase M, Krause G, Marschollek M, Malone B, Niepert M, Rey S, Wulff A, Consortium H, Scheithauer S. Early Detection of Infection Chains & Outbreaks: Use Case Infection Control [abstract]. Stud Health Technol Inform. 2019;258:245-246. PMID: 30942759.
Klausen, Andreas; Röhrig, Rainer; Lipprandt, Myriam. Feasibility of Three Head Mounted Eye-Tracker in Anesthesia: A Feasibility Study. Stud Health Technol Inform. 2019,264:1238-1242 doi: 10.3233/SHTI190424 PMID: 31438123
2018
Wulff A, Haarbrandt B, Tute E, Marschollek M, Beerbaum P, Jack T. An interoperable clinical decision-support system for early detection of SIRS in paediatric intensive care using openEHR. Artif Intell Med. 2018;89:10-23. doi:10.1016/j.artmed.2018.04.012 PubMed PMID: 29753616.
Wulff A, Marschollek M. Learning Healthcare Systems in Pediatrics: Cross-Institutional and Data-Driven Decision-Support for Intensive Care Environments (CADDIE). Stud Health Technol Inform. 2018;251:109-12. doi: 10.3233/978-1-61499-880-8-109. PubMed PMID: 29968614.
Wulff A, Haarbrandt B, Marschollek M. Clinical Knowledge Governance Framework for Nationwide Data Infrastructure Projects. Stud Health Technol Inform. 2018;248:196-203. doi: 10.3233/978-1-61499-858-7-196. PubMed PMID: 29726437.
Hechtel N, Wulff A, Marschollek M. Assessment of Decision Models for Hybrid Approaches. Stud Health Technol Inform. 2018;255:180-184. doi: 10.3233/978-1-61499-921-8-180. PubMed PMID: 30306932.
Wulff A, Mast M, Marschollek M. Automated extraction of decision-relevant information from anamnesis reports in paediatric intensive care medicine. Conference on 63rd Annual Meeting of the German Society for Medical Computing Science, Biometry and Epidemiology e. V. (GMDS). doi: 10.3205/18gmds024. German.
Breckner A, Kiss S, Wulff A, Katzensteiner M, Bott OJ. Derivation of openEHR archetypes in the context of rejection diagnostics after kidney transplantation (HAKAN). Conference on 63rd Annual Meeting of the German Society for Medical Computing Science, Biometry and Epidemiology e. V. (GMDS). doi: 10.3205/18gmds177. German.
Haarbrandt B, Wulff A. Open in Europe. E-HEALTH-COM. 2018;5:14-18. German.
Haarbrandt B, Wulff A, Garde S, Boscà D. openEHR and ISO EN 13606 - A comparison. E- HEALTH-COM. 2018;6:2-5. German.
Lins, Christian; Klausen, Andreas; Fudickar, Sebastian J. F.; Hellmers, Sandra; Lipprandt, Myriam; Röhrig, Rainer; Hein, Andreas. Determining Cardiopulmonary Resuscitation Parameters with Differential Evolution Optimisation of Sinusoidal Curves
Lins, Christian; Eckhoff, Daniel; Klausen, Andreas; Hellmers, Sandra; Hein, Andreas; Fudickar, Sebastian. Cardiopulmonary Resuscitation Quality Parameters from Motion Capture Data using Differential Evolution Fitting of Sinusoids. Applied Soft Computing 2019, 79:300-309 doi: 10.1016/j.asoc.2019.03.023
Lins, Christian; Klausen, Andreas; Hellmers, Sandra; Eckhoff, Daniel; Hein, Andreas; Fudickar, Sebastian. Cardiopulmonary Resuscitation Quality Parameters from Inertial Sensor Data using Differential Evolution Fitting of Sinusoids. CoRR
Lins, Christian; Klausen, Andreas; Hellmers, Sandra; Hein, Andreas; Fudickar, Sebastian. Staying Alive-CPR Quality Parameters from Wrist-worn Inertial Sensor Data with Evolutionary Fitted Sinusoidal Models. arXiv 2019 doi: 10.48550/arXiv.1809.07692
2017
Thomas, Rohit Philip; Kowald, Tobias; Schmuck, Bernhard; Eldergash, Osama; Klausen, Andreas; Dikov, Valentin; Easo, Jerry; Chavan, Ajay. Retrospective evaluation of percutaneous access for TEVAR and EVAR: time to make it the standard approach? RöFo 2017,4:347-355 doi:10.1055/s-0043-101387 PMID: 28335059
Wilken, Marc; Hüske-Kraus, Dirk; Klausen, Andreas; Koch, Christian; Schlauch, Wolfgang; Röhrig, Rainer. Alarm fatigue: causes and effects Stud Health Technol and Inform 2017,243:107-111 doi:10.3233/978-1-61499-808-2-107 PMID: 28883181