66 contributions from schools, universities, industry and student laboratories were presented at the DiCE Conference 2025 (Digitalisation in Chemistry Education) on 2 and 3 April. This year's motto is "Opportunities and challenges of AI". Organised by the Universities of Oldenburg, Potdsdam, Constance and Koblenz, we welcomed over 180 participants to the virtual conference. This was preceded by a forum organised by and for young researchers.