Research Interests

• Clinical studies on addiction disorders and posttraumatic stress disorder in adolescents
• neurodevelopmental consequences of in-utero substance and trauma exposure
• epigenetic mechanisms
• stress system

Education          

2019 Postdoctoral lecture qualification (Habilitation), Medical Faculty, Friedrich–Alexander University Erlangen–Nürnberg. “Clinical and experimental studies on prenatal programming of psychiatric disorders in children and adolescents”

2010-2016 Residency and specialist qualification in child and adolescent psychiatry and psychotherapy (University Hospital of Erlangen, Central Institute of Mental Health in Mannheim, University Hospital, Frankfurt)

2006-2010 PhD Thesis: “Associative and non-associative fear in Posttraumatic Stress Disorder”. Max Planck Institute of Psychiatry, Munich, Germany (Magna cum laude)

2003-2005 Graduate Mastersprogram in Neural & Behavioural Sciences, International Max
Planck Research School, University of Tuebingen, Germany

1997-2003 Medical School, Samara State University, Russia (State Examination)

Employment

since 06/2023 Univ.-prof. and Director of the University Clinic for Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Carl von Ossietzky Universität Oldenburg

2017-2023 Head of the addiction outpatient clinic and an acute ward and research group leader “Stress and Substance use in Adolescents” in the Department of Child and Adolescent Psychiatry, University Hospital Carl Gustav Carus, Dresden, Germany

2016-2017 Maternity leave, parental leave

2014-2016 Research group leader "Neurobiology in child and adolescent psychiatry", Department of Child and Adolescent Mental Health, Universitätsklinikum, Erlangen

Clinical training, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, University Hospital, Goethe University, Frankfurt am Main, Germany

2013-2014 Clinical training, psychiatry, the Central Institute of Mental Health in Mannheim

2010-2013 Clinical training and research work, Department of Child and Adolescent Mental Health, University Hospital of Erlangen, Erlangen, Germany

Grants and Awards

2019-2022 Saxonian ministry of science and art (Grant Nr. 100362999): “Evaluation study of the Dresdner Multimodal Therapy for Adolescents with Chronic Substance Use” (DELTA). Total funding: approx. 600.000 Euro for 3 years

2018  DAAD Travel Award, 23rd World Congress of the International Association for Child
and Adolescent Psychiatry and Allied Professions (IACAPAP) 2018, Prague, Czech Republic

2017-2018 ELAN-Fonds for research, Faculty of Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany: „Effects of prenatal trauma on maternal hormone balance, placenta function and expression of HPA-axis related genes in fetal brain

2015-2016 Staedtler-Foundation: „Consequences of maternal alcohol consume during the pregnancy for children in primary school age“ Total funding: approx. 46.000 Euro  

2015 Travel Award, Universitätsklinikum Erlangen, Germany: World Congress of Biological Psychiatry 2015, Athens, Greece

2012-2013 ELAN-Fonds for research, Faculty of Medicine, Friedrich-Alexander-Universität Erlangen-Nürnberg: „Establishing an animal model of prenatal trauma exposure. Behavioral phenotyping and stress system changes” Total funding: 36.400 Euro 

2010 Poster Award of the Congress: Biological child and adolescent psychiatry, Ulm, Germany: „Associative and non-associative fear in the mouse model of Posttraumatic Stress disorder (PTSD)”

2003-2005 The German Academic Exchange Service (DAAD) fellowship for the Master program in Neural & Behavioural Sciences, International Max Planck Research School, University of Tübingen, Germany

Selected (most relevant) Publications 

https://pubmed.ncbi.nlm.nih.gov/?term=golub+y

Basedow, L. A., Kuitunen-Paul, S., Wiedman, M. F., Ehrlich, S., Roessner, V., & Golub, Y. (2021). Verbal learning impairment in adolescents with methamphetamine use disorder: a cross-sectional study. BMC Psychiatry, 21, 166. doi.org/10.1186/s12888-021-03169-3

Basedow, L. A., Kuitunen-Paul, S., Roessner, V., & Golub, Y. (2020). Traumatic Events and Substance Use Disorders in Adolescents. Frontiers in Psychiatry, 11, 559. https://doi.org/10.3389/fpsyt.2020.00559

Frey, S., Eichler, A., Stonawski, V., Kriebel, J., Wahl, S., Gallati, S., Goecke, T. W., Fasching, P. A., Beckmann, M. W., Kratz, O., Moll, G. H., Heinrich, H., Kornhuber, J., & Golub, Y. (2018). Prenatal Alcohol Exposure Is Associated With Adverse Cognitive Effects and Distinct Whole-Genome DNA Methylation Patterns in Primary School Children. Frontiers in Behavioral Neuroscience, 12, 125. doi.org/10.3389/fnbeh.2018.00125

Golub, Y., Canneva, F., Funke, R., Frey, S., Distler, J., von Hörsten, S., Freitag, C. M., Kratz, O., Moll, G. H., & Solati, J. (2016). Effects of In utero environment and maternal behavior on neuroendocrine and behavioral alterations in a mouse model of prenatal trauma. Developmental Neurobiology, 76(11), 1254-1265. doi.org/10.1002/dneu.22387

Golub, Y., Kuitunen-Paul, S., Panaseth, K., Stonawski, V.,  Frey, S., Steigleder, R., Grimm, J., Goecke, T. W., Fasching, P. A., Beckmann, M. W., Kornhuber, J., Kratz, O., Heinrich, H., Moll, G. H., & Eichler, A. (2019). Salivary and hair cortisol as biomarkers of emotional and behavioral symptoms in 6-9 year old children. Physiology & Behavior, 209, 112584. https://doi.org/10.1016/j.physbeh.2019.112584

Golub, Y., Schildbach, E.-M., Touma, C., Kratz, O., Moll, G. H., von Hörsten, S., & Canneva, F. (2019). Role of hypothalamus-pituitary-adrenal axis modulation in the stress-resilient phenotype of DPP4-deficient rats. Behavioural Brain Research, 356, 243-249. doi.org/10.1016/j.bbr.2018.08.029

Grimm, J., Stemmler, M., Golub, Y., Schwenke, E., Goecke, T. W., Fasching, P. A., Beckmann, M. W., Kratz, O., Moll, G. H., Kornhuber, J., & Eichler, A. (2020). The association between prenatal alcohol consumption and preschool child stress system disturbance. Developmental Psychobiology, 63(4), 687-697. doi.org10.1002/dev.22038

Kuitunen-Paul, S., Roessner, V., Basedow, L. A., & Golub, Y. (2021). Beyond the tip of the iceberg: A narrative review to identify research gaps on comorbid psychiatric disorders in adolescents with methamphetamine use disorder or chronic methamphetamine use. Substance Abuse, 42(1), 13-32. https://doi.org/10.1080/08897077.2020.1806183

Plank, A.-C., Frey, S., Basedow, L. A., Solati, J., Canneva, F., von Hörsten, S., Kratz, O., Moll, G. H., & Golub, Y. (2021). Prenatally traumatized mice reveal hippocampal methylation and expression changes of the stress-related genes Crhr1 and Fkbp5. Translational psychiatry, 11(1), 183. https://doi.org/10.1038/s41398-021-01293-y

Solati, J., Kleehaupt, E., Kratz, O., Moll, G. H., & Golub, Y. (2015). Inverse effects of lipopolysaccarides on anxiety in pregnant mice and their offspring. Physiology & Behavior, 139, 369-374. doi.org/10.1016/j.physbeh.2014.10.016

Books

Golub, Y., Basedow, L. A., Meiron-Zwipp, J., Kuitunen-Paul, S., Roessner, V. (2021). DELTA – Dresdner Multimodale Therapie für Jugendliche mit chronischem Suchtmittelkonsum. Hogrefe.