Team

Kontakt

Forschungsgruppenleitung

Prof. Dr. med. Axel Heep

Prof. Dr. Torsten Plösch

Sekretariat

Christina Sobirey 

0441 798 4011

Wissenschaftliche Mitarbeiterin und Lehrkoordination Pädiatrie

Dr. rer. nat. Cornelia Hinz  

Wissenschaftlicher Mitarbeiter

 Dr. Matthias Lange

Doktoranden

Andriana Gialeli

Merle Hannah Böttger

Yannick Figura

Team

Forschungsgruppenleitung

Prof. Dr. med. Axel Heep

Biography

Professor of Paediatrics, University of Oldenburg (since 10/18)

Honorary Senior Clinical Lecturer at the Bristol Medical School, TranslationalHealth Sciences University of Bristol, UK, (since 31/10/2011)

Fellow of the Royal College for Paediatrics and Child Health (01/04/2013)

Research:
Focus on my research activity is experimental and basic clinical research on neuropathological 
mechanismus contributing to the scenario of perinatal braininjury. Since 2015, Iam member/ collaborator
of Stem Ceels and the Neurodegeneration Research Group (Prof. J. Uney) University of Bristol, UK.
Ourresearch projects focus on characterisation of neural progenitor cells and molecular singalling
(microRNA, Cytokine / IGF pathways) in the cerebrospinalfluid of newborn infants.

Since 2008, I have been involved in research projects on functional MR imaging of preterm infants.
This research on functional neonatal neuroimaging is regarded to be pioneering work in this field and has given valuable contribution to the development of the Neonatal Neuroimaging project led by Prof. K. Luyt and Prof. R. Kauppinen at the CRIC Bristol an "Brain activity and development of connectivity in the neonatal brain at rest using ultrafast multiband MRI.
Current neonatal MRI studies focus on structural and functional development of brain connectivity and audio-visual integration in the developing brain.

Prof. Dr. Torsten Plösch

Biography

Torsten Plösch studied biology at the University of Oldenburg, Germany, and received his PhD in 2004 from the University of Groningen. He then established Epigenetic Programming as a new research focus at the University Medical Center Groningen. He was appointed as adjunct professor of experimental perinatology in 2019.

In 2020, Torsten joined the Perinatal Neurobiology group at Oldenburg university where he currently heads the lab facility. He published more than 80 peer reviewed papers. https://pubmed.ncbi.nlm.nih.gov/?term=plosch+t 

Torsten is a board member of the International Society for Developmental Origins of Health and Disease. Moreover, he serves as associate editor of the Journal of Developmental Origins of Health and Disease and Epigenetics Communications.

Sekretariat

Christina Sobirey

0441 798 4011 

Wissenschaftlicher Mitarbeiter

Dr. med. Matthias Lange

Biography

Matthias Lange studied medicine at the Medical University of Hannover (MHH), Germany. In 2015, he completed his training to be a pediatrician and then specialized in neonatology. In 2018, he started working at the department of pediatric intensive care at the University of Oldenburg. After a year of deepening his knowledge, he became senior physician in the department of neonatology in Oldenburg. He supervises medical students from the EMS in the context of either clinical-oriented publications or doctoral theses concerning neonatology or pediatric intensive care. In 2019, he joined the perinatal neurobiology group.

Cooperation:

Twincore Laboratory - Hanover

CAPNet- Foundation

Publications

Procalcitonin and valuable clinical symptoms in the early detection of neonatal late-onset bacterial infection. Bohnhorst B, Lange M, Bartels DB, Bejo L, Hoy L, Peter C. Acta Paediatr. 2012 Jan;101(1):19-25. Epub 2011 Aug 29.

Closed versus open endotracheal suctioning in extremly low-birth-weight neonates: a randomized, crossover trial. Pirr SM, Lange M, Hartmann C, Bohnhorst B, Peter C.Neonatology, 2013;103(2):124-30.Epub 2012 Dec 1.

Differential Diagnosis of headache und vertigo:Topical Minoxidil, self medication should be considered. Repkes L, Lange M, Stange M, Das AM. Journal of Headache & Pain Managment, 2016; Vol. 1 No.3:22

Severe methemoglobinemia caused by continous lidocaine infusion in a term neonate Bohnhorst B, Hartmann H, Lange M. Eur. J Paediatr Neurol. 2017 May;21(3):576-579

A Short Neonatologic Case Report: Salt Cod and Blue Lips. Bohnhorst B, Happel CM, Lange M. Klin Padiatr. 2018 Oct;230(6):336-338

Ultrasound assessment of gastric emptying time in preterm infants: A prospective observational Study. Beck CE, Witt L, Albrecht L, Winstroth AM, Lange M, Dennhardt N, Boethig D, Sümpelmann R. Eur J Anaesthesiol. 2019 Jun;36(6):406-410.

Der Pneumologische Fall: Akute respiratorische Insuffizienz zunächst unklarer Genese Lange M, Uphoff F, Seidenberg J. Pädiatrische Allergologie und Pulmologie 2019

Primary Haemophagocytic Lymphohistiocytosis (Chédiak-Higashi Syndrome) triggered by a acute SARS-CoV-2 infection in a 6-week-old infant. Lange M, Linden T, Müller HL, Flasskuehler AM, Koester H, Lehmberg K, Ledig S, Ehl S, Heep A, Beske F. Br J Haematol. 2021 Jun 16. doi: 10.1111/bjh.17669. ahead of print. PMID: 34132389.

Lack of capacity concerning the transport system of neonates and pediatric intensive care patients - A  regional survey in the north-western of Germany. Lange M. Schumacher S, Figura Y, Günther U, Mitzlaff B. DER NOTARZT, 2021 Jun 12.ahead of print

Wissenschaftlicher Mitarbeiter

Dr. med. habil Carsten Friedrich

Biography

Carsten Friedrich studied medicine at the Charité-Universitätsmedizin Berlin, Germany. During his doctoral thesis, pediatric residency (University-Medical Center Hamburg-Eppendorf, Germany) and pediatric-oncology fellowship (University-Medical Center Leipzig, Germany) he had a focus on experimental and clinical research in pediatric neuro-oncology. Since 2020 he works as the leading senior physician of the Department of General Pediatrics and Pediatric Hematology/Oncology, University Children's Hospital in Oldenburg, Germany.

Carsten Friedrich is excited to work on research questions that are interesting to the Perinatal Neurobiology group and the neuro-oncological community as pediatric brain tumor patients suffer from brain injuries due to the tumor, therapies or predisposition.

Wissenschaftliche Mitarbeiterin und Lehrkoordination Pädiatrie

Dr. rer.nat. Cornelia Hinz

Biography

Cornelia Hinz studied biology and received her PhD from the University of Oldenburg in 2012. Her previous work focused on the genetic background and molecular mechanisms of olfactory recognition and imprinting in the model organism Danio rerio. She investigated the relationship between genotype and phenotype of individuals and how early experiences in life can affect imprinting, signal recognition and the behavioral response. Since 2020 Cornelia Hinz organizes the pediatric education at the EMS in Oldenburg, works as a lecturer and joined the perinatal neurobiology group. 

Doktorandin

Andriana Gialeli

Biography

Andriana Gialeli studied Biology at the University of Athens, Greece (2014) and undertook a research internship in Center of Human Genetics at the KatholicUniversity of Leuven in Belgium (2014-2015).  Andriana completed a MSc in Molecular Neuroscience in 2016 at the University of Bristol, United Kingdom. Andriana’s MSc research project focused on the endogenous potential of brain recovery following cerebral haemorrhage in the developing brain. After her master, she continued working on the project as a research assistant at the Regenerative Medicine lab at the University of Bristol (2017-2020).

In May 2020, Andriana joined the Perinatal Neurobiology group at the University of Oldenburg as PhD student.

Publications

  • Buckner N, Kemp K, Scott H, Shi G, Rivers C, Gialeli A, Wong LF, Cordero-Llana Ó, Allen N, Wilkins A, Uney J. Abnormal scaffold attachment factor 1 expression and lockalization in spinocerebellar ataxia and Huntington’s chorea. Brain Pathol. 2020. doi: 10.1111/bpa.12872.
  • ·Spaull R, McPherson B, Gialeli A, Clayton A, Uney J, Heep A, Cordero-Llana Ó. Exosomes populate the cerebrospinal fluid of preterm infants with post-haemorrhagic hydrocephalus. Int J Dev Neurosci 2019. 73:59-65. doi: 10.1016/j.ijdevneu.2019.01.004.
(Stand: 26.07.2021)