RISK-PRINCIPE
RISK-PRINCIPE
Monitoring and risk prediction of nosocomial infections in the interoperable research field
Infections that occur in hospitals (known as nosocomial infections) are a problem for the patients concerned, healthcare staff and society as a whole. Bloodstream infections, in which bacteria enter the bloodstream, are particularly serious. They are among the most serious infections and, despite all medical progress, can lead to long-term damage or even death for those affected.
The containment of such hospital-acquired infections cannot be achieved by introducing medical measures alone (see "Actionable Patient Safety Solutions"). This is why a network of national medical and Computing Science institutions is working with our department to develop automated monitoring of such infections and automated risk prediction. The interdisciplinary research team includes the University Medical Centre Göttingen, Hannover Medical School, Charité in Berlin, the Robert Koch Institute, the Technical University of Munich, the University Hospitals of Jena and Dresden as well as Frankfurt and Heidelberg. The project is also embedded in several similar European and international initiatives.
In the resulting RISK PRINCIPE project, experts in Medical Computing Science, Epidemiology and Infection Medicine will be working closely together until July 2027 to realise this goal in a highly interdisciplinary field.
In order to ensure sufficient reliability of such a system, clinical data will be processed and made available across all locations. Based on this interoperable data set, we will develop a system that helps to better record and visualise bloodstream infections automatically. This will be done taking into account current international developments through the systematic collection of relevant publications.
All of this can lead to better targeted and possibly even new preventive measures that take better account of the risks derived from the data. This not only benefits patients through better care, but also supports healthcare staff.
RISK PRINCIPE closes the gap between individual risk assessment and general infection control measures and thus contributes to the further development of effective AND efficient infection prevention.
Our working group in the RISK-PRINCIPE project
In this project, our department is leading the development of a digital application for embedding the risk prediction of nosocomial infections. Based on a requirements analysis carried out in collaboration with software developers and infectiologists, a system is to be designed that adequately reflects clinical necessities and thus maximises the benefits of such a system. On the one hand, the implemented software should provide medical staff with important information. It will also include visualisations of the infection process and risk analyses, as well as automatic risk detection and prediction using data-based models, which will be developed in separate work packages.
Partner institutions
Partner institutions from the fields of microbiology, infectiology and hospital hygiene:
- University Medical Centre Göttingen, Institute for Hospital Hygiene and Infectiology, Georg-August-University Göttingen
- University Hospital Jena, Institute for Infection Medicine and Hospital Hygiene
- Hannover Medical School, Institute for Medical Microbiology and Hospital Hygiene
- Charité - Universitätsmedizin Berlin, Institute for Hygiene and Environmental Medicine
- University Medicine Ostwestfalen-Lippe, Sustainable Environmental Health Sciences working group
- University Hospital Carl Gustav Carus Dresden, Central Department of Clinical Infectiology
- University Hospital Frankfurt, Medical Clinic 2, Department 16
- Heidelberg University Hospital, Centre for Infectiology, Department of Medical Microbiology and Hygiene
- Technical University of Munich, Institute for Medical Microbiology, Immunology and Hygiene
- Westfälische Wilhelms-Universität Münster, School of Medicine, Institute of Hygiene
- University Hospital Würzburg, Institute for Hygiene and Microbiology
Partner institutions from the field of medical informatics:
- University Hospital Jena, Institute for Medical Statistics, Computing Science and Data Science
- Hannover Medical School, Peter L. Reichertz Institute for Medical Computing Science
- Charité - Universitätsmedizin Berlin, Institute for Health Research at the Charité (BIH), AG Medizininformatik
- University Medicine Ostwestfalen-Lippe, Service Centre Medical Data Science
- Dresden University of Technology, Carl Gustav Carus School of Medicine, Institute for Medical Computing Science and Biometry
- University Hospital Frankfurt, Institute for Medical Informatics
- University Medical Centre Göttingen, Institute for Medical Computing Science, Georg-August-University Göttingen
- Heidelberg University Hospital, Institute for Medical Computing Science
- University of Cologne, Department of Mathematics/Computing Science, Department of Computing Science, Chair of Visualisation and Visual Analytics
- Technical University of Munich, Institute for AI and Computing Science in Medicine
- University Hospital Würzburg, Institute for Clinical Epidemiology and Biometry
Non-university partner institutions:
- Robert Koch Institute (RKI), Department of Infection Epidemiology, Division of Nosocomial Infections, Surveillance of Antibiotic Resistance and Consumption