Dr. Rabea Bartölke
Kontakt
Dr. Rabea Bartölke
AG Neurosensorik/Animal Navigation, IBU
Carl von Ossietzky Universität Oldenburg
Carl-von-Ossietzky-Straße 9-11
26129 Oldenburg
Telefon: +49 (0)441 798 3272
E-Mail: rabea.bartoelke[at]uol.de
Dr. Rabea Bartölke
Wissenschaftlicher Werdegang
2019 – present: Postdoctoral researcher, Institute of Biology and Environmental Sciences, University of Oldenburg, Germany, AG Animal Navigation/Neurosensorik (Group leader: Prof. Dr. H. Mouritsen)
2016 – 2019: Postdoctoral researcher at the Cancer Research Centre of Toulouse (CRCT), France, Team “Cholesterol Metabolism and Therapeutic Innovations” (Group leaders: Dr. M. Poirot, Dr. S. Silvente-Poirot)
Studium
2010 – 2015: Ph.D. “Disaccharide Transport Across Animal Membranes“; University of Osnabrueck, Germany, Division of Animal Physiology (Group leader: Prof. Dr. H. Wieczorek)
2010: Master of Sciences (M.Sc.) Cell Biology, University of Osnabrueck
2009: Master Thesis “Investigation of candidate binding partners for the human vacuolar H+-ATPase C subunit” at the Cambridge Institute for Medical Research, Cambridge University, UK, Division of Medical Genetics (Group leader: Prof. Dr. F. Karet)
2007: Bachelor of Sciences (B.Sc.) Cell Biology, University of Osnabrueck
Wissenschaftliche Veröffentlichungen
Preprints
Bartoelke R, Niessner C, Reinhard K, Wolfrum U, Meimann S, Bolte P, Feederle R, Mouritsen H, Dedek K, Peichl, Winklhofer M. 2024. Full-length Cryptochrome 1 in the outer segments of the retinal blue cone photoreceptors in humans and great apes suggests a role beyond transcriptional repression, bioRxiv: 2024.10.10.617617. https://doi.org/10.1101/2024.10.10.617617
Hanić M, Antill LM, Gehrckens AS, Schmidt J, Görtemaker K, Bartölke R, El-Baba TJ, Xu J, Koch KW, Mouritsen H, Benesch JLP, Hore PJ, Solov’yov IA. Dimerisation of European robin cryptochrome 4a. bioRxiv 2023.04.11.536350; doi.org/10.1101/2023.04.11.536350.
2024
Yee C*, Bartölke R*, Görtemaker K, Schmidt J, Leberecht B, Mouritsen H, Koch KW. Comparison of retinol binding protein 1 with cone specific G-protein as putative effector molecules in cryptochrome signalling. Sci Rep. 2024 Nov 16;14(1):28326. https://doi.org/10.1038/s41598-024-79699-z
2023
Golesworthy MJ, Zollitsch T, Luo J, Selby D, Jarocha LE, Henbest KB, Paré-Labrosse O, Bartölke R, Schmidt J, Xu J, Mouritsen H, Hore PJ, Timmel CR, Mackenzie SR. Singlet-triplet dephasing in radical pairs in avian cryptochromes leads to time-dependent magnetic field effects. J Chem Phys. 2023 Sep 14;159(10):105102. http://doi.org/10.1063/5.0166675
Hanić M, Antill LM, Gehrckens AS, Schmidt J, Görtemaker K, Bartölke R, El-Baba TJ, Xu J, Koch KW, Mouritsen H, Benesch JLP, Hore PJ, Solov'yov IA. Dimerization of European Robin Cryptochrome 4a. J Phys Chem B. 2023;127(28):6251-6264. doi.org/10.1021/acs.jpcb.3c01305
Timmer D, Frederiksen A, Lünemann DC, Thomas AR, Xu J, Bartölke R, Schmidt J, Kubař T, De Sio A, Solov'yov IA, Mouritsen H, Lienau C. Tracking the Electron Transfer Cascade in European Robin Cryptochrome 4 Mutants. J Am Chem Soc. 2023 May 31;145(21):11566-11578. doi.org/10.1021/jacs.3c00442.
2022
Görtemaker, K.*, Yee, C.*, Bartölke, R.*, Behrmann, H., Voss, J. O., Schmidt, J., Xu, J., Solovyeva, V., Leberecht, B., Behrmann, E., Mouritsen, H., & Koch, K. W. (2022). Direct Interaction of Avian Cryptochrome 4 with a Cone Specific G-Protein. Cells, 11(13).
Einwich, A., Seth, P. K., Bartölke, R., Bolte, P., Feederle, R., Dedek, K., & Mouritsen, H. (2022). Localisation of cryptochrome 2 in the avian retina. J Comp Physiol A Neuroethol Sens Neural Behav Physiol, 208(1), 69-81.
2021
Lünemann DC, Thomas AR, Xu J, Bartölke R, Mouritsen H, De Sio A, Lienau C (2021) Distinguishing between coherent and incoherent signals in excitation-emission spectroscopy. Opt Express 29:24326–24337.
Bartölke R, Behrmann H, Görtemaker K, Yee C, Xu J, Behrmann E, Koch K (2021) The secrets of cryptochromes: photoreceptors, clock proteins, and magnetic sensors. Neuroforum 27:151-157.
Xu J, Jarocha LE, Zollitsch T, Konowalczyk M, Henbest KB, Richert S, Golesworthy MJ, Schmidt J, Déjean V, Sowood DJC, Bassetto M, Luo J, Walton JR, Fleming J, Wei Y, Pitcher TL, Moise G, Herrmann M, Yin H, Wu H, Bartölke R, Käsehagen SJ, Horst S, Dautaj G, Murton PDF, Gehrckens AS, Chelliah Y, Takahashi JS, Koch KW, Weber S, Solov'yov IA, Xie C, Mackenzie SR, Timmel CR, Mouritsen H, Hore PJ. Magnetic sensitivity of cryptochrome 4 from a migratory songbird. Nature. 2021 Jun;594(7864):535-540. doi.org/10.1038/s41586-021-03618-9.
before 2020
Vitavska, O. Bartölke, R., Tabke, K. Heinisch, J.J. Wieczorek, H. 2018. Interaction of mammalian and plant H+/sucrose transporters with 14-3-3 proteins. Biochemical Journal, 20180293
Bartölke, R. Heinisch, J.J. Wieczorek, H. Vitavska, O. 2014. Proton-associated transport of mammalian solute carrier family 45: an analysis in Saccharomyces cerevisiae. Biochemical Journal, 464(2): 193-201
*These authors contributed equally.
Conference Contributions
2023: Gortemaker, K.*, Yee, C.*, Bartolke, R.*, Behrmann, H., Voss, J. O., Schmidt, J., Xu, J., Solovyeva, V., Leberecht, B., Behrmann, E., Mouritsen, H., & Koch, K. W. (2022). Direct Interaction of Avian Cryptochrome 4 with a Cone Specific G-Protein. 11th RIN Conference on Animal Navigation, London, UK, 12.-14.4.2023
Xu, J. et al. ; Görtemaker, K. et al. Cryptochromes as primary magnetic sensors in migratory birds (S31-1). 15th Göttingen Meeting of the German Neuroscience Society, Göttingen, Germany, 22.-24.3.2023
2018: Bartölke, R. Silvente-Poirot, S. Poirot, M. Cholesterol metabolism and cancer: Toward new perspectives in breast cancer treatment. Europhysiology 2018, London, UK, 14.-16.9.2018
2013: Bartölke, R. Wieczorek, H. Vitavska, O. The mammalian solute carrier family 45 of alternative sugar transporters, Göttinger Transporttage, Göttingen, Germany, 23.-24.11. 2013
2013: Bartölke, R. Wieczorek, H. Vitavska, O. The mammalian solute carrier family 45 of alternative sugar transporters, Annual Meeting of the German Physiological Society, Heidelberg, Germany, Abstract O84, 2.-5.3.2013
2012: Bartölke, R. Wieczorek, H. Vitavska, O. Mammalian sucrose transporters. Physiology and dynamics of cellular microcompartments, Osnabrück, Germany, 21.-22.9.2012
2012: Bartölke, R. Wieczorek, H. Vitavska, O. Novel insights into the SLC45 gene family of putative sugar transporters, Annual Meeting of the German Physiological Society, Dresden, Germany, Abstract P275, 22.-25.3.2012
2011: Blake-Palmer, K.G., Bartölke, R. Hiemstra, T.F. Karet, F.E. Towards understanding regulation of the human vacuolar H+ ATPase: The C subunit is phosphorylated by protein kinase A. British Renal Society/ Renal Association intergrated conference, Birmingham, England. Abstract S19(T), 2011
Funding/Fellowships/Awards
2016 – 2019: DFG individual research fellowship
2013 – 2014: Completion grant from the female promotion pool, University of Osnabrueck
2010 – 2013: Lichtenberg Fellowship
2010: Lower Saxony Scholarship Award
2009: Erasmus traineeship grant
2009: Hans Mühlenhoff travel grant