BRUKER Avance III 500
in operation since 2009
Two sample heads are available for this NMR spectrometer. The BBI sample head is permanently installed.
Sample head BBI: PA BBI 500S2 H-BB-D-05 Z
With Z-gradient
Inverse sample head: ¹H coil inside - X coil outside - Hetero cores are not as sensitive,
but are favourable for ¹H and ¹H detected 2D spectra, therefore
¹H_X-HMQC and -HMBC are more sensitive than on the BBO sample head.

BBO sample head: PA BBO 500S2 BBF-H-D-05 Z
With Z-gradient
Unfortunately, the 2D experiments no longer work with this sample head. Due to its age, it cannot be repaired.
Sample head: ¹H coil outside - XF coil inside → Hetero nuclei are more sensitive than on the BBI sample head.
With ¹H/¹⁹F switchbox

Temperature experiments are possible for both sample heads from -150°C to +150°C. Care must be taken to select a suitable solvent.
For temperature measurements and experiments that are not measured in the automatic system, please make an appointment.
Experiments:
Further experiments on request
| ¹H: | ¹H | |
| ¹H_para | Wide measuring range for paramagnetic cores; small D1 | |
| ¹H D1-120s | → d1 (relaxation time) = 120s | |
| ¹H¹H COSY | H-H correlation within a spin system | |
| ¹H¹H TOCSY | H-H correlation total | |
| ¹H¹H NOESY | H-H correlation due to spatial proximity | |
| NOE diff. | Differential measurement → no automatic | |
| Prohomodec | Homodecoupling → no automatic | |
| 1H jres | Display of couplings in the second dimension → no automatic | |
| ¹H{¹⁹F} | BBO sample head only | |
| ¹H{³¹P} | ||
| ¹H{X} | Decoupling from other heteronuclei is possible | |
| PSYCHE | ¹H{¹H} | |
| DOSY | Diffusion → no automatic | |
| EXSY | Chemical exchange → no automatic | |
| Water suppression | → no automatic | |
| Solvent suppression | → no automatic / for non-deuterated solvents / measurement without lock / with "no-D" shim | |
| ²H | Deuterium | Measurement on the lock channel |
| ⁷Li: | ⁷Li{¹H} | |
| ¹¹B: | ¹¹B | with and without background suppression |
| ¹¹B{¹H} | with and without background suppression | |
| ¹H¹¹B HMQC | ||
| ¹H¹¹B HMBC | ||
| ¹¹B¹¹B COSY | ||
| ¹¹B¹¹B COSY{¹H} | ||
| ¹³C: | ¹³C | |
| ¹³C{¹H} | ||
| ¹³C{¹H} dept135 | CH₃/CH-positive - CH₂-negative | |
| ¹³C{¹H} dept90 | CH-positive | |
| ¹³C{¹H} jmod =apt | CH₃/CH-positive - CH₂/C-negative | |
| ¹H¹³C HMQC | not phase sensitive | |
| ¹H¹³C HSQC | phase sensitive (combination of HMQC and dept135) | |
| ¹H¹³C HMBC | ||
| ¹H¹³C HMBC-et | 1J suppression → no automatic | |
| ¹³C{¹H} inept-rd | Polarisation transfer | |
| ¹³C{¹H} zgig30 | inverse gated - integrable → weekend measurement T1 times must be known | |
| ¹³C Inadequate | No automatic → Weekend measurement | |
| EXSY ¹³C | Chemical exchange → no automatic | |
| ¹³C jres | Display of couplings in the second dimension → no automatic | |
| ¹⁴N | ¹⁴N{¹H} | |
| ¹⁵N: | ¹H¹⁵N HMQC | Coupling constant + measuring range must be specified |
| ¹H¹⁵N HMBC | Coupling constant + measuring range must be specified | |
| ¹⁵N{¹H} inept-rd | Polarisation transfer → Coupling constant + measuring range must be specified | |
| ¹⁵N inept-pnd | Polarisation transfer → Coupling constant + measuring range must be specified | |
| ¹⁵N{¹H} dept135 | only possible if N is present as ¹⁵N isotope | |
| ¹⁵N{¹H} zgig | only possible if N is present as ¹⁵N isotope | |
| ¹⁹F: | Only possible on the BBO sample head | |
| ¹⁹F | ||
| ¹⁹F{¹H} 300ppm | Width of the measuring range = 300 ppm | |
| ¹⁹F{¹H} 150ppm | Width of the measuring range = 150 ppm / centre of the measuring range must be specified | |
| ²⁷Al: | ²⁷Al | with and without background suppression |
| ²⁷Al{¹H} | with and without background suppression | |
| ¹H²⁷Al HMBC | ||
| ²⁹Si: | ²⁹Si | Weekend measurement - switch to inept-pnd if possible |
| ²⁹Si{¹H} gated | inverse gated → 3h measurement time - switch to inept-rd if possible | |
| ²⁹Si{¹H}-inept-rd | Polarisation transfer | |
| ²⁹Si-inept-pnd | Polarisation transfer | |
| ¹H²⁹Si HMQC | ||
| ¹H²⁹Si HMBC | ||
| ²⁹Si Inadequate | No automatic → Weekend measurement | |
| ³¹P: | ³¹P | |
| ³¹P{¹H} | ||
| ³¹P{¹H} gated | inverse gated - integrable → T1 times must be known | |
| ¹H³¹P HMQC | ||
| ¹H³¹P HMBC | ||
| ³⁵Cl: | ³⁵Cl{¹H} | |
| ⁴⁷Ti: | ⁴⁷Ti{¹H} | aring - antiringing sequence |
| ⁷¹Ga: | ⁷¹Ga{¹H} | |
| ⁷⁵As: | ⁷⁵As{¹H} | |
| ⁷⁷Se: | ⁷⁷Se | |
| ⁷⁷Se{¹H} | ||
| ¹H⁷⁷Se HMQC | ||
| ¹H⁷⁷Se HMBC | ||
| ¹¹⁹Sn: | ¹¹⁹Sn{¹H} gated | inverse gated |
| ¹H¹¹⁹Sn HMQC | ||
| ¹H¹¹⁹Sn HMBC | ||
| ¹¹⁹Sn{¹H} inept-rd | Polarisation transfer | |
| ¹¹⁹Sn inept-pnd | Polarisation transfer | |
| ¹²⁵Te: | ¹²⁵Te{¹H} gated | inverse gated |
| ¹H¹²⁵Te HMBC | ||
| ¹²⁵Te{¹H} inept-rd | Polarisation transfer | |
| ¹²⁵Te inept-pnd | Polarisation transfer | |
| ¹⁹⁵Pt | ¹⁹⁵Pt{¹H} | |
| ²⁰⁷Pb: | ²⁰⁷Pb{¹H} | |