2024

Weihrauch T, Melo RCN, Gray N, Voehringer D, Weller PF, Raap U. Eosinophil extracellular vesicles and DNA traps in allergic inflammation. Front Allergy. 2024 Aug 1;5:1448007. doi: 10.3389/falgy.2024.1448007. PMID: 39148911 ; PMCID: PMC11324581. 

Weihrauch T, Gray N, Wiebe D, Schmelz M, Limberg M.M^†, Raap, U^†. TRPV1 Channel in Human Eosinophils: Functional Expression and Inflammatory Modulation. Int. J. Mol. Sci. 2024, 25(3):1922. https://doi.org10.3390/ijms25031922; ^†equal contribution

Gray N, Wiebe D, Weihrauch T, Raap U, Limberg MM. Density Gradient Centrifugation-Independent Purification of Human Basophils. Curr Protoc. 2024 Feb;4(2):e991. doi: 10.1002/cpz1.991. PMID: 38358026.

Kotnik N, Langner A, Meyer NH, Pas HH, Gibbs BF, Meijer JM, Diercks GFH, Horváth B, Raap U. Infiltration analysis of eosinophils and basophils and co-expression of CD69, CD63, IL-31 and IgE in patients with bullous and non-bullous pemphigoid. J Eur Acad Dermatol Venereol. 2023 Oct 31. doi: 10.1111/jdv.19593. Epub ahead of print. PMID: 37907267.

2023

Stahl LS, Wolters AC, Kautz O, Patsinakidis N, Raap U. Flammenfiguren – Eosinophile, die die Haut in Brand setzen [Flame figures-eosinophils setting the skin on fire]. Dermatologie (Heidelb). 2023 Sep 20. German. doi: 10.1007/s00105-023-05216-4. Epub ahead of print. PMID: 37728797.

Augustin M, Zeidler C, von Kiedrowski R, Metz M, Darsow U, Raap U, Legat FJ, Sebastian M, Weisshaar E, Ständer S. Indication for systemic therapy in chronic prurigo: Annotated checklist for practice. J Dtsch Dermatol Ges. 2023 Sep 18. doi: 10.1111/ddg.15152. Epub ahead of print. PMID: 37723931.

Moñino-Romero S, Kolkhir P, Szépfalusi Z, Schoepke N, Metz M, Asero R, Ferrer M, Gimenez-Arnau A, Grattan CEH, Jakob T, Konstantinou GN, Raap U, Staubach P, Zhang K, Bindslev-Jensen C, Daschner A, Kinaciyan T, Makris M, Marrouche N, Schmid-Grendelmeier P, Sussman G, Toubi E, Maurer M, Altrichter S. (2023) In chronic spontaneous urticaria soluble FcεRI is elevated and linked to atopy and chronic inducible urticaria. Clin Transl Allergy. 2023 Jul;13(7):e12272. doi: 10.1002/clt2.12272. PMID: 37488737; PMCID: PMC10314276.

Augustin M, Zeidler C, von Kiedrowski R, Metz M, Darsow U, Raap U, Legat FJ, Sebastian M, Weisshaar E, Ständer S. (2023) [Indikation zur Systemtherapie bei chronischer Prurigo: Kommentierte Checkliste für die Praxis]. J Dtsch Dermatol Ges. 2023 Jul;21(7):822-824. German. doi: 10.1111/ddg.15152_g. PMID: 37427739.

Limberg MM, Weihrauch T (joint 1st), Gray N, Ernst N, Hartmann K, Raap U. (2023) Eosinophils, Basophils, and Neutrophils in Bullous Pemphigoid. Biomolecules 13, 1019. doi.org/10.3390/biom13071019.

Zeidler C, Raap U, Witte F, Ständer S. (2023) "Clinical aspects and management of chronic itch". J Allergy Clin Immunol. 2023 May 11:S0091-6749(23)00569-9. doi: 10.1016/j.jaci.2023.04.018. Online ahead of print.PMID: 37178730 Review.

Raap U^†, Limberg MM^†, Kridin K, Ludwig RJ. (2023) Pruritus Is Associated with an Increased Risk for the Diagnosis of Autoimmune Skin Blistering Diseases: A Propensity-Matched Global Study. Biomolecules 2023 Mar 6;13(3):485. doi: 10.3390/biom13030485 PMID: 36979421.^†equal contribution

Weihrauch T, Limberg MM, Gray N, Schmelz M, Raap U. (2023) Neurotrophins: Neuroimmune Interactions in Human Atopic Diseases. International Journal of Molecular Sciences. 2023; 24(7):6105. https://doi.org/10.3390/ijms24076105.

Brans R, Schröder-Kraft C, Bauer A, Weisshaar E, Skudlik C, Geier J; IVDK. (2023) Contact sensitizations in massage therapists with occupational contact dermatitis: Patch test data of the Information Network of Departments of Dermatology, 2008-2020. Contact Dermatitis. 2023 Jan;88(1):43-53. doi: 10.1111/cod.14218. Epub 2022 Oct 4. PMID: 36088572.

2022

Gray N, Limberg MM, Wiebe D, Weihrauch T, Langner A, Brandt N, Bräuer AU, Raap U. (2022) Differential Upregulation and Functional Activity of S1PR1 in Human Peripheral Blood Basophils of Atopic Patients. Int. J. Mol. Sci. 2022, 23(24), 16117; https://doi.org/10.3390/ijms232416117 (registering DOI).

Papakonstantinou E, Fischer J, Limberg MM, Diercks GFH, Horvath B, Raap U. (2022) [Eosinophilic dermatoses] Dermatologie (Heidelb). 2022 Nov 15. doi: 10.1007/s00105-022-05071-9. Online ahead of print.

Worm M, Alexiou A, Bauer A, Treudler R, Wurpts G, Dickel H, Buhl T, Müller S, Jung A, Brehler R, Fluhr J, Klimek L, Mülleneisen N, Pfützner W, Raap U, Roeseler S, Schuh S, Timmermann H, Heine G, Wedi B, Brockow K. (2022) Management of suspected and confirmed COVID-19 (SARS-CoV-2) vaccine hypersensitivity. Allergy. 2022 Nov;77(11):3426-3434. doi: 10.1111/all.15414. Epub 2022 Jul 4. PMID: 35722723.

Ständer S, Zeidler C, Augustin M, Darsow U, Kremer AE, Legat FJ, Koschmieder S, Kupfer J, Mettang T, Metz M, Nast A, Raap U, Schneider G, Ständer H, Streit M, Schut C, Weisshaar E (2022) S2k guideline: Diagnosis and treatment of chronic pruritus. J Dtsch Dermatol Ges. 2022 Oct;20(10):1387-1402. doi: 10.1111/ddg.14830. PMID: 36252071.

Ständer S, Zeidler C, Augustin M, Darsow U, Kremer AE, Legat FJ, Koschmieder S, Kupfer J, Mettang T, Metz M, Nast A, Raap U, Schneider G, Ständer H, Streit M, Schut C, Weisshaar E. (2022) S2k Leitlinie: Diagnostik und Therapie des chronischen Pruritus. J Dtsch Dermatol Ges. 2022 Oct;20(10):1386-1402. doi: 10.1111/ddg.14830_g. PMID: 36252075.

Brans R, Schröder-Kraft C, Bauer A, Weisshaar E, Skudlik C, Geier J, IVDK (2022) Contact sensitizations in massage therapists with occupational contact dermatitis: patch test data of the Information Network of Departments of Dermatology (IVDK), 2008 to 2020. Contact Dermatitis. 2022 Sep 11.doi: 10.1111/cod.14218. Online ahead of print.

Metz M, Raap U (2022) [Novel aspects of the current guideline for chronic pruritus] Review Dermatologie (Heidelb). 2022 Aug;73(8):609-612. doi: 10.1007/s00105-022-05015-3. Epub 2022 Jun 9.

Asano K, Tamari M, Zuberbier T, Yasudo H, Morita H, Fujieda S, Nakamura Y, Traidl S, Hamelmann E, Raap U, Babina M, Nagase H, Okano M, Katoh N, Ebisawa M, Renz H, Izuhara K, Worm M (2022) Diversities of allergic pathologies and their modifiers: Report from the second DGAKI-JSA meeting. Allergol Int. 2022 Jul;71(3):310-317. doi: 10.1016/j.alit.2022.05.003. Epub 2022 Jun 2.

Worm M, Alexiou A, Bauer A, Treudler R, Wurpts G, Dickel H, Buhl T, Müller S, Jung A, Brehler R, Fluhr J, Klimek L, Mülleneisen N, Pfützner W, Raap U, Roeseler S, Schuh S, Timmermann H, Heine G, Wedi B, Brockow K. Management of suspected and confirmed COVID-19 (SARS-CoV-2) vaccine hypersensitivity. Allergy. 2022 Jun 20. doi: 10.1111/all.15414. Online ahead of print.PMID:35722723.

De Prins L, Raap U, Mueller T, Schmid-Grendelmeier P, Haase CH, Backer V, Fokkens W, Benoist LB, Prokopakis E, Hopkins C, Claeys N, Teeling T, Cypers L, Cools L, Bjermer LH, Diamant Z, Wahn U, Scadding G, Bachert C, Patel SR, Van Staeyen E, Hellings P. (2022) White Paper on European Patient Needs and Suggestions on Chronic Type 2 Inflammation of Airways and Skin by EUFOREA. Front Allergy. 2022 Jun 2;3:889221. doi: 10.3389/falgy.2022.889221. eCollection 2022.PMID:35769567.

Asano K, Tamari M, Zuberbier T, Yasudo H, Morita H, Fujieda S, Nakamura Y, Traidl S, Hamelmann E, Raap U, Babina M, Nagase H, Okano M, Katoh N, Ebisawa M, Renz H, Izuhara K, Worm M. (2022) Diversities of allergic pathologies and their modifiers: Report from the second DGAKI-JSA meeting. Allergol Int. 2022 Jun 2:S1323-8930(22)00044-2. doi: 10.1016/j.alit.2022.05.003. Online ahead of print. PMID: 35662539.

Oláh P, Szlávicz E, Kuchner M, Nemmer J, Zeeuwen P, Lefèvre-Utile A, Fyhrquist N, Prast-Nielsen S, Skoog T, Serra A, Rodríguez E, Raap U, Meller S, Gyulai R, Hupé P, Kere J, Levi-Schaffer F, Tsoka S, Alexander H, Nestle FO, Schröder JM, Weidinger S, van den Bogaard E, Soumelis V, Greco D, Barker J, Lauerma A, Ranki A, Andersson B, Alenius H, Homey B.Oláh P, et al. (2022) Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation. J Dermatol Sci. 2022 Apr 15:S0923-1811(22)00097-4. doi: 10.1016/j.jdermsci.2022.04.007. Online ahead of print.J Dermatol Sci. 2022. PMID: 35537882.

Noubissi Nzeteu GA, Schlichtner S, David S, Ruppenstein A, Fasler-Kan E, Raap U, Sumbayev VV, Gibbs BF, Meyer NH.Noubissi Nzeteu GA, et al. (2022) Macrophage Differentiation and Polarization Regulate the Release of the Immune Checkpoint Protein V-Domain Ig Suppressor of T Cell Activation. Front Immunol. 2022 May 11;13:837097. doi: 10.3389/fimmu.2022.837097. eCollection 2022.Front Immunol. 2022. PMID: 35634346 Free PMC article.

Worm M, Raap U. (2022) [Food allergy: a diagnostic and therapeutic challenge]. Hautarzt. 2022 Mar;73(3):177-178. doi: 10.1007/s00105-022-04950-5. Epub 2022 Mar 1. PMID: 35230456.

Eberlein B, Mathes S, Fischer J, Darsow U, Biedermann T, Brockow K. (2022) Do basophil activation tests help elucidate allergic reactions to the ingredients in COVID-19 vaccines? Allergy. 2022, accepted.

Chakrapani N, Fischer J, Swiontek K, Codreanu-Morel F, Hannachi, Morisset M, Mugemana C, Bulaev D, Blank S, Bindslev-Jensen C, Biedermann T, Ollert M, Hilger C. (2022) α-Gal present on both glycolipids and glycoproteins contributes to the immune response in meat allergic patients. J Allergy Clin Immunol. 2022, accepted.

Fischer J, Reepschläger T, Schricker T, Raap U. (2022) [Alpha-gal syndrome: Overview of clinical presentation and pathophysiology]. Hautarzt. 2022 Mar;73(3):195-200. doi: 10.1007/s00105-022-04943-4. Epub 2022 Feb 4. PMID: 35119482.

Schlichtner S, Yasinska IM, Ruggiero S, Berger SM, Aliu N, Prunk M, Kos J, Meyer NH, Gibbs BF, Fasler-Kan E, Sumbayev VV. (2022) Expression of the Immune Checkpoint Protein VISTA Is Differentially Regulated by the TGF-β1 - Smad3 Signaling Pathway in Rapidly Proliferating Human Cells and T Lymphocytes. Front Med (Lausanne). 2022 Feb 10;9:790995. doi: 10.3389/fmed.2022.790995. eCollection 2022.

Stenger F, Seidel P, Schricker T, Volc S, Fischer J. (2022) Could cat flea bites contribute to alpha-gal serum IgE levels in humans? J Investig Allergol Clin Immunol. 2022 Jan 24:0. doi: 10.18176/jiaci.0784. Epub ahead of print. PMID: 35088764.

Geier J, Ballmer-Weber B, Buhl T, Rieker-Schwienbacher J, Mahler V, Dickel H, Schubert S; IVDK. Is benzyl alcohol a significant contact sensitizer? J Eur Acad Dermatol Venereol. 2022 Jan 26. doi: 10.1111/jdv.17968. Online ahead of print. PMID: 35080274.

Gray N, Limberg MM, Bräuer AU, Raap U. (2022) Novel functions of S1P in chronic itchy and inflammatory skin diseases. J Eur Acad Dermatol Venereol. 2022 Mar;36(3):365-372. doi: 10.1111/jdv.17764. Epub 2021 Nov 12.

2021

Brockow K, Mathes S, Fischer J, Volc S, Darsow U, Eberlein B, Biedermann T. (2021) Experience with polyethylene glycol allergy-guided risk management for COVID-19 vaccine anaphylaxis. Allergy. 2021 Nov 22. doi: 10.1111/all.15183. Epub ahead of print. PMID: 34806775.

Kellner C, Lutz S, Oberg HH, Wesch D, Otte A, Diemer KJ, Wilcken H, Bauerschlag D, Glüer CC, Wichmann C, Kabelitz D, Leusen JHW, Klausz K, Humpe A, Gramatzki M, Peipp M. (2021) Tumor cell lysis and synergistically enhanced antibody-dependent cell-mediated cytotoxicity by NKG2D engagement with a bispecific immunoligand targeting the HER2 antigen. Biol Chem. 2021 Oct 29. doi: 10.1515/hsz-2021-0229. Online ahead of print.PMID: 34717050.

Otte A, Müller HL. (2021) Childhood-onset Craniopharyngioma. J Clin Endocrinol Metab. 2021 Sep 27;106(10):e3820-e3836. doi: 10.1210/clinem/dgab397.PMID: 34086900 Review.

Burger R, Otte A, Brdon J, Peipp M, Gramatzki M. (2021) Dual intracellular targeting by ruxolitinib and the Mcl-1 inhibitor S63845 in interleukin-6-dependent myeloma cells blocks. Haematologica. 2021 Sep 1;106(9):2507-2510. doi: 10.3324/haematol. 2020.276865.PMID: 33882638.

Traidl S, Werfel T, Ruëff F, Simon D, Lang C, Geier J; IVDK. (2021) Patch test results in patients with suspected contact allergy to shoes: Retrospective IVDK data analysis 2009-2018. Contact Dermatitis. 2021 Sep;85(3):297-306. doi: 10.1111/cod.13868 Epub 2021 May 11. PMID: 33882155.

Schlichtner S, Meyer NH, Yasinska IM, Aliu N, Berger SM, Gibbs BF, Fasler-Kan E, Sumbayev VV. (2021) Functional role of galectin-9 in directing human innate immune reactions to Gram-negative bacteria and T cell apoptosis. Int Immunopharmacol. 2021 Nov;100:108155. doi: 10.1016/j.intimp.2021.108155. Epub 2021 Sep 17.

Peters F, Rahn S, Mengel M, Scharfenberg F, Otte A, Koudelka T, Wagner EF, Wunderlich FT, Haase M, Naumann R, Tholey A, Becker-Pauly C. (2021) Syndecan-1 shedding by meprin β impairs keratinocyte adhesion and differentiation in hyperkeratosis. Matrix Biol. 2021 Aug;102:37-69. doi: 10.1016/j.matbio.2021.08.002. Epub 2021 Sep 8.PMID: 34508852.

Gubensäk N, Schrank E, Hartlmüller C, Göbl C, Falsone FS, Becker W, Wagner GE, Pulido S, Meyer NH, Pavkov-Keller T, Madl T, Reidl J, Zangger K. (2021) Structural and DNA-binding properties of the cytoplasmic domain of Vibrio cholerae transcription factor ToxR. J Biol Chem. 2021 Oct;297(4):101167. doi: 10.1016/j.jbc.2021.101167]. Epub 2021 Sep 4.

Boekhoff S, Bison B, Genzel D, Eveslage M, Otte A, Friedrich C, Flitsch J, Müller HL. (2021) Cerebral Infarction in Childhood-Onset Craniopharyngioma Patients: Results of KRANIOPHARYNGEOM 2007. Front Oncol. 2021 Jul 14;11:698150. doi: 10.3389/fonc.2021.698150. eCollection 2021.PMID: 34336685.

Klausz K, Cieker M, Kellner C, Rösner T, Otte A, Krohn S, Lux A, Nimmerjahn F, Valerius T, Gramatzki M, Peipp M. (2021) Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy. Haematologica. 2021 Jul 1;106(7):1857-1866. doi: 10.3324/haematol.2020.251371.PMID: 32499243.

Teo Hansen Selnø A, Schlichtner S, Yasinska IM, Sakhnevych SS, Fiedler W, Wellbrock J, Berger SM, Klenova E, Gibbs BF, Fasler-Kan E, Sumbayev VV. (2021) High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells. Front Immunol. 2021 Jun 21;12:675731. doi: 10.3389/fimmu.2021.675731. eCollection 2021. PMID: 34234778.

Lamberts A, Kotnik N, Diercks GFH, Meijer JM, Di Zenzo G, Pas HH, Jonkman MF, Gibbs BF, Raap U, Horváth B. (2021) IgE autoantibodies in serum and skin of non-bullous and bullous pemphigoid patients. J Eur Acad Dermatol Venereol. 2021 Apr;35(4):973-980. doi: 10.1111/jdv.16996. Epub 2020 Nov 17. PMID: 33058320.

Ruppenstein A, Limberg MM, Loser K, Kremer AE, Homey B, Raap U (2021) Involvement of Neuro-Immune Interactions in Pruritus With Special Focus on Receptor Expressions. Front. Med., 18 February 2021 | doi.org/10.3389/fmed.2021.627985.

Nemmer JM, Kuchner M, Datsi A, Oláh P, Julia V, Raap U, Homey B. (2021) Interleukin-31 Signaling Bridges the Gap Between Immune Cells, the Nervous System and Epithelial Tissues. Review Front Med (Lausanne) . 2021 Feb 10;8:639097.doi: 10.3389/fmed.2021.639097. eCollection 2021.

Geier J, Schubert S, Schnuch A, Szliska C, Weisshaar E, Kränke B, Werfel T, Ruëff F, Schröder-Kraft C, Buhl T. (2021) A negative breakdown test in a fragrance mix I-positive patient does not rule out contact allergy to its fragrance constituents. Contact Dermatitis. 2021 Feb 3.doi: 10.1111/cod.13803. Online ahead of print.

Renz H, Bachert C, Berek C, Hamelmann E, Levi-Schaffer F, Raap U, Simon HU, Ploetz S, Taube C, Valent P, Voehringer D, Werfel T, Zhang N, Ring J.Harald R. (2021) Physiology and Pathology of Eosinophils: Recent Developments. Scand J Immunol. 2021 Feb 23:e13032. doi: 10.1111/sji.13032. Online ahead of print.

Welzel J, Breuer G, Geilen C C, Raap U, Schley G, Schultz E, Schwarz S, Stadler R, Thieme D, Zouboulis C C (2021) How to Become a University Hospital? New Ways of Studying Medicine in Germany. Akt. Dermatol 2021; 47: 27-34 DOI 10.1055/a-1262-2073 ISSN 0340-2541.

Zouboulis C C, Geilen C C, Grunewald S, Kauczok C, Raap U, Sander C, Sárdy M, Welzel J. (2021) Structure oft he Dermatology Departments and Teaching in Dermatology at the New Universities in Germany. Akt Dermatol 2021; 47: 35-42 DOI 10.1055/a-1262-2086. ISSN 0340-2541.

Worm M, Bauer A, Wedi B, Treudler R, Pfuetzner W, Brockow K, Buhl T, Zuberbier T, Fluhr J, Wurpts G, Klimek L, Jacob T, Merk HF, Mülleneisen N, Roeseler S, Dickel H, Raap U, Kleine-Tebbe J. (2021) Practical recommendations for the allergological risk assessment of the COVID-19 vaccination - a harmonized statement of allergy centers in Germany. Allergol Select. 2021 Jan 26;5:72-76. doi: 10.5414/ALX02225E. eCollection 2021.

Duderstadt S, Raap U, Patsinakidis N (2021) Rapid therapeutic response of palmoplantar pustulosis under biologic treatment with guselkumab. Dermatol Ther. 2021 Jan 21;e14792. doi: 10.1111/dth.14792. Online ahead of print.

Kleiner S, Rüdrich U, Gehring M, Loser K, Eiz-Vesper B, Noubissi Nzeteu G, Patsinakidis N, Meyer NH, Gibbs BF, Raap U (2021) Human basophils release the anti-inflammatory cytokine IL-10 following stimulation with α-melanocyte-stimulating hormone. J Allergy Clin Immunol. 2021 Jan 15;S0091-6749(21)00009-9.doi: 10.1016/j.jaci.2020.12.645. Online ahead of print.

2020

Selnø ATH, Schlichtner S, Yasinska IM, Sakhnevych SS, Fiedler W, Wellbrock J, Klenova E, Pavlova L, Gibbs BF, Degen M, Schnyder I, Aliu N, Berger SM, Fasler-Kan E, Sumbayev VV. (2020) Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 expression in human cancer and embryonic cells. Aging (Albany NY). 2020 Dec 8;12(23):23478-23496. doi:10.18632/aging.202343.

Yasinska IM, Meyer NH, Schlichtner S, Hussain R, Siligardi G, Casely-Hayford M, Fiedler W, Wellbrock J, Desmet C, Calzolai L, Varani L, Berger SM, Raap U, Gibbs BF, Fasler-Kann E, Sumbayev VV. (2020) Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity. Front. Immunol., 20 November 2020 | doi.org/10.3389/fimmu.2020.580557.

Patsinakidis N, Meyer NH, Raap U. (2020) [Psoriasis] MMW Fortschr Med. Nov;162(Suppl 3):43-50. doi: 10.1007/s15006-020-1458-8.

Lamberts A, Kotnik N, Diercks GFH, Meijer JM, Di Zenzo G, Pas HH, Jonkman MF, Gibbs BF, Raap U, Horváth B. (2020) IgE autoantibodies in serum and skin of nonbullous and bullous pemphigoid patients. J Eur Acad Dermatol Venereol 2020 Oct 15. doi: 10.1111/jdv.16996. Online ahead of print.

Köthe A, Patsinakidis N, Raap U. (2020) Fixes bullöses Arzneimittelexanthem. Akt Dermatol; 46 (08/09):344.

Kotnik N, El-Sourani N, Raap U, Raab HR, Bockhorn M, Meyer H, Troja A. (2020) Expression of MicroRNA in Locoregional Recurrent Rectal Cancer. Anticancer Res. 2020 May;40(5):2947-2953. doi: 10.21873/anticanres.14273.PMID: 32366447

Guseva D, Rüdrich U, Kotnik N, Gehring M, Patsinakidis N, Agelopoulos K, Ständer S, Homey B, Kapp A, Gibbs BF, Ponimaskin E, Raap U (2020). Neuronal branching of sensory neurons is associated with BDNF-positive eosinophils in atopic dermatitis. Clin Exp Allergy. 2020 Jan 10. doi: 10.1111/cea.13560. [Epub ahead of print]

Papakonstantinou E, Raap U (2020). Herpes Zoster Schwere Komplikationen verhindern. Der Deutsche Dermatologe 2020; 68 (2): 114-122.

Schnuch A, Schubert S, Lessmann H, Geier J; IVDK. (2020). The methylisothiazolinone epidemic goes along with changing patients' characteristics - After cosmetics, industrial applications are the focus. Contact Dermatitis. 2020 Feb;82(2):87-93. doi: 10.1111/cod.13414. Epub 2019 Nov 17.

2019

Meyer NH, Dellago H, Tam-Amersdorfer C, Merle DA, Parlato R, Gesslbauer B, Almer J, Gschwandtner M, Leon A, Franzmann TM, Grillari J, Kungl AJ, Zangger K, Falsone SF (2019) Structural Fuzziness of the RNA-Organizing Protein SERF Determines a Toxic Gain-of-interaction. J Mol Biol. 2019 Nov 30. pii: S0022-2836(19)30679-5. doi: 10.1016/j.jmb.2019.11.014. [Epub ahead of print].

Patsinakidis N, Kautz O, Gibbs BF, Raap U. (2019) Lupus erythematosus tumidus: clinical perspectives. Clin Cosmet Investig Dermatol. Oct 1;12:707-719. doi: 10.2147/CCID.S166723. eCollection 2019.

Meyer NH, Kotnik N, Meyer V, Gibbs BF, Raap U (2019) The Complexity of Pruritus Requires a Variety of Treatment Strategies. Current Treatment Options in Allergy September 2019, Volume 6, Issue 3, pp 189–199.

Gibbs BF, Patsinakidis N, Raap U. (2019) Role of the Pruritic Cytokine IL-31 in Autoimmune Skin Diseases. Front Immunol. Jun 21;10:1383. doi: 10.3389/fimmu.2019.01383. eCollection 2019. Review.

Yasinska IM, Sakhnevych SS, Pavlova L, Teo Hansen Selnø A, Teuscher Abeleira AM, Benlaouer O, Gonçalves Silva I, Mosimann M, Varani L, Bardelli M, Hussain R, Siligardi G, Cholewa D, Berger SM, Gibbs BF, Ushkaryov YA, Fasler-Kan E, Klenova E, Sumbayev VV. (2019) The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer. Front Immunol. 2019 Jul 11;10:1594. doi: 10.3389/fimmu.2019.01594.

Schoepke N, Asero R, Ellrich A, Ferrer M, Gimenez-Arnau A, Grattan CEH, Jakob T, Konstantinou GN, Raap U, Skov PS, Staubach P, Kromminga A, Zhang K, Bindslev-Jensen C, Daschner A, Kinaciyan T, Knol EF, Makris M, Marrouche N, Schmid-Grendelmeier P, Sussman G, Toubi E, Church MK, Maurer M. (2019) Biomarkers and clinical characteristics of autoimmune chronic spontaneous urticaria (aiCSU): Results of the PURIST Study. Allergy.  Jun 22. doi: 10.1111/all.13949. [Epub ahead of print].

Maurer M, Raap U, Staubach P, Richter-Huhn G, Bauer A, Oppel EM, Hillen U, Baeumer D, Reinhardt M, Chapman-Rothe N (2019) Antihistamine-resistant chronic spontaneous urticaria: 1-year data from the AWARE study. Clin Exp Allergy. 49(5):655-662. doi: 10.1111/cea.13309.

Bauer A, Geier J, Schreiber S, Schubert S; IVDK.Contact sensitization to plants of the Compositae family: Data of the Information Network of Departments of Dermatology (IVDK) from 2007 to 2016 (2019), Contact Dermatitis. 80(4):222-227. doi: 10.1111/cod.13169.

Merle DA, Witternigg A, Tam-Amersdorfer C, Hartlmüller C, Spreitzer E, Schrank E, Wagner-Lichtenegger S, Werzer O, Zangger K, Kungl AJ, Madl T, Meyer NH, Falsone SF. (2019), Increased Aggregation Tendency of Alpha-Synuclein in a Fully Disordered Protein Complex. J Mol Biol. 2019 Jun 28;431(14):2581-2598. doi: 10.1016/j.jmb.2019.04.031. Epub 2019 Apr 26.

Yasinska IM, Calzolai L, Raap U, Hussain R, Siligardi G, Sumbayev VV, Gibbs BF (2019) Targeting of Basophil and Mast Cell Pro-Allergic Reactivity Using Functionalised Gold Nanoparticles. Front Pharmacol. 29;10:333. doi: 10.3389/fphar.2019.00333.

Papakonstantinou E, Limberg MM (joint 1st ), Gehring M, Kotnik N, Kapp A, Gibbs BF, Raap U (2019) Neurological Disorders are Associated with Bullous Pemphigoid. J Eur Acad Dermatol Venereol. 33(5):925-929. doi: 10.1111/jdv.15444.

Tsianakas A, Zeidler C, Riepe C, Borowski M, Forner C, Gerss J, Metz M, Staubach P, Raap U, Kaatz M, Urban M, Luger TA, Ständer S (2019) Aprepitant in Anti-histamine-refractory Chronic Nodular Prurigo: A Multicentre, Randomized, Double-blind, Placebo-controlled, Cross-over, Phase-II trial (APREPRU). Acta Derm Venereol. doi: 10.2340/00015555-3120.

 

2018

Yasinska IM, Gonçalves Silva I, Sakhnevych S, Gibbs BF, Raap U, Fasler-Kan E, Sumbayev VV (2018) Biochemical mechanisms implemented by human acute myeloid leukemia cells to suppress host immune surveillance. Cellular & Molecular Immunology 15: 989-991.

Yasinska IM, Goncalves Silva I, Sakhnevych SS, Ruegg L, Hussain R, Siligardi G, Fiedler W, Wellbrock J, Bardelli M, Varani L, Raap U, Berger S, Gibbs BF, Fasler-Kan E, Sumbayev VV (2018) High mobility group box 1 (HMGB1) acts as an "alarmin" to promote acute myeloid leukaemia progression. Oncoimmunology 7: e1438109.

Rüdrich U, Gehring M, Papakonstantinou E, Rabenhorst A, Engmann J, Kapp A, Hartmann K, Meyer NH, Gibbs BF, Raap U (2018) Eosinophils are a Major Source of Interleukin-31 in Bullous Pemphigoid. Acta Derm Venereol. LID - 10.2340/00015555-2951.

Yasinska IM, Ceccone G, Ojea-Jimenez I, Ponti J, Hussain R, Siligardi G, Berger SM, Fasler-Kan E, Bardelli M, Varani L, Fiedler W, Wellbrock J, Raap U, Gibbs BF, Calzolai L, Sumbayev VV (2018) Highly specific targeting of human acute myeloid leukaemia cells using pharmacologically active nanoconjugates. Nanoscale 10: 5827-5833.

Varricchi G, Raap U, Rivellese F, Marone G, Gibbs BF (2018) Human mast cells and basophils-How are they similar how are they different? Immunol Rev 282: 8-34.

Meyer NH, Gibbs B, Schmelz M, Homey B, Raap U (2018) [Neurophysiology of atopic pruritus]. Hautarzt 69: 204-209.

Papakonstantinou E, Schacht V, Kapp A, Raap U (2018) Localized subepidermal blistering: not always bullous pemphigoid but a diagnostic challenge. J Dtsch Dermatol Ges 16: 205-207.

Steelant B, Seys SF, Van Gerven L, Van Woensel M, Farré R, Wawrzyniak P, Kortekaas Krohn I, Bullens DM, Talavera K, Raap U, Boon L, Akdis CA, Boeckxstaens G, Ceuppens JL, Hellings PW (2018) Histamine and T helper cytokine-driven epithelial barrier dysfunction in allergic rhinitis. J Allergy Clin Immunol., 141(3):951-963.

D'Ascola A, Bruschetta G, Zanghì G, Campo S, Medica P, Campana S, Ferlazzo G, Gibbs BF, Ferlazzo AM (2018) Changes in plasma 5-HT levels and equine leukocyte SERT expression in response to treadmill exercise. Research in Veterinary Science 118: 184-190.

Dal Cortivo G, Wagner GE, Cortelletti P, Padmanabha Das KM, Zangger K, Speghini A, Dell'Orco D, Meyer NH (2018) Luminescent and paramagnetic properties of nanoparticles shed light on their interactions with proteins. Sci Rep 8: 3420.

Korosec P, Gibbs BF, Rijavec M, Custovic A, Turner PJ (2018) Important and specific role for basophils in acute allergic reactions. Clin Exp Allergy 48: 502-512.

Siebenhaar F, Redegeld FA, Bischoff SC, Gibbs BF, Maurer M (2018) Mast Cells as Drivers of Disease and Therapeutic Targets. Trends in Immunology 39: 151-162.

Raap U, Weiß J. Exantheme. In Brunkhorst E, Schölmerich J (Eds), Differenztialdiagnostik und Differenzialtherapie in der Inneren Medizin. Urban&Fischer, Elsevier. 2018. pp 56-59. ISBN 978-437-42502-8

Hansen Selnø AT, Sumbayev VV, Raap U, Gibbs BF. Role of Histamine in Inflammatory Diseases. In Riccardi C, Levi-Schaffer F, Tiligada E (eds), Immunopharmacology and Inflammation. Springer Science & Business Media, New York, USA. 2018. pp.85-106. DOI: 10.1007/978-3-319-77658-3_4.

2017

Noll C, von Jan U, Raap U, Albrecht UV (2017) Mobile Augmented Reality as a Feature for Self-Oriented, Blended Learning in Medicine: Randomized Controlled Trial. JMIR Mhealth Uhealth 5: e139.

Ständer S, Zeidler C, Augustin M, Bayer G, Kremer AE, Legat FJ, Maisel P, Mettang T, Metz M, Nast A, Niemeier V, Raap U, Schneider G, Ständer HF, Staubach P, Streit M, Weisshaar E (2017) Guidelines for the diagnosis and treatment of chronic pruritus - update - short version. J Dtsch Dermatol Ges 15: 860-872.

Papakonstantinou E, Kapp A, Jonkman MF, Raap U (2017)  Intraepidermal neutrophilic dermatosis type of IgA pemphigus with circulating linear IgA disease antibodies associated with ulcerative colitis. J Eur Acad Dermatol Venereol 32(1):e10-e11.

Maurer M, Staubach P, Raap U, Richter-Huhn G, Bauer A, Ruëff F, Jakob T, Yazdi AS, Mahler V, Wagner N, Lippert U, Hillen U, Schwinn A, Pawlak M, Behnke N, Chaouche K, Chapman-Rothe N (2017) H1-antihistamine-refractory chronic spontaneous urticaria: it's worse than we thought - first results of the multicenter real-life AWARE study. Clin Exp Allergy. 47(5):684-692.

Raap U, Gehring M, Kleiner S, Rudrich U, Eiz-Vesper B, Haas H, Kapp A, Gibbs BF (2017) Human basophils are a source of - and are differentially activated by - IL-31. Clin Exp Allergy 47: 499-508.

Engmann J, Rudrich U, Behrens G, Papakonstantinou E, Gehring M, Kapp A, Raap U (2017) Increased Activity and Apoptosis of Eosinophils in Blister Fluids, Skin and Peripheral Blood of Patients with Bullous Pemphigoid. Acta Derm Venereol 97: 464-471.

Goncalves Silva I, Yasinska IM, Sakhnevych SS, Fiedler W, Wellbrock J, Bardelli M, Varani L, Hussain R, Siligardi G, Ceccone G, Berger SM, Ushkaryov YA, Gibbs BF, Fasler-Kan E, Sumbayev VV (2017) The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells. EBioMedicine 22: 44-57.

Korosec P, Turner PJ, Silar M, Kopac P, Kosnik M, Gibbs BF, Shamji MH, Custovic A, Rijavec M (2017) Basophils, high-affinity IgE receptors, and CCL2 in human anaphylaxis. J Allergy Clin Immunol 140: 750-758 e15.

 

2016

Papakonstantinou E, Raap U. (2016) Oral Cavity and Allergy; Meeting the Diagnostic and Therapeutic Challenge. Curr Oral Health Rep. 3(4):347-355.

Duan S, Wanke K, Wawrzyniak P, Meng Y, Kast JI, Rückert B, Rebane A, Xian M, Bindslev-Jensen C, Broesby-Olsen S, Raap U, Werfel T, Akdis M, Zhang L, Akdis CA.  (2016) Platelet-activating factor decreases skin keratinocyte tight junction barrier integrity. J Allergy Clin Immunol. 138(6):1725-1728.e3.

Raap U, Papakonstantinou E, Metz M, Lippert U, Schmelz M (2016) [Update on the cutaneous neurobiology of pruritus]. Hautarzt 67: 595-600.

Ständer S, Raap U (2016) [Pruritus : What is the future?]. Hautarzt 67: 594.

Kleiner S, Braunstahl GJ, Rudrich U, Gehring M, Eiz-Vesper B, Luger TA, Steelant B, Seys SF, Kapp A, Bohm M, Hellings PW, Raap U (2016) Regulation of melanocortin 1 receptor in allergic rhinitis in vitro and in vivo. Clin Exp Allergy 46: 1066-74.

Fölster-Holst R, Papakonstantinou E, Rudrich U, Buchner M, Pite H, Gehring M, Kapp A, Weidinger S, Raap U (2016) Childhood atopic dermatitis-Brain-derived neurotrophic factor correlates with serum eosinophil cationic protein and disease severity. Allergy 71: 1062-5.

Papakonstantinou E, Prasse A, Schacht V, Kapp A, Raap U. Pirfenidone-induced severe phototoxic reaction in a patient with idiopathic lung fibrosis (2016) J Eur Acad Dermatol Venereol. 30(8):1354-6.

Mommert S, Kleiner S, Gehring M, Eiz-Vesper B, Stark H, Gutzmer R, Werfel T, Raap U (2016) Human basophil chemotaxis and activation are regulated via the histamine H4 receptor. Allergy 71: 1264-73.

Papakonstantinou E, Kapp A, Raap U (2016) A mild form of dermatomyositis as a prodromal sign of lung adenocarcinoma: a case report. J Med Case Rep 10: 34.

Wyszynski R, Gibbs BF (joint 1st and corresponding author), Varani L, Iannotta D, Sumbayev VV. Interleukin-1 beta induces the expression and production of stem cell factor by epithelial cells (2016) Cell Mol Immunol, 13:47-56.

Feracci M, Foot JN, Grellscheid SN, Danilenko M, Stehle R, Gonchar O, Kang HS, Dalgliesh C, Meyer NH, Liu Y, Lahat A, Sattler M, Eperon IC, Elliott DJ, Dominguez C (2016) Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68. Nat Commun 7: 10355.

Fercher C, Keller W, Zangger K, Meyer NH (2016) 1H, 15N and 13C chemical shift assignment of the Gram-positive conjugative transfer protein TraHpIP501. Biomol NMR Assign 10: 163-6.

Fercher C, Probst I, Kohler V, Goessweiner-Mohr N, Arends K, Grohmann E, Zangger K, Meyer NH, Keller W (2016) VirB8-like protein TraH is crucial for DNA transfer in Enterococcus faecalis. Sci Rep 6: 24643.

Goncalves Silva I, Ruegg L, Gibbs BF, Bardelli M, Fruehwirth A, Varani L, Berger SM, Fasler-Kan E, Sumbayev VV (2016) The immune receptor Tim-3 acts as a trafficker in a Tim-3/galectin-9 autocrine loop in human myeloid leukemia cells. Oncoimmunology 5: e1195535.

Sumbayev VV, Goncalves Silva I, Blackburn J, Gibbs BF, Yasinska IM, Garrett MD, Tonevitsky AG, Ushkaryov YA Expression of functional neuronal receptor latrophilin 1 in human acute myeloid leukaemia cells (2016) Oncotarget 7(29):45575-45583.