The cluster of excellence Hearing4all at the Carl von Ossietzky University Oldenburg is seeking to fill the position of a
full-time position (part-time possible), TVL E13 for 3 years
in the Neurogenetics Division of Prof. Nothwang, Department of Neuroscience, School of Medicine and Health Science.
Age related hearing loss (ARHL) is the most common health condition affecting one third of the population over age 65. Loss of spiral ganglion neurons (SGN), conveying sound information from the hair cells in the cochlea to the central auditory system, is a major contributor to ARHL. In mammals, three types of auditory nerve fibers can be distinguished based upon their physiological properties.
Due to sound sensitivity at low frequencies similar to humans, the Mongolian gerbil has become a well-established model organism to study age-related hearing loss.
In this project we are aiming for the molecular characterization of the gerbil SGN subpopulations along the tonotopic axis of the cochlea as well as their distribution during aging using molecular in situ analyses and next generation sequencing approaches.
Insights into molecular changes in SGNs during aging might lead to better understanding of their age dependent decline and help to develop new therapeutic approaches.
We seek a highly motivated candidate with
- an academic university degree (Master or equivalent) in biology or related fields
- ability to perform independent research, indicated by a high quality PhD and a good publication record
- profound knowledge in Neuroscience
- advanced experience in expression studies (qRT-PCR, RNA in situ hybridization and immunohistochemical analyses)
- ideally experience with analysis of RNA-Seq data
- experience with single cell isolation (FACS, patch-clamp, laser microdissection) are of advantage
- experience with handling laboratory animals are of advantage
- ability to work independently, thoroughly and as a team player in a dynamic group
We offer an attractive work environment with excellent facilities (STED and confocal microscopy, Axioscan microscope, patch-clamp set-up, real time PCR, animal facility). The project is embedded in the cluster of excellence Hearing4all (http://hearing4all.eu/EN/), an interdisciplinary cluster jointly run by the University of Oldenburg, Hannover Medical School and Leibniz University Hannover.
The University of Oldenburg is dedicated to increasing the percentage of female employees in the field of science. Therefore, female candidates are strongly encouraged to apply. In accordance to § 21 Section 3 NHG, female candidates with equal qualifications will be preferentially considered. Applicants with disabilities will be given preference in case of equal qualification.
Please submit your motivation letter, CV, certificates and name of two references (preferably via E-Mail as a single PDF-file) until 29th March 2019 to:
Dr. Lena Ebbers; email@example.com; Abt. Neurogenetik, Carl von Ossietzky Universität Oldenburg, Carl von Ossietzky Str. 9-11, D-26129 Oldenburg.