Leitung

Prof. Dr. Sven Doye

W3 1-203, Carl-von-Ossietzky-Str. 9 - 11 (» Adresse und Lageplan)

Immer, wenn ich im Büro bin.

+49 441 798-3888  (F&P

Sekretariat

Gisela Kaulfuß

Institut für Chemie  (» Postanschrift)

W03 2-279 (» Adresse und Lageplan)

Mo - Fr. 10:00 - 11:30 Uhr und n. V.

+49 441 798-3716  (F&P

Publikationen

92.
Dennis Geik, Alina Büker, Felix Fornfeist, Marc Schmidtmann, Sven Doye
"Catalytic C–H Functionalization of Trimethylamine"
Synlett 2024, 35, 957-962. Special Issue "Chemical Synthesis and Catalysis in Germany"

91.
Hermann Thye,+ Felix Fornfeist,+ Dennis Geik, Levi L. Schlüschen, Marc Schmidtmann, Sven Doye
"Titanium-Catalyzed Intermolecular Hydroaminoalkylation of Terminal Alkynes"
Synthesis 2023, 55, 3759-3776.
+ These authors contributed equally to this work.

90.
Niklas Thoben, Tobias Kaper, Simon de Graaff, Luca Gerhards, Marc Schmidtmann, Thorsten Klüner, Rüdiger Beckhaus, Sven Doye
"Density Functional Theory Calculations for Multiple Conformers Explaining the Regio- and Stereoselectivity of Ti-Catalyzed Hydroaminoalkylation Reactions"
ChemPhysChem. 2023, 24, e202300370.

89.
Tobias Kaper, Aylişa Elma, Hermann Thye, Paula Knupe-Wolfgang, René Zimmering, Marc Schmidtmann, Sven Doye
"Titanium-Catalyzed Intermolecular Hydroaminoalkylation of Allenes and Methylenecyclopropanes"
Eur. J. Org. Chem. 2022, e202200991.

88.
Tobias Kaper,+ Dennis Geik,+ Felix Fornfeist, Marc Schmidtmann, Sven Doye
"Stereoselective Synthesis of Tertiary Allylic Amines by Titanium-Catalyzed Hydroaminoalkylation of Alkynes with Tertiary Amines"
Chem. Eur. J. 2022, 28, e202103931.
+ These authors contributed equally to this work.

87.
Dennis Geik, Michael Rosien, Jens Bielefeld, Marc Schmidtmann, Sven Doye
"Titanium-Catalyzed Intermolecular Hydroaminoalkylation of Alkenes with Tertiary Amines"
Angew. Chem. Int. Ed. 2021, 60, 9936-9940; Angew. Chem. 2021, 133, 10024-10028.

86.
Tobias Kaper, Malte Fischer, Hermann Thye, Dennis Geik, Marc Schmidtmann, Rüdiger Beckhaus, Sven Doye
"Intermolecular Hydroaminoalkylation of Alkynes"
Chem. Eur. J. 2021, 27, 6899-6903.

85.
Michael Warsitz, Stefan H. Rohjans, Marc Schmidtmann, Sven Doye
"Hydroaminoalkylation/Buchwald-Hartwig Amination Sequences for the Synthesis of Novel Thieno- or Benzothieno-Annulated Tetrahydropyridines, Tetrahydroazasilines, and Tetrahydroazasilepines"
Eur. J. Org. Chem. 2021, 830-849.

84.
Michael Warsitz, Sven Doye
"Two-Step Procedure for the Synthesis of 1,2,3,4-Tetrahydroquinolines"
Eur. J. Org. Chem. 2020, 6997-7014.

83.
Michael Warsitz, Sven Doye
"Linear Hydroaminoalkylation Products from Alkyl-Substituted Alkenes"
Chem. Eur. J. 2020, 26, 15121-15125.

82.
Tobias Kaper, Malte Fischer, Michael Warsitz, René Zimmering, Rüdiger Beckhaus, Sven Doye
"Intermolecular Hydroaminoalkylation of Propadiene"
Chem. Eur. J. 2020, 26, 14300-14304.

81.
Jens Bielefeld, Sven Doye
"Fast Titanium-Catalzed Hydroaminomethylation of Alkenes and the Formal Conversion of Methylamine"
Angew. Chem. Int. Ed. 2020, 59, 6138-6143; Angew. Chem. 2020, 132, 6194-6199.

80.
Michael Rosien, Iris Töben, Marc Schmidtmann, Rüdiger Beckhaus, Sven Doye
"Titanium-Catalyzed Hydroaminoalkylation of Ethylene"
Chem. Eur. J. 2020, 26, 2138-2142.

79.
Jens Bielefeld, Ekaterina Kurochkina, Marc Schmidtmann, Sven Doye
"New Titanium Complexes and Their Use in Hydroamination and Hydroaminoalkylation Reactions"
Eur. J. Inorg. Chem. 2019, 3713-3718.

78.
Tobias Kaper, Sven Doye
"Hydroaminoalkylation/Buchwald-Hartwig amination sequences for the synthesis of benzo-annulated seven-membered nitrogen heterocycles"
Tetrahedron 2019, 75, 4343-4350.

77.
Jens Bielefeld, Steffen Mannhaupt, Marc Schmidtmann, Sven Doye
"Hydroaminoalkylation of Allenes"
Synlett 2019, 30, 967-971.

76.
Stefan H. Rohjans, Jan H. Ross, Lars H. Lühning, Lukas Sklorz, Marc Schmidtmann, Sven Doye
"Titanium Catalysts with Linked Indenyl–Amido Ligands for Hydroamination and Hydroaminoalkylation Reactions"
Organometallics 2018, 37, 4350-4357.

75.
Luisa Stelter, Thomas Teusch, Jens Bielefeld, Sven Doye, Thorsten Klüner 
"Theoretical Studies on the Hydroaminoalkylation of Alkenes with Primary and Secondary Amines"
Chem. Eur. J. 2018, 24, 12485-12489.

74.
Jens Bielefeld, Sven Doye
"Dimethylamine as a Substrate in Hydroaminoalkylation Reactions"
Angew. Chem. Int. Ed. 2017, 56, 15155-15158; Angew. Chem. 2017, 129, 15352-15355.

73.
Lars H. Lühning, Michael Rosien, Sven Doye
"Thieme Chemistry Journals Awardees – Where Are They Now? Titanium-Catalyzed Hydroaminoalkylation of Vinylsilanes and a One-Pot Procedure for the Synthesis of 1,4-Benzoazasilines"
Synlett 2017, 28, 2489-2494.

72.
Lars H. Lühning, Julia Strehl, Marc Schmidtmann, Sven Doye
"Hydroaminoalkylation of Allylsilanes and a One-Pot Procedure for the Synthesis of 1,5-Benzoazasilepines"
Chem. Eur. J. 2017, 23, 4197-4202.

71.
Marco Weers, Lars H. Lühning, Vanessa Lührs, Christian Brahms, Sven Doye
"One-Pot Procedure for the Synthesis of 1,5-Benzodiazepines from N-Allyl-2-bromoanilines"
Chem. Eur. J. 2017, 23, 1237-1240.

70.
Lars H. Lühning, Christian Brahms, Jelte P. Nimoth, Marc Schmidtmann, Sven Doye
"A New N-Trityl-Substituted Aminopyridinato Titanium Catalyst for Hydroamination and Hydroaminoalkylation Reactions − Unexpected Intramolecular C−H Bond Activation"
 Z. Anorg. Allg. Chem. 2015, 641, 2071-2082.

69.
Jaika Dörfler, Besnik Bytyqi, Sascha Hüller, Nicola M. Mann, Christian Brahms, Marc Schmidtmann, Sven Doye
"An Aminopyridinato Titanium Catalyst for the Intramolecular Hydroaminoalkylation of Secondary Aminoalkenes"
Adv. Synth. Catal. 2015, 357, 2265-2276.

68.
Manfred Manßen, Nicolai Lauterbach, Jaika Dörfler, Marc Schmidtmann, Wolfgang Saak, Sven Doye, Rüdiger Beckhaus
"Efficient Access to Titanaaziridines by C–H Activation of N-Methylanilines at Ambient Temperature"
Angew. Chem. Int. Ed. 2015, 54, 4383-4387; Angew. Chem. 2015, 127, 4458-4462.

67.
Jaika Dörfler, Till Preuß, Christian Brahms, Dennis Scheuer, Sven Doye
"Intermolecular hydroaminoalkylation of alkenes and dienes using a titanium mono(formamidinate) catalyst"
Dalton Trans. 2015, 44, 12149-12168.

66.
Jan H. Ross, Stefan H. Rohjans, Marc Schmidtmann, Sven Doye
"Highly flexible synthesis of indenylethylamines as ligand precursors for titanium complexes"
ARKIVOC 2015, (ii), 76-92.

65.
Jaika Dörfler, Till Preuß, Alexandra Schischko, Marc Schmidtmann, Sven Doye
"A 2,6-Bis(phenylamino)pyridinato Titanium Catalyst for the Highly Regioselective Hydroaminoalkylation of Styrenes and 1,3-Butadienes"
Angew. Chem. Int. Ed. 2014, 53, 7918-7922; Angew. Chem. 2014, 126, 8052-8056.

64.
Jaika Dörfler, Sven Doye
"A Commercially Available Tantalum Catalyst for the Highly Regioselective Intermolecular Hydroaminoalkylation of Styrenes"
Eur. J. Org. Chem. 2014, 2790-2797.

63.
Jan H. Ross, Till Preuß, Christian Brahms, Sven Doye
"A Practical and Inexpensive One-Pot Synthesis of Bis(indenyl)dimethyltitanium with Aqueous Workup Procedure"
Z. Anorg. Allg. Chem. 2014, 640, 118-121.

62.
Christian Brahms, Patrik Tholen, Wolfgang Saak, Sven Doye
"An (Aminopyrimidinato)titanium Catalyst for the Hydroamination of Alkynes and Alkenes"
Eur. J. Org. Chem. 2013, 7583-7592.

61.
Till Preuß, Wolfgang Saak, Sven Doye
"Titanium-Catalyzed Intermolecular Hydroaminoalkylation of Conjugated Dienes"
Chem. Eur. J. 2013, 19, 3833-3837.

60.
Jaika Dörfler, Sven Doye
"Aminopyridinato Titanium Catalysts for the Hydroaminoalkylation of Alkenes and Styrenes"
Angew. Chem. Int. Ed. 2013, 52, 1806-1809; Angew. Chem. 2013, 125, 1851-1854.

59.
Daniel Jaspers, Wolfgang Saak, Sven Doye
"Dinuclear Titanium Complexes with Sulfamide Ligands as Precatalysts for Hydroaminoalkylation and Hydroamination Reactions"
Synlett 2012, 23, 2098-2102.

58.
Karolin Mellentin-Born, Wolfgang Saak, Sven Doye
"Crystal structure of bis(dimethylamido)-bis(ethyl-3-(pentafluorophenylamido)but-2-enoate)titanium, C28H30F10N4O4Ti" 
Z. Kristallogr. NCS 2012, 227, 387-388.

57.
Sven Doye
"Eine intermolekulare Ritter-Reaktion an Alkanen" (Treffpunkt Forschung)
Chem. unserer Zeit 2012, 46, 137.

56.
Karolin Born, Sven Doye
"Zirconium-Catalyzed Intermolecular Hydroamination of Alkynes with Primary Amines"
Eur. J. Org. Chem. 2012, 764-771.

55.
Insa Prochnow, Patrick Zark, Thomas Müller, Sven Doye
"The Mechanism of the Titanium-Catalyzed Hydroaminoalkylation of Alkenes"
Angew. Chem. Int. Ed. 2011, 50, 6401-6405; Angew. Chem. 2011, 123, 6525-6529.

54.
Daniel Jaspers, Sven Doye 
"Potassium Hydroxide Catalyzed Addition of Arylamines to Styrenes"
Synlett 2011, 1444-1448.

53.
Sven Doye 
"Pd-katalysierte Synthese von Heterocyclen: Die Macht der Liganden" (Treffpunkt Forschung)
Chem. unserer Zeit 2011, 45, 80.

52.
Sven Doye 
"Semistabile Triphenylphosphonium-Ylide: Hoch stereoselektive Wittig-analoge Olefinierungsreaktion" (Treffpunkt Forschung)
Chem. unserer Zeit 2010, 44, 169.

51.
René Severin, Jessica Reimer, Sven Doye 
"One-Pot Procedure for the Synthesis of Unsymmetrical Diarylalkynes"
J. Org. Chem. 2010, 75, 3518-3521.

50.
Daniel Jaspers, Raphael Kubiak, Sven Doye 
"Recyclable Gallium as Catalyst Precursor for a Convenient and Solvent-Free Method for the Intermolecular Addition of Sulfonamides to Alkenes"
Synlett 2010, 1268-1272.

49.
Thomas Janssen, René Severin, Mira Diekmann, Marion Friedemann, Detlev Haase, Wolfgang Saak, Sven Doye, Rüdiger Beckhaus
"Bis(h5:h1-pentafulvene)titanium Complexes: Catalysts for Intramolecular Alkene Hydroamination and Reagents for Selective Reactions with N-H Acidic Substrates"
Organometallics 2010, 29, 1806-1817.

48.
Raphael Kubiak, Insa Prochnow, Sven Doye 
"[Ind2TiMe2]: A Catalyst for the Hydroaminomethylation of Alkenes and Styrenes"
Angew. Chem. Int. Ed. 2010, 49, 2626-2629; Angew. Chem. 2010, 122, 2683-2686.

47.
René Severin, Jessica Reimer, Sven Doye 
"One-Pot Synthesis of Fluorinated 1-Benzoyl-3,4-dihydroisoquinolines from [2-(o-Alkynylphenyl)ethyl]amines by a Hydroamination/Oxidation Sequence"
Eur. J. Org. Chem. 2010, 51-54.

46.
Kerstin Gräbe, Björn Zwafelink, Sven Doye
"One-Pot Procedure for the Synthesis of N-Substituted 2-(Arylmethyl)pyrrolidines from 1-Aryl-2-cyclopropylalkynes and Primary Amines by a Hydroamination/Cyclopropylimine Rearrangement/Reduction-Sequence"
Eur. J. Org. Chem. 2009, 5565-5575.

45.
Insa Prochnow, Raphael Kubiak, Okko N. Frey, Rüdiger Beckhaus, Sven Doye 
"Tetrabenzyltitanium: An Improved Catalyst for the Activation of sp3 C-H Bonds Adjacent to Nitrogen Atoms"
ChemCatChem 2009, 1, 162-172.

44.
Stefan Mark, Nikola Gaidzik, Sven Doye, Markus Enders
"Organochromium complexes as catalysts for the carboalumination of unactivated terminal olefins"
Dalton Trans. 2009, 4875-4877.

43.
Katharina Weitershaus, Benjamin D. Ward, Raphael Kubiak, Carsten Müller, Hubert Wadepohl, Sven Doye, Lutz H. Gade 
"Titanium hydroamination catalysts bearing a 2-aminopyrrolinato spectator ligand: monitoring the individual reaction steps"
Dalton Trans. 2009, 4586-4602.

42.
Raphael Kubiak, Insa Prochnow, Sven Doye
"Titanium-Catalyzed Hydroaminoalkylation of Alkenes by C-H Bond Activation at sp3 Centers in the α-Position to a Nitrogen Atom"
Angew. Chem. Int. Ed. 2009, 48, 1153-1156; Angew. Chem. 2009, 121, 1173-1176.

41.
Sven Doye
"Hydroamination"
Science of Synthesis, Vol. 40a, Georg Thieme Verlag KG, Stuttgart, 2009, 241-304.

40.
Carsten Müller, Rainer Koch, Sven Doye
"Mechanism of the Intramolecular Hydroamination of Alkenes Catalyzed by Neutral Indenyltitanium Complexes: A DFT Study"
Chem. Eur. J. 2008, 14, 10430-10436.

39.
Kerstin Gräbe, Frauke Pohlki, Sven Doye
"Neutral Ti Complexes as Catalysts for the Hydroamination of Alkynes and Alkenes: Do the Labile Ligands Change the Catalytic Activity?"
Eur. J. Org. Chem. 2008, 4815-4823.

38.
Carsten Müller, Wolfgang Saak, Sven Doye
"Neutral Group-IV Metal Catalysts for the Intramolecular Hydroamination of Alkenes"
Eur. J. Org. Chem. 2008, 2731-2739.

37.
René Severin, Didin Mujahidin, Jessica Reimer, Sven Doye
"Synthesis of Benzylisoquinoline Derivatives Possessing Electron-Withdrawing Substituents on the Benzene Ring of the Isoquinoline Skeleton"
Heterocycles 2007, 74, 683-700. 

36.
Klaudia Marcseková, Christian Loos, Frank Rominger, Sven Doye
"Titanium and Zirconium Complexes with Helical Bis(phenolato) Ligands as Hydroamination Catalysts"
Synlett 2007, 2564-2568. 

35.
René Severin, Sven Doye
"The Catalytic Hydroamination of Alkynes"
Chem. Soc. Rev. 2007, 36, 1407-1420.

34.
Sven Doye
"Asymmetrische Multikomponenten-Domino-Reaktion" (Treffpunkt Forschung)
Chem. unserer Zeit 2007, 41, 78-79.

33.
Klaudia Marcseková, Sven Doye
"HI-Catalyzed Hydroamination and Hydroarylation of Alkenes"
Synthesis 2007, 145-154.

32.
Carsten Müller, Christian Loos, Nikola Schulenberg, Sven Doye
"Neutral Ti Catalysts for the Intramolecular Hydroamination of Alkenes"
Eur. J. Org. Chem. 2006, 2499-2503. 

31.
Klaudia Markseková, Bernd Wegener, Sven Doye
"Ind2TiMe2-Catalyzed Addition of Methyl- and Ethylamines to Alkynes"
Eur. J. Org. Chem. 2005, 4843-4851.

30.
Didin Mujahidin, Sven Doye
"Enantioselective Synthesis of (+)-(S)-Laudanosine and (–)-(S)-Xylopinine"
Eur. J. Org. Chem. 2005, 2689-2693.

29.
Andreas Heutling, Frauke Pohlki, Igor Bytschkov, Sven Doye
"Hydroamination/Hydrosilylation Sequence Catalyzed by Titanium Complexes"
Angew. Chem. Int. Ed. 2005, 44, 2951-2954; Angew. Chem. 2005, 117, 3011-3013.

28.
Andreas Heutling, René Severin, Sven Doye
"Regioselective Preparation of 2-Phenylethylamins from 1-Phenyl-2-alkyl-alkynes by Hydroamination/Reduction Sequences"
Synthesis, 2005, 1200-1204.

27.
Sven Doye
"Development of the Ti-Catalyzed Intermolecular Hydroamination of Alkynes"
Synlett 2004, 1653-1672.

26.
Andreas Heutling, Frauke Pohlki, Sven Doye
"[Ind2TiMe2]: A General Catalyst for the Intermolecular Hydroamination of Alkynes"
Chem. Eur. J. 2004, 10, 3059-3071.

25.
Frauke Pohlki, Igor Bytschkov, Holger Siebeneicher, Andreas Heutling, Wilfried A. König, Sven Doye
"Enantiomerically Pure Amines as Substrates for the Ti-Catalyzed Hydroamination of Alkynes"
Eur. J. Org. Chem. 2004, 1967-1972.

24.
Holger Siebeneicher, Igor Bytschkov, Sven Doye
"A flexible and Catalytic One-Pot Procedure for the Synthesis of Indoles"
Angew. Chem. Int. Ed. 2003, 42, 3042-3044; Angew. Chem. 2003, 115, 3151-3153.

23.
Igor Bytschkov, Holger Siebeneicher, Sven Doye
"A Flexible Synthesis of Indoline, Indolizidine and Pyrrolizidine Derivatives"
Eur. J. Org. Chem. 2003, 2888-2902.

22.
Igor Bytschkov, Sven Doye
"Group-IV Metal Complexes as Hydroamination Catalysts"
Eur. J. Org. Chem. 2003, 935-946.

21.
Frauke Pohlki, Sven Doye
"The catalytic hydroamination of alkynes"
Chem. Soc. Rev. 2003, 32, 104-114.

20.
Igor Bytschkov, Sven Doye
"The Cp2TiMe2-catalyzed intramolecular hydroamination/cyclization of aminoalkynes"
Tetrahedron. Lett. 2002, 43, 3715-3718.

19.
Frauke Pohlki, Andreas Heutling, Igor Bytschkov, Torsten Hotopp, Sven Doye
"Titanium Complexes as Catalysts for the Intermolecular Hydroamination of Alkynes"
Synlett 2002, 799-801.

18.
Andreas Heutling, Sven Doye
"Cp*2TiMe2: An Improved Catalyst for the Intermolecular Addition of n-Alkyl- and Benzylamines to Alkynes"
J. Org. Chem. 2002, 67, 1961-1964.

17.
Holger Siebeneicher, Sven Doye
"Highly Flexible Synthesis of 2-Arylethylamine Derivatives"
Eur. J. Org. Chem. 2002, 1213-1220.

16.
Edgar Haak, Igor Bytschkov, Sven Doye
"A One-Pot Procedure for the Synthesis of α-Amino Phosphonates from Alkynes"
Eur. J. Org. Chem. 2002, 457-463.

15.
Igor Bytschkov, Sven Doye
"Microwave Assisted Catalytic Intermolecular Hydroamination of Alkynes"
Eur. J. Org. Chem. 2001, 4411-4418.

14.
Sven Doye
"Catalytic C-H Activation of sp3 C-H Bonds in α-Position to a Nitrogen Atom – Two New Approaches" (Highlight)
Angew. Chem. Int. Ed. 2001, 40, 3351-3353; Angew. Chem. 2001, 113, 3455-3457.

13.
Sven Doye
"Eine Alternative zur Aldolreaktion" (Treffpunkt Forschung)
Chem. unserer Zeit 2001, 35, 126-127.

12.
Frauke Pohlki, Sven Doye
"The Mechanism of the [Cp2TiMe2]-Catalyzed Intermolecular Hydroamination of Alkynes"
Angew. Chem. Int. Ed. 2001, 40, 2305-2308; Angew. Chem. 2001, 113, 2361-2364. 

11.
Sven Doye
"Prolin katalysiert auch intermolekulare Aldolreaktionen" (Treffpunkt Forschung)
Chem. unserer Zeit 2001, 35, 62-63.

10.
Edgar Haak, Holger Siebeneicher, Sven Doye
"An Ammonia Equivalent for the Dimethyltitanocene-Catalyzed Intermolecular Hydroamination of Alkynes"
Org. Lett. 2000, 2, 1935-1937. 

9.
Holger Siebeneicher, Sven Doye
"Dimethyltitanocene Cp2TiMe2: A Useful Reagent for C-C and C-N Bond Formation"
J. Prakt. Chem. 2000, 342, 102-106. 

8.
Edgar Haak, Igor Bytschkov, Sven Doye
"Intermolecular Hydroamination of Alkynes Catalyzed by Dimethyltitanocene"
Angew. Chem. Int. Ed. 1999, 38, 3389-3391; Angew. Chem. 1999, 111, 3584-3586. 

7.
Edgar Haak, Sven Doye
"Katalytische Hydroaminierung von Alkenen und Alkinen"
Chem. unserer Zeit 1999, 33, 296-303. 

6.
Timo Flessner, Sven Doye
"N,N´-Bis(3,5-Di-t-butylsalicylidene)-1,2-cyclohexane-diamino-manganese(III)chloride - the Jacobsen Catalyst"
J. Prakt. Chem. 1999, 341, 436-444. 

5.
Timo Flessner, Sven Doye
"Cesium Carbonate: A Powerful Inorganic Base in Organic Synthesis"
J. Prakt. Chem. 1999, 341, 186-190.

4.
Rudolf Wartchow, Sven Doye
"Synthesis and characterization of rac-[ethylene-1,2-bis-(h5-4,5,6,7-tetrahydro-1-indenyl)]zirconium bisamides (EBTHI)Zr(NHR)2"
J. Organomet. Chem. 1998, 566, 287-291.

3.
Sven Doye, Torsten Hotopp, Rudolf Wartchow, Ekkehard Winterfeldt
"The Enantioselective Total Synthesis of (–)-Myltaylenol"
Chem. Eur. J. 1998, 4, 1480-1488.

2.
Jean-François Marcoux, Sven Doye, Stephen L. Buchwald
"A General Copper-Catalyzed Synthesis of Diaryl Ethers"
J. Am. Chem. Soc. 1997, 119, 10539-10540.

1.
Sven Doye, Torsten Hotopp, Ekkehard Winterfeldt
"The enantioselective total synthesis of ( –)-myltaylenol"
J. Chem. Soc., Chem. Commun. 1997, 1491-1492.

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